UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Arendt, Elke
Abrégé
A method of processing spent brewer's yeast (BSY) to a fermented BSY product is described. The BSY product is a pleasant tasting, nutritious and functional ingredient which enables the ingredient to be used for human consumption in foods and beverages. The method comprises autolysis of the BSY followed by lactic acid fermentation and optionally drying. The method reduces the bitterness drastically, removes RNA and alcohol significantly, and changes the sensory profile as well as the techno-functional properties of the fermented BSY. The resultant fermented BSY product is very high in protein and valuable dietary fibre and therefore follows the current trend to increase the intake of plant and mycoproteins and fibre.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Moore, Tom
Abrégé
The use of Fc-tagged Pregnancy-specific glycoprotein 1 (PSG1-Fc) in a method of treatment of a tendon injury in a human, in which the PSG1 is administered by intra-tendon or peri-tendon injection, is described. Also described is the use of CC49 in a method of treatment of tendonitis, tendinosis, tendinopathy, or tendon damage in an equine mammal, in which the CC49 is administered by intra-tendon or peri-tendon injection.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND (Irlande)
Inventeur(s)
Stamatas, Georgios N.
Sato, Takahiro
Oddos, Thierry
Hourihane, Jonathan
Irvine, Alan D.
Insel, Richard A.
Abrégé
A method to predict a propensity of an infant to develop atopic dermatitis. The method includes observing the expression of S100A8/A9 on a skin area of an infant; comparing the expression to determined standard, wherein the determined standard is ascertained by measuring a level of the biomarker in a subject or pool of subjects who have demonstrated an absence of atopic dermatitis; and determining the propensity of an infant to develop atopic dermatitis, wherein an increase in the expression as compared to the determined standard indicates propensity of the infant to develop atopic dermatitis.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
4.
WINDOW OF OPPORTUNITY SKIN TREATMENT REGIMEN AND COMPOSITION FOR PREVENTING THE ONSET OF OR TREATING ATOPIC DERMATITIS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Ouyang, Xing
Townsend, Paul
Abrégé
A method of estimating channel state information (CSI) of a Multiple Input Multiple Output (MIMO) channel includes transmitting pilot symbols from a plurality of transmission antennas, wherein a number of pilot symbols are transmitted using chirped signals based on the Fresnel transform for generating Orthogonal chirp-division multiplexing (OCDM) signals, the number of pilot symbols overlap in time-domain, a single symbol interval is utilized to estimate a transfer matrix of the MIMO channel, and no silent pilot symbols are transmitted.
The present invention provides a fetal monitoring device and method, and in particular a real time fetal pH, lactate and physiological monitoring device for detection and prevention of perinatal hypoxia, the device including an optical sensor operable to emit light at a wavelength of between 1050nm-3000nm onto vascularised tissue on the fetal scalp and to detect the reflected light, in addition to a processor operable to convert real time spectroscopy data from the reflected light into correlated real time data regarding one or more biological markers.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale
A61B 5/1464 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale spécialement adaptés pour des tissus fœtaux
A61B 5/01 - Mesure de la température de parties du corps
A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Pavlovic, Zoran
O'Driscoll, Séamus
Abrégé
A device (90) is disclosed, comprising: a first upper conducting layer (101) and second upper conducting layer (102); a first lower conducting layer (111) and second lower conducting layer (112); a core layer (131) between the first and second upper conducting layers (101, 102) and the first and second lower conducting layers (111, 112); a first via (121) connecting the first upper conducting layer (101) to the first lower conducting layer (111); a second via (122) connecting the second upper conducting layer (102) to the second lower conducting layer (112). The first via (121) and the second via (122) are concentric.
H01F 17/00 - Inductances fixes du type pour signaux
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
8.
POLYPEPTIDES CAPABLE OF LIMITING THE REPLICATION OF A CORONAVIRUS
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (Canada)
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (Canada)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Pelletier, Gerard
Girgis, Samer
Ragoussis, Ioannis
Oikonomopoulos, Spyridon
Vidal, Silvia
Malo, Danielle
Hobman, Tom
Xu, Zaikun
Baranov, Pavel
Fedorova, Alla
Abrégé
The present invention relates to polypeptides capable of limiting the replication of coronavirus and/ or nucleic acid molecules encoding polypeptides capable of limiting the replication of coronavirus, including those comprising a Nsp1-10 fusion and/or Nsp12. The present invention also relates to methods of using said polypeptides and/or nucleic acid molecules encoding said polypeptides for the treatment coronavirus infections in a subject in need thereof.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
LOUGHBOROUGH UNIVERSITY (Royaume‑Uni)
Inventeur(s)
Zargana, Karsan
Fernandez-Mato, Antonio
Holmes, Justin
Abrégé
A method of recycling a plastic product comprising PET is provided. The method comprises combining a plastic product comprising PET, a heterogeneous metal oxide catalyst and a solvent to provide a reaction mixture and heating the mixture by microwave irradiation to provide reaction product.
C08J 11/16 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p.ex. dévulcanisation par traitement avec une substance inorganique
C08J 11/24 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p.ex. dévulcanisation par traitement avec une substance organique par traitement avec des composés organiques contenant de l'oxygène contenant des groupes hydroxyle
10.
TREATMENT OF CEREBROVASCULAR EVENTS AND NEUROLOGICAL DISORDERS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Moore, Tom
Waeber, Christian
Abrégé
The invention provides a Pregnancy-specific glycoprotein (for example PSG1) for use in a method of treating neurological disorders or stimulating survival or recovery of tissue damaged by a cerebrovascular event or brain trauma in a subject. The PSG1 may be Fc-tagged PSG1.
A61K 38/17 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p.ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénal
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Moore, Tom
Clover, Anthony James Peterson
Abrégé
The use of Fc-tagged Pregnancy-specific glycoprotein 1 (PSG1-Fc) in a method of treatment of osteoarthritis or damaged cartilage in a human, in which the PSG1 is administered by intra-articular injection, is described. Also described is the use of CC49 in a method of treatment of osteoarthritis or damaged cartilage in an equine mammal, in which the CC49 is administered by intra-articular injection. (Fig. 3A-C) Also described is the use of PSG1 in a method of treatment of wounds, scarring, burns and diabetic ulcers in a mammal.
A61K 38/17 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p.ex. arthrites, arthroses
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
12.
LACTICASEIBACILLUS PARACASEI EM025-11 AND USES THEREOF
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
TEAGASC - THE AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (Irlande)
Inventeur(s)
O'Toole, Paul
Van Sinderen, Douwe
Ross, Paul
Melgar, Silvia
Abrégé
A strain of Lacticaseibacillus paracasei EM025-11 is described. The strain has an unusually broad catabolic activity including for prebiotics not normally utilized by commensal lactobacilli and is therefore suitable for inclusion in a synbiotic combination. The strain has also been found to adhere to but did not invade intestinal epithelial cells (IECs), which is an important probiotic trait (Fig. 1), and also demonstrates anti-inflammatory activity.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Caplice, Noel
Stanton, Catherine
Ross, Paul
Herisson, Florence
Karnik, Kavita
De Souza, Mervyn
Laurie, Ieva
Canene-Adams, Kirstie
Abrégé
Lactobacillus Lactobacillus mucosae and soluble dietary fiber, and methods treatment related thereto, useful against metabolic syndrome and related diseases, disorders and morbidities.
A23L 29/269 - Aliments ou produits alimentaires contenant des additifs; Leur préparation ou leur traitement contenant des agents gélifiants ou épaississants d'origine microbienne, p.ex. xanthane ou dextrane
A23L 33/135 - Bactéries ou leurs dérivés, p.ex. probiotiques
A23L 33/21 - Adjonction de substances essentiellement non digestibles, p.ex. de fibres diététiques
A61K 35/747 - Lactobacilles, p.ex. L. acidophilus ou L. brevis
15.
TUMOR SENSOR SYSTEM FOR TUMOR LOCALIZATION, THERAPY RESPONSE, AND IMAGE GUIDED SURGERY
STICHTING HET NEDERLANDS KANKER INSTITUUT - ANTONI VAN LEEUWENHOEK ZIEKENHUIS (Pays‑Bas)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Ruers, Theodoor Jacques Marie
Burke, Ray
Abrégé
A tumor sensor system comprising an implantable probe and an auxiliary device, the probe comprising at least one sensor configured to generate an electric signal in response to a physical stimulus, wherein the at least one sensor comprises a position sensor configured to sense a signal from a position tracking system wherein the sensed signal is indicative of a position of the probe in a space, wherein the position sensor comprises at least one electromagnetic sensor configured to cooperate with an external electromagnetic field generator, wherein the at least one electromagnetic sensor is configured to detect a property of the electromagnetic field and send it as an electric signal to the processing circuit, at least one antenna for data communication by means of inductive communication, an energy harvesting coil, and transmitting the data via the at least one antenna to the auxiliary device.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Sullivan, Mark
Temko, Andriy
O'Shea, Alison
Boylan, Geraldine
Popovici, Emanuel
Abrégé
The present invention relates to an integrated system and method for EEG signal acquisition and interpretation, for neonatal seizure detection. The system as per the present invention comprises a control device, an integrated circuit, a wireless communication module, a visual indication means, and a power management module. The control device has a Convolutional Neural Network (CNN) embedded on it, and is programmed to configure the integrated circuit to receive a plurality of channels of EEG data from a plurality of EEG acquisition electrodes, and to amplify and digitize the received EEG data. The integrated circuit is further configured to segment the channels of EEG data to a plurality of sequential epochs of EEG data. The control device is configured to pass the sequential epochs of EEG data through the CNN which is pre-trained to output the probability of a seizure in the EEG data passed through it. The channels of EEG data received from the acquisition electrodes and the probability of seizure outputted by the CNN is communicated to at least remote computing device by the communication module. A filter is applied to smooth the outputs in a post-processing routine. The visual indication means is enabled if the output of the CNN exceeds a predetermined threshold probability.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
UNIVERSITY COLLEGE DUBLIN (Irlande)
Inventeur(s)
Roche, Helen
O'Toole, Paul
Mitchelson, Kathleen
Tram, Tam
Vlckova, Klara
Abrégé
A whole (1→3)-β-D-glucan particle for treating or preventing a hepatic metabolic condition associated with obesity or diabetes in a subject is provided. The method comprises administering an effective amount of a whole (1→3)-β-D-glucan particle to said subject. The glucan is β-1,6 branched β-1,3 glucan.
