A method and a system for calibrating cameras of a multichannel medical visualization system, including capturing a capturing region respectively imaged via channels of the multichannel medical visualization system by a respective camera, determining a magnification center for each of the channels, setting at least two magnification levels of a common mechanical magnification optical unit, identifying an image region which does not move or which moves the least across the magnification levels for each of the channels in image representations which are captured, and, proceeding from the respectively determined magnification centers, defining an image portion for each of the channels in the captured image representations with the respectively identified magnification center as the center, and restricting an output of the captured image representations at all magnification levels to the image portion defined for the respective channel.
A computer-implemented method for determining the refractive power of an intraocular lens includes providing a physical model for determining refractive power and training a machine learning system with clinical ophthalmological training data and associated desired results to form a learning model for determining the refractive power. A loss function for training includes: a first component taking into account clinical ophthalmological training data and associated and desired results and a second component taking into account limitations of the physical model wherein a loss function component value is greater the further a predicted value of the refractive power during the training is from results of the physical model with the same clinical ophthalmological training data as input values. Moreover, the method includes providing ophthalmological data of a patient and predicting the refractive power of the intraocular lens to be used by means of the trained machine learning system.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
Systems and methods for improved interferometric imaging are presented. One embodiment is a partial field frequency-domain interferometric imaging system in which a light beam is scanned in two directions across a sample and the light scattered from the object is collected using a spatially resolved detector. The light beam could illuminate a spot, a line or a two-dimensional area on the sample. Additional embodiments with applicability to partial field as well as other types of interferometric systems are also presented.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
G01B 9/02004 - Interféromètres caractérisés par la commande ou la génération des propriétés intrinsèques du rayonnement utilisant plusieurs fréquences utilisant le balayage des fréquences
G01B 9/02015 - Interféromètres caractérisés par la configuration du parcours du faisceau
The system, method and device includes an optical coherence tomography (OCT) system switchable between single scan mode or multi-scan mode. This is achieved by use of multiple beam splitters to produce multiple OCT beams, but the system still uses a single light source, a single sample arm, and single reference arm to achieve a compact, more cost effective, system. Additionally presented is a spectral domain OCT system with a spectrometer having multiple grating, each providing a different depth and/or resolution imaging capability.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
5.
METHOD AND CONTROL DEVICE FOR ADJUSTING AND/OR CALIBRATING AND/OR MONITORING THE FOCUS VALUE OF AN OPTICAL DEVICE WITH A ZOOM FUNCTION
The invention relates to a method for adjusting and/or calibrating and/or monitoring the focus value of a surgical microscope (1, 40) which comprises at least one objective (2, 3), an image capturing device (5), and a zoom system (8), wherein the surgical microscope (1, 40) is designed to be operated in at least two different zoom settings. The method has the following steps: in at least two different zoom settings, capturing at least one respective image of a fixed object (41) by means of the image capturing device (5) (21); determining a plurality of contrast values on the basis of the focus value (22) using the at least one detected image; and ascertaining at least one target value (23) for at least one parameter for adjusting and/or calibrating the focus value of the surgical microscope (1, 40) using the determined contrast value for the at least two zoom settings.
G02B 7/08 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques pour lentilles avec mécanisme de mise au point ou pour faire varier le grossissement adaptés pour fonctionner en combinaison avec un mécanisme de télécommande
G02B 7/28 - Systèmes pour la génération automatique de signaux de mise au point
G02B 7/36 - Systèmes pour la génération automatique de signaux de mise au point utilisant des techniques liées à la netteté de l'image
An arrangement for OCT-based laser treatment of vitreous floaters. The arrangement for OCT-based laser vitreolysis includes an OCT system, a laser system having a deflection unit, optical elements that couple the OCT system and the laser system, a display unit and a central control and operating unit. The OCT system is configured to localize the floaters, the laser system is configured to destroy the floaters by application of laser pulses and the central control and operating unit is configured to determine apart from the coordinates of the localized floaters also their distance to structures of the eye, to derive exclusion criteria for the treatment, to align the deflection unit of the laser system to these coordinates and to focus and activate the laser system. The present invention relates to an arrangement for the gentle, low risk and painless laser treatment of vitreous floaters, which enables partially or fully automated therapy.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61F 9/009 - Dispositifs auxiliaires destinés à réaliser un contact avec le globe oculaire et un couplage de la lumière laser
7.
PHYSICAL AUGMENTATION OF PATIENT DATA FOR MEDICAL APPLICATIONS
A method for training a machine learning system with an extended set of patient data is described. This method includes measuring patient data and assigning ground truth data, determining the number of data pairs E/A, determining whether the number of data pairs lies below a previously defined training data threshold value, and if this is the case, carrying out the following steps: selecting a physical-optical model; using data pairs E/A in order to determine corresponding second output vectors A″ from input vectors E by means of the relation function R, determining a respective difference vector, modifying the input vectors by an ε-vector; determining third output vectors of the relation function; determining modified output vectors; and training a machine learning system by means of the modified data and the original data.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
8.
METHOD FOR OPERATING A MICROSCOPY SYSTEM, MICROSCOPY SYSTEM, AND CALIBRATION METHOD FOR A MICROSCOPY SYSTEM
A method for operating a microscopy system includes irradiating a region segment of a first region by a light source with light at a first wavelength λ1 and a first luminous intensity L1, determining a substance-specific parameter within the region segment as a response to being irradiated by the light source, and repeating the steps for all region segments within the first region. In addition, the disclosure relates to a microscopy system, and a calibration method for a microscopy system.
An injector for inserting an intraocular lens into a capsular bag of an eye includes an injector body having an injector tip defining an opening. The injector body has a proximal end facing away from the opening and has a distal end. A first piston is directed toward the opening and is configured to contact and displace the intraocular lens. A second piston is operable from outside of the injector and the first piston and the second piston are each configured to be longitudinally displaceable along the injector axis. A handle is operated from outside of the injector and is configured to be coupled to the first piston so that when the pistons are in the decoupling state, the first piston is displaced toward the opening and relative to the second piston by moving the handle.
A computer-implemented method for training a machine learning system to determine an expected offset for a physical postoperative lens position of an intraocular lens to be inserted. The method includes determining a plurality of theoretical positions in the eye of different intraocular lenses to be inserted, the determination including a respective use of a relation and a respective lens-specific constant for the plurality of the theoretical postoperative positions. The method includes: measuring a plurality of postoperative positions of the intraocular lens, with the real postoperative positions being assigned to respective associated theoretical postoperative positions; determining positional differences between theoretical postoperative positions and real postoperative positions; measuring associated ophthalmological biometry data for each tuple; and training a machine learning system to form a trained machine learning model for a prediction of the expected offset for a physical postoperative lens position.
A computer implemented method for determining a refractive power value of an intraocular lens to be inserted is described. The method includes measuring ophthalmological patient data, receiving a target refraction value, determining a first refractive power value of an intraocular lens to be inserted, with the measured ophthalmological patient data and the target refraction value being used as input data, determining, by means of a trained machine learning system, a second refractive power value of the intraocular lens to be inserted, the measured ophthalmological patient data and the received target refraction value being used as input data for the trained machine learning system, and determining the final refractive power value of the intraocular lens to be inserted from the first refractive power value and the second refractive power value by means of an individual boosting factor value.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G06N 20/20 - Techniques d’ensemble en apprentissage automatique
12.
CONTAINER DEVICE HAVING AN OPHTHALMIC INJECTOR HOLDING AN INTRAOCULAR LENS
A container has an ophthalmic injector holding an intraocular lens and a first vessel at least partially filled with a fluid. The intraocular lens is surrounded by the fluid and the first vessel is provided with a lid which closes the first vessel in a fluid-tight manner and which is releasably connected to the first vessel. A second vessel is coupled to the first vessel. A fluid-tight closure is provided between the first vessel and the second vessel, wherein the lid is coupled to the closure by a coupler, and, when the lid is released from the first vessel, the closure is configured, via the coupler, to pass from a closed position to an open position, such that the fluid can flow from the first vessel into the second vessel.
B65D 81/26 - Adaptations pour empêcher la détérioration ou l'altération du contenu; Applications au réceptacle ou au matériau d'emballage d'agents de conservation des aliments, de fongicides, d'insecticides ou de produits repoussant les animaux avec dispositifs pour évacuer ou absorber les fluides, p.ex. s'écoulant du contenu; Emploi de produits empêchant la corrosion ou de dessiccateurs
B65D 77/20 - Fermetures des réceptacles formées après remplissage en appliquant des couvercles ou chapeaux séparés
B65D 81/22 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu fournissant une ambiance spécifique pour le contenu, p.ex. température supérieure ou inférieure à la température ambiante en condition d'humidité ou immergés dans un liquide
B65D 85/38 - Réceptacles, éléments d'emballage ou paquets spécialement adaptés à des objets ou à des matériaux particuliers pour objets particulièrement sensibles aux dommages par chocs ou compression pour appareils optiques de mesure, de calcul ou de commande délicats
13.
