COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Billy, Emmanuel
Porthault, Hélène
Abrégé
The invention relates to a method for opening and discharging an electrochemical generator (10) comprising a negative electrode containing lithium or sodium and a positive electrode optionally containing lithium or sodium, the method comprising the following successive steps: - opening the electrochemical generator (10) in a cutting zone, with a cutting element (20), preferably having an electrical resistance greater than 100 mΩ, the electrochemical generator being opened while spraying the cutting zone with a first solution (100), - discharging the electrochemical generator by partially or completely submerging the electrochemical generator (10) in a second solution (200).
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Serp, Jérôme
Abrégé
The invention relates to a device (10) comprising: - a component (20) configured to contain or circulate a solution, the component (20) having a wall (21) made of steel or a nickel-based alloy comprising chromium, - a solution (30), in contact with the wall (21), comprising a mixture of molten chloride salts, the solution also comprising Ti2+ions and Ti3+ions, the Ti3+/Ti2+ ratio being between 20/80 and 70/30.
C23F 11/18 - Inhibition de la corrosion de matériaux métalliques par application d'inhibiteurs sur la surface menacée par la corrosion ou par addition d'inhibiteurs à l'agent corrosif dans d'autres liquides au moyen d'inhibiteurs inorganiques
C23F 13/00 - Moyens pour empêcher la corrosion des métaux par protection anodique ou cathodique
F24S 20/20 - Collecteurs de chaleur solaire pour recevoir de l’énergie solaire concentrée, p.ex. récepteurs pour centrales électriques solaires
F24S 80/20 - Fluides vecteur spécialement adaptés pour les collecteurs de chaleur solaire
G21C 1/03 - Réacteurs de fission rapides, c. à d. réacteurs n'utilisant pas de modérateur refroidis par un réfrigérant non nécessairement pressurisé, p.ex. réacteurs du type piscine
G21C 3/54 - Sels fondus, compositions oxydes ou hydroxydes
G21C 17/022 - Dispositifs ou dispositions pour la surveillance du réfrigérant ou du modérateur pour la surveillance de réfrigérants ou de modérateurs liquides
G01N 27/00 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques
G01N 17/02 - Systèmes de mesure électro-chimique de l'action due aux intempéries, de la corrosion ou de la protection contre la corrosion
G01N 27/30 - Composants de cellules électrolytiques Électrodes, p.ex. électrodes pour tests; Demi-cellules
C23F 15/00 - Autres méthodes pour prévenir la corrosion, l'entartrage ou les incrustations
C25C 3/28 - Production, récupération ou affinage électrolytique de métaux par électrolyse de bains fondus du titane, du zirconium, de l'hafnium, du tantale ou du vanadium du titane
C09K 5/02 - Substances qui subissent un changement d'état physique lors de leur utilisation
C09K 5/12 - Substances fondues, c.à d. substances solides à température ambiante, p.ex. métaux ou sels
3.
PROCESS FOR THE PURIFICATION OF RUTHENIUM WITH RESPECT TO TECHNETIUM AND METAL IMPURITIES IN AN AQUEOUS NITRIC ACID SOLUTION
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Andreiadis, Eugen
Moreau, Ella
Abrégé
The invention relates to a process for purifying ruthenium from an aqueous nitric acid solution in which same is present together with technetium and metal impurities, at a concentration at least 10 times lower than that of the technetium. It also relates to a process for producing ruthenium-97 from a technetium-99 target which has been been proton-irradiated beforehand, which process comprises the implementation of the purification process. Application: production of ruthenium-97-based radiopharmaceuticals used in nuclear medicine for the diagnosis of cancer by imaging and the treatment thereof by targeted radiotherapy.
The invention relates to a method for producing hydrogen by electrochemically reforming an alcohol. This method comprises electrolyzing alcohol in an electrolytic cell comprising an anode, an electrolyte and a cathode, and is characterized in that at least part of the outer surface of the anode comprises one or more radioactive platinoids selected from among palladium, ruthenium and rhodium, these one or more radioactive platinoids being derived from an acidic aqueous solution containing fission products from a spent nuclear fuel.
