An example sensor includes: at least three capacitive sensing segments applied to the container; and a processor connected to the at least three capacitive sensing segments, the processor configured to: obtain respective capacitance measurements from the at least three capacitive sensing segments; determine an orientation of the container based on the capacitance measurements; and determine the amount of the substance based on the capacitance measurements.
G01F 23/263 - Indication ou mesure du niveau des liquides ou des matériaux solides fluents, p.ex. indication en fonction du volume ou indication au moyen d'un signal d'alarme en mesurant des variables physiques autres que les dimensions linéaires, la pression ou le poids, selon le niveau à mesurer, p.ex. par la différence de transfert de chaleur de vapeur ou d'eau en mesurant les variations de capacité ou l'inductance de condensateurs ou de bobines produites par la présence d'un liquide ou d'un matériau solide fluent dans des champs électriques ou électromagnétiques en mesurant les variations de capacité de condensateurs
G01C 9/20 - Mesure de l'inclinaison, p.ex. par clinomètres, par niveaux en utilisant des liquides l'indication étant basée sur l'inclinaison de la surface d'un liquide par rapport à son récipient
A method of volumetric additive manufacturing, comprising rotating a vial of photocurable resin; creating patterns of structured light images of an object to be manufactured so that the shape of the light dose distribution matches a desired shape of the object; correcting for diffusion within the vial; projecting the patterns of structured light images via a projector onto the rotating vial of photocurable resin thereby printing the object corrected for diffusion; and removing the printed object from the vial.
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
A method and apparatus are set forth for volumetric additive manufacturing (VAM) wherein light rays that are used to determine tomographic projections are modelled using ray tracing, in order to account for projector non-telecentricity and etendue in all three dimensions. The path of rays from each light source (e.g. pixel) are computed as they propagate through the VAM system. Optical effects such as refraction, transmission loss, absorption, etendue, and non-telecentricity are intrinsically accounted for via ray tracing. Using these rays, the required dose to solidify the photosensitive resin is computed.
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
22)); and, a reducing agent reactive with a free radical species (e.g., a peroxyl radical) formed from the polymerization inhibitor. The reducing agent permits faster printing of objects from the photoresin formulation in a volumetric additive manufacturing process to produce 3D objects of high fidelity.
C08L 33/04 - Homopolymères ou copolymères des esters
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
A volumetric additive manufacturing (VAM) process for producing a solid object having a surface layer of a multifunctional material patterned thereon involves: contacting a surface of a solid base object with a liquid composition containing a photo-initiator and a multifunctional material covalently graftable to the surface of the solid base object; and, selectively irradiating the composition at the surface of the solid base object with patterned light, the irradiating being tomographic, to initiate covalent grafting of the multifunctional material to the surface of the solid base object to pattern only a portion of the surface of the solid base object with a layer of the multifunctional material grafted thereon, where the portion of the surface of the solid base object corresponds to the selectively irradiated surface of the solid base object.
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
A method for additive manufacturing of an object having a three-dimensional structure formed from a photo-curable material, the method implemented by a computing device comprising a processor and a computer readable medium having instructions executable by the processor, the method comprising at least the steps of: (a) rotating a vial containing the photo-curable material in a path of a light beam at a predefined rotation speed: (b) calculating patterns associated with a 3D geometry of the object; (c) modulating a focal length of the beam within the photo- curable material while projecting the beam comprising the patterns into the photo- curable material to form the object.
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
A method for non-destructive in-situ determination of the R-value of a material at a mean temperature comprises maintaining three or more steady-state temperatures, each for a respective measurement period, measuring temperature and heat flow through the material, calculating R-values at each steady-state temperature and determining the R-value of the material at the mean temperature from the calculated R-values. A system for non-destructive in-situ determination of the R-value of a material at a mean temperature comprises a housing defining a chamber, a temperature control system for heating and cooling the chamber between three or more steady-state temperatures, heat flux transducers, temperature sensors and a computing device from controlling the temperature control system and comprising a data acquisition system for recording measurements from the heat flux transducers and the temperature sensors.
Provided is an enveloped virus-like particle (eVLP) comprising a substantially full-length recombinant SARS-CoV-2 spike (S) protein. The eVLP may further comprise an additional recombinant SARS-CoV-2 S protein having a different sequence, another recombinant viral antigen, or a recombinant non-viral protein. The eVLP is derived from an animal cell, such as a CHO cell, expressing the recombinant SARS-CoV-2 spike protein. Also provided are methods of producing such eVLPs, compositions including such eVLPs, and methods and uses for the induction of an immune response against a SARS-CoV-2 spike protein and/or prevention of COVID-19 or SARS-CoV-2 infection, employing such eVLPs.
HIS MAJESTY THE KING IN RIGHT OF CANADA, AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (Canada)
Inventeur(s)
Orth, Antony
Stewart, Terrence
Picard, Michel
Drouin, Marc-Antoine
Théberge, Francis
Abrégé
A target located method and apparatus for the detection of lasers directed at the target using neuromorphic cameras which improve the detection by use of defocus.
G01J 1/42 - Photométrie, p.ex. posemètres photographiques en utilisant des détecteurs électriques de radiations
H04N 25/47 - Capteurs d'images avec sortie d'adresse de pixel; Capteurs d'images commandés par événement; Sélection des pixels à lire en fonction des données d'image
10.
METHOD AND APPARATUS FOR EXTRACTING UNAMBIGUOUS UAV (E.G. DRONE) SIGNATURE USING HIGH-SPEED CAMERA
G01P 3/38 - Dispositifs caractérisés par l'emploi de moyens optiques, p.ex. en utilisant la lumière infrarouge, visible ou ultraviolette en utilisant des moyens photographiques
G01V 8/00 - Prospection ou détection par des moyens optiques
11.
3D-PRINTABLE PIEZOELECTRIC CERAMIC COMPOSITIONS WITH CARBON NANOMATERIALS
An extrudable ceramic composition comprises piezoelectric ceramic particles and carbon nanomaterial particles suspended in a carrier medium. A piezoelectric ceramic material is produced by curing the composition. The carbon nanomaterials are used as additives to extrudable ceramic compositions (e.g., piezoelectric compositions such as PZT/polymer composites, PZT/sol-gel composites, PZT emulsion pastes and the like). The addition of carbon nanomaterials imparts both beneficial rheological properties (shear thinning) and improved piezoelectric performance to the ceramic material.
C04B 35/491 - Produits céramiques mis en forme, caractérisés par leur composition; Compositions céramiques; Traitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxydes de zirconium ou d'hafnium ou de zirconates ou d'hafnates contenant également de l'oxyde de titane ou des titanates à base de zirconates de plomb et de titanates de plomb
B28B 1/14 - Fabrication d'objets façonnés à partir du matériau par simple coulée, le matériau n'étant ni alimenté sous pression, ni réellement compacté
B28B 1/54 - Fabrication d'objets façonnés à partir du matériau spécialement adaptée à la fabrication d'objets à partir de matériaux fondus, p.ex. laitier
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
C04B 35/63 - Préparation ou traitement des poudres individuellement ou par fournées utilisant des additifs spécialement adaptés à la formation des produits
C04B 35/653 - Procédés comportant une étape de fusion
An extrudable composition includes: an aqueous phase comprising acidic water and piezoelectric ceramic particles suspended in the water; and, an organic phase having an organic solvent, a curable polymer precursor or both an organic solvent and a curable polymer precursor. The composition is 3-D printable to form a self-supporting structure and may be infiltrated with an organic polymer material or cured so that the curable polymer precursor forms an organic polymer material thereby forming a piezoelectric composite having piezoelectric ceramic particles in a co-continuous phase.
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
C04B 35/491 - Produits céramiques mis en forme, caractérisés par leur composition; Compositions céramiques; Traitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxydes de zirconium ou d'hafnium ou de zirconates ou d'hafnates contenant également de l'oxyde de titane ou des titanates à base de zirconates de plomb et de titanates de plomb
C08K 3/01 - Emploi de substances inorganiques en tant qu'adjuvants caractérisées par leur fonction
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
H10N 30/084 - Mise en forme ou usinage de corps piézo-électriques ou électrostrictifs par moulage ou extrusion
The present document describes a pharmaceutical composition comprising a) a lipid nanoparticle operable to encapsulate a therapeutic agent, comprising a core and an external surface, said therapeutic agent being encapsulated within said core; said lipid nanoparticle having a size of said lipid nanoparticle of from about 30 to about 80 nm, or a pegylated lipid comprising a distearoyl-rac-glycerol (DSG) – PEG and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- (DSPE) – PEG - DBCO; or a combination of: a size of from about 30 to about 80 nm and a pegylated lipid comprising a DSG-PEG and DSPE-PEG-DBCO; and b) an antibody or antigen-binding fragment thereof operable to transmigrate the blood-brain barrier (BBB), wherein the antibody or antigen-binding fragment thereof comprises complementarity determining regions (CDR1, CDR2 and CDR3), operably linked to said external surface of said lipid nanoparticle.
A61K 31/7088 - Composés ayant au moins trois nucléosides ou nucléotides
A61K 47/14 - Esters d’acides carboxyliques, p.ex. acides gras monoglycérides, triglycérides à chaine moyenne, parabènes ou esters d’acide gras de PEG
A61K 47/24 - Composés organiques, p.ex. hydrocarbures naturels ou synthétiques, polyoléfines, huile minérale, gelée de pétrole ou ozocérite contenant des atomes autres que des atomes de carbone, d'hydrogène, d'oxygène, d'halogènes, d'azote ou de soufre, p.ex. cyclométhicone ou phospholipides
C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p.ex. oligonucléotides anti-sens
C12N 15/88 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p.ex. co-transformation utilisant la micro-encapsulation, p.ex. utilisant des vésicules liposomiques
14.
