The invention relates to a method for inspecting a coated surface for a surface defect. The method comprises: using (102) a device (200, 300, 400, 700, 800, 900) for covering the coated surface to be inspected, the device being configured to create an enclosed space to isolate the surface coating to be inspected from ambient illumination in order to provide predefined photographic acquisition conditions within the enclosed space; acquiring (104) a photo of the coated surface being within the enclosed space; and inspecting (106) the photo for the presence of the surface defect.
A process can be used for producing foam panels, for the production of foam films, composed of a polymer having a glass transition temperature Tg of at least 100° C. An average cell diameter of the foam panels measured according to the standard ASTM D 3576 is between 20 μm and 250 μm, and less than 20 cells having a diameter >260 μm are present per m2. The elongation at break of the foam is 4%-13% measured according to ASTM D 638.
A water based composition contains a sugar based delivery system, coemulsifiers, a positively charged molecule, oil, optional auxiliary materials, and optional lipophilic active ingredients. The composition is encapsulated to be used in personal care products including cosmetics. The composition is penetrating into the skin and is, depending on the active included, able to stabilize the substance and reduce its irritation potential.
A61Q 17/00 - Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
Compositions may be used in treating or preventing a virus infection in a subject, wherein the virus is from the Coronaviridae family and wherein the composition includes an extract of black currants and/or bilberries. The black currants may be the fruit of Ribes nigrum, and/or the bilberries may be the fruit of Vaccinium myrtillus. The extract may be of the pomaces of the black currants and/or the bilberries.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 9/00 - Medicinal preparations characterised by special physical form
A method for manufacturing a porous membrane suitable for use as a separator of a lithium ion battery, comprising the following steps: 1) compounding a polymer and hydrophobic filler by dry mixing; 2) extruding the compounded mixture to obtain a cast film and 3) stretching the cast film to obtain the porous membrane. A porous membrane suitable for use as a separator of a lithium ion battery, a separator for a lithium ion battery, a lithium ion battery, and a device are also provided.
The present invention relates to a method for making a transition metal oxide coated with an at least partially amorphous lithium-containing coating and a method for making an at least partially amorphous lithium-containing powder as well as the coated transition metal oxide and the lithium-containing powder obtainable by these methods. The present invention further relates to an electrode, electrolyte, or energy-storage device, such as a lithium-ion solid-state battery, comprising the coated transition metal oxide.
A process can be used for the preparation of an up-conversion phosphor of the general formula (I)
A process can be used for the preparation of an up-conversion phosphor of the general formula (I)
A process can be used for the preparation of an up-conversion phosphor of the general formula (I)
The process involves providing i) at least one lanthanoid salt, ii) a silicate or a silicon dioxide, iii) at least one alkaline earth metal salt and at least one alkali metal salt, and iv) at least one flux. The process then involves either mixing components i), ii), iii) and iv) by grinding to obtain a mixture; or mixing components i), ii), iii) and iv) in an organic polar or nonpolar solvent that is not a protic solvent by grinding to obtain a mixture, and precalcining the mixture. The process further involves calcining the mixture, and obtaining a silicate-based up-conversion phosphor of the general formula (I), preferably after cooling the material. At least 3.5% by weight of flux is used, based on the total amount of the reactants.
A process can be used for the preparation of an up-conversion phosphor of the general formula (I):
A process can be used for the preparation of an up-conversion phosphor of the general formula (I):
A1-x-y-zB*yB2SiO4:Ln1x,Ln2z, (I).
A process can be used for the preparation of an up-conversion phosphor of the general formula (I):
A1-x-y-zB*yB2SiO4:Ln1x,Ln2z, (I).
The process involves preparing a mixture, introducing the mixture into a reaction chamber of a thermal apparatus, heating the mixture until a thermal treatment temperature is reached with a heating ramp, thermally treating the heated mixture for a holding time of at least 0.02 h, cooling the thermally treated material to room temperature while maintaining a cooling ramp, and obtaining a silicate-based lanthanoid ion-doped phosphor according to formula (I).
A modified method for preparing guanidino acetic acid (GAA) involves reacting cyanamide with an excess molar amount of glycine in an aqueous reaction mixture, in the presence of a base. The method avoids high molar amounts of base or acid for pH control, and maintains the reaction selectivity and product yields.
C07C 279/14 - Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
The invention provides fumed silica granules having a BET surface area of 20 m2/g to 500 m2/g; a number average particle size d50 of 350 μm to 2000 μm; a span (d90−d10)/d50 of particle size distribution of 0.8-3.0; a bulk density of more than 0.35 g/mL; a pore volume for pores >4 nm of not more than 1.5 cm3/g, process for its preparation and use thereof as a catalyst carrier, a carrier for liquid substances, in cosmetic applications, for thermal insulation, as pharmaceutical excipient, in producing thermally treated silica granules, as an abrasive, as a component of a silicone rubber.
Polyether ether ketone copolymers can have the following formula (I),
Polyether ether ketone copolymers can have the following formula (I),
Polyether ether ketone copolymers can have the following formula (I),
Therein, Ar1 contains 75 to 98 mol %, preferably 78 to 97 mol %, of 1,4-phenylene groups and 2 to 25 mol %, preferably 3 to 22 mol %, of X,Y-naphthylene groups. In the X,Y-naphthylene groups, X≠Y, X and Y independently of one another are an integer value of 1 to 10, and 2,7-naphthylene groups are excluded. The mol % values relate to the amount of substance of Ar1, wherein all Ar1 groups sum to 100 mol %. The constituent Ar2 contains 2,2′-bisphenylmethanone groups, 2,4′-bisphenylmethanone groups, 3,3′-bisphenylmethanone group, 4,4′-bisphenylmethanone groups, or mixtures thereof, preferably 4,4′-bisphenylmethanone groups. The index n is 10 to 10000. The copolymers have a reduced melting point and are suitable for producing three-dimensional objects in powder bed fusion processes.
