Abstract

The present disclosure provides a porous elastomer, methods of preparing the porous elastomer, and methods of using the porous elastomers. The porous elastomers described herewith may be hydrophilic and hydrophobic porous elastomers derived from a TPPE precursor composite.

IPC Classes  ?

• C09D 153/00 - Coating compositions based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
• B01D 71/80 - Block polymers
• H01M 50/40 - Separators; Membranes; Diaphragms; Spacing elements inside cells
• H01M 50/403 - Manufacturing processes of separators, membranes or diaphragms

Abstract

In accordance with the purposes of the disclosed materials and methods, as embodied and broadly described herein, the disclosed subject matter, in one aspect, relates to a thermoformed polymeric valved conduits for heart valve and methods of using and making thereof. The thermoformed polymeric valved conduits is formed via a thermoforming process that conforms the conduit to a mold; the process forms a conduit that is flexible, resizablke, and/or deformable after being formed.

IPC Classes  ?

• A61F 2/24 - Heart valves
• A61F 2/06 - Blood vessels
• A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
• A61F 2/958 - Inflatable balloons for placing stents or stent-grafts
• B29C 51/26 - Component parts, details or accessories; Auxiliary operations

Abstract

aaaa-disubstitution in PHAs enhances the thermal stability so substantially that the PHAs become melt-processable. Synergistically, this structural modification also endows the PHAs with the mechanical toughness, intrinsic crystallinity, and closed-loop chemical recyclability.

IPC Classes  ?

• C08G 63/08 - Lactones or lactides
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C08G 63/02 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds
• C08G 63/06 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxy carboxylic acids
• C08G 63/668 - Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
• C08G 69/14 - Lactams

Abstract

in situin situ generated dynamic thermosets exhibit intrinsic reprocessability as well as enhanced tensile strength and creep resistance, relative to virgin plastics. This approach avoids the need for de/reconstruction and thus provides the maximum recovery of the endowed energy and materials value of the individual plastics.

IPC Classes  ?

• C07D 403/02 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings
• C07D 403/10 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
• C08K 5/3442 - Heterocyclic compounds having nitrogen in the ring having two nitrogen atoms in the ring
• C07D 229/02 - Heterocyclic compounds containing rings of less than five members having two nitrogen atoms as the only ring hetero atoms containing three-membered rings

Abstract

The present disclosure provides thermoplastic elastomer (TPE) composites, TPE hydrogel composites, TPE gel polymer electrolyte (GPE) composites, methods of preparing the TPE composites, methods of preparing the TPE hydrogel composites, methods of preparing the TPE GPE composites. The thermoplastic elastomer (TPE) composite comprises a first styrenic thermoplastic elastomer and a second styrenic thermoplastic elastomer, wherein the first and second styrenic thermoplastic elastomers each independently comprise at least one non-hydrogenated or hydrogenated styrene block.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes
• H01M 10/0564 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes the electrolyte being constituted of organic materials only

Abstract

Aspects of the present disclosure include a jet impingement cooling system configured to cool high heat flux devices via a cooling fluid. The jet impingement cooling system may include a heatsink and a first supply surface. The heatsink is coupled to the high heat flux device or capable of being coupled to the high heat flux device. The heatsink includes a first impingement surface having exit orifices and impingement regions. The exit orifices are spaced-apart from each other and defined in the first impingement surface. The impingement regions are located between adjacent exit orifices. The first supply surface is spaced-apart from the first impingement surface and includes injection ports spaced-apart from each other and defined in the supply surface. The injection ports are oriented such that impingement jets therefrom are directed to impinge against the impingement regions.

IPC Classes  ?

• H01L 23/473 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing liquids
• F28F 3/12 - Elements constructed in the shape of a hollow panel, e.g. with channels
• H01L 23/367 - Cooling facilitated by shape of device
• H01L 23/467 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing gases, e.g. air
• F28D 15/02 - Heat-exchange apparatus with the intermediate heat-transfer medium in closed tubes passing into or through the conduit walls in which the medium condenses and evaporates, e.g. heat-pipes
• F28F 13/06 - Arrangements for modifying heat transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media
• F28F 27/02 - Control arrangements or safety devices specially adapted for heat-exchange or heat-transfer apparatus for controlling the distribution of heat-exchange media between different channels
• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating

Abstract

The disclosure relates to 2'‐deoxy‐2'‐fluoroarabinonucleic acid (FANA) antisense oligonucleotides that can be utilized to control weeds, invasive plants, or other undesired plants.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• A01H 3/04 - Processes for modifying phenotypes by treatment with chemicals
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A01N 61/00 - Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
• A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermen
• C12N 15/09 - Recombinant DNA-technology

Abstract

A tuber seed cutter sterilization device is disclosed. The tuber seed cutter is configured to receive a flammable gas and sterilize a tuber seed cutter having a rotational blade and a tuber conveyer, the rotational blade is configured to rotate about a longitudinal axis of a rotational shaft. The tuber seed cutter includes a fluid channel configured to receive the flammable gas at an inlet port and direct the flammable gas to a pair of outlet ports, each outlet port of the pair of outlet ports positioned at opposite axial sides of the rotational blade. The flammable gas is configured to be ignited into a flame at each outlet port of the pair of outlet ports and each flame of the pair of outlet ports is configured to heat opposite outer surfaces of the rotational blade.

IPC Classes  ?

• A01C 1/00 - Apparatus, or methods of use thereof, for testing or treating seed, roots, or the like, prior to sowing or planting
• A01C 1/08 - Immunising seed
• A23L 19/10 - Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
• A23L 19/12 - Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops of potatoes
• A23L 3/00 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
• A61L 2/04 - Heat

Abstract

An upflow leach bed reactor configured to contain a substrate is provided. The reactor includes a container comprising a floor and a sidewall and configured to contain the substrate. The reactor further includes a fluid injection system including a plurality of fluid inlet ports arranged in an array across the floor. The fluid inlet ports can be moved between a first position below the substrate and a second position at least partially within the substrate. The reactor can also include a vertical drain extending from the top to the floor, between the substrate and the sidewall, and configured to permit downward liquid flow and inhibit upward liquid flow therethrough. The reactor can further include an inflatable bladder positioned adjacent the top of the container and configured to press downward against a top surface of the substrate.

IPC Classes  ?

• C02F 3/28 - Anaerobic digestion processes
• C02F 11/04 - Anaerobic treatment; Production of methane by such processes
• C02F 3/30 - Aerobic and anaerobic processes

Abstract

The present disclosure relates to a plant or plant part comprising increased expression of a polynucleotide encoding a CYP72A219 polypeptide that confers to the plant or plant part tolerance to HPPD inhibitor herbicides, such as tembotrione or mesotrione. The disclosure further provides kits for identifying herbicide resistant plants and methods for determining whether a plant is herbicide resistant.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C07K 14/415 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

The present disclosure provides recombinant polynucleotide comprising a heterologous regulatory element operably linked to a first nucleic acid sequence encoding a cyanobacterial bicarbonate transporter protein. The disclosure also provides expression vectors comprising the recombinant polynucleotides as well as eukaryotic algae and methods of utilizing the eukaryotic algae for improved carbon removal and biomass production.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C07K 14/195 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria

Abstract

The disclosure relates to compositions and methods for reducing free asparagine concentration in the grain of wheat plants. The compositions comprise wheat plants, plant parts, plant cells, and seeds comprising a loss-of-function mutation in at least one endogenous ASPARAGINE SYNTHETASE 2 (ASN2) gene. The grain of wheat plants has reduced acrylamide-forming potential. Low acrylamide products produced from the grain are also provided.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• A01H 6/46 - Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
• C12N 9/22 - Ribonucleases
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

A power plant system is disclosed. The power plant system includes a combustor, a turbine configured to generate electricity, a carbon capture system configured to remove at least a portion of carbon-based gasses from the flue gas downstream from the combustor, and a thermal storage system including a hot storage unit configured to store heat generated at least by resistively-heated gas at a hot temperature, the hot temperature greater than ambient temperature. The power plant is configured to operate in at least a first mode for storing thermal energy in the thermal storage system and a second mode for releasing the stored thermal energy from the thermal storage system and during the second mode, heat stored in the hot storage unit is transferred to the carbon capture system.

