Introduced here is an attachable unit that connects to a base unit through a snap-fitting mechanism. The attachable unit can include a top housing structure and a bottom housing structure that are ultrasonically welded together. The top housing structure can include the toe portion that is integral with remaining portions of the top housing structure, where the toe portion is configured to provide the snap-fit with the base unit.
H05K 7/00 - CIRCUITS IMPRIMÉS; ENVELOPPES OU DÉTAILS DE RÉALISATION D'APPAREILS ÉLECTRIQUES; FABRICATION D'ENSEMBLES DE COMPOSANTS ÉLECTRIQUES - Détails de construction communs à différents types d'appareils électriques
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
2.
Combined Compression and Feature Extraction Models for Storing and Analyzing Medical Videos
A method of compressing and detecting target features of a medical video is presented herein. In some embodiments, the method may include receiving an uncompressed medical video comprising at least one target feature, compressing the uncompressed medical video to generate a compressed medical video based on a predicted location of the at least one target feature using a first pretrained machine learning model, and detecting the location of the at least one target feature of the compressed medical video using a second pretrained machine learning model. In some embodiments, the first pretrained machine learning model and the second pretrained machine learning model may be trained in tandem using domain-specific medical videos.
H04N 19/50 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage prédictif
G06T 7/73 - Détermination de la position ou de l'orientation des objets ou des caméras utilisant des procédés basés sur les caractéristiques
G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06V 20/40 - RECONNAISSANCE OU COMPRÉHENSION D’IMAGES OU DE VIDÉOS Éléments spécifiques à la scène dans le contenu vidéo
H04N 19/136 - Caractéristiques ou propriétés du signal vidéo entrant
H04N 19/147 - Débit ou quantité de données codées à la sortie du codeur selon des critères de débit-distorsion
H04N 19/184 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage adaptatif caractérisés par l’unité de codage, c. à d. la partie structurelle ou sémantique du signal vidéo étant l’objet ou le sujet du codage adaptatif l’unité étant des bits, p.ex. de flux vidéo compressé
H04N 19/436 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques - caractérisés par les détails de mise en œuvre ou le matériel spécialement adapté à la compression ou à la décompression vidéo, p.ex. la mise en œuvre de logiciels spécialisés utilisant des dispositions de calcul parallélisées
3.
SYSTEMS AND METHODS FOR BIOMARKER DETECTION IN DIGITIZED PATHOLOGY SAMPLES
One example method for biomarker detection in digitized pathology samples includes receiving a plurality of image patches corresponding to an image of a pathology slide having a hematoxylin and eosin-stained (“H&E”) stained sample of tissue, each image patch representing a different portion of the image; for each image patch, determining, using a first trained machine learning (“ML”) model, a patch biomarker status; and determining, using a second trained ML model, a tissue sample biomarker status for the sample of tissue based on the patch biomarker statuses of the image patches.
A machine learning framework for breast cancer histologic grading is described herein. In an example, a method involves accessing a whole slide image of a specimen. The image is processed using a first, second, third, and fourth machine learning process. A first output of the first machine learning process indicates portions of the image predicted to depict tumor cells. A second output of the second machine learning process corresponds to a mitotic count predicted score for a mitotic count depicted in the image, a third output of the third machine learning process corresponds to a nuclear pleomorphism predicted score for nuclear pleomorphism depicted in the image, and a fourth output of the fourth machine learning process corresponds to a tubule formation predicted score for tubule formation depicted in the image. A combined score of a predicted histologic grade of a disease in the image is generated based on the outputs.
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
Described herein is a front-end for a neural recording system that boosts input impedance of the front-end circuit. The front-end includes an amplifier and two choppers. A first input terminal of the first chopper may be coupled to a first output terminal from one or more signal sensors. A first input terminal of the second chopper may be coupled to a second output terminal from the signal sensors. A second input terminal of the first chopper may be coupled to a first output terminal of a feedback subsystem. A second input terminal of the second chopper may be coupled to a second output terminal of the feedback subsystem. The output terminals of each chopper may each be coupled to a different capacitor such that after switching, the voltage of each capacitor remains substantially the same, improving the input impedance of the circuit.
H03F 3/38 - Amplificateurs de courant continu, comportant un modulateur à l'entrée et un démodulateur à la sortie; Modulateurs ou démodulateurs spécialement conçus pour être utilisés dans de tels amplificateurs
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Laboratory services for testing wastewater for pathogens; providing information and analysis of epidemiological information and data pertaining to pathogens in wastewater
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Wearable devices for the detection, monitoring, and
management of health and physiological data, not for medical
use, namely, wearable activity and biometric data trackers,
and wearable computers in the nature of smartwatches not for
medical use. Wearable devices for the detection, monitoring, and
management of health and physiological data, namely,
wearable activity and biometric data trackers, wearable
computers in the nature of smartwatches, and medical
apparatus and instruments for monitoring vital signs, blood
properties and respiratory properties and events; all the
foregoing for medical use.
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable software for patient case management for use by
healthcare providers for the purpose of viewing and sharing
patient health information, performing healthcare data
analytics, generating patient insights, and managing patient
care. Providing temporary use of non-downloadable cloud-based
software for patient case management for use by healthcare
providers for the purpose of viewing and sharing patient
health information, performing healthcare data analytics,
generating patient insights, and managing patient care.
9.
BODY-MOUNTABLE TEMPERATURE MONITOR ACCOUNTING FOR AMBIENT CONDITIONS
A method of monitoring an internal body temperature of a patient includes detecting a skin temperature of the patient using a temperature sensor in a body-mountable temperature monitor attached to the patient; calculating, using the temperature sensor, a heat flux associated with the body-mountable temperature monitor based on selectively activating a heater in the body-mountable temperature monitor; and determining the internal body temperature of the patient using the skin temperature and the heat flux.
G01K 13/20 - Thermomètres médicaux par contact pour les humains ou les animaux
G01K 1/14 - Supports; Dispositifs de fixation; Dispositions pour le montage de thermomètres en des endroits particuliers
G01K 1/143 - Supports; Dispositifs de fixation; Dispositions pour le montage de thermomètres en des endroits particuliers pour la mesure de la température de surfaces
G01K 1/20 - Compensation des effets des variations de température autres que celles à mesurer, p.ex. variations de la température ambiante
G01K 7/22 - Mesure de la température basée sur l'utilisation d'éléments électriques ou magnétiques directement sensibles à la chaleur utilisant des éléments résistifs l'élément étant une résistance non linéaire, p.ex. une thermistance
10.
Integrating applications in a surgeon console user interface of a robotic surgical system
One example method for improving the efficiency of robotic surgical procedures by integrating applications into the surgeon console user interface is presented. The method includes generating a surgeon console user interface for displaying at a surgeon console associated with a robotic surgical device during a robotic surgical procedure. The surgeon console user interface includes a main region configured for displaying a video signal of the robotic surgical procedure, a left side region for displaying data related to the surgical tools controlled by a left hand controller; and a right side region for displaying data related to the surgical tools controlled by a right hand controller. The method further includes displaying the graphical user interface on a display device of the surgeon console and integrating applications into the surgeon console user interface in response to determining that the surgeon console switches to an application mode.
G06F 3/0484 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p.ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs
11.
Health status change detection using anomaly detection in latent spaces
Individual-specific changes in health conditions are detected using a latent space mapping generated from baseline physiological data collected in a longitudinal study of the individual. Historical baseline data in an n-dimensional input space is modeled into a k-dimensional latent space, where k
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G06N 3/088 - Apprentissage non supervisé, p.ex. apprentissage compétitif
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients
G16H 50/80 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la détection, le suivi ou la modélisation d’épidémies ou des pandémies, p.ex. de la grippe
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Computer hardware for scientific research, namely, for
collecting, processing, and taking anatomical and tissue
images in connection with scientific and medical research;
computer hardware for capturing, transmitting and displaying
images of the eye. Retinal imaging camera for medical screening and medical
diagnostic purposes. Image-based screening services in the field of diabetic
retinopathy for medical research purposes; image-based
screening, grading and characterization services in the
field of pathology for medical research purposes; providing
diagnostic research services not for medical purposes in the
field of diabetic retinopathy research; providing
image-based diagnostic research services not for medical
purposes in the field of diabetic retinopathy research;
genetic screening for research purposes; immunophenotyping
services for research purposes; drug screening for research
services; pharmaceutical drug development services. Medical diagnostic testing, namely, image-based screening
and diagnostic services in the field of diabetic
retinopathy; medical diagnostic testing, namely, image-based
screening, diagnostic, grading and characterization services
in the field of pathology.
13.
RETINAL CAMERAS HAVING VARIABLY SIZED OPTICAL STOPS THAT ENABLE SELF-ALIGNMENT
Introduced here are retinal cameras having optical stops whose size can be adjusted to enable self-alignment by naturally guiding an eye toward a specified location. Generally, a retinal camera will constrict the bounds of an optical stop until the optical stop is aligned with the eye. In some embodiments, the optical stop is mechanically resized as a subject shifts their eye. In some embodiments, the optical stop is digitally created using a pixelated liquid crystal display (LCD) layer having multiple pixels that are individually controllably. In some embodiments, multiple non-pixelated LCD layers are connected to one another to form a variable transmission stack. In such embodiments, the size of the optical stop can be varied by changing which LCD layer(s) are active at a given point in time.
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
14.
Integrating applications in a surgeon console user interface of a robotic surgical system
One example method for improving the efficiency of robotic surgical procedures by integrating applications into the surgeon console user interface is presented. The method includes generating and displaying a first graphical user interface at a surgeon console associated with a robotic surgical device during a robotic surgical procedure, and detecting a combination of user actions through control devices of the surgeon console. The method further includes responsive to detecting the combination of the user actions, causing surgical tools of the robotic surgical device to be locked and generating and displaying a second graphical user interface at the surgeon console which includes user interfaces of applications and is configured to be interactive through the control devices. The method further includes detecting a user action to exit the application mode, causing the surgical tools to be unlocked, and updating and displaying the first graphical user interface at the surgeon console.