C25B 1/04 - Hydrogène ou oxygène par électrolyse de l'eau
B01J 23/40 - Catalyseurs contenant des métaux, oxydes ou hydroxydes métalliques non prévus dans le groupe des métaux nobles des métaux du groupe du platine
C25B 3/07 - Composés contenant au moins un atome d’oxygène
C25B 11/052 - PROCÉDÉS ÉLECTROLYTIQUES OU ÉLECTROPHORÉTIQUES POUR LA PRODUCTION DE COMPOSÉS ORGANIQUES OU MINÉRAUX, OU DE NON-MÉTAUX; APPAREILLAGES À CET EFFET Électrodes; Leur fabrication non prévue ailleurs caractérisées par le matériau Électrodes comportant des électro-catalyseurs sur un substrat ou un support Électrodes comportant un substrat et un ou plusieurs revêtements électro-catalytiques
B01J 37/34 - Irradiation ou application d'énergie électrique, magnétique ou ondulatoire, p.ex. d'ondes ultrasonores
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Billy, Emmanuel
Porthault, Hélène
Abrégé
A method for opening an electrochemical generator (10) comprising a negative electrode (20) containing lithium or sodium and a positive electrode (30) optionally containing lithium or sodium, the method comprising the following successive steps: a) immersing the electrochemical generator (10) in a solution comprising an inert liquid and, optionally, a redox species, referred to as an oxidising redox species, capable of being reduced on the negative electrode so as to discharge the electrochemical generator; b) opening the electrochemical generator in the solution with a cutting element (100) that has an electrical resistance between 1 mΩ and 1 kΩ, and preferably between 5 mΩ and 100 Ω.
H01M 6/52 - Récupération des parties utiles des éléments ou batteries usagés
H01M 8/008 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Éléments à combustible; Leur fabrication Élimination ou recyclage des éléments à combustible
H01M 10/54 - Récupération des parties utiles des accumulateurs usagés
6.
METHOD FOR DISSOLVING A POSITIVE ELECTRODE MATERIAL
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Billy, Emmanuel
Abrégé
The invention relates to a method for dissolving a positive electrode material of a battery comprising a step during which the positive electrode material, comprising lithium and optionally cobalt and/or nickel, is submerged in an acid solution having a pH between 0 and 4, the acid solution containing either manganese ions or hydrogen peroxide, by means of which the lithium and optionally the cobalt and/or nickel is dissolved, and the manganese ions are selectively precipitated in the form of manganese oxyhydroxide.
The invention relates to a PSMA-targeting conjugate or a pharmaceutically acceptable salt which may be used either for preparing a radiopharmaceutical or, once labeled with a radionuclide, as a radiopharmaceutical. The conjugate is of formula (I): A1-L1-Ch -L2-A2(I) wherein: Ch is a chelator, L1and L2, identical or different, are a linker whereas A1and A2, identical or different, are an urea-based PSMA ligand. The invention also relates to the uses thereof.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Billy, Emmanuel
Abrégé
The invention relates to a method for securing an electrochemical generator (10) comprising a negative electrode (20) containing lithium or sodium and a positive electrode (30), the method comprising the following successive steps: (a) immersing an electrochemical generator (10) in an ionic liquid solution (100) containing a solvent ionic liquid and, optionally, a redox species, referred to as the oxidising species, capable of being reduced on the negative electrode so as to discharge the electrochemical generator; (b) opening the electrochemical generator with an electrically insulative element, opening being performed in the ionic liquid solution.
H01M 4/02 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif
9.
METHOD FOR DISCHARGING AN ELECTROCHEMICAL GENERATOR
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Billy, Emmanuel
Brun-Buisson, David
Guilpain, Mathilde
Abrégé
Disclosed is a method for discharging an electrochemical generator (10) comprising a negative electrode (20) containing lithium or sodium and a positive electrode (30), the method comprising a discharging step during which the electrochemical generator (10) is brought into contact with an ionic liquid solution (100) containing a solvent ionic liquid and an electrically conductive powder so as to discharge the electrochemical generator (10).
C22B 7/00 - Mise en œuvre de matériaux autres que des minerais, p.ex. des rognures, pour produire des métaux non ferreux ou leurs composés
B09B 3/00 - Destruction de déchets solides ou transformation de déchets solides en quelque chose d'utile ou d'inoffensif
H01M 4/02 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif
10.
CONJUGATE OR ITS SALT COMPRISING A GASTRIN-RELEASING PEPTIDE RECEPTOR ANTAGONIST AND USES THEREOF
ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS (France)
Inventeur(s)
Gasser, Gilles
Cowell, Joseph
Mindt, Thomas
Brandt, Marie
Felder, Patrick S.
Tekin, Volkan
Abrégé
The invention relates to a diaza-18-crown-6 derivative having formula (I): wherein: B is a moiety for a covalent bonding reaction; the two A are identical to each other and are a group of formula (II): where: n = 0 to 4; X1, X2, X3, X4and X5are N, a -CH group or a -CR group wherein R is a -P(O)(OR1)(OR2), -P(O)R1(OR2), -P(O)R1R2, -P(S)(SR1)(SR2), -P(S)R1(SR2) or -P(S)R1R2group in which R1and R2144 alkyl group, provided that no more than two of X1, X2, X3, X4and X5are N and no more than one of X1, X2, X3, X4and X5 is a -CR group. The invention also relates to a conjugate comprising the diaza-18-crown-6 derivative covalently bonded to a targeting moiety for biological cells, a chelate comprising radium chelated by the conjugate, and to uses of the diaza-18-crown-6 derivative, the conjugate and the chelate.
