Abstract

There is provided with a method for treating cancer, comprising administering a pharmaceutical composition to a patient with cancer in combination with an anti-cancer agent, the pharmaceutical composition. A compound is represented by General Formula (I) or a pharmaceutically acceptable salt thereof: There is provided with a method for treating cancer, comprising administering a pharmaceutical composition to a patient with cancer in combination with an anti-cancer agent, the pharmaceutical composition. A compound is represented by General Formula (I) or a pharmaceutically acceptable salt thereof: where R1 is an acyl residue from a fatty acid.

IPC Classes  ?

• A61K 31/7028 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
• A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
• A61P 35/00 - Antineoplastic agents

Abstract

A titanium superhydrophobic surface comprising a coating of a perfluorosilane on contiguous titania micrograins surrounded by crevices, the micrograins comprising a topography of nanopits shaped by contiguous peaks and valleys. The superhydrophobic surface has significantly increased hemocompatibility and enhanced antibacterial properties compared to an unmodified titanium surface. The increased hemocompatibility was confirmed by reduced platelet adhesion, reduced leukocyte adhesion, and reduced thrombus formation. The surface is prepared by a facile hydrothermal treatment of a titanium surface with sulfuric acid, leading to the formation of a unique micro-nano surface topography. The superhydrophobic surface was then achieved by coating the micro-nano titanium surface with a low energy silane using physical vapor deposition.

IPC Classes  ?

• A61L 27/30 - Inorganic materials
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 31/08 - Materials for coatings
• A61L 31/10 - Macromolecular materials
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites

Abstract

Disclosed are vanadium (V) compounds and pharmaceutical compositions comprising these vanadium compounds. Also disclosed are methods of making and using these vanadium compounds, for example, to treat cancer (e.g., including brain cancer).

IPC Classes  ?

• C07F 9/00 - Compounds containing elements of Groups 5 or 15 of the Periodic System

Abstract

Disclosed herein are methods of carbon sequestration using microorganisms, such as soil microorganisms, capable of synthesizing or consuming degradation-resistant L-carbohydrates. In particular, methods of identifying and using microorganisms capable of synthesizing L-carbohydrates are provided, wherein microorganisms that synthesize L-carbohydrates are contacted with a soil source to sequester carbon. Also provided are methods of identifying and incorporating biomolecules such as genes, peptides, and enzymes relevant for L-carbohydrate anabolism or catabolism into plants so the plants synthesize L-carbohydrates or do not consume L-carbohydrates, thereby sequestering carbon.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

Abstract

The present disclosure provides a porous elastomer, methods of preparing the porous elastomer, and methods of using the porous elastomers. The porous elastomers described herewith may be hydrophilic and hydrophobic porous elastomers derived from a TPPE precursor composite.

IPC Classes  ?

• C09D 153/00 - Coating compositions based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
• B01D 71/80 - Block polymers
• H01M 50/40 - Separators; Membranes; Diaphragms; Spacing elements inside cells
• H01M 50/403 - Manufacturing processes of separators, membranes or diaphragms

Abstract

Disclosed are various synthetic methods to prepare structural analogs of largazole and derivatives thereof. One structural analog is an amide isostere of largazole. Another structural analog replaces the thiazole ring of largazole with a pyridine moiety or an oxazole moiety. Also disclosed are various intermediate compounds obtained when preparing structural analogs of

IPC Classes  ?

• C07D 513/18 - Bridged systems

Abstract

The present disclosure provides compositions and methods for generating plants that can grow in saline conditions, or remove a salt or other impurity from water, for example plants that can remove sodium chloride from salt or sea water, and plants that can produce purified water from salt or sea water.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C02F 3/32 - Biological treatment of water, waste water, or sewage characterised by the animals or plants used, e.g. algae
• C07K 14/415 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

Abstract

The present disclosure provides methods, kits, and compositions comprising β-alethine and one or more immune modulators and methods to determine when they are advantageous. Particular applications include the use of β-alethine and one or more immune modulators in the treatment of cancer.

IPC Classes  ?

• A61K 31/16 - Amides, e.g. hydroxamic acids
• A61P 35/00 - Antineoplastic agents
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 38/17 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans
• A61K 38/20 - Interleukins
• A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Abstract

This disclosure describes systems, methods, and apparatus for a distributed controller. The distributed controller can include a traditional closed or open loop feedback controller followed by an empirically derived mapping that converts the controller output to a modified output, where the controller optimizes stability and the empirically derived mapping optimizes performance. The empirically derived mapping can be formed of coefficients representing linear controllers at inflection points, where the linear controllers are inversely related to a system model. The system model can comprise a static linear model, a dynamic linear model, and a total uncertainty. The static linear model can be derived from large signal steady state analysis, the dynamic nonlinear model can be derived from small signal transient analysis, and the uncertainty can be derived from small signal steady state analysis.

IPC Classes  ?

• G05B 19/4155 - Numerical control (NC), i.e. automatically operating machines, in particular machine tools, e.g. in a manufacturing environment, so as to execute positioning, movement or co-ordinated operations by means of programme data in numerical form characterised by programme execution, i.e. part programme or machine function execution, e.g. selection of a programme

Abstract

Embodiments of the present invention generally relate to compositions and methods for treating acute or chronic bacterial infections of joints, tendons, ligaments, implants and associated soft tissues. In other embodiments, compositions of use herein generally relate to activated MSCs or iMSCs combined with antibiotics having reduced cytotoxicity for the treatment of bacterial infections of joints, tendons, ligaments, implants and associated soft tissue structures.

IPC Classes  ?