IPC Classes  ?

• F01K 3/12 - Plants characterised by the use of steam or heat accumulators, or intermediate steam heaters, therein having two or more accumulators
• F01K 17/02 - Use of steam or condensate extracted or exhausted from steam engine plant for heating purposes, e.g. industrial, domestic
• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F02C 6/04 - Gas-turbine plants providing heated or pressurised working fluid for other apparatus, e.g. without mechanical power output
• F02C 6/14 - Gas-turbine plants having means for storing energy, e.g. for meeting peak loads
• F02C 6/18 - Plural gas-turbine plants; Combinations of gas-turbine plants with other apparatus; Adaptations of gas-turbine plants for special use using the waste heat of gas-turbine plants outside the plants themselves, e.g. gas-turbine power heat plants

Abstract

Inflammatory bowel disease (IBD) in humans and dogs and other companion animals is characterized by infiltration of lymphocytes and macrophages into the mucosa and submucosa and clinical signs of gastrointestinal (Gl) dysfunction (diarrhea, malabsorption, weight loss). Alteration of the gut environment and development of dysbiosis may allow the overgrowth of pathogenic bacteria and induction of intestinal injury and inflammation in IBD. What is needed are novel methods that allow for rapid diagnosis of IBD (and follow-up monitoring) and treatment of the disease. The present disclosure relates to methods for diagnosing and treating inflammatory bowel disease (IBD) or gastrointestinal lymphoma.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
• C12Q 1/6813 - Hybridisation assays
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Abstract

A method may include receiving video data that includes frames representative of infrared radiation within a scene. Each of the frames may include pixels The method may also include identifying pixels within the frames that correspond to a gas plume released by a gas source within the scene based on the infrared radiation. In addition, the method may include determining a size of the gas plume within each frame based on the identified pixels.

IPC Classes  ?

• G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
• G01J 5/00 - Radiation pyrometry, e.g. infrared or optical thermometry

Abstract

An ultra-efficient turbo-compression cooling system links an organic Rankine power cycle and a vapor compression cooling cycle using a turbine and compressor that shares a single shaft and further linked to an evaporative condenser. The power cycle implements a waste heat exchanger configured to evaporate a working fluid and a turbine configured to receive the evaporated working fluid. The turbine has a plurality of vanes disposed around a central shaft and configured to rotate as the working fluid expands to a lower pressure within the turbine. An evaporative condenser then condenses the working fluid to a saturated liquid and a mechanical pump pumps the saturated liquid to reenter the waste heat waste heat exchanger. The cooling cycle implements a compressor configured to increase the pressure of the working fluid, with the evaporative condenser (shared with the power cycle) configured to condense the working fluid to a saturated liquid upon exiting the compressor, an expansion valve wherein the working fluid expands to a lower pressure, and an evaporator rejecting heat from a circulating fluid to the working fluid, thereby cooling the circulating fluid.

IPC Classes  ?

• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F01K 11/02 - Steam engine plants characterised by the engines being structurally combined with boilers or condensers the engines being turbines
• F01K 25/10 - Plants or engines characterised by use of special working fluids, not otherwise provided for; Plants operating in closed cycles and not otherwise provided for using special vapours the vapours being cold, e.g. ammonia, carbon dioxide, ether
• F01D 17/14 - Final actuators arranged in stator parts varying effective cross-sectional area of nozzles or guide conduits
• F25B 27/02 - Machines, plants or systems, using particular sources of energy using waste heat, e.g. from internal-combustion engines
• F25B 9/00 - Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point
• F25B 1/10 - Compression machines, plants or systems with non-reversible cycle with multi-stage compression

Abstract

∞∞∞∞ loopshaping and optimizes based on one or more second performance metrics that may include one or more of the first performance metrics.

IPC Classes  ?

• G05B 13/02 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
• G06F 1/26 - Power supply means, e.g. regulation thereof

Abstract

e.g.,Mycobacterium bovis e.g.,e.g., coronavirus).

IPC Classes  ?

• A61K 39/215 - Coronaviridae, e.g. avian infectious bronchitis virus
• A61K 39/04 - Mycobacterium, e.g. Mycobacterium tuberculosis
• A61K 39/12 - Viral antigens
• A61K 35/66 - Microorganisms or materials therefrom
• A61K 35/74 - Bacteria

Abstract

Non-sewered toilet system and method for separation and treatment of human waste are described. The system can include a frontend system with a solids separator (100), a buffer tank separation system (200), a liquid waste treatment system (300), and a solids waste treatment system (500). The solids separator can separate combined human waste including feces or urine into a separated solids portion and a separated liquid portion. The buffer tank separation system can deliver a solids portion of the input stream to the solids collection tank and deliver the liquids portion to the liquids collection tank. The liquid waste treatment system can receive liquid waste collected in the liquids collection tank and deliver a usable water. The solids waste treatment system can receive a slurry from the solids collection tank, heat the slurry to inactivate pathogens, and form feces cakes with a filter press. A combustor can reduce the feces cakes to ash.

IPC Classes  ?

• C02F 9/00 - Multistage treatment of water, waste water or sewage
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• C02F 1/74 - Treatment of water, waste water, or sewage by oxidation with air
• C02F 11/121 - Treatment of sludge; Devices therefor by de-watering, drying or thickening by mechanical de-watering
• C02F 11/123 - Treatment of sludge; Devices therefor by de-watering, drying or thickening by mechanical de-watering using belt or band filters
• C02F 11/128 - Treatment of sludge; Devices therefor by de-watering, drying or thickening by mechanical de-watering using batch processes
• C02F 11/16 - Treatment of sludge; Devices therefor by de-watering, drying or thickening using drying or composting beds
• C02F 11/18 - Treatment of sludge; Devices therefor by thermal conditioning
• C02F 11/06 - Treatment of sludge; Devices therefor by oxidation
• C02F 11/122 - Treatment of sludge; Devices therefor by de-watering, drying or thickening by mechanical de-watering using filter presses
• E03D 1/14 - Cisterns discharging variable quantities of water
• E03D 5/014 - Special constructions of flushing devices combined with movable closure elements in the bowl outlet with devices for separate removal of liquids and solids
• E03D 11/11 - Bowls combined with a reservoir, e.g. containing apparatus for disinfecting or for disintegrating
• B01D 33/04 - Filters with filtering elements which move during the filtering operation with filtering bands or the like supported on cylinders which are impervious for filtering
• B01D 29/35 - Self-supporting filtering elements arranged for outward flow filtration
• B01D 61/02 - Reverse osmosis; Hyperfiltration
• B01D 61/14 - Ultrafiltration; Microfiltration
• B01D 61/16 - Feed pretreatment
• B01D 61/58 - Multistep processes
• B01D 29/90 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups ;   Filtering elements therefor having feed or discharge devices for feeding
• E03F 1/00 - Methods, systems, or installations for draining-off sewage or storm water
• C02F 1/20 - Treatment of water, waste water, or sewage by degassing, i.e. liberation of dissolved gases

Abstract

Various systems and methods for two-chamber combustion system are described. The system includes a combustion section (102) comprising a containment wall (122), a first combustion chamber (110), and a second combustion chamber (112). The first combustion chamber is positioned beneath the second combustion chamber and configured to receive a first fuel. The second combustion chamber configured to receive a second fuel comprising feces. The system also including an exhaust duct (106), a reducer (118) connecting the combustion section to the exhaust duct, and an exhaust vent (108) connected to the exhaust duct at an end opposite the combustion section and at a top of the combustor.

