System/Method/Device for labelling images in an automated manner to satisfy a performance of a different algorithm and then applying active learning to learn a deep learning model which would enable ‘real-time’ operation of quality assessment and with high accuracy.
G06T 7/246 - Analyse du mouvement utilisant des procédés basés sur les caractéristiques, p.ex. le suivi des coins ou des segments
G06V 10/74 - Appariement de motifs d’image ou de vidéo; Mesures de proximité dans les espaces de caractéristiques
G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”
G06V 10/776 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source Évaluation des performances
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 10/94 - Architectures logicielles ou matérielles spécialement adaptées à la compréhension d’images ou de vidéos
A system including: a contact element for fixing the relative geometric position and orientation of a patient's eye with respect to a laser applicator and a lens element for insertion into the contact element. The contact element receives the lens element at a predetermined position. The lens element has an eye surface and the lens element has a projection element that engages with one or several holding elements from below for fastening the lens element in the contact element by a snap-action connection. The lens element presents a lens contact surface on a lower side of a projection element. The at least one projection element engages the at least one holding element. The lens contact surface is pressed against an elastic compensation element arranged on a fastening surface of the contact element and serving to reduce the forces acting on the lens element by the at least one holding element.
A computer-implemented method for determining the refractive power of an intraocular lens includes providing a physical model for determining refractive power and training a machine learning system with clinical ophthalmological training data and associated desired results to form a learning model for determining the refractive power. A loss function for training includes: a first component taking into account clinical ophthalmological training data and associated and desired results and a second component taking into account limitations of the physical model wherein a loss function component value is greater the further a predicted value of the refractive power during the training is from results of the physical model with the same clinical ophthalmological training data as input values. Moreover, the method includes providing ophthalmological data of a patient and predicting the refractive power of the intraocular lens to be used by means of the trained machine learning system.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
A method and a system for calibrating cameras of a multichannel medical visualization system, including capturing a capturing region respectively imaged via channels of the multichannel medical visualization system by a respective camera, determining a magnification center for each of the channels, setting at least two magnification levels of a common mechanical magnification optical unit, identifying an image region which does not move or which moves the least across the magnification levels for each of the channels in image representations which are captured, and, proceeding from the respectively determined magnification centers, defining an image portion for each of the channels in the captured image representations with the respectively identified magnification center as the center, and restricting an output of the captured image representations at all magnification levels to the image portion defined for the respective channel.
An arrangement for OCT-based laser treatment of vitreous floaters. The arrangement for OCT-based laser vitreolysis includes an OCT system, a laser system having a deflection unit, optical elements that couple the OCT system and the laser system, a display unit and a central control and operating unit. The OCT system is configured to localize the floaters, the laser system is configured to destroy the floaters by application of laser pulses and the central control and operating unit is configured to determine apart from the coordinates of the localized floaters also their distance to structures of the eye, to derive exclusion criteria for the treatment, to align the deflection unit of the laser system to these coordinates and to focus and activate the laser system. The present invention relates to an arrangement for the gentle, low risk and painless laser treatment of vitreous floaters, which enables partially or fully automated therapy.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61F 9/009 - Dispositifs auxiliaires destinés à réaliser un contact avec le globe oculaire et un couplage de la lumière laser
6.
PHYSICAL AUGMENTATION OF PATIENT DATA FOR MEDICAL APPLICATIONS
A method for training a machine learning system with an extended set of patient data is described. This method includes measuring patient data and assigning ground truth data, determining the number of data pairs E/A, determining whether the number of data pairs lies below a previously defined training data threshold value, and if this is the case, carrying out the following steps: selecting a physical-optical model; using data pairs E/A in order to determine corresponding second output vectors A″ from input vectors E by means of the relation function R, determining a respective difference vector, modifying the input vectors by an ε-vector; determining third output vectors of the relation function; determining modified output vectors; and training a machine learning system by means of the modified data and the original data.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
7.
PHYSICAL IOL POSITION DETERMINATION ON THE BASIS OF DIFFERENT INTRAOCULAR LENS TYPES
A computer-implemented method for training a machine learning system to determine an expected offset for a physical postoperative lens position of an intraocular lens to be inserted. The method includes determining a plurality of theoretical positions in the eye of different intraocular lenses to be inserted, the determination including a respective use of a relation and a respective lens-specific constant for the plurality of the theoretical postoperative positions. The method includes: measuring a plurality of postoperative positions of the intraocular lens, with the real postoperative positions being assigned to respective associated theoretical postoperative positions; determining positional differences between theoretical postoperative positions and real postoperative positions; measuring associated ophthalmological biometry data for each tuple; and training a machine learning system to form a trained machine learning model for a prediction of the expected offset for a physical postoperative lens position.
A computer implemented method for determining a refractive power value of an intraocular lens to be inserted is described. The method includes measuring ophthalmological patient data, receiving a target refraction value, determining a first refractive power value of an intraocular lens to be inserted, with the measured ophthalmological patient data and the target refraction value being used as input data, determining, by means of a trained machine learning system, a second refractive power value of the intraocular lens to be inserted, the measured ophthalmological patient data and the received target refraction value being used as input data for the trained machine learning system, and determining the final refractive power value of the intraocular lens to be inserted from the first refractive power value and the second refractive power value by means of an individual boosting factor value.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G06N 20/20 - Techniques d’ensemble en apprentissage automatique
9.
CONTAINER DEVICE HAVING AN OPHTHALMIC INJECTOR HOLDING AN INTRAOCULAR LENS
A container has an ophthalmic injector holding an intraocular lens and a first vessel at least partially filled with a fluid. The intraocular lens is surrounded by the fluid and the first vessel is provided with a lid which closes the first vessel in a fluid-tight manner and which is releasably connected to the first vessel. A second vessel is coupled to the first vessel. A fluid-tight closure is provided between the first vessel and the second vessel, wherein the lid is coupled to the closure by a coupler, and, when the lid is released from the first vessel, the closure is configured, via the coupler, to pass from a closed position to an open position, such that the fluid can flow from the first vessel into the second vessel.
B65D 81/26 - Adaptations pour empêcher la détérioration ou l'altération du contenu; Applications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux avec dispositifs pour évacuer ou absorber les fluides, p.ex. s'écoulant du contenu; Emploi de produits empêchant la corrosion ou de dessiccateurs
B65D 77/20 - Fermetures des réceptacles formées après remplissage en appliquant des couvercles ou chapeaux séparés
B65D 81/22 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu fournissant une ambiance spécifique pour le contenu, p.ex. température supérieure ou inférieure à la température ambiante en condition d'humidité ou immergés dans un liquide
B65D 85/38 - Réceptacles, éléments d'emballage ou paquets spécialement adaptés à des objets ou à des matériaux particuliers pour objets particulièrement sensibles aux dommages par chocs ou compression pour appareils optiques de mesure, de calcul ou de commande délicats
10.
METHOD FOR OPERATING A MICROSCOPY SYSTEM, MICROSCOPY SYSTEM, AND CALIBRATION METHOD FOR A MICROSCOPY SYSTEM
A method for operating a microscopy system includes irradiating a region segment of a first region by a light source with light at a first wavelength λ1 and a first luminous intensity L1, determining a substance-specific parameter within the region segment as a response to being irradiated by the light source, and repeating the steps for all region segments within the first region. In addition, the disclosure relates to a microscopy system, and a calibration method for a microscopy system.
An injector for inserting an intraocular lens into a capsular bag of an eye includes an injector body having an injector tip defining an opening. The injector body has a proximal end facing away from the opening and has a distal end. A first piston is directed toward the opening and is configured to contact and displace the intraocular lens. A second piston is operable from outside of the injector and the first piston and the second piston are each configured to be longitudinally displaceable along the injector axis. A handle is operated from outside of the injector and is configured to be coupled to the first piston so that when the pistons are in the decoupling state, the first piston is displaced toward the opening and relative to the second piston by moving the handle.
A treatment apparatus for a cataract treatment of an eye includes a modular intraocular lens including a first part, which includes a haptic configured to contact a capsular bag of the eye in a region of the equator of the capsular bag and thereby to span the capsular bag, and a second part, which includes an optic body, and has a convergence state, in which the second part contacts the first part, and a spaced-apart state, in which the second part is arranged spaced apart from the first part, a measurement system configured to determine, based on a first measurement, a position of the first part in the eye and in the spaced-apart state of the modular intraocular lens, and a controller configured to determine, based on the position of the first part, a refractive power of the optic body which is to be inserted into the eye.