• A61K 35/28 - Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
• A61K 38/14 - Peptides containing saccharide radicals; Derivatives thereof
• A61K 31/43 - Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula , e.g. penicillins, penems
• A61K 31/7056 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
• A61K 31/407 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
• A61K 31/546 - Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula , e.g. cephalosporins, cefaclor, cephalexine containing further heterocyclic rings, e.g. cephalothin
• A61P 31/04 - Antibacterial agents

Abstract

A new set of bench-stable fluoroalkylphosphines that directly convert C—H bonds in pyridine building blocks, drug-like fragments, and pharmaceuticals, into fluoroalkyl derivatives. No pre-installed functional groups or directing motifs are required. The reaction tolerates a variety of sterically and electronically distinct pyridines and is exclusively selective for the 4-position in most cases. The reaction proceeds via initial phosphonium salt formation followed by sp2-sp3 phosphorus ligand-coupling, an underdeveloped manifold for C—C bond formation.

IPC Classes  ?

• C07F 9/572 - Five-membered rings
• C07B 47/00 - Formation or introduction of functional groups not provided for in groups
• C07F 9/50 - Organo-phosphines

Abstract

The present disclosure provides compositions and methods for sensing a target substance of interest in the environment and inducing gene expression in response thereto, useful for detection of biological and chemical agents and environmental pollutants.

IPC Classes  ?

• C07K 14/705 - Receptors; Cell surface antigens; Cell surface determinants
• C12N 15/62 - DNA sequences coding for fusion proteins
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)

Abstract

In accordance with the purposes of the disclosed materials and methods, as embodied and broadly described herein, the disclosed subject matter, in one aspect, relates to a thermoformed polymeric valved conduits for heart valve and methods of using and making thereof. The thermoformed polymeric valved conduits is formed via a thermoforming process that conforms the conduit to a mold; the process forms a conduit that is flexible, resizablke, and/or deformable after being formed.

IPC Classes  ?

• A61F 2/24 - Heart valves
• A61F 2/06 - Blood vessels
• A61F 2/82 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
• A61F 2/958 - Inflatable balloons for placing stents or stent-grafts
• B29C 51/26 - Component parts, details or accessories; Auxiliary operations

Abstract

The present disclosure relates to data storage systems and methods of making thereof. Aspects of the disclosure further relate to engineered porous protein crystals that bind and adsorb guest information storage mediums such as DNA.

IPC Classes  ?

• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• C12Q 1/686 - Polymerase chain reaction [PCR]

Abstract

A power plant system is disclosed. The power plant system includes a combustor configured, a turbine configured to generate electricity, a heat exchanger and a steam turbine, a carbon capture system configured to remove at least a portion of carbon-based gasses from the flue gas downstream from the heat recovery steam generator, and a thermal storage system including a hot storage unit configured to store thermal energy at a hot temperature, the hot temperature greater than ambient temperature. The power plant is configured to operate in at least a first mode for storing thermal energy in the thermal storage system and a second mode for releasing the stored thermal energy from the thermal storage system and during the second mode, heat stored in the hot storage unit is transferred to the carbon capture system.

IPC Classes  ?

• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F01K 15/00 - Adaptations of steam engine plants for special use

Abstract

According to at least one aspect of the present disclosure, a method for grouping constituent flows of a multiplexed or tunneled flow is provided. The method comprises receiving one or more packets of the multiplexed flow; responsive to receiving the one or more packets, determining one or more attributes of the one or more packets of the multiplexed flow; determining, based on the one or more attributes, a predicted state of a next packet of the multiplexed flow; receiving the next packet; responsive to receiving the next packet, determining whether the next packet has an observed state that is similar to the predicted state; and responsive to determining that the observed state is similar to the predicted state, grouping the packet with the constituent flow.

IPC Classes  ?

• H04L 47/2441 - Traffic characterised by specific attributes, e.g. priority or QoS relying on flow classification, e.g. using integrated services [IntServ]
• H04L 41/147 - Network analysis or design for predicting network behaviour

Abstract

S. cerevisiae, suggesting a strategy to improve the yield of ethanol and other yeast fermentation products by manipulating native biological control systems.

IPC Classes  ?

• C12P 7/22 - Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
• C12N 1/18 - Baker's yeast; Brewer's yeast
• C12P 7/06 - Ethanol, i.e. non-beverage
• C12R 1/865 - Saccharomyces cerevisiae

Abstract

A biocompatible implant, as well as method of fabricating the implant and repairing an annular defect in annulus fibrosus (AF) of an intervertebral disc (IVD) disposed in a functional spinal unit (FSU), includes an insert that provides faces that can interface with the defect to repair or treat the AF. The implant can deliver biological and mechanical factors to enhance healing in an annular defect and prevent recurrence of herniation symptoms. The implant can be fabricated using a hybrid of first fibrous scaffold structure including at least a first layer and a second layer of first fibers fabricated via three-dimensional fiber deposition (3FD) and second fibrous scaffold structure including a third layer and a fourth layer of second fibers formed via melt electrowriting (MEW). Suitable attachment methods, including bio-adhesives can be used to bond the implant to the IVD and/or FSU.

IPC Classes  ?

• A61F 2/44 - Joints for the spine, e.g. vertebrae, spinal discs
• A61F 2/30 - Joints

Abstract

A device for emitting photons into a fluid is disclosed. The device includes a fluid channel configured to transfer the fluid from an inlet to an outlet thereof and the fluid channel having a helical pathway wound about a longitudinal axis. The device also includes at least one inner light source adjacent the fluid channel, the at least one inner light source positioned between the fluid channel and the longitudinal axis and at least one outer light source adjacent the fluid channel, the fluid channel positioned between the outer light source and the longitudinal axis.

IPC Classes  ?

• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
• A61L 2/10 - Ultraviolet radiation

Abstract

Provided herein are methods for inactivating a microbe, the methods comprising contacting the microbe with UV light in the presence of riboflavin. In some embodiments, the microbe is a Mycobacterium tuberculosis. Vaccine compositions comprising inactivated microbes, and methods of use thereof, are also provided.

IPC Classes  ?

• A61K 39/04 - Mycobacterium, e.g. Mycobacterium tuberculosis
• A61K 41/17 - Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
• A61P 31/06 - Antibacterial agents for tuberculosis
• A61K 35/74 - Bacteria

Abstract

aaaa-disubstitution in PHAs enhances the thermal stability so substantially that the PHAs become melt-processable. Synergistically, this structural modification also endows the PHAs with the mechanical toughness, intrinsic crystallinity, and closed-loop chemical recyclability.