C08G 65/40 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives derived from phenols from phenols and other compounds
A process for preparing 3-methylthiopropionaldehyde, by a) providing a liquid stream with methyl mercaptan and/or the hemi thioacetal formed from 3-methylthiopropionaldehyde and methyl mercaptan; b) providing an acrolein with a vapor stream, where the major part of the vapor stream is acrolein, and the pressure of the vapor stream is lower than atmospheric pressure; c) introducing the liquid stream with methyl mercaptan and/or the hemi thioacetal formed from 3-methylthiopropionaldehyde and methyl mercaptan of a) and the acrolein with a vapor stream of b) into a reaction unit with a vapor-liquid mixing device, and d) reacting acrolein with methyl mercaptan and/or the hemi thioacetal formed from 3-methylthiopropionaldehyde and methyl mercaptan in the reaction unit of c) to give a 3-metyhlthiopropionaldehyde product mixture.
The present invention relates to a process for producing alcohols by hydrogenation of C13 aldehydes. The process according to the invention is performed in two consecutive hydrogenation stages, wherein the first hydrogenation stage employs an activated metal catalyst based on a nickel metal foam and the second stage employs a supported catalyst containing a catalytically active component from the group consisting of nickel, copper, chromium and mixtures thereof.
C07C 29/141 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group of C=O containing groups, e.g. —COOH of a —CHO group with hydrogen or hydrogen-containing gases
The present invention relates to a process for producing alcohols by hydrogenation of C4 to C20 aldehydes. The process according to the invention is performed in two consecutive hydrogenation stages, wherein the first hydrogenation stage employs an activated metal catalyst based on a nickel metal foam and the second stage employs a supported catalyst containing a catalytically active component from the group consisting of nickel, copper, chromium and mixtures thereof.
C07C 29/141 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group of C=O containing groups, e.g. —COOH of a —CHO group with hydrogen or hydrogen-containing gases
A coated composition for feeding a ruminant may include: (A) a core of a biologically active ingredient selected from (A-i) amino acids, N-acylamino acids, N-guanylamino acids, and/or salts thereof and/or 2-hydroxy-4-(methyl)butyric acid calcium salt; (A-ii) proteins; (A-iii) peptides; (A-iv) carbohydrates; (A-v) vitamins, vitamin A (acetate or palmitate), B, D2, D3, E, thiamine (HCl), riboflavin, nicotinic acid (amide), calcium pantothenate, choline pantothenate, pyridoxine hydrochloride, choline chloride, cyano-cobalamin, biotin, folic acid, and p-aminobenzoic acid; (A-vi) probiotic microorganisms; (A-vii) prebiotic foods; (A-viii) choline and salts thereof; (A-ix) polyunsaturated fatty acids, and salts thereof; and x) any combination of (A-i) to (A-ix); and (B) a coating, encapsulating the core, constituting 1 to 15% of total coated composition weight and including 85 to 95% wt./wt. of a film-forming agent, which is triethyl citrate, and 5 to 15% wt./wt. of an additive selected from an acetic ester of monoglycerides and triethyl citrate.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
A61J 3/07 - Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
A61K 31/14 - Quaternary ammonium compounds, e.g. edrophonium, choline
A61K 31/4188 - 1,3-Diazoles condensed with heterocyclic ring systems, e.g. biotin, sorbinil
A61K 31/519 - Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
A61K 31/592 - 9,10-Secoergostane derivatives, e.g. ergocalciferol, vitamin D2
A61K 31/593 - 9,10-Secocholestane derivatives, e.g. cholecalciferol, vitamin D3
A thermoplastic component may include a matrix component (A) and a filler component (B). The matrix component (A) may include a polyetheretherketone and the filler component (B) may include inorganic particles and carbon-containing particles. The overall composition may include equal or different portions, as filler component (B), of hydrophobic silicon dioxide, carbon fibres, titanium dioxide particles, graphite particles, and a particulate lubricant selected from divalent metallic sulfides and alkaline earth metal sulfates.
A facility and a process with four membrane separation units, where the second separation unit separates the retentate of the first unit, the third separation unit separates the permeate of the first unit, the fourth separation unit separates the retentate of the third unit, the permeate of the second unit and the retentate of the fourth unit are recycled to the feed to the first unit, the permeate of the fourth unit is passed to a methane oxidation unit and the permeate of the third unit is discharged to the atmosphere allows separating methane and carbon dioxide from a gas stream, providing a methane rich stream with the retentate of the second unit at a high methane yield and adhering to low limits for methane discharge to the atmosphere with a small size methane oxidation unit.
B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
B01D 53/30 - Controlling by gas-analysis apparatus
18.
PROCESS FOR HYDROGENATION OF C9 ALDEHYDES IN AT LEAST TWO HYDROGENATION STAGES
The present invention relates to a process for producing alcohols by hydrogenation of C9 aldehydes. The process according to the invention is performed in two consecutive hydrogenation stages, wherein the first hydrogenation stage employs an activated metal catalyst based on a nickel metal foam and the second stage employs a supported catalyst containing a catalytically active component from the group consisting of nickel, copper, chromium and mixtures thereof.
C07C 29/141 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group of C=O containing groups, e.g. —COOH of a —CHO group with hydrogen or hydrogen-containing gases
Modified silicas, having the following physicochemical parameters: a CTABmod of <200 m2/g, a BETMP of 50-500 m2/g, a CTABmod-BETMP of <0 m2/g, a carbon content of >0.5% by weight, a modemod from CPS particle size determination of >50 nm, a d75mod from CPS particle size determination of 20-150 nm, a Rmin from Hg pore size determination, pressurized of <10 nm, and a sulfur content of ≤1.50% by weight.
A microorganism is transformed to be capable of producing guanidinoacetic acid (GAA). A method can be used for the fermentative production of GAA using such a microorganism. A corresponding method can be used for the fermentative production of creatine.