LASER SPECKLE REDUCTION IN OPHTHALMIC IMAGES, USING CURRENT PULSE-SHAPING
The eye imaging system for producing images with reduced speckle artifacts may comprise a laser diode for providing a beam of radiation to the eye; a detector for collecting light returning from the eye and generating output signals in response thereto, the detector having a sensor integration time; a driver circuit for applying a modulated drive signal to the laser diode, the modulated drive signal inducing a spectral broadening of the beam of radiation during the sensor integration time. The laser diode may be a single-mode laser designed to operate at a fixed current and wavelength. The drive signal may be modulated by shaping a drive current pulse. The drive signal may be modulated by imposing an RF modulation on a drive current pulse. The drive signal may be further modulated by shaping a drive current pulse.
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
14.
INJECTOR WITH TWO PARTIAL INJECTOR BODIES AND TWO PARTIAL PLUNGERS, AND PACKAGING WITH THE INJECTOR
The invention relates to an injector (1) for introduction of an intraocular lens (13) into the capsular sac of an eye, having an injector body (2), a plunger (3) that is arranged in the injector body in a longitudinally displaceable manner in an insertion direction (11) in which the intraocular lens is to be displaced out of the injector for insertion into the capsular sac, and a joint (8), wherein the injector body has a first partial injector body (4), which has a tip (9) with a tip opening (10), and a second partial injector body (5), which has a proximal end (18) of the injector body and which is attached to the first partial injector body in a pivotable manner by means of the joint, as a result of which the injector body can be pivoted into a usage state and a storage state in which the injector body has, in the insertion direction, a shorter extent than in the usage state, wherein by pivoting the proximal end away from the tip opening, the injector body (2) can be brought from the storage state into the usage state, wherein the plunger has a first partial plunger (6), which is arranged in a longitudinally displacable manner on the first partial injector body, and a second partial plunger (7), which, in the storage state, is spaced apart from the first partial plunger and, in the usage state, is configured to displace the first partial plunger in the insertion direction via a longitudinal displacement of the second partial plunger in the insertion direction.
A61F 2/00 - Filtres implantables dans les vaisseaux sanguins; Prothèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corps; Appareils pour les assujettir au corps; Dispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p.ex. stents
15.
OPHTHALMOLOGICAL COMPOSITION HAVING A PLURALITY OF COMONOMER GROUPS, AND OPHTHALMOLOGICAL LENS
The invention relates to an ophthalmological composition for producing an ophthalmological lens (10), comprising comonomer groups A) to C), at least one comonomer group which is D), E) or a mixture thereof, and at least one crosslinker F). Here: A) denotes at least one (meth)acrylate having at least one aromatic group; B) denotes at least one (meth)acrylate having an aliphatic or non-aromatic cyclic or non-aromatic heterocyclic group; C) denotes at least one (meth)acrylate having at least one hydroxyl group; D) denotes at least one (meth)acrylamide having an aromatic group and having an aliphatic or non-aromatic cyclic or non-aromatic heterocyclic group; and E) denotes a mixture of at least one (meth)acrylamide having two aromatic groups and at least one (meth)acrylamide having two aliphatic and/or non-aromatic cyclic and/or non-aromatic heterocyclic groups. Each of the comonomer groups comprises respectively determined components, based on the total weight of the ophthalmological composition. The invention also relates to an ophthalmological lens (10), which is produced at least in part from such an ophthalmological composition.
G02B 1/04 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES Éléments optiques caractérisés par la substance dont ils sont faits; Revêtements optiques pour éléments optiques faits de substances organiques, p.ex. plastiques
16.
TREATMENT APPARATUS FOR A CATARACT TREATMENT OF AN EYE
A treatment apparatus for a cataract treatment of an eye includes a modular intraocular lens including a first part, which includes a haptic configured to contact a capsular bag of the eye in a region of the equator of the capsular bag and thereby to span the capsular bag, and a second part, which includes an optic body, and has a convergence state, in which the second part contacts the first part, and a spaced-apart state, in which the second part is arranged spaced apart from the first part, a measurement system configured to determine, based on a first measurement, a position of the first part in the eye and in the spaced-apart state of the modular intraocular lens, and a controller configured to determine, based on the position of the first part, a refractive power of the optic body which is to be inserted into the eye.
A61B 3/103 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour la détermination de la réfraction, p.ex. réfractomètres, skiascopes
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Software Medical and surgical apparatus and instruments; surgical laser Medical services, namely ophthalmic services and surgical services in the ophthalmic field
18.
OPHTHALMIC LENS AND METHOD FOR DESIGNING AND FOR PRODUCING SUCH A LENS
An ophthalmic lens (10) with an extended range of focus is made available, the ophthalmic lens (10) comprising a lens body (14) which has a plurality of concentrically arranged annular zones (12). Each of the annular zones (12) has a predetermined refractive power, which differs from the respective refractive powers of the directly adjacent annular zones (12). Each of the annular zones (12) has a topographic relief structure (16), which is designed to effect a phase shift (18) for a partial wave propagating through the respective annular zone (12), wherein the phase shifts (18) in the annular zones (12) at least partially differ from one another and in each case have one of at least five different predetermined values, and wherein each of the annular zones (12) has a predetermined zone area, and the predetermined zone areas of the annular zones (12) at least partially differ from one another. Furthermore, methods for designing and for producing an ophthalmic lens (10) are made available.
A system/method/device for registering two OCT data sets defines multiple image pairs of corresponding 2D representations of one or more corresponding sub-volumes in the two OCT data sets. Matching landmarks in the multiple image pairs are identified, as a group, and a set of transformation parameters are defined based on matching landmarks from all of the image pairs. The two OCT data sets may then be registered based on the set of transformation parameters.
An ophthalmic lens includes a lens body with a predetermined refractive effect and a ring-shaped, diffractive structuring. The ring-shaped, diffractive structuring (4-4) has a waveform in the radial direction which differs from a sinusoidal waveform by an asymmetry and/or a flattening and/or a periodicity, wherein the asymmetry and/or flattening and/or periodicity is constant or changes strictly monotonically over the entire radial curve of the waveform. Further, a method for designing an ophthalmic lens is disclosed.
A planning device for generating control data, a treatment apparatus for refraction correction eye surgery and a method for generating control data for such a treatment apparatus which allows an improved subsequent refraction correction. The planning device includes a calculation processor for defining a cut surface of the cornea for post-treatment, wherein the calculation device is designed such that a change of thickness of the epithelium is taken into account in the calculation, which was caused essentially by a pretreatment.
An apparatus for refractive lens surgery on the human eye, including: a laser device for separating tissue of the eye lens and capsular bag in a focus of pulsed laser radiation, a focus positioning device for setting and adjusting a location of the focus, a measuring apparatus for gathering the relative position of the eye lens and capsular bag, and a control device which reads data from the measuring apparatus and controls the focus positioning device, and which is designed to define and specify a pattern for the focus to the focus positioning device, the pattern separating tissue layers in the eye lens for the purposes of generating an accommodation space for an intralenticular intraocular lens. The accommodation space includes a cutout for a dimensionally-stable lens body of the intraocular lens and a peripheral fastening region for fixing the dimensionally-stable lens body at a single, predetermined, axial position.
An OCT system is constructed on a micro optical bench or semiconductor optical bench. The present OCT system may use free space optics and avoid the use of fiber optics.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/113 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
24.
INTRAOCULAR LENS HAVING A FIRST HAPTIC, WITH TWO ARMS, AND A SECOND HAPTIC
The invention relates to an intraocular lens (1) with an optical body (2) which has an optical axis (3) and a circumferential direction (4) in relation to the optical axis (3), with a first haptic (11) which has a first arm (13), a first longitudinal end (51) of the first arm fastened to the optical body, a second longitudinal end (52) of the first arm and a first relaxation state in which the first arm is free of mechanical stress, and has a second arm (14), a first longitudinal end (51) of the second arm fastened to the optical body, a second longitudinal end (52) of the second arm and a second relaxation state in which the second arm is free of mechanical stress, wherein the first arm has a first point (21) which, in the first relaxation state, has a first distance from the optical axis and, in the first relaxation state, is the point on the first arm at the longest distance from the optical axis, wherein the second arm has a second point (22) which, in the second relaxation state, has a second distance from the optical axis and, in the second relaxation state, is the point on the second arm at the longest distance from the optical axis, wherein the first distance is longer than the second distance, and with a second haptic (12), which is fastened to the optical body and is arranged facing away from the first haptic.