IPC Classes  ?

• C08G 63/08 - Lactones or lactides
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• C08G 63/02 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds
• C08G 63/06 - Polyesters derived from hydroxy carboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxy carboxylic acids
• C08G 63/668 - Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
• C08G 69/14 - Lactams

Abstract

Embodiments of the present disclosure relate to a denticle array. The denticle array includes a substrate and a plurality of denticles coupled to the substrate. Each denticle of the plurality of denticles includes an upper portion and a lower portion. The upper portion includes an upper body. The lower portion includes a lower body. The upper body includes a first prong extending from a front end of the denticle to a rear end of the denticle, a second prong extending from the front end of the denticle to a rear end of the denticle, and a third prong extending from the front end of the denticle to a rear end of the denticle. A first ridge separates the first prong and second prong. A second ridge separates the first prong from the third prong. The first prong has a length greater than the second prong and the third prong.

IPC Classes  ?

• D01F 6/64 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters from polycarbonates
• D01F 6/18 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polymers of unsaturated nitriles, e.g. polyacrylonitrile, polyvinylidene cyanide
• D01F 6/70 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyurethanes
• D01F 11/12 - Chemical after-treatment of man-made filaments or the like during manufacture of carbon with inorganic substances

Abstract

Provided herein are methods for inactivating a viral particle, the methods comprising contacting the viral particle with UV light in the presence of riboflavin. In some embodiments, the viral particle is a SARS-CoV-2 particle. Vaccine compositions comprising inactivated viral particles (e.g., inactivated SARS-CoV-2 particles) are also provided. In some embodiments, the vaccine compositions comprise an adjuvant capable of promoting a Th1-type immune response.

IPC Classes  ?

• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61P 31/14 - Antivirals for RNA viruses
• A61K 39/215 - Coronaviridae, e.g. avian infectious bronchitis virus

Abstract

in situin situ generated dynamic thermosets exhibit intrinsic reprocessability as well as enhanced tensile strength and creep resistance, relative to virgin plastics. This approach avoids the need for de/reconstruction and thus provides the maximum recovery of the endowed energy and materials value of the individual plastics.

IPC Classes  ?

• C07D 403/02 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings
• C07D 403/10 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
• C08K 5/3442 - Heterocyclic compounds having nitrogen in the ring having two nitrogen atoms in the ring
• C07D 229/02 - Heterocyclic compounds containing rings of less than five members having two nitrogen atoms as the only ring hetero atoms containing three-membered rings

Abstract

The present disclosure provides thermoplastic elastomer (TPE) composites, TPE hydrogel composites, TPE gel polymer electrolyte (GPE) composites, methods of preparing the TPE composites, methods of preparing the TPE hydrogel composites, methods of preparing the TPE GPE composites. The thermoplastic elastomer (TPE) composite comprises a first styrenic thermoplastic elastomer and a second styrenic thermoplastic elastomer, wherein the first and second styrenic thermoplastic elastomers each independently comprise at least one non-hydrogenated or hydrogenated styrene block.

IPC Classes  ?

• H01M 10/0565 - Polymeric materials, e.g. gel-type or solid-type
• H01M 10/056 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes
• H01M 10/0564 - Accumulators with non-aqueous electrolyte characterised by the materials used as electrolytes, e.g. mixed inorganic/organic electrolytes the electrolyte being constituted of organic materials only

Abstract

The present disclosure provides compositions and methods for sensing a target substance of interest in the environment and inducing gene expression in response thereto, useful for detection of biological and chemical agents and environmental pollutants.

IPC Classes  ?

• C07K 14/705 - Receptors; Cell surface antigens; Cell surface determinants
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 15/62 - DNA sequences coding for fusion proteins

Abstract

A microfluidic device includes a device body defining a microfluidic pathway including a first channel, a second channel downstream of the first channel, and a junction including a transition between the first channel and the second channel. The transition is configured to inhibit fluid entering the transition from the first channel from forming a meniscus across the second channel, thereby inhibiting capillary-driven flow into the second channel. The microfluidic device further includes a valve that, when activated while capillary-driven flow of the fluid is inhibited at the transition, induces capillary-driven flow through the second channel by facilitating formation of the meniscus.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

Abstract

Biodegradable polymers with advantageous physical and chemical properties are described, as well as methods for making such polymers. In one embodiment, a new chemical synthesis route to technologically important biodegradable poly(3-hydroxybutyrate) (P3HB) with high isotacticity and molecular weight required for a practical use is described. The new route can utilize racemic eight-membered cyclic diolide (rac-DL), meso-DL, or a rac-DL and meso-DL mixture, derived from bio-sourced dimethyl succinate, and enantiomeric (R,R)-DL and (S,S)-DL, optically resolved by metal-based catalysts. With a stereoselective racemic molecular catalyst, the ROP of rac-DL under ambient conditions produces rapidly P3HB with essentially perfect isotacticity ([mm]>99%), high crystallinity and melting temperature (Tm=171° C.), as well as high molecular weight and low dispersity (Mn=1.54×105 g/mol, Ð=1.01).

IPC Classes  ?

• C08G 63/08 - Lactones or lactides
• C08G 63/82 - Preparation processes characterised by the catalyst used
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
• B01J 31/22 - Organic complexes

Abstract

A system for generating steam for industrial heat. The system may include a plurality of heat pump cycles in thermal communication with each other and in thermal communication with a steam generation cycle. The plurality of heat pump cycles may include first and second heat pump cycles. The first heat pump circulates a first a working fluid and includes a first heat exchanger. The second heat pump cycle circulates a second working fluid and includes a second heat exchanger. The first heat exchanger transfers heat from the first to the second working fluid. The second heat exchanger transfers heat to a third working fluid in the steam generation cycle.

IPC Classes  ?