A process for preparing polysulfane silanes of formula (I):
A process for preparing polysulfane silanes of formula (I):
(R1)3-mR2mSi—R3—Sx—R3—SiR2m(OR1)3-m (I),
A process for preparing polysulfane silanes of formula (I):
(R1)3-mR2mSi—R3—Sx—R3—SiR2m(OR1)3-m (I),
may include reacting at least one halosilane of formula (II):
A process for preparing polysulfane silanes of formula (I):
(R1)3-mR2mSi—R3—Sx—R3—SiR2m(OR1)3-m (I),
may include reacting at least one halosilane of formula (II):
(R1)3-mR2mSi—R3-Hal (II),
A process for preparing polysulfane silanes of formula (I):
(R1)3-mR2mSi—R3—Sx—R3—SiR2m(OR1)3-m (I),
may include reacting at least one halosilane of formula (II):
(R1)3-mR2mSi—R3-Hal (II),
with M(SH)y and/or MzS and sulfur, in the presence of a phase transfer catalyst, a base and an aqueous phase, wherein the phase transfer catalyst is an alkylguanidinium catalyst of the formula (III):
A process for preparing polysulfane silanes of formula (I):
(R1)3-mR2mSi—R3—Sx—R3—SiR2m(OR1)3-m (I),
may include reacting at least one halosilane of formula (II):
(R1)3-mR2mSi—R3-Hal (II),
with M(SH)y and/or MzS and sulfur, in the presence of a phase transfer catalyst, a base and an aqueous phase, wherein the phase transfer catalyst is an alkylguanidinium catalyst of the formula (III):
A process for preparing polysulfane silanes of formula (I):
(R1)3-mR2mSi—R3—Sx—R3—SiR2m(OR1)3-m (I),
may include reacting at least one halosilane of formula (II):
(R1)3-mR2mSi—R3-Hal (II),
with M(SH)y and/or MzS and sulfur, in the presence of a phase transfer catalyst, a base and an aqueous phase, wherein the phase transfer catalyst is an alkylguanidinium catalyst of the formula (III):
and at least two groups of R4, R5, R6, R7, and R8 are —(CH2)2CH3, —CH2CH3, or —CH3.
A process can be used for the functionalization of graphene material by mixing graphene material with at least one silane. The functionalized graphene material is useful, for example, in thermoplastics.
A composition contains at least one lipase selected from SEQ ID NO: 1 and its respective at least 60%, preferably at least 80%, more preferably at least 90%, especially preferably at least 95%, 98%, or 99%, homologues at the amino acid level; at least one biosurfactant; and optionally, at least one non-bio surfactant. The composition can be used to to remove fat and/or oil-containing stains from a surface.
A polyester is useful as a high viscosity base fluid. A method for its preparation involves isomerizing an alpha-olefin, epoxidizing an internal olefin, reacting an internal epoxide, and isolating the polyester. Lubricant compositions can contain such polyesters and the compositions are useful as automatic transmission fluids, manual transmission fluids, continuously variable transmission fluids, gear oil formulations, industrial gear oil formulations, axle fluid formulations, dual clutch transmission fluids, dedicated hybrid transmission fluids, or as hydraulic oils.
Disclosed herein is an epoxy-amine adduct comprising a reaction product of a heterocyclic amine comprising a reaction product of a polyethylene polyamine having 3 to 10 nitrogen atoms and an aldehyde having 1 to 8 carbon atoms; and at least one epoxide having one or more epoxy groups, wherein the heterocyclic amine has at least two nitrogen atoms in at least one ring, and the epoxide is essentially free of polyether modification. A curing agent comprising the epoxy-amine adduct and a method for preparing the epoxy-amine adduct are provided.
C08G 59/18 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
26.
DNA-METHYLATION-BASED QUALITY CONTROL OF THE ORIGIN OF ORGANISMS
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS (Germany)
Inventor
Tönges, Sina
Lyko, Frank
Venkatesh, Geetha
Andriantsoa, Ranja
Gatzmann, Fanny
Böhl, Florian
Kappel, Andreas
Igwe, Emeka Ignatius
Thiemann, Frank
Abstract
The invention pertains to a method for the identification of the geographic origin of an individual test subject or of an individual group of test subjects, the method comprising the comparison of a test methylation profile obtained from genomic material of the individual test subject or of the individual group of test subjects with one or more predetermined reference methylation profiles each being specific for a distinct geographic origin.
A polyester is useful as a high viscosity base fluid. A method for its preparation involves epoxidizing an alpha-olefin, reacting the alpha-epoxide or diol with a saturated linear aliphatic dicarboxylic acid, and isolating the polyester. Lubricant compositions can contain such polyesters and the compositions are useful as automatic transmission fluids, manual transmission fluids, continuously variable transmission fluids, gear oil formulations, industrial gear oil formulations, axle fluid formulations, dual clutch transmission fluids, dedicated hybrid transmission fluids, or as hydraulic oils.
A process can be used for preparing aldehydes from C2 to C20 olefins with a subsequent thermal separation for removal of the aldehyde formed. The process involves a membrane separation, which is preceded by performance of a gas exchange by which the proportion of the partial pressure represented by carbon monoxide or hydrogen is increased in order to reduce catalyst losses.
An aqueous emulsion contains a copolymer having three components: a) to c). Component a) has at least one biuret or isocyanurate substructure. Component b) is selected from polysiloxanes and polyhydrocarbons, preferably polysiloxanes. Component c) contains a hydrocarbon which is different from component b) and has at least 6 carbon atoms and not more than 3 heteroatoms selected from N, O, and S. Component b) is joined to 2 different or identical components a) via at least two positions.