G06F 3/14 - Sortie numérique vers un dispositif de visualisation
A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p.ex. des courants à haute fréquence
G05B 19/4155 - Commande numérique (CN), c.à d. machines fonctionnant automatiquement, en particulier machines-outils, p.ex. dans un milieu de fabrication industriel, afin d'effectuer un positionnement, un mouvement ou des actions coordonnées au moyen de données d'u caractérisée par le déroulement du programme, c.à d. le déroulement d'un programme de pièce ou le déroulement d'une fonction machine, p.ex. choix d'un programme
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
H04N 7/18 - Systèmes de télévision en circuit fermé [CCTV], c. à d. systèmes dans lesquels le signal vidéo n'est pas diffusé
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets
15.
Context-aware recommendations in a health management platform user interface
A technique for generating and presenting context-aware recommendations to assist a patient in managing a chronic health condition. A health management platform provides various services that are accessible to a patient via a graphical user interface (GUI). Input data are received from various services and processed to generate contextual data associated with the patient such as a health state of the patient. Using the contextual data, a recommendation to access a particular service is generated and presented to the patient via the GUI. For example, in response to determining a health state of a patient, a recommendation to access a service to improve the health state of the patient can be automatically presented via the GUI to encourage the patient to access the service.
G06F 16/2457 - Traitement des requêtes avec adaptation aux besoins de l’utilisateur
G06F 3/0484 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p.ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs
G06F 9/451 - Dispositions d’exécution pour interfaces utilisateur
G06F 16/9535 - Adaptation de la recherche basée sur les profils des utilisateurs et la personnalisation
G06F 16/9537 - Recherche à dépendance spatiale ou temporelle, p.ex. requêtes spatio-temporelles
G16H 20/30 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies ou des activités physiques, p.ex. la physiothérapie, l’acupression ou les exercices
G16H 20/60 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant le contrôle de l’alimentation, p.ex. les régimes
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
16.
SYSTEMS AND METHODS FOR DYNAMIC RELEASE PLANNING FOR INSECT RELEASE
The disclosure relates to systems and methods for dynamic release planning for insect release. One example method includes receiving information indicating a population of wild insects within a geographic region; determining a number of wild insects per unit area within the geographic region; placing, based on the number of wild insects per unit area, one or more insect release points based on the number of wild insects per unit area, each insect release point indicating a release of a predefined quantity of insects; and generating an insect release route through the geographic region, the insect release route passing through each insect release point.
A01M 1/02 - Systèmes fixes pour capturer ou détruire les insectes avec dispositifs pour attirer les insectes
A01K 67/033 - NÉCESSITÉS COURANTES DE LA VIE ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE ÉLEVAGE; AVICULTURE; APICULTURE; PISCICULTURE; PÊCHE; OBTENTION D'ANIMAUX, NON PRÉVUE AILLEURS; NOUVELLES RACES D'ANIMAUX Élevage ou obtention d'animaux, non prévus ailleurs; Nouvelles races d'animaux Élevage ou obtention d'invertébrés; Nouvelles races d'invertébrés
G01C 21/34 - Recherche d'itinéraire; Guidage en matière d'itinéraire
G06Q 10/047 - Optimisation des itinéraires ou des chemins, p. ex. problème du voyageur de commerce
G06Q 50/00 - Systèmes ou procédés spécialement adaptés à un secteur particulier d’activité économique, p.ex. aux services d’utilité publique ou au tourisme
A system includes an acoustic lure and a sensor package disposed within an interior volume of an insect trapping container and a computing device in communication with the acoustic lure and the sensor package configured to instruct the acoustic lure to output an acoustic tone. The computer device is further configured to receive sensor data from the sensor package, the sensor data representative of insects within the interior volume. Responsive to receiving the sensor data, the computing device is configured to instruct an imaging device to capture image data representative of the insects within the interior volume or determine insect count data based on the sensor data. The computing device is configured to then transmit output data to a remote computing system, the output data including at least one of a first portion of the image data or a second portion of the insect count data.
The technology described herein is directed to a fundus camera and, more specifically, to a fundus camera having a display that projects active visual alignment stimuli onto an eye of an examinee via one or more components of an optimal assembly. The active visual alignment stimuli are dynamically adjusted to guide an examinee toward optical alignment for fundus imaging.
A61B 3/15 - Dispositions spécialement adaptées à la photographie de l'œil avec des moyens d'alignement, d'espacement ou de suppression des réflexions parasites
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/032 - Dispositifs pour présenter des symboles ou des caractères d'épreuve, p.ex. projecteurs de mires
A61B 3/11 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la distance interpupillaire ou le diamètre de la pupille
A61B 3/113 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
Systems and methods for using a prediction model jointly with a normalization model to provide prediction results are provided. One example method includes receiving an input image of a tissue sample of a patient and generating a normalized image by applying a normalization model on the input image. The normalization model is configured to generate normalized data using input data for a prediction model, and the prediction model is configured to generate prediction results using normalized data generated by the normalization model. The normalization model and the prediction model are jointly trained. The method further includes generating a prediction of disease severity for the patient by applying the prediction model on the normalized image.
Provided herein are compositions and methods for assaying target proteins on extracellular vesicles in plasma. In some methods, the responsiveness of a subject to immunotherapy is determined.
G01N 33/574 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour le cancer
G01N 33/542 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet avec formation d'un complexe immunologique en phase liquide avec inhibition stérique ou modification du signal, p.ex. extinction de fluorescence
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable software for data analytics in the fields of
drug discovery, personalized medicine and patient care
pathways. Providing data analytics and machine learning services in
the fields of drug development, personalized medicine and
patient care pathways (term considered too vague by the
International Bureau - Rule 13 (2) (b) of the Regulations);
providing non-downloadable software for data analytics in
the fields of drug discovery, personalized medicine and
patient care pathways.
22.
GENERATING IMAGES OF VIRTUALLY STAINED BIOLOGICAL SAMPLES
One example method for generating images of virtually stained biological samples includes receiving a first image pair comprising a first image of a biological sample and a second image of the biological sample, the first image captured using a first imaging technique and the biological sample being unstained, the second image captured using a second imaging technique different from the first imaging technique and the biological sample being stained; receiving a proposed alignment of the first image and the second image; generating alignment quality information corresponding to the first image pair, the alignment quality information indicating an alignment confidence of the first and second images; training a machine learning ("ML") model, using the first image pair and the alignment quality information, to generate an output image of the biological sample having a virtual stain according to the second imaging technique from the first image; receiving, by the ML model, a first input image of a first biological sample captured using the first imaging technique, the first biological sample being unstained; and generating, by the ML model, a first output image according to the second imaging technique, the first output image comprising a virtually stained image of the first biological sample.
G06T 7/32 - Détermination des paramètres de transformation pour l'alignement des images, c. à d. recalage des images utilisant des procédés basés sur la corrélation
G06T 7/35 - Détermination des paramètres de transformation pour l'alignement des images, c. à d. recalage des images utilisant des procédés statistiques
23.
RETINAL IMAGING SYSTEM AND RETINAL IMAGING ADAPTOR AND RELATED METHODS OF USE
A retinal imaging system and a retinal imaging adaptor and related methods of use are described. In an embodiment, the retinal imaging system comprises a monocular image sensor adapted to acquire a retinal image of an eye; and a binocular eye piece configured to slide relative to the monocular image sensor and shaped to couple to a face of a user. In an embodiment, the monocular image sensor is positioned to acquire a first retinal image of a first eye of the user in a first position of the binocular eye piece and to acquire a second retinal image of a second eye of the user in a second position of the binocular eye piece. In an embodiment, the retinal imaging system includes a sliding bracket coupled to a housing of the retinal imaging system and slidably coupled to the binocular eye piece.
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
24.
Use of intermediate frames to capture and adjust low frame-rate, single-light source images
Systems, methods, and non-transitory, machine-readable storage media for imaging a scene are described. In an embodiment, the method includes repeatedly illuminating a scene with illumination light from a plurality of light sources; generating video feed of the scene based on the scene illuminated by the illumination light; illuminating the scene with only individual light sources of the plurality of light sources between illuminating the scene with the plurality of light sources; generating a composite image of the scene based on the scene illuminated by only the individual light sources; and adjusting the composite image based upon input received from the user interface.
Introduced here are retinal cameras having optical stops whose size and/or position can be modified to increase the size of the space in which an eye can move while being imaged. In some embodiments, an optical stop is mechanically moved to recover retinal image quality as the subject shifts their eye. In some embodiments, an optical stop is digitally created using a pixelated liquid crystal display (LCD) layer having multiple pixels that are individually controllably. In some embodiments, multiple non-pixelated LCD layers are connected to one another to form a variable transmission stack, and each LCD layer within the variable transmission stack may be offset from the other LCD layers. In such embodiments, the optical stop can be moved by changing which LCD layer is active at a given point in time.
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/113 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
G02F 1/1334 - Dispositions relatives à la structure basées sur des cristaux liquides dispersés dans un polymère, p.ex. cristaux liquides micro-encapsulés
To better understand the impact of glycemic events, some entities have begun examining the relationship between the blood glucose level and another physiological parameter. However, this relationship can be difficult to understand. Introduced here are computer programs and associated computer-implemented techniques for discovering glycemic events in a series of data values representative of blood glucose measurements and then altering the measurement schedule of a sensor capable of generating measurements in a dimension other than blood glucose based on the glycemic events. By altering the measurement schedule of the sensor, a diabetes management platform can better understand how, if at all, dimensions other than blood glucose are related to the glycemic health state of a subject whose blood glucose level is being monitored.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p.ex. leur création ou leur transmission
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
27.