ANTIBODIES WITH ENGINEERED O-GLYCOSYLATION SEQUONS FOR SITE-SPECIFIC CONJUGATION
The present document describes antibodies or antigen-binding fragments that bind specifically to a target antigen, wherein the antibodies or antigen-binding fragments comprise complementarity determining regions (CDR1, CDR2 and CDR3) and an added O-glycosylation sequon glycosylated with an O-glycan having the general formula (I) : wherein R1is an initial N-acetylgalactosamine (GalNAc); n = 1, or 2; R2are each independently absent, galactose (Gal), GalNAc, N-Acetylglucosamine (GlcNAc), or a sialic acid; R3 are each independently absent, Gal or a sialic acid; and R4 are each independently absent or a sialic acid. Also described are compounds comprising the antibodies or antigen-binding fragments comprising a functional moiety operably linked to said O-glycan, compositions comprising the same, and methods of preparing such compounds.
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
C07K 1/107 - Procédés généraux de préparation de peptides par modification chimique de peptides précurseurs
C07K 9/00 - Peptides ayant jusqu'à 20 amino-acides, contenant des radicaux saccharide et comportant une séquence entièrement déterminée; Leurs dérivés
The present invention concerns new strains of cyanogenic bacteria, and more particularly alkali-tolerant Pseudomonas bacteria, that are useful to gold mining activities. These bacteria are useful to leach gold from any source including ores, concentrates or waste material. They have the ability to effectively produce cyanide at alkaline pH.
C12P 3/00 - Préparation d'éléments ou de composés inorganiques à l'exception du dioxyde de carbone
C22B 3/18 - Extraction de composés métalliques par voie humide à partir de minerais ou de concentrés à l'aide de micro-organismes ou d'enzymes, p.ex. de bactéries ou d'algues
C22B 11/08 - Obtention des métaux nobles par cyanuration
C07H 15/04 - Radicaux acycliques non substitués par des structures cycliques liés à un atome d'oxygène d'un radical saccharide
C07K 14/21 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Pseudomonadaceae (F)
C07K 14/34 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Corynebacterium (G)
C07K 14/195 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
17.
DEEP LEARNING BASED PREDICTION OF FABRICATION-PROCESS-INDUCED STRUCTURAL VARIATIONS IN NANOPHOTONIC DEVICES
A computer-implemented method comprising the steps of: with an imaging device, acquiring a plurality of images of structures of a fabricated device; preprocessing the plurality of images; creating at least one image dataset from the preprocessed plurality of images; generating a predictor model; training the predictor model with the at least one image dataset to identify structural features of the fabricated device with a propensity for fabrication anomalies.
G06V 10/70 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique
B82Y 40/00 - Fabrication ou traitement des nanostructures
G01N 23/2251 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p.ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux en utilisant des microsondes électroniques ou ioniques en utilisant des faisceaux d’électrons incidents, p.ex. la microscopie électronique à balayage [SEM]
G01N 37/00 - RECHERCHE OU ANALYSE DES MATÉRIAUX PAR DÉTERMINATION DE LEURS PROPRIÉTÉS CHIMIQUES OU PHYSIQUES - Détails non couverts par les autres groupes de la présente sous-classe
G06F 30/398 - Vérification ou optimisation de la conception, p.ex. par vérification des règles de conception [DRC], vérification de correspondance entre géométrie et schéma [LVS] ou par les méthodes à éléments finis [MEF]
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”
18.
MULTI-CHANNEL ANALOG-SIGNAL-INPUT TO DIGITAL-SIGNAL-OUTPUT DOWN-CONVERSION AND DIGITAL-SIGNAL-INPUT TO ANALOG-SIGNAL-OUTPUT UP-CONVERSION PHOTONICS MICROWAVE SYSTEMS BASED ON QUANTUM DOT MULTI-WAVELENGTH LASERS
Methods and systems for down-conversion of high frequency signals in millimeter-wave (mm-wave) communications and for up-conversion of high frequency signals in millimeter-wave (mm-wave) communications. A quantum dot multi-wavelength laser (QD MWL) source generates an optical signal comprising of a plurality of optical channels and allows flexible selection of the optical channels which can be used to generate and process RF signals in higher frequency bands of mm-wave spectrum including K-band, Ka-band V-band, W-band encompassing all 3GPP NR FR2 bands and even THz range depending on the channel spacing.
A computer-implemented method comprising the steps of: with an imaging device, acquiring a plurality of images of structures of a fabricated device; preprocessing the plurality of images; creating at least one image dataset from the preprocessed plurality of images; generating at least one of a predictor model and a corrector model; training the predictor model with the at least one image dataset to identify structural features of the fabricated device with a propensity for fabrication deviations, wherein the corrector model is useful for completing tasks comprising of at least: receiving a desired layout as input and generating a layout output, and automatically correcting the device design to minimize the impact of fabrication deviations on its operation.
G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”
G01R 31/28 - Test de circuits électroniques, p.ex. à l'aide d'un traceur de signaux
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
Volumetric Additive Manufacturing allows for the rapid printing of objects by transmitting images into a reservoir holding resin, using wavelengths of light assocaited with a photocuring characteristic of the resin. Feedback based control can be enabled through the use of optical scattering tomography based imaging of the object during the printing process. Through capturing a set of images representing the scattering of a non-curing light, an isosurface representing the object during printing can be generated. The differences between the isosurface and the expected shape of the object can be used as an input into a control process or they can be displayed to an operator so that printing can be terminated when the printing of the object is complete.
B33Y 50/00 - Acquisition ou traitement de données pour la fabrication additive
B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
G01B 11/25 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer des contours ou des courbes en projetant un motif, p.ex. des franges de moiré, sur l'objet
21.
COMPOSITIONS, DEVICES AND METHODS FOR TREATING CNS DISORDERS
Described herein are BBB-transporting fusion proteins, polynucleotides encoding the fusion proteins and mammalian cells genetically modified to express and secrete the fusion proteins, as well as compositions, implantable devices and device preparations comprising the fusion proteins or genetically modified cells secreting the fusion proteins, and methods of making and using the same for treating various CNS diseases and conditions, e.g., any mucopolysaccharidosis type with CNS manifestations.
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
Described herein are ARSB fusion proteins, polynucleotides encoding the fusion proteins and mammalian cells genetically modified to express and secrete the fusion proteins, as well as compositions, implantable devices and device preparations comprising the fusion proteins or genetically modified cells secreting the fusion proteins, and methods of making and using the same for treating MPS-6.
A composition comprising a mixture of two or more stereoisomers of a synthetic charged isoprenoid glycolipid of Formula (I), or a pharmaceutically acceptable salt thereof, in which n is 0 or 1, R and R' are independently hydrogen or hydroxyl, each Y is independently hydrogen or a sulfate group, and wherein at least one Y is a sulfate group, and less than 25% of the synthetic charged isoprenoid glycolipid molecules in the mixture comprise an archaeol moiety of the configuration (R)-2,3-bis(((3R,7R,11R)-3,7,11,15-tetramethylhexadecyl)oxy) propan-1-ol. Further provided are archaeosomes and immunogenic compositions comprising the composition,use of the composition as an adjuvant or immunostimulant, and processes for synthesizing the composition.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p.ex. par les adjuvants chimiques
A61K 31/08 - Ethers ou acétals acycliques, p.ex. paraformaldéhyde
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
C07C 41/14 - Préparation d'éthers par remplacement des substituants sur l'oxygène de la fonction éther par d'autres substituants, p.ex. par transéthérification
C07C 43/13 - Ethers saturés contenant des groupes hydroxyle ou O-métal
C07H 15/04 - Radicaux acycliques non substitués par des structures cycliques liés à un atome d'oxygène d'un radical saccharide
24.
A COMPOSITION FOR DISINFECTION AND A METHOD OF PREPARING A DISINFECTANT
2 2222 is doped to red-shift its absorption spectrum. The present specification further provides a method of preparing a disinfectant which contains a titanium dioxide nanoparticle and a dopant.
A61L 2/238 - Métaux ou alliages, p.ex. métaux oligodynamiques
A61L 2/232 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contact; Accessoires à cet effet utilisant des substances chimiques des substances solides, p.ex. des granules, des poudres, des blocs, des comprimés en couches ou revêtues
25.
DYNAMIC MICRO-OPTIC SECURITY DEVICES, THEIR PRODUCTION AND USE
Disclosed are devices with dynamic optical properties suitable for use as security or authentication devices, for example for documents or items of importance or value, in order to help prevent counterfeit of the same. Such devices, at least in selected embodiments, enable observation of dynamic changes or moving entities within the device by collective or enhanced imaging of the dynamic changes or moveable entities, the motion or position of which may otherwise be difficult to observe, or indiscernible to, the naked eye.
The disclosure relates to methods for diagnosing, detecting or screening for COVID-19 in a subject. The method comprises measuring the concentration of at least two sphingolipids in a blood sample. The sphingolipids are selected from Cer(d18:1/16:0), Cer(d18:1/26:0), 1-O-nervonoyl-Cer(d18:1/18:2), HexCer(d18:1/22:0), Cer(d18:1/18:0) and PE-Cer(d18:1/24:0). The method further comprises determining a ratio of the concentration of the at least two sphingolipids and comparing the ratio with a reference value, wherein a differential between the ratio and the reference value is indicative that the subject has or likely has COVID-19. Also provided is a kit for use with the method disclosed herein.
The present invention is directed to SARS-CoV-2 spike protein specific antibodies and antibody fragments, compositions comprising the antibodies or antibody fragments, and uses thereof. The anti-spike protein antibodies and antibody fragments may be specific for SARS-CoV-2 including current and emerging virus variants. The invention also includes methods of treating a SARS-CoV-2 infection, methods of capturing SARS-CoV-2 spike proteins, and methods of detecting SARS-CoV-2 spike proteins using the antibodies or antibody fragments.
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p.ex. émulsion, particule, complexe d’inclusion, stent ou kit
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
28.
METHODS AND APPARATUS FOR SELF-MAINTENANCE OF SATELLITE-INTEGRATED NETWORKS
A computer-implemented method for communications network maintenance, the method comprising the steps of: acquiring raw data associated with the communications network a plurality of datasets; preprocessing the raw data by converting the raw data into a predefined data format to form a plurality of datasets and correcting any inconsistencies in the plurality of datasets; training a neural network with the plurality of datasets to detect at least one of an anomalous event and a network anomaly event, and localizing the communications network anomaly event to infer at least one root cause for the communications network anomaly event; and creating and executing a self-maintenance scheme to mitigate against effects of the at least one of the anomalous event and the communications network anomaly event.