IPC Classes  ?

• F23G 7/00 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of specific waste or low grade fuels, e.g. chemicals
• F23B 10/00 - Combustion apparatus characterised by the combination of two or more combustion chambers
• F23B 60/02 - Combustion apparatus in which the fuel burns essentially without moving with combustion air supplied through a grate

Abstract

A system for generating steam for industrial heat. The system may include a plurality of heat pump cycles in thermal communication with each other and in thermal communication with a steam generation cycle. The plurality of heat pump cycles may include first and second heat pump cycles. The first heat pump circulates a first a working fluid and includes a first heat exchanger. The second heat pump cycle circulates a second working fluid and includes a second heat exchanger. The first heat exchanger transfers heat from the first to the second working fluid. The second heat exchanger transfers heat to a third working fluid in the steam generation cycle.

IPC Classes  ?

• F25B 7/00 - Compression machines, plants or systems, with cascade operation, i.e. with two or more circuits, the heat from the condenser of one circuit being absorbed by the evaporator of the next circuit
• F22B 1/00 - Methods of steam generation characterised by form of heating method
• F25B 11/04 - Compression machines, plants or systems, using turbines, e.g. gas turbines as expanders centrifugal type
• F25B 25/02 - Compression-sorption machines, plants, or systems
• F25B 27/00 - Machines, plants or systems, using particular sources of energy
• F25B 30/02 - Heat pumps of the compression type
• F25B 31/02 - Compressor arrangements of motor-compressor units
• F25B 9/00 - Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point

Abstract

The present disclosure provides compositions and methods related to the treatment of non-tuberculous mycobacterial infections in a subject. In particular, the present disclosure provides compositions comprising an anti-malarial agent and associated methods of treating and/or preventing a non-tuberculous mycobacterial infection in a subject using the composition.

IPC Classes  ?

• A61K 31/357 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 31/08 - Antibacterial agents for leprosy

Abstract

The present application relates to vanadium compounds. More specifically, the present application relates to pharmaceutical compositions comprising vanadium salts, use thereof and methods using the same. The present application also includes compositions comprising vanadium compounds and a therapeutic or prophylactic virus providing for increased virus infection, spread, titer, activity, cytotoxicity and/or immunotherapeutic activity.

IPC Classes  ?

• A61K 31/555 - Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
• A61K 33/24 - Heavy metals; Compounds thereof
• A61K 35/76 - Viruses; Subviral particles; Bacteriophages
• A61K 35/761 - Adenovirus
• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61P 35/00 - Antineoplastic agents
• A61P 37/04 - Immunostimulants
• C07F 9/00 - Compounds containing elements of Groups 5 or 15 of the Periodic System
• C07F 9/06 - Phosphorus compounds without P—C bonds

Abstract

Disclosed herein are methods of carbon sequestration using microorganisms, such as soil microorganisms, capable of synthesizing or consuming degradation-resistant L-carbohydrates. In particular, methods of identifying and using microorganisms capable of synthesizing L-carbohydrates are provided, wherein microorganisms that synthesize L-carbohydrates are contacted with a soil source to sequester carbon. Also provided are methods of identifying and incorporating biomolecules such as genes, peptides, and enzymes relevant for L-carbohydrate anabolism or catabolism into plants so the plants synthesize L-carbohydrates or do not consume L-carbohydrates, thereby sequestering carbon.

IPC Classes  ?

• C05G 3/80 - Soil conditioners
• C12P 19/02 - Monosaccharides
• C12N 15/00 - Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
• C12N 15/01 - Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
• C12N 15/09 - Recombinant DNA-technology
• C12N 15/52 - Genes encoding for enzymes or proenzymes

Abstract

The present disclosure relates to a laser diode system. The system may have at least one laser diode emitter having a substrate, at least one laser diode supported on the substrate, and a facet which a laser beam generated by the laser diode is emitted. A cooling subsystem is included which is disposed in contact with the substrate of the laser diode emitter. The cooling subsystem includes a plurality of cooling fins forming a plurality of elongated channels for circulating a cooling fluid therethrough to cool the laser diode emitter. The cooling fluid also flows over the facet of the laser diode emitter.

IPC Classes  ?

• H01S 5/024 - Arrangements for thermal management

Abstract

A method for fabricating a bone-regeneration scaffold may include providing a printing material including a biologically-derived bone powder, and fabricating, via a 3D printer, the bone-regeneration scaffold using the printing material.

IPC Classes  ?

• A61L 27/14 - Macromolecular materials
• A61L 27/22 - Polypeptides or derivatives thereof
• A61L 27/56 - Porous or cellular materials

Abstract

The present invention relates to a multilayer coating system present on a substrate and comprising at least three coating layers (L1, L2 and L3) being different from one another, namely a first pigmented coating layer (L1) applied over at least a portion of the substrate, a second coating layer (L2) applied over the first pigmented coating layer (L1), and a third coating layer (L3) applied over the second coating layer (L2), wherein the second coating layer (L2) is formed from a coating composition comprising at least one block copolymer containing a backbone and at least two blocks (B1 and B2) and side chains (S1 and S2) comprising different polymeric moieties (M1 and M2), a method of preparing said multilayer coating system, a coated substrate obtainable therefrom, and a use of a coating composition comprising the block copolymer for improving, in particular for increasing, the chromaticity of the inventive multilayer coating system.

IPC Classes  ?

• C08G 61/08 - Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes only aliphatic carbon atoms prepared by ring-opening of carbocyclic compounds of carbocyclic compounds containing one or more carbon-to-carbon double bonds in the ring
• C08L 65/00 - Compositions of macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain; Compositions of derivatives of such polymers
• C09D 165/00 - Coating compositions based on macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain; Coating compositions based on derivatives of such polymers

Abstract

The present invention relates to a multilayer coating system present on a substrate and comprising at least two coating layers L1 and L2 being different from one another, namely a first coating layer L1 applied over at least a portion of the substrate, and a second topcoat layer L2 applied over the first coating layer L1, wherein the topcoat layer L2 is formed from a coating composition comprising at least one block copolymer containing a backbone and at least two blocks B1 and B2 and side chains S1 and S2 comprising different polymeric moieties M1 and M2, a method of preparing said multilayer coating system, a coated substrate obtainable therefrom, and a use of a coating composition comprising the block copolymer for improving, in particular for increasing, the chromaticity of the inventive multilayer coating system.

IPC Classes  ?

• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• C08F 8/02 - Alkylation
• C08F 222/40 - Imides, e.g. cyclic imides
• C08F 267/10 - Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated polycarboxylic acids or derivatives thereof as defined in group on to polymers of amides or imides
• C08F 285/00 - Macromolecular compounds obtained by polymerising monomers on to preformed graft polymers
• C08F 287/00 - Macromolecular compounds obtained by polymerising monomers on to block polymers
• C08F 299/00 - Macromolecular compounds obtained by interreacting polymers involving only carbon-to-carbon unsaturated bond reactions, in the absence of non-macromolecular monomers
• C08G 61/02 - Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
• C08G 63/08 - Lactones or lactides
• C08G 81/02 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
• G02B 1/00 - Optical elements characterised by the material of which they are made; Optical coatings for optical elements

Abstract

Embodiments of the present invention generally relate to compositions and methods for treating acute or chronic bacterial infections of joints, tendons, ligaments, implants and associated soft tissues. In other embodiments, compositions of use herein generally relate to activated MSCs or iMSCs combined with antibiotics having reduced cytotoxicity for the treatment of bacterial infections of joints, tendons, ligaments, implants and associated soft tissue structures.