The invention relates to an injector for inserting an intraocular lens (40) into the capsular bag of an eye. The injector (10) has an injector body (11) which has a tip (14) with a tip opening (17), a proximal end (18) facing away from the tip opening (17), an injector body opening (19) facing away from the tip opening (17), and an insertion direction (16) which is oriented from the proximal end (28) to the tip opening (17); a first plunger (21) which is arranged in the injector body (11) in a longitudinally movable manner in the insertion direction (16); and a second plunger (22) which is designed to be introduced into the injector body (11) via the injector body opening (19) and brought into a coupled state of the first plunger (21) and the second plunger (22), said first plunger (21) and second plunger (22) being rigidly coupled together in the insertion direction (16) in the coupled state, wherein the injector (10) has a storage state, in which the second plunger (22) is arranged completely outside of the injector body (11) and next to the injector body (11), and the injector (10) has a latch (30) that has a locking state, in which the latch (30) locks the position of the first plunger (21) in the insertion direction (16), and an unlocking state, in which the first plunger (21) can be moved longitudinally in the injector body (11).
A61M 5/315 - Pistons; Tiges de piston; Guidage, blocage, ou limitation des mouvements de la tige; Accessoires disposés sur la tige pour faciliter le dosage
A61M 5/00 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaire; Accessoires à cet effet, p.ex. dispositifs de remplissage ou de nettoyage, appuis-bras
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61F 9/013 - Procédés ou dispositifs pour la chirurgie de l'œil pour la compensation de la réfraction oculaire
26.
METHOD, COMPUTER PROGRAM AND DATA PROCESSING UNIT FOR PREPARING OBSERVATION OF FLUORESCENCE INTENSITY, METHOD FOR OBSERVING FLUORESCENCE INTENSITY, AND OPTICAL OBSERVATION SYSTEM
What is provided is a method for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3) that comprises object regions (3A-H) that differ from one another in terms of their depth and/or their orientation, wherein the observation is intended to be implemented using an optical observation system (100) using which fluorescence radiation is able to be observed, provided that this has a certain minimum intensity. The method comprises the following steps:
determining the parameter value of at least one parameter which influences the observation of the fluorescence intensity, and
simulating the fluorescence intensity expected for the respective object regions (3A-H) on the basis of the determined parameter value of the at least one parameter and a model of the influence of the at least one parameter on the fluorescence intensity.
What is provided is a method for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3) that comprises object regions (3A-H) that differ from one another in terms of their depth and/or their orientation, wherein the observation is intended to be implemented using an optical observation system (100) using which fluorescence radiation is able to be observed, provided that this has a certain minimum intensity. The method comprises the following steps:
determining the parameter value of at least one parameter which influences the observation of the fluorescence intensity, and
simulating the fluorescence intensity expected for the respective object regions (3A-H) on the basis of the determined parameter value of the at least one parameter and a model of the influence of the at least one parameter on the fluorescence intensity.
Within the scope of the simulation, a minimum concentration of the fluorescent dye is predefined and the fluorescence intensity expected with the minimum concentration is determined for each object region (3A-H) based on the simulation.
What is provided is a method for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3) that comprises object regions (3A-H) that differ from one another in terms of their depth and/or their orientation, wherein the observation is intended to be implemented using an optical observation system (100) using which fluorescence radiation is able to be observed, provided that this has a certain minimum intensity. The method comprises the following steps:
determining the parameter value of at least one parameter which influences the observation of the fluorescence intensity, and
simulating the fluorescence intensity expected for the respective object regions (3A-H) on the basis of the determined parameter value of the at least one parameter and a model of the influence of the at least one parameter on the fluorescence intensity.
Within the scope of the simulation, a minimum concentration of the fluorescent dye is predefined and the fluorescence intensity expected with the minimum concentration is determined for each object region (3A-H) based on the simulation.
Also provided are a computer program, a computer-implemented method, a data processing unit (6) and an optical observation system (100) for preparing the observation of a fluorescence intensity of fluorescence radiation of a fluorescent dye in an observation object (3).
The invention relates to an injector (1) for inserting an intraocular lens (60) into the capsular bag of an eye, comprising an injector body (2) which has a tip (5) with a tip opening (8), a proximal end (9) facing away from the tip opening, and an insertion direction (7) which is oriented from the proximal end to the tip opening; and comprising a telescoping plunger (11) that is arranged in the injector body in a longitudinally movable manner and has multiple sub-plungers (12, 13, 14) and a retracted state, in which the telescoping plunger is retracted, and an extended state, in which the telescoping plunger is extended and in which all of the pairs of sub-plungers are rigidly coupled together in the insertion direction, each pair consisting of two adjacent sub-plungers. One of the sub-plungers is a first sub-plunger (12) which forms the telescoping plunger longitudinal end in the insertion direction in the extended state, and another sub-plunger is a final sub-plunger (14) which forms the telescoping plunger longitudinal end opposite the insertion direction in the extended state. The injector is designed such that the telescoping plunger can be brought from the retracted state into the extended state by moving the final sub-plunger opposite the insertion direction.
A61F 2/00 - Filtres implantables dans les vaisseaux sanguins; Prothèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corps; Appareils pour les assujettir au corps; Dispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p.ex. stents
28.
Treatment apparatus with an optical coherence tomography device, and method for correcting an OCT cross-sectional image
The invention relates to a treatment apparatus having a modular intraocular lens, which comprises a first part having a haptic and a marking, visible in optical coherence tomography, with known dimensions of said marking and a second part having an optics body and which has a convergence state, in which the second part is in contact with the first part, and a spaced-apart state, in which the second part is spaced apart from the first part, having an optical coherence tomography device, which is configured to record, by means of optical coherence tomography, an OCT cross-sectional image which shows the first part arranged in a capsular bag of an eye and which shows dimensions of the marking in the OCT cross-sectional image, and having an evaluation unit which is configured to create a corrected OCT cross-sectional image by transforming coordinates of the OCT cross-sectional image in such a way that dimensions of the marking in the corrected OCT cross-sectional image are closer to the known dimensions of the marking than the dimensions of the marking in the OCT cross-sectional image.
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A microscopy system includes a tracking camera for pose detection of a marker, a device configured to determine a working distance, a movable optical element, the pose of which can be changed to set a capture region of the tracking camera and/or at least two tracking illumination devices, at least one optical element for beam guidance of the radiation generated by the tracking illumination devices, and a controller configured to control the movable optical element and/or the tracking illumination devices, in which the pose of the movable optical element can be set based on the working distance and/or in which an operating mode and/or an illumination region of the tracking illumination devices can be set based on the working distance. In addition, a method for operating a microscopy system is provided.
The present disclosure relates to a microscope and to an imaging method for a microscope. The microscope according to the invention comprises an illumination beam path, which is configured to couple excitation radiation from a light source onto an object to be examined; an optical filter, which is configured to select parts of the excitation radiation; a sensor for detecting an optical property of the excitation radiation; a measurement beam path (90), which is configured to guide a part of the excitation radiation onto the sensor; an observation beam path, which is configured to image radiation emitted by the object; wherein the optical filter is arranged in the beam path between the light source and the sensor, and an image generating means, which is configured to generate an image from the radiation emitted by the object and guided in the observation beam path; wherein the image generating means is configured to use the properties of the filtered excitation radiation that are detected by means of the sensor for the image generation.
G02B 21/16 - Microscopes adaptés pour éclairage ultraviolet
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
31.
METHOD, COMPUTER PROGRAM, AND DATA PROCESSING UNIT FOR CREATING AT LEAST ONE CORRECTION VALUE FOR CORRECTING FLUORESCENCE INTENSITIES IN A FLUORESCENCE IMAGE, AND OPTICAL OBSERVATION SYSTEM
A method for creating at least one correction value for correcting fluorescence intensities in a fluorescence image obtained with an optical observation system includes determining the parameter value of at least one parameter of the optical observation system which influences the observation of the fluorescence intensity, and generating the at least one correction value for correcting the fluorescence intensities in the fluorescence image based on the determined parameter value and the influence of the at least one parameter which influences the observation of the fluorescence intensity on the fluorescence intensities. A parameter of the illumination system serves as the at least one parameter which influences the observation of the fluorescence intensity. Additionally, a computer program, a computer-implemented method, a data processing unit, and an optical observation system for creating at least one correction value for correcting fluorescence intensities in a fluorescence image are provided.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
G06T 5/50 - Amélioration ou restauration d'image en utilisant plusieurs images, p.ex. moyenne, soustraction
32.