• F22B 1/16 - Methods of steam generation characterised by form of heating method by exploitation of the heat content of hot heat carriers the heat carrier being hot liquid or hot vapour, e.g. waste liquid, waste vapour
• F01K 9/00 - Steam engine plants characterised by condensers arranged or modified to co-operate with the engines
• F01K 19/04 - Regenerating by compression in combination with cooling or heating

Abstract

An assay device includes a colorimetric testing assembly including a detection area, a fluid inlet, and a microfluidic network including a first path extending to the detection area and a second path extending to the detection area. When a fluid (e.g., a buffer fluid or a combined buffer and sample solution) is provided to the fluid inlet, a first portion of the fluid rehydrates a first dried reagent (e.g., a dried enzyme label) disposed along the first path to produce a first rehydrated reagent and a second portion of the fluid rehydrates a second dried reagent (e.g., a dried substrate) to produce a second rehydrated reagent. The first rehydrated reagent and the second rehydrated reagent are then sequentially delivered to the detection area by capillary-driven flow to perform the assay.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
• G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

Abstract

An assay device includes an electrochemical testing assembly having a test channel including a capture reagent selected to capture a target analyte and an electrode having a surface in communication with the test channel. The assay device further includes a microfluidic network in communication with the test channel, a buffer fluid inlet in communication with the microfluidic network, and a detection reagent disposed within the microfluidic network. When a buffer fluid is provided to the buffer fluid inlet, the buffer fluid transports the detection reagent to the test channel by capillary-driven flow, and wherein the electrode is configured to measure an electrical response indicating capture of the target analyte by the capture reagent after transportation of the detection reagent to the test channel.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

Abstract

An exemplary system and method are disclosed for a digital microfluidic chip cartridge and system configured for electro-wetting on dielectric (EWOD) microfluidic operations and experimental analysis. The exemplary portable lab-on-a-chip devices and systems can be configured to execute complex assays such as DNA isolation employing integrated sensor and electronics can analyze results. The EWOD or digital microfluidic cartridge can be configured with customizable assays having preloaded reagents targeted specifically for a given assay that can be used in an analysis in the field (i.e., point of care, i.e., not in a central laboratory) using a disposable or recyclable assay cartridge system. The cartridge and portable instrument can operate on specific instructions based on the algorithm intended for the assay.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

Abstract

Aspects of the present disclosure include a jet impingement cooling system configured to cool high heat flux devices via a cooling fluid. The jet impingement cooling system may include a heatsink and a first supply surface. The heatsink is coupled to the high heat flux device or capable of being coupled to the high heat flux device. The heatsink includes a first impingement surface having exit orifices and impingement regions. The exit orifices are spaced-apart from each other and defined in the first impingement surface. The impingement regions are located between adjacent exit orifices. The first supply surface is spaced-apart from the first impingement surface and includes injection ports spaced-apart from each other and defined in the supply surface. The injection ports are oriented such that impingement jets therefrom are directed to impinge against the impingement regions.

IPC Classes  ?

• H01L 23/473 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing liquids
• F28F 3/12 - Elements constructed in the shape of a hollow panel, e.g. with channels
• H01L 23/367 - Cooling facilitated by shape of device
• H01L 23/467 - Arrangements for cooling, heating, ventilating or temperature compensation involving the transfer of heat by flowing fluids by flowing gases, e.g. air
• F28D 15/02 - Heat-exchange apparatus with the intermediate heat-transfer medium in closed tubes passing into or through the conduit walls in which the medium condenses and evaporates, e.g. heat-pipes
• F28F 13/06 - Arrangements for modifying heat transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media
• F28F 27/02 - Control arrangements or safety devices specially adapted for heat-exchange or heat-transfer apparatus for controlling the distribution of heat-exchange media between different channels
• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating

Abstract

The disclosure relates to 2'‐deoxy‐2'‐fluoroarabinonucleic acid (FANA) antisense oligonucleotides that can be utilized to control weeds, invasive plants, or other undesired plants.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• A01H 3/04 - Processes for modifying phenotypes by treatment with chemicals
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A01N 61/00 - Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
• A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermen
• C12N 15/09 - Recombinant DNA-technology

Abstract

A tuber seed cutter sterilization device is disclosed. The tuber seed cutter is configured to receive a flammable gas and sterilize a tuber seed cutter having a rotational blade and a tuber conveyer, the rotational blade is configured to rotate about a longitudinal axis of a rotational shaft. The tuber seed cutter includes a fluid channel configured to receive the flammable gas at an inlet port and direct the flammable gas to a pair of outlet ports, each outlet port of the pair of outlet ports positioned at opposite axial sides of the rotational blade. The flammable gas is configured to be ignited into a flame at each outlet port of the pair of outlet ports and each flame of the pair of outlet ports is configured to heat opposite outer surfaces of the rotational blade.

IPC Classes  ?

• A01C 1/00 - Apparatus, or methods of use thereof, for testing or treating seed, roots, or the like, prior to sowing or planting
• A01C 1/08 - Immunising seed
• A23L 19/10 - Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
• A23L 19/12 - Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops of potatoes
• A23L 3/00 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
• A61L 2/04 - Heat

Abstract

Embodiments of the present disclosure relate to methods of a method of making agricultural waste ash supplementary cementitious materials (AWASCMs), the method includes pretreating agricultural waste with acid, burning the acid pretreated agricultural waste to form agricultural waste ash (AWA), heat treating the AWA, grinding the AWA into an AWA supplemental cementitious material (AWASCM), and mixing the AWASCM with cement, water, and supplementary cementitious materials (SCMs) to create a cement paste. Embodiments of the present disclosure relate to a composition including sand, coarse aggregate, and cementitious materials. The cementitious materials includes cement, a SCM, and an AWASCM. The AWASCM includes an AWA and AWF.

IPC Classes  ?

• C04B 28/02 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
• C04B 18/24 - Vegetable refuse, e.g. rice husks, maize-ear refuse; Cellulosic materials, e.g. paper
• C04B 7/28 - Cements from oil shales, residues or waste other than slag from combustion residues

Abstract

An upflow leach bed reactor configured to contain a substrate is provided. The reactor includes a container comprising a floor and a sidewall and configured to contain the substrate. The reactor further includes a fluid injection system including a plurality of fluid inlet ports arranged in an array across the floor. The fluid inlet ports can be moved between a first position below the substrate and a second position at least partially within the substrate. The reactor can also include a vertical drain extending from the top to the floor, between the substrate and the sidewall, and configured to permit downward liquid flow and inhibit upward liquid flow therethrough. The reactor can further include an inflatable bladder positioned adjacent the top of the container and configured to press downward against a top surface of the substrate.

IPC Classes  ?

• C02F 3/28 - Anaerobic digestion processes
• C02F 11/04 - Anaerobic treatment; Production of methane by such processes
• C02F 3/30 - Aerobic and anaerobic processes

Abstract

The present disclosure provides materials and methods related to engineered bacteria for use in vaccines. In particular, the present disclosure provides novel compositions and methods for generating vaccine compositions comprising bacteria (e.g., Lactobacillus) engineered to express immunogenic polypeptides and immunogenicity-enhancing adjuvant polypeptides to treat and/or prevent infection from a pathogenic organism (e.g., coronavirus).

IPC Classes  ?

• A61K 35/744 - Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
• C12N 1/20 - Bacteria; Culture media therefor
• C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
• C07K 14/165 - Coronaviridae, e.g. avian infectious bronchitis virus
• A61P 31/14 - Antivirals for RNA viruses
• C07K 14/14 - Reoviridae, e.g. rotavirus, bluetongue virus, Colorado tick fever virus

Abstract

A soil fractionation system can include a plurality of sample racks propelled by a drive system. Each sample rack can include a sample tube for holding a soil sample and a filter cup for receiving an extracted fraction of the soil sample. An extractor module of the fractionation system can include an extractor assembly and a filter assembly. A control system can control the relative positioning of the plurality of sample racks via the drive system, the relative movement between the extractor assembly and the sample tube, and the relative movement between the filter assembly and the filter cup.

IPC Classes  ?

• G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Abstract

Disclosed herein are systems and methods to perform hybridized transmission switching of an electric power system to avoid exceeding line ratings and minimize load shedding.

IPC Classes  ?

• H02J 3/00 - Circuit arrangements for ac mains or ac distribution networks
• H02J 3/14 - Circuit arrangements for ac mains or ac distribution networks for adjusting voltage in ac networks by changing a characteristic of the network load by switching loads on to, or off from, network, e.g. progressively balanced loading

Abstract

The present disclosure provides potentiometric ion selective electrodes, methods for preparing the potentiometric ion selective electrode, a microfluidic electrode array comprising the potentiometric ion selective electrodes, and methods of using the microfluidic electrode array to measure inorganic cations and inorganic anions in a solution.

IPC Classes  ?

• G01N 27/333 - Ion-selective electrodes or membranes
• G01N 27/416 - Systems

Abstract

A substrate having an antibacterial surface includes a chitosan matrix and water-stable metal-organic frameworks dispersed throughout the chitosan matrix. The water-stable metal-organic frameworks are present in an amount of 5% wt/wt to 20% wt/wt based on total solids of the substrate.

IPC Classes  ?

• A01N 55/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
• A01N 25/10 - Macromolecular compounds
• A61L 2/18 - Liquid substances
• A61L 2/23 - Solid substances, e.g. granules, powders, blocks, tablets
• C08B 37/08 - Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
• C08K 5/56 - Organo-metallic compounds, i.e. organic compounds containing a metal-to-carbon bond

Abstract

The present disclosure relates to a plant or plant part comprising increased expression of a polynucleotide encoding a CYP72A219 polypeptide that confers to the plant or plant part tolerance to HPPD inhibitor herbicides, such as tembotrione or mesotrione. The disclosure further provides kits for identifying herbicide resistant plants and methods for determining whether a plant is herbicide resistant.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C07K 14/415 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

In some embodiments, an apparatus includes a volatile memory, a non-volatile memory, a first processor coupled to the non-volatile memory and configured to receive a data set associated with an object and user information associated with a spatial position of a user in a multi-user virtual (IMVR) environment, and a second processor coupled to the volatile memory, the second processor configured to render an instance of the portion of the object in the IMVR environment from a perspective of the user based on the spatial position of the user. The first processor is configured to generate a look-up table (LUT) based on a set of inputs received from a user. The second processor is configured to render, based on the LUT and information related to a manipulation by a user, an updated instance of the portion of the object that manifests an effect of the manipulation in the IMVR environment.

IPC Classes  ?

• G06T 15/08 - Volume rendering
• G06T 1/60 - Memory management
• G06T 7/00 - Image analysis
• G06T 19/20 - Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
• G06T 19/00 - Manipulating 3D models or images for computer graphics
• G02B 27/01 - Head-up displays

Abstract

Various implementations include a biomass dehydration system including a wet biomass chamber containing wet biomass, a belt or chain defining one or more cavities, two or more pulleys including a drive pulley that the belt or chain extend around and that are configured such that the cavities are disposable within the wet biomass chamber as the belt or chain moves along the pulleys to cause wet biomass to enter the cavities, and a drying chamber for dehydrating wet biomass disposed in the cavities into solid pellets. The drive pulley engages the belt or chain and causes the belt or chain to move around the pulleys. At least a portion of the belt or chain extends from the wet biomass chamber through the drying chamber. One of the pulleys includes one or more ejection protrusions for engaging the cavities and ejecting solid pellets from the cavities.

IPC Classes  ?

• F26B 3/04 - Drying solid materials or objects by processes involving the application of heat by convection, i.e. heat being conveyed from a heat source to the materials or objects to be dried by a gas or vapour, e.g. air the gas or vapour circulating over, or surrounding, the materials or objects to be dried
• F26B 17/02 - Machines or apparatus for drying materials in loose, plastic, or fluidised form, e.g. granules, staple fibres, with progressive movement with movement performed by belts propelling the materials over stationary surfaces
• F26B 25/00 - DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM - Details of general application not covered by group or
• F26B 25/04 - Agitating, stirring, or scraping devices
• F26B 23/02 - Heating arrangements using combustion heating

Abstract

Embodiments of the present invention generally relate to novel immunostimulatory compositions of use to stimulate non-specific immune responses in a subject. In certain embodiments, immunostimulatory compositions disclosed herein can be directed to preventing or treating an infection, cancer or other immunocompromising health condition in the subject. In some embodiments, the immunostimulatory compositions disclosed herein enhance non-specific immune responses systemically or locally in the subject to treat or reduce the risk of onset of a health condition. In some embodiments, immunostimulatory compositions disclosed can be used to induce a non-specific immune response within mucosal surfaces such as the nasopharynx, upper respiratory tract, eye, GI tract, and reproductive tract to induce a non-specific immune response in order to reduce onset of or treat an infection or other health condition.

IPC Classes  ?

• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61K 9/127 - Liposomes
• A61K 47/38 - Cellulose; Derivatives thereof
• A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
• A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 31/12 - Antivirals
• A61P 37/04 - Immunostimulants

Abstract

The present disclosure provides recombinant polynucleotide comprising a heterologous regulatory element operably linked to a first nucleic acid sequence encoding a cyanobacterial bicarbonate transporter protein. The disclosure also provides expression vectors comprising the recombinant polynucleotides as well as eukaryotic algae and methods of utilizing the eukaryotic algae for improved carbon removal and biomass production.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C07K 14/195 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria

Abstract

The disclosure relates to compositions and methods for reducing free asparagine concentration in the grain of wheat plants. The compositions comprise wheat plants, plant parts, plant cells, and seeds comprising a loss-of-function mutation in at least one endogenous ASPARAGINE SYNTHETASE 2 (ASN2) gene. The grain of wheat plants has reduced acrylamide-forming potential. Low acrylamide products produced from the grain are also provided.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• A01H 6/46 - Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
• C12N 9/22 - Ribonucleases
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae

Abstract

A power plant system is disclosed. The power plant system includes a combustor, a turbine configured to generate electricity, a carbon capture system configured to remove at least a portion of carbon-based gasses from the flue gas downstream from the combustor, and a thermal storage system including a hot storage unit configured to store heat generated at least by resistively-heated gas at a hot temperature, the hot temperature greater than ambient temperature. The power plant is configured to operate in at least a first mode for storing thermal energy in the thermal storage system and a second mode for releasing the stored thermal energy from the thermal storage system and during the second mode, heat stored in the hot storage unit is transferred to the carbon capture system.

IPC Classes  ?

• F01K 3/12 - Plants characterised by the use of steam or heat accumulators, or intermediate steam heaters, therein having two or more accumulators
• F01K 17/02 - Use of steam or condensate extracted or exhausted from steam engine plant for heating purposes, e.g. industrial, domestic
• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F02C 6/04 - Gas-turbine plants providing heated or pressurised working fluid for other apparatus, e.g. without mechanical power output
• F02C 6/14 - Gas-turbine plants having means for storing energy, e.g. for meeting peak loads
• F02C 6/18 - Plural gas-turbine plants; Combinations of gas-turbine plants with other apparatus; Adaptations of gas-turbine plants for special use using the waste heat of gas-turbine plants outside the plants themselves, e.g. gas-turbine power heat plants

Abstract

A bio-barrier for reducing combustible gas emissions from the ground into the atmosphere is disclosed. The bio-barrier includes a geocomposite layer extending laterally beneath a top surface of the ground and a first geotextile layer extending laterally beneath the top surface of the ground and positioned above the geocomposite layer. The geocomposite layer and the geotextile layer configured to laterally disperse the combustible gas through at least the geotextile layer. In addition, at least one sensor may be positioned beneath the top surface of the ground and in or above the geocomposite layer, the at least one sensor measuring a parameter indicative of the concentration or oxidation of the combustible gas beneath the top surface of the ground.

IPC Classes  ?

• B01D 53/85 - Biological processes with gas-solid contact
• B01D 53/72 - Organic compounds not provided for in groups , e.g. hydrocarbons

Abstract

Inflammatory bowel disease (IBD) in humans and dogs and other companion animals is characterized by infiltration of lymphocytes and macrophages into the mucosa and submucosa and clinical signs of gastrointestinal (Gl) dysfunction (diarrhea, malabsorption, weight loss). Alteration of the gut environment and development of dysbiosis may allow the overgrowth of pathogenic bacteria and induction of intestinal injury and inflammation in IBD. What is needed are novel methods that allow for rapid diagnosis of IBD (and follow-up monitoring) and treatment of the disease. The present disclosure relates to methods for diagnosing and treating inflammatory bowel disease (IBD) or gastrointestinal lymphoma.

IPC Classes  ?

• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
• C12Q 1/6813 - Hybridisation assays
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Abstract

Electrochemical sensing devices and methods of using thereof employs a set of one or more sensor-integrated sampling wells or containers that operates with a pressure differential micro-valve to move controlled volume of sampled fluid within a controlled cell-growing environment. The differential micro-valve can be integrated into an instrumented well having one or more sensors to provide a high-throughput smart well plate platform for use in automation operation in diagnostics and drug discovery.

IPC Classes  ?

• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• G01N 27/416 - Systems
• C12M 1/26 - Inoculator or sampler
• C12M 1/00 - Apparatus for enzymology or microbiology

Abstract

A method may include receiving video data that includes frames representative of infrared radiation within a scene. Each of the frames may include pixels The method may also include identifying pixels within the frames that correspond to a gas plume released by a gas source within the scene based on the infrared radiation. In addition, the method may include determining a size of the gas plume within each frame based on the identified pixels.

IPC Classes  ?

• G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis

Abstract

A method may include receiving video data that includes frames representative of infrared radiation within a scene. Each of the frames may include pixels The method may also include identifying pixels within the frames that correspond to a gas plume released by a gas source within the scene based on the infrared radiation. In addition, the method may include determining a size of the gas plume within each frame based on the identified pixels.

IPC Classes  ?

• G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
• G01J 5/00 - Radiation pyrometry, e.g. infrared or optical thermometry

Abstract

A system may include a computer-readable storage media configured to store instructions. The system may also include one or more processors communicatively coupled to the one or more computer-readable storage media. The one or more processors may be configured to, in response to execution of the instructions, cause the system to perform operations. The operations may include measuring a pressure of a volume while a user wears a mask and breathes. The volume may be defined by an interior surface of the mask and a face of the user. The operations may also include determining a differential pressure due to the mask. The differential pressure may be equal to a difference between the pressure of the volume and an ambient pressure of an environment proximate an exterior surface of the mask. In addition, the operations may include determining a mask leakage rate of the mask based on the differential pressure.

IPC Classes  ?

• G01M 3/26 - Investigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
• A62B 27/00 - Methods or devices for testing respiratory or breathing apparatus

Abstract

Phenothiazine compounds of Formula (I) are described herein. These compounds are useful as highly reducing organic photoredox catalysts. Suitable substrates for use with the compounds of Formula (I) include acrylates, styrene, acrylamides, acrylonitrile, vinyl chloride, methylacrylonitrile, vinyl acetate, and acrylic acid.

IPC Classes  ?

• C07D 279/30 - [b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with acyl radicals attached to the ring nitrogen atom
• C07D 279/24 - [b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom

Abstract

An ultra-efficient turbo-compression cooling system links an organic Rankine power cycle and a vapor compression cooling cycle using a turbine and compressor that shares a single shaft and further linked to an evaporative condenser. The power cycle implements a waste heat exchanger configured to evaporate a working fluid and a turbine configured to receive the evaporated working fluid. The turbine has a plurality of vanes disposed around a central shaft and configured to rotate as the working fluid expands to a lower pressure within the turbine. An evaporative condenser then condenses the working fluid to a saturated liquid and a mechanical pump pumps the saturated liquid to reenter the waste heat waste heat exchanger. The cooling cycle implements a compressor configured to increase the pressure of the working fluid, with the evaporative condenser (shared with the power cycle) configured to condense the working fluid to a saturated liquid upon exiting the compressor, an expansion valve wherein the working fluid expands to a lower pressure, and an evaporator rejecting heat from a circulating fluid to the working fluid, thereby cooling the circulating fluid.

IPC Classes  ?

• F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
• F01K 11/02 - Steam engine plants characterised by the engines being structurally combined with boilers or condensers the engines being turbines
• F01K 25/10 - Plants or engines characterised by use of special working fluids, not otherwise provided for; Plants operating in closed cycles and not otherwise provided for using special vapours the vapours being cold, e.g. ammonia, carbon dioxide, ether
• F01D 17/14 - Final actuators arranged in stator parts varying effective cross-sectional area of nozzles or guide conduits
• F25B 27/02 - Machines, plants or systems, using particular sources of energy using waste heat, e.g. from internal-combustion engines
• F25B 9/00 - Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point
• F25B 1/10 - Compression machines, plants or systems with non-reversible cycle with multi-stage compression

Abstract

The invention discloses a method and a system to detect a target nucleic acid sequence in a sample using padlock probe-based rolling circle amplification and nuclease protection. Padlock probe-based rolling circle amplification and nuclease protection may be used in combination with other detection assays to detect target nucleic acid sequences in a sample.

IPC Classes  ?

• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

Abstract

∞∞∞∞ loopshaping and optimizes based on one or more second performance metrics that may include one or more of the first performance metrics.

IPC Classes  ?

• G05B 13/02 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
• G06F 1/26 - Power supply means, e.g. regulation thereof

Goods & Services

DOWNLOADABLE COMPUTER SOFTWARE FOR SIMULATING PLANT GROWTH, NUTRIENT UPTAKE, NUTRIENT MINERALIZATION, SOIL WATER AND TEMPERATURE DYNAMICS FOR THE PURPOSE OF ESTIMATING TRACE GAS EMISSIONS AND SOIL ORGANIC CARBON STOCKS FOR DIFFERENT ECOSYSTEMS, SOILS AND CLIMATES

Abstract

The disclosure relates to benzo[ghi]perylene imide photoredox catalysts (PC) and methods for the Birch reductions of aromatic substrates, such as benzene, benzeneoid, and heteroaromatic compounds, using light as the driving force. Certain aspects of the disclosure encompass methods for reduction of aromatic substrates. The method comprises contacting an aromatic substrate with a sacrificial electron donor in the presence of a photoredox catalyst in a solvent, thereby forming a reaction mixture; exposing the reaction mixture to visible or UV light under reaction condition sufficient to reduce the aromatic substrate compound.

IPC Classes  ?

• B01J 31/02 - Catalysts comprising hydrides, coordination complexes or organic compounds containing organic compounds or metal hydrides
• B01J 31/00 - Catalysts comprising hydrides, coordination complexes or organic compounds
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• C07D 209/62 - Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) fluthiacet-methyl in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/90 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) epyrifenacil (Acetic acid, 2-[[3-[2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl]-4-fluorophenoxy]-2-pyridinyl]oxy]-, ethyl ester) in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 43/54 - 1,3-Diazines; Hydrogenated 1,3-diazines
• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) carfentrazone-ethyl in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 43/653 - 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01P 13/00 - Herbicides; Algicides

Abstract

e.g.,Mycobacterium bovis e.g.,e.g., coronavirus).

IPC Classes  ?

• A61K 39/215 - Coronaviridae, e.g. avian infectious bronchitis virus
• A61K 39/04 - Mycobacterium, e.g. Mycobacterium tuberculosis
• A61K 39/12 - Viral antigens
• A61K 35/66 - Microorganisms or materials therefrom
• A61K 35/74 - Bacteria

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) oxadiazon in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 43/82 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms five-membered rings with three hetero atoms
• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01P 13/00 - Herbicides; Algicides

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) tiafenacil in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. he present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/54 - 1,3-Diazines; Hydrogenated 1,3-diazines

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) a PPO-inhibitor selected from Acifluorfen, Fomesafen or Lactofen in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01P 13/00 - Herbicides; Algicides
• A01N 61/00 - Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action

Abstract

Implementations described and claimed herein provide systems and methods for managing animal patient during a veterinary procedure. In one implementation, a base has an interior surface, an exterior surface, and an opening. An electrode is disposed in the opening. The electrode is configured to communicate with medical device(s) for monitoring vital(s) of the patient during the procedure. A thermal insulator extends from the base. The thermal insulator forms a housing. An internal cavity is defined within the housing. The foot of the patient is receivable into the internal cavity. The thermal insulator regulates the body temperature of the animal patient during the veterinary procedure by retaining heat within the internal cavity.