IPC Classes  ?

• A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution
• A61K 35/12 - Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
• A61K 35/28 - Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• A61P 31/04 - Antibacterial agents

Abstract

Disclosed are various synthetic methods to prepare structural analogs of largazole and derivatives thereof. One structural analog is an amide isostere of largazole. Another structural analog replaces the thiazole ring of largazole with a pyridine moiety or an oxazole moiety. Also disclosed are various intermediate compounds obtained when preparing structural analogs of largazole and derivatives thereof, including macrocycle analogs having an alcohol functionality.

IPC Classes  ?

• A61K 31/429 - Thiazoles condensed with heterocyclic ring systems
• C07D 498/18 - Bridged systems
• C07D 513/18 - Bridged systems

Abstract

Compositions and methods for enhancing the resistance of plants to a disease caused by a bacterial pathogen are provided. The compositions comprise nucleic acid molecules encoding protease inhibitor gene products and variants thereof and plants, seeds, and plant cells comprising such nucleic acid molecules. The methods for enhancing the resistance of a plant to a disease caused by a bacterial pathogen comprise introducing a nucleic acid molecule encoding a protease inhibitor gene product into a plant cell. Additionally provided are antimicrobial compositions containing one or more protease inhibitor proteins for controlling antimicrobial growth on plants or plant parts, and methods for controlling or preventing the growth of microbial pathogens, and in particular bacterial pathogens, on plants and plant parts.

IPC Classes  ?

• A01H 1/00 - Processes for modifying genotypes
• C12N 15/31 - Genes encoding microbial proteins, e.g. enterotoxins
• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

Abstract

The present disclosure relates to data storage systems and methods of making thereof. Aspects of the disclosure further relate to engineered porous protein crystals that bind and adsorb guest information storage mediums such as DNA.

IPC Classes  ?

• C07K 14/00 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
• C30B 29/58 - Macromolecular compounds
• G06N 3/00 - Computing arrangements based on biological models

Abstract

A power plant system is disclosed. The power plant system includes a combustor configured, a turbine configured to generate electricity, a heat exchanger and a steam turbine, a carbon capture system configured to remove at least a portion of carbon-based gasses from the flue gas downstream from the heat recovery steam generator, and a thermal storage system including a hot storage unit configured to store thermal energy at a hot temperature, the hot temperature greater than ambient temperature. The power plant is configured to operate in at least a first mode for storing thermal energy in the thermal storage system and a second mode for releasing the stored thermal energy from the thermal storage system and during the second mode, heat stored in the hot storage unit is transferred to the carbon capture system.

IPC Classes  ?

• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F01K 17/02 - Use of steam or condensate extracted or exhausted from steam engine plant for heating purposes, e.g. industrial, domestic

Abstract

spsp 2spsp 3 phosphorus ligand-coupling, an underdeveloped manifold for C–C bond formation.

IPC Classes  ?

• A61K 31/4196 - 1,2,4-Triazoles
• A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
• A61K 31/4427 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems

Abstract

The present invention relates to specific herbicide combinations comprising (i) glufosinate/L-glufosinate and/or salts thereof and (ii) a mixture of (A) saflufenacil and (B) trifludimoxazin in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 43/54 - 1,3-Diazines; Hydrogenated 1,3-diazines
• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/84 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
• A01P 13/00 - Herbicides; Algicides

Abstract

A biocompatible implant, as well as method of fabricating the implant and repairing an annular defect in annulus fibrosus (AF) of an intervertebral disc (IVD) disposed in a functional spinal unit (FSU), includes an insert that provides faces that can interface with the defect to repair or treat the AF. The implant can deliver biological and mechanical factors to enhance healing in an annular defect and prevent recurrence of herniation symptoms. The implant can be fabricated using a hybrid of first fibrous scaffold structure including at least a first layer and a second layer of first fibers fabricated via three-dimensional fiber deposition (3FD) and second fibrous scaffold structure including a third layer and a fourth layer of second fibers formed via melt electrowriting (MEW). Suitable attachment methods, including bio-adhesives can be used to bond the implant to the IVD and/or FSU.

IPC Classes  ?

• A61F 2/02 - Prostheses implantable into the body
• A61F 2/30 - Joints
• A61F 2/44 - Joints for the spine, e.g. vertebrae, spinal discs

Abstract

Mycobacterium tuberculosisMycobacterium tuberculosis. Vaccine compositions comprising inactivated microbes, and methods of use thereof, are also provided.

IPC Classes  ?

• A61K 31/525 - Isoalloxazines, e.g. riboflavins, vitamin B2
• A61K 39/04 - Mycobacterium, e.g. Mycobacterium tuberculosis
• A61K 41/10 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61P 31/06 - Antibacterial agents for tuberculosis
• A61P 31/12 - Antivirals

Abstract

ADADAD) with a single scan during fruit growth and development in the field. The impact of preharvest factors such as crop load and canopy position on peach quality and maturity can be evaluated across a variety of peach cultivars using this novel technology.

IPC Classes  ?

• G01J 3/06 - Scanning arrangements
• G01J 3/42 - Absorption spectrometry; Double-beam spectrometry; Flicker spectrometry; Reflection spectrometry
• G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
• G01N 21/29 - Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using visual detection
• G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light

Abstract

The present disclosure relates to a plant or plant part comprising a polynucleotide encoding a CYP81E polypeptide, the expression of the polynucleotide confers to the plant or plant part tolerance to synthetic auxin herbicides, such as 2,4-D. The disclosure further provides kits for identifying herbicide resistant plants and methods for determining whether a plant is herbicide resistant.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

Abstract

A microfluidic device includes a device body defining a microfluidic pathway including a first channel, a second channel downstream of the first channel, and a junction including a transition between the first channel and the second channel. The transition is configured to inhibit fluid entering the transition from the first channel from forming a meniscus across the second channel, thereby inhibiting capillary-driven flow into the second channel. The microfluidic device further includes a valve that, when activated while capillary-driven flow of the fluid is inhibited at the transition, induces capillary-driven flow through the second channel by facilitating formation of the meniscus.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
• B01J 19/00 - Chemical, physical or physico-chemical processes in general; Their relevant apparatus
• B81B 1/00 - Devices without movable or flexible elements, e.g. microcapillary devices
• B81B 3/00 - Devices comprising flexible or deformable elements, e.g. comprising elastic tongues or membranes
• F16K 99/00 - Subject matter not provided for in other groups of this subclass
• G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis

Abstract

An assay device includes an electrochemical testing assembly having a test channel including a capture reagent selected to capture a target analyte and an electrode having a surface in communication with the test channel. The assay device further includes a microfluidic network in communication with the test channel, a buffer fluid inlet in communication with the microfluidic network, and a detection reagent disposed within the microfluidic network. When a buffer fluid is provided to the buffer fluid inlet, the buffer fluid transports the detection reagent to the test channel by capillary-driven flow, and wherein the electrode is configured to measure an electrical response indicating capture of the target analyte by the capture reagent after transportation of the detection reagent to the test channel.

IPC Classes  ?

• G01N 27/327 - Biochemical electrodes
• G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
• G01N 27/30 - Electrodes, e.g. test electrodes; Half-cells
• G01N 27/416 - Systems

Abstract

An assay device includes a colorimetric testing assembly including a detection area, a fluid inlet, and a microfluidic network including a first path extending to the detection area and a second path extending to the detection area. When a fluid (e.g., a buffer fluid or a combined buffer and sample solution) is provided to the fluid inlet, a first portion of the fluid rehydrates a first dried reagent (e.g., a dried enzyme label) disposed along the first path to produce a first rehydrated reagent and a second portion of the fluid rehydrates a second dried reagent (e.g., a dried substrate) to produce a second rehydrated reagent. The first rehydrated reagent and the second rehydrated reagent are then sequentially delivered to the detection area by capillary-driven flow to perform the assay.

