01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
Chromatography chemicals; releasing agents [chemical];
chemicals used in the refining of hydrocarbons; chemical
substances for removing impurities from gases; chemical
cleaning agents for use in industrial manufacturing
processes; chemical substances, chemical materials and
chemical preparations and natural elements, namely spinels
[chemical products], spinels [oxidic minerals], extraction
chemicals; titanium oxides, lithium oxides, lithium
phosphates [chemicals]; chemical products for the production
of catalysts; salts for industrial purposes; catalysts;
biochemical and chemical catalysts; catalysts for refining
hydrocarbons; chemical catalysts for use in synthesis and
olefin purification; cracking catalysts for use in the
petroleum industry; catalysts for cracking hydrocarbons;
catalyst supports; catalyst supports made from inorganic
oxides; catalysts for use in industrial processes; chemical
adsorbents; chemical adsorbents for direct lithium
extraction; ion exchangers [chemicals]; synthetic resins in
the form of ion exchangers; oxides; oxides of metal;
modified metal oxides for industrial purposes; bauxite;
aluminum oxides [aluminum oxide]; aluminum oxides [aluminum
oxide] for adsorption; modified aluminum oxides for
adsorption; aluminium oxide; catalysts for the production of
plastics, rubber and polymers; catalysts for the petroleum
processing industry; petroleum dispersants; catalysts for
use in the production of rubber; catalysts for oxidation
treatment; catalysts for use in the production of plastics;
adsorbents; active chemical ingredients; oxidising
preparations; metal oxide powder for industrial purposes;
non-metal oxides.
The present invention concerns a method for treating the surface of glass, a substrate comprising a glass surface treating with the inventive method and the use of the substrate.
C03C 17/00 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating
C03C 17/30 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with organic material with silicon-containing compounds
C03C 17/34 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions
4.
COMPOSITION AND METHOD FOR TREATING THE SURFACE OF GLASS
The present invention relates to a composition and a method for treating at least one glass surface, preferably the surface of a glass container such as a glass bottle. The present invention further concerns a substrate comprising least one layer obtained by treating at least one glass surface thereof with the composition according to the invention.
C03C 17/00 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating
C03C 17/30 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with organic material with silicon-containing compounds
C03C 17/34 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions
5.
ENZYMATIC METHOD FOR PRODUCING L-GLUFOSINATE AND ITS PHOSPHOESTERS
An enzymatically catalyzed method for producing L-glufosinate or a phosphoester of L-glufosinate can be performed. An activated L-homoserine HA is reacted with a substrate S selected from methylphosphinic acid and the esters of methylphosphinic acid. The method makes accessible new substrates in the enzymatic production of L-glufosinate and its phosphoesters.
The invention relates to catalytically active heating elements, and to the production and use thereof in the production of hydrogen cyanide (HCN). The problem addressed by the invention is that of providing thermally stable and catalytically active heating elements with which a BMA process can be simultaneously electrically heated and chemically catalysed. In particular, the heating elements should be thermally and mechanically stable in continuous industrial operation and retain their catalytic activity. The heating element according to the invention has a layered structure (A, B, C) formed from (A) silicon carbide (SiC), (B) aluminium nitride (AlN) and (C) platinum (Pt). The silicon carbide (SiC) serves as an electric heating resistor. The platinum (Pt) serves as catalyst. Aluminium nitride (AlN) is arranged as a protective layer between platinum (Pt) and silicon carbide (SiC). It prevents platinum (Pt) and silicon carbide (SiC) from alloying during ongoing operation.
H05B 3/14 - Heating elements characterised by the composition or nature of the materials or by the arrangement of the conductor characterised by the composition or nature of the conductive material the material being non-metallic
H05B 3/42 - Heating elements having the shape of rods or tubes non-flexible
7.
BACILLUS SUBTILIS STRAIN WITH POSITIVE INFLUENCE ON NEURODEGENERATIVE DISEASES SUCH AS ALZHEIMER'S DISEASE
C12N 1/00 - Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
8.
A COMPUTER-IMPLEMENTED METHOD, A COMPUTER PROGRAM AND A COMPUTER FOR GENERATING A DIGITAL TWIN FOR A CHEMICAL PROCESS OR AN APPARATUS OR A SYSTEM OF A CHEMICAL PLANT
The invention concerns a computer-implemented method for generating a digital twin (20) for a chemical process or an apparatus or a system of a chemical plant, in particular for substance synthesis and/or substance separation, the method comprising the steps of: a) Inputting a plurality of boundary conditions (1) to a computational model (2), the computational model (2) comprising a system of equations, wherein each boundary condition (1) comprises a plurality of parameter values (4) respectively, b) Inputting initial conditions for solving the system of equations, c) Solving the system of equations using each of the boundary conditions (1) to provide a corresponding simulation result, respectively, in a simulation step, wherein a single one of the parameter values (4) of a respective boundary condition (1) is changed from one simulation step to the next simulation step, while the other parameter values (4) belonging to the respective boundary condition remain unchanged, and d) Providing the digital twin (20) as a set of data points obtained from the simulation steps. The invention also concerns a computer program and a computer (55) for generating a digital twin for a chemical process or an apparatus or a system of a chemical plant, in particular for substance synthesis and/or substance separation.
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
G06F 30/17 - Mechanical parametric or variational design
G06F 30/20 - Design optimisation, verification or simulation
G06F 111/06 - Multi-objective optimisation, e.g. Pareto optimisation using simulated annealing [SA], ant colony algorithms or genetic algorithms [GA]
G06F 111/18 - ELECTRIC DIGITAL DATA PROCESSING - Details relating to CAD techniques using virtual or augmented reality
9.
DILUTION-STABLE AQUEOUS COMPOSITIONS FOR THE MASS HYDROPHOBIZATION OF MINERAL BUILDING MATERIALS
Dilution-stable compositions are useful for the mass hydrophobization of mineral building materials. The compositions contain at least one organosiloxane (A), at least one emulsifier (B), and water. The organosiloxane (A) has SiC-bonded C2-C6 alkyl radicals and SiC-bonded C7-C18 alkyl radicals. Processes can be used for preparing the organosiloxane (A). Hydraulically setting compositions contain the organosiloxane (A).
C04B 28/02 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
C04B 40/00 - Processes, in general, for influencing or modifying the properties of mortars, concrete or artificial stone compositions, e.g. their setting or hardening ability
C08G 77/18 - Polysiloxanes containing silicon bound to oxygen-containing groups to alkoxy or aryloxy groups
10.
FUMED SILICA POWDER WITH REDUCED SILANOL GROUP DENSITY
Process for producing fumed silica powder with a decreased silanol group density, comprising subjecting a fumed surface untreated silica powder with a silanol density dSiOH of at least 1.2 SiOH/nm2 and a particle size d90 of not more than 10 μm, to thermal treatment at a temperature of 350° C. to 1250° C. for 5 min to 5 h, wherein the temperature and the duration of the thermal treatment are chosen so that dSiOH of the silica is decreased by 10%-70% relative to dSiOH of the employed thermally untreated silica, wherein the thermal treatment is carried out while the fumed silica powder is in motion, followed by optional surface treatment. Surface unmodified and modified fumed silica powders obtained by this process and the use thereof.
A defoamer composition is provided. It comprises I) an oil phase, II) a water phase, III) at least one O/W emulsifier, and IV) at least one W/O emulsifier as co-emulsifier wherein the amount of the water phase is 20-90 wt. %, preferably 60-85 wt. % based on the total weight of the composition, characterized in that the oil phase is an oil-in-oil emulsion comprising A) at least one or more vegetable oil as component A, B) at least one or more polyether ester as component B and C) at least one or more polyether-modified polysiloxane, and optional D) at least one or more hydrophobic particle as component D.
The present invention relates to a defoamer composition comprising I) an oil phase, II) a water phase, III) at least one 0/W emulsifier, and IV) at least one W/0 emulsifier as co-emulsifier wherein the amount of the water phase is 20 - 90 wt.%, preferably 60 - 85 wt.% based on the total weight of the composition, characterized in that the oil phase is an oil-in- oil emulsion comprising A) at least one or more vegetable oil as component A, B) at least one or more polyether ester as component B and C) at least one or more polyether-modified polysiloxane, and optional D) at least one or more hydrophobic particle as component D.
Tetraisopentyl esters of butanetetracarboxylic acid are useful as plasticizers or as part of a plasticizer composition for polymers. A process for the production thereof, plasticizer compositions containing the tetraisopentyl esters of butanetetracarboxylic acid, and plastics compositions containing the tetraisopentyl esters of butanetetracarboxylic acid are also provided.
C08L 27/06 - Homopolymers or copolymers of vinyl chloride
C07C 67/02 - Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification
C07C 67/08 - Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
14.
TETRAISOPENTYL ESTERS OF BUTANETETRACARBOXYLIC ACID, PRODUCTION THEREOF AND USE THEREOF AS PLASTICIZERS
Tetraisopentyl esters of butanetetracarboxylic acid are useful as plasticizers or as part of a plasticizer composition for polymers. A process for the production thereof, plasticizer compositions containing the tetraisopentyl esters of butanetetracarboxylic acid, and plastics compositions containing the tetraisopentyl esters of butanetetracarboxylic acid are also provided.
C08K 5/11 - Esters; Ether-esters of acyclic polycarboxylic acids
C07C 67/08 - Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
C07C 69/34 - Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
C08K 5/12 - Esters; Ether-esters of cyclic polycarboxylic acids
C08L 27/06 - Homopolymers or copolymers of vinyl chloride
15.
PROBIOTIC COMPOSITION FOR THE TREATMENT OF MALNUTRITION
This invention concerns the use of a probiotic composition comprising the probiotic strains Lactobacillus plantarum (Lactiplantibacillus plantarum) DSM 33363, Lactobacillus plantarum (Lactiplantibacillus plantarum) DSM 33364, Lactobacillus paracasei (Lacticaseibacillus paracasei) DSM 33373, Lactobacillus reuteri (Limosilactobacillus reuteri) DSM 33374, Bacillus megaterium (Priestia megaterium) DSM 33300, Bacillus pumilus DSM 33297, Bacillus pumilus DSM 33355 (the "Pro- nutrient" consortium), for treating and preventing malnutrition of humans and animals by increasing the nutritional value of cereal-based foodstuffs, derived from wheat in particular, through increasing the bioavailability of essential micronutrients and amino acids contained in these foodstuffs.
The invention relates to a method for producing SiOC-linked, linear polydialkylsiloxane-polyoxyalkylene block copolymers having repeating (AB) units, comprising the reaction of a linear, α,ω-(SiH)-functional polydialkylsiloxane (a) with a linear, α,ω-(OH)-functional polyoxyalkylene (b), using one or more compounds of elements of the third main group and/or third subgroup as catalyst (c), the two reactants (a) and (b) being preferably reacted in equimolar amounts and with controlled hydrogen formation until quantitative SiH conversion.
The current invention concerns preparations comprising the probiotic strain Lactobacillus plantarum (Lactiplantibacillus plantarum) DSM 33363 alone and in combination with Lactobacillus plantarum (Lactiplantibacillus plantarum) DSM 33364, Lactobacillus paracasei (Lacticaseibacillus paracasei) DSM 33373, Lactobacillus reuteri (Limosilactobacillus reuteri) DSM 33374, Bacillus megaterium (Priestia megaterium) DSM 33300, Bacillus pumilus DSM 33297, and Bacillus pumilus DSM 33355 as viable cells or cytoplasmic extract thereof and their use for the prevention and treatment of IBS as well as FODMAP intolerance.
The present invention is related to a plastic packaging material, the material comprising: - a first label readable by an end-user, wherein the first label is visible to the end-user and distinct for packaging material that is recyclable; and - a second label readable by at least one industrial waste sorting machine, wherein the second label comprises information on the material origin, type and/or use, and wherein the second label is at least one up-conversion based florescent marker that is invisible to the end-user.
The invention relates to a method for computer-implemented monitoring of a goods delivery from a seller to a buyer by using an access-restricted DLT system. The DLT system comprises a first DLT node assigned to the buyer and a second DLT node assigned to the seller. In addition, the DLT system provides at least one smart contract with program instructions for entering and checking delivery orders, order confirmations, and outgoing goods logs in the course of goods deliveries from the seller to the buyer, and for validating the goods delivery. The method comprises, for example, initialising the goods delivery in the DLT system, for example, logging the goods delivery in the DLT system and/or, for example, validating the goods delivery in the DLT system.
Silicone urethane (meth)acrylates can have at least three (meth)acrylate groups and not more urethane groups than (meth)acrylate groups. A method for preparing the silicone urethane (meth)acrylates involves reacting at least one hydroxy functional silicone (meth)acrylate with at least one isocyanate functional urethane (meth)acrylate. Compositions can contain the silicone urethane (meth)acrylates, and are useful for the production of release coatings, protective films, and protective coatings; and for the manufacturing of 3D printed objects by stereolithography.
C08G 18/67 - Unsaturated compounds having active hydrogen
C08G 18/75 - Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic
C09D 11/102 - Printing inks based on artificial resins containing macromolecular compounds obtained by reactions other than those only involving unsaturated carbon-to-carbon bonds
C09D 175/16 - Polyurethanes having carbon-to-carbon unsaturated bonds having terminal carbon-to-carbon unsaturated bonds
22.
SOLID SNEDDS BASED ON A SPECIFIC MIXTURE OF ACRYLIC POLYMERS
A method of preparing a specific solid self-nanoemulsifying drug delivery system involves applying an obtained self-nanoemulsifying drug delivery system on a mixture. The mixture contains (ia) 60 to 90 parts by weight of at least one dimethylaminoethyl methacrylate-butyl methacrylate-methyl methacrylate copolymer; (iia) 10 to 40 parts by weight of at least one methacrylic acid-ethyl acrylate copolymer; and (iiia) optionally, at least one additive; where the sum of (a) and (iia) is 100 parts by weight. The solid self-nanoemulsifying drug delivery system obtained by the method of the present invention is useful as a medicament.
11 (aminocarboxypropyltransferase, EC 2.5.1) are used for the enzymatic catalysis. The invention makes accessible new substrates in the enzymatic production of L-glufosinate and its phosphoesters.
A 11 is used for the enzymatic catalysis. The invention makes accessible new substrates in the enzymatic production of L-glufosinate and its phosphoesters.
The invention relates to a method for the computer-implemented control of a goods delivery from a goods sender to a goods recipient using an access-restricted DLT system (182). The DLT system (182) comprises a first DLT node allocated to the goods recipient and a second DLT node allocated to the goods sender. Furthermore, the DLT system (182) provides at least one smart contract with program instructions for entering and checking delivery orders (190), order confirmations (191) and goods issue logs during goods deliveries from the goods sender to the goods recipient and for validating the goods delivery. The method comprises, for example, initiating the goods delivery in the DLT system (182), for example logging the goods delivery in the DLT system (182) and/or for example validating the goods delivery in the DLT system (182).
H04L 9/32 - Arrangements for secret or secure communications; Network security protocols including means for verifying the identity or authority of a user of the system
G06Q 10/0875 - Itemisation or classification of parts, supplies or services, e.g. bill of materials
Hydroxy-substituted sphingolipids are useful as constituents in cosmetic formulations. A method for preparing the sphingolipids involves reacting a lysosphingolipid with a hydroxycarboxylic acid or an intramolecular cyclic ester of a hydroxycarboxylic acid. The sphingolipids can be used for therapy or prophylaxis of cell damage, including skin cell damage and cell damage induced by UV radiation.
C07C 235/08 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
C07C 235/74 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton
A process for the epoxidation of propene involves reacting propene with hydrogen peroxide, in the presence of a methanol solvent and a shaped titanium zeolite epoxidation catalyst in a fixed bed reactor. The process then involves recovering methanol from the reaction mixture, treatment of the recovered methanol by passing it through a bed of an acidic ion exchange resin, and recycling the treated methanol to the epoxidation reaction; as well as regeneration of the acidic ion exchange resin. Catalyst breakage can be reduced or avoided by washing the regenerated bed of an acidic ion exchange resin with methanol until the methanol exiting the resin bed has an apparent pH higher than 1.8, before methanol treated with the acidic ion exchange resin is recycled to the epoxidation reaction.
C07D 301/12 - Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with hydrogen peroxide or inorganic peroxides or peracids
30.
APPARATUS AND PROCESS FOR PRODUCING NANOCARRIERS AND/OR NANOFORMULATIONS
An apparatus and corresponding process can be used for producing nanocarriers and or nanoformulations and corresponding process products. The apparatus is characterized by a vertical orientation of the feed conduits leading to active element. The feed conduits are nested within one another and are axially movable in terms of their orientation to one another. The process provides for the mixing of at least two liquid phases with different acidities. The volume flow of the first phase is greater than that of the second phase.
The present invention relates to the electrochemical production of hydrogen and lithium hydroxide from Li+-containing water using a LiSICon membrane. The problem addressed by the present invention is that of specifying a process which is operable economically even on an industrial scale. The process shall especially exhibit a high energy efficiency and achieve a long service life of the membrane even when the employed feed contains impurities harmful to LiSICon materials. A particular aspect of the process is that the cell simultaneously separates off the lithium via the membrane and effects electrolysis of water. An essential aspect of the process is that the electrochemical process is performed in a basic environment, more precisely at pH 9 to 13. The pH is adjusted by addition of a basic compound to the feed.
C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
C25B 11/00 - Electrodes; Manufacture thereof not otherwise provided for
C02F 103/16 - Nature of the water, waste water, sewage or sludge to be treated from metallurgical processes, i.e. from the production, refining or treatment of metals, e.g. galvanic wastes
32.
ELECTROCHEMICAL PRODUCTION OF HYDROGEN AND LITHIUM HYDROXIDE UNDER DEFINED FLOW CONDITIONS
The problem addressed by the present invention is that of specifying a process for electrochemical production of LiOH from Li+-containing water using an electrochemical cell having a LiSICon membrane which is operable economically even on an industrial scale. The process shall especially have a high energy efficiency and achieve a long service life of the membrane even when the employed feed contains impurities damaging to LiSICon materials. The problem is solved by adjusting the flow conditions in the anodic compartment of the electrochemical cell such that the anolyte flows along the membrane at a certain minimum flow rate.
C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
The problem addressed by the present invention is that of specifying a process for producing lithium hydroxide which is very energy efficient. The process shall especially operate without consumption of thermal energy. The process shall be able to handle, as raw material, Li-containing waters generated during digestion of spent lithium-ion batteries. The LiOH produced by the process shall have a high purity sufficient for direct manufacture of new LIB. The process shall achieve a high throughput and have small footprint in order that it can be combined with existing processes for workup of used LIB/for production of new LIB to form a closed, continuous production loop. The process according to the invention is an electrolytic membrane process operating with a LiSICon membrane. It is a special aspect of the process that the electrolysis is operated up to the precipitation limit of the lithium hydroxide.
C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
C25B 11/00 - Electrodes; Manufacture thereof not otherwise provided for
C02F 103/16 - Nature of the water, waste water, sewage or sludge to be treated from metallurgical processes, i.e. from the production, refining or treatment of metals, e.g. galvanic wastes
34.
CATALYST FOR EPOXIDATION REACTIONS AND PREPARATION THEREOF
The present invention relates to processes for preparing propylene oxide, comprising reaction of propene with ethylbenzene hydroperoxide in the presence of a catalyst, as well as to catalysts employed in such processes and to methods for their manufacture. The catalysts of the invention are prepared in a process comprising sol-gel-synthesis of catalyst hydrogel-precursor, drying of catalyst hydrogel precursor, calcining of dried catalyst hydrogel-precursor, and optionally hydrophobizing the calcined catalyst hydrogel-precursor. The catalysts of the invention comprise amorphous titanium doped silica comprising pentahedrally coordinated titanium species.
B01J 35/10 - Solids characterised by their surface properties or porosity
C07D 301/19 - Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic hydroperoxides
C07D 303/04 - Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
The invention relates in particular to a process for the preparation of DL/LD-methionine diketopiperazine (I) characterized in that a DD/LL-methionylmethionine-containing aqueous solution or suspension, which has a pH of 3 to 7, measured using a pH electrode at 20° C., is reacted at a temperature of 150 to 220° C., preferably at 170 to 210° C., until an aqueous solution or suspension has formed containing at least a proportion of 30 mol %, preferably 50 mol %, especially 60 mol % of DL/LD-methionine diketopiperazine, based on the total content of DL/LD- and DD/LL-methionine diketopiperazine in the reaction mixture. This process forms part of an overall process for the preparation of DL/LD-methionylmethionine, which is obtained by hydrolysis from the DL/LD-methionine diketopiperazine (I) produced initially.
The invention relates in particular to a process for the preparation of DL/LD-methionine diketopiperazine (I) characterized in that a DD/LL-methionylmethionine-containing aqueous solution or suspension, which has a pH of 3 to 7, measured using a pH electrode at 20° C., is reacted at a temperature of 150 to 220° C., preferably at 170 to 210° C., until an aqueous solution or suspension has formed containing at least a proportion of 30 mol %, preferably 50 mol %, especially 60 mol % of DL/LD-methionine diketopiperazine, based on the total content of DL/LD- and DD/LL-methionine diketopiperazine in the reaction mixture. This process forms part of an overall process for the preparation of DL/LD-methionylmethionine, which is obtained by hydrolysis from the DL/LD-methionine diketopiperazine (I) produced initially.
C07D 241/08 - Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
A polymeric blend contains a polyether block amide and a thermoplastic polymer, where the polyether block amide is based on a subunit 1 and a subunit 2. Subunit 1 is composed of at least one linear aliphatic diamine containing 5 to 15 carbon atoms and at least one linear aliphatic dicarboxylic acid containing 6 to 16 carbon atoms. Subunit 2 is composed of at least one polyether diol containing at least 3 carbon atoms per ether oxygen and primary OH groups at the chain ends. The sum total of the carbon atoms from diamine and dicarboxylic acid is an odd number and is 19 or 21 carbon atoms. The number-average molar mass of the subunit 2 is 200 to 900 g/mol. The thermoplastic polymer is selected from an ethylene/vinylene acetate, a thermoplastic polyester elastomer, a polyolefin elastomer, thermoplastic polyurethane, or any mixture thereof.
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
C08G 69/40 - Polyamides containing oxygen in the form of ether groups
C08J 9/12 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
Present invention relates to an apparatus (0) for producing nanocarriers and/or nanoformulation and a process for producing a nanocarrier and/or a nanoformulation by means of this apparatus (0). According to inventive preparation, a first liquid phase (A) and the second liquid phase (B) are mixed first to give the primary mixture (A+B) by means of a static mixer (4). In a subsequence mixing step primary mixture (A+B) is diluted with a third liquid (C). An important aspect of apparatus (0) is the arrangement of the static mixer (4) inside a linear pipe (7) conducting third liquid phase (C). Thus, the primary mixture (A+B) exiting the mixer (4) is instantaneously diluted with (C) to give secondary mixture (A+B+C). The volume flow of the third mixture (C) is chosen larger than the volume flow of the primary mixture (A+B). By these measures, nanocarriers with improved morphology and homogeneity are produced. Encapsulation efficiency was enhanced as well.
B01F 23/45 - Mixing liquids with liquids; Emulsifying using flow mixing
B01F 25/313 - Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced in the centre of the conduit
B01F 25/4314 - Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor with helical baffles
B01F 25/53 - Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle in which the mixture is discharged from and reintroduced into a receptacle through a recirculation tube, into which an additional component is introduced
B33Y 80/00 - Products made by additive manufacturing
Brushware contains the constituents of monofilaments or bristles, and at least one head, handle, and/or neck. The constituents contain or are made of polymers from the same polymer class selected from among polymers and/or copolymers, and wherein the polymer class is selected from polyamides or polyesters.
A46D 1/00 - Bristles; Selection of materials for bristles
D01F 6/04 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polyolefins
D01F 6/60 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyamides
D01F 6/80 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from copolycondensation products from copolyamides
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS (Germany)
Inventor
Nagarajan, Sanjanaa
Roy, Suki
Böhl, Florian
Whelan, Rose
Huang, Lingzhi
Wong, Kit Yeng
Chan, Sarah
Franke, Daniel
Lyko, Frank
Venkatesh, Geetha
Raddatz, Günter
Tönges, Sina
Pfefferle, Walter
Wessel, Rainer
Abstract
The present invention is related to a DNA methylation-based array comprising at least: a first plurality of distinct locations, each location having at least one probe molecule comprising a nucleic acid sequence complementary to a CpG site from a first plurality of CpG sites of a first animal species; and a second plurality of distinct locations, each location having at least one probe molecule comprising a nucleic acid sequence complementary to a CpG site from a second plurality of CpG sites of a second animal species, wherein the first and second animal species are each independently selected from the group consisting of virus, mammals, birds and aquatic animals, and - the mammal is at least one livestock or animal cell line; - the bird is at least one poultry; and - the aquatic animal is at least one crustacean, cephalopod or fish, and wherein the first plurality of CpG sites comprises at least 1000 CpG sites of the first animal species; and the second plurality of CpG sites comprises at least 1000 CpG sites of the second animal species.
The present invention is related to a method of detecting DNA methylation and/or determining a test methylation profile from genomic material contained in a biological sample obtained from a test animal-derived product, the method comprises the step of: - contacting a genomic material sample from the test animal-derived product with a DNA methylation array specific for species of the test animal, wherein the test animal is a monogastric livestock.
C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
42.
IDENTIFYING BREEDING CONDITIONS OF LIVESTOCK USING EPIGENETICS
The present invention relates to a method of certifying a test animal-derived product sample, the method comprising the steps of: (a) determining a test methylation profile of one or more pre-selected methylation sites within the genomic material obtained from the test animal derived product sample; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile obtained from a control animal of the same biological taxon of the test animal from which the product sample is derived from, where the control animal is bred under a known distinct type of animal husbandry; wherein a significant similarity in the test methylation profile of (a) compared to the reference methylation profile from the control animal, is indicative of the test animal having been bred under the same distinct type of animal husbandry as the control animal and the test animal-derived product is certified so; wherein a difference in the test methylation profile of (a) compared to the reference methylation profile of the control animal, is indicative of the test animal having been bred under another distinct type of animal husbandry as the control animal; and wherein the pre-selected methylation sites are CpG sites selected from genes or regions of genomic DNA from the control and test animal that show the highest degree of methylation variation during the training of the method; and wherein the test methylation profile has significant similarity to the reference methylation profile when the test methylation profile overlaps with the reference methylation profile that is defined by multiple training samples using Principal Component analysis and/ or Multi-Dimensional Scaling; and wherein the methylation profiles are determined using at least one method selected from the group consisting of PCR, methylation- specific PCR, real-time methylation-specific PCR, PCR assay using a methylation DNA- specific binding protein, quantitative PCR, a DNA chip-based assay, pyrosequencing, bisulfate pyrosequencing, Methylated DNA immunoprecipitation-sequencing and combinations thereof; andwherein the test animal is selected from livestock or poultry.
The present invention relates to a composition comprising: - an isolated endophyte, wherein the endophyte is a strain of Rhizobium metallidurans, and - an adjuvant and wherein the Rhizobium metallidurans strain has Accession Number DSM34351.
The present invention relates to a composition comprising: - an isolated endophyte, wherein the endophyte is a strain of Paenibacillus xylanexedens, and - an adjuvant, wherein the strain of Paenibacillus xylanexedens has Accession Number DSM 34353.
The present invention is related to a method of determining suitability of at least one Chinese Hamster Ovary (CHO) test cell line for optimal heterologous protein production, the method comprising: (a) determining a test methylation profile from genomic material obtained from the CHO test cell line; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile, wherein the reference methylation profile comprises the methylation status of more than one CpG site from at least one CHO reference cell line that displays at least one phenotype of interest for optimal heterologous protein production, wherein a significant similarity in the test methylation profile of (a) compared to the reference methylation profile, is indicative of the CHO test cell line being suitable for optimal heterologous protein production and wherein the test methylation profile and reference methylation profile are from CpG sites from the CHO cell genome and are determined using DNA methylation- bead-based array.
C12Q 1/6881 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
The invention relates to a composition for producing polyurethane, preferably PU foam, particularly preferably rigid PU foam, comprising a polyisocyanate component, a polyol component, optionally a blowing agent, at least one solid filler, and optionally at least one catalyst that catalyzes the formation of a urethane or isocyanurate bond, the composition containing at least one surfactant based on a quarternary ammonium compound.
01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
Chemicals used in industry; Lipids for use in industry, in particular sphingolipids for use in industry; Ceramides for use in industry; Chemicals used in industry, namely, chemical ingredients, in particular active chemical ingredients, raw materials (chemical) and chemical agents as well as additives and auxiliary agents for use in the manufacture of non-medicated cosmetics, toiletry preparations and pharmaceuticals
Spherical amorphous, non-porous silicas are useful for oral compositions. A method of making the spherical amorphous, non-porous silicas is also provided.
A process for producing alkoxysiloxanes by thermal reaction of at least one waste silicone with at least one alkali metal alkoxide and at least one alcohol. The process includes a first step of reacting the at least one waste silicone by mixing with at least one alcohol and at least one alkali metal alkoxide with heating, but without removing any potentially occurring water from the reaction mixture, and a second step of neutralizing the reaction mixture resulting from this reaction using at least one Brønsted acid and separating the solid constituents, and subsequently isolating the alkoxysiloxane by thermal separation of volatile compounds.
C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
Processes may produce alkoxysiloxane(s) by reaction of siloxane parent structure(s) with alkali metal alkoxide(s). Such processes may include reacting siloxane parent structure(s) by mixing with alkali metal alkoxide(s) with heating and optionally adding silicon dioxide, but without adding alcohol and without removal of any potentially occurring water from the reaction mixture; and neutralizing the resulting reaction mixture by adding Brønsted acid(s), optionally solvent(s), and preferably separating solid constituents; and subsequently isolating the alkoxysiloxane(s) by thermally separating volatile compounds. The siloxane parent structure(s) may be a hexamethylcyclotrisiloxane (D3), octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), dodecamethylcyclohexasiloxane (D6), mixture of cyclic branched D/T type siloxanes, silicone oils preferably including at least 100 D units, polydimethylsiloxanediol(s), and/or α,ω-divinylsiloxane(s).
The present invention is directed to polyalkyl(meth)acrylate-based polymers comprising defined amounts of long-chain alkyl (meth)acrylates, their preparation, lubricant compositions comprising such polymers and their use to improve the thickening efficiency and low temperature performance of lubricant compositions, especially of engine oil (EO) compositions.
A process for producing one or more alkoxysiloxanes by thermal reaction of at least one siloxane parent structure with at least one alkali metal alkoxide and at least one alcohol, where the process includes mixing, while heating, the at least one siloxane parent structure with the at least includes one alcohol and the at least one alkali metal alkoxide to form a reaction mixture, neutralizing the reaction mixture by addition of at least one Brønsted acid and optionally with addition of at least one solvent, and subsequently isolating the one or more alkoxysiloxanes by thermal separation of volatile compounds. Potentially occurring water is not removed from the reaction mixture and the reaction mixture does not include solvents which form an azeotrope with water and/or further dehydrating agents.
Process for producing one or more alkoxysiloxanes by reaction of at least one siloxane parent structure with at least one alkali metal alkoxide, wherein the process comprises a first step of reacting at least one siloxane parent structure by mixing with at least one alkali metal alkoxide with heating and optionally with addition of silicon dioxide but without addition of alcohol and without removal of any potentially occurring water from the reaction mixture and a second step of neutralizing the reaction mixture resulting from the first step by addition of at least one Bronsted acid, optionally with addition of at least one solvent, and preferably separating solid constituents and subsequently isolating the alkoxysiloxane(s) by thermal separation of volatile compounds, wherein the at least one siloxane parent structure is selected from the group consisting of hexamethylcyclotrisiloxane (D3), octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (Ds), dodecamethylcyclohexasiloxane (Ds), mixtures of cyclic branched siloxanes of the D/T type, silicone oils preferably comprising at least 100 D units, polydimethylsiloxanediols and cvo-divinylsiloxanes.
Process for producing one or more alkoxysiloxanes by thermal reaction of at least one siloxane parent structure with at least one alkali metal alkoxide and at least one alcohol, wherein the process comprises a first step of reacting the at least one siloxane parent structure by mixing with at least one alcohol and at least one alkali metal alkoxide with heating but without removing any potentially occurring water from the reaction mixture, and subsequently a second step of neutralizing the reaction mixture resulting from the first step by addition of at least one Bronsted acid and preferably separating, by filtration, solid constituents, and subsequently isolating the alkoxysiloxane(s) by thermal separation of volatile compounds, wherein the at least one siloxane parent structure is selected from the group consisting of hexamethylcyclotrisiloxane (D3), octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (Ds), dodecamethylcyclohexasiloxane (Ds), mixtures of cyclic branched siloxanes of the D/T type, silicone oils, polydimethylsiloxanediols and cvo-divinylsiloxanes.
Process for producing alkoxysiloxanes by thermal reaction of at least one waste silicone with at least one alkali metal alkoxide and at least one alcohol, wherein the process comprises a first step of reacting the at least one waste silicone by mixing with at least one alcohol and at least one alkali metal alkoxide with heating but without removing any potentially occurring water from the reaction mixture, and a second step of neutralizing the reaction mixture resulting from this reaction using at least one Bronsted acid and separating the solid constituents, and subsequently isolating the alkoxysiloxane by thermal separation of volatile compounds.
A method for the preparation of homo- and copolymers of alkyl (meth)acrylates having a low residual monomer content involves preparing a reaction mixture containing monomers, charging the reaction mixture, heating the reaction mixture, adding an additional monomer after initial monomer conversion, and optional further processing of the reaction mixture. The homo- and copolymers of alkyl (meth)acrylates obtained by this method as useful in lubricant applications.
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
C10M 169/04 - Mixtures of base-materials and additives
Composition for producing polyurethane foam, in particular rigid polyurethane foam, comprising at least an isocyanate component, a polyol component, optionally a catalyst that catalyses the formation of a urethane or isocyanate linkage, blowing agents, wherein the composition comprises polyester-polysiloxane block copolymers.
C08J 9/14 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
59.
COMPOSITIONS COMPRISING A GRAPHENE-BASED MATERIAL AS LUBRICANT ADDITIVES
Nanoparticle compositions contain a graphene-based material. A preparation process involves providing several components and milling a mixture. The nanoparticle compositions can be used as a lubricant additive to improve tribological performance, in particular to improve anti-friction and anti-wear performance on metal parts. A corresponding lubricant composition contains these nanoparticle compositions.
C08F 267/06 - Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated polycarboxylic acids or derivatives thereof as defined in group on to polymers of esters
C08F 279/06 - Vinyl aromatic monomers and methacrylates as the only monomers
C10M 139/04 - Lubricating compositions characterised by the additive being an organic non-macromolecular compound containing atoms of elements not provided for in groups having a silicon-to-carbon bond, e.g. silanes
C10M 143/12 - Lubricating composition characterised by the additive being a macromolecular hydrocarbon or such hydrocarbon modified by oxidation containing conjugated diene
C10M 169/04 - Mixtures of base-materials and additives
60.
SYNTHETIC MIXED CULTURE RESEMBLING A SKIN MICROBIOME
A process for the recovery of a light boiler and a heavy boiler from a vapor stream, where the process includes: A1) introducing a vapor stream containing a light boiler and a heavy boiler into a column at a point at the bottom of the column, A2) withdrawing a vapor stream, enriched in the light boiler, from the top of the column, A3) withdrawing a liquid stream, enriched in the heavy boiler, from the bottom of the column, and splitting the stream into a partial stream and a partial stream, A4) recycling the stream back into the column at a point above the column, wherein the stream is kept essentially adiabatically during the recycling, A5) withdrawing a stream, enriched in a middle boiler, from the middle section of the column and splitting the stream into a partial stream and a partial stream, A6) cooling the partial stream in the heat exchanger to provide the cooled stream and recycling the stream as stream back into the column at an introduction point below the top of the column, and A7) withdrawing the partial stream, enriched in the heavy boiler, and the partial stream, enriched in the middle boiler.
B01D 3/34 - Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping with one or more auxiliary substances
B01D 3/32 - Other features of fractionating columns
Mixture compositions contain A) crosslinked organopolysiloxanes having organopolysiloxane units linked by a building block containing polyether groups, and B) crosslinked organopolysiloxanes having organopolysiloxane units bridged by a bridging siloxane. The mixture compositions are useful, for example, as an emulsifier, for stabilizing formulations, and for dispersion of solid pigments.
A process for purifying ethylene cyanohydrin involves incubating an industrial grade ethylene cyanohydrin product with at least one titanium(IV)alkoxide. Ethylene cyanohydrin products with purities of >99% contain less than 0.05% of ethylene glycol (EG), and/or contain a water content of less than 1000 ppm.
C07C 253/16 - Preparation of carboxylic acid nitriles by reaction of cyanides with lactones or compounds containing hydroxy groups or etherified or esterified hydroxy groups
C07C 255/12 - Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
66.
Process for separation of methanol and methyl (meth)acrylate
A method for preparing flexible slabstock polyurethane foam comprising contacting at least one polyisocyanate with at least one polyol in the presence of at least one polyurethane additive selected from the group consisting of a blowing agent, a cell stabilizer, and a crosslinker, and a catalyst composition comprising at least one compound represented by formula (I): (I), wherein R1, R2, R3, R4, and R513266 alkenyl linear or branched.
C07C 213/02 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
C07C 213/08 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
68.
ADHESION OF BLOWING AGENT-CONTAINING PARTICLES BASED ON POLYIMIDES OR POLYACRYLATES
A process for the production of functionalized particle foam mouldings based on a thermoplastic base material with a glass transition temperature of at least 100° C. involves functionalization of base particles.
C08J 9/14 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
69.
MATRIX RESIN FOR PRODUCTION OF FIBRE COMPOSITE MATERIALS
A composition contains at least one aldehyde (A), at least one phenolic compound (B), and at least one amine (C) bearing at least two amino groups selected from primary and secondary amino groups. At least one of these compounds bears at least one (meth)acrylate group. A fibre-reinforced composition contains the composition. The compositions can be cured in a process, and fibre composite materials/thermosets are obtainable by the process.
C08G 14/06 - Condensation polymers of aldehydes or ketones with two or more other monomers covered by at least two of the groups of aldehydes with phenols and monomers containing hydrogen attached to nitrogen
C08J 3/24 - Crosslinking, e.g. vulcanising, of macromolecules
C08J 3/28 - Treatment by wave energy or particle radiation
70.
ENZYME BASED PRODUCTION OF SPECIALIZED PRO-RESOLVING MEDIATORS (SPMS) VIA DOCOSAHEXAENOIC ACID (DHA) AND EICOSAPENTAENOIC ACID (EPA)
The present invention refers to a method for producing hydroxylated fatty acids by oxidizing at least one unsaturated fatty acid by at least one lipoxygenase and thereafter reducing the obtained compound by at least one peroxidase and/or heating. Furthermore, the present invention refers to the compound obtained by said method.
09 - Scientific and electric apparatus and instruments
41 - Education, entertainment, sporting and cultural services
Goods & Services
Apparatus for recording, transmission or reproduction of
sound or images; data processing equipment; computers. Education; entertainment; sporting and cultural activities;
entertainment provided via the internet.
72.
PROCESS FOR ACID HYDROLYSIS OF PURE POLYLAUROLACTAM
An improved process can be used for the acid hydrolysis of polylaurolactam with sulfuric acid. An especially suitable starting material is polylaurolactam which is intended for recycling and which is characterized by a low laurolactam content.
C07C 227/20 - Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters by hydrolysis of N-acylated amino acids or derivatives thereof, e.g. hydrolysis of carbamates
73.
A FABRIC SOFTENER ACTIVE COMPOSITION FOR PREPARING A TRANSPARENT FABRIC SOFTENER COMPOSITION
A fabric softener active composition, comprising, based on the total weight of the fabric softener active composition: A) 20 to 80 wt. -%of at least one solubilizer, which is selected from the group consisting of mono long-chain-alkyl amido quaternary ammonium salts, alkoxylated mono long-chain-alkyl quaternary ammonium salts, and alkoxylated mono long-chain-alkyl amido quaternary ammonium salts, and B) 10 to 50 wt. -%of at least one softening ingredient, which is selected from the group consisting of di-long-chain-alkyl quaternary ammonium salts, di-long-chain-alkyl ester quaternary ammonium salts, di-long-chain-alkyl imidazoline quaternary ammonium salts, di-long-chain-alkyl amido quaternary ammonium salts, ethoxylated di-long-chain-alkyl ester quaternary ammonium salts, ethoxylated tri-long-chain-alkyl ester quaternary ammonium salts and ethoxylated di-long-chain-alkyl amido quaternary ammonium salts. A transparent fabric softener composition and a fabric softener product are also provided.
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS (Germany)
Inventor
Nagarajan, Sanjanaa
Roy, Suki
Whelan, Rose
Böhl, Florian
Lyko, Frank
Tönges, Sina
Abstract
The present invention relates to a method of certifying a test animal-derived product sample, the method comprising the steps of: (a) determining a test methylation profile of one or more pre-selected methylation sites within the genomic material obtained from the test animal derived product sample; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile obtained from a control animal of the same biological taxon of the test animal from which the product sample is derived from, where the control animal is not slaughtered by a single cut across the throat severing both carotid arteries, both jugular veins, both vagus nerves, trachea and/or esophagus and/or the control animal is not bled to death wherein a difference in the test methylation profile of (a) compared to the reference methylation profile from the control animal, is indicative of the test animal having been slaughtered by a single cut across the throat severing both carotid arteries, both jugular veins, both vagus nerves, trachea and/or oesophagus and/or of the test animal having been bled to death and the test animal-derived product is certified so, and wherein the pre-selected methylation sites are CpG sites selected from genes or regions of genomic DNA from the control and test animal that shows the highest degree of methylation variation during the training of the method.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
75.
A FABRIC SOFTENER ACTIVE COMPOSITION FOR PREPARING A TRANSPARENT FABRIC SOFTENER COMPOSITION
A fabric softener active composition, comprising, based on the total weight of the fabric softener active composition: A) 20 to 80wt. %of at least one solubilizer, which is selected from the group consisting of mono long-chain-alkyl quaternary ammonium salts, mono long-chain-alkyl amido quaternary ammonium salts, alkoxylated mono long-chain-alkyl quaternary ammonium salts, and alkoxylated mono long-chain-alkyl amido quaternary ammonium salts, and B) 10 to 50wt. %of at least one softening ingredient, which is selected from the group consisting of di-long-chain-alkyl quaternary ammonium salts, di-long-chain-alkyl ester quaternary ammonium salts, di-long-chain-alkyl imidazoline quaternary ammonium salts, di-long-chain-alkyl amido quaternary ammonium salts, ethoxylated di-long-chain-alkyl ester quaternary ammonium salts, ethoxylated tri-long-chain-alkyl ester quaternary ammonium salts and ethoxylated di-long-chain-alkyl amido quaternary ammonium salts. A transparent fabric softener composition and a fabric softener product are also provided.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Downloadable and recorded content; Databases; Media content; Software; Application software; Data and file management and database software; Computer software, computer programs, Especially Calculation programs for animal nutrition, and being databases for analysing amino acids in foodstuffs for animals relating to animal nutrition and aquaculture; Office and business applications; Artificial intelligence software and Machine learning software, Especially Artificial intelligence software for analysis; Software for monitoring, analysing, controlling and running physical world operations; Computer programs [downloadable software], in relation to the following fields: Remote security; Virtual and augmented reality software; Web application and server software; Content management software; System and system support software, and firmware; Information technology and audio-visual, multimedia and photographic devices; Magnets, magnetizers and demagnetizers; Scientific and laboratory devices for treatment using electricity; Apparatus, instruments and cables for electricity; Optical devices, enhancers and correctors; Safety, security, protection and signalling devices; Diving equipment; Navigation, guidance, tracking, targeting and map making devices; Measuring, detecting, monitoring and controlling devices; Testing and quality control devices; Measuring devices; Time measuring instruments (not including clocks and watches); Weight measuring instruments; Controllers and regulators; Sensors, detectors and monitoring instruments, Apparatus for scientific research and laboratories, Teaching apparatus and simulators; Physical analysing apparatus [other than for medical use]; Photoelectronic spectroscopy analysers; Apparatus for analysing foodstuffs for animals; Laboratory apparatus and instruments; Devices for analyzing genome information; Devices for analyzing protein sequence used as laboratory apparatus; Laboratory devices for detecting genetic sequences. Science and technology services; Industrial analysis and research services; Development and research, in the following fields: Diagnostic preparations; Agricultural research; Biotechnological research relating to agriculture; Professional consulting services and advice about agricultural chemistry; Scientific consultancy relating to the production of foodstuffs for animals, Relating to the following sectors: Use of foodstuff components; Technical consultancy, Relating to the following sectors: feed industry; Scientific information relating to the use of chemicals in agriculture; Medical and pharmacological research services; Surveying and exploration services; Natural science services; Earth science services; Scientific and technical consultancy in the agriculture sector in relation to the use of animal feed components; Chemistry services; Engineering services; Bacteriological or chemical laboratory services; Physics [research]; IT services, namely development, programming and implementation of software, development of computer hardware, hosting, software as a service (SaaS) and rental of software, rental of computer hardware and installations, IT consultancy and information, IT security, protection and repair, data duplication and conversion, data coding; Testing, authentication and quality control; Design services. Medical services; Animal healthcare services; Animal healthcare services; Animal grooming services; Human healthcare services; Agriculture, aquaculture, horticulture and forestry services; Aquacultural services.
77.
METHOD FOR PREPARING 3-HYDROXY-3-METHYLBUTYRIC ACID (HMB) OR SALTS THEREOF
A method for preparing 3-hydroxy-3-methylbutyric acid (HMB) or salts thereof from tertbutanol and carbon monoxide, may include reacting tert-butanol in an aqueous mixture with carbon monoxide under electrolytic conditions. The electrolytic conditions may include applying an electric potential to the aqueous reaction mixture in a range of from 1.5 and 25 V and/or operating electrodes at a current density in a range of from 1 to 10.000 A/m2. The electric potential may be applied to the aqueous mixture using a diamond anode and/or a steel cathode. The reaction may be conducted in the presence of at least one conducting electrolyte.
The invention relates to a process for producing zirconium phosphate by means of flame spray pyrolysis, zirconium phosphate obtainable by this process and the use thereof in batteries especially to encapsulate lithium mixed oxide particles.
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS (Germany)
Inventor
Lingenberg, Annika
Tönges, Sina
Lyko, Frank
Whelan, Rose
Böhl, Florian
Roy, Suki
Nagarajan, Sanjanaa
Giatsis, Christos
Pelzer, Stefan
Abstract
The present invention is related to a method of determining if a test animal and/or a test animal from which a product is derived has been treated and/or is currently undergoing treatment with at least one antibiotic and/or veterinary chemical, the method comprising: (a) determining a test methylation profile from the genomic material contained in a biological sample obtained from the test animal and/or the animal-derived product; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile obtained from a control animal of the same biological taxon of the test animal, where the control animal was not treated and/or is not currently undergoing treatment with at least one antibiotic and/or veterinary chemical, wherein a difference in the test methylation profile of (a) compared to the reference methylation profile from the control animal, is indicative of the test animal having been treated and/or is currently undergoing treatment with at least one antibiotic and/or veterinary chemical; and wherein the test animal is an aquatic animal; and the veterinary chemical is an anti-parasitic, an anti- viral, a feed additive, a water additive, a disinfectant, glutaraldehyde, and/ or formalin used in aquaculture.
C12Q 1/6809 - Methods for determination or identification of nucleic acids involving differential detection
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
09 - Scientific and electric apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Downloadable and recorded content; Databases; Media content; Software; Application software; Data and file management and database software; Computer software, computer programs, Especially Calculation programs for animal nutrition, and being databases for analysing amino acids in foodstuffs for animals relating to animal nutrition and aquaculture; Office and business applications; Artificial intelligence software and Machine learning software, Especially Artificial intelligence software for analysis; Software for monitoring, analysing, controlling and running physical world operations; Computer programs [downloadable software], in relation to the following fields: Remote security; Virtual and augmented reality software; Web application and server software; Content management software; System and system support software, and firmware; Information technology and audio-visual, multimedia and photographic devices; Magnets, magnetizers and demagnetizers; Scientific and laboratory devices for treatment using electricity; Apparatus, instruments and cables for electricity; Optical devices, enhancers and correctors; Safety, security, protection and signalling devices; Diving equipment; Navigation, guidance, tracking, targeting and map making devices; Measuring, detecting, monitoring and controlling devices; Testing and quality control devices; Measuring devices; Time measuring instruments (not including clocks and watches); Weight measuring instruments; Controllers and regulators; Sensors, detectors and monitoring instruments, Apparatus for scientific research and laboratories, Teaching apparatus and simulators; Physical analysing apparatus [other than for medical use]; Photoelectronic spectroscopy analysers; Apparatus for analysing foodstuffs for animals; Laboratory apparatus and instruments; Devices for analyzing genome information; Devices for analyzing protein sequence used as laboratory apparatus; Laboratory devices for detecting genetic sequences. Publishing, reporting, and writing of texts; Education, entertainment and sport services; Providing of instruction and further training for specialists in the field of animal nutrition; Arranging and conducting of conferences, congresses and symposiums; Organisation of exhibitions for cultural and/or educational purposes; Publication of books, newspapers and periodicals; Arranging and conducting of seminars and workshops, in particular for specialists in the field of animal nutrition; Translation and interpretation. Science and technology services; Industrial analysis and research services; Development and research, in the following fields: Diagnostic preparations; Agricultural research; Biotechnological research relating to agriculture; Professional consulting services and advice about agricultural chemistry; Scientific consultancy relating to the production of foodstuffs for animals, Relating to the following sectors: Use of foodstuff components; Technical consultancy, Relating to the following sectors: feed industry; Scientific information relating to the use of chemicals in agriculture; Medical and pharmacological research services; Surveying and exploration services; Natural science services; Earth science services; Scientific and technical consultancy in the agriculture sector in relation to the use of animal feed components; Chemistry services; Engineering services; Bacteriological or chemical laboratory services; Physics [research]; IT services, namely development, programming and implementation of software, development of computer hardware, hosting, software as a service (SaaS) and rental of software, rental of computer hardware and installations, IT consultancy and information, IT security, protection and repair, data duplication and conversion, data coding; Testing, authentication and quality control; Design services. Medical services; Animal healthcare services; Animal healthcare services; Animal grooming services; Human healthcare services; Agriculture, aquaculture, horticulture and forestry services; Aquacultural services.
01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
Chemicals used in industry; lipids for use in industry, in
particular sphingolipids for use in industry; chemicals used
in industry, namely solutions or mixtures containing lipids
and vegetable oils as an essential ingredient or consisting
predominantly of lipids and vegetable oils, as additive (s)
for use in the cosmetic industry and pharmaceutical
industry; ceramides for use in industry; chemicals used in
industry, namely solutions or mixtures containing ceramides
and vegetable oils as an essential ingredient or consisting
predominantly of ceramides and vegetable oils, as additive
(s) for use in the cosmetic industry and pharmaceutical
industry; chemicals used in industry, namely chemical
ingredients, in particular active chemical ingredients, raw
materials (chemical) and chemical agents as well as
additives and auxiliary agents for use in the manufacture of
cosmetics, toiletry preparations and pharmaceuticals.
A method for preparing guanidino acetic acid involves reacting cyanamide and glycine in an aqueous reaction mixture in the presence of a base. The ammonia content in the reaction mixture is controlled to be below 20 g/L, and the dicyandiatrade content in the reaction mixture is kept below 5 wt.-%.
C07C 277/02 - Preparation of guanidine or its derivatives, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups of guanidine from cyanamide, calcium cyanamide or dicyandiamides
83.
DETECTING ANTIBIOTIC AND/OR CHEMICAL USE IN ANIMALS USING EPIGENETIC MEANS
The present invention is related to a method of determining if a test animal and/or a test animal from which a product is derived has been treated and/or is currently undergoing treatment with at least one antibiotic and/or veterinary chemical, the method comprising: (a) determining a test methylation profile from the genomic material contained in a biological sample obtained from the test animal and/or the animal-derived product; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile obtained from a control animal of the same biological taxon of the test animal, where the control animal was not treated and/or is not currently undergoing treatment with at least one antibiotic and/or veterinary chemical, wherein a difference in the test methylation profile of (a) compared to the reference methylation profile from the control animal, is indicative of the test animal having been treated and/or is currently undergoing treatment with at least one antibiotic and/or veterinary chemical; and wherein the test animal is a terrestrial animal and wherein the veterinary chemical is an anti-parasitic, an anti-viral, a feed additive, a water additive, a disinfectant, glutaraldehyde, and/ or formalin.
C12Q 1/6809 - Methods for determination or identification of nucleic acids involving differential detection
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
09 - Scientific and electric apparatus and instruments
35 - Advertising and business services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Optical devices, enhancers and correctors; Safety, security, protection and signalling devices; Diving equipment; Navigation, guidance, tracking, targeting and map making devices; Measuring, detecting, monitoring and controlling devices; Scientific research and laboratory apparatus, educational apparatus and simulators; Scientific and laboratory devices for treatment using electricity; Apparatus, instruments and cables for electricity; Information technology and audio-visual, multimedia and photographic devices; Downloadable and recorded content; Magnets, magnetizers and demagnetizers. Advertising, marketing and promotional services; Business assistance, management and administrative services. Publishing, reporting, and writing of texts; Education, entertainment and sport services; Providing of instruction and further training for specialists in the field of animal nutrition; Arranging and conducting of conferences, congresses and symposiums; Organisation of exhibitions for cultural and/or educational purposes; Publication of books, newspapers and periodicals; Arranging and conducting of seminars and workshops, in particular for specialists in the field of animal nutrition; Translation and interpretation. Science and technology services; Industrial analysis and research services; Development and research, in the following fields: Diagnostic preparations; Agricultural research; Biotechnological research relating to agriculture; Professional consulting services and advice about agricultural chemistry; Scientific information relating to the use of chemicals in agriculture; Medical and pharmacological research services; Surveying and exploration services; Natural science services; Earth science services; Scientific and technical consultancy in the agriculture sector in relation to the use of animal feed components; Chemistry services; Engineering services; Bacteriological or chemical laboratory services; Physics [research]; IT services, namely development, programming and implementation of software, development of computer hardware, hosting, software as a service (SaaS) and rental of software, rental of computer hardware and installations, IT consultancy and information, IT security, protection and repair, data duplication and conversion, data coding; Testing, authentication and quality control; Design services. Medical services; Animal healthcare services; Animal healthcare services; Animal grooming services; Human healthcare services; Agriculture, aquaculture, horticulture and forestry services; Aquacultural services.
85.
RHAMNOLIPID-PRODUCING CELL HAVING REDUCED GLUCOSE DEHYDROGENASE ACTIVITY
Cells which make rhamnolipids and are genetically modified such that they have a decreased activity, compared to the wild type thereof, are provided. A glucose dehydrogenase and a method for producing rhamnolipids using the cells according to the invention are also provided.
C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
C12N 15/78 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
C12P 19/44 - Preparation of O-glycosides, e.g. glucosides
C12N 15/52 - Genes encoding for enzymes or proenzymes
86.
SILICONE URETHANE (METH)ACRYLATES AND THEIR USE IN COATING COMPOSITIONS
The invention relates to compositions comprising silicone urethane (meth)acrylates having at least three (meth)acrylate groups and not more urethane groups than (meth)acrylate groups, methods for preparing said compositions, as well as release coatings, protective films, and protective coatings obtainable by curing said compositions.
C08G 18/75 - Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic
C08L 75/16 - Polyurethanes having carbon-to-carbon unsaturated bonds having terminal carbon-to-carbon unsaturated bonds
C09D 175/16 - Polyurethanes having carbon-to-carbon unsaturated bonds having terminal carbon-to-carbon unsaturated bonds
C08F 283/12 - Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass on to polysiloxanes
C09D 4/00 - Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond
87.
COMPOSITIONS COMPRISING SELF TANNING AGENTS AND CERTAIN SPHINGOLIPIDS AND/OR CERTAIN SPHINGOID BASES
C07C 233/18 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
The invention provides a method for classifying the gut inflammation status of an avian subject or of a group of avian subjects to be tested, the method comprising the comparison of the average methylation levels within a panel of pre-selected LMRs in the genomic DNA isolated from gut sample material deriving from the individual avian subject or of the group of avian subjects to be tested with the average methylation levels of the same panel of LMRs in the genomic DNA pertaining to one or more reference samples having a negative gut inflammation status.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
G16B 40/00 - ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
89.
COMPOSITION COMPRISING BIOSURFACTANT AND PERSICOMYCIN
The present invention relates to a computer-implemented method for verifying the authenticity of a product, a product comprising an identification substance for verifying the authenticity of the product, the use of an identification substance according to the present invention or of a product according to the present invention for verifying the authenticity of a product by means of EPR spectrometry, and a system for verifying the authenticity of a product, wherein the system comprises i) a processing unit adapted for carrying out the method according to the present invention, and ii) comprises or has access to a database with a library of EPR spectra of one, more, or a multitude of identification substances.
G01N 24/10 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using electron paramagnetic resonance
G01R 33/60 - Arrangements or instruments for measuring magnetic variables involving magnetic resonance using electron paramagnetic resonance
C08F 126/06 - Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
C08F 226/06 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
Recombinant bacterial collagen-like protein with an amino acid sequence that is at least ≥ 60% identical to the amino acid sequence of SEQ ID NO:1 characterized in that the amino acid sequence comprises a deletion of at least 38 amino acids at the N-terminus of the amino acid sequence of SEQ ID NO:1 and that the recombinant collagen-like protein is functionalized with ethylenic unsaturated groups.
C07K 14/34 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
Compositions containing at least one ceramide, at least one polyglycerol carboxylic acid ester, and cholesterol in specific ratios by weight are provided.
Polyalkyl (meth)acrylates are useful in compressor oils. A method of increasing the energy efficiency of a compressor involves operating the compressor with a compressor oil containing a polyalkyl (meth)acrylate-based viscosity index improver.
C10M 171/00 - Lubricating compositions characterised by purely physical criteria, e.g. containing as base-material, thickener or additive, ingredients which are characterised exclusively by their numerically specified physical properties, i.e. containing ingredien
94.
USE OF SURFACTANT FORMULATIONS COMPRISING LONG-CHAIN ALCOHOLS IN AQUEOUS POLYURETHANE DISPERSIONS
The use of surfactant formulations comprising long-chain alcohols as additives in aqueous polymer dispersions for production of porous polymer coatings, preferably for production of porous polyurethane coatings, is described.
A composition for use as a multifunctional wax dispersant can treat subterranean formations for the recovery of oil and gas from oil and gas wells. A process can be used for the preparation thereof. A method for treating a crude oil with a wax dispersant composition according to the present invention reduces interfacial tension between the crude oil and the treatment fluids in the recovery of oil and gas from crude oil and gas wells.
C09K 8/584 - Compositions for enhanced recovery methods for obtaining hydrocarbons, i.e. for improving the mobility of the oil, e.g. displacing fluids characterised by the use of specific surfactants
The present invention relates to a method of extracting carbon dioxide (CO2) gas from an aqueous solution comprising dissolved CO2, the method comprising:
(a) contacting the aqueous solution with dissolved CO2 with an organic phase;
(b) heating the aqueous solution and the organic phase to a temperature of at least 50° C., whereby the CO2 migrates from the aqueous solution to the organic phase; and
(c) separating the CO2 from the organic phase,
wherein the aqueous solution comprises at least 50% water by weight at a temperature of 10° C. to and a base; the organic phase has a higher CO2 solubility relative to water solubility; and the aqueous solution and the organic phase are in direct contact with each other and are maintained as two separate phases.
B01D 53/14 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
1,2-propanediol is prepared by a method involving reacting propene with hydrogen peroxide at 50 to 110° C. in the presence of a catalyst mixture, containing a phase transfer catalyst and a polytungstophosphate, in a liquid reaction mixture containing an aqueous phase with a maximum apparent pH of 6 and an organic phase. The method then involves separating the reaction mixture into an aqueous phase containing 1,2-propanediol and an organic phase; recycling at least part of the separated organic phase to the reaction; and recovering 1,2 propanediol from the aqueous phase. The method further involves reacting a tungstate with hydrogen peroxide and phosphoric acid at 5 to 40° C., in the presence of the phase transfer catalyst, in a liquid mixture containing an aqueous and an organic phase, followed by passing at least a part of the resulting organic phase containing the polytungstophosphate and phase transfer catalyst to the initial reaction.
C07C 29/48 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by oxidation reactions with formation of hydroxy groups
C07C 29/80 - Separation; Purification; Stabilisation; Use of additives by physical treatment by distillation
98.
PROCESS FOR OBTAINING MIXTURES CONTAINING METHIONINE AND POTASSIUM HYDROGENCARBONATE
22 (carbonating) at a temperature of 15-60°C to precipitate a mixture containing methionine and potassium hydrogencarbonate as precipitate which contains on average not more than 6.5% by weight of met-met and separating said precipitate from the mother liquor.
C07C 319/20 - Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
C07C 323/58 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
C07K 5/062 - Dipeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
99.
PRESSURE ENHANCED (TRANS)ESTERIFICATION OF (METH)ACRYLATE COMPOUNDS
The present invention discloses a method for pressure enhanced (trans)esterification of (meth)acrylic esters. The method can prepare an alkyl (meth)acrylate product by a (trans)esterification reaction of a reaction mixture. The reaction mixture comprises a (meth)acrylate starting material and a first alcohol which are converted by the (trans)esterification reaction in the presence of a catalyst into the alkyl (meth )acry late product and a side product. The (trans)esterification reaction is carried out in a reactor system. The reactor system comprises a reboiler, a reaction chamber comprising the reaction mixture, a column with a column head, a vapor transfer line, a condenser, a reflux tank, a reflux line, a distillate take off line, and a receiver vessel. Over a predominant amount of time during the (trans)esterification reaction at least a portion of the side product is continuously removed by distillate take off. The given pressure is continuously adjusted to maintain a range of the reaction temperature. The side product is removed in form of a mixture of the side product and the (meth )acry late starting material, and at least a portion of the converted (meth)acrylate starting material is compensated by adding a further amount of the (meth)acrylate starting material to the reaction mixture, preferably via a feed line to the reaction chamber or to the column. The (trans)esterification reaction is started at a pressure above 1.0 bar and the reaction process ends at a pressure of below 1.0 bar.
22), lithium hydroxide (LiOH), sodium methanolate (NaOMe), lithium methanolate (LiOMe), lithium fert-butoxide (LiOt-Bu), lithium /so-propoxide (LiOIPr), preferably wherein the strong basic catalyst comprises one or more compounds selected from the group consisting of lithium methanolate (LiOMe), and most preferably wherein the strong basic catalyst comprises or is lithium methanolate (LiOMe), wherein over a predominant amount of time during the (trans)esterification reaction at least a portion of the side product is continuously removed by distillate take off, and wherein over a predominant amount of time during the (trans)esterification reaction the given pressure is repeatedly adjusted in order to maintain a range of the reaction temperature, wherein the repeated adjustment of the given pressure is performed in pressure stages, preferably wherein the difference between two pressure stages is less than 500 mbar, and wherein the given pressure is repeatedly adjusted in a way to maintain the reaction temperature in the range of from 70°C to not more than 130°C.