REFRACTIVE SURGICAL LASER SYSTEM AND METHOD FOR DETERMINING A DISTANCE BETWEEN A CONTACT GLASS AND A PATIENT'S EYE
A method (300) is provided for determining a distance (1002) between a contact glass (16) and a patient's eye (12). The method (300) comprises capturing (302) image information (700) concerning an optical reflection of the contact glass (16) from a surface of the patient's eye (12) through the contact glass (16), and determining (304) a lateral extent of the optical reflection of the contact glass (16) perpendicular to an optical axis (1000) of the contact glass (16) in the image information (700). The method moreover comprises determining the distance (1002) between the contact glass (16) and the patient's eye (12) along the optical axis (1000) of the contact glass (16) on the basis of the determined lateral extent of the optical reflection of the contact glass (16) in the image information (700).
A microscopy system includes a microscope, a stand configured to mount the microscope and including a drive device configured to move the microscope, a detection device configured to detect a spatial position of a target fastened to a body part or to an instrument, wherein the position detection device includes the target with at least one marker element and an image capture device configured to optically capture the target. The microscopy system further includes at least one control device configured to operate the microscopy system according to the detected position of the target, wherein the position detection device is configured to determine the position of the target by evaluating a two-dimensional image of the image capture device. In addition, a method for operating the microscopy system is provided.
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A system and method for multimodal image acquisition and image visualization, including a surgical-microscopic system with an optical unit and an image sensor and designed for acquiring a time-resolved image signal of a selected field of view of a sample. The system includes an OCT system, which is designed to acquire a time-resolved OCT signal of the selected field of view, a display means designed for the time-resolved display of image data and a control unit. The control unit is configured to ascertain video image data corresponding to the acquired image signal and to present them on the display means, to ascertain a time-resolved OCT image, corresponding at least to a portion of the presented video image data, on the basis of the acquired OCT signal, and to present the OCT image on the display means at the position of the portion.
H04N 13/239 - Générateurs de signaux d’images utilisant des caméras à images stéréoscopiques utilisant deux capteurs d’images 2D dont la position relative est égale ou en correspondance à l’intervalle oculaire
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
The present invention relates to a system for acquiring and visualizing OCT signals, comprising an OCT system and a display means designed for the time-resolved display of image data. The system further comprises a control unit configured to drive the OCT system to acquire a time-resolved OCT signal of a selected field of view of the sample and to determine a time-resolved OCT image on the basis of the acquired time-resolved OCT signal and a specifiable virtual viewing direction and to display the time-resolved OCT image on the display means. The present invention also relates to a corresponding method for acquiring and visualizing OCT signals.
H04N 13/117 - Transformation de signaux d’images correspondant à des points de vue virtuels, p.ex. interpolation spatiale de l’image les positions des points de vue virtuels étant choisies par les spectateurs ou déterminées par suivi du spectateur
H04N 13/207 - Générateurs de signaux d’images utilisant des caméras à images stéréoscopiques utilisant un seul capteur d’images 2D
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
The assembly for laser treatment of ocular opacities consists of: a measurement system for obtaining depth information regarding ocular structures; a laser system; an eye-tracker unit; a display unit; and a control-and-operating unit. According to the invention, the control-and-operating unit is designed to determine, from the depth profiles, the depth of ocular structures relative to the depth of the laser focus, and, in particular for the retina and the capsular bag, to determine a blocked zone for the laser treatment. Furthermore, the control-and-operating unit is designed to generate, at least for the blocked zones of the retina and capsular bag and the laser focus, at least one tag in each case, the characteristic of which corresponds to the particular depth in the eye, in order to display these tags on the display unit and to overlay them with the live image. The invention relates to a partially automated therapy apparatus for laser treatment of ocular opacities in which two-dimensional views of the eye are combined with three-dimensional imaging from the measurement system.
Various examples of the disclosure pertain to remote control of a radiation therapy medical device (91 ) using an application that is executed by a server (95). A digital twin of the radiation therapy medical device (91 ) may be maintained at the application that is executed by the server (95).
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p.ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
Using the present solution, it is possible both to determine optical aberrations and/or the topography and to simultaneously or immediately successively record reference images of an eye. Within the scope of the method, the eye is illuminated with different illumination patterns by means of an illumination unit, and the light reflected by the eye is recorded by a plenoptic camera sensor and evaluated by a control and evaluation unit. According to the invention, the eye is illuminated with different illumination patterns which differ in respect of their intensity distribution and illumination direction, the light reflected by the eye is imaged onto the plenoptic camera sensor and the topography and/or optical aberrations and/or reference images of the illuminated eye are determined from the image data of the plenoptic camera sensor on the basis of the utilized illumination pattern. Even though the solution is especially provided for applications in ophthalmology, it can also be applied in other specialist fields and in industry.
A61B 3/107 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer la forme ou mesurer la courbure de la cornée
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
H04N 23/957 - Caméras ou modules de caméras à champ lumineux ou plénoptiques
H04N 23/56 - Caméras ou modules de caméras comprenant des capteurs d'images électroniques; Leur commande munis de moyens d'éclairage
41.
OPERATING MICROSCOPE HAVING AN ILLUMINATION DEVICE
A surgical microscope includes an optical assembly to image an object plane with a microscope main objective system, through which a first stereoscopic partial beam path with a first optical axis and a second stereoscopic partial beam path with a second optical axis pass. An illumination device includes a light source assembly to provide illumination light in a luminous plane, with a radiant field stop, and an illumination optical unit which at least partially images a luminous object arranged in the luminous plane in the illumination beam path into a luminous image plane located in the microscope main objective system or for the vertical distance z of which from the microscope main objective system on the side facing the object region or the side facing away from the object region, in relation to a focal length f of the microscope main objective system, the following applies: z/f<10%.
The invention relates to an ophthalmological implant (100) with an optically imaging element (110), a digital product identifier (130) being arranged on the optically imaging element. The invention additionally relates to a corresponding method for producing the implant and to a machine reading system (200) for detecting and decoding the digital product identifier. The aim of the invention is to provide an ophthalmological implant and a method for producing same, said method allowing a unique and complete product identifier and a check thereof using simple means at any point in time. This is achieved by an ophthalmological implant with a digital product identifier (130) which is implemented by means of an encoded point grid (135) of identifier points (57), said point grid being machine-readable in the visible light range and having one irregular semi-random character.
An ophthalmic imaging system has a specialized graphical user interface GUI to convey information for manually adjusting control inputs to bring an eye into alignment with the system. The GUI uses color and size changes to indicate axial positioning information of the system relative to a patient's eye. Furthermore, no live feed of the patient's eye is needed. Rather, a graphic indicating the patient's eye is provided and its size is controlled to indicate axial information and to filter out momentary movements of the pupil.
A system, method, and/or device for determinizing a quality measure of OCT structural data and/or OCTA functional data uses a machine learning model trained to provide a single overall quality measure, or a quality map distribution for the OCT/OCTA data based on the generation of multiple features maps extracted from one or more slab views of the OCT/OCTA data. The extracted feature maps may be different texture-type maps, and the machine model is trained to determine the quality measure based on the texture maps.
The invention relates to a planning device for generating control data for a treatment apparatus, which by means of a laser device generates at least one cut surface in the cornea, and to a treatment apparatus having such a planning device. The invention further relates to a method for generating control data for a treatment apparatus, which by means of a laser device generates at least one cut surface in the cornea, and to a corresponding method for eye surgery. The planning device is thereby provided with calculating means for defining the corneal incision surfaces, wherein the calculation means determines the corneal incisions such that after inserting an implant into the cornea, existing refractive errors are counteracted.
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
09 - Appareils et instruments scientifiques et électriques
Produits et services
a software application to provide ophthalmic refractive laser clinics with an overview of their digital marketing impact, assess their strengths and weaknesses, and help to improve their online visibility.
47.
METHOD FOR DETECTING CONTACT OF A PARTICLE, CONSOLE OF AN OPHTHALMIC SURGICAL SYSTEM, AND OPHTHALMIC SURGICAL SYSTEM
The invention relates to a method for detecting contact of a particle (19) that makes contact with a treatment needle (6) of an ophthalmic surgical handpiece (2), wherein the treatment needle (6) can be driven in oscillation by means of an electric drive unit (10), for which purpose an electric drive signal that alternates over time is at least intermittently applied to the electric drive unit (10) by a generator unit (15). According to the invention, in a low-oscillation state of the treatment needle (6), in which the treatment needle (6) oscillates with at most a first oscillation amplitude (A1), an electrical contact signal (35) of the electric drive unit (10) is detected on the basis of a second oscillation amplitude (A2) of the treatment needle (6), wherein the second oscillation amplitude (A2) is greater than the first oscillation amplitude (A1), the detected electrical contact signal is evaluated, and the contact of the particle (19) with the treatment needle (6) is determined on the basis of the evaluation.