C08G 18/28 - Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
D06M 15/227 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds of hydrocarbons, or reaction products thereof, e.g. afterhalogenated or sulfochlorinated
D06M 15/564 - Polyureas, polyurethanes or other polymers having ureide or urethane links; Precondensation products forming them
D06M 15/653 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds containing silicon in the main chain modified by isocyanate compounds
32.
DIMETHYL SULFONE FOR TREATMENT OF CHRONICALLY HEAT STRESSED POULTRY
Dimethyl sulfone may be used in the treatment of heat stress in poultry by oral administration, wherein the dimethyl sulfone is administered to chronically heat stressed poultry. The poultry may be exposed to a temperature of more than 27° C., or at least 30° C., optionally for at least 5 hours a day. The poultry may be exposed to a relative air humidity of at least 40% on average. The dimethyl sulfone is administered to poultry in a starter, grower, and/or finisher phase.
A microorganism is transformed to be capable of producing guanidinoacetic acid (GAA). A method can be used for the fermentative production of GAA using such a microorganism. A corresponding method can be used for the fermentative production of creatine.
A pharmaceutical composition contains at least one methacrylic copolymer having units derived from methacrylamide; at least one pharmaceutically active ingredient; at least one lipid component; and at least one surfactant. The pharmaceutical composition can be used as a medicament. A method can be used to prepare a solid self-nanoemulsifying drug delivery system using the different compounds of the pharmaceutical composition.
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 31/635 - Compounds containing para-N-benzene- sulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonohydrazide having a heterocyclic ring, e.g. sulfadiazine
A61K 31/216 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
A61K 31/536 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
C07C 67/40 - Preparation of carboxylic acid esters by oxidation of groups which are precursors for the acid moiety of the ester by oxidation of primary alcohols
A computer-implemented method of systematically controlling and managing a production cycle of a livestock farm housing a population of animals, the method comprising (a) obtaining real-time data by a plurality of, sensors and/or manual or machine-based measurement and evaluation devices, including a set of farm condition parameters, (b) establishing statistical correlations of animal status parameters and process parameters with the animal performance parameters; (c) calculating and automatically adjusting, depending on the farm condition parameters obtained in (a) and on the statistical correlations identified in (b), a set of data set points for farm operating parameters such that at least one of a selected one of the animal performance parameters is optimized; and (d) repeatedly conducting (a) to (c) until finishing the production cycle. A system for systematically controlling and managing a production cycle of a livestock farm housing a population of animals.
A method for the electrochemical preparation of alkanedicarboxylic acids involves a ring-opening oxidation with a doped Ni(O)OH foam electrode in an aqueous alkaline solution.
Compositions containing at least one compound of Formula (I) are useful as carriers for at least one active ingredient.
Compositions containing at least one compound of Formula (I) are useful as carriers for at least one active ingredient.
Compositions containing at least one compound of Formula (I) are useful as carriers for at least one active ingredient.
In Formula (I), R1 is a monovalent aliphatic radical having 1 to 22 carbon atoms; R2 is in each case independently a hydrogen radical or a methyl radical; n is a number from 1 to 300; and at least one R2 radical is a methyl radical. Methods can be used for storing the active ingredient in the carrier and active ingredient compositions contain both the carrier and the active ingredient. The active ingredient compositions can be used for the treatment of plants, seed, and soils; and can be used as a biostimulant, a probiotic food supplement, a probiotic animal feed additive, a plant protection product, or a probiotic medicament. The active ingredient compositions can be used in corresponding methods of treating plants, seed, or soils.
A composition may include at least one oligopeptide having solely alpha-peptide-bonds with one amino acid being cysteine (Cys), and free cysteine. A culture medium and may be used for culturing cells, preferably plant cells, animal cells, or mammalian cells, and a cell culture product may be manufactured using such a method.
A novel methacrylic copolymer contains units derived from at least one alkyl methacrylate and methacrylamide. The units derived from methacrylamide are present in at least 34 wt.-%, based on the total weight of the methacrylic copolymer. A method can be used for preparing these novel methacylic copolymers. Pharmaceutical compositions, nutraceutical compositions, coated pharmaceutical or nutraceutical dosage forms, as well as nano- or microparticles can contain the methacrylic copolymer. The methacrylic copolymer can be used as a coating, as a carrier, and as a matrix for an amorphous solid dispersion.
The present invention relates to a computer-implemented method for predicting a property value of interest in a sample investigated by infrared spectroscopy. The method aims at generating a calibration function. To this end, a set of calibration samples is selected, whereby outliers are identified and removed from the set of calibration samples. Outliers are determined using principal component analysis and singular value decomposition. The threshold value separating outliers from the remaining samples is calculated on the basis of a predetermined formulae. The threshold value may also be increased stepwise in order to dynamically set the threshold value, which is preferable for spectroscopic devices not operated under laboratory conditions.
G01N 21/27 - Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 21/359 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
G06F 18/214 - Generating training patterns; Bootstrap methods, e.g. bagging or boosting
G16C 60/00 - Computational materials science, i.e. ICT specially adapted for investigating the physical or chemical properties of materials or phenomena associated with their design, synthesis, processing, characterisation or utilisation
G16C 20/20 - Identification of molecular entities, parts thereof or of chemical compositions
G16C 20/30 - Prediction of properties of chemical compounds, compositions or mixtures
43.
COMPOSITIONS COMPRISING RHAMNOLIPID, ALKYL POLYGLYCOSIDE AND ACYL LACTYLATE
A composition contains 2 to 6 parts by weight of at least one rhamnolipid, 1 to 4 parts by weight of at least one alkyl polyglycoside, and 1 to 3 parts by weight of at least one acyl lactylate.
A61Q 17/02 - Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
44.
Process for hydroformylation of olefins using Pt and bromine
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
49.
Pt-biphenyl-iodine complex and Pt-biphenyl-bromine complex
C07F 15/00 - Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
C07F 15/00 - Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
51.