Bi-layered neural interface with nerve-facing drug eluting structure
A implantable neural electrode assembly is described. The implantable neural electrode assembly includes a plurality of open-ended rings alternatingly connected to a spine. An inner layer of the open-ended rings is formed from a drug-loaded material (e.g., silicone that has been loaded with a steroid) and an outer layer is formed from a drug-free material. One or more electrode assemblies are connected to the inner layer and oriented towards a center of a cylinder defined by the plurality of open-ended rings.
A61K 31/573 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrène; Leurs dérivés, p.ex. stéroïdes substitués en position 17 bêta par une chaîne à deux atomes de carbone, p.ex. prégnane ou progestérone substitués en position 21, p.ex. cortisone, dexaméthasone, prednisone ou aldostérone
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A portable photo studio system includes a portable photo studio and an electronic device such as a camera-enabled smartphone. A computer system is provided that interacts with the electronic device. The computer system requests an image capture system. In response, the electronic device captures image data and shares it with the computer system. The computer system then analyzes the image data to identify areas of interest.
H04N 7/18 - Systèmes de télévision en circuit fermé [CCTV], c. à d. systèmes dans lesquels le signal vidéo n'est pas diffusé
G06F 16/54 - Navigation; Visualisation à cet effet
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p.ex. DICOM, HL7 ou PACS
H04N 23/54 - Montage de tubes analyseurs, de capteurs d'images électroniques, de bobines de déviation ou de focalisation
H04N 23/56 - Caméras ou modules de caméras comprenant des capteurs d'images électroniques; Leur commande munis de moyens d'éclairage
Systems and methods for authenticating surgical tools for use in a surgical operation by a robotic surgical system are described herein. The authentication systems and methods include status lists for surgical tools associated with surgical systems. The status lists indicate an allowed or disallowed status of each surgical tool. The status list is stored on a cloud-computing system and shared with various surgical systems at different geographic locations. Prior to performing a surgical operation or at other times, the surgical systems decrypt tool data received from a surgical tool to access identifying information and access a tool status from the status list based on the tool data. The surgical systems then proceed based on the status of the surgical tool in the status list.
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
The technology described herein is related to a two-phase deployment-initiated wakeup mechanism for a body-mountable electronic device. During a first phase of the two-phase wakeup mechanism, a motion sensor detects an acceleration event indicative of deployment of the device onto the body of the user. During a second phase of the two-phase mechanism, control circuitry can be adapted to be enabled by the acceleration event. Once enabled, the control circuitry can verify that the device has been launched onto the body of a user via a deployment applicator in which the device is retained until deployment. Once verified, the control circuitry can wake up the body-mountable electronic device by transitioning the device from a sleep state to a functional (or operational) state.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
(1) Wearable devices for the detection, monitoring, and management of health and physiological data, not for medical use, namely, wearable activity and biometric data trackers, and wearable computers in the nature of smartwatches not for medical use.
(2) Wearable devices for the detection, monitoring, and management of health and physiological data, namely, wearable activity and biometric data trackers, wearable computers in the nature of smartwatches, and medical apparatus and instruments for monitoring vital signs, blood properties and respiratory properties and events; all the foregoing for medical use.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
(1) Computer hardware for scientific research, namely, for collecting, processing, and taking anatomical and tissue images in connection with scientific and medical research; computer hardware for capturing, transmitting and displaying images of the eye.
(2) Retinal imaging camera for medical screening and medical diagnostic purposes. (1) Image-based screening services in the field of diabetic retinopathy for medical research purposes; image-based screening, grading and characterization services in the field of pathology for medical research purposes; providing diagnostic research services not for medical purposes in the field of diabetic retinopathy research; providing image-based diagnostic research services not for medical purposes in the field of diabetic retinopathy research; genetic screening for research purposes; immunophenotyping services for research purposes; drug screening for research services; pharmaceutical drug development services.
(2) Medical diagnostic testing, namely, image-based screening and diagnostic services in the field of diabetic retinopathy; medical diagnostic testing, namely, image-based screening, diagnostic, grading and characterization services in the field of pathology.
33.
Distinguishing artifacts from pathological features in digital images
Introduced here are approaches to assessing whether digital features (or simply “features”) detected in digital images by detection models are representative of artifacts that can obscure actual pathologies. A diagnostic platform may characterize each digital feature detected in a digital image based on its likelihood of being an artifact. For instance, a digital feature could be characterized as being representative of an artifact caused by improper illumination, an artifact caused by a physical element that is adhered to the lens through which light is collected by an imaging device, or a pathological feature indicative of a disease.
G06T 7/80 - Analyse des images capturées pour déterminer les paramètres de caméra intrinsèques ou extrinsèques, c. à d. étalonnage de caméra
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
Systems are provided for detecting the flow of blood in vasculature by illuminating the blood with a source of coherent illumination and detecting one or more time-varying properties of a light speckle pattern that results from the scattering of the coherent illumination by tissue and blood. The movement of blood cells and other light-scattering elements in the blood causes transient, short-duration changes in the speckle pattern. High-frequency sampling or other high-bandwidth processing of a detected intensity at one or more points in the speckle pattern could be used to determine the flow of blood in the vasculature. Such flow-measuring systems are also presented as wearable devices that can be operated to detect the flow in vasculature of a wearer. Systems and methods provided herein can additionally be applied to measure flow in other scattering fluid media, for example in a scattering industrial, medical, pharmaceutical, or environmental fluid.
The present disclosure relates to activity monitoring systems and methods for gating whether or not steps should be counted in an observation window based on whether a decision tree concludes there are consecutive step activities (versus no activity or other activities) in the observation window. Particularly, certain aspects are directed to a method that includes obtaining acceleration data for an observation window of an accelerometer, inputting two or more characteristics of the acceleration data into a decision tree to determine activity occurring within the observation window, assigning a first class to the observation window when the determined activity is associated with consecutive steps, assigning a second class to the observation window when the determined activity is not associated with consecutive steps, and when the first class is assigned to the observation window, determining a step count for the observation window using frequency analysis.
The present disclosure relates to implantable neuromodulation devices, and in particular to a wireless power coil for a neuromodulation device that is to be implanted in a minimally invasive manner, for example, through a trocar or cannula. Particularly, aspects of the present disclosure are directed to a medical device that includes a lossy housing surrounding a power supply, and a receiving coil configured to exchange power wirelessly via a wireless power transfer signal and deliver the power to the power supply. The receiving coil is spaced a predetermined distance from the lossy housing. The medical device further includes a gap provided between the lossy housing and the receiving coil on a vertical plane, and a spacer that fills in at least a portion of the gap to maintain the lossy housing a predetermined distance from the receiving coil.
H02J 50/90 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la détection ou l'optimisation de la position, p.ex. de l'alignement
H02J 50/70 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la réduction des champs de fuite électriques, magnétiques ou électromagnétiques
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
37.
Variable content customization for coaching service
A computer-implemented method of a coaching service with variable content objects. The method can include invoking a content flow including an ordered sequence of content objects. The content flow is arranged in accordance with a coaching protocol for a user of a user device. The user accesses a coaching service through the user device. The method further includes causing the user device to present a first content object. The first content object is prearranged in the ordered sequence of content objects based on information associated with the user. The method further includes dynamically selecting a second content object to replace a next content object of the ordered sequence of content objects and advancing the content flow to the second content object in lieu of the next content object and in accordance with the coaching protocol.
G09B 19/00 - Enseignement non couvert par d'autres groupes principaux de la présente sous-classe
G09B 5/02 - Matériel à but éducatif à commande électrique avec présentation visuelle du sujet à étudier, p.ex. en utilisant une bande filmée
G09B 5/04 - Matériel à but éducatif à commande électrique avec présentation sonore du sujet à étudier
G09B 5/06 - Matériel à but éducatif à commande électrique avec présentation à la fois visuelle et sonore du sujet à étudier
G16H 20/60 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant le contrôle de l’alimentation, p.ex. les régimes
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
H04L 65/60 - Diffusion en flux de paquets multimédias
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G16H 20/00 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients
G06F 16/438 - Présentation des résultats des requêtes
H04N 21/466 - Procédé d'apprentissage pour la gestion intelligente, p.ex. apprentissage des préférences d'utilisateurs pour recommander des films
H04N 21/482 - Interface pour utilisateurs finaux pour la sélection de programmes
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients
G16H 20/70 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mentales, p.ex. la thérapie psychologique ou le training autogène
38.
Artificial neural network model for prediction of mass spectrometry data of peptides or proteins
The present invention relates to proteomics, and techniques for predicting of mass spectrometry data of chains of amino acids, such as peptides, proteins, or combinations thereof. Particularly, aspects of the present invention are directed to a computer implemented method that includes obtaining a digital representation of a peptide sequence, the digital representation including a plurality of container elements, each container element of the plurality of container elements representing an amino acid residue; encoding, using a bidirectional recurrent neural network of long short term memory cells, each container element as an encoded vector; and decoding, using a fully-connected network, each of the encoded vectors into a theoretical output spectrum. The theoretical output spectra are represented as a one-dimensional data set or a multi-dimensional data set including intensity values for each fragment ion including one or more of the amino acid residues in the theoretical output spectra.