The present invention relates to a white-light source and an intraocular illumination device comprising the white-light source. In particular, the invention relates to a white-light source for fiber-based intraocular illumination with light of a controllable, spectrally broad composition, and to an intraocular illumination device having corresponding controllability. A white-light source (100) according to the invention for fiber-based intraocular illumination with light of a controllable spectral composition comprises at least two light sources (10, 20, 30) for the provision of light beams of different colors, preferably with components substantially in the blue, green and red spectral range; wherein the individual light beams are combined to form a combined light beam (W); wherein the white-light source (100) is configured for individual control of the proportions of the individual light beams in the combined light beam (W); wherein at least one of the light sources (10, 20, 30) is a laser-activated remote phosphor, i.e. LARP, light source (90) with a phosphor as a conversion element (98) and a laser diode (92) for exciting the conversion element (98) by means of an excitation radiation (S) emitted by the laser diode (92).
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement
A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
49.
METHOD FOR CENTERING A CONTACT GLASS AND REFRACTIVE SURGICAL LASER SYSTEM
A method for centring a contact glass relative to a patient's eye includes a) providing a fixation light through a contact glass to align the patient's eye glass fixing on the fixation light; b) detecting an image of a light pattern that is imaged on the eye's surface; c) presenting the image over the eye with the contact glass with overlaying of virtual markings, wherein a first marking identifies the central axis of the contact glass and a second marking identifies a reference marking, which is derived from the image of the light pattern as lying on the central axis of the contact glass; d) laterally positioning the contact glass such that a distance between the markings is minimized; and e) establishing the position of the eye at which the second marking is located when the markings adopt the minimized distance and registering the position of the vertex.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 9/008 - Procédés ou dispositifs pour la chirurgie de l'œil utilisant un laser
50.
METHOD FOR A MACHINE LEARNING SYSTEM FOR SURGERY ASSISTANCE
A method for training and using a machine learning system for a differentiation between healthy and diseased tissue during a microsurgical intervention is described. In this case, the method comprises: receiving training data and associated annotation data for training a machine learning system, training the machine learning system, which after training is configured for a prediction of a probability value and a prediction of a trustworthiness value, from which a control signal for a surgery assistance system is derivable, which is usable during a later application during a microsurgical operation, and storing parameter values of the trained machine learning model.
The invention relates to an intraocular lens (1) comprising: an optical body (2) which has an optical axis; and a haptic arm (3) which is attached to the optical body (2), the haptic arm (3) having a radial recess (6) which is formed in a side of the haptic arm (3), which side is positioned outwardly in a radial direction (13) with respect to the optical axis (11). The intraocular lens (1) may comprise a medicament reservoir (4) which is located in the radial recess (6) and which contains a medicament and a through-hole (8) in which the haptic arm (3) is located, the haptic arm (3) having a radial projection (10) which projects inwardly in the radial direction (13) from the remainder of the haptic arm (3) and which is located in the same region as the radial recess (6) in a circumferential direction (14) with respect to the optical axis (11).
The invention relates to a medicament reservoir (4) for an intraocular lens (1), said medicament reservoir comprising: a medicament; a through-hole (8); a first medicament reservoir recess (23) which communicates with the through-hole (8); a first rim (25) which delimits the first medicament reservoir recess (23); a first end face (31) which delimits the through-hole (8); and a second end face (32) which is located opposite the first end face (31) and delimits the through-hole (8), the through-hole (8) having a first longitudinal end (34) in a region of the first end face (31) and a second longitudinal end (35) in a region of the second end face (32), the medicament reservoir (4) having a displacement direction (15) which points from the first longitudinal end (34) to the second longitudinal end (35), and the first medicament reservoir recess (23) being designed such that the through-hole (8) can be accessed via the first medicament reservoir recess (23) from outside the medicament reservoir (4) in a medicament reservoir radial direction (16) relative to the displacement direction (15).
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
The present invention relates to a device for positioning an implant in an eye. The device includes an image recording unit, an image display unit, a control and evaluation unit and an implantation tool. The image recording unit provides images of the target area in the eye. The control and evaluation unit to detects eye structures in the images of the target area, to propose or to select a target region for the implant and to generate navigation data for the introduction of the implantation tool into the target region. The proposed device can be used for positioning implants in any regions of the eye.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
55.
Console for an ophthalmic surgical system for operating a handpiece, and ophthalmic surgical system
A console is for an ophthalmic surgical system for operating a handpiece driven by a work fluid. The work fluid is supplied to a respective work chamber depending on the switching states of work valves. The valves are switched between a switched-on state and a switched-off state by a respective drive unit by respective electrical switching signals being applied to the drive units. Each valve switches from the switched-off switching state into the switched-on switching state during a switch-on time delay and switches from the switched-on state to the switched-off state during a switch-off time delay. The switching signals at least intermittently adopt the switch-on electric potential concurrently during a difference time period if the switch-on delay is longer than the switch-off delay, with a length of time of the difference period arising on the difference between the switch-on delay and the switch-off delay of the valves.
A method for operating a medical radiation therapy arrangement is disclosed, wherein a wound cavity in the patient from which a tumor has been surgically removed is measured three-dimensionally in a reference coordinate system via a surgical microscope of the medical radiation therapy arrangement and/or via a probe-based registration device of the medical radiation therapy arrangement, wherein an x-ray applicator of an intraoperative radiation therapy device of the medical radiation therapy arrangement is selected and/or arranged in the wound cavity on the basis of three-dimensional measurement data generated during the measurement, with the x-ray applicator being navigable in the reference coordinate system. Furthermore, the disclosure relates to a medical radiation therapy arrangement.
An injector for inserting an intraocular lens into the capsular bag of an eye has an injector body; a plunger for displacing the lens out of the injector in an insertion direction, with the lens having an optic body with an optical axis and a rear and a front haptic; a rear mechanism for displacing an optic body distant longitudinal end of the rear haptic onto the optic body via a displacement of the plunger; a front mechanism for displacing an optic body distant longitudinal end of the front haptic along a front trajectory having a front component parallel to the optical axis; and a handle operable from outside of the injector and which has a first catch coupled to the plunger to carry along the plunger in the insertion direction via a longitudinal displacement of the handle and has a second catch to carry along the front displacement mechanism.
The present invention serves for the determination of biometric variables, such as the radii and orientation and the position and shape of the surfaces of the cornea, lens and retina that are optically effective for the eye's vision. The arrangement for the reliable determination of biometric variables of the entire eye is based on optical coherence tomography (OCT), in which the eye is illuminated by a light source via a scanning unit and the components of the light that are scattered back by the boundary surfaces and from the tissue of the eye are recorded by a sensor via an interferometer and are passed on to a control and evaluation unit. The invention provides a device which prevents ambient light from entering the patient's field of view during the determination of biometric variables. The present solution concerns the general area of ophthalmology and serves in particular for the optical determination of the biometry of eyes, but is not restricted to the use of coherence tomography.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
software. medical and surgical apparatus and instruments; surgical laser. medical services, namely ophthalmic services and surgical services in the ophthalmic field.
The invention relates to a method for operating a medical microscope, in particular in the field, with an interchange and/or a misalignment of at least one component of the medical microscope being followed by an identification of the interchanged and/or misaligned at least one component, with required adjustment measures and/or calibration measures being determined in automated fashion using the identified at least one interchanged and/or misaligned component as a starting point, and with the determined required adjustment measures and/or calibration measures being carried out. Furthermore, the invention relates to a medical microscope arrangement.
A method and associated system for operating a robotic visualization system comprising an imaging optical unit and a robotic arm for positioning the imaging optical unit within a surround. The method includes ascertaining a target field of view to be visualized by means of the imaging optical unit. Ascertaining a target pose of the robotic visualization system for capturing an image of the target field of view with a first imaging configuration of the imaging optical unit. Ascertaining a collision probability along a movement path of the robotic visualization system from a current pose to the ascertained target pose using a 3-D model of the surround. Ascertaining an adapted target pose for capturing an image corresponding to the target field of view with a second imaging configuration of the imaging optical unit using the 3-D model of the surround, should the ascertained collision probability exceed a predetermined threshold value.
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
The invention relates to a floor stand for an optical detection device, having a foot part comprising multiple bearing points or a planar standing surface that span a base plane, having a first stand arm which is pivotably connected to the foot part by a first joint on the foot part, and which is connected to a second stand arm by a second joint remote from the foot part, wherein the length of the first stand arm is dimensioned such that the distance between the base plane and the second joint is smaller than the sum of the maximum value for the eye level when seated and the maximum value for the length of the lower leg including the foot when the first stand arm is aligned at 45 degrees in relation to the base plane.