IPC Classes  ?

• G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
• G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
• G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
• G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis

Abstract

Disclosed herein are systems and methods to perform hybridized transmission switching of an electric power system to avoid exceeding line ratings and minimize load shedding.

IPC Classes  ?

• G06F 1/28 - Supervision thereof, e.g. detecting power-supply failure by out of limits supervision
• H02J 13/00 - Circuit arrangements for providing remote indication of network conditions, e.g. an instantaneous record of the open or closed condition of each circuitbreaker in the network; Circuit arrangements for providing remote control of switching means in a power distribution network, e.g. switching in and out of current consumers by using a pulse code signal carried by the network

Abstract

Electrodeposition of pure phase SnSb from equimolar quantities of Sn(II) and Sb(III) chlorides in an eutectic ethaline solution on a conducting metal substrate, for use as a sodium-ion battery anode or a lithium ion battery anode, without the need for binders, carbon additives, or post-processing is described.

IPC Classes  ?

• H01M 4/52 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodes; Lithium-ion batteries
• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx

Abstract

Various implementations include a biomass dehydration system including a wet biomass chamber containing wet biomass, a belt or chain defining one or more cavities, two or more pulleys including a drive pulley that the belt or chain extend around and that are configured such that the cavities are disposable within the wet biomass chamber as the belt or chain moves along the pulleys to cause wet biomass to enter the cavities, and a drying chamber for dehydrating wet biomass disposed in the cavities into solid pellets. The drive pulley engages the belt or chain and causes the belt or chain to move around the pulleys. At least a portion of the belt or chain extends from the wet biomass chamber through the drying chamber. One of the pulleys includes one or more ejection protrusions for engaging the cavities and ejecting solid pellets from the cavities.

IPC Classes  ?

• F26B 15/22 - Machines or apparatus for drying objects with progressive movement; Machines or apparatus with progressive movement for drying batches of material in compact form with movement in a path composed of one or more straight lines, e.g. compound the lines being all vertical or steeply inclined the objects or batches of materials being carried by endless belts
• F26B 15/18 - Machines or apparatus for drying objects with progressive movement; Machines or apparatus with progressive movement for drying batches of material in compact form with movement in a path composed of one or more straight lines, e.g. compound the lines being all horizontal or slightly inclined the objects or batches of materials being carried by endless belts
• F26B 21/00 - Arrangements for supplying or controlling air or gases for drying solid materials or objects
• F26B 23/04 - Heating arrangements using electric heating
• F26B 25/00 - DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM - Details of general application not covered by group or

Abstract

LactobacillusLactobacillus) engineered to express immunogenic polypeptides and immunogenicity-enhancing adjuvant polypeptides to treat and/or prevent infection from a pathogenic organism (e.g., coronavirus).

IPC Classes  ?

• A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
• A61K 35/66 - Microorganisms or materials therefrom
• A61K 35/74 - Bacteria
• A61K 38/00 - Medicinal preparations containing peptides
• A61K 38/16 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
• A61K 38/19 - Cytokines; Lymphokines; Interferons

Abstract

A device for emitting photons into a fluid is disclosed. The device includes a fluid channel configured to transfer the fluid from an inlet to an outlet thereof and the fluid channel having a helical pathway wound about a longitudinal axis. The device also includes at least one inner light source adjacent the fluid channel, the at least one inner light source positioned between the fluid channel and the longitudinal axis and at least one outer light source adjacent the fluid channel, the fluid channel positioned between the outer light source and the longitudinal axis.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
• A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
• A61N 5/06 - Radiation therapy using light
• C12N 1/12 - Unicellular algae; Culture media therefor

Abstract

The invention discloses a method and a system to detect a target nucleic acid sequence in a sample using padlock probe-based rolling circle amplification and nuclease protection. Padlock probe-based rolling circle amplification and nuclease protection may be used in combination with other detection assays to detect target nucleic acid sequences in a sample.

IPC Classes  ?

• C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
• C12Q 1/682 - Signal amplification

Abstract

e.ge.g., inactivated SARS-CoV-2 particles) are also provided. In some embodiments, the vaccine compositions comprise an adjuvant capable of promoting a Th1-type immune response.

IPC Classes  ?

• A61K 39/12 - Viral antigens
• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61P 31/14 - Antivirals for RNA viruses
• G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups

Abstract

Various implementations include a combustor system including an inner wall, a fuel grate, an ash grinder, an igniter, and a fan. The inner wall defines a combustion chamber and has a longitudinal axis and first and second ends. The inner wall defines primary and secondary air inlets. The primary air inlets are defined closer than the secondary air inlets to the first end. The fuel grate is disposed within the combustion chamber between the primary and secondary air inlets and is configured to support fuel disposed within the combustion chamber. The ash grinder is disposed between the fuel grate and the secondary air inlets and is rotatable about the longitudinal axis relative to the fuel grate. The igniter provides energy to the combustion chamber. The fan is configured to cause air to flow from the primary and secondary air inlets through the second end of the combustion chamber.

IPC Classes  ?

• F23G 5/46 - Recuperation of heat
• F23B 99/00 - Subject matter not provided for in other groups of this subclass
• F23G 5/00 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels

Abstract

An impingement cooling device including a distributor plate, a manifold, and a heat spreader. The distributor plate includes a first side, a second side opposite the first side, a plurality of injection ports extending through the distributor plate from the first side to the second side, and a plurality of extraction ports extending through the distributor plate from the first side to the second side. The manifold is coupled to the distributor plate and includes a partition wall separating the plurality of injection ports and the plurality of extraction ports on the first side. The heat spreader at least partially covers an object to be cooled and includes a top surface configured to oppose the second side of the distributor plate. The heat spreader further includes a surface feature on the top surface configured to increase heat transfer therefrom.

IPC Classes  ?

• H01L 23/467 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing gases, e.g. air
• H01L 23/473 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing liquids

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) flumiclorac-pentyl in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 39/04 - Aryloxy-acetic acids; Derivatives thereof
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) carfentrazone-ethyl in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/653 - 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) flumioxazin in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/84 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) epyrifenacil (Acetic acid, 2-[[3-[2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl]-4-fluorophenoxy]-2-pyridinyl]oxy]-, ethyl ester) in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or unde-sired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/54 - 1,3-Diazines; Hydrogenated 1,3-diazines
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) sulfentrazone in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/653 - 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) tiafenacil in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/54 - 1,3-Diazines; Hydrogenated 1,3-diazines
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) a PPO-inhibitor selected from Acifluorfen, Fomesafen or Lactofen in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 37/48 - Nitro-carboxylic acids; Derivatives thereof
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) a PPO-inhibitor selected from Cyclopyranil, Oxadiargyl, Pentoxazone or Pyraclonil in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/90 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
• A01N 43/82 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms five-membered rings with three hetero atoms
• A01N 43/76 - 1,3-Oxazoles; Hydrogenated 1,3-oxazoles
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) saflufenacil in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/54 - 1,3-Diazines; Hydrogenated 1,3-diazines
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) fluthiacet-methyl in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/90 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) pyraflufen-ethyl in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/56 - 1,2-Diazoles; Hydrogenated 1,2-diazoles
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) trifludimoxazin in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/84 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) oxyfluorfen in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 33/22 - Nitro compounds containing oxygen or sulfur attached to the carbon skeleton containing the nitro group having at least one oxygen or sulfur atom and at least one nitro group directly attached to the same aromatic ring system
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) oxadiazon in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/82 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms five-membered rings with three hetero atoms
• A01P 13/00 - Herbicides; Algicides

Abstract

ghighi]perylene imide photoredox catalysts (PC) and methods for the Birch reductions of aromatic substrates, such as benzene, benzeneoid, and heteroaromatic compounds, using light as the driving force. Certain aspects of the disclosure encompass methods for reduction of aromatic substrates. The method comprises contacting an aromatic substrate with a sacrificial electron donor in the presence of a photoredox catalyst in a solvent, thereby forming a reaction mixture; exposing the reaction mixture to visible or UV light under reaction condition sufficient to reduce the aromatic substrate compound.