H04L 41/16 - Dispositions pour la maintenance, l’administration ou la gestion des réseaux de commutation de données, p.ex. des réseaux de commutation de paquets en utilisant l'apprentissage automatique ou l'intelligence artificielle
H04L 41/0631 - Gestion des fautes, des événements, des alarmes ou des notifications en utilisant l’analyse de la corrélation entre les notifications, les alarmes ou les événements en fonction de critères de décision, p.ex. la hiérarchie ou l’analyse temporelle ou arborescente
H04B 1/74 - TRANSMISSION - Détails des systèmes de transmission non caractérisés par le milieu utilisé pour la transmission pour augmenter la fiabilité, p.ex. en utilisant des canaux ou des appareils supplémentaires ou de réserve
A modulation method comprising steps of: a) generating a first signal having a first train of short pulses having a first frequency, and a second signal having a second train of short pulses having a second frequency, wherein each of the signals are associated with a negative or positive sign; b) maintaining a narrow frequency difference between the frequencies; c) imposing chirped modulation on each of the signals to achieve a desired spectral resolution, such that each signal is associated with a chirp having a first sign and a second sign; and d) switching between the signs for each signal over a frequency range, and detecting for each frequency of said frequency range, a spectral response resulting from a transfer of said modulation between the signals wherein the chirp sign of each of the signals is different, thereby obtaining hyperspectral data of said spectral response over said frequency range.
G01J 3/44 - Spectrométrie Raman; Spectrométrie par diffusion
G01N 22/00 - Recherche ou analyse des matériaux par l'utilisation de micro-ondes ou d'ondes radio, c. à d. d'ondes électromagnétiques d'une longueur d'onde d'un millimètre ou plus
30.
RAISED FLUIDIC CHANNELS AND METHODS OF MANUFACTURE
A ridge fluidic device comprising: a substrate and a fluidic component comprising at least one fluidic channel, wherein the at least one fluidic channel is adapted to conduct a fluid and retain the fluid within the at least one fluidic channel; wherein the at least one fluidic channel comprises porous material having a hydrophilic surface; and wherein the at least one fluidic channel is formed on the substrate via a deposition process.
Herein are provided anti-BCMA single domain antibodies (sdAb) prepared byte immunizing a llama with the ecto-domain of human B-cell maturation antigen (BCMA) that is preferentially expressed by mature B lymphocytes. By constructing a library of the heavy chain repertoire generated, VHH antibodies specific to the immunogen were isolated. The 13 unique example antibodies initially produced comprise CDR1, CDR2, and CDR3 sequences corresponding, respectively to SEQ NOs: 1-3, 4-6, 7-9, 10-12, 13-15, 16-18, 19-21, 22-24, 25-27, 28-30, 31-33, 34-36, 37-39; and related sequences. Also provided are multivalent antibodies comprising any one of the sdAbs, including bispecific T-cell engagers, bispecific killer cell engagers (BiKEs), and trispecific killer cell engagers (TriKEs). Also described are chimeric antigen receptors (CARs) for CAR-T therapy comprising any one of the aforementioned sdAbs. Uses of these molecules in the treatment of cancer or autoimmune diseases are also described, in particular hematological malignancies, such as multiple myeloma.
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 35/12 - Substances provenant de mammifères; Compositions comprenant des tissus ou des cellules non spécifiés; Compositions comprenant des cellules souches non embryonnaires; Cellules génétiquement modifiées
Here is disclosed isolated or purified monoclonal antibodies, or an antigen-binding fragments thereof, which binds to human CD3, and which comprises: a CDRH1 amino acid sequence of SEQ ID NO: 150, a CDRH2 amino acid sequence of SEQ ID NO: 151, a CDRH3 amino acid sequence of SEQ ID NO: 152, a CDRL1 amino acid sequence of SEQ ID NO: 153, a CDRL2 amino acid sequence of SEQ ID NO: 154, and a CDRL3 amino acid sequence of SEQ ID NO: 155. Also provided are recombinant polypeptides comprising said monoclonal antibody, or an antigen-binding fragment thereof, such as multivalent antibodies, including bispecific T-cell engagers. Also described are chimeric antigen receptors (CARs) for CAR-T therapy comprising any one of the monoclonal antibodies, or antigen-binding fragments thereof. Nucleic acids encoding the aforementioned antibodies, fragments, and polypeptides are also disclosed, along with therapeutic applications in the treatment of and autoinflammatory disease or cancer.
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
G01N 33/574 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour le cancer
G01N 33/577 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet faisant intervenir des anticorps monoclonaux
33.
RAIL ASSEMBLY, BOGIE, BOGIE WHEEL AND INFLATABLE SEAL ASSEMBLY
A rail assembly for use with a bogie wheel includes two rail segments having mating end segments abutting against each other, and joined by a connecting bolt that traverse the mating end segments. A bogie for use with a rail includes a support frame, a chassis movably attached to the support frame, and an elastomeric bearing disposed between and in bearing engagement with the support frame and the chassis, to limit movement of the chassis relative to the support frame. A bogie wheel includes a central hub adapted for direct mounting to a bogie chassis, a tread, and a bearing assembly permitting rotation of the tread relative to the hub. An inflatable seal assembly for sealing between a first member and a second member includes an inflatable bladder, a membrane attached to the first member, and a tension spring attached to the membrane to bias the membrane against the bladder.
E01B 25/00 - Voies pour types particuliers de chemins de fer
B61F 5/00 - SUSPENSIONS DES VÉHICULES FERROVIAIRES, p.ex. CHÂSSIS, BOGIES OU AMÉNAGEMENTS DES ESSIEUX DES ROUES; VÉHICULES FERROVIAIRES UTILISABLES SUR VOIES D'ÉCARTEMENT DIFFÉRENT; PRÉVENTION DES DÉRAILLEMENTS DE VÉHICULES FERROVIAIRES; COUVRE-ROUES, DÉBLAYEURS D'OBSTACLES OU DISPOSITIFS SIMILAIRES POUR VÉHICULES FERROVIAIRES - Détails de structure des bogies; Liaisons entre bogies et châssis du véhicule; Aménagements ou dispositifs pour ajuster ou permettre l'auto-ajustement des essieux des roues ou des bogies dans les courbes
E04H 5/00 - Bâtiments ou groupes de bâtiments à des fins industrielles ou agricoles
F16J 15/48 - Joints d'étanchéité par bague de garniture dilatée ou comprimée dans son logement par pression d'un fluide, p.ex. garnitures gonflables la pression provenant de celle existant dans l'organe à isoler
G02B 23/16 - Logements; Couvercles; Montures; Supports, p.ex. avec contrepoids
Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such compounds or pharmaceutical compositions.
A61K 51/10 - Anticorps ou immunoglobulines; Leurs fragments
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
35.
HUMANIZED ANTI-EGFRVIII ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS THEREOF
Antigen-binding agents such as humanized antibodies or antigen-binding fragments thereof, that specifically bind to epidermal growth factor receptor variant III (EGFRvIII) are provided. The EGFRvIII-specific humanized antibodies or antigen-binding fragments thereof may be used for the treatment of cancer.
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
A61K 51/10 - Anticorps ou immunoglobulines; Leurs fragments
Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions.
A61K 51/10 - Anticorps ou immunoglobulines; Leurs fragments
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (Canada)
NATIONAL RESEARCH COUNCIL OF CANADA (Canada)
Inventeur(s)
Samiei, Ehsan
Guenther, Axel
Veres, Teodor
Abrégé
A microfluidic flow synthesis method for collagen-based microparticles. Macro-porous fibrillar microparticles of pure collagen and composite collagen-GAG were formed, where the particle size and porosity were controlled by the flow synthesis parameters such as precursor flow rates. Using human dermal fibroblasts (hDFB) and umbilical cord derives mesenchymal stem cells (ucMSC), the capacity of the presented collagen and collagen-GAG microparticles to serve as cell culture substrates has been shown, to enable casting of tissues, forming spheroids, and as shear-thinning bioinks for bioprinting. At high packing densities, jammed collagen-based microparticles along with cells constitute a shear-thinning bioink for extrusion bioprinting applications. Bioprinted constructs exhibit a high porosity matrix due to the space between the microparticles, facilitating macromolecular transport, and cell proliferation and migration.
C12N 5/00 - Cellules non différenciées humaines, animales ou végétales, p.ex. lignées cellulaires; Tissus; Leur culture ou conservation; Milieux de culture à cet effet
A system and method are provided for optical beamforming and interferometry using digital source modulation. In one aspect, a digitally-modulated calibration signal is included in the optical target source, for use by receiving mirrors and equipment to continuously lock onto, track, and remove atmospheric and instrumental temporal distortion effects. By using this digitally-modulated calibration signal throughout the optical signal chain any variations that both it and the science/payload signal undergo can be removed, leading to lower cost optical mirrors and optical interferometers, as well as allowing for larger optical apertures
A structure for laying out electrically conductive paths over a substrate provides both AC and DC structures that can be used to improve the performance of existing structures. In an AC structure, a microstrip transmission can be reduced to half of a conventional length by having part of the signal path on the top of a substrate, and then the remaining part on the bottom of the substrate. This can be accomplished using vias, but should also be matched by moving the ground path, which is a second electrically conductive path, from the bottom of the substrate to the top so that the signal path is always opposed to a ground path. A similar structure of alternating electrical paths can be used in both solar cells and batteries, where segments of the anode of cathode can be inverted so that they maintain their opposed configuration while inverted.
H05K 1/11 - Eléments imprimés pour réaliser des connexions électriques avec ou entre des circuits imprimés
H01L 23/535 - Dispositions pour conduire le courant électrique à l'intérieur du dispositif pendant son fonctionnement, d'un composant à un autre comprenant des interconnexions internes, p.ex. structures d'interconnexions enterrées
H01L 31/04 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV]
H01M 50/533 - Connexions d’électrodes dans un boîtier de batterie caractérisées par la forme des conducteurs ou des languettes
H05K 1/16 - Circuits imprimés comprenant des composants électriques imprimés incorporés, p.ex. une résistance, un condensateur, une inductance imprimés
40.
EXPRESSION SYSTEM FOR CONSTITUTIVE OR CUMATE-INDUCIBLE EXPRESSION IN CHO CELLS
Provided are methods, expression systems, kits, and vectors for constitutive and/or cumate-inducible expression of a gene of interest in CHO cells. The expression systems and methods described herein employ CHO cells that are stably transfected with a nucleic acid molecule encoding a reverse cumate transactivator (rcTA), the expression of which is regulated by a cymene repressor (CymR), for constitutive and/or cumate-inducible expression of a gene of interest.
C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p.ex. cellules transformées par des virus
C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
C12N 15/12 - Gènes codant pour des protéines animales
C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteurs; Vecteurs; Utilisation d'hôtes pour ceux-ci; Régulation de l'expression
C12N 15/87 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p.ex. co-transformation
C12P 21/00 - Préparation de peptides ou de protéines
A coupler for coupling an RF connector to an ultrasound sensing element. The coupler includes a conductive coupler body with a first end and a second end. The first end includes a pad retaining recess with a compressible conductive pad positioned in and protruding from the pad retaining recess. The second end either includes an opening for receiving a male pin of a radio frequency (RF) connector or is shaped to be press-fitted into the female pin opening of an RF connector, to conductively connect the pin with the coupler body. A sensor connector is also disclosed.
H01R 13/631 - Moyens additionnels pour faciliter l'engagement ou la séparation des pièces de couplage, p.ex. moyens pour aligner ou guider, leviers, pression de gaz pour l'engagement uniquement
G01D 11/00 - MESURE NON SPÉCIALEMENT ADAPTÉE À UNE VARIABLE PARTICULIÈRE; DISPOSITIONS NON COUVERTES PAR UNE SEULE DES AUTRES SOUS-CLASSES POUR MESURER PLUSIEURS VARIABLES; APPAREILS COMPTEURS À TARIFS; DISPOSITIONS POUR LE TRANSFERT OU LA TRANSDUCTION DE MESURE NON SPÉCIALEMENT ADAPTÉES À UNE VARIABLE PARTICULIÈRE; MESURES OU TESTS NON PRÉVUS AILLEURS - Parties constitutives des dispositions pour la mesure qui ne sont pas spécialement adaptées à une variable particulière
H01R 13/646 - CONNEXIONS CONDUCTRICES DE L'ÉLECTRICITÉ; ASSOCIATION STRUCTURELLE DE PLUSIEURS ÉLÉMENTS DE CONNEXION ÉLECTRIQUE ISOLÉS LES UNS DES AUTRES; DISPOSITIFS DE COUPLAGE; COLLECTEURS DE COURANT - Détails de dispositifs de couplage des types couverts par les groupes ou spécialement adaptés à la haute fréquence, p.ex. structures procurant une adaptation d'impédance ou un accord de phase
H01R 24/40 - Dispositifs de couplage en deux pièces, ou l'une des pièces qui coopèrent dans ces dispositifs, caractérisés par leur structure générale ayant des contacts disposés concentriquement ou coaxialement spécialement adaptés à la haute fréquence
42.
SURROGATE DNA TO INCREASE PROTEIN PRODUCTION BY STABLY TRANSFECTED MAMMALIAN CELLS
The present disclosure relates to the use of surrogate DNA, such as salmon testis DNA or plasmid DNA, to increase protein production by stably transfected mammalian cells, such as Chinese Hamster Ovary (CHO) cells or human embryonic kidney (HEK) cells. Provided are stably transfected mammalian cells for production of proteins of interest, methods for producing proteins of interest in stably transfected mammalian cells, and compositions for stable transfection of mammalian cells to enable production of proteins of interest by the mammalian cells.
A composition for use in a photo-active device has: a charge transfer network of single walled carbon nanotubes (SWCNT) having at least 95 wt% of semiconducting single walled carbon nanotubes (sc-SWCNT) based on total weight of the SWCNT, the sc-SWCNT containing at least 30 wt% of one chiral type of sc-SWCNT based on total weight of the sc-SWCNT; and, a solution processible electron trapping material of a fullerene compound, the electron trapping material in contact with the charge transfer network of SWCNT. The composition is readily prepared from solution processible components and is highly sensitive in a narrow wavelength band. The composition is particularly useful in photoconductors and phototransistors that operate on the infrared region of the electromagnetic spectrum.
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
H01L 51/00 - Dispositifs à l'état solide qui utilisent des matériaux organiques comme partie active, ou qui utilisent comme partie active une combinaison de matériaux organiques et d'autres matériaux; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
H01L 51/48 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
H01L 51/56 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de tels dispositifs ou de leurs parties constitutives
44.
REFRACTORY LANCE ASSEMBLY AND REFRACTORY LANCE TUBE
Described are various embodiments of a refractory lance assembly and a composite refractory lance. In one embodiment, a refractory lance assembly is provided that comprises: an immersion tube having an immersion tip immersible within a melt and an extension tube coupled at an opposed end thereof to form a longitudinally extended composite tube therewith defining an optical path therein, wherein said longitudinally extended composite tube is injectable, in use, with an inert gas to form and probe an immersed melt surface. The assembly further comprises a shroud longitudinally encasing the composite tube and injectable with inert gas to mitigate fluid contamination of the composite tube and immersed melt surface.
G01N 21/71 - Systèmes dans lesquels le matériau analysé est excité de façon à ce qu'il émette de la lumière ou qu'il produise un changement de la longueur d'onde de la lumière incidente excité thermiquement
This application relates to a precursor fibre composition comprising free-radical intermediate(s) coupled to compound(s) of asphaltenes, wherein the free radical intermediate(s) is formed from the coupling of free radical(s) of at least one of acrylonitrile and acrylonitrile derivative(s). The intermediate(s) can be coupled with the compound(s) of the asphaltenes to form secondary free-radical intermediate(s), which are coupled to one another. The application also relates to asphaltene fibres produced therefrom. The precursor fibre composition is capable of being spun into green fibres, which can be thermally treated to form carbon fibres. The application also relates to a method for making a precursor fibre composition.
D01F 9/155 - Filaments de carbone; Appareils spécialement adaptés à leur fabrication par décomposition de filaments organiques à partir de brai ou de résidus de distillation à partir de brai de pétrole
46.
TWO DIMENSIONAL BENZO[4,5]IMIDAZO[2,1-A]ISOINDOLE INCORPORATED NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES
The present application provides two dimensional benzo[4,5]imidazo[2,1-a]isoindole incorporated non-fullerene electron acceptors having the structure of Formula I (I), and processes for the synthesis and manufacture thereof. Also provided are semiconductor materials, polymers, oligomers, films and membranes incorporating the non-fullerene acceptor of Formula (I), and the optoelectronic devices made therefrom.
C07D 495/22 - Composés hétérocycliques contenant dans le système condensé au moins un hétérocycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle dans lesquels le système condensé contient au moins quatre hétérocycles
C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
H01L 35/24 - Emploi d'un matériau spécifié pour les bras de la jonction utilisant des compositions organiques
A permanent magnet (PM) for use in an electric machine including at least one cavity containing a phase change material (PCM) integrated with said PM, the PCM having a phase transition temperature between about 80°C to about 200°C, and preferably a latent heat of at least 50 kJ/kg, wherein in PM, each cavity is a blind, elongated chamber extending from one side of the PM, having two smaller dimensions and a larger dimension of each cavity is oriented substantially in a same direction, wherein the PM is composed of a hard magnetic phase, a binder phase and PM having an ultimate tensile strength of at least 150 Megapascal (MPa), wherein PM is mounted on a rotor of an electric machine and is formed by cold spray additive manufacturing (CSAM)
H01F 41/02 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants
Provided herein are methylotrophic single cell protein products as a source of protein for use in a variety of methods. Also provided are animal feeds comprising the methylotrophic single cell protein products and methods of making and using the methylotrophic single cell protein products.
A23K 10/16 - Ajout de micro-organismes ou de leurs produits d’extraction, p.ex. de protéines provenant d’organismes unicellulaires, à des compositions de produits alimentaires
A23J 1/00 - Préparation des compositions à base de protéines pour l'alimentation; Ouverture des œufs par grandes quantités et séparation du jaune du blanc
A23K 20/147 - Dérivés polymériques, p.ex. peptides ou protéines
A23K 50/80 - Produits alimentaires spécialement conçus pour des animaux spécifiques pour les animaux aquatiques, p.ex. pour les poissons, les crustacés ou les mollusques
A digital clean-up oscillator and associated method are provided for cleaning jitter from a noisy clock signal, comprising receiving a reference clock oscillator signal and the noisy clock signal to be cleaned; measuring the frequency of the reference clock signal in the time domain of the noisy clock signal; filtering any frequency variations from the measured frequency of the reference clock signal on timescales shorter than a phase change interval Tau_clean over which jitter in the noisy clock signal is to be cleaned; generating a phase increment signal DDS_pinc based on the measured and filtered frequency of the reference clock signal; clocking the phase increment signal DDS_pinc with the reference clock signal for generating an output digital phase ramp signal φ_DDS(t) that tracks the frequency of the noisy clock signal with phase wander removed on timescales less than the phase change interval Tau_clean; and converting the output digital phase ramp signal φ_DDS(t) to an output jitter-cleaned time domain clock signal frequency locked to the noisy clock signal.
H03K 5/1252 - Suppression ou limitation du bruit ou des interférences
H03K 5/135 - Dispositions ayant une sortie unique et transformant les signaux d'entrée en impulsions délivrées à des intervalles de temps désirés par l'utilisation de signaux de référence de temps, p.ex. des signaux d'horloge
H03L 7/00 - Commande automatique de fréquence ou de phase; Synchronisation
50.
SYSTEM AND METHOD FOR REMOTE DIGITAL TIME TRANSFER
Methods and systems for synchronizing at least one remote local oscillator with a central local oscillator, comprising receiving a remote local oscillator signal from at least one remote local oscillator and a master local oscillator signal from the central local oscillator and in response determining a round‐trip phase measurement of temporal delay variability of the duplex real‐time link between the remote station and central station, measuring frequency vs. time of the remote local oscillator signal relative to the master oscillator, adjusting the measured frequency vs. time according to the round‐trip phase measurement to remove effects of temporal delay variability over the duplex real‐time link telemetry, digitally filtering the measured frequency to remove variations in frequency on timescales < 10x the round‐trip delay and that are known not to be intrinsically due to the remote local oscillator, generating a phase increment signal from the filtered measured frequency, receiving and adjusting the local oscillator signal according to the phase increment signal and in response generating a derived digital domain clock signal that tracks the master local oscillator signal and converting the derived digital domain clock signal to an ultra‐low phase‐noise time domain voltage clock signal.
Described herein are antibodies that specifically recognize the SARS-CoV-2 spike (S) polypeptide,compositions comprising said antibodies, uses thereof, and methods employing said antibodies. Eachantibody specifically recognizes the S1-RBD domain, S1-NTD domain, or S2 subunit of the SARS-CoV-2 spike polypeptide. Some antibodies are cross-reactive with variants of SARS-CoV-2 and othercoronavirus spike polypeptides, such as SARS-CoV S, pangolin CoV S, bat SARS-like CoV S, andcivet SARS-CoV S.
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
DPEP-1 binding agents, including antibodies, and pharmaceutical compositions containing the same are described. Also provided are methods for using and manufacturing such binding agents, antibodies and pharmaceutical compositions, as well as methods of their use for treating or preventing a disorder in a human subject in need thereof.
An electrochemical device is disclosed and may include an electrolyte composition disposed between the anode and the cathode and a water vapor barrier which may include a biodegradable material, where the water vapor barrier is disposed to prevent water vapor escaping from the electrochemical device. The water vapor barrier further may include polylactic acid or a metalized coating. The water vapor barrier further may further include multiple layers and have a water vapor transmission rate (WVTR) less than or equal to 2 wt % over 24 hours. Embodiments of the water vapor barrier may also include a polymeric biodegradable material or a metalized coating disposed onto the biodegradable material. The water vapor barrier may also include multiple layers and may have a water vapor transmission rate (WVTR) less than or equal to 1 mg per cm2 over 24 hours.
B32B 27/32 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyoléfines
H01M 50/103 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par leur forme ou leur structure physique prismatique ou rectangulaire
H01M 50/122 - Matériau composite constitué d’un mélange de matériaux organiques et inorganiques
H01M 50/124 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par le matériau ayant une structure en couches
H01M 50/126 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par le matériau ayant une structure en couches comprenant au moins trois couches
H01M 50/128 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par le matériau ayant une structure en couches comprenant au moins trois couches dont au moins deux couches de matériaux inorganiques uniquement
H01M 50/129 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par le matériau ayant une structure en couches comprenant au moins trois couches dont au moins deux couches de matériaux organiques uniquement
H01M 50/141 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie pour protéger contre les dommages causés par des facteurs externes pour protéger contre l’humidité
54.
ANTI-EGFR SINGLE DOMAIN ANTIBODIES AND THERAPEUTIC CONSTRUCTS
Herein are provided anti-EGFR single domain antibodies (sdAb) prepared by immunizing a llama with recombinant human EGFRvIII. VHH antibodies specific to EGFR were isolated. The example antibodies initially produced comprise CDR1, CDR2, and CDR3 sequences corresponding, respectively to SEQ NOs: 1-3, 4-6, 7-9, 10-12, 13-15, 16-18, 19-21, 22-24, 25-27, 28-30, 31-33, 34-36, 37-39, 40-42, 43-45, and 46-48; and related sequences, including humanized variants. Also provided are multivalent antibodies comprising any one of the sdAbs, including bispecific T-cell engagers, bispecific killer cell engagers (BiKEs), and trispecific killer cell engagers (TriKEs). Also described are chimeric antigen receptors (CARs) for CAR-T therapy comprising any one of the aforementioned sdAbs. Uses of these molecules in the treatment of cancer are also described, in particularly EGFR-high cancers. Hinge lengths may be selected to achieve desired activities, such as high activity or high selectivity for target vs. non-target cells.
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
C07K 14/705 - Récepteurs; Antigènes de surface cellulaire; Déterminants de surface cellulaire
C07K 16/18 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
C07K 16/30 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire provenant de cellules de tumeurs
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer material comprising at least one thermoplastic polymer, and a plurality of piezoelectric covalently bonded to the at least one thermoplastic polymer and dispersed in at least a portion of the polymer material. The compositions are extrudable and may be pre-formed into a form factor suitable for extrusion. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles non-covalently interacting with at least a portion of a polymer material via π-π bonding, hydrogen bonding, electrostatic interactions stronger than van der Waals interactions, or any combination thereof. The piezoelectric particles may be dispersed in the polymer material and remain substantially non-agglomerated when combined with the polymer material. The polymer material may comprise at least one thermoplastic polymer, optionally further including a polymer precursor. The compositions may define an extrudable material that is a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles and a polymer material comprising at least one thermoplastic polymer and at least one thermally curable polymer precursor. At a sufficient temperature, the at least one thermally curable polymer precursor may undergo a reaction, optionally also undergoing a reaction with the piezoelectric particles, and form an at least partially cured printed part. The piezoelectric particles may be mixed with the polymer material and remain substantially non-agglomerated when combined with the polymer material. The compositions may define a form factor such as a composite filament, a composite pellet, or an extrudable composite paste, which may be utilized in forming printed part by extrusion, layer-by-layer deposition, and thermal curing.
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles and a polymer material comprising at least one thermoplastic polymer and at least one photocurable polymer precursor. The at least one photocurable polymer precursor may undergo a reaction in the presence of electromagnetic radiation, optionally undergoing a reaction with the piezoelectric particles, in the course of forming the printed part. The piezoelectric particles may be mixed with the polymer material and remain substantially non-agglomerated when combined with the polymer material. The compositions may define a form factor such as a composite filament, a composite pellet, or an extrudable composite paste, which may be utilized in forming printed parts by extrusion and layer-by-layer deposition, followed by curing.
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
B29C 64/165 - Procédés de fabrication additive utilisant une combinaison de matériaux solides et liquides, p.ex. une poudre avec liaison sélective par liant liquide, catalyseur, inhibiteur ou absorbeur d’énergie
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer material comprising at least one thermoplastic polymer, at least one polymer precursor, or any combination thereof, and a plurality of piezoelectric particles dispersed in at least a portion of the polymer material. The piezoelectric particles may interact non-covalently with at least a portion of the polymer material, be covalently bonded to at least a portion of the polymer material, and/or be reactive with at least a portion of the polymer material. The compositions may be extrudable and formable into a self-standing three-dimensional structure upon being extruded. Additive manufacturing processes may comprise forming a printed part by depositing the compositions layer-by-layer.
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions that are extrudable and comprise a plurality of piezoelectric particles and a plurality of carbon nanomaterials dispersed in at least a portion of a polymer material. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer material. The polymer material may comprise at least one thermoplastic polymer, optionally further containing at least one polymer precursor. The compositions may define an extrudable material that is a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles dispersed in a continuous polymer matrix comprising a first polymer material and a sacrificial material that are immiscible with each other. The sacrificial material, which may comprise a second polymer material, may be removable from the first polymer material under specified conditions. The piezoelectric particles may remain substantially non-agglomerated when combined with the continuous polymer matrix. The continuous polymer matrix may be treated to remove the sacrificial material to introduce a plurality of pores. The compositions may have a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes may comprise forming a printed part by depositing the compositions layer-by-layer.
H01L 41/27 - Fabrication de dispositifs piézo-électriques ou électrostrictifs multicouches ou de leurs parties constitutives, p.ex. en empilant des corps piézo-électriques et des électrodes
H01L 41/47 - Procédés ou appareils spécialement adaptés à l'assemblage, la fabrication ou au traitement de dispositifs magnétostrictifs, ou de leurs parties constitutives
62.
PIEZOELECTRIC COMPOSITES HAVING IMMISCIBLE POLYMER MATERIALS AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer matrix comprising a first polymer material and a second polymer material that are immiscible with each other, and a plurality of piezoelectric particles located in at least a portion of the polymer matrix. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer matrix. The compositions may define an extrudable material that is a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles dispersed in at least a portion of a polymer matrix comprising first polymer material and a sacrificial material, the sacrificial material being removable from the polymer matrix to define a plurality of pores in the polymer matrix. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer matrix. The sacrificial material may comprise a second polymer material. The compositions may define a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes may comprise forming a printed part by depositing the compositions layer-by-layer and introducing porosity therein
H01L 41/27 - Fabrication de dispositifs piézo-électriques ou électrostrictifs multicouches ou de leurs parties constitutives, p.ex. en empilant des corps piézo-électriques et des électrodes
H01L 41/47 - Procédés ou appareils spécialement adaptés à l'assemblage, la fabrication ou au traitement de dispositifs magnétostrictifs, ou de leurs parties constitutives
64.
PIEZOELECTRIC COMPOSITES HAVING LOCALIZED PIEZOELECTRIC PARTICLES AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer matrix comprising a first polymer material and a second polymer material that are immiscible with each other, and a plurality of piezoelectric particles substantially localized in one of the first polymer material or the second polymer material. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer matrix. The compositions may define a form factor such as a composite filament, a composite pellet, or an extrudable composite paste. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
A system for the online sorting of ore samples based on mineralogy analysis includes a conveyor moving a stream of the ore samples along a conveying path, a LIBS module, a height measuring device, a focus controller and an airflow system. The LIBS module projects a LIBS laser beam along an optical path focused on an analysis spot of dimensions of the order of one or a few mineral components of the ore samples, and collects a returning LIBS light signal. The height measuring device and focus controller collaborate to adjust in real-time the focus of the LIBS laser beam to move the analysis spot perpendicularly to the conveyor according to a height of the ore samples crossing the optical path. The air flow system moves particles away from the optical path. A processing unit performs the mineralogy analysis of the ore sample based on the LIBS light signal.
G01N 21/71 - Systèmes dans lesquels le matériau analysé est excité de façon à ce qu'il émette de la lumière ou qu'il produise un changement de la longueur d'onde de la lumière incidente excité thermiquement
B07B 13/14 - Classement ou triage des matériaux solides par voie sèche non prévu ailleurs; Triage autrement que par des dispositifs commandés indirectement - Parties constitutives ou accessoires
The present invention provides a method and system to correctly sample, at a central location, a signal at a second clock frequency from a remote antenna when the signal is at a first clock frequency. The present invention provides an improved method of incoherent clocking to correctly sample a signal from a remote antenna at a clock frequency of a central location, such as a central site of a radio telescope array. The signal contains a "tracer" which is related to the frequency of the remote antenna. The tracer phase is written into a dual-port memory at the first clock frequency and then read from the memory at the second clock frequency. The tracer phase is transferred across digital clock domains using Gray-doe methods so that phase coding errors do not occur.
Centrifugal microfluidic fractionation is facilitated by off-chip pressurized fluid control applied at ports of a centrifugal microfluidic chip during centrifugation. The off-chip control is leveraged to align a desired fraction of the fractionated sample in a column on the chip to an extraction channel for greater precision extraction. Higher density or lower density media can be used to displace the fractionated sample axis-proximally or axis-distally, respectively. Automation by pixel-based strobed imaging of the chip with image analysis can reduce human intervention in fractionation assaying.
The present invention relates, in general, to polypeptides capable of neutralizing SARS-CoV-2 and providing ACE2 enzymatic activity, and uses of these polypeptides for treating disorders related coronaviral infections (COVID-19) and the accompanying acute respiratory distress syndrome (ARDS) and major organ injuries, and methods of making such molecules.
The disclosure pertains to tightly regulated inducible expression systems useful for the inducible production of one or more RNAs or proteins of interest, including the production of biologics such as recombinant proteins, vaccines, or viral vectors. Also provided are cell lines and kits useful for the production of said RNAs or proteins, as well as methods for making said cell lines and methods for inducing production of said RNAs or proteins.
Provided is an adjuvant composition comprising a glycoarchaeol and at least one immunostimulantselected from a Toll-like receptor (TLR) agonist and a saponin. The glycoarchaeol and/orimmunostimulant may be present as a pharmaceutically acceptable salt. The adjuvant compositionmay be comprised together with an antigen in an immunogenic composition, such as a vaccinecomposition, which may be for use to induce an immune response in a subject. Further provided isuse of the immunogenic composition to induce an immune response in a subject, particularly animmune response that comprises both a cell-mediated response and a humoral response.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p.ex. par les adjuvants chimiques
A system for forming an object having a three-dimensional structure, the system comprising: a container for providing a photo-curable material to be polymerized; a rotatable stage for supporting the container; a light source for providing light rays having at least one light pattern to be guided into the container via an optical assembly; a processing unit for determining the light source's degree of non-telecentricity, and determining an optimally pre-distorted set of the at least one light pattern based on at least the photo-curable material's refractive index; correcting at least one distortion of the light rays caused by refraction at the container interface and/or correcting at least one distortion of the light rays caused by non-telecentricity; and whereby the correction of the at least one distortion of the light rays is performed without altering the calibration of the optical assembly.
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
The present invention provides an efficient quantum memory for storing a quantum state of light, such as a photon, for a temporary period of time in a fibre-integrated optical cavity and then recall the quantum state of light and quantum information at a later time with a high probability of success. The present invention uses a nonlinear optical switching mechanism to modify at least one property of the quantum light, or cavity, to trap the quantum light in the optical cavity. Subsequent application of the nonlinear optical switching mechanism switches at least one property of the stored quantum light, or cavity, to release the quantum light from the optical cavity. The present invention also provides quasi-deterministic single-photon generation by temporal multiplexing of a photon pair source integrated within the cavity.
G11C 13/04 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage non couverts par les groupes , ou utilisant des éléments optiques
G02B 6/10 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p.ex. couplage ou commande de qubit
74.
LOW SCATTERING LOSS HIGH TEMPERATURE STABLE FIBER BRAGG GRATING SENSOR BASED ON MICROPORE FORMATION AND METHOD FOR PRODUCING SAME
A method and apparatus for inscribing a high-temperature stable Bragg grating in an optical waveguide, comprising the steps of: providing the optical waveguide; providing electromagnetic radiation from an ultrashort pulse duration laser, wherein the wavelength of the electromagnetic radiation has a characteristic wavelength in the wavelength range from 150 nanometers (nm) to 2.0 micrometers (μm); providing cylindrical focusing optics; providing a diffractive optical element that when exposed to the focused ultrashort laser pulse, creates an interference pattern on the optical waveguide, wherein the irradiation step comprises irradiating a surface of the diffractive optical element with the focused electromagnetic radiation, the electromagnetic radiation incident on the optical waveguide, from the diffractive optical element, being sufficiently intensive to cause permanent (Type II) change in the index of refraction within multiple Bragg grating planes in the core of the optical waveguide resulting from at least one micropore.
The use of an unctuous sealing material (high viscosity liquid bordering on, or having, solid behavior at low shear forces) for sealing open pore, highly crushable suction cups allows for increased surface conformation for fast secure vacuum gripping, and maintenance of the pressure differential with lower energy in view of the seal.Furthermore, fast grasping is demonstrated if the unctuous sealing material protrudes from the lip.
B05D 5/10 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface adhésive
B25J 15/06 - Têtes de préhension avec moyens de retenue magnétiques ou fonctionnant par succion
B66C 1/02 - Eléments ou dispositifs de prise de la charge adjoints aux mécanismes de levage, de descente ou de halage, ou adaptés pour être utilisés avec ces mécanismes et transmettant les efforts à des articles ou à des groupes d'articles par succion
F16B 47/00 - Ventouses pour accrochage; Moyens équivalents utilisant des adhésifs
There is provided a biosensor for detecting water contaminants. The biosensor has a microbial fuel cell compartment, having (i) at least one opening to allow water into and out of the microbial fuel cell compartment, (ii) an anode comprising electroactive microorganisms, and (iii) a cathode. The anode is electrically and physically separated from the cathode. The anode is anaerobic and comprises electroactive microorganisms. The cathode is aerobic. The biosensor has a storage compartment housing a biodegradable carbon source to supply the biodegradable carbon source to the electroactive microorganisms; an electric impedance load; an electric switch forming an intermittent connection between the microbial fuel cell compartment and the electric impedance load; an electric sensor; and a control system coupled to the electric switch and the electric sensor, receiving a measurement from the electric sensor, and outputting an indication signaling the presence or absence of the water contaminants based on the measurement.
A device and method of fabricating a device having a plurality of depletion-mode high-electron-mobility transistors (HEMTs) on a single wafer are disclosed. The method of fabrication involves providing semiconductor layers capable of sustaining a two-dimensional electron sheet to enable electrical current to flow through the HEMT, forming a series of trenches and fins in the semiconductor layers over an active area of the semiconductor layers on which a gate contact terminal is to be set down, the fins of respective HEMTs having different widths resulting in different voltage thresholds for the respective depletion-mode HEMTs.
H01L 21/18 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives les dispositifs présentant au moins une barrière de potentiel ou une barrière de surface, p.ex. une jonction PN, une région d'appauvrissement, ou une région de concentration de porteurs de charges les dispositifs ayant des corps semi-conducteurs comprenant des éléments du groupe IV de la classification périodique, ou des composés AIIIBV, avec ou sans impuretés, p.ex. des matériaux de dopage
H01L 29/778 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à deux dimensions, p.ex. transistors à effet de champ à haute mobilité électronique HEMT
78.
MONOLITHIC INTEGRATION OF ENHANCEMENT-MODE AND DEPLETION-MODE GALIUM NITRIDE HIGH ELECTRON MOBILITY TRANSISTORS
A device and method of fabricating a device having depletion-mode and enhancement-mode high-electron-mobility transistors (HEMTs) on a single wafer are disclosed. The method of fabrication involves providing semiconductor layers capable of sustaining a two-dimensional electron sheet to enable electrical current to flow through the HEMT, forming a series of trenches and fins in the semiconductor layers over an active area of the semiconductor layers on which a gate contact terminal is to be set down, the fins of respective HEMTs having different widths resulting in different voltage thresholds for the respective depletion-mode HEMTs.
H01L 21/77 - Fabrication ou traitement de dispositifs consistant en une pluralité de composants à l'état solide ou de circuits intégrés formés dans ou sur un substrat commun
H01L 29/778 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à deux dimensions, p.ex. transistors à effet de champ à haute mobilité électronique HEMT
A method and apparatus are provided for effecting an RFID-based finger input sensing system using a transmission line connected to at least two RFID tags, by analyzing a plurality of features relating to the number of spikes in the derivatives of the RSS, timing of maximum RSS and the spikes of the RSS derivatives, relative RSS magnitude between the at least two RFID tags, and increase/decrease trend of the RSS, thereby eliminating the need for calibration and training.
G06F 3/046 - Numériseurs, p.ex. pour des écrans ou des pavés tactiles, caractérisés par les moyens de transduction par des moyens électromagnétiques
G06F 3/0362 - Dispositifs de pointage déplacés ou positionnés par l'utilisateur; Leurs accessoires avec détection des translations ou des rotations unidimensionnelles [1D] d’une partie agissante du dispositif de pointage, p.ex. molettes de défilement, curseurs, boutons, rouleaux ou bandes
G06K 7/10 - Méthodes ou dispositions pour la lecture de supports d'enregistrement par radiation corpusculaire
80.
DNA CONSTRUCT FOR STABLY PRODUCING EMPTY CAPSIDS OF THE FOOT-AND-MOUTH DISEASE VIRUS IN MAMMALIAN CELLS; PROCESSES, USES, AND COMPOSITIONS THEREOF
INSTITUTO NACIONAL DE TECNOLOGIA AGROPECUARIA (Argentine)
NATIONAL RESEARCH COUNCIL OF CANADA (Canada)
Inventeur(s)
Mignaqui, Ana Clara
Wigodorovitz, Andres
Durocher, Yves
Abrégé
The present invention refers to methods and compositions for increasing the production of large amounts of empty capsids of the foot-and-mouth disease virus (FMDV) in a stable manner in mammalian cells by regulating the expression of FMDV 3C protease. The instant methods and compositions are based on the fact that a decreased expression of 3C protease results in a reduced cell toxicity and an increased synthesis of viral capsid proteins, as well as production of recombinant empty capsids. The invention provides recombinant plasmids that direct the expression of P1, 3C, and the use of said plasmids for producing new stable cell lines capable of generating high titers of FMDV empty capsids. The invention provides methods for regulating the expression of the FMDV 3C protease gene at a transcriptional and translational level in order to achieve the required process level of 3C protease for the selection process, as well as the production process.
Cellulose particles treated with a bio-based surfactant can be compounded into a polymer composite having improved mechanical properties, such as tensile strength and/or tensile modulus. Treatment can be integrated into an industrial scale continuous cellulose particle production process, and the process provides one or more of reduced environmental impact, reduced energy consumption, reduced chemical consumption, reduced water consumption, reduced processing/operational cost, reduced capital investment, increased output, improved fiber dispersion in the polymer matrix and improved thermal degradation properties of the composite.
C08L 23/00 - Compositions contenant des homopolymères ou des copolymères d'hydrocarbures aliphatiques non saturés ne possédant qu'une seule liaison double carbone-carbone; Compositions contenant des dérivés de tels polymères
D06M 13/00 - Traitement des fibres, fils, filés, tissus ou articles fibreux faits de ces matières, avec des composés organiques non macromoléculaires; Un tel traitement combiné avec un traitement mécanique
D21C 1/00 - Traitement préalable des matériaux finement divisés avant la cuisson
D21C 1/10 - Méthodes physiques pour faciliter l'imprégnation
82.
SEMICONDUCTOR DEVICES WITH GRADED INTERFACE REGIONS
An example semiconductor device includes: a first layer comprising a first semiconductor material; a second layer comprising a second semiconductor material; and an interface region disposed between the first layer and the second layer and corresponding to an expected depletion region of an interface between the first semiconductor material and the second semiconductor material, the interface region comprising a gradation from the first semiconductor material to the second semiconductor material; and wherein the interface region is configured to reduce Shockley-Read-Hall recombination in the semiconductor device.
H01L 29/36 - Corps semi-conducteurs caractérisés par la concentration ou la distribution des impuretés
H01L 29/20 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIIIBV
H01L 31/065 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type à bande interdite graduelle
H01L 31/0296 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIIBVI, p.ex. CdS, ZnS, HgCdTe
83.
CORRUGATED BURIED HETEROSTRUCTURE LASER AND METHOD FOR FABRICATING THE SAME
There is provided a method for fabricating a corrugated buried heterostructure laser, including patterning a dielectric layer coating a substrate having a <0-11> direction to obtain a hollow corrugated structure. The hollow corrugated structure includes a central portion and regularly spaced-apart tabs laterally extending from the central portion and aligned with the <0-11> direction. The method also includes, in a single metal organic chemical vapour deposition run, forming an active region in the hollow corrugated structure to obtain the corrugated buried heterostructure laser. The single run combines selective area growth, p-dopant diffusion and etching techniques. There is also provided a corrugated buried heterostructure laser including a substrate having a <0-11> direction, a corrugated structure defined in the substrate and including a central portion and regularly spaced-apart tabs laterally extending from the central portion and aligned with the <0-11> direction, and an active region grown in the corrugated structure.
H01S 5/12 - Structure ou forme du résonateur optique le résonateur ayant une structure périodique, p.ex. dans des lasers à rétroaction répartie [lasers DFB]
H01S 5/32 - Structure ou forme de la région active; Matériaux pour la région active comprenant des jonctions PN, p.ex. hétérostructures ou doubles hétérostructures
84.
REALIZATION OF THE PASCAL FROM THE BOLTZMANN CONSTANT USING MASS COMPARISON OF ARTIFACTS IN VACUUM AND GAS
The present disclosure relates to methods and systems for realization of a reference pressure as well as calibration of devices under test. The techniques leverage the measurement of buoyancy artifacts under vacuum and pressure conditions, and the use of gas law equations and related variables to obtain low uncertainty reference values for pressure among others. The techniques can include measuring an absolute mass difference of buoyancy artifacts under vacuum; measuring effective masses of the buoyancy artifacts under a gas pressure condition, and determining an effective mass difference between the buoyancy artifacts; and determining a low-uncertainty pressure based on the absolute mass difference, effective mass difference, Boltzmann constant, volume difference, molecular weight of the gas at pressure, and temperature of the measurements.
G01L 21/02 - Indicateurs de vide ayant une chambre de compression dans laquelle le gaz dont on doit mesurer la pression est comprimé
G01G 17/04 - Appareils ou méthodes pour peser un produit ayant une forme ou des propriétés particulières pour peser des fluides, p.ex. des gaz, des produits pâteux
G01K 11/00 - Mesure de la température basée sur les variations physiques ou chimiques, n'entrant pas dans les groupes , , ou
G01L 27/00 - Test ou étalonnage des appareils pour la mesure de la pression des fluides
85.
ELECTRIC MACHINES WITH ENHANCED ELECTROMAGNETIC INTERACTION
An electrical machine, which may be a motor and/or a generator has a rotor mounted to rotate about an axis. A plurality of magnetic poles are spaced circumferentially around the rotor in the bore. The rotor comprises a shell shaped to provide a toroidal bore centered on the axis. A slit extends circumferentially around the rotor. The slit penetrates through the shell into the bore. The electrical machine also includes a stator that is supported in the bore by one or more supports extending through the slit of the rotor. The stator carries plural windings that are spaced apart around the bore.
H02K 1/16 - Noyaux statoriques à encoches pour enroulements
H02K 1/22 - Parties tournantes du circuit magnétique
H02K 5/20 - Enveloppes ou enceintes caractérisées par leur configuration, leur forme ou leur construction avec des canaux ou des conduits pour la circulation d'un agent de refroidissement
86.
BURIED HETEROSTRUCTURE SEMICONDUCTOR LASER AND METHOD OF MANUFACTURE
A heterostructure laser is provided comprising an epitaxially grown substrate of first dopant type, an active region and layer of second dopant type, a narrow mesa having less than 20% open area and a side wall slope of less than 85 degrees, wherein said narrow mesa is etched through the active region and layer of second dopant type using in-situ MOCVD, a plurality of current blocking layers, an overclad layer and a contact layer of second dopant type, and an isolation mesa incorporating the narrow mesa, wherein the isolation mesa is etched through the active region, layer of second dopant type and plurality of current blocking layers and wherein the plurality of current blocking layers is grown without exposure to oxygen.
H01S 5/32 - Structure ou forme de la région active; Matériaux pour la région active comprenant des jonctions PN, p.ex. hétérostructures ou doubles hétérostructures
H01L 21/205 - Dépôt de matériaux semi-conducteurs sur un substrat, p.ex. croissance épitaxiale en utilisant la réduction ou la décomposition d'un composé gazeux donnant un condensat solide, c. à d. un dépôt chimique
87.
ULTRASONIC STRUCTURAL HEALTH MONITORING DEVICE, SYSTEM AND METHOD
Described are various embodiments of an ultrasonic structural health monitoring device, system and method. In one embodiment, an ultrasonic structural health monitoring device is described to monitor a structure. The device comprises a bottom electrode disposable on the structure; a piezoelectric medium disposed on the bottom electrode; a top electrode disposed on the piezoelectric medium; an acoustic insulation layer; and a connector to bring electrical excitation for the piezoelectric medium and to collect a generated electric response therefrom representative of structural health.
G01S 17/88 - Systèmes lidar, spécialement adaptés pour des applications spécifiques
G01S 7/523 - DÉTERMINATION DE LA DIRECTION PAR RADIO; RADIO-NAVIGATION; DÉTERMINATION DE LA DISTANCE OU DE LA VITESSE EN UTILISANT DES ONDES RADIO; LOCALISATION OU DÉTECTION DE LA PRÉSENCE EN UTILISANT LA RÉFLEXION OU LA RERADIATION D'ONDES RADIO; DISPOSITIONS ANALOGUES UTILISANT D'AUTRES ONDES - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe - Détails de systèmes à impulsions
88.
MESA AVALANCHE PHOTODIODE WITH SIDEWALL PASSIVATION
H01L 31/107 - Dispositifs sensibles au rayonnement infrarouge, visible ou ultraviolet caractérisés par une seule barrière de potentiel ou de surface la barrière de potentiel fonctionnant en régime d'avalanche, p.ex. photodiode à avalanche
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
89.
PIEZOCERAMIC PASTES WITH HIGH CERAMIC CONTENT AND METHOD FOR PRINTING SAME
The present disclosure is directed towards a formulation for piezoelectric materials. The formulation may be printed including 2D or 3D printing. The formulation contains ceramic particles, a sol-gel, a high boiling point solvent and a binder.
B29C 64/165 - Procédés de fabrication additive utilisant une combinaison de matériaux solides et liquides, p.ex. une poudre avec liaison sélective par liant liquide, catalyseur, inhibiteur ou absorbeur d’énergie
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
C08L 29/04 - Alcool polyvinylique; Homopolymères ou copolymères d'esters partiellement hydrolysés d'alcools non saturés avec des acides carboxyliques saturés
C08L 33/02 - Homopolymères ou copolymères des acides; Leurs sels métalliques ou d'ammonium
Apparatus and Method are disclosed for a data conversion apparatus for converting an electrical signal between an analogue signal and a digital signal of interest. The data conversion apparatus comprises a data converter array comprising one or more converters each for receiving a copy of an analogue electrical input signal. Each of the one or more converters are clocked at a different respective clock frequency. The data conversion apparatus additionally comprises a re-sampler for re-sampling the output of each of said one or more converters to a common clock frequency to produce a re sampled output. Each of the re-sampled outputs being correlated or compared with a reference sequence to provide the information to align the re-sampled outputs in time in the re-sampler; and each of the re-sampled outputs are added to produce the digital signal of interest.
The present disclosure relates to laminated armor materials for enhanced ballistic protection. In particular, the present disclosure relates to laminated armor materials comprising first and second armor materials and a laminated adhesive layer comprising nanomaterial fillers.
F41H 5/04 - Structure des plaques composées de plus d'une couche
B32B 18/00 - Produits stratifiés composés essentiellement de céramiques, p.ex. de produits réfractaires
B32B 27/08 - Produits stratifiés composés essentiellement de résine synthétique comme seul composant ou composant principal d'une couche adjacente à une autre couche d'une substance spécifique d'une résine synthétique d'une sorte différente
B32B 27/20 - Produits stratifiés composés essentiellement de résine synthétique caractérisée par l'emploi d'additifs particuliers utilisant des charges, des pigments, des agents thixotropiques
B32B 27/34 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyamides
B32B 27/40 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyuréthanes
92.
ANTI-CD22 SINGLE DOMAIN ANTIBODIES AND THERAPEUTIC CONSTRUCTS
Herein are provided anti-CD22 single domain antibodies (sdAb) prepared by immunizing a llama with the extracellular domain of the predominant human CD22 isoform. By constructing a library of the heavy chain repertoire generated, VHH antibodies specific to the immunogen were isolated. The 27 example antibodies initially produced comprise CDR1, CDR2, and CDR3 sequences corresponding, respectively to SEQNOs: 1-3, 4-6, 7-9, 10-12, 13-15, 16- 18, 19-21, 22-24, 25-27, 28-30, 31-33, 34-36, 37-39, 40-42, 43-45, 46-48, 49-51, 52-54, 55- 57, 58-60, 61-63, 64-66, 67-69, 70-72, 73-75, 75-78, and 79-81; and related sequences. Also provided are multivalent antibodies comprising any one of the sdAbs, including bispecific T-cell engagers, bispecific killer cell engagers (BiKEs), and trispecific killer cell engagers (TriKEs). Also described are chimeric antigen receptors (CARs) for CAR-T therapy comprising any one of the aforementioned sdAbs. Uses of these molecules in the treatment of cancer are also described.
C07K 16/22 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des facteurs de croissance
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
A laser comprising a narrow linewidth, comprising: a grating along a laser cavity; a laser waveguide having a plurality of waveguide sections corresponding to a plurality of grating sections, each of the plurality of waveguide sections having a ridge/mesa width for detuning the grating in each of the plurality of grating sections; and a plurality of contact electrodes contacting each of the plurality of waveguide sections, the plurality of contact electrodes for applying a different current to each of the plurality of waveguide sections to enable active feedback noise suppression.
H01S 5/062 - Dispositions pour commander les paramètres de sortie du laser, p.ex. en agissant sur le milieu actif en faisant varier le potentiel des électrodes
H01S 5/0687 - Stabilisation de la fréquence du laser
94.
COATED SUBSTRATES AND METHODS FOR THE PREPARATION THEREOF
The present application relates to methods of preparing a coated substrate and coated substrates which can be optionally prepared from such methods. The methods comprise depositing on the substrate a single abrasion resistant layer by magnetron sputtering or depositing on the substrate a dual layer comprising a first abrasion resistant layer deposited by magnetron sputtering and a second abrasion resistant layer deposited by plasma-enhanced chemical vapor deposition.
C23C 14/06 - Revêtement par évaporation sous vide, pulvérisation cathodique ou implantation d'ions du matériau composant le revêtement caractérisé par le matériau de revêtement
C23C 16/513 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c. à d. procédés de dépôt chimique en phase vapeur (CVD) caractérisé par le procédé de revêtement au moyen de décharges électriques utilisant des jets de plasma
C23C 28/00 - Revêtement pour obtenir au moins deux couches superposées, soit par des procédés non prévus dans un seul des groupes principaux , soit par des combinaisons de procédés prévus dans les sous-classes et
An interface device for performing off-chip coupling in optical waveguides includes an optical waveguide core for propagating light of a particular wavelength or a plurality of wavelengths and an array of radiative elements configured to change the propagation direction of the light. The optical waveguide core is configured to control the effective refractive index of the propagation mode of the light. The device can thus serve as an optical antenna for coupling between a waveguide mode and a free-space propagating beam or a plurality of free-space propagating beams in an arrayed configuration.
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
G02B 6/124 - Lentilles géodésiques ou réseaux intégrés
G02B 6/34 - Moyens de couplage optique utilisant des prismes ou des réseaux
H01S 5/02255 - Découplage de lumière utilisant des éléments de déviation de faisceaux lumineux
An antenna device for performing off-chip light coupling comprising an array of radiating elements whose thickness is larger than λ/2, the radiating elements being chosen such that the length of the array is smaller than 10 λ, where λ is the wavelength of light in the material chosen for the radiating elements. An advantage of this method is that, unlike in conventional waveguide grating antenna, by reducing the number of the radiating elements in the array, the dependence of the off-chip emission angle on the wavelength of light can be greatly reduced. Another advantage is that by using thick radiating elements the antenna efficiency can be greatly enhanced, thereby compensating for the reduced efficiency occurring as a consequence of using only a small number of radiating elements in the array.
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
G02B 6/124 - Lentilles géodésiques ou réseaux intégrés
G02B 6/34 - Moyens de couplage optique utilisant des prismes ou des réseaux
H01S 5/02251 - Découplage de lumière utilisant des fibres optiques
A method of monitoring both liner wear and charge impact in an industrial mill uses a sensor mounted on an elongated element deployed through a shell into a liner of the mill. The elongated element wears at a same rate as the liner under conditions within the shell. Liner wear is related to a reduction in length of the elongated element as measured by travel time of an ultrasound wave, while location and strength of charge impact is related to change in amplitude of vibrations caused by the charge impact. Liner wear measurement can be improved by using shear ultrasound waves instead of conventional longitudinal ultrasound waves. A mill monitoring apparatus has a means for acquiring ultrasonic waves and audible sound waves using the same digitizer; a means for determining the angular position of the monitoring apparatus; and a means for supplying electric power to the apparatus.
G01N 29/14 - Recherche ou analyse des matériaux par l'emploi d'ondes ultrasonores, sonores ou infrasonores; Visualisation de l'intérieur d'objets par transmission d'ondes ultrasonores ou sonores à travers l'objet utilisant des techniques d'émission acoustique
G01S 15/88 - Systèmes sonar, spécialement adaptés à des applications spécifiques
G01B 17/00 - Dispositions pour la mesure caractérisées par l'utilisation de vibrations infrasonores, sonores ou ultrasonores
G01S 7/536 - Extraction des signaux d'écho désirés
A computer-implemented method for detecting attribute value pairs from corpus data using a computer comprising a processor and a computer readable medium comprising instructions executable by the processor to at least: receive the corpus data comprising at least one pair; detect a layout template of the at least one pair; measure the merit of the layout template by determining at least one of (a) relative magnitudes of content probabilities based on a probability of the contents of an attribute cell and a probability of a corresponding value cell, (b) the validity of a name-value pair, or (c) the pointwise mutual information of a frequency matrix M corresponding to a sparse vector capturing context information of a word; and output detected attribute value pairs.
G06F 17/00 - TRAITEMENT ÉLECTRIQUE DE DONNÉES NUMÉRIQUES Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des fonctions spécifiques
G06F 16/20 - Recherche d’informations; Structures de bases de données à cet effet; Structures de systèmes de fichiers à cet effet de données structurées, p.ex. de données relationnelles
G06F 16/28 - Bases de données caractérisées par leurs modèles, p.ex. des modèles relationnels ou objet
G06F 17/18 - Opérations mathématiques complexes pour l'évaluation de données statistiques
99.
A METHOD FOR FABRICATING CONDUCTIVE YARNS AND FABRICS AT ROOM TEMPERATURE
A method of fabricating a conductive yarn comprising a plurality of filaments, the method comprising the steps of: (a) applying a reducing agent solution to the treated surface; and (b) applying a metal ion solution to the treated at least one of the plurality of filaments. The method comprising a further step of treating the surface of the at least one of the plurality of filaments with a hydrophilic agent before performing steps (a) and (b).
H01B 1/22 - Matériau conducteur dispersé dans un matériau organique non conducteur le matériau conducteur comportant des métaux ou des alliages
D06M 11/83 - Traitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexes; Un tel traitement combiné avec un traitement mécanique, p.ex. mercerisage avec des composés libérant des métaux, p.ex. des métaux-carbonyles; Réduction de composés métalliques sur des textiles
H05K 3/10 - Appareils ou procédés pour la fabrication de circuits imprimés dans lesquels le matériau conducteur est appliqué au support isolant de manière à former le parcours conducteur recherché
100.
SYNCHRONOUS RECTIFICATION TO IMPROVE EFFICIENCY OF ELECTRICITY CONVERSION FOR HARVESTING ENERGY FROM LOW VOLTAGE SOURCES
A DC-DC converter for converting a low voltage DC input to a higher voltage DC output, the DC-DC converter comprising: an oscillator comprising a first relatively voltage sensitive and relatively low power transistor and a second relatively voltage insensitive and relatively high power transistor, the oscillator producing an AC signal from the low voltage DC input; a first transformer for converting the AC signal produced by the oscillator to a higher voltage AC signal; an autonomous, synchronous voltage-doubling rectification circuit for converting the higher voltage AC signal to the higher voltage DC output, wherein the autonomous, synchronous voltage-doubling rectification circuit comprises a second transformer, a first shunt switch and a second shunt switch; and wherein current through the second transformer controls the synchronous rectification.
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
brevets