A holding element for a drape for a surgical microscope is provided. The holding element has a holding ring and a recess located in the holding ring for an interface of the surgical microscope. The holding ring has an asymmetrical contour delimiting the recess such that in a condition in which the holding element is fastened to the surgical microscope there is only one possible fastening position of the holding element on the interface of the surgical microscope that corresponds to the contour of the holding ring, in which position an orientation of the holding element relative to the surgical microscope is defined.
The solution serves to greatly reduce the concentration of hazardous aerosols when using appliances (1) for collecting ophthalmic diagnostic information, particularly those appliances in which aerosols are generated and/or distributed by air vortices. According to the invention, the appliance (1) for collecting ophthalmic diagnostic information has a device for reducing the concentration of hazardous aerosols (4), which device is arranged in immediate proximity to the face of the patient (3). In particular, the appliance is a tonometer (2) for short deformation of the eye or includes such a tonometer. The proposed solution is provided in particular for appliances (1) for collecting ophthalmic diagnostic information which are or include a tonometer (2) for short deformation of the eye. However, the solution can also be used for other ophthalmological appliances, but in such cases mainly for the aspiration (10) and filtering (9) of the respiratory air of patients (3) and, optionally, of operators. In particular, the solution can be designed as a chin/forehead support (5) with integrated means for aspiration and filtering of air and can be used as a replacement part for retrofitting of existing appliances.
A61B 3/16 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la pression intraoculaire, p.ex. tonomètres
A61G 13/10 - Tables d'opération; Leurs accessoires - Parties constitutives, détails ou accessoires
66.
METHOD AND APPARATUS FOR ADJUSTING AND CONTROLLING PARAMETERS OF THE ILLUMINATION AREA OF OPHTHALMOLOGICAL DEVICES
A method and device for adjusting and controlling parameters of the illumination area of ophthalmological devices including for example, brightness, color/color temperature, area shape, polarization state. The arrangement according to the invention includes an actuating unit that adjusts the desired lighting parameters, an illumination unit that generates illumination radiation having the desired illumination parameters, a decoupling element that decouples a part of the illumination radiation, a sensor element that analyzes the decoupled part of the illumination radiation and an evaluation unit that evaluates the sensor data and that determines the actual illumination parameters of the illumination radiation. According to an example embodiment of the invention, the sensor element is a spatially resolving image sensor. Embodiments of the invention are provided in particular for adjusting and controlling parameters of the illumination area of ophthalmological devices, but can also be applied to other technical fields, such as microscopy, for example.
A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
67.
SURGICAL MICROSCOPE AND METHOD FOR POSITIONING FILTER ELEMENTS IN A SURGICAL MICROSCOPE
The invention relates to a surgical microscope (1) with a moveable filter support (4.1, 4.2) with at least two filter elements (10.x) arranged on the filter support (4.1), wherein the surgical microscope comprises at least one sensor (13,13.1,13.2) for detecting at least one identifier arranged on the filter support, the identifier comprising at least one marker. The filter support (4.1, 4.2) comprises at least two distinguishable identifiers (14.x) arranged in different positions. The invention also relates to a method for positioning a filter element (10.1,10.2,10.3,10.4) of a filter support (4.1, 4.2) with at least two filter elements (10.1,10.2,10.3,10.4) in a target position in the beam path of a surgical microscope (1), wherein, during a movement of the filter support (4.1, 4.2), the position of an identifier (14.x) uniquely assigned to a filter element (10.1,10.2,10.3,10.4) is detected by a sensor (13,13.1,13.2), and based on the detection of the position of the identifier (14.x), the corresponding filter element (10.1,10.2,10.3,10.4) is positioned in its target position.
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
G02B 7/00 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques
The invention relates to an ophthalmological implant (10) having a main part (12), which comprises a preferably machine-readable product identifier (18), the product identifier (18) consisting to at least some extent of at least one interference dye (22).
The invention relates to an injector (1) for inserting an intraocular lens (5) into the capsular bag of an eye, having an injector body (2), which has a tip (4) with an opening (9), a plunger (3) which is arranged in the injector body (2) so as to be displaceable in a longitudinal direction (16) of the injector (1), and a cushion (6) which is arranged in the longitudinal direction (16) between the opening (9) and the plunger (3), has a shaft (7), which is fastened to the injector body (2), and has a rest position in which the shaft (7) is not extended, wherein the shaft (7) is extensible in such a way that, in the event of an increase of a mechanical tensile stress of the shaft (7), the cushion (6) is displaceable from the rest position as far as the opening, wherein the plunger (3) is configured to push the cushion (6) from the rest position as far as the opening (9) through a displacement of the plunger (3) in the longitudinal direction (16) towards the opening (9).
A control device for controlling and/or regulating an injection flow rate, when injecting a fluid at an injection site between two tissue layers of the human eye with an injection flow rate that increases with time, is described, which comprises a controlling or regulating unit configured to control the injection flow rate in such a way that the injection flow rate increases during the injection for at least 30% of the injection time or during the injection of at least 30% of the injection volume.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
A61F 9/007 - Procédés ou dispositifs pour la chirurgie de l'œil
71.
CREATION OF CURVED CUTS IN THE INDSIDE OF THE EYE CORNEA
A device for isolating a lenticle in the cornea of an eye. The device includes: a laser beam source to emit pulsed laser radiation having a pulse frequency of 1.2 MHz to 10 MHz, a pulse energy of 1 nJ to 200 nJ and a wavelength penetrating the cornea; a beam-forming unit having beam optics with an image field and that bundles pulsed laser radiation into a focus located inside the image field, and which has a maximum diameter of less than 3 μm; a beam-deflection unit shifting the focus in the cornea and inside the image field, the focus moving along a path when the image field is resting; and a control unit to control the source and the beam-forming unit to isolate the lenticle by specifying the path. The lenticle is delimited by a cut surface which is curved with regard to a front surface of the cornea.
The invention relates to a computer-implemented method for biometric analysis of an eye based on image data which is acquired by means of optical coherence tomography. In the method, a probability map is drawn up based on the image data using an algorithm which is based on artificial intelligence, wherein the probability map has a probability value for each pixel of the image data as to whether said pixel is associated with an interface of an eye structure. The eye structure is a lens, optionally a natural lens and/or an artificial lens, and a cornea and/or a retina of the eye.
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 20/70 - RECONNAISSANCE OU COMPRÉHENSION D’IMAGES OU DE VIDÉOS Éléments spécifiques à la scène Étiquetage du contenu de scène, p.ex. en tirant des représentations syntaxiques ou sémantiques
G06V 40/18 - Caractéristiques de l’œil, p.ex. de l’iris
73.
ALIGNMENT IMPROVEMENTS FOR OPHTHALMIC DIAGNOSTIC SYSTEMS
The present application describes the addition of various feedback mechanisms including visual and audio feedback mechanisms to an ophthalmic diagnostic device to assist a subject to self-align to the device. The device may use the visual and non-visual feedback mechanisms independently or in combination with one another. The device may provide a means for a subject to provide feedback to the device to confirm that an alignment condition has been met. Alternatively, the device may have a means for sensing when acceptable alignment has been achieved. The device may capture diagnostic information during the alignment process or may capture after the alignment condition has been met.
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
The invention relates to a tonometer for measuring an intraocular pressure, wherein the examination is carried out without directly contacting the eye. The tonometer according to the invention for measuring intraocular pressure consists of a sound emitter, a surface deformation detector, a control unit, and means for damping noises produced during the measurement for the patient. The term "sound emitter" is to encompass all types of sound, shockwave, and air blast emitters which are suitable for contactlessly generating temporary surface deformations on the eye, said surface deformations being detectable by means of the surface deformation detector. The proposed tonometer is used to measure the intraocular pressure without contacting the eye and is provided in particular for home use. In principle, however, such tonometers are also suitable for clinical use.
A61B 3/16 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la pression intraoculaire, p.ex. tonomètres
75.
ARRANGEMENT FOR OBTAINING DIAGNOSTIC INFORMATION FROM THE EYE
The present invention relates to an arrangement for obtaining diagnostic information from the eye, in particular for assessing a glaucoma. The arrangement consists of a tonometry unit and at least one further unit for obtaining diagnostic information from the eye, and a central control unit. According to the invention, at least the sensor from the tonometry unit and the sensor from the further unit for obtaining diagnostic information are integrated in a joint housing, which rests against the face of the patient at at least 3 points. In this case, the sensors are arranged in such a way in the joint housing that there is no need to reposition this housing between measurements with the tonometry unit and measurements with the further unit for obtaining diagnostic information. The proposed arrangement serves to obtain diagnostic information from the eye and is provided, in particular, for use within an application at home. However, in principle, such arrangements are also suitable for clinical use.