IPC Classes  ?

• B01J 31/00 - Catalysts comprising hydrides, coordination complexes or organic compounds
• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• C07D 209/58 - [b]- or [c]-condensed

Abstract

Phenothiazine compounds of Formula (I) are described herein. These compounds are useful as highly reducing organic photoredox catalysts. Suitable substrates for use with the compounds of Formula (I) include acrylates, styrene, acrylamides, acrylonitrile, vinyl chloride, methylacrylonitrile, vinyl acetate, and acrylic acid.

IPC Classes  ?

• A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
• A61K 31/545 - Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula , e.g. cephalosporins, cefaclor, cephalexine
• A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone

Abstract

Aspects of the present disclosure include a system for turbo-compression cooling. The system may be aboard a marine vessel. The system includes a power cycle and a cooling cycle. The power cycle includes a first working fluid, a waste heat boiler configured to evaporate the working fluid, a turbine, and a condenser. The condenser condenses the working fluid to a saturated or subcooled liquid. The cooling cycle includes a second working fluid, a first compressor configured to increase the pressure of the second working fluid, a condenser configured to condense the second working fluid to a saturated or subcooled liquid after exiting the first compressor, an expansion valve, and an evaporator. The turbine and first compressor are coupled one to the other. The waste heat boiler receives waste heat from engine jacket water and lubricating oil from a ship service generator. The evaporator cools water in a shipboard cooling loop.

IPC Classes  ?

• F01K 7/16 - Steam engine plants characterised by the use of specific types of engine; Plants or engines characterised by their use of special steam systems, cycles or processes; Control means specially adapted for such systems, cycles or processes; Use of withdrawn or exhaust steam for feed-water heating the engines being only of turbine type
• F01K 11/02 - Steam engine plants characterised by the engines being structurally combined with boilers or condensers the engines being turbines
• F01K 17/04 - Use of steam or condensate extracted or exhausted from steam engine plant for specific purposes other than heating
• F01K 25/08 - Plants or engines characterised by use of special working fluids, not otherwise provided for; Plants operating in closed cycles and not otherwise provided for using special vapours
• F25B 9/00 - Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point
• F25B 27/00 - Machines, plants or systems, using particular sources of energy
• F25B 25/00 - Machines, plants or systems, using a combination of modes of operation covered by two or more of the groups

Abstract

An endoprosthesis (300) including a scapular fixation (302) for attaching to the scapula (202), a humeral fixation (304) insertable in the medullary cavity (208) of a distal portion of the humerus (212) after the proximal portion thereof (210)has been excised, and a joint replica (306) extending therebetween.In some embodiments, the joint replica (306) is articulated. Also, an implant (300)including a textured muscle attachment zone (324,326,328).

IPC Classes  ?

• A61F 2/28 - Bones
• A61B 17/15 - Guides therefor
• A61B 17/17 - Guides for drills
• A61B 17/56 - Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
• A61F 2/30 - Joints

Abstract

Methods for detecting a mycobacterial infection in a patient are disclosed. These methods include the step of detecting lipoarabinomannan (LAM) and/or derivatives thereof in a biological sample from the patient. Methods for diagnosing disease, including nontuberculous mycobacterial infection (NTM), and kits for the described methods are also provided.

IPC Classes  ?

• G01N 33/569 - Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
• G01N 33/92 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol

Abstract

A portable sampler, the sampler including a sampler assembly having a housing that includes a receiver defined therein for interchangeably receiving a number of removable inlet assemblies, the removable inlet assemblies including a respirable inlet assembly and a thoracic inlet assembly. The respirable inlet assembly includes a hybrid cyclone assembly, the hybrid cyclone assembly including an impaction stage and a cyclone in series. The thoracic inlet assembly includes an inlet slot configured to function as a size-selective inlet. Another thoracic inlet assembly includes a housing having a number of openings configured to receive a sample airflow; an inlet insert through which an inlet aperture is defined; a prequalification chamber defined between a lower surface of the housing and an upper surface of the inlet insert; and a protrusion extending downward from the lower surface of the housing into the inlet aperture of the inlet insert to from an inlet slot.

IPC Classes  ?

• G01N 1/22 - Devices for withdrawing samples in the gaseous state
• G01N 15/06 - Investigating concentration of particle suspensions
• A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements

Abstract

A monomer design strategy based on a bridged bicyclic thiolactone that produces stereo-disordered to perfectly stereo-ordered polythioesters is disclosed. The described polythioesters exhibit high crystallinity and full chemical recyclability. Such polymers possess intrinsic tacticity-independent crystallinity and chemical recyclability, tunable tacticities from stereo-disorder to perfect stereoregularity, as well as combined high-performance properties such as high thermal stability and crystallinity, and high mechanical strength, ductility and toughness.

IPC Classes  ?

• C08G 75/26 - Polythioesters
• C08G 63/08 - Lactones or lactides
• C07D 495/00 - Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms

Abstract

32 2 or an organic phenoxazine. In certain embodiments, the Ni salt catalyst solution includes a Ni(II) salt and a polar solvent, wherein the Ni(II) salt is dissolved in the polar solvent.

IPC Classes  ?

• C07D 295/073 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Abstract

Embodiments of the present invention generally relate to novel immunostimulatory compositions of use to stimulate non-specific immune responses in a subject. In certain embodiments, immunogenic compositions disclosed herein can be directed to use in the eye of a subject. In some embodiments, the immunogenic compositions disclosed herein enhance non-specific immune responses in the eye of a subject to treat or reduce the risk of onset of an eye condition. In other embodiments, compositions disclosed herein can be used to treat eye infections due to a microorganism, tumors of the eye, as well as, chronic wounds or infections of the eye. In some embodiments, immunogenic ocular formulations disclosed herein include combinations of agents for prolonged exposure to the eye for improved outcomes.

IPC Classes  ?

• A61K 9/127 - Liposomes
• A61K 9/51 - Nanocapsules
• A61K 38/17 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans
• A61P 27/02 - Ophthalmic agents

Abstract

In certain embodiments, a portable atmospheric monitor comprises a housing at least partially enclosing an inner chamber. The housing comprises an inlet and an aperture. The monitor also includes at least one light sensor arranged within the housing. The light sensor that senses one or more wavelengths of sunlight received via the aperture. The monitor includes at least one light-scattering sensor that senses PM received via the inlet. The monitor includes a processor arranged within the housing and coupled to the at least one light sensor and the at least one light-scattering sensor. The processor is configured to: receive a light signal from the at least one light sensor; receive a PM signal from the at least one light-scattering sensor; determine the aerosol optical depth based upon the light signal; and determine the PM concentration based upon the PM signal.

IPC Classes  ?

• G01N 1/22 - Devices for withdrawing samples in the gaseous state
• G01N 21/53 - Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke

Abstract

The present invention provides photocatalysts, methods for their preparation, and methods for preparing linear polymers with high propagation rate.

IPC Classes  ?

• C07D 219/04 - Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
• C07D 265/38 - [b, e]-condensed with two six-membered rings

Abstract

The present disclosure relates to methods for diagnosing and treating inflammatory bowel disease (IBD) in companion animals.

IPC Classes  ?