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p.ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p.ex. antidiabétiques
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY IRELAND, CORK (Irlande)
Inventeur(s)
Corbett, Brian
Roycroft, Brendan
Abrégé
An optical power converter device (200, 300) comprises a semiconductor waveguide structure having a first end facet (F1) configured to receive an incident light beam, and one or more light absorbing layers (210a) with a total thickness of substantially less than 100 nm and configured to absorb light guided by the waveguide structure. The device further comprises a cathode (202) and an anode (204) in contact with substantially the entire length of the waveguide structure in the direction of propagation of light from the first end facet for outputting generated electrical power. An optical power converting system (1000) comprising the optical power converter device is also provided, as is a method of operating the optical power converter.
H01L 31/0232 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails - Détails Éléments ou dispositions optiques associés au dispositif
G02B 6/122 - Elements optiques de base, p.ex. voies de guidage de la lumière
H01L 31/0304 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIIIBV
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
19.
A METHOD OF PREDICTING THE RISK OF SPONTANEOUS PRE-TERM BIRTH (SPTB)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Considine, Elizabeth
Dowling, Kirsten
Abrégé
A method for predicting the risk of spontaneous pre-term birth in a patient comprising assaying a biological sample obtained from the patient (at 20 weeks gestation) for abundance of at least one metabolite biomarker.
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Duane, Russell
Jaksic, Aleksandar
Vasovic, Nikola
Abrégé
The present invention provides a radiation dosimeter with improved sensitivity. The sensor apparatus comprises a semiconductor structure, a means for biasing the semiconductor structure to readout stored charge in its dielectric by exhibiting a sensor current-voltage characteristic which is proportional to the dielectric stored charge, and a means for determining a change in current- voltage characteristic of the sensor terminal due to irradiation. The semiconductor substrate comprises a bulk region of a first conductivity type formed in the substrate, a source region and a drain region formed in the bulk region, wherein the source region and the drain region are of a second conductivity type opposite to the first conductivity type, a channel region formed between the source region and the drain region, a dielectric formed on the channel region for storing charge due to irradiation, and a gate electrode formed on the dielectric. The means for biasing configures the semiconductor structure such that the gate electrode and the source region are electrically connected to form a sensor terminal, and the bulk is biased with a fixed voltage such that it is reverse biased with respect to the sensor and the drain, and the drain is biased with a fixed voltage such that it sinks channel current sourced from the sensor terminal, and wherein the channel region is configured to provide a channel current from the sensor to the drain which is larger in magnitude than the reverse biased bulk-sensor and bulk-drain diode currents.
H01L 31/119 - Dispositifs sensibles au rayonnement d'ondes très courtes, p.ex. rayons X, rayons gamma ou rayonnement corpusculaire caractérisés par un fonctionnement par effet de champ, p.ex. détecteurs du type MIS
H01L 31/02 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails - Détails
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Zubialevich, Vitaly, Z.
Parbrook, Peter, J.
Pampilli, Pietro
Abrégé
A semiconductor heterostructure device for use as a component in an optoelectronic component, the device has a substrate, a nanocolumn extending from the substrate, a self-centred passivation layer on top of the nanocolumn, an active region which comprises a quantum well (QW) stack on a vertical side of the nanocolumn and wherein the passivation layer extends horizontally outwards from the nanocolumn to overhang the nanocolumn and the QW stack. The device provides for efficient NC heterostructure based light emitting diodes (LEDs) and other optoelectronic devices with an active region located purely on non-polar facets of the NCs. It also eliminates parasitic current paths allowing core-shell nanorod-based LEDs with emission from the desired facets only.
H01L 33/24 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué de la région électroluminescente, p.ex. jonction du type non planaire
H01L 33/18 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure cristalline ou une orientation particulière, p.ex. polycristalline, amorphe ou poreuse au sein de la région électroluminescente
H01L 31/0392 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur structure cristalline ou par l'orientation particulière des plans cristallins comprenant des films minces déposés sur des substrats métalliques ou isolants
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
H01L 33/08 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une pluralité de régions électroluminescentes, p.ex. couche électroluminescente discontinue latéralement ou région photoluminescente intégrée au sein du corps semi-conducteur
H01L 33/44 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les revêtements, p.ex. couche de passivation ou revêtement antireflet
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Brien, Peter
Abrégé
The present disclosure is directed towards aligning a photonic integrated circuit (PIC) through providing a PIC with a marker waveguide, wherein a marker waveguide is a waveguide having: a first end located at the edge of the PIC wherein the first end is coupled to an edge coupling; and a second end coupled to a grating coupler or a device coupler, wherein: the grating coupler or device coupler is configured to receive light and couple the light to the waveguide to illuminate the waveguide to facilitate the correct alignment of the edge coupler to an external component.
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
G02B 6/124 - Lentilles géodésiques ou réseaux intégrés
G02B 6/30 - Moyens de couplage optique pour usage entre fibre et dispositif à couche mince
G02B 6/42 - Couplage de guides de lumière avec des éléments opto-électroniques
23.
AN OPTICAL FIBER CATHETER PROBE AND A MANUFACTURING METHOD THEREOF
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Brien, Peter
Abrégé
The catheter probe comprises a catheter tip and a catheter body. The catheter tip comprises a plurality of channels for housing a plurality of optical sensors. Each one of said plurality of optical sensors comprises a ferrule comprising a via, a microlens aligned with said via and attached to said ferrule and an optical fiber for optically coupling said microlens to a monitoring means.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
The invention relates to a variant nisin peptide, wherein the variant nisin peptide is a modified variant of wild-type nisin, wherein the modification comprises or consists of an amino acid residue modification selected from: i) M17Q or M17A; ii) T2L; and iii) one set of modified hinge residues selected from a) N20H and M21T, b) N20V, M21G, and K22A, c) N20V, M21G, and K22V or d) N20V, M21G, and K22T; or v) combinations of modifications i), ii), and iii), and related medical uses and products comprising such nisin peptides.
C07K 14/315 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Streptococcus (G), p.ex. Enterocoques
A23L 3/3526 - Composés organiques contenant de l'azote
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Konugolu Venkata Sekar, Sanathana
Andersson-Engels, Stefan
Matias, Jean
Komolibus, Katarzyna
Abrégé
An apparatus and method for performing optical characterisation of luminescent particles within a sample is provided. The apparatus comprises a light source (10) configured to produce a first pump beam having a first centre wavelength and a substantially speckle-free beam profile for illuminating, along a first illumination optical (path (101), a sample to thereby produce emitted light by the interaction of the first pump beam with the sample; a first detector (70E) for detecting pump-induced emitted light from a detection region (65) within the sample along a first detection optical path (102); and a first optical filter element in the first detection optical path (102) for attenuating light at the first centre wavelength. The method comprises illuminating the sample with the pump beam having the substantially speckle-free beam profile at a detection region (65) within the sample; and detecting light emitted from the detection region of the sample produced by the interaction of the pump beam with the sample.
G02B 27/09 - Mise en forme du faisceau, p.ex. changement de la section transversale, non prévue ailleurs
G02B 27/48 - Systèmes optiques utilisant la granulation produite par laser
G01N 15/00 - Recherche de caractéristiques de particules; Recherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux
G01N 15/10 - Recherche de particules individuelles
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Toole, Paul
Jeffery, Ian
Ghosh, Tarini
Tan, Huizi
Perez, Marta
Ntemiri, Alexandra
Abrégé
Coprococcus catus, Eubacterium rectale, Alistipes putredinis, Barnesiella intestinihominis, Roseburia hominis, Dorea longicatenaFaecalibacterium prausnitziiFaecalibacterium prausnitzii. Also provided are specific isolated bacterial strains and use of the composition for treating frailty and/or inflammation related to aging in elderly subjects.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Riza, Nabeel, Agha
Abrégé
The present invention provides a method for performing optical image detection using a camera module comprising a Digital MicroMirror Device, a first point Photo Detector, a second point Photo Detector, a first lens and a second lens. The method comprises: mapping incident light onto an image plane of the DMD to form a light irradiance map; selecting N pixels on the DMD for time frequency coding; associating each selected pixel with a unique Walsh code time sequence; time frequency coding by the DMD the optical irradiance values of each selected pixel using a plurality of selected bits of its associated Walsh code time sequence; detecting the time frequency coded optical irradiance values of the selected pixels simultaneously at the first point Photo Detector and at the second point Photo Detector; and performing simultaneous signal processing on the time frequency coded optical irradiance values detected by the first point Photo Detector and by the second point Photo Detector to determine the light intensity of each of the selected pixels and produce an image of the incident light.
H04N 5/335 - Transformation d'informations lumineuses ou analogues en informations électriques utilisant des capteurs d'images à l'état solide [capteurs SSIS]
G01S 17/89 - Systèmes lidar, spécialement adaptés pour des applications spécifiques pour la cartographie ou l'imagerie
28.
METHOD FOR PRODUCING POROUS GRAPHENE OR POROUS GRAPHTIC CARBON
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Burke, Michael
Quinn, Aidan
Iacopino, Daniela
Manning, Mary
Abrégé
A method is provided for producing a porous graphene or porous graphitic carbon material. The method comprised creating a biopolymer-based feedstock material from a biopolymer formulation (8). The bio polymer is derived from a synthetic or naturally occurring mucopolysaccharide or other heteropolysaccharide. The method comprises irradiating the biopolymer-based feedstock material with coherent light (12) to produce porous graphene or porous graphitic carbon.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Faisal, Waleed
Crean, Abina
Abrégé
A microneedle with very high drug loading is described, and comprises a base and a penetrating tip, the tip having a dimension ranging from about 50 nm to about 50 µm, wherein at least 80 % of the microneedle by volume consists of heat-meltable active pharmaceutical ingredient (v/v). The meltable active pharmaceutical ingredient is characterised by being heat-meltable (i.e. it can be heated to a molten form), is solid at 25°C, and has an ability to form a glassy, amorphous form following melting by heating and cooling with a glass transition temperature greater than 25°C. A method of fabricating a microneedle comprises the steps of providing a microneedle micromold comprising a micromold substrate and one or more holes in the upper surface of the micromold substrate, wherein the interior surface of the hole in the micromold substrate defines an exterior surface of the microneedle, moulding a meltable drug in the microneedle micromold to form a microneedle, and separating the microneedle from the microneedle micromold. Microneedles of the invention may incorporate up to 99% drug or more.
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p.ex. rifampine, thiothixène
A61K 31/565 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrène; Leurs dérivés, p.ex. stéroïdes non substitués en position 17 bêta par un atome de carbone, p.ex. œstrane, œstradiol
UNIVERSITY COLLEGE CORK – NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
JANSSEN BIOTECH, INC. (USA)
Inventeur(s)
Plevy, Scott
Hill, Colin
Shkoporov, Andrey
Clooney, Adam
Sutton, Thomas
Abrégé
A method is described of analyzing the microbiome, including the virome, of a patient. Viral marker clusters for diagnosing inflammatory bowel disease, Crohn's disease and ulcerative colitis are identified from such analysis. Methods of diagnosis and treatment of dysbiosis and various disorders, such as inflammatory bowel disease, Crohn's disease and ulcerative colitis, are also included.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Ross, Paul
Stanton, Catherine
Abrégé
A composition for use in a method of regulating or treating a metabolic disease or a symptom thereof, the composition comprising an isolated bacteria Lactobacillus brevis (DPC6108) deposited with the National Collection of Industrial and Marine Bacteria Limited (NCIMB) on 28 November 2011 and accorded the accession number NCIMB 41903.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
TEAGASC, THE AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (Irlande)
Inventeur(s)
Ross, Reynolds Paul
Stanton, Catherine
Hill, Colin
Ryan, Anthony
O'Sullivan, Julie
Watkins, Claire
Abrégé
An isolated lantibiotic is provided comprising amino acid sequence SEQ. ID No. 2 and at least one of amino acid sequences SEQ. ID No. 4 and SEQ. ID. No 6. Also provided is use of the lantibiotic in the treatment or prevention of infection by Group B Streptococcus or Corynebacterium xerosis. The invention further relates to isolated S. hominis strains and use of same in producing the lantibiotic. A vector is provided comprising nucleotides sequences for producing the lantibiotic.
A61K 38/16 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés
C07K 14/31 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Micrococcaceae (F) provenant de Staphylococcus (G)
33.
A VERTICAL MAGNETIC STRUCTURE FOR INTEGRATED POWER CONVERSION
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Mathuna, Cian
Smallwood, Daniel
Pavlovic, Zoran
Smiddy, Hugh
O'Driscoll, Seamus
Mccloskey, Paul
Abrégé
The present invention provides an inductor device comprising one or more interconnected columns of conductive material embedded in a supporting structure, wherein the one or more columns comprise an input terminal and an output terminal; and wherein each column is surrounded by a first magnetic layer.
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
H05K 1/16 - Circuits imprimés comprenant des composants électriques imprimés incorporés, p.ex. une résistance, un condensateur, une inductance imprimés
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Maguire, Anita
Gavin, Declan
O'Gara, Fergal
Reen, Jerry
Abrégé
An isolated w-transaminase enzyme comprising an amino acid sequence of SEQUENCE ID NO: 1, or encoded by a nucleic acid sequence of SEQUENCE ID NO: 2, is provided which is derived from marine sponge Pseudovibrio sp.. Also provided are functional variants of the w-transaminase enzyme that are isolated, have at least 80% sequence identity with SEQUENCE ID NO: 1, and are capable of enantioselectively resolving a racemic amine by transformation to a ketone by oxidative deamination, or enantioselectively resolving a racemic ketone by transformation to an amine by reductive amination, in which the amine and ketone typically contain a stereocentre removed from the reacting site. An example of a functional variant is SEQUENCE ID NO:3. In one embodiment, the functional variant is capable of enantioselectively transforming a (4S) -tetralone intermediate in the synthesis of sertraline, in which the functional variant displays remote stereospecificity for the tetralone intermediate.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Peters, Frank
Duggan, Shane
Abrégé
The invention provides an optical system and method for outputting a modulated signal comprising a single multimode interference (MMI) device having at least two inputs configured with a fixed phase and an output, wherein the output modulated signal is controlled by modulating the input power of at 5 least one of the inputs. The invention only requires a single MMI device to operate as the relative phase between the two inputs are fixed relative each other and one of the inputs can be used to modulate the output by modulating the power at a single input. In further embodiments, the invention shows how correct phases can be set by a single MMI device. Thus, no more than two 10 MMIs are required in conjunction with phase or amplitude modulating elements to fully generate a BPSK or QPSK signal.
H04B 10/556 - Modulation numérique, p.ex. modulation par déplacement de phase différentielle [DPSK] ou modulation par déplacement de fréquence [FSK]
G02F 1/225 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p.ex. commutation, ouverture de porte ou modulation; Optique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur par interférence dans une structure de guide d'ondes optique
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Mahony, Conor
O'Callaghan, Suzanne
Abrégé
An intelligent laminate dressing system (1) for monitoring and treating a wound made up an absorbent pad (2), a sensor (16) for detecting wound data and an electronic module (17) communicable with the sensor (16), the sensor (16) and the electronic module (17) being positionally offset with respect to the centre of the absorbent pad (2).
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Morris, Michael A.
Padmanabhan, Sibu C.
Kerry, Joseph P.
Cruz-Romero, Malco
Abrégé
A coating composition for applying a very thin film coating to a substrate such as a polymeric film comprises a copolymer such as a block copolymer (BCP) that is compatible with the substrate, an alcohol solvent or solvents capable of dissolving the copolymer, a hydrolysed metal alkoxide precursor, a carboxylic acid stabiliser, and an active agent in an ionic, molecular, or small nanoparticle form. The active agent is configured to provide a functionality to the coating composition, selected from antimicrobial, antifungal, barrier, therapeutic, electrical, electronic, magnetic and optical. The composition is a sol comprising a continuous non-sedimentable/stable suspension of very small sized (of nano order) amorphous inorganic polymers in their oligomeric or polymeric state, and comprising the active agent dispersed in a hydrolysed metal alkoxide-BCP matrix. Substrates coated with very thin coatings are also provided, including coated LDPE which is activated before coating by UV/ozone, plasma or corona treatment prior to deposition of a wetting layer.
C09D 1/00 - Compositions de revêtement, p.ex. peintures, vernis ou vernis-laques, à base de substances inorganiques
C09D 5/00 - Compositions de revêtement, p.ex. peintures, vernis ou vernis-laques, caractérisées par leur nature physique ou par les effets produits; Apprêts en pâte
C09D 5/14 - Peintures contenant des biocides, p.ex. fongicides, insecticides ou pesticides
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Donadei, Agnese
Flynn, Olivia
Moore, Anne
Abrégé
A composition for stabilising a vaccine in a solid dosage format is provided wherein the composition comprises an antioxidant, such as glutathione, a monosaccharide or disaccharide sugar, such as trehalose, a polyol sugar, such as sorbitol, one or more salts, such as magnesium chloride and sodium glutamate, and a vaccine. The composition may also comprise an aqueous soluble polymer, such as polyvinyl alcohol (PVA). A preferred composition comprises 40 mM glutathione,20% w/v trehalose,3% w/v sorbitol, 1.5% w/v PVA,3% w/v magnesium chloride and 3% w/v sodium glutamate. Also provided is a method of stabilising a vaccine in a solid dosage format, the method comprising drying the stabilising composition to provide the vaccine in the solid dosage format. The composition and method may be used to stabilise any suitable vaccine, such as poliovirusor adenovirus, in a solid dosage format, such as microneedle patches or wafers.
C08L 29/04 - Alcool polyvinylique; Homopolymères ou copolymères d'esters partiellement hydrolysés d'alcools non saturés avec des acides carboxyliques saturés
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Walter, Thomas
Abrégé
A peptide comprises an amino acid sequence of SEQUENCE ID NO. 1, in which the sequence has 1, 2 or 3 amino acid changes. The peptide has utility in treatment of cardiovascular disease and neurodegenerative disease.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Stanton, Catherine
Ross, Paul
Fitzgerald, Ger
Ryan, Tony
Abrégé
A composition comprises a cohort of at least five isolated unique strains of a single species of bacteria, wherein the species of bacteria is represented in the mammalian microbiome, and wherein the cohort of isolated strains exhibit different and diverse catabolic capability thereby increasing the chances that one or more of the strains in the composition will find a nutritional niche in the infant GI tract.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
ALTRATECH LIMITED (Irlande)
Inventeur(s)
Cummins, Timothy
O'Farrell, Brian
Darby, Steven
O'Connell, Ivan
Abrégé
A diagnostic sensor device (1) has a semiconductor chip (2) having a distal end physically configured to fit into a power and data socket (10) conforming to a non-proprietary standard, and having exposed pads (3) for engagement with corresponding conductors of such a socket. At its proximal end the chip has at least one sensor (5) for contact with an analyte. The device may be manufactured in a single integrated process to provide a wafer (9) which is diced to provide the individual devices.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Cryan, John
Dinan, Ted
Stanton, Catherine
Schellekens, Harriet
Torres, Cristina
Roy, Bernard
Abrégé
Bifidobacterium longumin-vivoin-vivo, achieved through inducing satiety via decreased internalisation of the Ghrelin receptor, and therefore, decreased constitutive activity. Moreover, the strain also showed a trend towards decreased ghrelin receptor hypothalamic expression in HFD-fed mice when compared with vehicle control group. The strain also improves glucose tolerance and decreased insulin plasma levels in mice, indicating the strain in the prevention and/or treatment of Type II diabetes, especially in obese individuals.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND CORK (Irlande)
Inventeur(s)
O'Brien, Peter Andrew
Duperron, Matthieu Francois Gabriel
Burke, Ray
Eason, Cormac James
Manley, Kevin
Nunan, Gerard
Abrégé
A surgical system for penetrating and determining a characteristic of tissue. An instrument generates rotational torque, and a drill bit tool body extends along an axis between a distal end to engage tissue and a proximal end to couple to the instrument. An emitter operatively coupled to the instrument emits light. A detector operatively coupled to the instrument detects light. An emission lightguide within the tool body transmits light emitted by the emitter toward the tissue as the instrument rotates the tool body. A detection lightguide within the tool body is spaced from the emission lightguide and transmit light reflected by the tissue toward the detector as the instrument rotates the tool body. The emitter emits light into the emission lightguide along the axis, and the detector detects light reflected from the tissue exiting the detection lightguide transverse to the axis when the tool body is coupled to the instrument.
A61B 17/16 - Ostéoclastes; Forets ou ciseaux pour os; Trépans
B23B 49/00 - Systèmes de mesure ou de calibrage des machines à aléser, pour le positionnement ou le guidage du foret; Dispositif pour indiquer les défauts des forets pendant l'alésage; Dispositifs à centrer les trous à aléser
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Dwyer, Colm
Abrégé
The invention provides plastic 3D printed battery cell comprising a first layer coupled with a cathode material and a second layer coupled with an anode material. An aqueous electrolyte gel material is deposited onto the surface of the cathode material and the anode material, wherein the first and second layers are sealed to house the cathode material, the anode material and the electrolyte gel material. The invention provides a combination of a customisable plastic battery cell design using 3D printing with an all-in-one gel electrolyte enable the cells to be built in a variety of sizes and shapes allowing for greater integration of energy storage into electronic, medical or wearable systems. A method for making the 3D printed battery cell is also described.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
H01M 4/131 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif Électrodes pour accumulateurs à électrolyte non aqueux, p.ex. pour accumulateurs au lithium; Leurs procédés de fabrication Électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p.ex. LiCoOx
H01M 4/1391 - Procédés de fabrication d'électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p.ex. LiCoOx
H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p.ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p.ex. LiTi2O4 ou LiTi2OxFy
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p.ex. liants, charges
H01M 2/06 - Dispositions pour introduire des connecteurs électriques dans ou à travers des bacs
H01M 10/0565 - Matériaux polymères, p.ex. du type gel ou du type solide
H01M 10/056 - Accumulateurs à électrolyte non aqueux caractérisés par les matériaux utilisés comme électrolytes, p.ex. électrolytes mixtes inorganiques/organiques
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Caplice, Noel
Abrégé
An intravascular cell therapy device comprises a scaffold (2, 12) that is radially adjustable between a contracted orientation suitable for transluminal delivery to a vascular locus and an expanded orientation, and a biodegradable matrix provided on at least a portion of the scaffold that is suitable for seeding with cells and degrades in a vascular environment. The scaffold is configured to have a distal piercing tip (5) when in a deployed orientation. The scaffold comprises a plurality of sidewall panels (3, 13, 14) arranged around a longitudinal axis of the scaffold, and adjustable couplings (4) between the panels configured for adjustment between an expanded configuration and a contracted orientation, and in which each sidewall panel comprises a matrix suitable for seeding with cells.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Riza, Nabeel
Abrégé
The present invention provides a method for performing high dynamic range low inter- pixel spatial and wavelength crosstalk optical image detection in a camera comprising an Optical Array Device (OAD), a point Photo Detector (PD) and a Photo Detector Array (PDA) sensor. The method comprises imaging incident light from an object onto an image plane of the Optical Array Device (OAD) to form an incident image map; selecting by the OAD and the Point Photo Detector and by the OAD and the Photo Detector Array a plurality of pixels on the incident image map for time-frequency coding; time-frequency coding the selected pixels by the OAD; detecting by the point PD the optical irradiance values of the time-frequency coded pixels output from the OAD; and performing signal processing on the detected optical irradiance values to determine the light intensity of each of the selected pixels.
G02B 26/08 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander la direction de la lumière
H04N 5/335 - Transformation d'informations lumineuses ou analogues en informations électriques utilisant des capteurs d'images à l'état solide [capteurs SSIS]
H04N 5/238 - Circuits pour la compensation des variations de la luminance de l'objet en agissant sur la partie optique de la caméra
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Mahony, Conor
O'Flynn, Brendan
Galvin, Paul
Fleming, Mark
Abrégé
The invention provides a dressing system for a wound comprising an absorbent pad; at least one sensor for detecting wound or dressing data, wherein the at least one sensor is a moisture sensor; a flexible electronic circuit communicable with the sensor; a backing film adapted to cooperate with the absorbent pad, wherein the electronic circuit and the at least one sensor is printed directly on the backing film; and a communications module adapted to communicate the wound data from the electronic circuit to a user or clinician. The invention provides a simple to use disposable dressing wound system that is effective in providing dressing wound data that provides an indicator of the status of the wound as well as information that the dressing wound system needs to be replaced.
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Hill, Colin
Ross, Paul
Rea, Mary Clare
Alemayehu, Debebe
Murphy, Eileen Frances
Abrégé
Lactobacillus gasseri APC678 is effective against C. difficile colonisation or infection. Clostridium difficile is one of the most common causes of health-care acquired diarrhoea, resulting in a spectrum of disease from mild diarrhoea to life-threatening illness.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Darcy, Raphael
O'Driscoll, Caitriona
Malhotra, Meenakshi
Abrégé
A cyclodextrin-RNA conjugate is described in which the cyclodextrin molecule is conjugated at its glucosyl 6-, 2- or 3-positions, optionally via a linker, to at least one RNA molecule at the RNA 3' terminal base. The at least one RNA molecule may be an siRNA molecule.
A61K 47/61 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique macromoléculaire, p.ex. une molécule oligomérique, polymérique ou dendrimérique le composé organique macromoléculaire étant un polysaccharide ou l’un de ses dérivés
A61K 47/62 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant une protéine, un peptide ou un acide polyaminé
A61K 47/69 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament le conjugué étant caractérisé par sa forme physique ou sa forme galénique, p.ex. émulsion, particule, complexe d’inclusion, stent ou kit
51.
METHODS OF DETERMINING COLORECTAL CANCER STATUS IN AN INDIVIDUAL
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Connell Motherway, Mary
Van Sinderen, Douwe
Shanahan, Fergus
Abrégé
A recombinant gram positive commensal bacterium engineered for heterologous expression of Tad pilus. The Tad pilus is a Tad pilus from a Bifidobacterium selected from Bifidobacterium breve and Bifidobacterium longum. The bacterium is additionally engineered for heterologous expression in-situ in the human gut of a soluble biopharmaceutical product such as a cytokine, an enzyme, a hormone, and an antibody or antibody fragment. The invention also provides a method of treating an inflammatory disease of the human gut comprising administering a recombinant gram positive commensal bacterium of the invention, whereby the recombinant bacterium colonises the patients gut and effects in-situ expression of a soluble biopharmaceutical product in the patient's gut.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Connell Motherway, Mary
Van Sinderen, Douwe
Shanahan, Fergus
Houston, Aileen
Abrégé
The invention describes peptide, and proteins and fusion proteins comprising the peptides, that are capable of increasing the proliferation of cells, especially epithelial cells in the mammalian gastrointestinal tract. The peptides comprise the hydrophilic domain of the TadE subunit of the Tad pilus of Bifidobacterium, especially the pilus encoded by the Tad2003 gene cluster identified in Bifidobacterium breve UCC2003, and functional fragments of the hydrophilic domain. The invention informs new treatments for diseases and conditions that involve attenuated epithelial cell proliferation and growth, such as inflammatory conditions of the gastrointestinal tract and trauma of the skin including burns and other wounds. The invention also informs treatments of newborn babies to promote proliferation and growth of gut epithelial tissue by administration of agents comprising the peptide of the invention in the form of infant formula.
C07K 14/345 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Brevibacterium (G)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Jackson, Nathan
Mathewson, Alan
Olszewski, Zbigniew
Abrégé
The invention provides a monolithic integrated mesh device for atomization or pumping of a fluid or liquid comprising a plurality of apertures and a piezoelectric material. The piezoelectric material is bonded to the mesh device at an atomic scale. In one embodiment the monolithic micro-fabricated device of the invention includes piezoelectric material that eliminates the need for expensive assembly process and improves reliability. This also has advantage of requiring lower operating voltage and less complicated circuitry.
B05B 17/06 - Appareils de pulvérisation ou d'atomisation de liquides ou d'autres matériaux fluides, non couverts par les autres groupes de la présente sous-classe opérant suivant des procédés particuliers utilisant des vibrations ultrasonores
A61M 11/00 - Pulvérisateurs ou vaporisateurs spécialement destinés à des usages médicaux
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Mokarian-Tabari, Parvaneh
Morris, Michael
Senthamaraikannan, Ramsankar
Abrégé
The invention provides a solution based process based on high molecular weight block copolymer (BCP) nanolithography for fabrication of periodic structures on large areas of optical surfaces. In one embodiment there is provided method of fabricating a nano-patterned surface for application in a photonic, optical or other related device, said method comprising the steps of: providing a substrate material; depositing a block copolymer (BCP) material on the substrate material; and phase separating the BCPs using at least one solvent selected to facilitate polymer chain mobilisation and lead to phase separation to fabricate said nano-patterned surface; wherein the nano-patterned surface comprises an ordered array of structures and having a domain or diameter of 100nm or greater. A new photonic device and optical device is also described.
H01L 31/00 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails
H01L 33/00 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Mihatsch, Walter
Kelly, Phil
Proos, Sinead
Abrégé
A dairy product produced by a method comprising steps of: a) passing skim milk through an ultrafiltration membrane to produce an ultrafiltration permeate; and b) combining one part of the ultrafiltration permeate with whole milk; wherein the dairy product is low in protein and retains total solids content similar to a cow's milk.
A23C 9/142 - Préparations à base de lait; Lait en poudre ou préparations à base de lait en poudre dans lesquelles la composition chimique du lait est modifiée par des traitements non chimiques par dialyse, osmose inverse ou ultrafiltration
57.
A METHOD FOR THE PRODUCTION OF POLY(METHYL METHACRYLATE) (PMMA) MEMBRANES AND USES THEREOF
THE PROVOST, FELLOWS, FDN SCHOLARS, & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIV. TRINITY OF QUEEN ELIZABETH (Irlande)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Fleming, Peter
Morris, Michael
Fitzgerald, Thomas
Babu, Ramesh
Delaney, Paul
Ngan, Clifton
Hennesey, Niamh
Beyzavi, Kamran
Abrégé
A poly(methyl methacrylate) (PMMA) membrane having a highly porous, reticulated, 3-D structure suitable for lateral flow diagnostic applications is described. Also described is a method for producing a poly(methyl methacrylate) (PMMA) membrane that comprises the steps of mixing a suitable amount of PMMA, a solvent and a optionally one of either a co-solvent or a non-solvent to produce a solution, casting a thin film of the solution onto a support, and removal of the solvent from the solution to produce the PMMA membrane. A lateral flow diagnostic device comprising a highly porous PMMA membrane as a reaction membrane is also described.
A tunnel field effect transistor (100) comprises a source region (102), a drain region (104), and a channel region (106) formed of a single material, in particular a half-metal. The channel extends between the source region and the drain region. The channel region (106) and the drain region (104) are smaller than a threshold size in a first dimension. The threshold size is the size required for the material to exhibit sufficient quantum confinement such that a non-zero band gap results and the material becomes a semiconductor. The source region (102) is larger than this threshold size in the first dimension and is thus metallic.
H01L 29/739 - Dispositifs du type transistor, c.à d. susceptibles de répondre en continu aux signaux de commande appliqués commandés par effet de champ
H01L 29/06 - Corps semi-conducteurs caractérisés par les formes, les dimensions relatives, ou les dispositions des régions semi-conductrices
H01L 29/26 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, des éléments couverts par plusieurs des groupes , , , ,
B82Y 10/00 - Nanotechnologie pour le traitement, le stockage ou la transmission d’informations, p.ex. calcul quantique ou logique à un électron
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
A rectifying junction (15) is formed in a conduction path provided in a material (1). A size of the material (1) is smaller than a threshold size in a first dimension, the threshold size being the size required for the material (1) to exhibit sufficient quantum confinement such that it forms a semiconductor. A surface of a first region (17) of the material (1) is arranged to decrease the bandgap of the material such that the first region is conducting. A surface of a second region (19) of the material (1) is arranged to preserve a bandgap such that the second region is semiconducting. The second region (19) is contiguous to the first region (17), such that a rectifying junction (15) is formed at a boundary (21) between the first region and the second region.
B82Y 10/00 - Nanotechnologie pour le traitement, le stockage ou la transmission d’informations, p.ex. calcul quantique ou logique à un électron
B82Y 40/00 - Fabrication ou traitement des nanostructures
H01L 29/36 - Corps semi-conducteurs caractérisés par la concentration ou la distribution des impuretés
H01L 29/739 - Dispositifs du type transistor, c.à d. susceptibles de répondre en continu aux signaux de commande appliqués commandés par effet de champ
H01L 29/06 - Corps semi-conducteurs caractérisés par les formes, les dimensions relatives, ou les dispositions des régions semi-conductrices
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
60.
QUINOLINONE OR QUINAZOLINONE COMPRISING ANTIBIOFILM COMPOSITIONS, COMPOUNDS AND METHODS AND USES RELATING THERETO
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND (Irlande)
Inventeur(s)
O'Gara, Fergal
Reen, Jerry F.
Mcglacken, Gerard Patrick
Abrégé
An antibiofilm composition comprising a compound of formula (A1), (A2) or (A3): (A1) (A2) (A3) wherein each of R1, R2, R3, R4, R5, R6 and R7 is independently selected from hydrogen, alkyl, alkenyl, aryl, halo, alkoxy, hydroxyl, amino, nitro, sulfoxy, thiol, carboxy, alkyl carboxy and amido; and X may be 0 or S, wherein the composition does not comprise a compound of formula (B1) or (B2): (B1) (B2)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Zhao, Jian
Yu, Yukui
Abrégé
Provided is a method, system and apparatus for optical communications with encoded phase-conjugated twin wave or optical variant dual polarization optical signals through non-linear optical channels. A method of optical communication for an optical transmitter comprises generating, at a transmitter processor, at least two digital representations of at least two phase- conjugated optical variants carrying the same data payload for transmission; encoding, at an encoder, one of the at least two phase-conjugated optical variants encoded with additional information (Ea)to the data payload; and modulating, at an electrical to optical converter, the digital electrical signal into at least two phase conjugated optical variants. Also provided is a method of optical communication for an optical receiver comprising the steps of receiving, at an optical to electrical converter, at least two phase-conjugated optical variants with modulated data payloads, and one of the at least two phase-conjugated optical variants having a modulated data payload with additional information, and converting into corresponding digital representations of the at least two phase-conjugated optical variants; mapping, at a receiver processor, onto a constellation corresponding digital representations of the at least two phase-conjugated optical variants and selecting for de-mapping and determining the data payload.
H04B 10/2531 - Dispositions spécifiques à la transmission par fibres pour réduire ou éliminer la distorsion ou la dispersion due à la dispersion chromatique par inversion spectrale
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Wang, Ningning
Kulkarni, Santosh
O'Mathuna, Cian
Abrégé
The present invention provides a magnetic device for integration on a chip comprising a solenoid comprising multiple windings and a magnetic core comprising a plurality of layers of magnetic material wherein the layers of magnetic material are arranged to form a closed magnetic core.
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
H01F 17/00 - Inductances fixes du type pour signaux
H01F 17/06 - Inductances fixes du type pour signaux avec noyau magnétique avec noyau refermé sur lui-même, p.ex. tore
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Saibal, Roy
Podder, Pranay
Mallick, Dhiman
Amann, Andreas
Abrégé
A vibrational energy harvesting device is disclosed, which comprises first and second assemblies mounted on a base at a distance one from the other. The first assembly comprises vibrational means adapted to stretch under a straining force, whereby the device exhibits monostable quartic nonlinearity. The first and second assemblies comprise respective magnetised means in opposite polarity to one another, so that the second assembly exerts a repulsive magnetic force upon the vibrational means, whereby the device exhibits bistability. Both the monostable quartic and bistable nonlinearities can be independently controlled. A method of harvesting energy with the vibrational energy harvesting device is also disclosed.
H02K 35/02 - Génératrices avec système de bobines, aimant, induit, ou autre partie du circuit magnétique à mouvement alternatif, oscillant ou vibrant avec des aimants mobiles et des systèmes de bobines fixes
64.
AN ETCHING MASK AND A METHOD TO PRODUCE AN ETCHING MASK
The present invention relates to an etching mask comprising silicon containing block copolymers produced by self-assembly techniques onto silicon or graphene substrate. Through the use of the etching mask, nanostructures having long linear features having sub-10 nm width can be produced.
C08L 83/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant dans la chaîne principale de la macromolécule une liaison contenant uniquement du silicium, avec ou sans soufre, azote, oxygène ou carbone; Compositions contenant des dérivés de tels polymères
C09D 153/00 - Compositions de revêtement à base de copolymères séquencés possédant au moins une séquence d'un polymère obtenu par des réactions ne faisant intervenir que des liaisons non saturées carbone-carbone; Compositions de revêtement à base de dérivés de tels polymères
G03F 7/00 - Production par voie photomécanique, p.ex. photolithographique, de surfaces texturées, p.ex. surfaces imprimées; Matériaux à cet effet, p.ex. comportant des photoréserves; Appareillages spécialement adaptés à cet effet
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Smith, Simon Dennis
Henn, Patrick
Gaffney, Robert
Abrégé
The invention provides a wearable venepuncture training device configured for attachment to a limb of a mammal, for example a human, for example an arm, a leg, foot, or hand of a human. The device is generally provided in the form of a sleeve configured for attachment to the limb, and typically comprises a needle -resistant layer, an outer needle-permeable elastic sleeve, and a vasculature layer having at least one artificial blood vessel sandwiched between the needle resistant layer and outer elastic sleeve. Preferably, the device also includes an inner (generally elastic) sleeve that abuts the skin of the wearer, and which is connected to the needle impermeable layer. The vasculature layer comprises a resiliently deformable layer that in use overlies a part of the limb containing vasculature, and comprises at least one elongated groove and at least one artificial blood vessel disposed within the groove in which the groove and vessel mimic a vascular scenario (for example forearm vasculature of a healthy adult, or forearm vasculature of a child). Variation of vasculature will allow simulation of different age related models. The resiliently deformable nature of the vasculature layer mimics the feel of the skin enabling trainee doctors to feel for veins as they would in a real clinical scenario. The outer elastic sleeve helps keep the wearable device in-situ on a limb and ensures that it conforms closely to the limb, again mimicking a real clinical situation. The inner sleeve also ensures that the wearable device remain in-situ on the limb without movement.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Caplice, Noel
Abrégé
Described herein are methods that result in less cell death resulting from myocardial infarction than would otherwise occur in an individual who has suffered myocardial infarction. Also described are compositions useful in reducing cell death post myocardial infarction.
A61L 27/18 - Matériaux macromoléculaires obtenus par des réactions autres que celles faisant intervenir uniquement des liaisons non saturées carbone-carbone
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Riza, Nabeel Agha
Abrégé
The present invention provides a method for performing high dynamic range optical image detection of a scene comprising: imaging incident light from a scene onto an object plane; determining the locations of those pixels in the object plane of higher brightness; detecting the optical irradiance values of those pixels of higher brightness to produce a first detected image; detecting the optical irradiance values of those pixels of lower brightness to produce a second detected image; and generating a high dynamic range optical irradiance map of the scene by combining the first detected image and the second detected image into a single image.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Maaskant, Pleun
Corbett, Brian
Abrégé
The invention relates to a SLED device emitting light from a substrate side, configured to suppress lasing, and comprising a reflective element (55) on a front surface of a substrate (22) configured to redirect an optical beam (light) onto a back surface of the substrate (22). In one embodiment the device can be used for making a compact RGB (red-green-blue) projector.
H01L 33/00 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails
H01L 27/15 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des composants semi-conducteurs avec au moins une barrière de potentiel ou une barrière de surface, spécialement adaptés pour l'émission de lumière
H01L 31/173 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails structurellement associés, p.ex. formés dans ou sur un substrat commun, avec une ou plusieurs sources lumineuses électriques, p.ex. avec des sources lumineuses électroluminescentes, et en outre électriquement ou optiquement couplés avec lesdites sour le dispositif à semi-conducteur sensible au rayonnement étant commandé par la ou les sources lumineuses les sources lumineuses et les dispositifs sensibles au rayonnement étant tous des dispositifs semi-conducteurs caractérisés par au moins une barrière de potentiel ou de surface formés dans, ou sur un substrat commun
H01L 33/46 - Revêtement réfléchissant, p.ex. réflecteur de Bragg en diélectriques
H01L 33/50 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les éléments du boîtier des corps semi-conducteurs Éléments de conversion de la longueur d'onde
H01L 33/58 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les éléments du boîtier des corps semi-conducteurs Éléments de mise en forme du champ optique
H01L 33/60 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les éléments du boîtier des corps semi-conducteurs Éléments de mise en forme du champ optique Éléments réfléchissants
H01S 5/02 - Lasers à semi-conducteurs - Détails ou composants structurels non essentiels au fonctionnement laser
H01S 5/026 - Composants intégrés monolithiques, p.ex. guides d'ondes, photodétecteurs de surveillance ou dispositifs d'attaque
H01S 5/183 - Lasers à émission de surface [lasers SE], p.ex. comportant à la fois des cavités horizontales et verticales comportant uniquement des cavités verticales, p.ex. lasers à émission de surface à cavité verticale [VCSEL]
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Domenico, Pepe
Domenico, Zito
Abrégé
An IQ generator for a vector modulator phase shifter is described. The IQ generator comprises an amplifier (M1, M2, M3, M4) comprising an integrated quadrature coupler (1, 2, 3, 4). The quadrature coupler comprises an input port (1) and an isolated port (4) and a first output port (2) and a second output port (3). The first output port (2) of the quadrature coupler is adapted to generate an in-phase component (VOUT_I) of an output signal of the amplifier and the second output (3) port of the quadrature coupler is adapted to generate a quadrature component (VOUT_Q)of an output signal of the amplifier.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Wang, Ningning
O'Mathuna, Cian
Abrégé
The present invention discloses a centre-tapped transformer. The transformer comprises at least one first layer comprising a first portion of a primary winding interleaved with a first portion of a secondary winding and at least one second layer comprising a second portion of the primary winding interleaved with a second portion of the secondary winding. The second layer is positioned on top of the first layer. The primary winding of the first layer is connected to the primary winding of the second layer through the centre of the first and second layers and the secondary winding of the first layer is connected to the secondary winding of the second layer through the centre of the first and second layers.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Temko, Andriy
Lightbody, Gordon
Marnane, Liam
Boylan, Geraldine
Abrégé
The present invention discloses a method and system of providing a real time audification of neonatal EEG signals. The method comprises the steps of: receiving preprocessed neonatal EEG signals; changing a characteristic of the preprocessed signals in a phase vocoder; resampling the output signals from the vocoder to a predetermined audio frequency range; converting the resampled signals into stereo signals; and selecting a plurality of channels from the stereo signals as the output audio signals.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Kulkarni, Santosh
Wang, Ningning
O'Mathuna, Cian
Abrégé
The invention provides a multi-phase inductor assembly comprising a plurality of coupled inductors, wherein the windings of each inductor are stacked in a vertical arrangement. The invention provides a way to realize stacked coupled inductor for power conversion application, such as Buck converters.
The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or prodrug thereof, and their use in medicine particular as anti-viral agents; wherein: Base is a natural or non-natural nucleobase, and the other substituents are as defined in the claims.
The present invention relates to a method for the treatment of cancer in a subject which comprises the steps of: (i) administering electroporation to a tumour in the subject; and (ii) administering a T or B -cell activating agent to the subject, wherein step (i) and (ii) may be performed in either order.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Murray, Deirdre
Looney, Ann Marie
Boylan, Geraldine
Cryan, John
Abrégé
A method for screening a distressed neonate for risk of having or developing HIE comprises the steps of assaying a biological sample obtained from the distressed neonate, the mother of the neonate, or from the umbilical cord or placenta, for an abundance of miR-374a in the sample, and comparing the abundance of miR-374a in the sample with a reference abundance of miR-374a, wherein a reduced abundance of miR-374a in the sample compared with the reference abundance of miR-374a is indicative of the distressed neonate being at risk of having or developing HIE. Risk of severe HIE can be determined by assaying a biological sample from the distressed neonate identified as being at risk of HIE for an abundance of a plurality of metabolites including succinate, glycerol, acetone and 3-hydroxybutyrate, providing the sum of glycerol and succinate abundance and the sum of acetone and 3-hydroxybutyrate; and correlating the sums with risk of severe HIE.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
76.
THREE DIMENSIONAL LASER BEAM MODULATION-BASED MODULES FOR SENSING, COMMUNICATIONS AND REMOTE ENERGY DELIVERY
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Riza, Nabeel Agha
Abrégé
A high resolution distance sensor comprising a light source (1), a lens (2), a controller (3) and an off-axis imager (4). The off-axis imager provides image acquisition. The sensor is configured for multi-image acquisition of a laser spot size measured away from a minimal axial resolution limit, and measuring a target distance (dt) based on said multi-image acquisition.
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (Irlande)
Inventeur(s)
Ben Larbi, Nadia
Marotta, Mariarosaria
Loscher, Christine
Hickey, Rita Mary
Ryan, Joseph Thomas
Proos, Sinead
Abrégé
This invention provides an oligosaccharide-enriched composition that is derived from a bovine milk whey fraction and comprises at least 30% oligosaccharides (at least 30g per 100g of composition dry weight) having a molecular weight range of 300-1200Da, and at least 20% sialyllactose (at least 20g per 100g of composition dry weight). The oligosaccharide-enriched composition has been found to have a significant immunomodulatory effect (Fig. 1) and has been shown to significantly reduce adhesion of pathogenic bacteria to lung cells and activated pharynx cells, and thereby have a protective effect in humans from respiratory and gastrointestinal infections (Figs 3 and 4). The composition of the invention is derived from a dairy product stream that is substantially free of casein and retains lactose and oligosaccharides, for example demineralised whey powder, demineralised whey, whey permeate, or mother liquor. The dairy product stream is subjected to a micro filtration step to remove whey protein and bacteria, the permeate is then subjected to an ultrafiltration step to enrich for oligosaccharides, and the permeate from the ultrafiltration step is enriched in oligosaccharides having a molecular weight of 300-1200Da, using a chromatographic step.
A23C 9/142 - Préparations à base de lait; Lait en poudre ou préparations à base de lait en poudre dans lesquelles la composition chimique du lait est modifiée par des traitements non chimiques par dialyse, osmose inverse ou ultrafiltration
A23L 1/29 - Modification de la qualité nutritive des aliments; Produits diététiques ( A23L 1/09 a priorité;substituts diététiques du sel A23L 1/22)
A61K 31/702 - Oligosaccharides, c. à. d. ayant trois à cinq radicaux saccharide liés les uns aux autres par des liaisons glycosidiques
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Van Sinderen, Douwe
O'Connell Motherway, Mary
Watson, Debbie
Smokvina, Tamara
Garault, Peggy
Abrégé
The present invention concerns a method; for genetically transforming a. Bifidobacterium strain comprising a step of methylalion of a shuttle sector in. an E. coli or a Gram-positive bacterium strain by two type II DNA methyltransferases from a Bifidobacterium:, a methyltransferase enzyme that methylates the adenine base at position 4 of the nucleotide -sequence RXCAGG and a methyltTansferase enzyme that methylates the cytosine base at position 4 of the nucleotide sequence GGWCC. The present invention also concerns genetic tools and culture media useful for carrying out said method.
Described herein is a non- invasive bacterium that includes a polynucleotide sequence encoding a soluble interferon binding protein that binds to IFN-α, IFN-β, or both, wherein the soluble protein is secretable by the bacterium. The bacterium may be used to aid in the replication of an IFN-sensitive oncolytic virus in a tumorous cancer in a patient.
C07K 14/07 - Virus de la vaccine; Virus de la variole
C07K 16/24 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des cytokines, des lymphokines ou des interférons
C12N 15/47 - Rhabdoviridae, p.ex. virus de la rage, virus de la stomatite vésiculaire
C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteurs; Vecteurs; Utilisation d'hôtes pour ceux-ci; Régulation de l'expression
C12N 7/01 - Virus, p.ex. bactériophages, modifiés par l'introduction de matériel génétique étranger
C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p.ex. glutathion
80.
BILE SALT HYDROLASE BSH1 FOR REGULATING WEIGHT GAIN, SERUM CHOLESTEROL LEVELS, AND LIVER TRIGLYCERIDES IN A MAMMAL; BACTERIA STRAINS EXPRESSING BSH1 VARIANTS
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Joyce, Susan
Gahan, Cormac
Hill, Colin
Abrégé
A non-therapeutic method of reducing weight gain, serum cholesterol levels, or liver triglyceride levels, in a non-obese mammal, comprises the step of administering to the gut of a mammal an effective amount of a bacteria expressing a BSH1 enzyme of SEQUENCE ID NO: 1, or a functional variant thereof; a BSH1 enzyme of SEQUENCE ID NO: 1, or a functional variant thereof for use as a medicament; isolated bacterial strains expressing functional variants of BSH1.
A61K 38/50 - Hydrolases (3) agissant sur des liaisons carbone-azote autres que des liaisons peptidiques (3.5), p.ex. asparaginase
C12N 9/80 - Hydrolases (3.) agissant sur les liaisons carbone-azote autres que les liaisons peptidiques (3.5) agissant sur les liaisons amides des amides aliphatiques
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Duffy, Ray
Shayesteh, Maryam
Huet, Karim
Abrégé
The invention provides a method of forming at least one Metal Germanide contact on a substrate for providing a semiconducting device (100) by providing a first layer (120) of Germanium (Ge) and a second layer of metal. The invention provides a step of reacting the second layer with the first layer with high energy density pulses for obtaining a Germanide metal layer (160A) having a substantially planar interface with the underlying first (Ge) layer.
H01L 21/285 - Dépôt de matériaux conducteurs ou isolants pour les électrodes à partir d'un gaz ou d'une vapeur, p.ex. condensation
H01L 21/268 - Bombardement par des radiations ondulatoires ou corpusculaires par des radiations d'énergie élevée les radiations étant électromagnétiques, p.ex. des rayons laser
82.
ANTIMICROBIAL PEPTIDE PRODUCED BY MARINE SPONGE-DERIVED BACILLUS SUBTILIS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Gara, Fergal
Dobson, Alan
Barbosa, Teresa
Phelan, Robert
Morrissey, John
Abrégé
An isolated lantibiotic peptide obtained from marine sponge-derived B.subtilis strain MMA7, and having potent antibacterial activity against Bacillus cereus and Listeria monocytogenes, is described.
C07K 14/32 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Bacillus (G)
83.
JUNCTIONLESS NANOWIRE TRANSISTORS FOR 3D MONOLITHIC INTEGRATION OF CMOS INVERTERS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Hurley, Paul
Cherkaoui, Karim
Djara, Vladimir
Abrégé
The invention provides a three dimensional (3D) semi-conductor device comprising a first junctionless transistor doped with dopants of the same polarity; a second junctionless transistor doped with dopants of the same polarity; and the second junctionless transistor and the first junctionless transistor comprise an opposite dopant polarity are stacked in a vertical arrangement, where the first and second junctionless transistors are separated by an insulating layer. The invention makes use of the fact that the transistors are uniformly doped with the same polarity to provide a junctionless transistor. The junctionless concept provides that the junction is already formed, so there is no high temperature step associated with junction formation or junction regrowth. This is an important advantage in the junctionless concept in relation to 3D monolithic integration that allows for vertical stacking of the transistors to form a three dimensional CMOS inverter.
H01L 21/8258 - Fabrication ou traitement de dispositifs consistant en une pluralité de composants à l'état solide ou de circuits intégrés formés dans ou sur un substrat commun avec une division ultérieure du substrat en plusieurs dispositifs individuels pour produire des dispositifs, p.ex. des circuits intégrés, consistant chacun en une pluralité de composants le substrat étant un semi-conducteur, en utilisant une combinaison de technologies couvertes par les groupes , , ou
H01L 27/06 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des éléments de circuit passif intégrés avec au moins une barrière de potentiel ou une barrière de surface le substrat étant un corps semi-conducteur comprenant une pluralité de composants individuels dans une configuration non répétitive
H01L 27/092 - Transistors à effet de champ métal-isolant-semi-conducteur complémentaires
H01L 21/8252 - Fabrication ou traitement de dispositifs consistant en une pluralité de composants à l'état solide ou de circuits intégrés formés dans ou sur un substrat commun avec une division ultérieure du substrat en plusieurs dispositifs individuels pour produire des dispositifs, p.ex. des circuits intégrés, consistant chacun en une pluralité de composants le substrat étant un semi-conducteur, en utilisant une technologie III-V
84.
A THORACOSCOPIC ELECTROPORATION DEVICE WITH A SUCTION HEAD AND WITH NEEDLE ELECTRODES
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Soden, Declan
Hinchion, John
Abrégé
A thoracoscopic electroporation device for carrying out electroporation on tissue comprises a suction head (10) and a plurality of needle electrodes. The needle electrodes comprise a central needle (11) providing a first electrode and a plurality of second needles (12, 13, 14, 15, 16, 17) which are spaced-apart around the periphery of the suction head. The second needles are movable from a retracted configuration to a deployed configuration to extend from the suction head. The suction head has a retracted delivery configuration and an expanded deployed configuration. The suction head comprises a suitable flexible material and biasing means (20) for biasing the suction head into the expanded deployed configuration. The suction head has channels (21) for the needles and the needles are movable through the channels from the retracted to the deployed configuration. In the deployed configuration, the central first needle extends beyond the second needles. A vacuum is applied by drawing air out through the central first needle. A therapeutic agent may be applied to the tissue before, during, or after electroporation.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Cantillon-Murphy, Padraig
O'Shea, Conor
O'Riordain, Michael
O'Donoghue, Conor
Burke, Grace
Cummins, Daniel
Finn, Richard
Abrégé
A laparoscopic retractor (11) comprises a shaft (8) having a proximal and distal end, the distal end of the shaft being configured for adjustment from a substantially straight orientation to a curved orientation having a substantially U-shaped hook suitable for laparoscopic retraction. The proximal end of the shaft comprises a handle (1) operably connected to the distal end of the shaft for adjustment of the distal end from the substantially straight orientation to the curved orientation. The distal end of the shaft is enclosed within a flexible sheath (4) that is adapted to be inflated, and wherein a portion of the sheath covering the distal end of the shaft comprises inflatable balloon means such as one or more inflatable balloons (5) which cover the substantially U-shaped hook.
A first aspect of the invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or prodrug thereof, wherein the groups are as defined in the claims. Further aspects of the invention relate to pharmaceutical compositions comprising compounds of formula (I), and the use of compounds of formula (I) in the preparation of a medicament for treating a viral disorder.
C07F 9/6512 - Cycles à six chaînons les atomes d'azote étant en positions 1 et 3
C07F 9/6561 - Composés hétérocycliques, p.ex. contenant du phosphore comme hétéro-atome du cycle contenant des systèmes de plusieurs hétérocycles déterminants condensés entre eux ou condensés avec un carbocycle ou un système carbocyclique commun, avec ou sans autres hétérocycles non condensés
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Gity, Farzan
Corbett, Brian
Morrison, Alan
Hayes, John
Abrégé
In one embodiment the invention relates to a photodetector device sensitive for wavelengths comprising a doped Ge absorbing material bonded to a substrate material locally of opposite doping polarity and an interface layer formed between the Ge absorbing material and the substrate material to form a p-n junction. In one embodiment the bonded material comprises a p-doped Ge wafer and n-doped Si or So I wafer and obtained from a low-temperature heat treatment after bonding. The invention also discloses a process for making a photodetector.
H01L 31/109 - Dispositifs sensibles au rayonnement infrarouge, visible ou ultraviolet caractérisés par une seule barrière de potentiel ou de surface la barrière de potentiel étant du type PN à hétérojonction
H01L 31/18 - Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives
H01L 31/028 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des éléments du groupe IV de la classification périodique
H01L 21/18 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives les dispositifs présentant au moins une barrière de potentiel ou une barrière de surface, p.ex. une jonction PN, une région d'appauvrissement, ou une région de concentration de porteurs de charges les dispositifs ayant des corps semi-conducteurs comprenant des éléments du groupe IV de la classification périodique, ou des composés AIIIBV, avec ou sans impuretés, p.ex. des matériaux de dopage
The present invention provides a non-viral vector which comprises a sequence encoding an RNA replicase and a nuclear localisation sequence. The vector may also comprise a nucleotide sequence of interest (NOI). The vector may be used to deliver an NOI to a target cell.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Stanton, Catherine
Ross, Paul
Fitzgerald, Gerald F.
Caplice, Noel
Shanahan, Fergus
Abrégé
An isolated Lactobacillus mucosae (DPC6426) strain deposited with the National Collection of Industrial and Marine Bacteria Limited (NCIMB) on 27th July 2012 under NCIMB Deposit Accession No. 42015.
The invention provides the discovery and characterization of a novel arterivirus protein (nsp2TF), whose expression is dependent on -2 ribosomal frameshifting at a site located in the nsp2 coding region. The coding region for the unique TF domain of nsp2TF overlaps the part of ORF1a that encodes the transmembrane region of nsp2 in arteriviruses, including PRRSV, LDV and SHFV. Mutations affecting the expression of nsp2TF impair PRRSV replication and result in a smaller plaque phenotype. Provided herein are arteriviruses that display reduced translation of nsp2TF and/or altered translation of one or more downstream products, arteriviruses in which nsp2TF function is reduced and/or absent, and vaccines comprising said arteriviruses. Also provided herein are diagnostic methods, methods for identifying compounds that inhibit -2 frameshifting, and gene expression tools for eukaryotic systems utilizing -2 frameshifting.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND CORK (Irlande)
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND (Irlande)
Inventeur(s)
Morris, Michael
Kerry, Joesph
Cruz, Malco
Cummins, Enda
Abrégé
A package comprising packaging material defining an enclosed space suitable for containing an item susceptible to microbial growth or spoilage is described. An interior of the package comprises at least one antimicrobial surface bearing an ordered nanoarray of metal or metal oxide nanostructures. A packaging material in the form of a sheet or film having a first face and a second face, in which at least a portion of one of the first or second faces of the film comprises a surface bearing a nanoarray of metal or metal oxide nanostructures, is also described.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Quinlan, Jason
Zahran, Ahmed
Sreenan, Cormac
Abrégé
The invention relates to a method and system for scalable description coding for adaptive streaming of data. In particular the invention relates to encoding and/or decoding of video for transmission over packet networks such as the Internet and mobile networks.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Maaskant, Pleun
Corbett, Brian
Henry, Bill
Abrégé
An integrated LED device. The LED device comprises a substrate. The LED device comprises a semiconductor material comprising a light generating layer and positioned on the substrate. The semiconductor material and/or the substrate are configured to control light internally to output quasi-collimated light from a light emitting surface of the LED device. The LED device comprises an optical component positioned at the light emitting surface and configured to receive quasi-collimated light exiting the light emitting surface and to alter one or more optical properties of at least some of the quasi-collimated light.
H01L 33/08 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une pluralité de régions électroluminescentes, p.ex. couche électroluminescente discontinue latéralement ou région photoluminescente intégrée au sein du corps semi-conducteur
H01L 33/20 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué
H01L 33/44 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les revêtements, p.ex. couche de passivation ou revêtement antireflet
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Henry, Bill
Abrégé
An LED chip (30a) for use in an LED chip array forming a continuous array of LEDs. The LED chip (30a) comprises an array of LEDs on a substrate (32a). LEDs in a row of the array are longitudinally offset from corresponding LEDs in another row. Adjacent LEDs in each row of the array are separated by a longitudinal pitch. At least part of an end face (42a) of the substrate (32a) is angled with respect to a transverse axis (40a) of the LED chip (30a) such that the LED chip is positionable adjacent another LED chip (30b) to maintain the longitudinal pitch between adjacent LEDs on different chips.
H01L 33/20 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué
B41J 2/45 - Machines à écrire ou mécanismes d'impression sélective caractérisés par le procédé d'impression ou de marquage pour lequel ils sont conçus caractérisés par l'irradiation sélective d'un matériau d'impression ou de transfert d'impression utilisant des ensembles de sources de rayonnement utilisant des ensembles de diodes émettrices de lumière
H01L 25/075 - Ensembles consistant en une pluralité de dispositifs à semi-conducteurs ou d'autres dispositifs à l'état solide les dispositifs étant tous d'un type prévu dans le même sous-groupe des groupes , ou dans une seule sous-classe de , , p.ex. ensembles de diodes redresseuses les dispositifs n'ayant pas de conteneurs séparés les dispositifs étant d'un type prévu dans le groupe
H01L 27/15 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des composants semi-conducteurs avec au moins une barrière de potentiel ou une barrière de surface, spécialement adaptés pour l'émission de lumière
95.
GABA-PRODUCING CULTURABLE BACTERIA DERIVED FROM THE HUMAN GASTROINTESTINAL TRACT
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Stanton, Catherine
Ross, Paul
Cryan, John
Dinan, Ted
Abrégé
Isolated bacteria are described that are characterised by being culturable, derived from a human neonatal gastrointestinal tract, and having the ability to produce γ-aminobutyric acid. Also described is the use of the GABA-producing bacteria in the treatment or regulation of cardiovascular function, mood disturbance, anxiety, stress, pain and proliferative disorders.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Cantillon-Murphy, Padraig
Cronin, David
Abrégé
The invention provides a kit suitable for performing a surgical procedure that involves a percutaneous incision and placement of a tube within the incision connecting the inside of the body with the outside. Examples of such procedures include a percutaneous endoscopic gastrostomy, percutaneous endoscopic jejunostomy and a sigmoid colostomy. The kit comprises a tube and a first enteral magnet (3) that in use couples with a external magnet (4) across a gastrointestinal (6) and abdominal (5) wall, in which the enteral magnet is located inside the gastrointestinal tract and the external magnet is located externally of the abdomen. The enteral magnet includes a through- hole dimensioned for receipt of the tube, wherein the through-hole of the enteral magnet is capable of aligning with a through-hole of the external magnet upon coupling of the magnets to provide a guide path for passage of the tube.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Morris, Michael
Borah, Dipu
Ghoshal, Tandra
Mokarian, Parvaneh
Abrégé
A method for providing a nanopattern of periodically ordered metal oxide nanostructures on a substrate is described. The method comprises the steps of providing a microphase separated block copolymer as a thin film on a substrate, the block copolymer comprising a first polymer having an affinity for a cations of the metal and a second polymer having a lower affinity for the cations than the first polymer, and selectively incorporating a salt of the metal cation into the first polymer of the block copolymer by means of a solvation process prior to or after formation of the microphase separated block copolymer. The block copolymer film is then treated to oxidise the metal ion salt and remove the polymers leaving a nanopattern of metal oxide nanostructures on the substrate.
G03F 7/00 - Production par voie photomécanique, p.ex. photolithographique, de surfaces texturées, p.ex. surfaces imprimées; Matériaux à cet effet, p.ex. comportant des photoréserves; Appareillages spécialement adaptés à cet effet
B82B 3/00 - Fabrication ou traitement des nanostructures par manipulation d’atomes ou de molécules, ou d’ensembles limités d’atomes ou de molécules un à un comme des unités individuelles
98.
A SINGLE CRYSTAL HIGH DIELECTRIC CONSTANT MATERIAL
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Monaghan, Scott
Povey, Ian
Abrégé
The invention provides a stable oxide material system for a capacitor, electronic device or a memory device having an effective high-k value with an effective zero alpha while exhibiting low leakage current density. The stable oxide material comprises MxSi1-xO2, wherin the elements M & Si are mixed such that the insulator layer comprises staggered edge-linked S iO2-MO2 bonding chains to provide a stable 3-dimensional single crystal system.
C23C 16/455 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c. à d. procédés de dépôt chimique en phase vapeur (CVD) caractérisé par le procédé de revêtement caractérisé par le procédé utilisé pour introduire des gaz dans la chambre de réaction ou pour modifier les écoulements de gaz dans la chambre de réaction
H01L 21/02 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives
H01L 21/28 - Fabrication des électrodes sur les corps semi-conducteurs par emploi de procédés ou d'appareils non couverts par les groupes
H01L 29/51 - Matériaux isolants associés à ces électrodes
An integrated dual-axis anisotropic magnetoresistive sensor can include a first sensor unit and a second sensor unit. The first sensor unit can have a resistor bridge including a plurality of magnetoresistors, each having at least one elongated strip of anisotropic magnetoresistive material having a longitudinal axis substantially parallel to a technological anisotropy axis of the magnetoresistive material. The second sensor unit can have a resistor bridge including a plurality of magnetoresistors having a plurality of elongated strips of anisotropic magnetoresistive material, wherein the plurality of strips includes a first subset of strips having longitudinal axes aligned at a first angle to the technological anisotropy axis and a second subset of strips having longitudinal axes aligned at a second angle to the technological anisotropy axis.
G01R 33/09 - Mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques en utilisant des dispositifs galvano-magnétiques des dispositifs magnéto-résistifs
100.
ACCUMULATION OF METABOLIC PRODUCTS IN BACTERIAL MICROCOMPARTMENTS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
UNIVERSITY OF KENT (Royaume‑Uni)
Inventeur(s)
Prentice, Michael
Warren, Martin
Liang, Mingzhi
Abrégé
A non-therapeutic method of accumulating a polymeric or high molecular weight molecular product within a bacterial microcompartment in bacterial cytoplasm, which method employs a recombinant bacteria which is transformed to express a microcompartment containing an enzyme capable of converting a low molecular weight substrate into a polymeric or high molecular weight product, the method comprising the steps of: incubating the recombinant bacteria with the low-molecular weight substrate, or a precursor of the low molecular weight substrate which is capable of being metabolised to the substrate within the recombinant bacteria, such that the substrate or precursor is taken up by the bacteria, wherein the substrate enters the microcompartment and the enzyme within the microcompartment converts the substrate to a polymeric or high molecular weight molecular product, and wherein the polymeric or high molecular weight molecular product is accumulated within the microcompartment due to its size.