PROCESS FOR PRODUCING CARBON MONOXIDE-CONTAINING STREAMS
A process for providing a carbon monoxide-containing stream involves a separation of synthesis gas into a hydrogen-rich gas stream and a carbon monoxide-rich gas stream containing carbon monoxide to an extent of 85% by volume or more. The separation is effected in an arrangement composed of three membrane separation stages. Prior to the performance of the membrane separation, the synthesis gas is pretreated for removal of secondary components present in the synthesis gas.
C01B 3/50 - Separation of hydrogen or hydrogen containing gases from gaseous mixtures, e.g. purification
B01D 53/22 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
C07C 51/14 - Preparation of carboxylic acids or their salts, halides, or anhydrides by reaction with carbon monoxide on a carbon-to-carbon unsaturated bond in organic compounds
52.
Pt-DPEphos-iodine complex and Pt-DPEphos-bromine complex
C07F 15/00 - Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
The present invention is directed to biodegradable cleaning compositions, in particular hard surface cleaning compositions, and their use. The compositions according to the invention comprise one or more biosurfactants(s), one or more sorbitan ester(s) and one or more further surfactant(s), which is/are neither a biosurfactant nor a sorbitan ester.
The present invention relates to. a bioreactor vessel (1) having an outer vessel wall (2) and a bottom (3), further comprising an integrated internal structure (4) providing at least two additional surfaces (4a), (4b) to the internal reactor space of said vessel, said internal structure (4) being spaced apart from said outer vessel wall (2), as well as to a process for growing biological cells using said bioreactor vessel.
A process is described for producing PU foams, especially rigid PU foams, based on foamable reaction mixtures containing polyisocyanates, compounds having reactive hydrogen atoms, blowing agents, foam stabilizers, and possibly further additives, wherein specific perfluoropolyethers are additionally used.
C08G 18/12 - Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step using two or more compounds having active hydrogen in the first polymerisation step
C08J 9/14 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
58.
METHOD FOR PRODUCING HIGHER LINEAR FATTY ACIDS OR ESTERS
The present invention relates to a method of producing linear fatty acids comprising 7 to 28 carbon atoms or esters thereof using a combined biotechnological and chemical method. In particular, the present invention relates to a method of producing dodecanoic acid (i.e. lauric acid), via higher alkanones, preferably 6-undecanone.
C07C 51/14 - Preparation of carboxylic acids or their salts, halides, or anhydrides by reaction with carbon monoxide on a carbon-to-carbon unsaturated bond in organic compounds
C07C 51/48 - Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
A novel process can be used for the preparation of polyalkyl (meth)acrylate polymers with improved compositional distribution, which leads to better producibility, solubility, and improved performance of the polymers in lubricant compositions, especially in engine oil formulations.
The invention relates to a rubber mixture comprising rubber and a liquid polybutadiene, liquid at a temperature of 20° C. and a pressure of 98.0665 kPa, wherein the liquid polybutadiene only consists of C— and H-atoms, and has an average molecular weight (Mw), determined by gel permeation chromatography as described in the description, of from 1500 to 5000 g/mol, to a process for preparing rubber articles by vulcanization using the inventive rubber mixtures as raw material, and to rubber articles obtained by this process.
The present invention relates to fiber polymer composite comprising polypropylene fibers and a matrix material, the matrix material being in direct contact with at least some of the fibers, characterized in that the matrix material comprises 50% to 100% by weight based on the whole matrix material of an amorphous propylene-rich poly-alpha-olefin, to a process for producing the fiber polymer composite, and to the use of the fiber polymer composite.
A process for producing an oligomerization catalyst includes hydrothermal treatment. An oligomerization catalyst produced by the process is useful for the oligomerization of C2 to C12 olefins.
A process for preparing aldehydes by a homogeneously catalyzed hydroformylation of C4 to C20 olefins involves withdrawing a biphasic stream (liquid/gaseous) and expanding in two stages. Before, between, or after the two stages, the liquid phase is cooled. Only after expansion and cooling is the homogeneously dissolved rhodium catalyst system separated from the residual stream in a three-stage removal.
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
64.
Curable condensation compounds based on alkoxy-functional polysiloxanes
Curable condensation compounds are obtainable by a reaction of non-end-equilibrated acetoxy group-bearing siloxanes with at least one alkoxy-functional polysiloxane, in the presence of a catalyst.
A process for preparing aldehydes by a homogeneously catalysed hydroformylation of C4 to C20 olefins involves withdrawing a biphasic stream (liquid/gaseous) and expanding in two stages. Before, between, or after the two stages, the liquid phase is cooled. Only after expansion and cooling is the homogeneously dissolved rhodium catalyst system separated from the residual stream.
C07C 45/50 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide by oxo-reactions
B01J 23/46 - Ruthenium, rhodium, osmium or iridium
C07C 45/62 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of C=O groups by hydrogenation of carbon-to-carbon double or triple bonds
A composition for use as antioxidant, where the composition has at least one polyunsaturated fatty acid component and at least one anthocyanin component. The polyunsaturated fatty acid component is an amino acid salt of the omega-3 fatty acids eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA). The anthocyanin component is cyanidin-3-glucoside, delphinidin-3-glucoside, malvidin-3-galactoside, peonidin-3-galactoside, or malvidin-3-glucoside. A method for treating a disease with the composition. A method of providing an antioxidant to a subject with the composition.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A23L 33/00 - Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
A61P 39/06 - Free radical scavengers or antioxidants
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A process can be used for preparing nano- or microparticles containing a carrier-polymer and a biologically active ingredient. The process is a solvent emulsion process involving an organic phase (OP) and an aqueous phase (AP) to form an emulsion. In the case of an oil-in-water emulsion (O/W), the organic phase (OP) contains the biologically active ingredient dissolved or dispersed therein. Alternatively, in the case of a water-in-oil emulsion (W1/O), the aqueous phase (AP) contains the biologically active ingredient dissolved or dispersed therein. The organic phase (OP) is saturated with the salt-containing aqueous phase (AP) and vice versa.
A61K 31/41 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
A61K 31/536 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
A61K 31/635 - Compounds containing para-N-benzene- sulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonohydrazide having a heterocyclic ring, e.g. sulfadiazine
A61K 31/045 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
A filter holder for liposome extrusion includes a housing having an inlet configured to receive a material to be extruded and an outlet, and a filter support member disposed within the housing between the inlet and the outlet. The filter support member includes an upstream side having a filter support surface configured to support a membrane filter assembly, a downstream side opposite the upstream side, and a plurality of passages extending through the filter support member from the filter support surface to the downstream side. The filter holder also includes an outlet cavity in fluid communication with the outlet, and the filter holder is configured such that the material to be extruded flows through the membrane filter assembly and into the outlet cavity via the plurality of passages before being discharged through the outlet.
A preparation comprising probiotic strains belonging to the genera Bacillus sp., Lactobacillus sp., optionally Pediococcus sp. as viable cells or cytoplasmic extract thereof, and proteases, wherein the strains can degrade peptide sequences of gliadins. The preparation can be used to produce gluten-free foods from gluten-containing cereals or to treat gluten-related disorders.
Polymer foams based on polyetherimides (PEI) or blends of polyetherimides and polyether ether ketone (PEEK) meet the legal requirements demanded by the aviation industry for aircraft interiors and for aircraft exteriors too.
Methods can be used for producing three-dimensional objects by powder bed fusion, using inks containing superparamagnetic particles and solvents. Sintering is performed by a magnetic field having a frequency of 50 kHz to 5 GHz.
A composition contains glycolipids and Methyl citrate (TEC). The TEC can assist in stabilizing a foam of a corresponding aqueous composition. A method can be used for preparing a corresponding formulation, preferably a cosmetical or pharmaceutical formulation, by providing the composition and diluting the composition. The pH of the composition may be adjusted during the dilution by adding an organic or inorganic base
The present invention relates generally to amine curing agents compositions useful in formulation additives, compositions comprising systems, resin formulations, and the use of these compositions in methods of making objects by additive manufacturing using 3D printing methodologies.
A process can be used for recovering 1-methoxy-2-propanol and 2-methoxy-1-propanol from an aqueous effluent stream by liquid-liquid-extraction, followed by extractive distillation, distillation of methoxypropanols from the extraction solvent, and distillative separation of the methoxypropanol isomers. Recovered extraction solvent is recycled to the extraction and extractive distillation. Heat transfer from recovered extraction solvent to the extract fed to the extractive distillation reduces energy demand of the process. A facility for this process contains a countercurrent extraction column, an extractive distillation column, a solvent recovery distillation column, an isomer separation distillation column, and a heat exchanger for transferring heat from recovered extraction solvent to the extract fed to the extractive distillation.
A process for making propene oxide involves reacting propene with hydrogen peroxide in the presence of methanol, a titanium zeolite epoxidation catalyst, and nitrogen containing compounds present in an amount of from 100 to 3000 mg/kg of hydrogen peroxide. Non-reacted propene is separated from the reaction mixture; the propene depleted reaction mixture Is continuously distilled in a distillation column providing an overhead product stream containing propene oxide and methanol and a bottoms product stream; and propene oxide is separated from the overhead product stream. An acid is added to the propane depleted reaction mixture and/or to the distillation column at the same level or above the feed point for the propene depleted reaction mixture and/or contacted to the feed to the distillation column to provide an apparent pH in the bottoms product stream of from 3 to 4.5, which reduces the nitrogen content of the separated propene oxide.
C07D 301/12 - Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with hydrogen peroxide or inorganic peroxides or peracids
C07D 303/04 - Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
An aqueous polymer dispersion is based on copolymers of alkyl (meth)acrylates having long side chains and unsaturated carboxylic acids. The aqueous polymer dispersion also contains at least one cosolvent and an emulsifier system containing at least one emulsifier from the group of sulfosuccinates.
Polymer foams based on polyetherimides (PEIs) fulfill the legal specifications demanded by the aviation industry for aircraft interiors. Specifically, the demands on fire characteristics, stability to media and mechanical properties constitute a great challenge here. According to related art, suitable polymer foams are produced as semi-finished products. Reprocessing to give shaped articles is uneconomic in terms of time and material exploitation, for example by virtue of large amounts of cutting waste. The material is suitable in principle and can be processed to give particle foam mouldings. These mouldings can be produced without reprocessing in short cycle times and, hence, economically. Furthermore, this gives rise to new means of functional integration, for example by direct incorporation of inserts etc. in the foam, and with regard to freedom in terms of design.
The present invention relates to a process for producing a solid, internally and externally blocked polyurethane curing agent based on a (cyclo)aliphatic polyisocyanate, in which, in the sequence of steps a) to d),
a) i) at least one internally blocked (cyclo)aliphatic polyisocyanate and
ii) at least one lactam and/or at least one aliphatic alcohol are dissolved in a solvent to produce a reaction mixture,
b) the reaction mixture is heated and reacted,
c) the reacted reaction mixture is cooled until product precipitates, and
d) liquid solvent and any unreacted dissolved reactants and precipitated product are mechanically separated from one another.
A monomer material for preparing a polymer electrolyte precursor composition capable to form an in-situ polymerized polymer electrolyte, which comprises, consists essentially of, or consists of A1) a first monomer and optionally A2) a second monomer. A polymer electrolyte precursor raw material composition, a polymer electrolyte precursor composition capable to form a polymer electrolyte comprising the monomer material, a polymer electrolyte and an electrochemical device are also provided.
C08F 224/00 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a heterocyclic ring containing oxygen
An aqueous polymer dispersion is based on alkyl (meth)acrylates having long side chains. The aqueous polymer dispersion also contains at least one cosolvent and an emulsifier system containing at least two emulsifiers from the group of sulfosuccinates.
C08F 220/18 - Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
C08K 5/41 - Compounds containing sulfur bound to oxygen
C08L 91/00 - Compositions of oils, fats or waxes; Compositions of derivatives thereof
C08J 3/11 - Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in organic liquids from solid polymers
A one-pot synthesis of polymerizable and acyclic urea (meth)acrylates, preferably mono(meth)acrylates, can be performed via in-situ synthesis of urea alcohols or amines followed by direct reaction with a (meth)acrylate reactive diluent. The urea alcohol/amine is obtained from isocyanates and alcohols, amines, or hydroxyamines. Subsequently, the reaction with the (meth)acrylate reactive diluent takes place and the urea (meth)acrylate is directly obtained either in solution with the reactive diluent, or as a pure material after removal of the reactive diluent.
C07C 273/18 - Preparation of urea or its derivatives, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
82.
POLYURETHANE INSULATING FOAMS AND PRODUCTION THEREOF
A process is described for producing PU foams, especially rigid PU foams, based on foamable reaction mixtures containing polyisocyanates, compounds having reactive hydrogen atoms, blowing agents, foam stabilizers, and possibly further additives, wherein polymer particles are additionally used, the average particle size of the polymer particles being <100 μm, preferably <70 μm, especially 5 to 50 μm.
C08G 18/09 - Processes comprising oligomerisation of isocyanates or isothiocyanates involving reaction of a part of the isocyanate or isothiocyanate groups with each other in the reaction mixture
C08J 9/14 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
A method for controlling a chemical process, by preparing methanol, hydrogen sulfide, methyl mercaptan, hydrocyanic acid, acrolein, 3-methylthiopropionaldehyde, 5-(2-methylmercaptoethyl)-hydantoin, methionine, a salt of methionine, and a derivative of methionine. The method includes providing a training set TS1, wherein TS1 is process values PV1 and process values PV2 being correlated to one another, and/or laboratory values LV1 and process values PV2 being correlated to one another. The method includes training a processing unit on the training set TS1 to identify a pattern of correlation between one or more measured process variables and at least one process variable. The method includes developing a calibration function CF1 for a calibrated soft sensor from the identified pattern of correlation and predicting at least one operating parameter for the chemical process as an approximation to LV1 and/or PV1. A system for controlling a chemical process.
B01D 53/14 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
B01D 53/34 - Chemical or biological purification of waste gases
G05B 19/4155 - Numerical control (NC), i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by programme execution, i.e. part programme or machine function execution, e.g. selection of a programme
84.
Halogermanides and methods for the preparation thereof
A process for ring hydrogenation of dialkyl terephthalates having C3- to C16-alkyl groups can be performed in a hydrogenation unit composed of two reaction units in series. In the process, a suitable process parameter in relation to the first reaction unit is adjusted so that a certain reaction conversion is achieved.
C07C 67/303 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
B01J 23/46 - Ruthenium, rhodium, osmium or iridium
B01J 21/06 - Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
A novel urea (meth)acrylate can be prepared by a process involving reacting a urea containing alcohol or amine with a (meth)acrylate, (meth)acryloyl chloride, (meth)acrylic acid, or (meth)acrylic anhydride. A binder composition includes at least one repeating unit derived from the urea (meth)acrylate. The binder composition can be used in adhesive and coating applications.
C07C 275/12 - Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by doubly-bound oxygen atoms
A process can be used for preparing a polymer coated hard-shell capsule, filled with a fill containing a biologically active ingredient. The hard-shell capsule contains a body and a cap, and in a closed state, the cap overlaps the body either in a pre-locked state or in a final-locked state. The material of the body and the cap contains an ethyl-, methyl-, or propyl-ether of cellulose, starch, or pullulan. The hard-shell capsule is coated with a coating layer that covers the hard-shell capsule in the pre-locked state. The coating layer contains one or more (meth)acrylate copolymers, where the coating layer is present in an amount of about 1 to 5.8 mg/cm2. The process involves providing the polymer-coated hard-shell capsule in the pre-locked state to a capsule-filling machine, separating the body and the cap, filling the body with the fill, and rejoining the body and the cap in the final-locked state.
A silane composition contains at least one iminosilane and at least one antioxidant. The at least one antioxidant is a sterically hindered phenol. A process can be used for the production of the silane composition.
A composite body comprising a porous layer (1) made from oxide particles connected to one another and partially to a substrate, containing at least one oxide of the elements Al, Zr, Ti or Si, and comprising a further porous layer (2) at least on one side, having oxide particles connected to one another and partially to the layer (1) and containing at least one oxide of the elements Al, Zr, Ti or Si, wherein the oxide particles in the layer (1) have a greater average particle size (d50 is 0.5 to 4 μm) than the oxide particles in the layer (2) (d50 is 0.015 to 0.15 μm), characterised in that a polymer coating (PB) is provided on or above the layer (2), containing one or more polysiloxanes. A method for producing corresponding composite bodies and to the use thereof.
B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
Fumed silica powder, surface treated with a surface treatment agent selected from the group consisting of organosilanes, silazanes, acyclic polysiloxanes, cyclic polysiloxanes, and mixtures thereof, wherein the powder has:
a) a number of silanol groups relative to BET surface area dSiOH of at least 0.85 SiOH/nm2, as determined by reaction with lithium aluminium hydride;
b) a methanol wettability of more than 40% by volume of methanol in methanol-water mixture;
c) a tamped density of not more than 200 g/L.