A61B 3/16 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la pression intraoculaire, p.ex. tonomètres
A61B 3/024 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure subjective, c. à d. appareils de d’examen nécessitant la participation active du patient pour la détermination du champ de vision, p.ex. périmètres
The invention relates to a production device for producing an intraocular lens blank, with a first mold half, which has an outer ring, and a second mold half, which have a spacing state, in which the second mold half is arranged outside the outer ring, and a proximity state, in which the second mold half is clamped in the outer ring as a result of inserting the second mold half in an inserting direction, wherein the first mold half has a central region of the first mold half and the second mold half has a central region of the second mold half, wherein the second mold half has a bellows, which extends fully circumferentially around the central region of the second mold half in a circumferential direction with respect to an optical axis of the optical body and has a first bellows portion and a second bellows portion, which is arranged directly outside the first bellows portion in a radial direction with respect to the optical axis.
A61F 9/00 - Procédés ou dispositifs pour le traitement des yeux; Dispositifs pour mettre en place des verres de contact; Dispositifs pour corriger le strabisme; Appareils pour guider les aveugles; Dispositifs protecteurs pour les yeux, portés sur le corps ou dans la main
G02B 3/02 - Lentilles simples ou composées à surfaces non sphériques
G02B 13/24 - Objectifs optiques spécialement conçus pour les emplois spécifiés ci-dessous pour reproduire ou copier à de courtes distances de l'objet
G02B 27/00 - Systèmes ou appareils optiques non prévus dans aucun des groupes ,
The present disclosure relates to a method of medical calibration, including the method steps of: capturing an image representation of a medical marker and of a medical instrument connected therewith; determining a spatial pose of the medical marker on the basis of the image representation; determining a first position of a tracking point of the medical instrument on the basis of the determined spatial pose and on the basis of information relating to a spatial pose relationship between medical marker and tracking point, and determining a second position of the tracking point on the basis of the captured image representation; determining a deviation between the first position and the second position; adjusting the information relating to the spatial pose relationship between medical marker and tracking point on the basis of the determined deviation.
The present disclosure relates to a method of medical navigation including the method steps of: capturing a first image representation of a medical marker in a first perspective; capturing a second image representation of the medical marker in a second perspective; determining a three-dimensional representation of the medical marker on the basis of the first image representation and the second image representation; capturing a third image representation of the medical marker; and determining a spatial pose of the medical marker on the basis of a comparison of the third image representation and the three-dimensional representation of the medical marker. The present disclosure further relates to a medical navigation system, to a computer program and to the use of a three-dimensional representation of a medical marker for registering a medical instrument, a patient and/or a piece of medical equipment.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
80.
METHOD FOR CALIBRATING A STEREOSCOPIC MEDICAL MICROSCOPE, AND MEDICAL MICROSCOPE ARRANGEMENT
The invention relates to a method for calibrating a stereoscopic medical microscope (1), comprising: a) capturing images (20) of at least one three-dimensional calibration object (40) using cameras (3l, 3r) of a stereo camera system (3) of the medical microscope (1); b) generating calibration data (30) on the basis of the captured images (20), the generated calibration data (30) being stored for correction; c) capturing further images (21) of at least one two-dimensional calibration object (41) using the cameras (3l, 3r) of the stereo camera system (3); d) generating further calibration data (31) on the basis of the captured further images (21), the further calibration data (31) being stored for correction. The invention further relates to a medical microscope arrangement (100).
G01C 11/02 - Dispositions de prises de vues spécialement adaptées pour la photogrammétrie ou les levers photographiques, p.ex. pour commander le recouvrement des photos
G03B 35/08 - Photographie stéréoscopique par enregistrement simultané
G06T 7/80 - Analyse des images capturées pour déterminer les paramètres de caméra intrinsèques ou extrinsèques, c. à d. étalonnage de caméra
H04N 13/246 - Générateurs de signaux d’images utilisant des caméras à images stéréoscopiques Étalonnage des caméras
81.
METHOD FOR DETERMINING AN OPTICAL AXIS OF A MAIN OBSERVATION CAMERA OF A MEDICAL MICROSCOPE ASSEMBLY IN A COORDINATE REFERENCE SYSTEM AND MEDICAL MICROSCOPE ASSEMBLY
The invention relates to a method for determining an optical axis (30) of a main observation camera (2) of a medical microscope assembly (50) in a coordinate reference system (22), wherein a detection region (10) is captured by means of a main observation camera (2) and at least partially by an environment camera (3), wherein the environment camera (3) is used for tracking objects and the coordinate system (21) thereof or a coordinate system (23) of an optical marker (13) forms the coordinate reference system (22), wherein a test object (40, 41) is detected at at least one working distance (15), wherein, at the at least one working distance (15), a neutral point (35) of a zoom system (6) of the main observation camera (2) is determined in the coordinate system (21) of the environment camera (2), wherein images (25) of the test object (40, 41) are also captured at different magnifications and evaluated, wherein the optical axis is determined starting from the neutral point (35) determined at the at least one working distance (15), and wherein at least one item of information (33) describing the determined optical axis (30) in the coordinate reference system (22) is generated and provided. The invention also relates to a medical microscope assembly (50).
The invention relates to a method for operating a stereoscopic medical microscope, wherein deteriorated and/or invalid calibration data are recognized, wherein for this purpose mutually corresponding image representations of at least one feature arranged in capture regions of cameras of a stereo camera system of the medical microscope are captured by means of the cameras, the captured image representations are evaluated by means of feature-based image processing, wherein the at least one feature is recognized in this case in the captured image representations and a misalignment and/or a decalibration of the cameras of the stereo camera system are/is recognized on the basis of the at least one feature recognized; and wherein at least one measure is carried out depending on an evaluation result. Furthermore, the invention relates to a medical microscope.
G06T 7/80 - Analyse des images capturées pour déterminer les paramètres de caméra intrinsèques ou extrinsèques, c. à d. étalonnage de caméra
G06V 10/24 - Alignement, centrage, détection de l’orientation ou correction de l’image
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p.ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersections; Analyse de connectivité, p.ex. de composantes connectées
G06V 10/74 - Appariement de motifs d’image ou de vidéo; Mesures de proximité dans les espaces de caractéristiques
83.
METHOD FOR ADJUSTING AND/OR CALIBRATING A MEDICAL MICROSCOPE AND MEDICAL MICROSCOPE
The invention relates to a method for adjusting and/or calibrating a medical microscope, the following being implemented for at least one observer beam path of the medical microscope: capturing respective image representations of an object at different magnification levels of a zoom optical unit, and determining a zoom center using the captured image representations as a starting point, and i) capturing respective further image representations at different axis positions of at least one linear or rotational movement axis of the medical microscope, a rotation of the capture device relative to the at least one linear or rotational movement axis being determined using the captured further image representations as a starting point, and/or ii) capturing respective further image representations of the object in different focal planes and/or at different working distances in the case of an off-centered imaging optical unit, a rotation of the capture device being determined using the captured further image representations as a starting point, and a reference marking being determined using the determined zoom center and the determined rotation as a starting point and being provided for adjustment and/or calibration purposes. Further, the invention relates to a medical microscope.
Various examples relate to techniques for recording, in the context of surgery carried out on a patient, measured data with depth resolution so that a transformation rule can be defined based on these data which mediates between images recorded by means of a robotic visualization system, a surgical microscope, for example, and pre-surgery volume image data.
An intraocular lens has an optic body, a haptic element mounted on the optic body and having a haptic curvature and a plurality of recesses on the side of the haptic element facing the optic body, a first actuator configured to reversibly change the haptic curvature of the haptic element such that the haptic element is moved away from the optic body from a rest position, a brace arm mounted on the optic body and the longitudinal brace arm end which is configured to be provided a recess when the haptic element is in the rest position, and a second actuator configured to reversibly change, with a change in a property of the second actuator, a brace arm curvature of the brace arm such that the recess in which the longitudinal brace arm end is to be provided can be adjusted with the property of the second actuator.
A plunger for an injector to inject an intraocular lens into the capsular bag of an eye has a deformable cushion and a contact surface with a cutout in which an imaginary reference point is arranged. The plunger has two points groups, each having a design point arranged on an outer contour, an inner contour point arranged on an inner contour, and a reference point. For each of the point groups, the distance from the design point to a circle or a closed curve is equal to the distance from the inner contour point to the reference point, the design point, the inner contour point and the reference point lie on a straight line, and the inner contour point lines between the design point and the reference point. The distance from the inner contour point to the reference point is different for at least two of the point groups.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Viscoelastic ophthalmological liquids used during eye surgery
88.
Tissue adhesive for use in a treatment method in which an ophthalmological implant is implanted in a human or animal patient, and ophthalmological implantation system
The disclosure relates to a tissue adhesive for use in a treatment method in which an ophthalmological implant is implanted in a human or animal patient and the ophthalmological implant is connected, at least partially in an integrally bonded manner, to eye tissue of the patient via the tissue adhesive. The disclosure also relates to an ophthalmological implantation system including an ophthalmological implant for implantation in a human or animal eye and to a tissue adhesive via which the ophthalmological implant is connectable, at least partially in an integrally bonded manner, to eye tissue of the patient.
A61K 31/337 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à quatre chaînons, p.ex. taxol
A61K 31/78 - Polymères contenant de l'oxygène d'acide acrylique ou de ses dérivés
A61K 38/18 - Facteurs de croissance; Régulateurs de croissance
A61L 24/04 - Adhésifs ou ciments chirurgicaux; Adhésifs pour dispositifs de colostomie contenant des matériaux macromoléculaires
89.
MEDICAL OPTICAL SYSTEM, DATA PROCESSING SYSTEM, COMPUTER PROGRAM, AND NON-VOLATILE COMPUTER-READABLE STORAGE MEDIUM
The invention relates to a medical optical system. The medical optical system comprises: —a microendoscope (3) for capturing histological images, each of which displays a microscopic tissue section (16) of a macroscopic tissue region (15) with a tumor (23); and—a classification device (31) for classifying the macroscopic tissue sections (16) displayed in the histological images as at least one respective tissue section that represents the tumor (23) or a tissue section that represents healthy tissue and for outputting a classification result for each classified microscopic tissue section (16). The medical optical system additionally comprises a combination device (37) which generates a macroscopic classification image (43) by combining the classification results, said classification image representing the location of the tumor (23) in the macroscopic tissue region (15).
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
A61B 1/04 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision
A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p.ex. DICOM, HL7 ou PACS
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p.ex. pour des analyses d’échantillon de patient
Equipment and methods for refractive surgery, including for keratoplasty. The invention describes equipment and methods for the production and implantation of a lamella of a tissue or material for the purpose of correcting a corneal geometry at maximum precision that is thus improved in relation to the prior art. The invention facilitates restoration of normal corneal geometry together with optical functionality of the cornea which is improved in relation to the prior art. A planning device, a treatment system and a planning method are designed to couple a device coordinate systems of the laser devices involved and characterization devices by application of registration and to uniquely register the supplied measurement data for generating the lamella to be implanted to the device coordinate systems by a specific, defined edge geometry of a blank from which the lamella is produced, and by the lamella, and by additional system and method aids.
The present invention relates to a stent implant for treating glaucoma by means of intraocular fluid drainage from the anterior chamber, preferably in the suprachoroidal space. The stent implant according to the invention is designed to bring about a change in shape after being inserted into the eye, during which change the width and/or thickness or the flow cross-section is increased by more than 20%, preferably more than 200%, and particularly preferably by more than 400%, at at least one point of the stent implant. In the case of intraocular fluid drainage from the anterior chamber into the suprachoroidal space, a cyclodialysis cleft which may open can therefore be at least largely or completely closed. The proposed stent implant is provided in particular for intraocular fluid drainage into the suprachoroidal space. With appropriate adjustments, the stent implant can also be applied in trabecular, uveoscleral, uveolymphatic and subconjunctival applications for intraocular fluid drainage from the anterior chamber. Said implant can even be used for direct intraocular fluid discharge from the anterior chamber onto the surface of the eye.
A surgical microscope for visualizing a tissue region contains an illumination device with a light source and an illumination beam path for illuminating an object region with an object plane and an observation device having an observation beam path for imaging the object region with the object plane into an observation plane. A first polarizer can be coupled into the illumination beam path and is suitable for polarizing the illumination light in a first orientation. A polarizer, which can be coupled into the observation beam path, has a second orientation at an angle between 80° and 100° relative to the first orientation. In a first mode, the light source emits illumination light in a first wavelength range between 450 nm and 550 nm, the first polarizer is coupled into the illumination beam path, and the second polarizer is coupled into the observation beam path.
A61B 90/20 - Microscopes chirurgicaux caractérisés par des aspects non optiques
A61B 90/30 - Dispositifs pour éclairer une zone chirurgicale, les dispositifs ayant une corrélation avec d’autres dispositifs chirurgicaux ou avec une intervention chirurgicale
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
94.
METHOD FOR THE PROVISION OF A TARGET BEAM GUIDANCE PATH AND OPTHALMIC LASER SYSTEM
The invention relates to a method for providing a target beam guidance path (200) for deflecting a laser beam (14) of an opthalmological laser system (10) by means of an adjusting device (16). The method comprises establishing an adjustment section (2002) of the target beam guidance path (202) in which the adjusting device (16) is transferred from a stationary position at a stationary point into continuous motion for the purpose of beam guidance of the laser beam (14), and in which there is no irradiation by the laser beam (14) of an object to be treated. The method also comprises establishing an irradiation section (2004) of the target beam guidance path (200), which is adjacent to the adjustment section (2002), in which the laser beam (14) performs a continuous movement by means of the adjusting device (16), and in which there is an irradiation by the laser beam (14) of an object to be treated. There is also the establishing of a length and/or duration of the adjustment section (2002) and/or of a spacing of the start of the irradiation section (2002) from the stationary point of the adjustment section (2002), in such a way that a deviation of an actual beam guidance path (202) from the established target beam guidance path (200) accompanying the transfer of the adjusting device (16) from stationary into the continuous motion is less than a predetermined threshold value in the entire irradiation section (2004). The invention also relates to a control unit (22), an opthalmological laser system (10), a computer program product and a computer-readable storage medium.
The present System / Method / Device uses a (e.g., self-use) OCT system for personalized monitoring of wet AMD patients. A patient self-administers an OCT scan, which is then automatically analyzed and notifies the patient and/or a designated authorized doctor/technician if there is a need for application of medication or professional medical attention.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
An ultraviolet laser-based (UVL) laser vision correction (LVC) system, a contact interface and a contact interface system for such a UVL-LVC system. The invention facilitates a coupling and affixation between the patient's eye and the UVL-LVC system by application of a contact interface for the purposes of preventing eye movements when using UVL-LVC systems. The invention includes a UVL-LVC system with a base unit and an application arm which has a contact interface adapter on an application part of the application arm, to which a contact interface is affixable, the contact interface being usable to be to affix a patient's eye to the UVL-LVC system. The contact interface may have a conical wall and a suction ring but not a lens element, and optionally has an access opening or a corresponding contact interface system made of a contact interface adapter and a contact interface.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Software application to provide ophthalmic refractive laser clinics with an overview of their digital marketing impact, assess their strengths and weaknesses, and help to improve their online visibility
An ophthalmo-surgical injector includes an injector body, a tip with which an intraocular lens can be pressed out of the injector, a first plunger mounted longitudinally displaceably on the injector body and having a first projection, a shaft rotatably mounted in the injector body and having a first guide and a second guide which are each wound about the shaft, and a second plunger mounted longitudinally displaceably on the injector body and having a second projection. The first projection engages in the first guide, such that the first plunger is configured to effect, with a longitudinal displacement of the first plunger, a rotation of the shaft about a longitudinal axis of the injector body, and the second projection engages in the second guide, as a result of which the shaft is configured to effect, with the rotation effected by the first plunger, a longitudinal displacement of the second plunger.
A method for operating a microscopy system and to a microscopy system are provided. A pivot point is defined, wherein the microscopy system is operated such that a microscope of the microscopy system moves at a constant distance around the pivot point, wherein a reference surface is determined, wherein an intersection of an optical axis of the microscope and the reference surface is determined as the pivot point, wherein the pose of the reference surface is defined in a focal position-independent reference coordinate system and the pivot point is determined as the intersection of the optical axis with the thus defined reference surface in the reference coordinate system.
A method for aligning a system for laser-based ametropia correction relative to a patient's eye to be treated is disclosed. Predefined pre-operative measurement data which characterize at least predetermined structures of the patient's eye is provided. The predetermined structures include a part of the patient's eye to be treated. In addition, the method includes measuring at least one part of the predetermined structures of the patient's eye using an OCT system immediately before and/or during treatment for ametropia correction of the patient's eye and providing OCT measurement data, and comparing the OCT measurement data and the predefined pre-operative measurement data and preparing comparative data. The method also includes ascertaining a position and/or orientation of the part of the patient's eye to be treated relative to the system and aligning the system relative to the patient's eye using the ascertained position and/or orientation of the part of the patient's eye.