G16B 30/00 - TIC spécialement adaptées à l’analyse de séquences impliquant des nucléotides ou des aminoacides
G06N 3/049 - Réseaux neuronaux temporels, p.ex. éléments à retard, neurones oscillants ou entrées impulsionnelles
G16B 40/00 - TIC spécialement adaptées aux biostatistiques; TIC spécialement adaptées à l’apprentissage automatique ou à l’exploration de données liées à la bio-informatique, p.ex. extraction de connaissances ou détection de motifs
G16B 40/10 - Traitement du signal, p.ex. de spectrométrie de masse ou de réaction en chaîne par polymérase
G06F 18/214 - Génération de motifs d'entraînement; Procédés de Bootstrapping, p.ex. ”bagging” ou ”boosting”
G16B 20/00 - TIC spécialement adaptées à la génomique ou protéomique fonctionnelle, p. ex. corrélations génotype-phénotype
G16B 45/00 - TIC spécialement adaptées à la visualisation de données liées à la bio-informatique, p. ex. affichage de cartes ou de réseaux
G16B 50/00 - TIC pour la programmation d’outils ou de systèmes de bases de données spécialement adaptées à la bio-informatique
A machine learning predictor model is trained to generate a prediction of the appearance of a tissue sample stained with a special stain such as an IHC stain from an input image that is either unstained or stained with H&E. Training data takes the form of thousands of pairs of precisely aligned images, one of which is an image of a tissue specimen stained with H&E or unstained, and the other of which is an image of the tissue specimen stained with the special stain. The model can be trained to predict special stain images for a multitude of different tissue types and special stain types, in use, an input image, e.g., an H&E image of a given tissue specimen at a particular magnification level is provided to the model and the model generates a prediction of the appearance of the tissue specimen as if it were stained with the special stain. The predicted image is provided to a user and displayed, e.g., on a pathology workstation.
G06F 18/214 - Génération de motifs d'entraînement; Procédés de Bootstrapping, p.ex. ”bagging” ou ”boosting”
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
Described herein are systems and methods of collecting, processing, and analyzing breath exhaled from a subject. Specifically, described herein are systems and methods for minimizing the amount of breath needed for analysis. Further disclosed herein are systems and methods to analyze compounds contained in a subject's breath that are indicative of certain ailments and/or present in a low concentration in the subject's breath. The systems can include a reaction chamber, a breath inlet, a reactant inlet, a fluid atomizer, and a receiving substrate for analyzing the process subject's breath. The methods can include reacting a subject's breath with a reactant to analyze the contents of the subject's breath.
A method for comparing videos of a surgical procedure is disclosed. The method comprising selecting a plurality of videos from a surgical video database. Each of the plurality of videos including video data of a first surgical procedure comprising a plurality of surgical steps. The method further including identifying a first surgical step included in the plurality of surgical steps within a first video segment in each of the plurality of videos. The method also including warping the first video segment to standardize a dimension of the first video segment in each of the plurality of videos.
Systems and methods for transporting live insects in a secure and environmentally controlled manner. The systems include containers and packaging for transporting the live insects at a controlled temperature and pressure.
A01K 67/033 - NÉCESSITÉS COURANTES DE LA VIE ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE ÉLEVAGE; AVICULTURE; APICULTURE; PISCICULTURE; PÊCHE; OBTENTION D'ANIMAUX, NON PRÉVUE AILLEURS; NOUVELLES RACES D'ANIMAUX Élevage ou obtention d'animaux, non prévus ailleurs; Nouvelles races d'animaux Élevage ou obtention d'invertébrés; Nouvelles races d'invertébrés
B65D 81/38 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu avec isolation thermique
B65D 85/50 - Réceptacles, éléments d'emballage ou paquets spécialement adaptés à des objets ou à des matériaux particuliers pour organismes vivants, objets ou matériaux sensibles aux changements d'ambiance ou de conditions atmosphériques, p.ex. pour animaux terrestres, oiseaux, poissons, plantes aquatiques, plantes non aquatiques, oignons de fleurs, fleurs coupées ou feui
B65B 31/00 - Emballage d'objets ou de matériaux dans des conditions atmosphériques ou gazeuses particulières; Addition de propergols à des réceptacles pour aérosols
B65D 81/20 - Réceptacles, éléments d'emballage ou paquets pour contenus présentant des problèmes particuliers de stockage ou de transport ou adaptés pour servir à d'autres fins que l'emballage après avoir été vidés de leur contenu fournissant une ambiance spécifique pour le contenu, p.ex. température supérieure ou inférieure à la température ambiante sous vide ou pression superatmosphérique ou en atmosphère spéciale, p.ex. sous gaz inerte
A system for imaging a retina of an eye includes a first lens for positioning proximate to the eye; a light source positioned to illuminate the eye when the system is aligned with the eye; an image sensor adapted to capture a retinal image of the retina through the first lens; an aperture disposed along an optical path extending from the image sensor and passing through the first lens; and a processing apparatus communicatively coupled to the image sensor and the light source, wherein the processing apparatus includes logic that when executed by the processing apparatus causes the system to perform operations including: illuminating the eye with the light source and capturing the retinal image with the image sensor.
G06T 5/50 - Amélioration ou restauration d'image en utilisant plusieurs images, p.ex. moyenne, soustraction
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/11 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour mesurer la distance interpupillaire ou le diamètre de la pupille
44.
COMBINED VISION AND LANGUAGE LEARNING MODELS FOR AUTOMATED MEDICAL REPORTS GENERATION
A method of generating a medical report is presented herein. In some embodiments, the method includes receiving a medical image and at least one natural language medical question, extracting at least one image feature from the image; extracting at least one text feature from the question; and fusing the at least one image feature with the at least one text feature to form a combined feature. Some embodiments further include encoding, by an encoder, the combined feature to form a transformed combined feature; computing a set of prior context features based on a similarity between the transformed combined feature and each of a set of transformed text features derived from a set of training natural language answers; and generating, by a decoder, a first natural language answer conditioned on the transformed combined feature and the set of prior context features.
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
G06F 40/40 - Traitement ou traduction du langage naturel
G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”
G06V 10/80 - Fusion, c. à d. combinaison des données de diverses sources au niveau du capteur, du prétraitement, de l’extraction des caractéristiques ou de la classification
45.
PATHOLOGY AND/OR EYE-SIDED DEPENDENT ILLUMINATION FOR RETINAL IMAGING
A retinal imaging system includes an eyepiece lens assembly, an image sensor adapted to acquire a retinal image of an eye through the eyepiece lens assembly, and a controller communicatively coupled to the image sensor. The controller including logic that when executed causes the retinal imaging system to perform operations including: obtaining an indication of a pathology of interest (POI) related to the eye or an eye sidedness, selecting an eyebox location for an eyebox of the retinal imaging system based at least in part on the POI or an eye sidedness, and acquiring the retinal image of the eye when the eye is determined to be positioned within the eyebox. The eyebox corresponds to a bound region in space defined relative to the eyepiece lens assembly.
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A system and method of identifying an adverse event using a video of a surgery and a two-stage surgical phase recognition module. The method includes receiving, by the module, a video of the surgery, where the video comprises a sequence of video frames. The module comprises a first stage that includes a neural network and a second stage that includes a multi-stage temporal convolution network. The method includes extracting, using the first stage, visual information content of a single frame based on the single frame; identifying, using the second stage, surgical phases captured in the frames of the video based on the visual information content from the first stage; and identifying, using the identified surgical phases, an adverse event during the surgery. An adverse event includes the omission of a surgical phase and an injury to the patient. The identification can occur in real-time or near-real-time.
Introduced here is a method, a system, a device, etc. for displaying health-related data (e.g., blood glucose measurements) relevant to user's selection. The method, the system, the device, etc. can be based on: receiving healthcare-related data from data streams associated with a profile of a patient; identifying, based on a least a subset of the data streams, a time window corresponding to a contextual event indicative of a patient activity that has a potential of affecting metabolism of the patient; determining a graphical representation of the contextual event; generating a graph of blood glucose level over time for display; detecting a user indication of a user interest in a time point along the graph of the blood glucose level; and highlighting the graphical representation of the contextual event in response to the time point falling within the identified time window.
G06F 3/04817 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] fondées sur des propriétés spécifiques de l’objet d’interaction affiché ou sur un environnement basé sur les métaphores, p.ex. interaction avec des éléments du bureau telles les fenêtres ou les icônes, ou avec l’aide d’un curseur changeant de comport utilisant des icônes
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G06F 9/451 - Dispositions d’exécution pour interfaces utilisateur
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
G16H 20/60 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant le contrôle de l’alimentation, p.ex. les régimes
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
An imaging system includes an endoscope tube, an illumination system, first and second image sensors, and a controller. The illumination system is coupled to the endoscope tube and configured to emit first illumination light having a first wavelength profile and excitation light having an excitation wavelength profile outside of the first wavelength profile. The first image sensor is aligned with a first filter configured to pass first image light, received in response to the first illumination light, to the first image sensor and to block the excitation light. The second image sensor is aligned with a second filter configured to pass fluorescence light, emitted in response to the excitation light, to the second image sensor. The controller includes logic to simultaneously illuminate a scene with the first illumination light and the excitation light and capture first image data and fluorescence image data with the first and second image sensors.
A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement
A61B 1/04 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision
A61B 1/05 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments combinés avec des dispositifs photographiques ou de télévision caractérisés par le fait que le capteur d'images, p.ex. l'appareil photographique, est placé dans la partie de l'extrémité distale
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
Insect storage and dispensing system are described. An example system may include a dispensing container including at least one wall defining an interior volume for retaining a plurality of adult insects. The system may also include a piston that extends through a first opening of the dispensing container so as to expose a top face of the piston to the interior volume. Longitudinal movement of the piston toward a second opening of the dispensing container may dispense a portion of the plurality of insects from the dispensing container when the plurality of insects is retained in the dispensing container.
An insect dispensing system is described. The insect dispensing system includes a plate diverting structure supported by a frame. A first plate of the structure includes a set of channels and a second plate of the structure includes a set of apertures. The plates are aligned such that one end of each channel is aligned with one of the apertures. A population of insect pupae suspended in a liquid is dispensed into the set of channels via an inlet. As the liquid flows through the system, it is distributed among the set of channels, ultimately exiting via the apertures into a set of catch basins.
An insect separating apparatus may include a sensor positioned to detect one or more insects when present within a test chamber. For example, the sensor may emit signals into the test chamber and receive reflected signals indicative of Doppler shifts caused by movement of the one or more insects. Based on information from the sensor, a computing device may determine a characteristic of the one or more insects in the chamber, such as a wing beat frequency, sex, or other characteristic. The computing device may instruct different responses based on the characteristic determined, such as activating an air mover to divert detected mosquitos out of the test chamber in response to the determined characteristics matching those of female mosquitos, or deactivating or maintaining the air mover in an inactive condition in response to the determined characteristics matching those of male mosquitos, for example, to allow passage through the chamber into a collection receptacle.