• C07K 16/42 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against immunoglobulins (anti-idiotypic antibodies)
• C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
• A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
• A61K 35/74 - Bacteria
• A61K 39/116 - Polyvalent bacterial antigens
• A61K 39/02 - Bacterial antigens
• A61K 39/108 - Escherichia; Klebsiella
• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

Abstract

The present invention refers to a plant or plant part comprising a polynucleotide encoding an herbicide tolerant IAA2 polypeptide having a deleted or disrupted degron tail region, the expression of said polynucleotide confers to the plant or plant part tolerance to synthetic auxin herbicides, such as 2,4-D. The present invention relates to methods and plants and that have a deleted or disrupted degron tail region of the IAA2 protein obtained by gene editing, transformation, mutagenesis, breeding, and the like.

IPC Classes  ?

• A01H 1/04 - Processes of selection
• C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
• A01H 1/00 - Processes for modifying genotypes
• C12N 15/01 - Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

Polymer composite photonic crystal materials are disclosed as coatings which have high reflection (>30%) in a specific range of the electromagnetic spectrum, such as ultraviolet (< 400nm), visible (Vis, 400nm-700nm), or near-infrared radiation range (NIR, 700 - 2000 nm), and relatively low reflection (<20% reflection) in a second, different range of the electromagnetic spectrum. Surprisingly, it was found that through a formulation and additives approach, the optical properties of polymer composite photonic crystal films can be selectively modified from a variety of different coating methods, including spray deposition.

IPC Classes  ?

• C08G 81/02 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers at least one of the polymers being obtained by reactions involving only carbon-to-carbon unsaturated bonds
• C08G 83/00 - Macromolecular compounds not provided for in groups
• C08G 81/00 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers

Abstract

The present invention provides efficient processes for preparing brush polymers. In general, the process comprises three distinct reaction steps utilizing two separate catalysts. In the first step, the initiating compound comprising norbornene is contacted with a silane in the presence of a catalyst, thereby forming a silated intermediate. This silated intermediate is then contacted with a monomer in the presence of a catalyst via Group Transfer Polymerization (GTP). The resulting compound from GTP is contacted with a ring opening metathesis polymerization (ROMP) catalyst to prepare the brush polymer. Surprisingly, the brush polymers obtained from the above process are accessed in an efficient and rapid GTP methodology as compared to prior methods.

IPC Classes  ?

• G02C 7/04 - Contact lenses for the eyes

Abstract

Polymer composite photonic crystal materials are disclosed as coatings and topcoats which have high reflection (>30%) in a specific range of the electromagnetic spectrum, such as ultraviolet (< 400nm), visible (Vis, 400nm-700nm), or near-infrared radiation range (NIR, 700 - 2000 nm), and relatively low reflection (<20% reflection) in a second, different range of the electromagnetic spectrum. Surprisingly, it was found that through a formulation and additives approach, the optical properties of polymer composite photonic crystal films can be selectively modified from a variety of different coating methods, including spray deposition.

IPC Classes  ?

• C08G 81/00 - Macromolecular compounds obtained by interreacting polymers in the absence of monomers, e.g. block polymers
• C08F 222/40 - Imides, e.g. cyclic imides
• G02B 1/00 - Optical elements characterised by the material of which they are made; Optical coatings for optical elements

Abstract

A wedge osteotomy device including a cutting guide coupled to a base plate via a joint. The cutting guide configured to pivot relative to the base plate about a pivot axis extending through the joint. The cutting guide including a guide body including a cutting slot extending through the guide body, an arcuate slot extending through the guide body and defining a radius to the joint, and a plurality of markers on the guide body identifying a position of the cutting guide relative to the base plate. The base plate including planar top and bottom surfaces.

IPC Classes  ?

• A61B 17/15 - Guides therefor
• A61B 17/14 - Surgical saws
• A61B 17/56 - Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor

Abstract

in vivoin vivo, as well as novel scFv's produced therefrom. The disclosed novel scFV's can be used a variety of applications.

IPC Classes  ?

• C07K 16/10 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
• G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor

Abstract

The present document generally relates to additive manufacturing techniques for forming an article having a desired shape and other properties. More particularly, but not exclusively, in one embodiment a method for additive manufacturing an article includes adding a dispersant to an article forming material in the absence of binder to prepare a slurry or suspension including the material and the dispersant. The pH of the slurry may be adjusted to control the viscosity and/or coagulation rate of the slurry. The slurry may then be passed through an extrusion-based three-dimensional printing apparatus to form or print the article in a desired form or shape, and the article may thereafter be sintered. In one aspect, through control of the pH of the slurry, the viscosity and/or coagulation rate properties of the slurry may be tailored for use with different operating parameters of the extrusion-based three-dimensional printing apparatus.

IPC Classes  ?

• B29C 64/10 - Processes of additive manufacturing
• B33Y 10/00 - Processes of additive manufacturing
• B33Y 70/00 - Materials specially adapted for additive manufacturing
• C04B 35/10 - Shaped ceramic products characterised by their composition; Ceramic compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminium oxide
• C04B 35/64 - Burning or sintering processes

Abstract

The disclosure relates to a method for forming aryl carbon-nitrogen bonds and to photoreactors useful in these and other light-driven reactions. The method comprises contacting an aryl halide with an amine in the presence of a Ni salt catalyst solution and an optional base, thereby forming a reaction mixture; exposing the reaction mixture to light under reaction condition sufficient to produce the aryl carbon-nitrogen bonds. In certain embodiments, the amine may be present in a molar excess to the aryl halide. In certain embodiments, the Ni salt catalyst solution includes a Ni(II) salt and a polar solvent, wherein the Ni(II) salt is dissolved in the polar solvent. In certain embodiments, the reactions conditions include holding the reaction mixture at between about room temperature and about 80ºC for between about 1 hour and about 20 hours such that at least about 50% yield is obtained.

IPC Classes  ?

• C07D 209/82 - Carbazoles; Hydrogenated carbazoles
• C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
• C07D 409/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

Enzymes that reduce specific metal or metalloid ions to insoluble form are important to science. Peptides isolated from yeast- and phage-display libraries can affect the size and morphology of inorganic materials during their synthesis. Herein, an Se binding peptide was fused to an enzyme capable of reducing selenite (SeO32-) to a Se0nanoparticle (SeNP). The fusion of the Se binding peptide to the metalloid reductase provided size control of the resulting SeNP. The SeNP product also remains associated to the enzyme fusion. The Se binding peptide fusion to the enzyme increases the enzyme's SeO32- reductase activity. Modification of enzyme activity was absent, and the size control of particles was diminished when the Se binding peptide was added exogenously to the reaction mixture. Binding of the peptide is attributed to His based ligation that results in a conformational change to the peptide.

IPC Classes  ?

• C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
• C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
• G01N 27/327 - Biochemical electrodes
• G01N 33/15 - Medicinal preparations

Abstract

Embodiments herein report compositions, methods, and uses for enhancing the immune system in a subject in need of such modulation/treatment. In certain embodiments, compositions and methods disclosed herein concern compositions that can include, but are not limited to, at least one agent capable of reducing the activation of, or blocking an angiotensin II receptor (ARB) and C-C chemokine receptor 2 (CCR2); and/or blocking a beta receptor (Beta Blocker, BRB), to induce and/or enhance immune response in subject. In certain embodiments, combination agents disclosed herein can enhance an immune response against cancer in a subject in need thereof. In other embodiments, combination therapies disclosed herein modify the tumor microenvironment (TME) to enhance effects of anti-cancer therapies as a combination therapy or used alone to modify the immune system of the subject to treat cancer in a subject.

IPC Classes  ?

• A61K 31/133 - Amines, e.g. amantadine having hydroxy groups, e.g. sphingosine
• A61K 31/4178 - 1,3-Diazoles not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 35/00 - Antineoplastic agents

Abstract

transtrans-fusing of rings to the parent γ-butyrolactone ring. Furthermore, a polymerization or copolymerization process for the synthesis of RF-P4HB polymers and copolymers is disclosed.