The invention pertains to an in vitro method for predicting the chronological age of healthy Galliformes, the method comprising the steps of: (a.) obtaining genomic DNA from biological sample material deriving from the Galliformes subject or from the Galliformes population to be tested, (b.) determining the methylation level of a set of specific CpG sites in the genomic Galliformes DNA obtained in step (a.), and (c.) comparing the methylation levels of these CpG sites in the genomic Galliformes DNA from the sample to be tested with the methylation level of the same CpG sites from an age-correlated reference sample, thereby establishing the epigenetic age and predicting the chronological age of the subject or of the population to be tested; wherein for the set of specific CpG sites in step (b) the impact of genetic polymorphisms is eliminated by excluding CpG sites associated with single nucleotide polymorphisms, and the impact of sex-specific methylation differences on sex chromosomes is eliminated by excluding all CpG sites located on sex chromosomes.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
92.
A METHOD OF ESTABLISHING A WHOLE-TISSUE EPIGENETIC CLOCK FOR AVIAN SPECIES
A computer-implemented method of establishing an epigenetic clock for an avian species including: (a) identifying and determining methylation levels of specific CpG sites within a genomic DNA obtained from a plurality of different biological sample materials deriving from the avian species and representing specific time points within a chronological lifespan of the avian species, (b) excluding all CpG sites associated with single nucleotide polymorphisms (SNPs) from the CpG sites identified in (a), (c) excluding all CpG sites located on sex chromosomes from the CpG sites obtained in (b), (d) performing a tissue-specific normalization for the CpG sites obtained in (c), and (e) correlating the CpG methylation levels of the CpG sites obtained in (d) with chronological age with a penalized regression model.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
93.
COMPOSITIONS COMPRISING CYANIDIN-3-GALACTOSIDE FOR USE AS VASORELAXANT
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 36/45 - Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
The invention concerns new Bacillus strains which are able to degrade effectively inorganic nitrogen compounds and are further able to inhibit the growth of pathogens of aquatic animals.
A process can be used for the enzymatic preparation of sugar esters and/or sugar alcohol esters. Mixture compositions contain the sugar esters and/or sugar alcohol esters.
A dosage form contains a biologically active ingredient for treating or preventing a disease in the animal or human body, where treatment or prevention requires release of 50% or more of the biologically active ingredient in the small intestine within the pH range from 3 to 5.5. The dosage form contains: a) a core, containing the biologically active ingredient; b) an intermediate coating layer (ICL) onto or above the core, containing an alkaline agent; and c) an enteric coating layer (ECL) onto or above the ICL, containing an enteric polymer. The relation of alkaline agent to enteric polymer is 5 to 95% when calculated by the formula:
A dosage form contains a biologically active ingredient for treating or preventing a disease in the animal or human body, where treatment or prevention requires release of 50% or more of the biologically active ingredient in the small intestine within the pH range from 3 to 5.5. The dosage form contains: a) a core, containing the biologically active ingredient; b) an intermediate coating layer (ICL) onto or above the core, containing an alkaline agent; and c) an enteric coating layer (ECL) onto or above the ICL, containing an enteric polymer. The relation of alkaline agent to enteric polymer is 5 to 95% when calculated by the formula:
quantity
of
alkaline
agent
in
grams
in
the
ICL
×
100
(
quantity
of
alkaline
agent
in
grams
in
the
ICL
+
quantity
of
enteric
polymer
in
grams
in
the
ECL
)
.
The
ICL
has
a
thickness
of
about
22
μ
m
or
more
.
A61K 31/4439 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
The invention provides a method of establishing a chicken methylation clock comprising: (a) determining the methylation ratio and the read coverage of the genomic CpG sites of an age-correlated training sample of a specific chicken tissue; (b) defining a set of CpG sites having reliable methylation ratios in all training samples of step (a) using a cutoff value; and (c) performing a penalized regression using the methylation ratios of step (b) as input and the age correlated to the training sample as dependent variable, by applying a penalized regression model; thereby obtaining a set of CpG sites with corresponding weighting factors and intercept of the linear model equation as parameters defining the chicken methylation clock.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
98.
NOVEL HALOGERMANIDES AND METHODS FOR THE PREPARATION THEREOF
A trichlorogermanide of formula (I): [R4N]/[R4P]Cl[GeCl3] (I), where R is Me, Et, iPr, nBu, or Ph, tris(trichlorosilyl)germanide of formula (II): [R4N]/[R4P][Ge(SiCl3)3] (II), where R is Me, Et, iPr, nBu, or Ph, a tris(trichlorosilyl)germanide adduct of GaCl3 of formula (III): [Ph4P][Ge(SiCl3)3*GaCl3], and a tris(trichlorosilyl)germanide adduct of BBr3 of formula (IV): [Ph4P][Ge(SiCl3)3*BBr3]. Also, methods for preparing the trichlorogermanides of formula (I), the tris(trichlorosilyl)germanide of formula (II), the tris(trichlorosilyl)germanide adduct of BBr3 of formula (IV).
An electrode for a lithium battery contains a metal layer coated with a coating layer containing an organic binder and a metal compound. The metal compound is selected from aluminium oxide, silicon dioxide, zirconium oxide, mixed oxides including zirconium, mixed oxides including aluminium, lithium zirconium phosphate, and mixtures thereof. The metal compound is made of aggregates of primary particles with a number mean primary particle size d50 of 5 nm-100 nm, obtained by a pyrogenic process. The weight ratio of the metal compound to the organic binder in the coating layer is from 0.1 to 10.
H01M 4/58 - Selection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
H01M 4/36 - Selection of substances as active materials, active masses, active liquids
H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
100.
Method for the energy-efficient production of sodium and potassium alcoholates
A method can be used for producing alkali metal alcoholates in counter flow by reactive rectification. The alkali metal is selected from sodium and potassium. In a first part of the method, the alcohol is converted in counter flow with the respective alkali metal hydroxide. In a second part of the method, the mixture of alcohol and water obtained is separated in a rectification column, and the alcoholic vapour arising is condensed, as a result of which the temperature thereof increases. The energy dissipated during cooling of the condensed vapour is then used in the first part of the method. This permits an energy-efficient production of the alkali metal alcoholates concerned.
patents