A61B 3/103 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p.ex. réfractomètres, skiascopes
13.
USING MULTIPLE SUB-VOLUMES, THICKNESSES, AND CURVATURES FOR OCT/OCTA DATA REGISTRATION AND RETINAL LANDMARK DETECTION
A system/method/device for registering two OCT data sets defines multiple image pairs of corresponding 2D representations of one or more corresponding sub-volumes in the two OCT data sets. Matching landmarks in the multiple image pairs are identified, as a group, and a set of transformation parameters are defined based on matching landmarks from all of the image pairs. The two OCT data sets may then be registered based on the set of transformation parameters.
An ophthalmic lens includes a lens body with a predetermined refractive effect and a ring-shaped, diffractive structuring. The ring-shaped, diffractive structuring (4-4) has a waveform in the radial direction which differs from a sinusoidal waveform by an asymmetry and/or a flattening and/or a periodicity, wherein the asymmetry and/or flattening and/or periodicity is constant or changes strictly monotonically over the entire radial curve of the waveform. Further, a method for designing an ophthalmic lens is disclosed.
A planning device for generating control data, a treatment apparatus for refraction correction eye surgery and a method for generating control data for such a treatment apparatus which allows an improved subsequent refraction correction. The planning device includes a calculation processor for defining a cut surface of the cornea for post-treatment, wherein the calculation device is designed such that a change of thickness of the epithelium is taken into account in the calculation, which was caused essentially by a pretreatment.
An apparatus for refractive lens surgery on the human eye, including: a laser device for separating tissue of the eye lens and capsular bag in a focus of pulsed laser radiation, a focus positioning device for setting and adjusting a location of the focus, a measuring apparatus for gathering the relative position of the eye lens and capsular bag, and a control device which reads data from the measuring apparatus and controls the focus positioning device, and which is designed to define and specify a pattern for the focus to the focus positioning device, the pattern separating tissue layers in the eye lens for the purposes of generating an accommodation space for an intralenticular intraocular lens. The accommodation space includes a cutout for a dimensionally-stable lens body of the intraocular lens and a peripheral fastening region for fixing the dimensionally-stable lens body at a single, predetermined, axial position.
An OCT system is constructed on a micro optical bench or semiconductor optical bench. The present OCT system may use free space optics and avoid the use of fiber optics.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/113 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
18.
METHOD, COMPUTER PROGRAM AND DATA PROCESSING UNIT FOR PREPARING OBSERVATION OF FLUORESCENCE INTENSITY, METHOD FOR OBSERVING FLUORESCENCE INTENSITY, AND OPTICAL OBSERVATION SYSTEM
What is provided is a method for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3) that comprises object regions (3A-H) that differ from one another in terms of their depth and/or their orientation, wherein the observation is intended to be implemented using an optical observation system (100) using which fluorescence radiation is able to be observed, provided that this has a certain minimum intensity. The method comprises the following steps:
determining the parameter value of at least one parameter which influences the observation of the fluorescence intensity, and
simulating the fluorescence intensity expected for the respective object regions (3A-H) on the basis of the determined parameter value of the at least one parameter and a model of the influence of the at least one parameter on the fluorescence intensity.
What is provided is a method for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3) that comprises object regions (3A-H) that differ from one another in terms of their depth and/or their orientation, wherein the observation is intended to be implemented using an optical observation system (100) using which fluorescence radiation is able to be observed, provided that this has a certain minimum intensity. The method comprises the following steps:
determining the parameter value of at least one parameter which influences the observation of the fluorescence intensity, and
simulating the fluorescence intensity expected for the respective object regions (3A-H) on the basis of the determined parameter value of the at least one parameter and a model of the influence of the at least one parameter on the fluorescence intensity.
Within the scope of the simulation, a minimum concentration of the fluorescent dye is predefined and the fluorescence intensity expected with the minimum concentration is determined for each object region (3A-H) based on the simulation.
What is provided is a method for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3) that comprises object regions (3A-H) that differ from one another in terms of their depth and/or their orientation, wherein the observation is intended to be implemented using an optical observation system (100) using which fluorescence radiation is able to be observed, provided that this has a certain minimum intensity. The method comprises the following steps:
determining the parameter value of at least one parameter which influences the observation of the fluorescence intensity, and
simulating the fluorescence intensity expected for the respective object regions (3A-H) on the basis of the determined parameter value of the at least one parameter and a model of the influence of the at least one parameter on the fluorescence intensity.
Within the scope of the simulation, a minimum concentration of the fluorescent dye is predefined and the fluorescence intensity expected with the minimum concentration is determined for each object region (3A-H) based on the simulation.
Also provided are a computer program, a computer-implemented method, a data processing unit (6) and an optical observation system (100) for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3).
The invention relates to a treatment apparatus having a modular intraocular lens, which comprises a first part having a haptic and a marking, visible in optical coherence tomography, with known dimensions of said marking and a second part having an optics body and which has a convergence state, in which the second part is in contact with the first part, and a spaced-apart state, in which the second part is spaced apart from the first part, having an optical coherence tomography device, which is configured to record, by means of optical coherence tomography, an OCT cross-sectional image which shows the first part arranged in a capsular bag of an eye and which shows dimensions of the marking in the OCT cross-sectional image, and having an evaluation unit which is configured to create a corrected OCT cross-sectional image by transforming coordinates of the OCT cross-sectional image in such a way that dimensions of the marking in the corrected OCT cross-sectional image are closer to the known dimensions of the marking than the dimensions of the marking in the OCT cross-sectional image.
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A microscopy system includes a tracking camera for pose detection of a marker, a device configured to determine a working distance, a movable optical element, the pose of which can be changed to set a capture region of the tracking camera and/or at least two tracking illumination devices, at least one optical element for beam guidance of the radiation generated by the tracking illumination devices, and a controller configured to control the movable optical element and/or the tracking illumination devices, in which the pose of the movable optical element can be set based on the working distance and/or in which an operating mode and/or an illumination region of the tracking illumination devices can be set based on the working distance. In addition, a method for operating a microscopy system is provided.
The present disclosure relates to a microscope and to an imaging method for a microscope. The microscope according to the invention comprises an illumination beam path, which is configured to couple excitation radiation from a light source onto an object to be examined; an optical filter, which is configured to select parts of the excitation radiation; a sensor for detecting an optical property of the excitation radiation; a measurement beam path (90), which is configured to guide a part of the excitation radiation onto the sensor; an observation beam path, which is configured to image radiation emitted by the object; wherein the optical filter is arranged in the beam path between the light source and the sensor, and an image generating means, which is configured to generate an image from the radiation emitted by the object and guided in the observation beam path; wherein the image generating means is configured to use the properties of the filtered excitation radiation that are detected by means of the sensor for the image generation.
G02B 21/16 - Microscopes adaptés pour éclairage ultraviolet
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
22.
METHOD, COMPUTER PROGRAM, AND DATA PROCESSING UNIT FOR CREATING AT LEAST ONE CORRECTION VALUE FOR CORRECTING FLUORESCENCE INTENSITIES IN A FLUORESCENCE IMAGE, AND OPTICAL OBSERVATION SYSTEM
A method for creating at least one correction value for correcting fluorescence intensities in a fluorescence image obtained with an optical observation system includes determining the parameter value of at least one parameter of the optical observation system which influences the observation of the fluorescence intensity, and generating the at least one correction value for correcting the fluorescence intensities in the fluorescence image based on the determined parameter value and the influence of the at least one parameter which influences the observation of the fluorescence intensity on the fluorescence intensities. A parameter of the illumination system serves as the at least one parameter which influences the observation of the fluorescence intensity. Additionally, a computer program, a computer-implemented method, a data processing unit, and an optical observation system for creating at least one correction value for correcting fluorescence intensities in a fluorescence image are provided.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
G06T 5/50 - Amélioration ou restauration d'image en utilisant plusieurs images, p.ex. moyenne, soustraction
23.
MICROSCOPY SYSTEM AND METHOD FOR OPERATING THE MICROSCOPY SYSTEM
A microscopy system includes a microscope, a stand configured to mount the microscope and including a drive device configured to move the microscope, a detection device configured to detect a spatial position of a target fastened to a body part or to an instrument, wherein the position detection device includes the target with at least one marker element and an image capture device configured to optically capture the target. The microscopy system further includes at least one control device configured to operate the microscopy system according to the detected position of the target, wherein the position detection device is configured to determine the position of the target by evaluating a two-dimensional image of the image capture device. In addition, a method for operating the microscopy system is provided.
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A system and method for multimodal image acquisition and image visualization, including a surgical-microscopic system with an optical unit and an image sensor and designed for acquiring a time-resolved image signal of a selected field of view of a sample. The system includes an OCT system, which is designed to acquire a time-resolved OCT signal of the selected field of view, a display means designed for the time-resolved display of image data and a control unit. The control unit is configured to ascertain video image data corresponding to the acquired image signal and to present them on the display means, to ascertain a time-resolved OCT image, corresponding at least to a portion of the presented video image data, on the basis of the acquired OCT signal, and to present the OCT image on the display means at the position of the portion.
H04N 13/239 - Générateurs de signaux d’images utilisant des caméras à images stéréoscopiques utilisant deux capteurs d’images 2D dont la position relative est égale ou en correspondance à l’intervalle oculaire
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
The present invention relates to a system for acquiring and visualizing OCT signals, comprising an OCT system and a display means designed for the time-resolved display of image data. The system further comprises a control unit configured to drive the OCT system to acquire a time-resolved OCT signal of a selected field of view of the sample and to determine a time-resolved OCT image on the basis of the acquired time-resolved OCT signal and a specifiable virtual viewing direction and to display the time-resolved OCT image on the display means. The present invention also relates to a corresponding method for acquiring and visualizing OCT signals.
H04N 13/117 - Transformation de signaux d’images correspondant à des points de vue virtuels, p.ex. interpolation spatiale de l’image les positions des points de vue virtuels étant choisies par les spectateurs ou déterminées par suivi du spectateur
H04N 13/207 - Générateurs de signaux d’images utilisant des caméras à images stéréoscopiques utilisant un seul capteur d’images 2D
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
The assembly for laser treatment of ocular opacities consists of: a measurement system for obtaining depth information regarding ocular structures; a laser system; an eye-tracker unit; a display unit; and a control-and-operating unit. According to the invention, the control-and-operating unit is designed to determine, from the depth profiles, the depth of ocular structures relative to the depth of the laser focus, and, in particular for the retina and the capsular bag, to determine a blocked zone for the laser treatment. Furthermore, the control-and-operating unit is designed to generate, at least for the blocked zones of the retina and capsular bag and the laser focus, at least one tag in each case, the characteristic of which corresponds to the particular depth in the eye, in order to display these tags on the display unit and to overlay them with the live image. The invention relates to a partially automated therapy apparatus for laser treatment of ocular opacities in which two-dimensional views of the eye are combined with three-dimensional imaging from the measurement system.
Using the present solution, it is possible both to determine optical aberrations and/or the topography and to simultaneously or immediately successively record reference images of an eye. Within the scope of the method, the eye is illuminated with different illumination patterns by means of an illumination unit, and the light reflected by the eye is recorded by a plenoptic camera sensor and evaluated by a control and evaluation unit. According to the invention, the eye is illuminated with different illumination patterns which differ in respect of their intensity distribution and illumination direction, the light reflected by the eye is imaged onto the plenoptic camera sensor and the topography and/or optical aberrations and/or reference images of the illuminated eye are determined from the image data of the plenoptic camera sensor on the basis of the utilized illumination pattern. Even though the solution is especially provided for applications in ophthalmology, it can also be applied in other specialist fields and in industry.
A61B 3/107 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
H04N 23/957 - Caméras ou modules de caméras à champ lumineux ou plénoptiques
H04N 23/56 - Caméras ou modules de caméras comprenant des capteurs d'images électroniques; Leur commande munis de moyens d'éclairage
29.
OPERATING MICROSCOPE HAVING AN ILLUMINATION DEVICE
A surgical microscope includes an optical assembly to image an object plane with a microscope main objective system, through which a first stereoscopic partial beam path with a first optical axis and a second stereoscopic partial beam path with a second optical axis pass. An illumination device includes a light source assembly to provide illumination light in a luminous plane, with a radiant field stop, and an illumination optical unit which at least partially images a luminous object arranged in the luminous plane in the illumination beam path into a luminous image plane located in the microscope main objective system or for the vertical distance z of which from the microscope main objective system on the side facing the object region or the side facing away from the object region, in relation to a focal length f of the microscope main objective system, the following applies: z/f<10%.
The invention relates to an ophthalmological implant (100) with an optically imaging element (110), a digital product identifier (130) being arranged on the optically imaging element. The invention additionally relates to a corresponding method for producing the implant and to a machine reading system (200) for detecting and decoding the digital product identifier. The aim of the invention is to provide an ophthalmological implant and a method for producing same, said method allowing a unique and complete product identifier and a check thereof using simple means at any point in time. This is achieved by an ophthalmological implant with a digital product identifier (130) which is implemented by means of an encoded point grid (135) of identifier points (57), said point grid being machine-readable in the visible light range and having one irregular semi-random character.
An ophthalmic imaging system has a specialized graphical user interface GUI to convey information for manually adjusting control inputs to bring an eye into alignment with the system. The GUI uses color and size changes to indicate axial positioning information of the system relative to a patient's eye. Furthermore, no live feed of the patient's eye is needed. Rather, a graphic indicating the patient's eye is provided and its size is controlled to indicate axial information and to filter out momentary movements of the pupil.
A system, method, and/or device for determinizing a quality measure of OCT structural data and/or OCTA functional data uses a machine learning model trained to provide a single overall quality measure, or a quality map distribution for the OCT/OCTA data based on the generation of multiple features maps extracted from one or more slab views of the OCT/OCTA data. The extracted feature maps may be different texture-type maps, and the machine model is trained to determine the quality measure based on the texture maps.
The invention relates to a planning device for generating control data for a treatment apparatus, which by means of a laser device generates at least one cut surface in the cornea, and to a treatment apparatus having such a planning device. The invention further relates to a method for generating control data for a treatment apparatus, which by means of a laser device generates at least one cut surface in the cornea, and to a corresponding method for eye surgery. The planning device is thereby provided with calculating means for defining the corneal incision surfaces, wherein the calculation means determines the corneal incisions such that after inserting an implant into the cornea, existing refractive errors are counteracted.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
34.
METHOD FOR CENTERING A CONTACT GLASS AND REFRACTIVE SURGICAL LASER SYSTEM
A method for centring a contact glass relative to a patient's eye includes a) providing a fixation light through a contact glass to align the patient's eye glass fixing on the fixation light; b) detecting an image of a light pattern that is imaged on the eye's surface; c) presenting the image over the eye with the contact glass with overlaying of virtual markings, wherein a first marking identifies the central axis of the contact glass and a second marking identifies a reference marking, which is derived from the image of the light pattern as lying on the central axis of the contact glass; d) laterally positioning the contact glass such that a distance between the markings is minimized; and e) establishing the position of the eye at which the second marking is located when the markings adopt the minimized distance and registering the position of the vertex.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
35.
METHOD FOR A MACHINE LEARNING SYSTEM FOR SURGERY ASSISTANCE
A method for training and using a machine learning system for a differentiation between healthy and diseased tissue during a microsurgical intervention is described. In this case, the method comprises: receiving training data and associated annotation data for training a machine learning system, training the machine learning system, which after training is configured for a prediction of a probability value and a prediction of a trustworthiness value, from which a control signal for a surgery assistance system is derivable, which is usable during a later application during a microsurgical operation, and storing parameter values of the trained machine learning model.
The present invention relates to a device for positioning an implant in an eye. The device includes an image recording unit, an image display unit, a control and evaluation unit and an implantation tool. The image recording unit provides images of the target area in the eye. The control and evaluation unit to detects eye structures in the images of the target area, to propose or to select a target region for the implant and to generate navigation data for the introduction of the implantation tool into the target region. The proposed device can be used for positioning implants in any regions of the eye.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
37.
Console for an ophthalmic surgical system for operating a handpiece, and ophthalmic surgical system
A console is for an ophthalmic surgical system for operating a handpiece driven by a work fluid. The work fluid is supplied to a respective work chamber depending on the switching states of work valves. The valves are switched between a switched-on state and a switched-off state by a respective drive unit by respective electrical switching signals being applied to the drive units. Each valve switches from the switched-off switching state into the switched-on switching state during a switch-on time delay and switches from the switched-on state to the switched-off state during a switch-off time delay. The switching signals at least intermittently adopt the switch-on electric potential concurrently during a difference time period if the switch-on delay is longer than the switch-off delay, with a length of time of the difference period arising on the difference between the switch-on delay and the switch-off delay of the valves.
A method for operating a medical radiation therapy arrangement is disclosed, wherein a wound cavity in the patient from which a tumor has been surgically removed is measured three-dimensionally in a reference coordinate system via a surgical microscope of the medical radiation therapy arrangement and/or via a probe-based registration device of the medical radiation therapy arrangement, wherein an x-ray applicator of an intraoperative radiation therapy device of the medical radiation therapy arrangement is selected and/or arranged in the wound cavity on the basis of three-dimensional measurement data generated during the measurement, with the x-ray applicator being navigable in the reference coordinate system. Furthermore, the disclosure relates to a medical radiation therapy arrangement.
An injector for inserting an intraocular lens into the capsular bag of an eye has an injector body; a plunger for displacing the lens out of the injector in an insertion direction, with the lens having an optic body with an optical axis and a rear and a front haptic; a rear mechanism for displacing an optic body distant longitudinal end of the rear haptic onto the optic body via a displacement of the plunger; a front mechanism for displacing an optic body distant longitudinal end of the front haptic along a front trajectory having a front component parallel to the optical axis; and a handle operable from outside of the injector and which has a first catch coupled to the plunger to carry along the plunger in the insertion direction via a longitudinal displacement of the handle and has a second catch to carry along the front displacement mechanism.
The invention relates to a method for operating a medical microscope, in particular in the field, with an interchange and/or a misalignment of at least one component of the medical microscope being followed by an identification of the interchanged and/or misaligned at least one component, with required adjustment measures and/or calibration measures being determined in automated fashion using the identified at least one interchanged and/or misaligned component as a starting point, and with the determined required adjustment measures and/or calibration measures being carried out. Furthermore, the invention relates to a medical microscope arrangement.
A method and associated system for operating a robotic visualization system comprising an imaging optical unit and a robotic arm for positioning the imaging optical unit within a surround. The method includes ascertaining a target field of view to be visualized by means of the imaging optical unit. Ascertaining a target pose of the robotic visualization system for capturing an image of the target field of view with a first imaging configuration of the imaging optical unit. Ascertaining a collision probability along a movement path of the robotic visualization system from a current pose to the ascertained target pose using a 3-D model of the surround. Ascertaining an adapted target pose for capturing an image corresponding to the target field of view with a second imaging configuration of the imaging optical unit using the 3-D model of the surround, should the ascertained collision probability exceed a predetermined threshold value.
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
The invention relates to a floor stand for an optical detection device, having a foot part comprising multiple bearing points or a planar standing surface that span a base plane, having a first stand arm which is pivotably connected to the foot part by a first joint on the foot part, and which is connected to a second stand arm by a second joint remote from the foot part, wherein the length of the first stand arm is dimensioned such that the distance between the base plane and the second joint is smaller than the sum of the maximum value for the eye level when seated and the maximum value for the length of the lower leg including the foot when the first stand arm is aligned at 45 degrees in relation to the base plane.
A holding element for a drape for a surgical microscope is provided. The holding element has a holding ring and a recess located in the holding ring for an interface of the surgical microscope. The holding ring has an asymmetrical contour delimiting the recess such that in a condition in which the holding element is fastened to the surgical microscope there is only one possible fastening position of the holding element on the interface of the surgical microscope that corresponds to the contour of the holding ring, in which position an orientation of the holding element relative to the surgical microscope is defined.
A method and device for adjusting and controlling parameters of the illumination area of ophthalmological devices including for example, brightness, color/color temperature, area shape, polarization state. The arrangement according to the invention includes an actuating unit that adjusts the desired lighting parameters, an illumination unit that generates illumination radiation having the desired illumination parameters, a decoupling element that decouples a part of the illumination radiation, a sensor element that analyzes the decoupled part of the illumination radiation and an evaluation unit that evaluates the sensor data and that determines the actual illumination parameters of the illumination radiation. According to an example embodiment of the invention, the sensor element is a spatially resolving image sensor. Embodiments of the invention are provided in particular for adjusting and controlling parameters of the illumination area of ophthalmological devices, but can also be applied to other technical fields, such as microscopy, for example.
A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
45.
CONTROLLED INJECTION BETWEEN TWO TISSUE LAYERS OF THE HUMAN EYE
A control device for controlling and/or regulating an injection flow rate, when injecting a fluid at an injection site between two tissue layers of the human eye with an injection flow rate that increases with time, is described, which comprises a controlling or regulating unit configured to control the injection flow rate in such a way that the injection flow rate increases during the injection for at least 30% of the injection time or during the injection of at least 30% of the injection volume.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
46.
CREATION OF CURVED CUTS IN THE INDSIDE OF THE EYE CORNEA
A device for isolating a lenticle in the cornea of an eye. The device includes: a laser beam source to emit pulsed laser radiation having a pulse frequency of 1.2 MHz to 10 MHz, a pulse energy of 1 nJ to 200 nJ and a wavelength penetrating the cornea; a beam-forming unit having beam optics with an image field and that bundles pulsed laser radiation into a focus located inside the image field, and which has a maximum diameter of less than 3 μm; a beam-deflection unit shifting the focus in the cornea and inside the image field, the focus moving along a path when the image field is resting; and a control unit to control the source and the beam-forming unit to isolate the lenticle by specifying the path. The lenticle is delimited by a cut surface which is curved with regard to a front surface of the cornea.
The present application describes the addition of various feedback mechanisms including visual and audio feedback mechanisms to an ophthalmic diagnostic device to assist a subject to self-align to the device. The device may use the visual and non-visual feedback mechanisms independently or in combination with one another. The device may provide a means for a subject to provide feedback to the device to confirm that an alignment condition has been met. Alternatively, the device may have a means for sensing when acceptable alignment has been achieved. The device may capture diagnostic information during the alignment process or may capture after the alignment condition has been met.
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
The present disclosure relates to a method of medical calibration, including the method steps of: capturing an image representation of a medical marker and of a medical instrument connected therewith; determining a spatial pose of the medical marker on the basis of the image representation; determining a first position of a tracking point of the medical instrument on the basis of the determined spatial pose and on the basis of information relating to a spatial pose relationship between medical marker and tracking point, and determining a second position of the tracking point on the basis of the captured image representation; determining a deviation between the first position and the second position; adjusting the information relating to the spatial pose relationship between medical marker and tracking point on the basis of the determined deviation.
The present disclosure relates to a method of medical navigation including the method steps of: capturing a first image representation of a medical marker in a first perspective; capturing a second image representation of the medical marker in a second perspective; determining a three-dimensional representation of the medical marker on the basis of the first image representation and the second image representation; capturing a third image representation of the medical marker; and determining a spatial pose of the medical marker on the basis of a comparison of the third image representation and the three-dimensional representation of the medical marker. The present disclosure further relates to a medical navigation system, to a computer program and to the use of a three-dimensional representation of a medical marker for registering a medical instrument, a patient and/or a piece of medical equipment.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
51.
METHOD FOR OPERATING A STEREOSCOPIC MEDICAL MICROSCOPE, AND MEDICAL MICROSCOPE
The invention relates to a method for operating a stereoscopic medical microscope, wherein deteriorated and/or invalid calibration data are recognized, wherein for this purpose mutually corresponding image representations of at least one feature arranged in capture regions of cameras of a stereo camera system of the medical microscope are captured by means of the cameras, the captured image representations are evaluated by means of feature-based image processing, wherein the at least one feature is recognized in this case in the captured image representations and a misalignment and/or a decalibration of the cameras of the stereo camera system are/is recognized on the basis of the at least one feature recognized; and wherein at least one measure is carried out depending on an evaluation result. Furthermore, the invention relates to a medical microscope.
G06T 7/80 - Analyse des images capturées pour déterminer les paramètres de caméra intrinsèques ou extrinsèques, c. à d. étalonnage de caméra
G06V 10/24 - Alignement, centrage, détection de l’orientation ou correction de l’image
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p.ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersections; Analyse de connectivité, p.ex. de composantes connectées
G06V 10/74 - Appariement de motifs d’image ou de vidéo; Mesures de proximité dans les espaces de caractéristiques
52.
METHOD FOR ADJUSTING AND/OR CALIBRATING A MEDICAL MICROSCOPE AND MEDICAL MICROSCOPE
The invention relates to a method for adjusting and/or calibrating a medical microscope, the following being implemented for at least one observer beam path of the medical microscope: capturing respective image representations of an object at different magnification levels of a zoom optical unit, and determining a zoom center using the captured image representations as a starting point, and i) capturing respective further image representations at different axis positions of at least one linear or rotational movement axis of the medical microscope, a rotation of the capture device relative to the at least one linear or rotational movement axis being determined using the captured further image representations as a starting point, and/or ii) capturing respective further image representations of the object in different focal planes and/or at different working distances in the case of an off-centered imaging optical unit, a rotation of the capture device being determined using the captured further image representations as a starting point, and a reference marking being determined using the determined zoom center and the determined rotation as a starting point and being provided for adjustment and/or calibration purposes. Further, the invention relates to a medical microscope.
An intraocular lens has an optic body, a haptic element mounted on the optic body and having a haptic curvature and a plurality of recesses on the side of the haptic element facing the optic body, a first actuator configured to reversibly change the haptic curvature of the haptic element such that the haptic element is moved away from the optic body from a rest position, a brace arm mounted on the optic body and the longitudinal brace arm end which is configured to be provided a recess when the haptic element is in the rest position, and a second actuator configured to reversibly change, with a change in a property of the second actuator, a brace arm curvature of the brace arm such that the recess in which the longitudinal brace arm end is to be provided can be adjusted with the property of the second actuator.
A plunger for an injector to inject an intraocular lens into the capsular bag of an eye has a deformable cushion and a contact surface with a cutout in which an imaginary reference point is arranged. The plunger has two points groups, each having a design point arranged on an outer contour, an inner contour point arranged on an inner contour, and a reference point. For each of the point groups, the distance from the design point to a circle or a closed curve is equal to the distance from the inner contour point to the reference point, the design point, the inner contour point and the reference point lie on a straight line, and the inner contour point lines between the design point and the reference point. The distance from the inner contour point to the reference point is different for at least two of the point groups.
Tissue adhesive for use in a treatment method in which an ophthalmological implant is implanted in a human or animal patient, and ophthalmological implantation system
The disclosure relates to a tissue adhesive for use in a treatment method in which an ophthalmological implant is implanted in a human or animal patient and the ophthalmological implant is connected, at least partially in an integrally bonded manner, to eye tissue of the patient via the tissue adhesive. The disclosure also relates to an ophthalmological implantation system including an ophthalmological implant for implantation in a human or animal eye and to a tissue adhesive via which the ophthalmological implant is connectable, at least partially in an integrally bonded manner, to eye tissue of the patient.
A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à quatre chaînons, p.ex. taxol
A61K 31/78 - Polymères contenant de l'oxygène d'acide acrylique ou de ses dérivés
A61K 38/18 - Facteurs de croissance; Régulateurs de croissance
A61L 24/04 - Adhésifs ou ciments chirurgicaux; Adhésifs pour dispositifs de colostomie contenant des matériaux macromoléculaires
56.
MEDICAL OPTICAL SYSTEM, DATA PROCESSING SYSTEM, COMPUTER PROGRAM, AND NON-VOLATILE COMPUTER-READABLE STORAGE MEDIUM
The invention relates to a medical optical system. The medical optical system comprises: —a microendoscope (3) for capturing histological images, each of which displays a microscopic tissue section (16) of a macroscopic tissue region (15) with a tumor (23); and—a classification device (31) for classifying the macroscopic tissue sections (16) displayed in the histological images as at least one respective tissue section that represents the tumor (23) or a tissue section that represents healthy tissue and for outputting a classification result for each classified microscopic tissue section (16). The medical optical system additionally comprises a combination device (37) which generates a macroscopic classification image (43) by combining the classification results, said classification image representing the location of the tumor (23) in the macroscopic tissue region (15).
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
A61B 1/04 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision
A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p.ex. DICOM, HL7 ou PACS
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p.ex. pour des analyses d’échantillon de patient
57.
EQUIPMENT AND METHODS FOR REFRACTIVE SURGERY, PARTICULARLY FOR KERATOPLASTY
Equipment and methods for refractive surgery, including for keratoplasty. The invention describes equipment and methods for the production and implantation of a lamella of a tissue or material for the purpose of correcting a corneal geometry at maximum precision that is thus improved in relation to the prior art. The invention facilitates restoration of normal corneal geometry together with optical functionality of the cornea which is improved in relation to the prior art. A planning device, a treatment system and a planning method are designed to couple a device coordinate systems of the laser devices involved and characterization devices by application of registration and to uniquely register the supplied measurement data for generating the lamella to be implanted to the device coordinate systems by a specific, defined edge geometry of a blank from which the lamella is produced, and by the lamella, and by additional system and method aids.
The present invention relates to a stent implant for treating glaucoma by means of intraocular fluid drainage from the anterior chamber, preferably in the suprachoroidal space. The stent implant according to the invention is designed to bring about a change in shape after being inserted into the eye, during which change the width and/or thickness or the flow cross-section is increased by more than 20%, preferably more than 200%, and particularly preferably by more than 400%, at at least one point of the stent implant. In the case of intraocular fluid drainage from the anterior chamber into the suprachoroidal space, a cyclodialysis cleft which may open can therefore be at least largely or completely closed. The proposed stent implant is provided in particular for intraocular fluid drainage into the suprachoroidal space. With appropriate adjustments, the stent implant can also be applied in trabecular, uveoscleral, uveolymphatic and subconjunctival applications for intraocular fluid drainage from the anterior chamber. Said implant can even be used for direct intraocular fluid discharge from the anterior chamber onto the surface of the eye.
A surgical microscope for visualizing a tissue region contains an illumination device with a light source and an illumination beam path for illuminating an object region with an object plane and an observation device having an observation beam path for imaging the object region with the object plane into an observation plane. A first polarizer can be coupled into the illumination beam path and is suitable for polarizing the illumination light in a first orientation. A polarizer, which can be coupled into the observation beam path, has a second orientation at an angle between 80° and 100° relative to the first orientation. In a first mode, the light source emits illumination light in a first wavelength range between 450 nm and 550 nm, the first polarizer is coupled into the illumination beam path, and the second polarizer is coupled into the observation beam path.
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
60.
UV-LASER-BASED SYSTEM FOR REFRACTIVE ERROR CORRECTION, AND CONTACT INTERFACE
An ultraviolet laser-based (UVL) laser vision correction (LVC) system, a contact interface and a contact interface system for such a UVL-LVC system. The invention facilitates a coupling and affixation between the patient's eye and the UVL-LVC system by application of a contact interface for the purposes of preventing eye movements when using UVL-LVC systems. The invention includes a UVL-LVC system with a base unit and an application arm which has a contact interface adapter on an application part of the application arm, to which a contact interface is affixable, the contact interface being usable to be to affix a patient's eye to the UVL-LVC system. The contact interface may have a conical wall and a suction ring but not a lens element, and optionally has an access opening or a corresponding contact interface system made of a contact interface adapter and a contact interface.
An ophthalmo-surgical injector includes an injector body, a tip with which an intraocular lens can be pressed out of the injector, a first plunger mounted longitudinally displaceably on the injector body and having a first projection, a shaft rotatably mounted in the injector body and having a first guide and a second guide which are each wound about the shaft, and a second plunger mounted longitudinally displaceably on the injector body and having a second projection. The first projection engages in the first guide, such that the first plunger is configured to effect, with a longitudinal displacement of the first plunger, a rotation of the shaft about a longitudinal axis of the injector body, and the second projection engages in the second guide, as a result of which the shaft is configured to effect, with the rotation effected by the first plunger, a longitudinal displacement of the second plunger.
A method for operating a microscopy system and to a microscopy system are provided. A pivot point is defined, wherein the microscopy system is operated such that a microscope of the microscopy system moves at a constant distance around the pivot point, wherein a reference surface is determined, wherein an intersection of an optical axis of the microscope and the reference surface is determined as the pivot point, wherein the pose of the reference surface is defined in a focal position-independent reference coordinate system and the pivot point is determined as the intersection of the optical axis with the thus defined reference surface in the reference coordinate system.
A method for aligning a system for laser-based ametropia correction relative to a patient's eye to be treated is disclosed. Predefined pre-operative measurement data which characterize at least predetermined structures of the patient's eye is provided. The predetermined structures include a part of the patient's eye to be treated. In addition, the method includes measuring at least one part of the predetermined structures of the patient's eye using an OCT system immediately before and/or during treatment for ametropia correction of the patient's eye and providing OCT measurement data, and comparing the OCT measurement data and the predefined pre-operative measurement data and preparing comparative data. The method also includes ascertaining a position and/or orientation of the part of the patient's eye to be treated relative to the system and aligning the system relative to the patient's eye using the ascertained position and/or orientation of the part of the patient's eye.
A focusing optical system for a UVL-LVC system with a UV laser source and a scanning system that focuses a laser in a focal field and a lens assembly with a convergent focal field. The invention further includes a planning unit that generates planning data for a UVL-LNC system with a UV laser source, a scanning system, a focusing optical system, and a control unit for controlling the UVL-LVC system while taking into consideration planning data, wherein the planning unit takes into consideration geometry losses, Fresnel losses, and/or a spatial extension of laser radiation on a working surface while calculating the planning data, and the planning unit has an interface that provides the planning data. Finally, the invention includes a UVL-LVC system with a UV laser source, a scanning system, a focusing optical system according to the invention, a planning unit according to the invention, and a control unit.
An illumination apparatus for illuminating an examination object, in particular for illuminating a fundus section of a patient's eye, includes at least one light source which emits light onto a micromirror actuator, which is controllable by a control device for the purpose of preshaping the wavefront reflected by the micromirror actuator, and at least one light guide configured to guide the reflected light of the light source that has been preshaped by the micromirror actuator to an examination object. The light guide includes a first end for coupling light into the light guide and a second end for coupling light out of the light guide. In addition, an illumination method, and also an illumination system and a method for operating an illumination system are provided.
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
G02B 26/08 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander la direction de la lumière
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
66.
Injector assembly for inserting an intraocular lens and injector
The invention relates to an injector assembly comprising a folding chamber which is designed to receive an intraocular lens having a lens body and two haptics, and comprising a holder, a folding wedge which is attached to the holder and is designed to be introduced into the folding chamber in an insertion direction via a folding chamber opening and to thereby fold the intraocular lens, and two sliders which are each designed to shift one of the two haptics onto the lens body via a shifting of the respective slider out of an initial position and into an end position, wherein at least one of the two sliders has a stop which is designed to abut a component attached to the holder in the initial position of the at least one slider, whereby a movement of the component is blocked and the folding wedge is thereby not permitted to fold the intraocular lens, and said stop is designed to permit the movement of the component in the end position of the at least one slider and the folding wedge is thereby permitted to fold the intraocular lens.
The invention relates to an injector assembly having: a folding chamber which is designed to receive an intraocular lens which has an optical body and two haptic elements; a holder; a folding wedge which is attached to the holder and is designed to be introduced into the folding chamber via a folding chamber opening, thereby folding the intraocular lens; and a first slider and a second slider which are each designed to push one of the two haptic elements onto the optical body by means of a displacement of the respective slider from a starting position to an end position, the holder being designed to drive the first slider and/or the second slider from the starting position to the end position by means of a movement of the holder towards the folding chamber.
A diffractive eye lens having a front side, a rear side and an optical main axis, wherein the front side and/or the rear side has a spherical, an aspherical, a spherical-toric or an aspherical-toric basic shape, and the front side and/or the rear side has a diffractive optical structure. The diffractive eye lens allows for color correction and simultaneously improves visual properties by reducing a halo. The diffractive optical structure in a first lens region is designed such that, at a design wavelength, there is a significant diffraction efficiency for a phase deviation between the first main sub-zones of more than one wavelength and, for the first lens region, On average over all diffraction zones, a proportion of the main sub-zones on the diffraction zones is for example at least 94%, at least 95% and at best nearly 100%.
A UV-laser-based system (UVL-LVC system) for correcting the impaired vision of a patient's eye has a UV-laser source, which emits laser radiation to treat the patient's eye, and imaging optics for focusing the laser radiation onto the cornea of the patient's eye. The imaging optics allow a detection of a reflection of radiation, which is emitted onto the cornea of the patient's eye with the imaging optics and is at least partly reflected by the cornea of the patient's eye back into the imaging optics at an acceptance angle χMax of at least 2.5°. Additionally a method for centering a UVL-LVC system is disclosed.
Retinal layer segmentation in optical coherence tomography (OCT) data is improved by using OCT angiography (OCTA) data to enhance a target retinal layer within the OCT data that may lack sufficient definition for segmentation. The OCT data is enhanced based on a mixture of the OCT data and OCTA data, such that contrast in the OCT data is enhanced in areas where OCT and OCTA data are dissimilar, and is reduced in areas where the OCT and OCTA data are similar. The target retinal layer in the OCT data is segmented based on the enhanced data. Two en face images of the OCTA data that include the target retinal layer are used to check for errors in the segmentation of the target retinal layer in the OCT data. Identified errors are replaced with an approximation based on the locations of top and bottom retinal layers of one of the en face images.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
71.
TARGET APPARATUS FOR USE IN A SURGICAL NAVIGATION SYSTEM, SURGICAL NAVIGATION SYSTEM, AND METHOD FOR PRODUCING SUCH A TARGET APPARATUS
The invention relates to a target apparatus for use in a surgical navigation system, comprising at least one marker, for pose determination both by way of a device for marker reference point-based pose determination using at least two image capturing devices for imaging the marker and by way of a device for marker shape-based pose determination using at least one further image capturing device for imaging the marker , the marker having a detection surface, the detection surface having at least one first region and at least one further region, wherein the first region is designed to be more reflective than the further region, at least one portion of the first region and at least one portion of the at least one further region forming a pattern for identifying the marker, and to a surgical navigation system and a method for producing the target apparatus.
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
An eye lens having a front lens element and a rear lens element, which each have a positive optical power and an optical region, and an intermediate element, which is connected to the lens elements outside the optical regions so that the lens elements and the intermediate element form a cavity. The eye lens allows the width of an access incision necessary for implantation to be reduced. The eye lens includes the lens elements and the intermediate element that are shaped such that, in the implanted state, a distance between the front lens element and the rear lens element is fixed and the cavity has an opening which allows liquid to flow into the cavity. Embodiments of the invention include a method for producing such an eye lens and a method for implantation.
A system and method for ophthalmic motion tracking. An anchor point and multiple auxiliary points are selected from a reference image. Individual live images in a series of images are then searched for matches of the anchor point and auxiliary point. First, the anchor point is found, and then searches for individual auxiliary points is limited to a search window defined by the known distance and/or orientation of the sought auxiliary point relative to the anchor point.
A61B 3/113 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
G06T 7/246 - Analyse du mouvement utilisant des procédés basés sur les caractéristiques, p.ex. le suivi des coins ou des segments
74.
OCT EN FACE PATHOLOGY SEGMENTATION USING CHANNEL-CODED SLABS
A system and method for use with optical coherence tomography (OCT) data to identify a target pathology extracts multiple pathology-characteristic images from the OCT data. The extracted pathology-characteristic images may include a mixture of OCT structural images (including retinal layer thickness information) and OCT angiography images. Optionally, other pathology-characteristic images and data maps (mapped to corresponding positions in the OCT data), such as fundus images and visual field test maps may be accessed as additional pathology-characteristic images. Each pathology-characteristic image defines a different image channel (e.g., “color channel”) per pixel in a composite, channel-coded image, which is then used to train a neural network to search for the target pathology in OCT data. The trained neural network may then receive new composite, channel-coded image and identify/segment the target pathology within the new channel-coded image.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
75.
INTRAOCULAR LENSES WITH INTEGRATED LOCKING UNIT FOR A HAPTIC CLAMP
Provided is an intraocular lens having at least one optical part and having a haptic coupled to the optical part, and having an optical principal axis that passes through a front side and a back side of the optical part, the haptic comprising at least one haptic loop, wherein a coupling element of the intraocular lens is integrated on the haptic loop and a mating coupling element of the intraocular lens is integrated on the optical part or on a connector coupled to the optical part, the coupling element being formed for direct coupling to the mating coupling element and, in the coupled state of coupling element and mating coupling element, an outer edge segment of the haptic loop being arranged at a radially shorter distance from the optical part than in the case of the uncoupled state of coupling element and mating coupling element.
The invention relates to a method for producing an intraocular lens, including the steps of providing a container which is transparent to electromagnetic radiation and in which a liquid that is curable by the electromagnetic radiation is arranged; irradiating the liquid with a set of images formed by the electromagnetic radiation, which each depict an intraocular lens, with each of the images of the set being radiated into the liquid at a different angle of incidence with respect to a reference plane that extends through the liquid, as a result of which the liquid is cured and the cured liquid forms the intraocular lens, an actuator, a solar module and/or a sensor being arranged in the liquid and the intraocular lens being formed around the actuator, the solar module and/or the sensor.
B29C 35/08 - Chauffage ou durcissement, p.ex. réticulation ou vulcanisation utilisant l'énergie ondulatoire ou un rayonnement corpusculaire
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
The invention relates to an intraocular lens comprising an optics body and a haptic which has a first component with a latching protrusion and a second component with a latching recess, the latching protrusion and the latching recess being arranged at a distance from one another when the haptic is arranged in a relaxed state and being configured to engage with one another when, proceeding from the relaxed state, the haptic is moved in the direction of the optics body into a completely compressed state of the haptic via a partially compressed state of the haptic, the haptic being formed by a single piece and having a haptic cutout which is delimited by the first component and the second component.
A system and/or method uses a trained U-Net neural network to remove flow artifacts from optical coherence tomography (OCT) angiography (OCTA) data. The trained U-Net receives as input both OCT structural volume data and OCTA volume data, but expands the OCTA volume data to include depth information. The U-Net applies dynamic pooling along the depth direction and weighs more heavily the portion of the data that follows (e.g., along the contours of) select retinal layers. In this manner the U-Net applies contextually different computations at different axial locations based at least in part on the depth index information and/or (e.g., proximity to) the select retinal layers. The U-net outputs OCT volume data of reduced flow artifacts as compared with the input OCTA data.
The invention relates to a head-mounted visualization system having a wearing system, at least one light-transmissive optical system, an image generation device designed to generate image information based on the image data supplied to the image generation device, wherein the optical system is designed to supply image information generated by the image generation device to a person wearing the visualization system, and a polarization unit designed to polarize light penetrating the optical system differently in two spatial regions. The invention further relates to a surgical visualization system having such a head-mounted visualization system and to a visualization method for a surgical environment.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
G02B 30/25 - Systèmes ou appareils optiques pour produire des effets tridimensionnels [3D], p.ex. des effets stéréoscopiques en fournissant des première et seconde images de parallaxe à chacun des yeux gauche et droit d’un observateur du type stéréoscopique utilisant des techniques de polarisation
83.
TUBE FOR A MEDICAL TREATMENT SYSTEM, AND MEDICAL TREATMENT SYSTEM
A tube for a medical treatment system has a first channel for feeding an irrigation fluid from a console of the system to a medical treatment instrument of the system and a second channel for discharging an aspiration fluid from the instrument to the console. The first and the second channels are arranged in parallel. The first channel has a first wall and the second channel has a second wall. A second material of the second wall has a greater hardness than a first material of the first wall. The tube is formed from two individual tube elements for the channels. The tube elements are welded or adhesively bonded in a connection region. The difference between the hardness of the first material and the hardness of the second material is at least 10 ShA and at most 15 ShA.
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61M 1/00 - Dispositifs de succion ou de pompage à usage médical; Dispositifs pour retirer, traiter ou transporter les liquides du corps; Systèmes de drainage
84.
SURGICAL MICROSCOPE HAVING A CONNECTION REGION FOR ATTACHING A PROTECTIVE GLASS MODULE
A surgical microscope includes an image capture unit having an image sensor, a detection beam path, an image evaluation unit, a connection region for attaching a protective glass module with an objective protective glass. The image sensor has a detection region which has a used detection region for capturing the object region, and a partial detection region, which is not assigned to the used detection region. The image capture unit is configured such that, when the protective glass module with the objective protective glass is arranged at the connection region, a detail of the protective glass module with the objective protective glass is capturable by the partial detection region of the image sensor. The image evaluation unit is configured to generate a signal when an objective protective glass is detectable by the evaluation of the image data of the partial detection region of the image sensor.
G06V 10/22 - Prétraitement de l’image par la sélection d’une région spécifique contenant ou référençant une forme; Localisation ou traitement de régions spécifiques visant à guider la détection ou la reconnaissance
H04N 9/797 - Traitement des signaux de télévision en couleurs en combinaison avec l'enregistrement pour enregistrer le signal dans plusieurs canaux, la largeur de bande de chaque canal étant inférieure à la largeur de bande du signal
85.
METHOD FOR OPERATING A FLUID PUMP, AND OPHTHALMIC SURGICAL SYSTEM WITH SAME
A cartridge for a panel of an ophthalmic surgical system for treating an eye is configured for insertion in a cartridge accommodation region of the panel and has at least one fluid pump for conveying a treatment fluid, the fluid pump has a pump chamber and a drive chamber separated from the pump chamber with a partition element that is at least regionally deflectable, wherein a drive fluid is feedable to the drive chamber and the treatment fluid is feedable to the pump chamber. The partition element has at least one plate element made of an at least electrically conductive or at least ferromagnetic material, said plate element also being deflected in the case of a deflection of at least one region of the partition element. Further, a panel and an ophthalmic surgical system are provided.
A console for a medical treatment system includes a console housing and a control unit for controlling a medical treatment instrument. A foot-operated control unit wirelessly coupled to the control unit, and the console housing has at least one side wall, which has a bearing surface for arranging the foot-operated control unit in a not-in-use position. The bearing surface is inclined with respect to a horizontal plane, at least in the region where the foot-operated control unit is arranged, in order when arranging the foot-operated control unit on the bearing surface to bring about bearing of the foot-operated control unit against the bearing surface by the weight of the foot-operated control unit. The side wall has in the region of the bearing surface a console-side connecting unit for releasably connecting the foot-operated control unit to the console. Further, a corresponding foot-operated control unit and a medical treatment system are provided.
A head-mounted visualization unit is provided with an at least partially light-transmissive optical system. The optical system has a first optical channel assigned to a first eye of a user and a second optical channel assigned to a second eye of the user. The first optical channel is substantially transmissive to optical radiation of a first polarization and substantially opaque to optical radiation of a second polarization, with the first polarization substantially orthogonal to the second polarization. The second optical channel is substantially transmissive to optical radiation of the second polarization and substantially opaque to optical radiation of the first polarization. A polarizer and a light attenuator are arranged in the first optical channel. The light attenuator is arranged downstream of the polarizer in a direction toward the first eye of the user.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
G02B 5/30 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES Éléments optiques autres que les lentilles Éléments polarisants
G02B 30/25 - Systèmes ou appareils optiques pour produire des effets tridimensionnels [3D], p.ex. des effets stéréoscopiques en fournissant des première et seconde images de parallaxe à chacun des yeux gauche et droit d’un observateur du type stéréoscopique utilisant des techniques de polarisation
G02B 27/28 - Systèmes ou appareils optiques non prévus dans aucun des groupes , pour polariser
An ophthalmic surgical cartridge has a fluid pump with a pump chamber and a drive chamber which are separated by a fluid-tight and ion-tight partition element. A body fluid is suppliable to the pump chamber and a drive fluid is suppliable to the drive chamber. A deformation or change in position of a portion of the partition element is achievable with the drive fluid which increases the second volume in size and decreases the first volume in size to drain the body fluid from the pump chamber. The drive chamber has a front side wall with an edge zone in which only a single passage opening is provided, through which the drive fluid is suppliable into the drive chamber to fill the drive chamber with the drive fluid, and through which said drive fluid can be drained from the drive chamber to remove the drive fluid from the drive chamber.
A61M 1/00 - Dispositifs de succion ou de pompage à usage médical; Dispositifs pour retirer, traiter ou transporter les liquides du corps; Systèmes de drainage
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
89.
CASSETTE FOR A CONSOLE OF AN OPHTHALMOSURGICAL SYSTEM, AND OPHTHALMOSURGICAL SYSTEM
A cassette for a console of an ophthalmosurgical system for treating an eye is configured for insertion into a cassette receiving region of the console and has a fluid pump configured to deliver a treatment fluid, a tube for attachment to a handpiece, and a connection unit secured against detachment, of a cassette-side end of the tube to a cassette housing of the cassette. The connection unit includes an attachment stub arranged on the cassette housing and has a through opening for the treatment fluid, and a plug-in connector arranged on the cassette-side end of the tube and likewise has a through opening for the treatment fluid, with the plug-in connector, when it is connected to the attachment stub, being held in a fluid-tight manner with respect to the attachment stub and so as to be able to rotate about a longitudinal axis of the through opening.
The invention relates to a computer-implemented method for a machine learning-supported processing pipeline for determining parameter values for an intraocular lens to be inserted. The method comprises providing a scan result of an eye. The scan result is an image of an anatomical structure of the eye. The method further comprises determining biometric data of the eye from the scan results of an eye and using a first, trained machine learning system for determining a final position of an intraocular lens to be inserted, ophthalmological data being used as input data for the first machine learning system. The method further comprises determining a first optical power of the intraocular lens to be inserted, which is based on a physical model in which the determined final position of the intraocular lens and the determined biometric data are used as input variables for the physical model.
The invention relates to a computer-implemented method and a corresponding system for a machine-learning-supported determining of refractive power for a measure for correcting the eyesight of a patient. The method involves providing a scan result of an eye, wherein the scan result represents an image of an anatomical structure of the eye. The method also involves supplying the scan result as input data to a first machine-learning system in the form of a convolutional neural network, and using output values of the first machine-learning system as input data for a second machine-learning system in the form of a multi-layer perceptron, and a target refraction value for the second machine-learning system is used as an additional input value for the second machine-learning system. Finally, the method involves determining parameters for the measure for correcting the eyesight of a patient via an immediate and direct cooperation of the first machine-learning system and the second machine-learning system.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
92.
Computer-implemented method, computer program and surgical system for determining the volumetric flow rate of blood through a portion of a blood vessel in a surgical field
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G06V 10/50 - Extraction de caractéristiques d’images ou de vidéos en utilisant l’addition des valeurs d’intensité d’image; Analyse de projection
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p.ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersections; Analyse de connectivité, p.ex. de composantes connectées
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
A system, method, or device for imaging the anterior segment of an eye includes a contactless adapter/lens that may be attached to an existing ophthalmic imaging system to redirect the imaging system's light beam to traverse the pupil of the eye at a steep angle. In particular, the steep angle is determined to permit the ophthalmic imaging system to image zonules under the iris, and which would typically be blocked by the iris and not accessible for imaging.
A61B 3/117 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner la chambre antérieure ou l'angle de la chambre antérieure, p.ex. gonioscopes
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
The invention relates to a computer-implemented method for identifying a region (21) of a tumour (23) in a tissue-field image (27), which image shows a tissue region (25) having a tumour (23) and has been obtained by means of light reflected or emitted by the tissue region (25). In the method, the region (21) of the tumour (23) in the tissue-field image (27) is identified on the basis of a characteristic value for the intensity of at least one component of the light reflected or emitted by the tissue region (25). The characteristic value is determined using the intensity of the at least one component in an image detail of the tissue-field image (27), which image detail corresponds to a tissue portion (36, 36′) of the tissue region (25) at which at least one piece of histological information was obtained.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
The invention relates to a computer-assisted method for position determination for an intraocular lens supported by machine learning. The method comprises providing a scan result for an eye. The scan result here represents an image of an anatomical structure of the eye. The method further comprises use of a trained machine learning system for the direct determination of a final location of an intraocular lens to be fitted, wherein digital data of the scan of the eye is used as the input data for the machine learning system.
ASSEMBLY COMPRISING AN OCT DEVICE FOR ASCERTAINING A 3D RECONSTRUCTION OF AN OBJECT REGION VOLUME, COMPUTER PROGRAM, AND COMPUTER-IMPLEMENTED METHOD FOR SAME
The invention relates to an assembly (10) comprising an OCT device (20) for scanning an object region volume (22) arranged in an object region (18) using an OCT scanning beam (21), an object (24) with a section, which can be arranged in the object region (18) and which can be located in the object region volume (22) by means of the OCT device (20), in the object region volume (22), and a calculating unit (60) which is connected to the OCT device (20) and contains a computer program for ascertaining a 3D reconstruction of the object region volume (22) and for ascertaining the position of the section of the object (24) in the object region volume (22) by processing OCT scanning information obtained by scanning the object region volume (22) using the OCT device (20). According to the invention, the computer program has a calculation routine for ascertaining a target area (90) in the 3D reconstruction of the object region volume (22), said calculation routine determining a reference variable for the object (24) relative to the target area (90). The object (24) is designed as a surgical instrument which has a capillary with an opening for discharging a medium. The calculation routine of the computer program is used to ascertain an actual value of the volume of the medium discharged through the opening of the capillary in the target area by comparing data of the target area in the 3D reconstruction of the object region volume (22) and/or by comparing scanning information of the target area obtained by scanning the object region volume (22) using the OCT device (20) prior to and while discharging the medium. The invention also relates to a computer program and to a method for determining the volume of a medium discharged in an object region (18) through an opening by means of a surgical instrument with a capillary.
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
G06T 7/30 - Détermination des paramètres de transformation pour l'alignement des images, c. à d. recalage des images
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
99.
ASSEMBLY COMPRISING AN OCT DEVICE FOR ASCERTAINING A 3D RECONSTRUCTION OF AN OBJECT REGION VOLUME, COMPUTER PROGRAM, AND COMPUTER-IMPLEMENTED METHOD FOR SAME
The invention relates to an arrangement 10 with an OCT device 20 for scanning an object region volume 22 arranged in an object region 18 with an OCT scanning beam 21, comprising an item 24 which has a section 84 that is arrangeable in the object region 18 and is localizable in the object region volume 22 by means of the OCT device 20, and having a computing unit 60 connected to the OCT device 20 and having a computer program for determining a 3-D reconstruction of the object region volume 22 and determining the location of the portion of the object 24 in the object region volume 22 by processing OCT scan information obtained with the OCT device 20 by scanning the object region volume 22. According to the invention, the computer program has a calculation routine for determining a target area in the 3-D reconstruction of the object region volume 22, which routine determines a reference variable for the object 24 for the target area. The computer program contains a path planning routine that uses a criterion to calculate an optimal path for object 24 to the target spatial position, the criterion being a shadow measure that quantifies the occurrence of shadows caused by object 24 in the calculated 3-D reconstruction. The invention also relates to a computer program and a method for determining a 3-D reconstruction of an object region volume 22 in an object region 18.
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
G06T 7/30 - Détermination des paramètres de transformation pour l'alignement des images, c. à d. recalage des images
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
100.
PHYSICALLY MOTIVATED MACHINE LEARNING SYSTEM FOR AN OPTIMIZED INTRAOCULAR LENS CALCULATION
A computer-implemented method for determining the refractive power of an intraocular lens to be inserted is presented. The method includes generating first training data for a machine learning system on the basis of a first physical model for a refractive power for an intraocular lens and training the machine learning system by means of the first training data generated, for the purposes of forming a first learning model for determining the refractive power. Furthermore, the method includes training the machine learning system, which was trained using the first training data, using clinical ophthalmological training data for forming a second learning model for determining the refractive power and providing ophthalmological data of a patient and an expected position of the intraocular lens to be inserted. Moreover, the method includes predicting the refractive power of the intraocular lens to be inserted by means of the trained machine learning system and the second learning model. In the process, the ophthalmological data provided and the position of the intraocular lens are used as input values for the machine learning system with the second learning model.
brevets