IPC Classes  ?

• A61K 31/365 - Lactones
• A61K 47/30 - Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
• A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
• C08G 63/00 - Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
• C08G 63/78 - Preparation processes
• C08G 63/82 - Preparation processes characterised by the catalyst used

Abstract

In some embodiments, an apparatus includes a volatile memory, a non-volatile memory, a first processor coupled to the non-volatile memory and configured to receive a data set associated with an object and user information associated with a spatial position of a user in a multi-user virtual (IMVR) environment, and a second processor coupled to the volatile memory, the second processor configured to render an instance of the portion of the object in the IMVR environment from a perspective of the user based on the spatial position of the user. The first processor is configured to generate a look-up table (LUT) based on a set of inputs received from a user. The second processor is configured to render, based on the LUT and information related to a manipulation by a user, an updated instance of the portion of the object that manifests an effect of the manipulation in the IMVR environment.

IPC Classes  ?

• G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer
• G06T 15/08 - Volume rendering
• G06T 19/00 - Manipulating 3D models or images for computer graphics
• G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
• G16H 30/00 - ICT specially adapted for the handling or processing of medical images

Abstract

An example pump for driving a biological fluid is described herein. The pump can include an inner tubular structure and an outer tubular structure arranged around the inner tubular structure. The outer tubular structure can be configured as an artificial muscle. The pump can also include a gel layer disposed between the inner and outer tubular structures.

IPC Classes  ?

• A61M 1/12 - Blood pumps; Artificial hearts; Devices for mechanical circulatory assistance, e.g. intra-aortic balloon pumps implantable into the body
• A61F 2/08 - Muscles; Tendons; Ligaments
• A61M 1/10 - Blood pumps; Artificial hearts; Devices for mechanical circulatory assistance, e.g. intra-aortic balloon pumps
• F04B 43/04 - Pumps having electric drive
• F04B 43/08 - Machines, pumps, or pumping installations having flexible working members having tubular flexible members
• F04B 43/09 - Pumps having electric drive

Abstract

A portable sampling device includes a sampling housing at least partially enclosing an inner chamber; at least one pumping element disposed within the inner chamber and configured to facilitate airflow through the device; and at least one gas sensor disposed within the inner chamber and configured to detect and/or characterize one or more gases in the airflow.

IPC Classes  ?

• G01N 1/24 - Suction devices
• G01N 1/22 - Devices for withdrawing samples in the gaseous state
• G01N 1/40 - Concentrating samples

Abstract

The present disclosure provides compositions and methods for tracking vegetation through the production and distribution cycle, and for distinguishing between plants or crops having different characteristics.

IPC Classes  ?

• A01G 7/00 - Botany in general
• A01G 9/00 - Cultivation in receptacles, forcing-frames or greenhouses; Edging for beds, lawn or the like
• A01G 22/00 - Cultivation of specific crops or plants not otherwise provided for

Abstract

Systems and methods for generating and tracking molecular digital signatures to ensure authenticity and integrity of NA molecules are disclosed. In some embodiments, a NA authentication system includes a NA authentication device coupled to one or more user devices. Methods for generating a signed NA sequence, validating a signed NA sequence, and detecting/correcting potential errors within a user allowable limit using a NA authentication system are disclosed. Methods for associating a signed NA sequence with a digital representation of the NA sequence, using a NA authentication system, are disclosed

IPC Classes  ?

• G16B 50/40 - Encryption of genetic data

Abstract

A loading device, a monitoring system, and a method thereof can measure stiffness of a structural member (SM), such as a bone, and monitor progress or property over time. The loading device includes two types of displacement sensors, one type being an antenna. As the SM, which is in a magnetic or electromagnetic field and electromagnetically coupled to the antenna without contact, undergoes displacement under known loads, characteristics of the electromagnetic field coupling between the antenna and the SM change over time due to the displacement of the SM. The shift in the characteristics of the electromagnetic field coupling between the antenna and the SM can be used to determine the displacement of the SM. Based on the changes in the displacement over time, diagnosis of the SM being monitored over an evaluation period can be made.

IPC Classes  ?

• A61B 5/103 - Measuring devices for testing the shape, pattern, size or movement of the body or parts thereof, for diagnostic purposes
• G01L 1/00 - Measuring force or stress, in general
• G01M 1/00 - Testing static or dynamic balance of machines or structures
• G01M 5/00 - Investigating the elasticity of structures, e.g. deflection of bridges or aircraft wings
• G01N 3/00 - Investigating strength properties of solid materials by application of mechanical stress
• G01N 3/06 - Special adaptations of indicating or recording means
• G01N 3/20 - Investigating strength properties of solid materials by application of mechanical stress by applying steady bending forces

Abstract

The disclosure provides a cancer vaccine composition comprising inactivated cancer cells and an adjuvant, wherein the inactivated cancer cells are incapable of replication. Also provided is a method for producing a cancer vaccine composition, the method comprising contacting cancer cells with light (e.g., UV light) in the presence of a photosensitizer (e.g., riboflavin).

IPC Classes  ?

• A61K 39/00 - Medicinal preparations containing antigens or antibodies

Abstract

In this work, a hydrophilic, yet slippery solid surface was developed. Because the surfaces are hydrophilic, there is significant affinity between the surface and contacting water, which results in substantial spreading of the contacting liquids on the surface. Due to their strong affinity, a high solid-liquid adhesion having virtually no mobility of the water on the surface occurs. However, counter-intuitively, the disclosed surfaces are highly slippery such that liquids can slide on the surface while maintaining their hydrophilicity. Demonstrated herein are water droplets that can slide on the surface under its own weight, when the hydrophilic, yet slippery solid surface is slightly tilted (ω = 3°). This indicates that the disclosed hydrophilic surfaces are slippery to water.

IPC Classes  ?

• A61L 29/08 - Materials for coatings
• A61L 33/00 - Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
• B05D 3/10 - Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by other chemical means

Abstract

11 + with high field-uniformity, with high efficiency, with excellent circular polarization, with negligible axial z-component, with arbitrary large field of view, and with exceptional possibilities for field-optimizations via RF shimming.

IPC Classes  ?

• A61N 2/06 - Magnetotherapy using magnetic fields produced by permanent magnets

Abstract

A substrate having an antibacterial surface includes a chitosan matrix and water-stable metal-organic frameworks dispersed throughout the chitosan matrix. The water-stable metal-organic frameworks are present in an amount of 5% wt/wt to 20% wt/wt based on total solids of the substrate

IPC Classes  ?

• A01N 55/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
• C08B 37/08 - Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Abstract

Aspects of the present disclosure involve systems, methods, and computer program products for obtaining and displaying a large image file over a network. In one embodiment, a user utilizes a computing device to obtain a large image file over a network, such as the Internet. The large image file may be stored in and available from a network device, such as a application server or database. To obtain the image file, a user interface executed on the user's computing device determines which portions of the overall image file are to be displayed in the interface. The interface may utilize one or more image variables to create or generate one or more network addresses at which the image tiles are stored or otherwise available. To retrieve the image tiles, the computing device uses the generated network addresses of the identified image tiles to request and obtain the image tiles.

IPC Classes  ?

• G06T 1/00 - General purpose image data processing
• G06F 17/30 - Information retrieval; Database structures therefor
• H04L 12/00 - Data switching networks

Abstract

The present disclosure provides a biosignature that distinguishes Lyme disease, including early Lyme disease, from STARI. The present disclosure also provides methods for detecting Lyme disease and STARI, as well as methods for treating subjects diagnosed with Lyme disease or STARI.

IPC Classes  ?

• C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
• G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
• G01N 30/72 - Mass spectrometers
• G01N 33/487 - Physical analysis of biological material of liquid biological material
• G01N 33/569 - Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses