UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Arendt, Elke
Abrégé
A method of processing spent brewer's yeast (BSY) to a fermented BSY product is described. The BSY product is a pleasant tasting, nutritious and functional ingredient which enables the ingredient to be used for human consumption in foods and beverages. The method comprises autolysis of the BSY followed by lactic acid fermentation and optionally drying. The method reduces the bitterness drastically, removes RNA and alcohol significantly, and changes the sensory profile as well as the techno-functional properties of the fermented BSY. The resultant fermented BSY product is very high in protein and valuable dietary fibre and therefore follows the current trend to increase the intake of plant and mycoproteins and fibre.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Moore, Tom
Abrégé
The use of Fc-tagged Pregnancy-specific glycoprotein 1 (PSG1-Fc) in a method of treatment of a tendon injury in a human, in which the PSG1 is administered by intra-tendon or peri-tendon injection, is described. Also described is the use of CC49 in a method of treatment of tendonitis, tendinosis, tendinopathy, or tendon damage in an equine mammal, in which the CC49 is administered by intra-tendon or peri-tendon injection.
University College Cork - National University of Ireland, Cork (Irlande)
Agriculture and Food Development Authority (TEAGASC) (Irlande)
Inventeur(s)
Caplice, Noel
Stanton, Catherine
Ross, Paul
Herisson, Florence
Karnik, Kavita
De Souza, Mervyn
Laurie, Ieva
Canene-Adams, Kirstie
Abrégé
The present disclosure provides compositions comprising Lactobacillus mucosae and soluble dietary fiber, and methods treatment related thereto, useful against metabolic syndrome and related diseases, disorders and morbidities.
A61K 35/747 - Lactobacilles, p.ex. L. acidophilus ou L. brevis
A61K 47/36 - Polysaccharides; Leurs dérivés, p.ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p.ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/04 - Anorexigènes; Médicaments de l'obésité
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
4.
BIOMARKERS PREDICTIVE OF ATOPIC DERMATITIS IN INFANTS AND THEIR USE TO FACILITATE PREVENTION AND/OR TREATMENT OF ATOPIC DERMATITIS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND (Irlande)
Inventeur(s)
Stamatas, Georgios N.
Sato, Takahiro
Oddos, Thierry
Hourihane, Jonathan
Irvine, Alan D.
Insel, Richard A.
Abrégé
A method to predict a propensity of an infant to develop atopic dermatitis. The method includes observing the expression of S100A8/A9 on a skin area of an infant; comparing the expression to determined standard, wherein the determined standard is ascertained by measuring a level of the biomarker in a subject or pool of subjects who have demonstrated an absence of atopic dermatitis; and determining the propensity of an infant to develop atopic dermatitis, wherein an increase in the expression as compared to the determined standard indicates propensity of the infant to develop atopic dermatitis.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
5.
Biomarkers Predictive of Atopic Dermatitis that Facilitate Prevention and/or Treatment of the Onset Atopic Dermatitis
University College Cork – National University of Ireland (Irlande)
Inventeur(s)
Stamatas, Georgios
Oddos, Thierry
Sato, Takahiro
Hourihane, Jonathan
Irvine, Alan D.
Insel, Richard A.
Abrégé
A method to predict a propensity of an infant to develop atopic dermatitis. The method includes observing the expression of S100A8/A9 on a skin area of an infant; comparing the expression to determined standard, wherein the determined standard is ascertained by measuring a level of the biomarker in a subject or pool of subjects who have demonstrated an absence of atopic dermatitis; and determining the propensity of an infant to develop atopic dermatitis, wherein an increase in the expression as compared to the determined standard indicates propensity of the infant to develop atopic dermatitis.
C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Software; software for use in monitoring apparatus; software for use in medical apparatus; software for use in instruments for monitoring a foetus. Medical apparatus and instruments for use in the measuring and monitoring of human body reactions in metric units; and medical apparatus and instruments for use in measuring and monitoring heart beats; Medical apparatus and instruments; monitoring apparatus and instruments for medical purposes; heart monitors; foetal monitoring apparatus; instruments for monitoring a foetus; foetal heart monitors; foetal heart rate monitors; instruments for monitoring the heart of a foetus; foetal heart activity recorders; foetal heart rate recorders; electronic foetal heart signal monitors; electronic instruments for monitoring the heart signal of a foetus; electronic foetal heart signal recorders; instruments for observing foetal heart activity; instruments for recording foetal heart activity; foetal electrocardiographic monitors; foetal electrocardiographic instruments; foetal electrocardiographic recorders; foetal activity monitors; instruments for monitoring physical activity of a foetus; maternal heart monitors; maternal heart rate monitors; instruments for monitoring the heart of a pregnant woman; maternal heart activity recorders; maternal heart rate recorders; electronic maternal heart signal monitors; electronic instruments for monitoring the heart signal of a pregnant woman; electronic maternal heart signal recorders; maternal activity monitors; instruments for monitoring physical activity of a pregnant woman; maternal temperature monitors; instruments for monitoring the temperature of a pregnant woman; instruments for monitoring the uterine activity of a pregnant woman; instruments for recording the uterine activity of a pregnant woman; instruments for capturing the morphological nature of electrocardiographic complexes on different parts of a pregnant woman's abdomen; instruments for recording the morphological nature of electrocardiographic complexes on different parts of a pregnant woman's abdomen; medical electrodes; electrophysiology electrodes; electrodes for use with foetal monitoring apparatus; consumable electrodes for use with foetal monitoring apparatus; electrodes for use with foetal electrocardiographic monitors; cutaneous electrodes for medical use; devices for securing medical electrodes to the skin of a patient; devices for securing cutaneous electrodes to the skin of a patient; apparatus for medical image formation; apparatus for foetal image formation; apparatus for foetal heart image formation; apparatus for emulating electrophysiological signals from a pregnant woman; apparatus for emulating foetal electrocardiographic signals. Scientific and technological research services; medical and scientific research.
University College Cork - National University of Ireland,Cork (Irlande)
Inventeur(s)
Corbett, Brian
Roycroft, Brendan
Abrégé
An optical power converter device (200, 300) comprises a semiconductor waveguide structure having a first end facet (F1) configured to receive an incident light beam, and one or more light absorbing layers (210a) with a total thickness of substantially less than 100 nm and configured to absorb light guided by the waveguide structure. The device further comprises a cathode (202) and an anode (204) in contact with substantially the entire length of the waveguide structure in the direction of propagation of light from the first end facet for outputting generated electrical power. An optical power converting system (1000) comprising the optical power converter device is also provided, as is a method of operating the optical power converter.
H01L 31/054 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] Éléments optiques directement associés ou intégrés à la cellule PV, p.ex. moyens réflecteurs ou concentrateurs de lumière
H01L 31/072 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type PN à hétérojonction
8.
WINDOW OF OPPORTUNITY SKIN TREATMENT REGIMEN AND COMPOSITION FOR PREVENTING THE ONSET OF OR TREATING ATOPIC DERMATITIS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Ouyang, Xing
Townsend, Paul
Abrégé
A method of estimating channel state information (CSI) of a Multiple Input Multiple Output (MIMO) channel includes transmitting pilot symbols from a plurality of transmission antennas, wherein a number of pilot symbols are transmitted using chirped signals based on the Fresnel transform for generating Orthogonal chirp-division multiplexing (OCDM) signals, the number of pilot symbols overlap in time-domain, a single symbol interval is utilized to estimate a transfer matrix of the MIMO channel, and no silent pilot symbols are transmitted.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Zubialevich, Vitaly Z.
Parbrook, Peter J.
Pampili, Pietro
Abrégé
A semiconductor heterostructure device for use as a component in an optoelectronic component, the device has a substrate, a nanocolumn extending from the substrate, a self-centred passivation layer on top of the nanocolumn, an active region which comprises a quantum well (QW) stack on a vertical side of the nanocolumn and wherein the passivation layer extends horizontally outwards from the nanocolumn to overhang the nanocolumn and the QW stack. The device provides for efficient NC heterostructure based light emitting diodes (LEDs) and other optoelectronic devices with an active region located purely on non-polar facets of the NCs. It also eliminates parasitic current paths allowing core-shell nanorod-based LEDs with emission from the desired facets only.
H01L 33/24 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué de la région électroluminescente, p.ex. jonction du type non planaire
H01L 33/06 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure à effet quantique ou un superréseau, p.ex. jonction tunnel au sein de la région électroluminescente, p.ex. structure de confinement quantique ou barrière tunnel
H01L 33/18 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure cristalline ou une orientation particulière, p.ex. polycristalline, amorphe ou poreuse au sein de la région électroluminescente
H01L 33/32 - Matériaux de la région électroluminescente contenant uniquement des éléments du groupe III et du groupe V de la classification périodique contenant de l'azote
H01L 33/44 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les revêtements, p.ex. couche de passivation ou revêtement antireflet
The present invention provides a fetal monitoring device and method, and in particular a real time fetal pH, lactate and physiological monitoring device for detection and prevention of perinatal hypoxia, the device including an optical sensor operable to emit light at a wavelength of between 1050nm-3000nm onto vascularised tissue on the fetal scalp and to detect the reflected light, in addition to a processor operable to convert real time spectroscopy data from the reflected light into correlated real time data regarding one or more biological markers.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale
A61B 5/1464 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale spécialement adaptés pour des tissus fœtaux
A61B 5/01 - Mesure de la température de parties du corps
A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Pavlovic, Zoran
O'Driscoll, Séamus
Abrégé
A device (90) is disclosed, comprising: a first upper conducting layer (101) and second upper conducting layer (102); a first lower conducting layer (111) and second lower conducting layer (112); a core layer (131) between the first and second upper conducting layers (101, 102) and the first and second lower conducting layers (111, 112); a first via (121) connecting the first upper conducting layer (101) to the first lower conducting layer (111); a second via (122) connecting the second upper conducting layer (102) to the second lower conducting layer (112). The first via (121) and the second via (122) are concentric.
H01F 17/00 - Inductances fixes du type pour signaux
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
14.
POLYPEPTIDES CAPABLE OF LIMITING THE REPLICATION OF A CORONAVIRUS
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (Canada)
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (Canada)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Pelletier, Gerard
Girgis, Samer
Ragoussis, Ioannis
Oikonomopoulos, Spyridon
Vidal, Silvia
Malo, Danielle
Hobman, Tom
Xu, Zaikun
Baranov, Pavel
Fedorova, Alla
Abrégé
The present invention relates to polypeptides capable of limiting the replication of coronavirus and/ or nucleic acid molecules encoding polypeptides capable of limiting the replication of coronavirus, including those comprising a Nsp1-10 fusion and/or Nsp12. The present invention also relates to methods of using said polypeptides and/or nucleic acid molecules encoding said polypeptides for the treatment coronavirus infections in a subject in need thereof.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
LOUGHBOROUGH UNIVERSITY (Royaume‑Uni)
Inventeur(s)
Zargana, Karsan
Fernandez-Mato, Antonio
Holmes, Justin
Abrégé
A method of recycling a plastic product comprising PET is provided. The method comprises combining a plastic product comprising PET, a heterogeneous metal oxide catalyst and a solvent to provide a reaction mixture and heating the mixture by microwave irradiation to provide reaction product.
C08J 11/16 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p.ex. dévulcanisation par traitement avec une substance inorganique
C08J 11/24 - Récupération ou traitement des résidus des polymères par coupure des chaînes moléculaires des polymères ou rupture des liaisons de réticulation par voie chimique, p.ex. dévulcanisation par traitement avec une substance organique par traitement avec des composés organiques contenant de l'oxygène contenant des groupes hydroxyle
University College Cork - National University of Ireland, Cork (Irlande)
Inventeur(s)
O’toole, Paul
Jeffery, Ian
Ghosh, Tarini
Tan, Huizi
Perez, Marta
Ntemiri, Alexandra
Abrégé
A probiotic composition is provided comprising at least two isolated bacterial species or comprising a purified bacterial preparation comprising at least two bacterial species, wherein the at least two bacterial species are selected from the group consisting of Coprococcus catus, Eubacterium rectale, Alistipes putredinis, Barnesiella intestinihominis, Roseburia hominis, Dorea longicatena and Faecalibacterium prausnitzii. Also provided are specific isolated bacterial strains and use of the composition for treating frailty and/or inflammation related to aging in elderly subjects.
University College Cork, National University of Ireland, Cork (Irlande)
Inventeur(s)
O'Brien, Peter
Abrégé
A photonic integrated circuit (PIC) assembly that includes a PIC, and a light source mounted on a first carrier substrate, and optically coupled and aligned with the PIC. The first carrier substrate includes a wrap-around metal, that enables the first carrier substrate to be bonded electrically with the PIC using solder bumps, and wherein the wrap-around metal enables the first carrier substrate to be electrically controlled by an external device for facilitating alignment and optical coupling process with the PIC.
University College Cork - National University of Ireland, Cork (Irlande)
Inventeur(s)
O'Brien, Peter
Abrégé
The present disclosure is directed towards aligning a photonic integrated circuit (PIC) through providing a PIC with a marker waveguide, wherein a marker waveguide is a waveguide having: a first end located at the edge of the PIC wherein the first end is coupled to an edge coupling; and a second end coupled to a grating coupler or a device coupler, wherein: the grating coupler or device coupler is configured to receive light and couple the light to the waveguide to illuminate the waveguide to facilitate the correct alignment of the edge coupler to an external component.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Mokarian-Tabari, Parvaneh
Morris, Michael
Senthamaraikannan, Ramsankar
Abrégé
The invention provides a solution based process based on high molecular weight block copolymer (BCP) nanolithography for fabrication of periodic structures on large areas of optical surfaces. In one embodiment there is provided method of fabricating a nano-patterned surface for application in a photonic, optical or other related device, said method comprising the steps of: providing a substrate material; depositing a block copolymer (BCP) material on the substrate material; and phase separating the BCPs using at least one solvent selected to facilitate polymer chain mobilisation and lead to phase separation to fabricate said nano-patterned surface; wherein the nano-patterned surface comprises an ordered array of structures and having a domain or diameter of 100 nm or greater. A new photonic device and optical device is also described.
H01L 33/20 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué
21.
AN OPTICAL FIBER CATHETER PROBE AND A MANUFACTURING METHOD THEREOF
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Brien, Peter
Abrégé
The catheter probe comprises a catheter tip and a catheter body. The catheter tip comprises a plurality of channels for housing a plurality of optical sensors. Each one of said plurality of optical sensors comprises a ferrule comprising a via, a microlens aligned with said via and attached to said ferrule and an optical fiber for optically coupling said microlens to a monitoring means.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
22.
TREATMENT OF CEREBROVASCULAR EVENTS AND NEUROLOGICAL DISORDERS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND CORK (Irlande)
Inventeur(s)
Moore, Tom
Waeber, Christian
Abrégé
The invention provides a Pregnancy-specific glycoprotein (for example PSG1) for use in a method of treating neurological disorders or stimulating survival or recovery of tissue damaged by a cerebrovascular event or brain trauma in a subject. The PSG1 may be Fc-tagged PSG1.
A61K 38/17 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p.ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénal
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
23.
TREATMENT OF CEREBROVASCULAR EVENTS AND NEUROLOGICAL DISORDERS
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Moore, Tom
Waeber, Christian
Abrégé
The invention provides a Pregnancy-specific glycoprotein (for example PSG1) for use in a method of treating neurological disorders or stimulating survival or recovery of tissue damaged by a cerebrovascular event or brain trauma in a subject. The PSG1 may be Fc-tagged PSG1.
A61K 38/17 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains
A61P 9/10 - Médicaments pour le traitement des troubles du système cardiovasculaire des maladies ischémiques ou athéroscléreuses, p.ex. médicaments antiangineux, vasodilatateurs coronariens, médicaments pour le traitement de l'infarctus du myocarde, de la rétinopathie, de l'insuffisance cérébro-vasculaire, de l'artériosclérose rénal
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Moore, Tom
Clover, Anthony James Peterson
Abrégé
The use of Fc-tagged Pregnancy-specific glycoprotein 1 (PSG1-Fc) in a method of treatment of osteoarthritis or damaged cartilage in a human, in which the PSG1 is administered by intra-articular injection, is described. Also described is the use of CC49 in a method of treatment of osteoarthritis or damaged cartilage in an equine mammal, in which the CC49 is administered by intra-articular injection. (Fig. 3A-C) Also described is the use of PSG1 in a method of treatment of wounds, scarring, burns and diabetic ulcers in a mammal.
A61K 38/17 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p.ex. arthrites, arthroses
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Moore, Tom
Clover, Anthony James Peterson
Abrégé
The use of Fc-tagged Pregnancy-specific glycoprotein 1 (PSG1-Fc) in a method of treatment of osteoarthritis or damaged cartilage in a human, in which the PSG1 is administered by intra-articular injection, is described. Also described is the use of CC49 in a method of treatment of osteoarthritis or damaged cartilage in an equine mammal, in which the CC49 is administered by intra-articular injection. (Fig. 3A-C) Also described is the use of PSG1 in a method of treatment of wounds, scarring, burns and diabetic ulcers in a mammal.
A61K 38/17 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p.ex. arthrites, arthroses
26.
LACTICASEIBACILLUS PARACASEI EM025-11 AND USES THEREOF
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
TEAGASC - THE AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (Irlande)
Inventeur(s)
O'Toole, Paul
Van Sinderen, Douwe
Ross, Paul
Melgar, Silvia
Abrégé
A strain of Lacticaseibacillus paracasei EM025-11 is described. The strain has an unusually broad catabolic activity including for prebiotics not normally utilized by commensal lactobacilli and is therefore suitable for inclusion in a synbiotic combination. The strain has also been found to adhere to but did not invade intestinal epithelial cells (IECs), which is an important probiotic trait (Fig. 1), and also demonstrates anti-inflammatory activity.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Caplice, Noel
Stanton, Catherine
Ross, Paul
Herisson, Florence
Karnik, Kavita
De Souza, Mervyn
Laurie, Ieva
Canene-Adams, Kirstie
Abrégé
The present disclosure provides compositions comprising Lactobacillus mucosae and soluble dietary fiber, and methods treatment related thereto, useful against metabolic syndrome and related diseases, disorders and morbidities.
A23L 29/269 - Aliments ou produits alimentaires contenant des additifs; Leur préparation ou leur traitement contenant des agents gélifiants ou épaississants d'origine microbienne, p.ex. xanthane ou dextrane
A61K 35/747 - Lactobacilles, p.ex. L. acidophilus ou L. brevis
A23L 33/135 - Bactéries ou leurs dérivés, p.ex. probiotiques
A23L 33/21 - Adjonction de substances essentiellement non digestibles, p.ex. de fibres diététiques
29.
METHODS AND COMPOSITIONS USING COMBINATIONS OF LACTOBACILLUS MUCOSAE AND SOLUBLE DIETARY FIBER
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Caplice, Noel
Stanton, Catherine
Ross, Paul
Herisson, Florence
Karnik, Kavita
De Souza, Mervyn
Laurie, Ieva
Canene-Adams, Kirstie
Abrégé
Lactobacillus Lactobacillus mucosae and soluble dietary fiber, and methods treatment related thereto, useful against metabolic syndrome and related diseases, disorders and morbidities.
A23L 29/269 - Aliments ou produits alimentaires contenant des additifs; Leur préparation ou leur traitement contenant des agents gélifiants ou épaississants d'origine microbienne, p.ex. xanthane ou dextrane
A23L 33/135 - Bactéries ou leurs dérivés, p.ex. probiotiques
A23L 33/21 - Adjonction de substances essentiellement non digestibles, p.ex. de fibres diététiques
A61K 35/747 - Lactobacilles, p.ex. L. acidophilus ou L. brevis
30.
MICRONEEDLES, AND METHODS FOR THE MANUFACTURE THEREOF
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Faisal, Waleed
Crean, Abina
Abrégé
A microneedle with very high drug loading is described, and comprises a base and a penetrating tip, the tip having a dimension ranging from about 50 nm to about 50 μm, wherein at least 80% of the microneedle by volume consists of heat-meltable active pharmaceutical ingredient (v/v). The meltable active pharmaceutical ingredient is characterised by being heat-meltable (i.e. it can be heated to a molten form), is solid at 25° C., and has an ability to form a glassy, amorphous form following melting by heating and cooling with a glass transition temperature greater than 25° C. A method of fabricating a microneedle comprises the steps of providing a microneedle micromold comprising a micromold substrate and one or more holes in the upper surface of the micromold substrate, wherein the interior surface of the hole in the micromold substrate defines an exterior surface of the microneedle, moulding a meltable drug in the microneedle micromold to form a microneedle, and separating the microneedle from the microneedle micromold. Microneedles of the invention may incorporate up to 99% drug or more.
A61M 37/00 - Autres appareils pour introduire des agents dans le corps; Percutanisation, c. à d. introduction de médicaments dans le corps par diffusion à travers la peau
A61K 31/196 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe amino le groupe amino étant lié directement à un cycle, p.ex. acide anthranilique, acide méfénamique, diclofénac, chlorambucil
A61K 31/192 - Acides carboxyliques, p.ex. acide valproïque ayant des groupes aromatiques, p.ex. sulindac, acides 2-aryl-propioniques, acide éthacrynique
A61K 31/519 - Pyrimidines; Pyrimidines hydrogénées, p.ex. triméthoprime condensées en ortho ou en péri avec des hétérocycles
University College Cork - National University of Ireland, Cork (Irlande)
Inventeur(s)
Ross, Paul
Stanton, Catherine
Abrégé
A composition for use in a method of regulating or treating a metabolic disease or a symptom thereof, the composition comprising an isolated bacteria Lactobacillus brevis (DPC6108) deposited with the National Collection of Industrial and Marine Bacteria Limited (NCIMB) on 28 Nov. 2011 and accorded the accession number NCIMB 41903.
University College Cork—National University of Ireland, Cork (Irlande)
Inventeur(s)
Riza, Nabeel Agha
Abrégé
The present invention provides a method for performing optical image detection using a camera module comprising a Digital MicroMirror Device, a first point Photo Detector, a second point Photo Detector, a first lens and a second lens. The method comprises: mapping incident light onto an image plane of the DMD to form a light irradiance map; selecting N pixels on the DMD for time frequency coding; associating each selected pixel with a unique Walsh code time sequence; time frequency coding by the DMD the optical irradiance values of each selected pixel using a plurality of selected bits of its associated Walsh code time sequence; detecting the time frequency coded optical irradiance values of the selected pixels simultaneously at the first point Photo Detector and at the second point Photo Detector; and performing simultaneous signal processing on the time frequency coded optical irradiance values detected by the first point Photo Detector and by the second point Photo Detector to determine the light intensity of each of the selected pixels and produce an image of the incident light.
G02B 26/08 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander la direction de la lumière
G02B 27/10 - Systèmes divisant ou combinant des faisceaux
G02B 27/14 - Systèmes divisant ou combinant des faisceaux fonctionnant uniquement par réflexion
H03M 7/30 - Compression; Expansion; Elimination de données inutiles, p.ex. réduction de redondance
H04N 23/741 - Circuits de compensation de la variation de luminosité dans la scène en augmentant la plage dynamique de l'image par rapport à la plage dynamique des capteurs d'image électroniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Software as a medical device (SaMD), downloadable for electroencephalograph (EEG) monitoring and decision support in neonatal care and neurology; Downloadable computer software relating to the medical field for electroencephalograph (EEG) data analysis, storage, display, and diagnostic decision support; Downloadable software using artificial intelligence for diagnostic decision support in neonatal care and neurology; Downloadable software using artificial intelligence for analysis of electroencephalograph (EEG) data; Downloadable software using artificial intelligence for healthcare purposes, namely, neonatal and neurology care; Downloadable interactive software using artificial intelligence for electroencephalograph (EEG) monitoring; Wireless controllers to remotely monitor and control the function and status of other electrical, electronic, and mechanical devices or systems; Downloadable health monitoring software for monitoring electroencephalograph (EEG) data; Downloadable computer software for remote monitoring and analysis of electroencephalograph (EEG) data Medical devices, namely, electroencephalograph (EEG) monitors; Measuring devices for medical use, namely, devices for measuring electroencephalograph (EEG) data; Medical diagnostic instruments for analysis of electroencephalograph (EEG) data; Medical analysis instruments, namely, electroencephalograph (EEG) monitors for analyzing brain function; Medical testing instruments for testing brain function; Electronic medical instruments for electroencephalograph (EEG) monitoring; Diagnostic instruments for medical use, namely, electroencephalograph (EEG) monitors for abnormal brain function; Detecting instruments for medical use for detecting abnormal brain function; Medical apparatus and instruments for electroencephalograph (EEG) monitoring; Medical instruments, namely, electroencephalograph (EEG) monitors for recording physiological data; Instruments for use in medical analysis, namely, electroencephalograph (EEG) monitoring; Electronic monitoring instruments for medical use, namely, electroencephalograph (EEG) monitors for monitoring brain function; Testing instruments for medical diagnostic purposes, namely, electroencephalograph (EEG) monitors for diagnosing abnormal brain function; Medical instruments for application on human bodies, namely, electroencephalograph (EEG) monitors for monitoring brain function; Physiological monitoring apparatus for medical use, namely, electroencephalograph (EEG) monitors for monitoring brain function; Sensor apparatus for medical use in monitoring the vital signs of patients; Wearable monitors used to measure biometric data for medical use Design and development of computer software for use with medical technology; Software as a service (SaaS) services featuring software using artificial intelligence for electroencephalograph (EEG) monitoring and diagnostic decision support; Platforms as a service (PaaS) services featuring computer software platforms using artificial intelligence for electroencephalograph (EEG) monitoring and diagnostic decision support; Scientific research; Scientific research services for others in the field of electroencephalograph (EEG) monitoring; Scientific research and analysis in the field of electroencephalograph (EEG) monitoring; Scientific research and development; Scientific research for medical purposes in the fields of electroencephalograph (EEG) monitoring; Computer aided scientific research services for others in the field of electroencephalograph (EEG) monitoring; Scientific services and research relating thereto, namely, electroencephalograph (EEG) monitoring; Advisory services relating to scientific research
34.
TUMOR SENSOR SYSTEM FOR TUMOR LOCALIZATION, THERAPY RESPONSE, AND IMAGE GUIDED SURGERY
STICHTING HET NEDERLANDS KANKER INSTITUUT - ANTONI VAN LEEUWENHOEK ZIEKENHUIS (Pays‑Bas)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Ruers, Theodoor Jacques Marie
Burke, Ray
Abrégé
A tumor sensor system comprising an implantable probe and an auxiliary device, the probe comprising at least one sensor configured to generate an electric signal in response to a physical stimulus, wherein the at least one sensor comprises a position sensor configured to sense a signal from a position tracking system wherein the sensed signal is indicative of a position of the probe in a space, wherein the position sensor comprises at least one electromagnetic sensor configured to cooperate with an external electromagnetic field generator, wherein the at least one electromagnetic sensor is configured to detect a property of the electromagnetic field and send it as an electric signal to the processing circuit, at least one antenna for data communication by means of inductive communication, an energy harvesting coil, and transmitting the data via the at least one antenna to the auxiliary device.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Sullivan, Mark
Temko, Andriy
O'Shea, Alison
Boylan, Geraldine
Popovici, Emanuel
Abrégé
The present invention relates to an integrated system and method for EEG signal acquisition and interpretation, for neonatal seizure detection. The system as per the present invention comprises a control device, an integrated circuit, a wireless communication module, a visual indication means, and a power management module. The control device has a Convolutional Neural Network (CNN) embedded on it, and is programmed to configure the integrated circuit to receive a plurality of channels of EEG data from a plurality of EEG acquisition electrodes, and to amplify and digitize the received EEG data. The integrated circuit is further configured to segment the channels of EEG data to a plurality of sequential epochs of EEG data. The control device is configured to pass the sequential epochs of EEG data through the CNN which is pre-trained to output the probability of a seizure in the EEG data passed through it. The channels of EEG data received from the acquisition electrodes and the probability of seizure outputted by the CNN is communicated to at least remote computing device by the communication module. A filter is applied to smooth the outputs in a post-processing routine. The visual indication means is enabled if the output of the CNN exceeds a predetermined threshold probability.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
TEAGASC, THE AGRICUL TURE AND FOOD DEVELOPMENT AUTHORITY (Irlande)
Inventeur(s)
Ross, Reynolds Paul
Stanton, Catherine
Hill, Colin
Ryan, Anthony
O'Sullivan, Julie
Watkins, Claire
Abrégé
An isolated lantibiotic is provided comprising amino acid sequence SEQ. ID No. 2 and at least one of amino acid sequences SEQ. ID No. 4 and SEQ. ID. No 6. Also provided is use of the lantibiotic in the treatment or prevention of infection by Group B Streptococcus or Corynebacterium xerosis. The invention further relates to isolated S. hominis strains and use of same in producing the lantibiotic. A vector is provided comprising nucleotides sequences for producing the lantibiotic.
C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p.ex. Lactobacillus, Micromonospora
C07K 14/31 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Micrococcaceae (F) provenant de Staphylococcus (G)
05 - Produits pharmaceutiques, vétérinaires et hygièniques
41 - Éducation, divertissements, activités sportives et culturelles
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Dietetic and nutritional supplements for pre-term infants Educational services, namely, providing training in the field of nutrition and diet for pre-term infants Providing dietary and nutritional advice in relation to pre-term infants
38.
TREATMENT OR PREVENTION OF HEPATIC METABOLIC CONDITIONS ASSOCIATED WITH DIABETES
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
UNIVERSITY COLLEGE DUBLIN (Irlande)
Inventeur(s)
Roche, Helen
O'Toole, Paul
Mitchelson, Kathleen
Tram, Tam
Vlckova, Klara
Abrégé
A whole (1→3)-β-D-glucan particle for treating or preventing a hepatic metabolic condition associated with obesity or diabetes in a subject is provided. The method comprises administering an effective amount of a whole (1→3)-β-D-glucan particle to said subject. The glucan is β-1,6 branched β-1,3 glucan.
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p.ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p.ex. antidiabétiques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Software as a medical device [SaMD], downloadable; Computer software relating to the medical field; Artificial intelligence software; Artificial intelligence software for analysis; Artificial intelligence software for healthcare; Interactive software based on artificial intelligence; Wireless controllers to remotely monitor and control the function and status of other electrical, electronic, and mechanical devices or systems; Health monitoring software; Downloadable computer software for remote monitoring and analysis; Computer software for use in remote meter monitoring. Medical devices; Measuring devices for medical use; Medical diagnostic instruments; Medical analysis instruments; Medical testing instruments; Electronic medical instruments; Diagnostic instruments for medical use; Detecting instruments for medical use; Medical apparatus and instruments; Medical instruments for reproducing physiological data; Scanning machines for medical use; Scanning instruments for medical use; Medical instruments for recording physiological data; Instruments for use in medical analysis; Electronic monitoring instruments for medical use; Testing instruments for medical diagnostic purposes; Medical instruments for application on human bodies; Medical instruments for application in human bodies; Physiological monitoring apparatus for medical use; Sensor apparatus for medical use in monitoring the vital signs of patients; Wearable monitors used to measure biometric data for medical use. Design and development of computer software for use with medical technology; Platforms for artificial intelligence as software as a service [SaaS]; Software as a service [SaaS] featuring computer software platforms for artificial intelligence; Scientific research; Scientific research services; Scientific research and analysis; Scientific research and development; Scientific research for medical purposes; Computer aided scientific research services; Scientific services and research relating thereto; Advisory services relating to scientific research.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY IRELAND, CORK (Irlande)
Inventeur(s)
Corbett, Brian
Roycroft, Brendan
Abrégé
An optical power converter device (200, 300) comprises a semiconductor waveguide structure having a first end facet (F1) configured to receive an incident light beam, and one or more light absorbing layers (210a) with a total thickness of substantially less than 100 nm and configured to absorb light guided by the waveguide structure. The device further comprises a cathode (202) and an anode (204) in contact with substantially the entire length of the waveguide structure in the direction of propagation of light from the first end facet for outputting generated electrical power. An optical power converting system (1000) comprising the optical power converter device is also provided, as is a method of operating the optical power converter.
H01L 31/0232 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails - Détails Éléments ou dispositions optiques associés au dispositif
G02B 6/122 - Elements optiques de base, p.ex. voies de guidage de la lumière
H01L 31/0304 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIIIBV
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
41.
A METHOD OF PREDICTING THE RISK OF SPONTANEOUS PRE-TERM BIRTH (SPTB)
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Considine, Elizabeth
Dowling, Kirsten
Abrégé
A method for predicting the risk of spontaneous pre-term birth in a patient comprising assaying a biological sample obtained from the patient (at 20 weeks gestation) for abundance of at least one metabolite biomarker.
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Duane, Russell
Jaksic, Aleksandar
Vasovic, Nikola
Abrégé
The present invention provides a radiation dosimeter with improved sensitivity. The sensor apparatus comprises a semiconductor structure, a means for biasing the semiconductor structure to readout stored charge in its dielectric by exhibiting a sensor current-voltage characteristic which is proportional to the dielectric stored charge, and a means for determining a change in current- voltage characteristic of the sensor terminal due to irradiation. The semiconductor substrate comprises a bulk region of a first conductivity type formed in the substrate, a source region and a drain region formed in the bulk region, wherein the source region and the drain region are of a second conductivity type opposite to the first conductivity type, a channel region formed between the source region and the drain region, a dielectric formed on the channel region for storing charge due to irradiation, and a gate electrode formed on the dielectric. The means for biasing configures the semiconductor structure such that the gate electrode and the source region are electrically connected to form a sensor terminal, and the bulk is biased with a fixed voltage such that it is reverse biased with respect to the sensor and the drain, and the drain is biased with a fixed voltage such that it sinks channel current sourced from the sensor terminal, and wherein the channel region is configured to provide a channel current from the sensor to the drain which is larger in magnitude than the reverse biased bulk-sensor and bulk-drain diode currents.
H01L 31/119 - Dispositifs sensibles au rayonnement d'ondes très courtes, p.ex. rayons X, rayons gamma ou rayonnement corpusculaire caractérisés par un fonctionnement par effet de champ, p.ex. détecteurs du type MIS
H01L 31/02 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails - Détails
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Mathuna, Cian
Smallwood, Daniel
Pavlovic, Zoran
Smiddy, Hugh
O'Driscoll, Seamus
Mccloskey, Paul
Abrégé
The present invention provides an inductor device comprising one or more interconnected columns of conductive material embedded in a supporting structure, wherein the one or more columns comprise an input terminal and an output terminal; and wherein each column is surrounded by a first magnetic layer.
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
H05K 1/16 - Circuits imprimés comprenant des composants électriques imprimés incorporés, p.ex. une résistance, un condensateur, une inductance imprimés
44.
A COATING COMPOSITION COMPRISING INTEGRATED FUNCTIONALITY
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, Cork (Irlande)
Inventeur(s)
Morris, Michael A.
Padmanabhan, Sibu C.
Kerry, Joseph P.
Cruz-Romero, Malco
Abrégé
A coating composition for applying a very thin film coating to a substrate such as a polymeric film comprises a copolymer such as a block copolymer (BCP) that is compatible with the substrate, an alcohol solvent or solvents capable of dissolving the copolymer, a hydrolysed metal alkoxide precursor, a carboxylic acid stabiliser, and an active agent in an ionic, molecular, or small nanoparticle form. The active agent is configured to provide a functionality to the coating composition, selected from antimicrobial, antifungal, barrier, therapeutic, electrical, electronic, magnetic and optical. The composition is a sol comprising a continuous non-sedimentable/stable suspension of very small sized (of nano order) amorphous inorganic polymers in their oligomeric or polymeric state, and comprising the active agent dispersed in a hydrolysed metal alkoxide-BCP matrix. Substrates coated with very thin coatings are also provided, including coated LDPE which is activated before coating by UV/ozone, plasma or corona treatment prior to deposition of a wetting layer.
C09D 153/00 - Compositions de revêtement à base de copolymères séquencés possédant au moins une séquence d'un polymère obtenu par des réactions ne faisant intervenir que des liaisons non saturées carbone-carbone; Compositions de revêtement à base de dérivés de tels polymères
B05D 3/06 - Traitement préalable des surfaces sur lesquelles des liquides ou d'autres matériaux fluides doivent être appliqués; Traitement ultérieur des revêtements appliqués, p.ex. traitement intermédiaire d'un revêtement déjà appliqué, pour préparer les applications ultérieures de liquides ou d'autres matériaux fluides par exposition à des rayonnements
B05D 3/14 - Traitement préalable des surfaces sur lesquelles des liquides ou d'autres matériaux fluides doivent être appliqués; Traitement ultérieur des revêtements appliqués, p.ex. traitement intermédiaire d'un revêtement déjà appliqué, pour préparer les applications ultérieures de liquides ou d'autres matériaux fluides par des moyens électriques
B05D 3/10 - Traitement préalable des surfaces sur lesquelles des liquides ou d'autres matériaux fluides doivent être appliqués; Traitement ultérieur des revêtements appliqués, p.ex. traitement intermédiaire d'un revêtement déjà appliqué, pour préparer les applications ultérieures de liquides ou d'autres matériaux fluides par d'autres moyens chimiques
B05D 1/18 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces par immersion
B05D 1/02 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces réalisés par pulvérisation
C08K 5/56 - Composés organométalliques, c. à d. composés organiques contenant une liaison métal-carbone
C09D 5/14 - Peintures contenant des biocides, p.ex. fongicides, insecticides ou pesticides
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Zubialevich, Vitaly, Z.
Parbrook, Peter, J.
Pampilli, Pietro
Abrégé
A semiconductor heterostructure device for use as a component in an optoelectronic component, the device has a substrate, a nanocolumn extending from the substrate, a self-centred passivation layer on top of the nanocolumn, an active region which comprises a quantum well (QW) stack on a vertical side of the nanocolumn and wherein the passivation layer extends horizontally outwards from the nanocolumn to overhang the nanocolumn and the QW stack. The device provides for efficient NC heterostructure based light emitting diodes (LEDs) and other optoelectronic devices with an active region located purely on non-polar facets of the NCs. It also eliminates parasitic current paths allowing core-shell nanorod-based LEDs with emission from the desired facets only.
H01L 33/24 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une forme particulière, p.ex. substrat incurvé ou tronqué de la région électroluminescente, p.ex. jonction du type non planaire
H01L 33/18 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une structure cristalline ou une orientation particulière, p.ex. polycristalline, amorphe ou poreuse au sein de la région électroluminescente
H01L 31/0392 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur structure cristalline ou par l'orientation particulière des plans cristallins comprenant des films minces déposés sur des substrats métalliques ou isolants
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
H01L 33/08 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les corps semi-conducteurs ayant une pluralité de régions électroluminescentes, p.ex. couche électroluminescente discontinue latéralement ou région photoluminescente intégrée au sein du corps semi-conducteur
H01L 33/44 - DISPOSITIFS À SEMI-CONDUCTEURS NON COUVERTS PAR LA CLASSE - Détails caractérisés par les revêtements, p.ex. couche de passivation ou revêtement antireflet
46.
Phase modulator for optical signal using multimode interference couplers
University College Cork—National University Of Ireland, Cork (Irlande)
Inventeur(s)
Peters, Frank
Duggan, Shane
Abrégé
The invention provides an optical system and method for outputting a modulated signal comprising a single multimode interference (MMI) device having at least two inputs configured with a fixed phase and an output, wherein the output modulated signal is controlled by modulating the input power of at 5 least one of the inputs. The invention only requires a single MMI device to operate as the relative phase between the two inputs are fixed relative each other and one of the inputs can be used to modulate the output by modulating the power at a single input. In further embodiments, the invention shows how correct phases can be set by a single MMI device. Thus, no more than two 10 MMIs are required in conjunction with phase or amplitude modulating elements to fully generate a BPSK or QPSK signal.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Mahony, Conor
O'Callaghan, Suzanne
Abrégé
An intelligent laminate dressing system (1) for monitoring and treating a wound made up an absorbent pad (2), a sensor (16) for detecting wound data and an electronic module (17) communicable with the sensor (16), the sensor (16) and the electronic module (17) being positionally offset with respect to the centre of the absorbent pad (2).
A61F 13/00 - Bandages ou pansements; Garnitures absorbantes
A61F 13/42 - Garnitures absorbantes, p.ex. serviettes ou tampons hygiéniques pour application externe ou interne au corps; Moyens pour les maintenir en place ou les fixer; Applicateurs de tampons avec un indicateur ou une alarme d'humidité
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Brien, Peter
Abrégé
The present disclosure is directed towards aligning a photonic integrated circuit (PIC) through providing a PIC with a marker waveguide, wherein a marker waveguide is a waveguide having: a first end located at the edge of the PIC wherein the first end is coupled to an edge coupling; and a second end coupled to a grating coupler or a device coupler, wherein: the grating coupler or device coupler is configured to receive light and couple the light to the waveguide to illuminate the waveguide to facilitate the correct alignment of the edge coupler to an external component.
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
G02B 6/124 - Lentilles géodésiques ou réseaux intégrés
G02B 6/30 - Moyens de couplage optique pour usage entre fibre et dispositif à couche mince
G02B 6/42 - Couplage de guides de lumière avec des éléments opto-électroniques
49.
AN OPTICAL FIBER CATHETER PROBE AND A MANUFACTURING METHOD THEREOF
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Brien, Peter
Abrégé
The catheter probe comprises a catheter tip and a catheter body. The catheter tip comprises a plurality of channels for housing a plurality of optical sensors. Each one of said plurality of optical sensors comprises a ferrule comprising a via, a microlens aligned with said via and attached to said ferrule and an optical fiber for optically coupling said microlens to a monitoring means.
A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments
University College Cork—National University of Ireland Cork (Irlande)
Inventeur(s)
O'Brien, Peter Andrew
Duperron, Matthieu Francois Gabriel
Burke, Ray
Eason, Cormac James
Manley, Kevin
Nunan, Gerard
Abrégé
A surgical system for penetrating and determining a characteristic of tissue. An instrument generates rotational torque, and a drill bit tool body extends along an axis between a distal end to engage tissue and a proximal end to couple to the instrument. An emitter operatively coupled to the instrument emits light. A detector operatively coupled to the instrument detects light. An emission lightguide within the tool body transmits light emitted by the emitter toward the tissue as the instrument rotates the tool body. A detection lightguide within the tool body is spaced from the emission lightguide and transmit light reflected by the tissue toward the detector as the instrument rotates the tool body. The emitter emits light into the emission lightguide along the axis, and the detector detects light reflected from the tissue exiting the detection lightguide transverse to the axis when the tool body is coupled to the instrument.
A61B 17/16 - Ostéoclastes; Forets ou ciseaux pour os; Trépans
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets
The invention relates to a variant nisin peptide, wherein the variant nisin peptide is a modified variant of wild-type nisin, wherein the modification comprises or consists of an amino acid residue modification selected from: i) M17Q or M17A; ii) T2L; and iii) one set of modified hinge residues selected from a) N20H and M21T, b) N20V, M21G, and K22A, c) N20V, M21G, and K22V or d) N20V, M21G, and K22T; or v) combinations of modifications i), ii), and iii), and related medical uses and products comprising such nisin peptides.
C07K 14/315 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Streptococcus (G), p.ex. Enterocoques
A23L 3/3526 - Composés organiques contenant de l'azote
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Konugolu Venkata Sekar, Sanathana
Andersson-Engels, Stefan
Matias, Jean
Komolibus, Katarzyna
Abrégé
An apparatus and method for performing optical characterisation of luminescent particles within a sample is provided. The apparatus comprises a light source (10) configured to produce a first pump beam having a first centre wavelength and a substantially speckle-free beam profile for illuminating, along a first illumination optical (path (101), a sample to thereby produce emitted light by the interaction of the first pump beam with the sample; a first detector (70E) for detecting pump-induced emitted light from a detection region (65) within the sample along a first detection optical path (102); and a first optical filter element in the first detection optical path (102) for attenuating light at the first centre wavelength. The method comprises illuminating the sample with the pump beam having the substantially speckle-free beam profile at a detection region (65) within the sample; and detecting light emitted from the detection region of the sample produced by the interaction of the pump beam with the sample.
G02B 27/09 - Mise en forme du faisceau, p.ex. changement de la section transversale, non prévue ailleurs
G02B 27/48 - Systèmes optiques utilisant la granulation produite par laser
G01N 15/00 - Recherche de caractéristiques de particules; Recherche de la perméabilité, du volume des pores ou de l'aire superficielle effective de matériaux poreux
G01N 15/10 - Recherche de particules individuelles
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Toole, Paul
Jeffery, Ian
Ghosh, Tarini
Tan, Huizi
Perez, Marta
Ntemiri, Alexandra
Abrégé
A probiotic composition is provided comprising at least two isolated bacterial species or comprising a purified bacterial preparation comprising at least two bacterial species, wherein the at least two bacterial species are selected from the group consisting of Coprococcus catus, Eubacterium rectale, Alistipes putredinis, Barnesiella intestinihominis, Roseburia hominis, Dorea longicatena and Faecalibacterium prausnitzii. Also provided are specific isolated bacterial strains and use of the composition for treating frailty and/or inflammation related to aging in elderly subjects.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Toole, Paul
Jeffery, Ian
Ghosh, Tarini
Tan, Huizi
Perez, Marta
Ntemiri, Alexandra
Abrégé
Coprococcus catus, Eubacterium rectale, Alistipes putredinis, Barnesiella intestinihominis, Roseburia hominis, Dorea longicatenaFaecalibacterium prausnitziiFaecalibacterium prausnitzii. Also provided are specific isolated bacterial strains and use of the composition for treating frailty and/or inflammation related to aging in elderly subjects.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Riza, Nabeel, Agha
Abrégé
The present invention provides a method for performing optical image detection using a camera module comprising a Digital MicroMirror Device, a first point Photo Detector, a second point Photo Detector, a first lens and a second lens. The method comprises: mapping incident light onto an image plane of the DMD to form a light irradiance map; selecting N pixels on the DMD for time frequency coding; associating each selected pixel with a unique Walsh code time sequence; time frequency coding by the DMD the optical irradiance values of each selected pixel using a plurality of selected bits of its associated Walsh code time sequence; detecting the time frequency coded optical irradiance values of the selected pixels simultaneously at the first point Photo Detector and at the second point Photo Detector; and performing simultaneous signal processing on the time frequency coded optical irradiance values detected by the first point Photo Detector and by the second point Photo Detector to determine the light intensity of each of the selected pixels and produce an image of the incident light.
H04N 5/335 - Transformation d'informations lumineuses ou analogues en informations électriques utilisant des capteurs d'images à l'état solide [capteurs SSIS]
G01S 17/89 - Systèmes lidar, spécialement adaptés pour des applications spécifiques pour la cartographie ou l'imagerie
56.
METHOD FOR PRODUCING POROUS GRAPHENE OR POROUS GRAPHTIC CARBON
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Burke, Michael
Quinn, Aidan
Iacopino, Daniela
Manning, Mary
Abrégé
A method is provided for producing a porous graphene or porous graphitic carbon material. The method comprised creating a biopolymer-based feedstock material from a biopolymer formulation (8). The bio polymer is derived from a synthetic or naturally occurring mucopolysaccharide or other heteropolysaccharide. The method comprises irradiating the biopolymer-based feedstock material with coherent light (12) to produce porous graphene or porous graphitic carbon.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Faisal, Waleed
Crean, Abina
Abrégé
A microneedle with very high drug loading is described, and comprises a base and a penetrating tip, the tip having a dimension ranging from about 50 nm to about 50 µm, wherein at least 80 % of the microneedle by volume consists of heat-meltable active pharmaceutical ingredient (v/v). The meltable active pharmaceutical ingredient is characterised by being heat-meltable (i.e. it can be heated to a molten form), is solid at 25°C, and has an ability to form a glassy, amorphous form following melting by heating and cooling with a glass transition temperature greater than 25°C. A method of fabricating a microneedle comprises the steps of providing a microneedle micromold comprising a micromold substrate and one or more holes in the upper surface of the micromold substrate, wherein the interior surface of the hole in the micromold substrate defines an exterior surface of the microneedle, moulding a meltable drug in the microneedle micromold to form a microneedle, and separating the microneedle from the microneedle micromold. Microneedles of the invention may incorporate up to 99% drug or more.
A61K 31/496 - Pipérazines non condensées contenant d'autres hétérocycles, p.ex. rifampine, thiothixène
A61K 31/565 - Composés contenant des systèmes cycliques du cyclopenta[a]hydrophénanthrène; Leurs dérivés, p.ex. stéroïdes non substitués en position 17 bêta par un atome de carbone, p.ex. œstrane, œstradiol
UNIVERSITY COLLEGE CORK – NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
JANSSEN BIOTECH, INC. (USA)
Inventeur(s)
Plevy, Scott
Hill, Colin
Shkoporov, Andrey
Clooney, Adam
Sutton, Thomas
Abrégé
A method is described of analyzing the microbiome, including the virome, of a patient. Viral marker clusters for diagnosing inflammatory bowel disease, Crohn's disease and ulcerative colitis are identified from such analysis. Methods of diagnosis and treatment of dysbiosis and various disorders, such as inflammatory bowel disease, Crohn's disease and ulcerative colitis, are also included.
C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Ross, Paul
Stanton, Catherine
Abrégé
A composition for use in a method of regulating or treating a metabolic disease or a symptom thereof, the composition comprising an isolated bacteria Lactobacillus brevis (DPC6108) deposited with the National Collection of Industrial and Marine Bacteria Limited (NCIMB) on 28 November 2011 and accorded the accession number NCIMB 41903.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Stanton, Catherine
Ross, Paul
Fitzgerald, Ger
Ryan, Tony
Abrégé
A composition comprises a cohort of at least five isolated unique strains of a single species of bacteria, wherein the species of bacteria is represented in the mammalian microbiome, and wherein the cohort of isolated strains exhibit different and diverse catabolic capability thereby increasing the chances that one or more of the strains in the composition will find a nutritional niche in the infant GI tract.
University College Cork-National University of Ireland, Cork (Irlande)
Inventeur(s)
O'Brien, Peter
Abrégé
At least one embodiment of the invention provides a photonic subsystem for integrating onto a photonic platform. The subsystem comprises a laser source and a plurality of optical components for focusing and directing a laser beam emitted from the laser source into a photonic platform. The laser source and plurality of optical components are mounted to a substrate and encapsulated.
G02B 27/09 - Mise en forme du faisceau, p.ex. changement de la section transversale, non prévue ailleurs
G02B 3/04 - Lentilles simples ou composées à surfaces non sphériques à surfaces continues engendrées par une rotation autour d'un axe, mais s'écartant d'une véritable sphère
H01S 5/02234 - Boîtiers remplis de résine; Boîtiers en résine
H01S 5/02255 - Découplage de lumière utilisant des éléments de déviation de faisceaux lumineux
05 - Produits pharmaceutiques, vétérinaires et hygièniques
41 - Éducation, divertissements, activités sportives et culturelles
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Dietetic and nutritional products for pre-term infants. Providing training and education in the field of nutrition and diet for pre-term infants. Providing dietary and nutritional advice services in relation to pre-term infants.
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
Produits et services
Software; Touchscreen sensors; Touchscreen monitors; Computer touchscreens. Medical devices; Medical diagnostic instruments; Medical analysis instruments; Medical testing instruments; Medical apparatus and instruments; Detecting instruments for medical use; Analytical instruments for medical use; Diagnostic instruments for medical use; Testing instruments for medical diagnostic purposes. Psychometric testing for medical purposes; Behavioural analysis for medical purposes; Psychotherapy; Psychotherapy services; Personality assessment services [mental health services]; Psychiatric testing; Psychiatric services; Preparing psychological profiles; Preparation of psychological profiles for medical purposes; Psychological assessment services; Conducting of psychological assessments and examination; Psychological assessment and examination services; Occupational psychology services; Personality testing for psychological purposes; Preparation of psychological reports; Provision of information relating to psychology; Psychological consultation; Psychological diagnosis services; Psychological profiles for medical purposes (Preparation of -); Psychological testing; Psychological testing for medical purposes; Psychological testing services; Psychological tests; Psychological therapy for infants; Medical health assessment services; Medical analysis services; Medical advisory services; Medical care services; Medical diagnostic services; Medical evaluation services; Medical testing for diagnostic or treatment purposes; Medical testing; Providing medical information; Provision of medical services.
64.
Monolithic integrated mesh device for fluid dispensers and method of making same
University College Cork—National University of Ireland (Irlande)
Inventeur(s)
Jackson, Nathan
Mathewson, Alan
Olszewski, Zbigniew
Abrégé
The invention provides a monolithic integrated mesh device for atomization or pumping of a fluid or liquid comprising a plurality of apertures and a piezoelectric material. The piezoelectric material is bonded to the mesh device at an atomic scale. In one embodiment the monolithic micro-fabricated device of the invention includes piezoelectric material that eliminates the need for expensive assembly process and improves reliability. This also has advantage of requiring lower operating voltage and less complicated circuitry.
B05B 17/06 - Appareils de pulvérisation ou d'atomisation de liquides ou d'autres matériaux fluides, non couverts par les autres groupes de la présente sous-classe opérant suivant des procédés particuliers utilisant des vibrations ultrasonores
B05B 17/00 - Appareils de pulvérisation ou d'atomisation de liquides ou d'autres matériaux fluides, non couverts par les autres groupes de la présente sous-classe
65.
Bifidobacterium longum for treating obesity and weight management
UNIVERSITY COLLEGE CORK—NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Cryan, John
Dinan, Ted
Stanton, Catherine
Schellekens, Harriet
Torres, Cristina
Roy, Bernard
Abrégé
Bifidobacterium longum APC 1472 is described. The strain has weight lowering effects in-vivo, achieved through inducing satiety via decreased internalisation of the Ghrelin receptor, and therefore, decreased constitutive activity. Moreover, the strain also showed a trend towards decreased ghrelin receptor hypothalamic expression in HFD-fed mice when compared with vehicle control group. The strain also improves glucose tolerance and decreased insulin plasma levels in mice, indicating the strain in the prevention and/or treatment of Type II diabetes, especially in obese individuals.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
TEAGASC, THE AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (Irlande)
Inventeur(s)
Ross, Reynolds Paul
Stanton, Catherine
Hill, Colin
Ryan, Anthony
O'Sullivan, Julie
Watkins, Claire
Abrégé
An isolated lantibiotic is provided comprising amino acid sequence SEQ. ID No. 2 and at least one of amino acid sequences SEQ. ID No. 4 and SEQ. ID. No 6. Also provided is use of the lantibiotic in the treatment or prevention of infection by Group B Streptococcus or Corynebacterium xerosis. The invention further relates to isolated S. hominis strains and use of same in producing the lantibiotic. A vector is provided comprising nucleotides sequences for producing the lantibiotic.
A61K 38/16 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés
C07K 14/31 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de bactéries provenant de Micrococcaceae (F) provenant de Staphylococcus (G)
University College Cork-National University of Ireland, Cork (Irlande)
Inventeur(s)
Holmes, Justin
Morris, Michael
Hanrahan, John
Keane, Donal
Copley, Mark
Abrégé
A method for synthesizing mesoporous silica microparticles comprising the steps of: preparing a sol from an ammonium catalyzed hydrolysis and condensation reaction of a pre-sol solution comprising a silica precursor and a structure directing agent dissolved in a mixed solvent system comprising an alcohol and water to produce mesoporous particles of silica with an average diameter of up to about 50 μm; hydrothermally treating the particles to increase the pore size; treating the particles to remove residual structure directing agent; and further increasing the pore size using controlled dissolution.
University College Cork—National University of Ireland, Cork (Irlande)
Inventeur(s)
Donnelly, Yann
Kennedy, Michael Peter
Abrégé
The present invention provides a probability mass redistributor device comprising an input port and an output port. The device comprises a mapping block configured to perform a selected mapping function from a plurality of mapping functions on a random bitstream to generate an output signal having a desired probability mass function, at least one difference block, wherein the input to the at least one difference block comprises the output from the mapping block, and the output of the at least one difference block produces a modulation term, and wherein the output of each difference block is the difference between a previous value of the input signal to the block and a current value of the input signal to the block, and a summing block for summing a signal received by the input port and the modulation term to form an output signal.
H03L 7/197 - Synthèse de fréquence indirecte, c. à d. production d'une fréquence désirée parmi un certain nombre de fréquences prédéterminées en utilisant une boucle verrouillée en fréquence ou en phase en utilisant un diviseur de fréquence ou un compteur dans la boucle une différence de temps étant utilisée pour verrouiller la boucle, le compteur comptant entre des nombres variables dans le temps ou le diviseur de fréquence divisant par un facteur variable dans le temps, p.ex. pour obtenir une division de fréquence
G06F 17/18 - Opérations mathématiques complexes pour l'évaluation de données statistiques
H03M 3/00 - Conversion de valeurs analogiques en, ou à partir d'une modulation différentielle
69.
System and method for throughput prediction for cellular networks
University College Cork—National University of Ireland (Irlande)
Inventeur(s)
Jana, Rittwik
Halepovic, Emir
Sinha, Rakesh
Gopalakrishnan, Vijay
Zahran, Ahmed
Raca, Darijo
Sreenan, Cormac John
Bathula, Balagangadhar G.
Varvello, Matteo
Abrégé
Aspects of the subject disclosure may include, for example, a method in which a processing system identifies a plurality of performance indicators comprising device performance indicators for a plurality of communication devices on a cellular network and network performance indicators for the cellular network. The method also includes obtaining historical data regarding the plurality of performance indicators for each of a series of time points during a past time period; the historical data for each of the plurality of performance indicators form an array of values for that performance indicator. The method further includes generating from each array a set of inputs to an algorithm for predicting a throughput of the cellular network during a future time period; the set of inputs comprises quantiles of the array, and the algorithm comprises a machine learning algorithm. Other embodiments are disclosed.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
ALTRATECH LIMITED (Irlande)
Inventeur(s)
O'Farrell, Brian
O'Connell, Ivan
Darby, Steven
Cummins, Timothy
Abrégé
A diagnostic sensor device has a semiconductor chip having a distal end physically configured to fit into a power and data socket conforming to a non-proprietary standard, and having exposed pads for engagement with corresponding conductors of such a socket. At its proximal end the chip has at least one sensor for contact with an analyte. The device may be manufactured in a single integrated process to provide a wafer which is diced to provide the individual devices.
A23L 33/135 - Bactéries ou leurs dérivés, p.ex. probiotiques
A23L 33/00 - Modification de la qualité nutritive des aliments; Produits diététiques; Leur préparation ou leur traitement
A23C 9/123 - Préparations à base de lait fermenté; Traitements utilisant des micro-organismes ou des enzymes ne comportant que des micro-organismes de la famille des lactobactériacées; Yoghourt
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Papkovsky, Dmitri
Fercher, Andreas
Klimant, Ingo
Borisov, Sergey
Zhdanov, Alexander
Abrégé
A method of determining oxygen concentration, metabolic activity, and/or the effects of a test substance on the metabolic activity of a live cell sample by photoluminescence quenching technique employing a photoluminescent probe that self-loads sans any loading reagent into the cells of the cell sample. The probe comprises a plurality of polymeric particles each comprising an amphiphilic cationic polymer matrix having a hydrophobic core and a hydrophilic positively charged surface provided by quaternary amino groups, and a hydrophobic oxygen-sensitive photoluminescent dye embedded in the hydrophobic core.
G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique
B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites
G01N 33/84 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des composés inorganiques ou le pH
G01N 33/58 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des substances marquées
73.
A VERTICAL MAGNETIC STRUCTURE FOR INTEGRATED POWER CONVERSION
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Mathuna, Cian
Smallwood, Daniel
Pavlovic, Zoran
Smiddy, Hugh
O'Driscoll, Seamus
Mccloskey, Paul
Abrégé
The present invention provides an inductor device comprising one or more interconnected columns of conductive material embedded in a supporting structure, wherein the one or more columns comprise an input terminal and an output terminal; and wherein each column is surrounded by a first magnetic layer.
H01F 41/04 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants pour la fabrication de bobines
H05K 1/16 - Circuits imprimés comprenant des composants électriques imprimés incorporés, p.ex. une résistance, un condensateur, une inductance imprimés
University College Cork—National University of Ireland (Irlande)
Inventeur(s)
Jana, Rittwik
Halepovic, Emir
Sinha, Rakesh
Gopalakrishnan, Vijay
Zahran, Ahmed
Raca, Darijo
Sreenan, Cormac John
Bathula, Balagangadhar G.
Varvello, Matteo
Abrégé
Aspects of the subject disclosure may include, for example, a method in which a processing system identifies a plurality of performance indicators comprising device performance indicators for a plurality of communication devices on a cellular network and network performance indicators for the cellular network. The method also includes obtaining historical data regarding the plurality of performance indicators for each of a series of time points during a past time period; the historical data for each of the plurality of performance indicators form an array of values for that performance indicator. The method further includes generating from each array a set of inputs to an algorithm for predicting a throughput of the cellular network during a future time period; the set of inputs comprises quantiles of the array, and the algorithm comprises a machine learning algorithm. Other embodiments are disclosed.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Maguire, Anita
Gavin, Declan
O'Gara, Fergal
Reen, Jerry
Abrégé
An isolated w-transaminase enzyme comprising an amino acid sequence of SEQUENCE ID NO: 1, or encoded by a nucleic acid sequence of SEQUENCE ID NO: 2, is provided which is derived from marine sponge Pseudovibrio sp.. Also provided are functional variants of the w-transaminase enzyme that are isolated, have at least 80% sequence identity with SEQUENCE ID NO: 1, and are capable of enantioselectively resolving a racemic amine by transformation to a ketone by oxidative deamination, or enantioselectively resolving a racemic ketone by transformation to an amine by reductive amination, in which the amine and ketone typically contain a stereocentre removed from the reacting site. An example of a functional variant is SEQUENCE ID NO:3. In one embodiment, the functional variant is capable of enantioselectively transforming a (4S) -tetralone intermediate in the synthesis of sertraline, in which the functional variant displays remote stereospecificity for the tetralone intermediate.
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Peters, Frank
Duggan, Shane
Abrégé
The invention provides an optical system and method for outputting a modulated signal comprising a single multimode interference (MMI) device having at least two inputs configured with a fixed phase and an output, wherein the output modulated signal is controlled by modulating the input power of at 5 least one of the inputs. The invention only requires a single MMI device to operate as the relative phase between the two inputs are fixed relative each other and one of the inputs can be used to modulate the output by modulating the power at a single input. In further embodiments, the invention shows how correct phases can be set by a single MMI device. Thus, no more than two 10 MMIs are required in conjunction with phase or amplitude modulating elements to fully generate a BPSK or QPSK signal.
H04B 10/556 - Modulation numérique, p.ex. modulation par déplacement de phase différentielle [DPSK] ou modulation par déplacement de fréquence [FSK]
G02F 1/225 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p.ex. commutation, ouverture de porte ou modulation; Optique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur par interférence dans une structure de guide d'ondes optique
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Mahony, Conor
O'Callaghan, Suzanne
Abrégé
An intelligent laminate dressing system (1) for monitoring and treating a wound made up an absorbent pad (2), a sensor (16) for detecting wound data and an electronic module (17) communicable with the sensor (16), the sensor (16) and the electronic module (17) being positionally offset with respect to the centre of the absorbent pad (2).
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Morris, Michael A.
Padmanabhan, Sibu C.
Kerry, Joseph P.
Cruz-Romero, Malco
Abrégé
A coating composition for applying a very thin film coating to a substrate such as a polymeric film comprises a copolymer such as a block copolymer (BCP) that is compatible with the substrate, an alcohol solvent or solvents capable of dissolving the copolymer, a hydrolysed metal alkoxide precursor, a carboxylic acid stabiliser, and an active agent in an ionic, molecular, or small nanoparticle form. The active agent is configured to provide a functionality to the coating composition, selected from antimicrobial, antifungal, barrier, therapeutic, electrical, electronic, magnetic and optical. The composition is a sol comprising a continuous non-sedimentable/stable suspension of very small sized (of nano order) amorphous inorganic polymers in their oligomeric or polymeric state, and comprising the active agent dispersed in a hydrolysed metal alkoxide-BCP matrix. Substrates coated with very thin coatings are also provided, including coated LDPE which is activated before coating by UV/ozone, plasma or corona treatment prior to deposition of a wetting layer.
C09D 1/00 - Compositions de revêtement, p.ex. peintures, vernis ou vernis-laques, à base de substances inorganiques
C09D 5/00 - Compositions de revêtement, p.ex. peintures, vernis ou vernis-laques, caractérisées par leur nature physique ou par les effets produits; Apprêts en pâte
C09D 5/14 - Peintures contenant des biocides, p.ex. fongicides, insecticides ou pesticides
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Donadei, Agnese
Flynn, Olivia
Moore, Anne
Abrégé
A composition for stabilising a vaccine in a solid dosage format is provided wherein the composition comprises an antioxidant, such as glutathione, a monosaccharide or disaccharide sugar, such as trehalose, a polyol sugar, such as sorbitol, one or more salts, such as magnesium chloride and sodium glutamate, and a vaccine. The composition may also comprise an aqueous soluble polymer, such as polyvinyl alcohol (PVA). A preferred composition comprises 40 mM glutathione,20% w/v trehalose,3% w/v sorbitol, 1.5% w/v PVA,3% w/v magnesium chloride and 3% w/v sodium glutamate. Also provided is a method of stabilising a vaccine in a solid dosage format, the method comprising drying the stabilising composition to provide the vaccine in the solid dosage format. The composition and method may be used to stabilise any suitable vaccine, such as poliovirusor adenovirus, in a solid dosage format, such as microneedle patches or wafers.
C08L 29/04 - Alcool polyvinylique; Homopolymères ou copolymères d'esters partiellement hydrolysés d'alcools non saturés avec des acides carboxyliques saturés
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
Walter, Thomas
Abrégé
A peptide comprises an amino acid sequence of SEQUENCE ID NO. 1, in which the sequence has 1, 2 or 3 amino acid changes. The peptide has utility in treatment of cardiovascular disease and neurodegenerative disease.
University College Cork—National University of Ireland (Irlande)
Inventeur(s)
O'Gara, Fergal
Reen, Jerry F.
Mcglacken, Gerard
Abrégé
An antibiofilm composition comprising a compound of formula (A1), (A2) or (A3):
7 is independently selected from hydrogen, alkyl, alkenyl, aryl, halo, alkoxy, hydroxyl, amino, nitro, sulfoxy, thiol, carboxy, alkyl carboxy and amido; and X may be O or S, wherein the composition does not comprise a compound of formula (B1) or (B2):
C07D 239/91 - Atomes d'oxygène avec des radicaux aryle ou aralkyle liés en position 2 ou 3
C07C 215/38 - Composés contenant des groupes amino et hydroxy liés au même squelette carboné ayant des groupes hydroxy et des groupes amino liés à des atomes de carbone acycliques du même squelette carboné le squelette carboné étant non saturé et contenant des cycles aromatiques à six chaînons avec des cycles autres que des cycles aromatiques à six chaînons faisant partie du squelette carboné
A61P 31/00 - Agents anti-infectieux, c. à d. antibiotiques, antiseptiques, chimiothérapeutiques
83.
Fiber-less photonic system in an integrated package
The invention provides a photonic package system comprising at least two optical alignment pins integrated on a package substrate. A key feature of this invention is the addition of alignment structures within the package. When combined with the use of micro optics it enables a ‘fiber-less’ photonic package system that requires no physical connection between and optical fiber and the photonic package system.
G02B 6/42 - Couplage de guides de lumière avec des éléments opto-électroniques
G02B 1/00 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES Éléments optiques caractérisés par la substance dont ils sont faits; Revêtements optiques pour éléments optiques
H05K 3/00 - Appareils ou procédés pour la fabrication de circuits imprimés
University College Cork—National University of Ireland, Cork (Irlande)
Inventeur(s)
Riza, Nabeel
Abrégé
The present invention provides a method for performing high dynamic range low inter-pixel spatial and wavelength crosstalk optical image detection in a camera comprising an Optical Array Device (OAD), a point Photo Detector (PD) and a Photo Detector Array (PDA) sensor. The method comprises imaging incident light from an object onto an image plane of the Optical Array Device (OAD) to form an incident image map; selecting by the OAD and the Point Photo Detector and by the OAD and the Photo Detector Array a plurality of pixels on the incident image map for time-frequency coding; time-frequency coding the selected pixels by the OAD; detecting by the point PD the optical irradiance values of the time-frequency coded pixels output from the OAD; and performing signal processing on the detected optical irradiance values to determine the light intensity of each of the selected pixels.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Stanton, Catherine
Ross, Paul
Fitzgerald, Ger
Ryan, Tony
Abrégé
A composition comprises a cohort of at least five isolated unique strains of a single species of bacteria, wherein the species of bacteria is represented in the mammalian microbiome, and wherein the cohort of isolated strains exhibit different and diverse catabolic capability thereby increasing the chances that one or more of the strains in the composition will find a nutritional niche in the infant GI tract.
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Stanton, Catherine
Ross, Paul
Fitzgerald, Ger
Ryan, Tony
Abrégé
A composition comprises a cohort of at least five isolated unique strains of a single species of bacteria, wherein the species of bacteria is represented in the mammalian microbiome, and wherein the cohort of isolated strains exhibit different and diverse catabolic capability thereby increasing the chances that one or more of the strains in the composition will find a nutritional niche in the infant GI tract.
University College Cork—National University of Ireland, Cork (Irlande)
Inventeur(s)
Riza, Nabeel Agha
Abrégé
The present invention provides a method for performing high dynamic range optical image detection of a scene comprising: imaging incident light from a scene onto an object plane; determining the locations of those pixels in the object plane of higher brightness; detecting the optical irradiance values of those pixels of higher brightness to produce a first detected image; detecting the optical irradiance values of those pixels of lower brightness to produce a second detected image; and generating a high dynamic range optical irradiance map of the scene by combining the first detected image and the second detected image into a single image.
H04N 5/235 - Circuits pour la compensation des variations de la luminance de l'objet
G03B 17/17 - Corps d'appareils avec des réflecteurs disposés sur le parcours lumineux formant l'image photographique, p.ex. pour réduire les dimensions de l'appareil photographique
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
ALTRATECH LIMITED (Irlande)
Inventeur(s)
Cummins, Timothy
O'Farrell, Brian
Darby, Steven
O'Connell, Ivan
Abrégé
A diagnostic sensor device (1) has a semiconductor chip (2) having a distal end physically configured to fit into a power and data socket (10) conforming to a non-proprietary standard, and having exposed pads (3) for engagement with corresponding conductors of such a socket. At its proximal end the chip has at least one sensor (5) for contact with an analyte. The device may be manufactured in a single integrated process to provide a wafer (9) which is diced to provide the individual devices.
The present invention relates to a method for the treatment of cancer in a subject which comprises the steps of: (i) administering electroporation to a tumour in the subject; and (II) administering a T or B-cell activiating agent to the subject, wherein step (i) and (II) may be performed in either order.
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p.ex. composés antiphlogistiques et pour le cœur
A61M 37/00 - Autres appareils pour introduire des agents dans le corps; Percutanisation, c. à d. introduction de médicaments dans le corps par diffusion à travers la peau
91.
BIFIDOBACTERIUM LONGUM FOR TREATING OBESITY AND WEIGHT MANAGEMENT
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Cryan, John
Dinan, Ted
Stanton, Catherine
Schellekens, Harriet
Torres, Cristina
Roy, Bernard
Abrégé
A strain of Bifidobacterium longum APC 1472 is described. The strain has weight lowering effects in-vivo, achieved through inducing satiety via decreased internalisation of the Ghrelin receptor, and therefore, decreased constitutive activity. Moreover, the strain also showed a trend towards decreased ghrelin receptor hypothalamic expression in HFD-fed mice when compared with vehicle control group. The strain also improves glucose tolerance and decreased insulin plasma levels in mice, indicating the strain in the prevention and/or treatment of Type II diabetes, especially in obese individuals.
University College Cork-National University of Ireland, Cork (Irlande)
Inventeur(s)
Mo, Hongjia
Kennedy, Michael Peter
Abrégé
A nested mixed-radix DDSM can guarantee zero systematic frequency error when used as a divider controller in a fractional-N frequency synthesizer is described. This disclosure presents a nested cascaded mixed-radix DDSM architecture which can also guarantee zero systematic frequency error. In addition, the disclosure allows one to use higher order auxiliary modulators and shaped dither signal to eliminate feedthrough spurs completely. By increasing the number of levels in the cascade, the moduli of the individual modulator stages can be reduced, thereby increasing the speed of the synthesizer.
H03L 7/197 - Synthèse de fréquence indirecte, c. à d. production d'une fréquence désirée parmi un certain nombre de fréquences prédéterminées en utilisant une boucle verrouillée en fréquence ou en phase en utilisant un diviseur de fréquence ou un compteur dans la boucle une différence de temps étant utilisée pour verrouiller la boucle, le compteur comptant entre des nombres variables dans le temps ou le diviseur de fréquence divisant par un facteur variable dans le temps, p.ex. pour obtenir une division de fréquence
H03M 7/36 - Conversion en, ou à partir d'une modulation différentielle à plusieurs bits, c. à d. la différence entre des échantillons successifs étant codée par plus d'un bit
H03M 3/00 - Conversion de valeurs analogiques en, ou à partir d'une modulation différentielle
H03L 7/093 - Commande automatique de fréquence ou de phase; Synchronisation utilisant un signal de référence qui est appliqué à une boucle verrouillée en fréquence ou en phase - Détails de la boucle verrouillée en phase concernant principalement l'agencement de détection de phase ou de fréquence y compris le filtrage ou l'amplification de son signal de sortie utilisant des caractéristiques de filtrage ou d'amplification particulières dans la boucle
93.
BIFIDOBACTERIUM LONGUM FOR TREATING OBESITY AND WEIGHT MANAGEMENT
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY (TEAGASC) (Irlande)
Inventeur(s)
Cryan, John
Dinan, Ted
Stanton, Catherine
Schellekens, Harriet
Torres, Cristina
Roy, Bernard
Abrégé
Bifidobacterium longumin-vivoin-vivo, achieved through inducing satiety via decreased internalisation of the Ghrelin receptor, and therefore, decreased constitutive activity. Moreover, the strain also showed a trend towards decreased ghrelin receptor hypothalamic expression in HFD-fed mice when compared with vehicle control group. The strain also improves glucose tolerance and decreased insulin plasma levels in mice, indicating the strain in the prevention and/or treatment of Type II diabetes, especially in obese individuals.
University College Cork, National University of Ireland, Cork (Irlande)
Inventeur(s)
Kenny, Louise
Baker, Philip Newton
Broadhurst, David
Abrégé
A method for the early prediction of risk of hypertensive disorders in pregnant women, including for example eclampsia, mild pre-eclampsia, chronic hypertension, EPH gestosis, gestational hypertension, superimposed pre-eclampsia, HELLP syndrome, or nephropathy.
G01N 33/493 - Analyse physique de matériau biologique de matériau biologique liquide d'urine
G16B 40/00 - TIC spécialement adaptées aux biostatistiques; TIC spécialement adaptées à l’apprentissage automatique ou à l’exploration de données liées à la bio-informatique, p.ex. extraction de connaissances ou détection de motifs
G16B 99/00 - Matière non prévue dans les autres groupes de la présente sous-classe
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND CORK (Irlande)
Inventeur(s)
O'Brien, Peter Andrew
Duperron, Matthieu Francois Gabriel
Burke, Ray
Eason, Cormac James
Manley, Kevin
Nunan, Gerard
Abrégé
A surgical system for penetrating and determining a characteristic of tissue. An instrument generates rotational torque, and a drill bit tool body extends along an axis between a distal end to engage tissue and a proximal end to couple to the instrument. An emitter operatively coupled to the instrument emits light. A detector operatively coupled to the instrument detects light. An emission lightguide within the tool body transmits light emitted by the emitter toward the tissue as the instrument rotates the tool body. A detection lightguide within the tool body is spaced from the emission lightguide and transmit light reflected by the tissue toward the detector as the instrument rotates the tool body. The emitter emits light into the emission lightguide along the axis, and the detector detects light reflected from the tissue exiting the detection lightguide transverse to the axis when the tool body is coupled to the instrument.
A61B 17/16 - Ostéoclastes; Forets ou ciseaux pour os; Trépans
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
B23B 49/00 - Systèmes de mesure ou de calibrage des machines à aléser, pour le positionnement ou le guidage du foret; Dispositif pour indiquer les défauts des forets pendant l'alésage; Dispositifs à centrer les trous à aléser
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND CORK (Irlande)
Inventeur(s)
O'Brien, Peter Andrew
Duperron, Matthieu Francois Gabriel
Burke, Ray
Eason, Cormac James
Manley, Kevin
Nunan, Gerard
Abrégé
A surgical system for penetrating and determining a characteristic of tissue. An instrument generates rotational torque, and a drill bit tool body extends along an axis between a distal end to engage tissue and a proximal end to couple to the instrument. An emitter operatively coupled to the instrument emits light. A detector operatively coupled to the instrument detects light. An emission lightguide within the tool body transmits light emitted by the emitter toward the tissue as the instrument rotates the tool body. A detection lightguide within the tool body is spaced from the emission lightguide and transmit light reflected by the tissue toward the detector as the instrument rotates the tool body. The emitter emits light into the emission lightguide along the axis, and the detector detects light reflected from the tissue exiting the detection lightguide transverse to the axis when the tool body is coupled to the instrument.
A61B 17/16 - Ostéoclastes; Forets ou ciseaux pour os; Trépans
B23B 49/00 - Systèmes de mesure ou de calibrage des machines à aléser, pour le positionnement ou le guidage du foret; Dispositif pour indiquer les défauts des forets pendant l'alésage; Dispositifs à centrer les trous à aléser
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (Irlande)
Inventeur(s)
O'Dwyer, Colm
Abrégé
The invention provides plastic 3D printed battery cell comprising a first layer coupled with a cathode material and a second layer coupled with an anode material. An aqueous electrolyte gel material is deposited onto the surface of the cathode material and the anode material, wherein the first and second layers are sealed to house the cathode material, the anode material and the electrolyte gel material. The invention provides a combination of a customisable plastic battery cell design using 3D printing with an all-in-one gel electrolyte enable the cells to be built in a variety of sizes and shapes allowing for greater integration of energy storage into electronic, medical or wearable systems. A method for making the 3D printed battery cell is also described.
H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
H01M 4/131 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif Électrodes pour accumulateurs à électrolyte non aqueux, p.ex. pour accumulateurs au lithium; Leurs procédés de fabrication Électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p.ex. LiCoOx
H01M 4/1391 - Procédés de fabrication d'électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p.ex. LiCoOx
H01M 4/36 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs
H01M 4/525 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de nickel, de cobalt ou de fer d'oxydes ou d'hydroxydes mixtes contenant du fer, du cobalt ou du nickel pour insérer ou intercaler des métaux légers, p.ex. LiNiO2, LiCoO2 ou LiCoOxFy
H01M 4/485 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques d'oxydes ou d'hydroxydes mixtes pour insérer ou intercaler des métaux légers, p.ex. LiTi2O4 ou LiTi2OxFy
H01M 4/62 - Emploi de substances spécifiées inactives comme ingrédients pour les masses actives, p.ex. liants, charges
H01M 2/06 - Dispositions pour introduire des connecteurs électriques dans ou à travers des bacs
H01M 10/0565 - Matériaux polymères, p.ex. du type gel ou du type solide
H01M 10/056 - Accumulateurs à électrolyte non aqueux caractérisés par les matériaux utilisés comme électrolytes, p.ex. électrolytes mixtes inorganiques/organiques
98.
Method for the production of poly(methyl methacrylate) (PMMA) membranes and uses thereof
The Provost, Fellows, Scholars and Other Members of Board of Trinity College Dublin (Irlande)
University College Cork—National University of Ireland, Cork (Irlande)
Inventeur(s)
Fleming, Peter
Morris, Michael
Fitzgerald, Thomas
Padamati, Ramesh Babu
Delaney, Paul
Ngan, Clifton
Hennessy, Niamh
Beyzavi, Kamran
Abrégé
A poly(methyl methacrylate) (PMMA) membrane having a highly porous, reticulated, 3-D structure suitable for lateral flow diagnostic applications is described. Also described is a method for producing a poly(methyl methacrylate) (PMMA) membrane that comprises the steps of mixing a suitable amount of PMMA, a solvent and a optionally one of either a co-solvent or a non-solvent to produce a solution, casting a thin film of the solution onto a support, and removal of the solvent from the solution to produce the PMMA membrane. A lateral flow diagnostic device comprising a highly porous PMMA membrane as a reaction membrane is also described.
B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique
B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétés; Procédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
B01D 71/40 - Polymères d'acides non saturés ou de leurs dérivés, p.ex. sels, amides, imides, nitriles, anhydrides, esters
G01N 33/543 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
A tunnel field effect transistor (100) comprises a source region (102), a drain region (104), and a channel region (106) formed of a single material, in particular a half-metal. The channel extends between the source region and the drain region. The channel region (106) and the drain region (104) are smaller than a threshold size in a first dimension. The threshold size is the size required for the material to exhibit sufficient quantum confinement such that a non-zero band gap results and the material becomes a semiconductor. The source region (102) is larger than this threshold size in the first dimension and is thus metallic.
H01L 29/06 - Corps semi-conducteurs caractérisés par les formes, les dimensions relatives, ou les dispositions des régions semi-conductrices
H01L 31/00 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails
B82Y 10/00 - Nanotechnologie pour le traitement, le stockage ou la transmission d’informations, p.ex. calcul quantique ou logique à un électron
H01L 29/26 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, des éléments couverts par plusieurs des groupes , , , ,
H01L 29/739 - Dispositifs du type transistor, c.à d. susceptibles de répondre en continu aux signaux de commande appliqués commandés par effet de champ
H01L 29/775 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à une dimension, p.ex. FET à fil quantique
H01L 29/78 - Transistors à effet de champ l'effet de champ étant produit par une porte isolée
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
A rectifying junction (15) is formed in a conduction path provided in a material (1). A size of the material (1) is smaller than a threshold size in a first dimension, the threshold size being the size required for the material (1) to exhibit sufficient quantum confinement such that it forms a semiconductor. A surface of a first region (17) of the material (1) is arranged to decrease the bandgap of the material such that the first region is conducting. A surface of a second region (19) of the material (1) is arranged to preserve a bandgap such that the second region is semiconducting. The second region (19) is contiguous to the first region (17), such that a rectifying junction (15) is formed at a boundary (21) between the first region and the second region.
H01L 29/06 - Corps semi-conducteurs caractérisés par les formes, les dimensions relatives, ou les dispositions des régions semi-conductrices
B82Y 10/00 - Nanotechnologie pour le traitement, le stockage ou la transmission d’informations, p.ex. calcul quantique ou logique à un électron
H01L 29/36 - Corps semi-conducteurs caractérisés par la concentration ou la distribution des impuretés
B82Y 40/00 - Fabrication ou traitement des nanostructures
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
H01L 29/739 - Dispositifs du type transistor, c.à d. susceptibles de répondre en continu aux signaux de commande appliqués commandés par effet de champ