Systems and methods for continuous insects sensing are described. One example method includes receiving a flow at a singulator, the flow comprising one or more insects; singulating the insects into a single-file flow of insects; sensing, using a sensor, insects within the single-file flow of insects; and incrementing a counter based on each sensed insects in the single-file flow of insects. One example system includes a channel defining a flow path for a flow of insects; a singulator positioned within the flow path and arranged to receive the flow of insects within the channel, the singulator configured to singulate the insects into a single-file flow of insects; a sensor positioned and arranged to sense insects in the single-file flow; and a processor in communication with the sensor and a non-transitory computer-readable medium, the processor configured to execute processor-executable instructions stored in the non-transitory computer-readable medium to receive sensor signals from the sensor; and count a number of insects based on the received sensor signals.
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Downloadable software for patient case management for use by healthcare providers for the purpose of viewing and sharing patient health information, performing healthcare data analytics, generating patient insights, and managing patient care. (1) Providing temporary use of non-downloadable cloud-based software for patient case management for use by healthcare providers for the purpose of viewing and sharing patient health information, performing healthcare data analytics, generating patient insights, and managing patient care.
54.
Transforming multispectral images to enhanced resolution images enabled by machine learning
Systems and methods for predicting images with enhanced spatial resolution using a neural network are provided herein. According to an aspect of the invention, a method includes accessing an input image of a biological sample, wherein the input image includes a first spatial resolution and a plurality of spectral images, and wherein each spectral image of the plurality of spectral images includes data from a different wavelength band at a different spectral channel; applying a trained artificial neural network to the input image; generating an output image at a second spatial resolution, wherein the second spatial resolution is higher than the first spatial resolution, and wherein the output image includes a fewer number of spectral channels than the plurality of spectral images included in the input image; and outputting the output image.
In some embodiments, readily understandable information displays are provided to help an operator guide an eye of a subject into an eyebox of a retinal imaging system. In some embodiments, a three-dimensional position of the eye with respect to the retinal imaging system is determined, and an interface that includes a three-dimensional representation of the position of the eye with respect to the eyebox is generated. In some embodiments, the gaze direction may also be determined and presented in the interface, so that the operator can also prompt the subject to correct issues with incorrect gaze direction.
A61B 3/10 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/02 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure subjective, c. à d. appareils de d’examen nécessitant la participation active du patient
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/113 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
A61B 3/08 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure subjective, c. à d. appareils de d’examen nécessitant la participation active du patient pour examen de vision binoculaire ou stéréoscopique, p.ex. pour le contrôle du strabisme
56.
Transmitting sensitive information securely over unsecured networks without authentication
Methods and apparatus for encrypting and decrypting data for wearable devices that are not based on authentication techniques, such as login/password or handshaking, are provided. A computing device receives a message. The message includes encrypted data and a cryptographic reference. The encrypted data includes physiological data of a wearer of the wearable device. The cryptographic reference includes a reference to a first cryptographic technique. The computing device determines the first cryptographic technique based on the reference to the first cryptographic technique. The computing device determines a cryptographic key. The computing device decrypts the encrypted data using the first cryptographic technique and the cryptographic key to obtain decrypted data. The computing device stores the decrypted data.
Introduced here are approaches to assessing digital images generated during image capture sessions using a machine learning model so as to stratify patients for examination. By applying the machine learning model to the digital images, the patients that are most in need of further examination can be identified to graders. For example, outputs produced by the diagnostic model may trigger the generation and transmission of notifications for patients that are deemed to warrant further examination.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/18 - Agencement de plusieurs appareils pour tester ou examiner les yeux
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p.ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
58.
Systems for detecting carious lesions in teeth using short-wave infrared light
Systems, apparatuses, and methods for detecting carious lesions are described herein. In an example, the systems in an optical interrogator including a single-pixel photodetector responsive to short-wave infrared light and operatively coupled to a controller. In an example the optical interrogator includes a light engine for emitting light, a scanning mirror assembly and a single-pixel photodetector. In an example, the methods include causing the light engine to emit light having wavelengths in a range of about 900 nm to about 1,700 nm; selectively directing the light over different portions of a tooth with a scanning mirror assembly to provide scattered light; and correlating scattered light signals generated by the single-pixel photodetector in response to the scattered light with the portion of the tooth.
Endoscopic systems, non-transitory, machine-readable storage media, and methods for correcting brightness non-uniformity are described. In an embodiment, the endoscopic system includes a light source positioned to emit illumination light onto a scene; a photodetector positioned to receive illumination light reflected off of the scene and configured to generate a scene signal based on the received illumination light; a display; and a controller operatively coupled to the light source, the photodetector, and the display. In an embodiment, the controller including logic that, when executed by the controller, causes the endoscopic system to perform operations including: illuminating the scene with the light source; detecting a scene depth; estimating a scene-specific brightness non-uniformity correction based on the detected scene depth and an endoscopic system brightness non-uniformity profile; and displaying an image of the scene with the display based on the scene signal, the detected scene depth, and the endoscopic system brightness non-uniformity correction.
H04N 5/235 - Circuits pour la compensation des variations de la luminance de l'objet
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
H04N 23/74 - Circuits de compensation de la variation de luminosité dans la scène en influençant la luminosité de la scène à l'aide de moyens d'éclairage
H04N 13/239 - Générateurs de signaux d’images utilisant des caméras à images stéréoscopiques utilisant deux capteurs d’images 2D dont la position relative est égale ou en correspondance à l’intervalle oculaire
G06T 7/521 - Récupération de la profondeur ou de la forme à partir de la projection de lumière structurée
A61B 1/06 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments avec dispositifs d'éclairement
60.
Network-connected containers having medication stored therein
Introduced here are containers designed to promote compliance with regimens for administering the medications stored therein. These containers have various features that allow them to be more easily managed by the individuals to whom the medications were prescribed. Some features improve the ease with which containers communicate with individuals. These features may enable information to be more easily input by individuals and/or output for individuals in a comprehensible manner. Other features improve the mechanical or electrical durability of containers. Such features may enable the containers to be used by individuals over the course of several days, weeks, or months without worrying about structural damage or loss of power.
G08B 5/00 - Systèmes de signalisation optique, p.ex. systèmes d'appel de personnes, indication à distance de l'occupation de sièges
A61J 7/04 - Dispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments, p.ex. distributeurs programmés
G16H 20/13 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients delivrés par des distributeurs
G08B 5/36 - Systèmes de signalisation optique, p.ex. systèmes d'appel de personnes, indication à distance de l'occupation de sièges utilisant une transmission électromécanique utilisant des sources de lumière visible
A61J 1/03 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques pour pilules ou comprimés
61.
Devices for tracking opening and closing of containers
Systems and devices for tracking the opening and closing of a container are provided. According to an aspect of the invention, a device includes a body that is configured to be inserted between a container and a cap that is configured to seal the container, a sensor that is configured to measure a state of the cap as being opened or closed, a microprocessor that is configured to receive a signal from the sensor that represents the state of the cap, and a transmitter that is configured to send a message that indicates the state of the cap.
Systems and methods are provided for continuously monitoring a user to determine when cardiovascular events are likely occurring and to responsively provide a prompt to a user to engage in additional physiological assessment of the putative cardiovascular event. Additional assessment can include the user engaging an additional sensor to provide signals that are more accurate, lower noise, or otherwise improved relative to a continuously-monitoring sensor used to initially detect the cardiovascular event. Detection of cardiovascular events includes using a cardiovascular classifier to determine, based on the output of such a continuously-monitoring sensor, whether the event is likely occurring. Such a classifier can be received from a cloud computing service or other remote system based on sensor outputs sent to such a system. Use of such a classifier can facilitate reduced false-positive detection of cardiovascular events based on the continuously-monitoring sensor, and thus reduce extraneous prompts to the user.
A system includes a display, and a database including surgical videos, images of organs in a human body obtained from a medical imaging device, and images of disease in a human body obtained from the medical imaging device. A controller including a processor is coupled to memory, the database, and the display, and the memory stores information that when executed by the processor causes the system to perform operations. For example, the processor may determine first organ information from the images of the organs, and first disease information from the images of the disease. The processor my calculate a similarity score between the first organ information and the first disease information and second disease information and second organ information indexed to the surgical videos. The processor selects one or more of the surgical videos based on the similarity score, and displays the surgical videos on the display.
G06F 16/783 - Recherche de données caractérisée par l’utilisation de métadonnées, p.ex. de métadonnées ne provenant pas du contenu ou de métadonnées générées manuellement utilisant des métadonnées provenant automatiquement du contenu
G06F 16/71 - Indexation; Structures de données à cet effet; Structures de stockage
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p.ex. DICOM, HL7 ou PACS
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p.ex. dispositif en vraie grandeur pour la démonstration pour la médecine
G06V 10/70 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique
Systems and methods for detecting determining a volume of urine in an absorbent article such as a diaper. A diaper loading application obtains a first measurement of ambient light received from a photodetector while a light source is off and a second measurement from the photodetector while the light source is transmitting light on an absorbent article. The application determines a normalized measurement of light reflected from an absorbent article by removing an ambient light signal from the second measurement based on the first measurement. The application determines, from the normalized measurement, a presence of urine in the absorbent article. The application further determines an estimated volume of urine in the absorbent article, wherein the determining is based on an elapsed time since the presence of urine and an activity state of an infant wearing the absorbent article.
A61F 13/42 - Garnitures absorbantes, p.ex. serviettes ou tampons hygiéniques pour application externe ou interne au corps; Moyens pour les maintenir en place ou les fixer; Applicateurs de tampons avec un indicateur ou une alarme d'humidité
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G01P 13/00 - Indication ou enregistrement de l'existence ou de l'absence d'un mouvement; Indication ou enregistrement de la direction d'un mouvement
G01J 1/42 - Photométrie, p.ex. posemètres photographiques en utilisant des détecteurs électriques de radiations
G01N 21/25 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
31 - Produits agricoles; animaux vivants
36 - Services financiers, assurances et affaires immobilières
37 - Services de construction; extraction minière; installation et réparation
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Downloadable computer software for the detection, monitoring, and management of health and physiological data; downloadable computer software for collecting, processing, analyzing, transmitting, validating and displaying health and physiological data; downloadable computer software used to manage clinical trials; computer hardware for capturing, transmitting and displaying anatomical imaging data; downloadable computer software for clinical trial data collection, storage and analysis; downloadable software for patient case management for use by healthcare providers for the purpose of viewing and sharing patient health information, performing healthcare data analytics, generating patient insights, and managing patient care; computer hardware for scientific research, namely, for collecting, processing, and taking anatomical and tissue images in connection with scientific and medical research; computer hardware for capturing, transmitting and displaying images of the eye; wearable devices for the detection, monitoring, and management of health and physiological data, not for medical use, namely, wearable activity and biometric data trackers, and wearable computers in the nature of smartwatches not for medical use Medical instruments and apparatus, namely, medical apparatus for detection, monitoring, and management of health and physiological data, namely, wearable activity and biometric data trackers, wearable computers in the nature of smartwatches, and medical apparatus and instruments for monitoring vital signs, blood properties and respiratory properties and events; all the foregoing for medical use Live insects and insect larvae for insect abatement scientific and medical research Providing health data analytics and care delivery data analytics and insights to insurance providers for purposes of health insurance underwriting Insect control services, namely, reducing population of disease-carrying insects through introduction of sterile males into reproducing populations, other than for agriculture, aquaculture, horticulture and forestry purposes Providing online non-downloadable software for use in collecting, analyzing and providing health data, medical data, wellness data, health risk data, and demographic data; medical research; scientific research services, namely, services for discovering, identifying, analyzing and reporting biomarkers of health and disease; drug screening and development services, namely drug screening for scientific research purposes, and pharmaceutical drug development services; medical and scientific research services in the field of screening, diagnosing, and characterizing disease based on images of anatomy; laboratory research, analysis and testing services in the fields of oncology and virology; providing temporary use of non-downloadable software for collecting, processing, analyzing, transmitting, validating and displaying data in the medical, scientific and pharmaceutical fields; providing temporary use of non-downloadable software for patient case management for use by healthcare providers for the purpose of viewing and sharing patient health information, performing healthcare data analytics, generating patient insights, and managing patient care; platform as a service (PAAS) featuring computer software platforms for researchers to access, share and store clinical research data and biomedical research data, and to run analytical tools; providing data analytics and machine learning services, namely analyzing and organizing clinical, laboratory and genomic data, data mining, scientific research, and machine software and artificial intelligence programing and consulting in the fields of drug development, personalized medicine and patient care pathways; providing temporary use of non-downloadable software for data analytics in the fields of drug discovery, personalized medicine and patient care pathways; providing temporary use of non-downloadable software for conducting clinical trials, including software for recruiting clinical trial participants, managing clinical trials, and collecting, storing and analyzing clinical trial data; providing temporary use of non-downloadable software for image-based medical screening, diagnostic and disease characterization purposes; laboratory services for testing wastewater for pathogens; providing information and analysis of epidemiological information and data pertaining to pathogens in wastewater for scientific research purposes and medical research purpose Medical services in the nature of providing health data analytics and care delivery data analytics and insights to patients, doctors, hospitals, and medical professionals for diagnostic and treatment purposes; laboratory testing for diagnostic and population health purposes in the fields of oncology and virology; medical services, namely, screening, diagnosing or grading the severity of a disease or health condition based on image data
66.
Virtual sidekick in a health management platform user interface
A user interface for a health management platform is described that includes a virtual sidekick configured to assist a patient in managing a chronic health condition. The virtual sidekick may represent an individual (not necessarily the patient) that is facing similar challenges as the patient such as the same chronic health condition as the patient. In some embodiments, the virtual sidekick can be presented in a virtual scene that includes one or more reverse augmented realty elements that are indicative of a physical context of the patient. For example, the virtual scene may depict visual elements indicative of the patient's physical location and/or weather conditions at the patient's physical location. Data used to personalize and dynamically animate the virtual sidekick to assist the patient in managing a chronic health condition can come from multiple different sources.
G06F 3/048 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI]
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
G06F 3/14 - Sortie numérique vers un dispositif de visualisation
G06F 9/451 - Dispositions d’exécution pour interfaces utilisateur
67.
SYSTEMS AND METHODS FOR USING IMAGE PROCESSING TO GENERATE INFERENCES of BIOMARKER FOR IMMUNOTHERAPY
Methods and systems are disclosed for image process biological samples to infer biomarker values. An image of a biological sample can be accessed. The image can be segmented into a set of patches. Edge detection performed on each patch can be used to identify one or more biological features represented by the patch. An indication of the one or more features of each patch may be used to generate one or more image level metrics. A value of a biomarker may be inferred using the one or more image level metrics. The value of the biomarker can then be output.
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
G06T 7/155 - Découpage; Détection de bords impliquant des opérateurs morphologiques
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
G06V 10/56 - Extraction de caractéristiques d’images ou de vidéos relative à la couleur
G06V 10/75 - Appariement de motifs d’image ou de vidéo; Mesures de proximité dans les espaces de caractéristiques utilisant l’analyse de contexte; Sélection des dictionnaires
G06V 10/44 - Extraction de caractéristiques locales par analyse des parties du motif, p.ex. par détection d’arêtes, de contours, de boucles, d’angles, de barres ou d’intersections; Analyse de connectivité, p.ex. de composantes connectées
Ionizable lipids and lipid nanoparticles comprising ionizable lipids are provided herein. Also provided are methods for making and using the lipid nanoparticles for delivery to a cell one or more payload agents, including polypeptides, mRNAs such as mRNA encoding Cas9 nuclease, and guide RNAs comprising backbone, sugar or base modifications.
C07C 229/16 - Composés contenant des groupes amino et carboxyle liés au même squelette carboné ayant des groupes amino et carboxyle liés à des atomes de carbone acycliques du même squelette carboné le squelette carboné étant acyclique et saturé ayant un seul groupe amino et un seul groupe carboxyle liés au squelette carboné l'atome d'azote du groupe amino étant lié de plus à des atomes de carbone acycliques ou à des atomes de carbone de cycles autres que des cycles aromatiques à six chaînons à des atomes de carbone de radicaux hydrocarbonés substitués par des groupes amino ou carboxyle, p.ex. acide éthylènediaminetétra-acétique, acides iminodiacétiques
A61K 31/7115 - Acides nucléiques ou oligonucléotides ayant des bases modifiées, c. à d. autres que l'adénine, la guanine, la cytosine, l'uracile ou la thymine
A61K 31/712 - Acides nucléiques ou oligonucléotides ayant des sucres modifiés, c. à d. autres que le ribose ou le 2'-désoxyribose
A61K 31/7125 - Acides nucléiques ou oligonucléotides ayant des liaisons internucléosides modifiées, c. à d. autres que des liaisons 3'-5' phosphodiester
A61K 48/00 - Préparations médicinales contenant du matériel génétique qui est introduit dans des cellules du corps vivant pour traiter des maladies génétiques; Thérapie génique
C07C 219/06 - Composés contenant des groupes amino et hydroxy estérifiés liés au même squelette carboné ayant des groupes hydroxy estérifiés et des groupes amino liés à des atomes de carbone acycliques du même squelette carboné le squelette carboné étant acyclique et saturé les groupes hydroxy étant estérifiés par des acides carboxyliques ayant les groupes carboxyle estérifiants liés à des atomes d'hydrogène ou à des atomes de carbone acycliques d'un squelette carboné acyclique saturé
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Computer hardware for scientific research, namely, for collecting, processing, and taking anatomical and tissue images in connection with scientific and medical research; computer hardware for capturing, transmitting and displaying images of the eye Retinal imaging camera for medical screening and medical diagnostic purposes Image-based screening services in the field of diabetic retinopathy for medical research purposes; image-based screening, grading and characterization services in the field of pathology for medical research purposes; providing diagnostic research services not for medical purposes in the field of diabetic retinopathy research; providing image-based diagnostic research services not for medical purposes in the field of diabetic retinopathy research; genetic screening for research purposes; immunophenotyping services for research purposes; drug screening for research services; pharmaceutical drug development services Medical diagnostic testing, namely, image-based screening and diagnostic services in the field of diabetic retinopathy; Medical diagnostic testing, namely, image-based screening, diagnostic, grading and characterization services in the field of pathology
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Wearable devices for the detection, monitoring, and management of health and physiological data, not for medical use, namely, wearable activity and biometric data trackers, and wearable computers in the nature of smartwatches not for medical use Wearable devices for the detection, monitoring, and management of health and physiological data, namely, wearable activity and biometric data trackers, wearable computers in the nature of smartwatches, and medical apparatus and instruments for monitoring vital signs, blood properties and respiratory properties and events; all the foregoing for medical use
71.
DRUG DELIVERY VEHICLES, METHODS OF PRODUCING DRUG DELIVERY VEHICLES, AND METHODS OF USING DRUG DELIVERY VEHICLES
The present disclosure is related to a method of producing a capsule. The method includes providing a mold, depositing parylene on the mold to form a parylene layer, scoring the parylene layer, and coating the parylene layer with a polymer to produce a capsule.
A device comprises a dispenser assembly comprising a frame having a first surface and a second surface. The frame defines a pathway, an inlet opening in the first surface of the frame and a drain opening in the second surface of the frame. The inlet opening and the drain opening may provide access to the pathway. The device also includes a moveable member having at least one bore oriented perpendicular to the pathway. The moveable member may be translatable within the pathway between a first position and a second position.
A medication dispenser apparatus is described. The apparatus includes a container configured to hold medication, a display interface, and a controller configured to perform, in sequence, a learning operation in which the controller learns a medication dispensing regimen of the container, a validation operation in which the controller validates the learned medication dispensing regimen; and a notification operation in which the controller provides on the display interface a status of use of the container for medication dispensing in relation to the learned medication dispensing regimen.
G16H 20/13 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients delivrés par des distributeurs
A61J 7/04 - Dispositions pour l'indication ou le rappel du moment où l'on doit prendre des médicaments, p.ex. distributeurs programmés
G05B 13/02 - Systèmes de commande adaptatifs, c. à d. systèmes se réglant eux-mêmes automatiquement pour obtenir un rendement optimal suivant un critère prédéterminé électriques
Embodiments of the present disclosure can provide an automated mass rearing system for insect larvae. The automated mass rearing system can facilitate hatching, feeding, monitoring the growth and emergence of insect larvae and pupae. In some embodiments, the automated mass rearing system can include a production unit, a transportation unit, a storage unit, a dispensing unit, and a monitoring unit. In some embodiments, this automated mass rearing system can facilitate mass mosquito growth from egg hatching all the way through to full adults or certain stages in between such as the larvae rearing process (i.e., from larvae to pupae) with little or no human intervention. By automating the rearing and transportation of insect eggs, larvae, and pupae, deaths or developmental issues can be minimized. Various techniques and apparatuses are used in this automation that causes minimal disturbance to the insects during development, and thereby maximizing survival rate and fitness of the insects.
A01K 67/033 - NÉCESSITÉS COURANTES DE LA VIE ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE ÉLEVAGE; AVICULTURE; APICULTURE; PISCICULTURE; PÊCHE; OBTENTION D'ANIMAUX, NON PRÉVUE AILLEURS; NOUVELLES RACES D'ANIMAUX Élevage ou obtention d'animaux, non prévus ailleurs; Nouvelles races d'animaux Élevage ou obtention d'invertébrés; Nouvelles races d'invertébrés
B65G 1/137 - Dispositifs d'emmagasinage mécaniques avec des aménagements ou des moyens de commande automatique pour choisir les objets qui doivent être enlevés
75.
SENSING PHYSIOLOGICAL PARAMETERS THROUGH AN ARTICLE
Various examples are described for detecting heart rate and respiratory rate by using measurements of light applied to skin through an article. For example, a sensor application obtains a set of measurements of light. The application compensates for a contribution of the article based on one or more known optical properties of the article. The sensor application further determines, from the set of measurements of light, a periodic change in amplitude. The sensor application identifies the periodic change in amplitude as a heart rate having an identical periodicity. The sensor application identifies a respiratory rate as equal to the rate of change of the heart rate.
One example method includes receiving an image of a tissue sample stained with a stain; determining, by a first trained machine learning ("ML") model using the image, a first set of abnormal cells in the tissue sample; receiving an autofluorescence image of the unstained tissue sample; determining, by a second trained ML model using the autofluorescence image and the first set of cells, a second set of abnormal cells, the second set of abnormal cells being a subset of the first set of abnormal cells; and identifying the abnormal cells of the second set of abnormal cells.
A dynamic illuminator includes a central aperture, a ring of inner light sources, a plurality of primary illumination arrays, and a plurality of secondary illumination arrays. The ring of inner light sources is arranged around the central aperture. The plurality of primary illumination arrays extends along radial axes from the central aperture outside of the ring of inner light sources, wherein the primary illumination arrays each includes a plurality of primary light sources. The plurality of secondary illumination arrays is disposed along secondary axes extending from the central aperture outside of the ring of inner light sources. The secondary illumination arrays each includes a plurality of secondary light sources. The secondary axes of the secondary illumination arrays are disposed angularly between adjacent ones of the primary illumination arrays.
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
78.
SYSTEMS AND METHODS FOR DIRECTLY PREDICTING CANCER PATIENT SURVIVAL BASED ON HISTOPATHOLOGY IMAGES
One example method includes obtaining one or more histopathology images of a sample from a cancer patient; selecting a plurality of tissue image patches from the one or more histopathology images; determining, by a deep learning system comprising a plurality of trained machine learning (ML) models, a plurality of image features for the plurality of tissue image patch, wherein each tissue image patch is analyzed by one of the trained ML models; determining, by the deep learning system, probabilities of patient survival based on the determined plurality of image features; and generating, by the deep learning system, a prediction of patient survival based on the determined probabilities.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable computer software for clinical trial data collection, storage and analysis. Providing online non-downloadable software for conducting clinical trials, including software for recruiting clinical trial participants, managing clinical trials, and collecting, storing and analyzing clinical trial data; platform as a service (PAAS) featuring computer software platforms for researchers to access, share and store clinical research data and biomedical research data, and to run analytical tools.
80.
DETECTION, IDENTIFICATION, AND VERIFICATION OF PATIENTS INVOLVED IN DIAGNOSTIC SESSIONS
Introduced here are approaches to ensuring that digital images generated during diagnostic sessions are properly associated with the appropriate patients. By implementing these approaches, a diagnostic platform can minimize the time needed to manually input information prior to a diagnostic session and improve the accuracy of this information.
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p.ex. DICOM, HL7 ou PACS
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
Devices, systems, and methods for transporting or transferring insect pupae in an aqueous solution are described. The system includes a tank containing a solution with insect pupae, a transfer chamber having an outlet at a bottom portion of the chamber, a solution inlet, an evacuation channel, and a depth measurement system. A tube fluidly connects to tank and the transfer chamber. An evacuation device connected to the evacuation channel removes air from the transfer chamber and generates a vacuum therein to draw the solution through the tube into the transfer chamber.
The present disclosure relates to thin-film lead assemblies and neural interfaces with stent-assisted deployment, and methods of microfabricating thin-film lead assemblies and neural interfaces. Particularly, aspects of the present disclosure are directed to a medical device having a thin-film neural interface, a stent, and a cable. The thin-film neural interface includes a first supporting structure, electrodes formed on the first supporting structure, and an encapsulation material encasing a portion of the first supporting structure. The cable includes a second supporting structure, conducive traces formed on the second supporting structure and electrically connected with the electrodes, and the encapsulation material encasing at least a portion of the second supporting structure. The stent is at least partially embedded in the encapsulation material encasing the portion of the first supporting structure, and the thin-film neural interface is helically wrapped around at least a portion of the stent.
A61F 2/90 - Stents ayant une forme caractérisée par des éléments filiformes; Stents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles
A61F 2/95 - Instruments spécialement adaptés pour insérer ou retirer les stents ou les endoprothèses déployables couvertes
83.
SURGICAL WORKFLOW AND ACTIVITY DETECTION BASED ON SURGICAL VIDEOS
One example method for detecting phases of a surgical procedure via video processing includes accessing a video of the surgical procedure and dividing the video into one or more blocks, each of the blocks containing one or more video frames. For each of the blocks, the method includes applying a prediction model on the video frames of the respective block to obtain a phase prediction for each of the video frames. The prediction model is configured to predict, for an input video frame, one of the plurality of phases of the surgical procedure. The method further includes generating an aggregated phase prediction for the respective block by aggregating the phase predictions of the video frames, and modifying the video of the surgical procedure to include an indication of a predicted phase of the respective block based on the aggregated phase prediction.
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
G06V 20/40 - RECONNAISSANCE OU COMPRÉHENSION D’IMAGES OU DE VIDÉOS Éléments spécifiques à la scène dans le contenu vidéo
G06V 10/774 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant l’intégration et la réduction de données, p.ex. analyse en composantes principales [PCA] ou analyse en composantes indépendantes [ ICA] ou cartes auto-organisatrices [SOM]; Séparation aveugle de source méthodes de Bootstrap, p.ex. "bagging” ou “boosting”
84.
Device, system, and formulation for oral delivery of functionalized particles
A device includes a capsule sized to pass through a lumen of a gastrointestinal tract; an enteric coating surround at least a portion of the capsule and configured to protect the capsule form stomach acid while allowing degradation of the capsule in the small intestine of the gastrointestinal tract; a plurality of functionalized particles disposed within the capsule, a plurality of tissue penetrating members configured to puncture a wall of the lumen of the intestinal tract; and an actuator having a first configuration and a second configuration. The actuator is configured to retain the plurality of functionalized particles within the capsule in the first configuration. The actuator is further configured to advance the plurality of functionalized particles from the capsule into a wall of the lumen of the gastrointestinal tract via the plurality of tissue penetrating members by the actuator transitioning from the first configuration to the second configuration.
The present disclosure relates to a monolithic thin-film lead assembly and methods of microfabricating a monolithic thin-film lead assembly. Particularly, aspects of the present disclosure are directed to a monolithic thin-film lead assembly that includes a cable having a proximal end, a distal end, a supporting structure that extends from the proximal end to the distal end, and conductive traces formed on a portion of the supporting structure. The supporting structure includes one or more layers of dielectric material. The monolithic thin-film lead assembly further includes an interface formed on the supporting structure at the distal end of the cable. The interface includes electrodes and/or sensors in electrical connection with the conductive traces, and the supporting structure has at least one curved portion disposed between a first set of electrodes and a second set of electrodes, and/or between a first set of sensors and a second set of sensors.
A computer system may perform an image-related function using segmentation (e.g., an image mask). To begin, the system may receive image data corresponding to a surgical scene including a background that includes an anatomical feature and at least one surgical tool. The system may also generate segmentation data using a first machine learning model based on inputting the first image data to the first machine learning model. The system may also include generating a segmentation of the at least one surgical tool using the segmentation data. Once the segmentation has been generated, the system may perform an image-related function using the segmentation.