C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
C07D 273/08 - Composés hétérocycliques contenant des cycles comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle, non prévus par les groupes comportant deux atomes d'azote et plusieurs atomes d'oxygène
C07F 3/00 - Composés contenant des éléments des groupes 2 ou 12 de la classification périodique
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Billy, Emmanuel
Barthelemy, Sandrine
Abrégé
Disclosed is a method for selectively separating a carbon-containing material from a mixture comprising a positive electrode and a negative electrode originating from fuel cells and/or electrochemical batteries, the method comprising the following successive steps: a) providing a mixture comprising a positive electrode and a negative electrode, each electrode comprising a current collector, an active material and a binder, the active material of the negative electrode being a carbon-containing material, preferably graphite, b) bringing the mixture comprising the positive electrode and the negative electrode into contact with a separating solution, in the presence of ultrasound, the separating solution comprising a solvent and possibly additives, until the carbon-containing material is selectively separated from the current collector of the negative electrode, the active material of the positive electrode remaining joined to the current collector of the positive electrode.
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (France)
ORANO (France)
Inventeur(s)
Billy, Emmanuel
Abrégé
Disclosed is a method for recycling at least one electrode, comprising the following consecutive steps: a) providing at least one electrode comprising a current collector, an active material and, optionally, a binder, b) immersing the at least one electrode in an ionic liquid solution comprising a solvent ionic liquid, in the presence of ultrasound, whereby the active material, and if applicable the binder, is separated from the current collector.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
H01M 10/54 - Récupération des parties utiles des accumulateurs usagés
14.
PROCESS FOR SITE-SPECIFIC MODIFICATION OF AN ANTIBODY
The present application concerns a process for preparing a site-specific bioconjugated antibody with a metal Chelator, the bionconjugated antibody and its use in nuclear medicine.
The invention relates to a method for preparing one or more generators with a high radium-228 content from an aqueous solution comprising thorium-232 and radium-228. The generator(s) can be used, in particular, for producing thorium-228, from which radium-224, then lead-212 and bismuth-212 can be obtained. The method and the generator(s) that it can be used to prepare are therefore applicable, in particular, in the manufacture of radiopharmaceuticals made from lead-212 or bismuth-212, which can be used in nuclear medicine and, in particular, in targeted alpha radiotherapy for the treatment of cancers.
G21G 4/08 - Sources radioactives autres que les sources de neutrons caractérisées par des aspects de leur structure spécialement adaptées aux applications médicales
G21G 1/00 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p.ex. production d'isotopes radioactifs
16.
METHOD FOR TRANSFERRING A RADIOISOTOPE BETWEEN TWO STATIONARY PHASES CONTAINED IN TWO CHROMATOGRAPHY COLUMNS
The invention relates to a method for transferring a radioisotope that is attached to a first stationary phase contained in a first chromatography column to a second stationary phase contained in a second chromatography column, in order to fix the radioisotope to the second stationary phase, wherein the radioisotope is selected from the radioactive isotopes of thorium, radium, lead, bismuth and uranium. Said method comprises at least the following steps: a) eluting the radioisotope from the first stationary phase with an aqueous solution A1 comprising an agent complexing the radioisotope, whereby an aqueous solution A2 is obtained which comprises complexes of the radioisotope; b) dissociating the complexes of the radioisotope present in the aqueous solution A2 by modifying the pH of the aqueous solution A2, whereby an aqueous solution A3 comprising the decomplexed radioisotope is obtained; c) loading the second stationary phase with the aqueous solution A3; and d) carrying out at least one washing of the second stationary phase with an aqueous solution A4.
G21G 4/08 - Sources radioactives autres que les sources de neutrons caractérisées par des aspects de leur structure spécialement adaptées aux applications médicales
C07B 59/00 - Introduction d'isotopes d'éléments dans les composés organiques
G21G 1/00 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p.ex. production d'isotopes radioactifs
17.
METHOD FOR PRODUCING LEAD-212 FROM AN AQUEOUS SOLUTION COMPRISING THORIUM-228 AND ITS DESCENDANTS
The invention relates to a method for producing x-ray very high purity lead-212 from an aqueous solution comprising thorium-228 and its descendants. Applications: manufacture of radiopharmaceuticals based on lead-212, which are useful in nuclear medicine and, in particular, in targeted alpha radiation therapy for the treatment of cancers.
G21G 1/00 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p.ex. production d'isotopes radioactifs
The present invention concerns a process for producing a daughter radionuclide from a parent radionuclide comprising the purification of the daughter radionuclide on a chromatography column, as well as the apparatus for carrying out such process.
G21G 1/00 - Dispositions pour la conversion des éléments chimiques par rayonnement électromagnétique, radiations corpusculaires ou bombardement par des particules, p.ex. production d'isotopes radioactifs