A computer system may perform an image-related function using a segmentation (e.g., an image mask) that has been generated by a custom segmentation machine learning model. To begin, the system may receive image data corresponding to a surgical scene including a background that includes an anatomical feature and at least one surgical tool. The system may also generate segmentation data using the custom segmentation machine learning model based on inputting the first image data to the custom segmentation machine learning model. The system may also include generating a segmentation of the at least one surgical tool using the segmentation data. Once the segmentation has been generated, the system may perform an image-related function using the segmentation.
G06V 10/764 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant la classification, p.ex. des objets vidéo
88.
DYNAMIC SMOKE REDUCTION IN IMAGES FROM A SURGICAL SYSTEM
Systems and methods for de-smoking images of a surgical scene are described. Methods include receiving a video of a surgical scene including an image frame. Methods include determining that the image frame includes a smoke occlusion. Methods include determining an estimated un-occluded color of one or more pixels of the image frame using a lookup table, the lookup table mapping between a color space and a set of color bins including the estimated un-occluded color. Methods include determining a respective estimated true color for the one or more pixels of the subset using the imaged color, the estimated un-occluded color, and the smoke color. Methods also include generating a de-smoked image frame using the respective estimated true colors of the one or more pixels, the de-smoked image exhibiting a reduction of the smoke occlusion relative to the image frame.
Systems and methods for de-smoking images of a surgical scene are described. Methods include receiving a video of a surgical scene including an image frame. Methods include determining that the image frame includes a smoke occlusion. Methods include determining an estimated un-occluded color of one or more pixels of the image frame using a lookup table, the lookup table mapping between a color space and a set of color bins including the estimated un-occluded color. Methods include determining a respective estimated true color for the one or more pixels of the subset using the imaged color, the estimated un-occluded color, and the smoke color. Methods also include generating a de-smoked image frame using the respective estimated true colors of the one or more pixels, the de-smoked image exhibiting a reduction of the smoke occlusion relative to the image frame.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
A technique for imaging a retina with a retinal camera includes illuminating the retina with a plurality of distinct illumination bands that are substantially exclusive of green visible light while substantially not illuminating the retina with the green visible light. A first retinal image is acquired while illuminating the retina with the distinct illumination bands and substantially not illuminating the retina with the green visible light.
A61B 3/14 - Dispositions spécialement adaptées à la photographie de l'œil
A61B 3/18 - Agencement de plusieurs appareils pour tester ou examiner les yeux
A61B 3/12 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour examiner le fond de l'œil, p.ex. ophtalmoscopes
H04N 23/15 - Génération des signaux d'image avec des circuits pour éviter ou corriger le mauvais recalage d'image
H04N 23/56 - Caméras ou modules de caméras comprenant des capteurs d'images électroniques; Leur commande munis de moyens d'éclairage
91.
METHODS AND SYSTEMS FOR POINT-OF-CARE SYNTHESIS AND ADMINISTRATION OF PARTICLE-BASED THERAPEUTICS
The present disclosure is related to an apparatus and system for synthesizing and administering particle-based therapeutics at the point-of-care. The apparatus includes a first chamber for receiving a first solution including lipids in a first solvent, a second chamber for receiving a second solution including nucleic acids in a second solvent, a mixing channel in communication with the first chamber and the second chamber, and a delivery system in communication with the to the mixing channel. The first solution in the first chamber and the second solution in the second chamber can be introduced into the mixing channel. The particle-based delivery system form in the mixing channel and the nucleic acids adhere to the particles. The formulated particle-based therapeutics are passed through a delivery system to a subject for administration.
B01F 23/45 - Mélange, p.ex. dispersion ou émulsion, selon les phases à mélanger Émulsion en utilisant le mélange à écoulement
B01F 23/40 - Mélange, p.ex. dispersion ou émulsion, selon les phases à mélanger Émulsion
B01F 25/433 - Tubes de mélange dans lesquels la forme du tube influence le mélange, p.ex. tubes de mélange ayant une section transversale variable ou pourvus de profils s'étendant vers l'intérieur
Introduced here is a digital pill comprised of a capsule, an ingestible sensor, and a slot antenna. The ingestible sensor can be configured to generate a signal indicative of a characteristic of the living body in which the digital pill is located. Biometric data can be stored, at least temporarily, in a memory in the form of signal values. For example, the slot antenna may transmit biometric data to a computing device across a network on a periodic basis (e.g., every 5 minutes, 15 minutes, 60 minutes, etc.). Alternatively, the slot antenna may stream biometric data to a computing device across the network in real time.
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
One example system includes a biosensor applicator having a housing defining a cavity configured to receive and physically couple to a biosensor device, and to apply the biosensor device to a wearer; an applicator coil antenna oriented around a first axis; and a biosensor device including a biosensor coil antenna; a first wireless transceiver electrically coupled to the biosensor coil antenna; a Bluetooth antenna; and a second wireless transceiver coupled to the Bluetooth antenna; wherein the biosensor device is physically coupled to the biosensor applicator and positioned at least partially within the cavity; and wherein the applicator coil antenna is configured to wirelessly receive electromagnetic (“EM”) energy from a remote coil antenna and wirelessly provide at least a first portion of the received EM energy to the biosensor coil antenna.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
H04W 4/80 - Services utilisant la communication de courte portée, p.ex. la communication en champ proche, l'identification par radiofréquence ou la communication à faible consommation d’énergie
An analyte-sensitive substance is provided that has an optical property related to the concentration of an analyte. The analyte-sensitive substance includes an ionophore or other substance configured to provide a local pH, within the analyte-sensitive substance, that is related to the concentration of the analyte proximate the analyte-sensitive substance. The analyte-sensitive substance further includes a pH-sensitive fluorophore that increases or decreases its intrinsic fluorescence intensity with the local pH across a specified range of pH values. The analyte-sensitive substance further includes a pH-sensitive quencher configured to increase the slope of the change of fluorescence intensity of the pH-sensitive fluorophore across the specified range of pH values. The analyte-sensitive substance may further include an ionic additive configured to adjust the local pH such that the specified range of pH values corresponds to a range of analyte concentration values of interest.
The disclosed embodiments include a computer-implemented method for communications centric care. A caregiver interface serves a patient interface in accordance with a disease management program to collaboratively lead the patient to recover from a disease. The method can include obtaining content items relating to a patient and labeling each content item as either a secure content item or an unsecure content item, and then comparing the labels with identifiers of the patient, the caregiver, and/or a schedule key events of the disease management program. The content items are selectively bifurcated for the patient and/or caregiver interfaces. As such, the interfaces can manage communications in accordance with the disease management program.
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p.ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p.ex. pour la gestion du personnel hospitalier ou de salles d’opération
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients
H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p.ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
G06F 21/62 - Protection de l’accès à des données via une plate-forme, p.ex. par clés ou règles de contrôle de l’accès
G06Q 50/26 - Services gouvernementaux ou services publics
96.
Artificial Intelligence-Based Assistant For Concurrent Review Of Needle Core Prostate Biopsies
One example method includes receiving a digital image of a needle core prostate biopsy, displaying, using a display device, a magnified portion of the digital image, obtaining, from a deep learning model, Gleason scores corresponding to patches of the magnified portion of the digital image, and displaying, using the display device, a superimposed overlay on the magnified portion of the digital image based on the Gleason scores and corresponding confidence values of the Gleason scores, the superimposed overlay comprising one or more outlines corresponding one or more Gleason scores associated with the magnified portion of the digital image and comprising image patches having colors based on a Gleason score of the Gleason scores corresponding to an underlying portion of the magnified portion of the digital image and a confidence value of the corresponding Gleason score.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
09 - Appareils et instruments scientifiques et électriques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Downloadable software for patient case management for use by healthcare providers for the purpose of viewing and sharing patient health information, performing healthcare data analytics, generating patient insights, and managing patient care Providing temporary use of non-downloadable cloud-based software for patient case management for use by healthcare providers for the purpose of viewing and sharing patient health information, performing healthcare data analytics, generating patient insights, and managing patient care
98.
DIFFERENTIAL CHARGE-BALANCING DURING HIGH-FREQUENCY NEURAL STIMULATION
Differential charge-balancing can be used in high-frequency neural stimulation. For example, a neural stimulation apparatus can have first and second electrodes configured to be coupled proximate to a nerve fiber to implement a neural stimulation procedure. A neural stimulation circuit can be electrically coupled to the first and second electrodes. The neural stimulation circuit can apply stimulation currents to the nerve fiber through the first and second electrodes during a first stimulation phase of the neural stimulation procedure. The neural stimulation circuit can also apply a modified stimulation current to the nerve fiber through the first electrode during a second stimulation phase of the neural stimulation procedure. The modified stimulation current can be generated based on a difference between (i) a voltage at the first electrode, and (ii) a reference voltage derived from voltages on the first and second electrodes.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/06 - Electrodes pour traitement à haute fréquence
A sieving device is described. The sieving device includes an adjustable sieve surface that includes a first sieve surface and a second sieve surface. Openings are formed in each of the first sieve surface and the second sieve surface so as to define a shared pathways extending through the adjustable sieve surface. The shared pathways are defined by a length dimension that is greater than a width dimension. The width dimension can correspond to a cephalothorax width of an insect.
A male population of mosquito pupae sorted according to a sorting method is described. The sorting method may include adding a mixed population of mosquito pupae into an interior volume of a sieving container including base defining a set of openings enabling movement of mosquito pupae from the interior volume through the set of openings. The mixed population of mosquito pupae may include male mosquito pupae and female mosquito pupae. The method may also include adding a volume of aqueous solution to the interior volume. The method may also include removing a portion of the male pupae from the mixed population of mosquito pupae to by performing a sieving action that causes the portion of the male pupae and a portion of the volume of water to pass from the interior volume through the set of openings. The method may also include capturing the portion of the male pupae as the male population of mosquito pupae after the portion of the male pupae has passed through the set of openings.