IPC Classes  ?

• A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
• A61B 5/01 - Measuring temperature of body parts
• A61D 99/00 - Subject matter not provided for in other groups of this subclass
• A61B 8/08 - Detecting organic movements or changes, e.g. tumours, cysts, swellings
• A61D 9/00 - Bandages, poultices, compresses specially adapted to veterinary purposes

Abstract

The present disclosure provides compositions and methods related to the detection of an analyte-of-interest. In particular, the present disclosure provides compositions and methods related to the detection and/or quantification of an analyte-of-interest using a signal detection component in combination with a signal amplification component. By combining these components in a modular format, cell-free synthetic gene circuits can be generated or improved to address a specific biological or biomedical diagnostic need.

IPC Classes  ?

• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
• G01N 21/64 - Fluorescence; Phosphorescence

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) sulfentrazone in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 43/653 - 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01P 13/00 - Herbicides; Algicides

Abstract

5 buffy coat cells by lipase-iron oxide bead-RT-QuIC performed at 42° C. (LIQ42) in 79% of CWD-biopsy positive WTD, which increased to 100% when LIQ was performed at 55° C. (LIQ55). RT-QuIC assessment of PMCA (PQ) round 5 product revealed hematogenous prions in 92% of the WTD.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Abstract

Various implementations include a combustor system including an inner wall, a fuel grate, an ash grinder, an igniter, and a fan. The inner wall defines a combustion chamber and has a longitudinal axis and first and second ends. The inner wall defines primary and secondary air inlets. The primary air inlets are defined closer than the secondary air inlets to the first end. The fuel grate is disposed within the combustion chamber between the primary and secondary air inlets and is configured to support fuel disposed within the combustion chamber. The ash grinder is disposed between the fuel grate and the secondary air inlets and is rotatable about the longitudinal axis relative to the fuel grate. The igniter provides energy to the combustion chamber. The fan is configured to cause air to flow from the primary and secondary air inlets through the second end of the combustion chamber.

IPC Classes  ?

• F23G 5/00 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels
• F23H 1/02 - Grates with solid bars having provision for air supply or air preheating, e.g. air-supply or blast fittings which form part of the grate structure or serve as supports
• F23H 15/00 - Cleaning arrangements for grates ; Moving fuel along grates
• F23Q 7/04 - Incandescent ignition; Ignition using electrically-produced heat, e.g. lighters for cigarettes; Electrically-heated glowing plugs for igniting solid fuel with fans for transfer of heat to fuel
• C02F 11/06 - Treatment of sludge; Devices therefor by oxidation

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) flumioxazin in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/84 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
• A01P 13/02 - Herbicides; Algicides selective

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) pyraflufen-ethyl in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/56 - 1,2-Diazoles; Hydrogenated 1,2-diazoles
• A01P 13/02 - Herbicides; Algicides selective

Abstract

An impingement cooling device including a distributor plate, a manifold, and a heat spreader. The distributor plate includes a first side, a second side opposite the first side, a plurality of injection ports extending through the distributor plate from the first side to the second side, and a plurality of extraction ports extending through the distributor plate from the first side to the second side. The manifold is coupled to the distributor plate and includes a partition wall separating the plurality of injection ports and the plurality of extraction ports on the first side. The heat spreader at least partially covers an object to be cooled and includes a top surface configured to oppose the second side of the distributor plate. The heat spreader further includes a surface feature on the top surface configured to increase heat transfer therefrom.

IPC Classes  ?

• H05K 7/20 - Modifications to facilitate cooling, ventilating, or heating

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) trifludimoxazin in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 25/04 - Dispersions or gels
• A01N 25/28 - Microcapsules

Abstract

A recombinant myxoma virus that encodes the orfC gene of walleye dermal sarcoma virus (WDSV). The orfC gene of walleye dermal sarcoma virus (WDSV) plays a role in induction of seasonal regression of tumors caused by WDSV. This gene was isolated from WDSV and recombined into myxoma virus (MYXV orfC) for use as an oncolytic therapy. The recombinant myxoma virus can be used in oncolytic virus therapy to specifically target and lyse cancer cells without harming healthy cells in cancer patients.

IPC Classes  ?

• C12N 15/86 - Viral vectors
• A61K 35/768 - Oncolytic viruses not provided for in groups
• A61K 38/16 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
• A61P 35/00 - Antineoplastic agents
• C12N 7/00 - Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof

Abstract

A microbial efficiency-matrix stabilization (MEMS) 2.0 ecosystem model, with detailed pools and fluxes for the litter and soil components, represents carbon (C) and nitrogen (N) fluxes among atmosphere, plants, and soil, in multiple soil layers down to a user-defined depth. Inputs and recycling of N cause feedbacks to net primary productivity (NPP), which is allocated aboveground (ANPP) or belowground (BNPP) and at different depths, depending on vegetation and soil traits.

IPC Classes  ?

• G06F 30/20 - Design optimisation, verification or simulation

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) saflufenacil in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/50 - 1,3-Diazoles; Hydrogenated 1,3-diazoles

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) flumiclorac-pentyl in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01N 43/38 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
• A01P 13/00 - Herbicides; Algicides

Abstract

A monomer design strategy based on a bridged bicyclic thiolactone that produces stereo-disordered to perfectly stereo-ordered polythioesters is disclosed. The described polythioesters exhibit high crystallinity and full chemical recyclability. Such polymers possess intrinsic tacticity-independent crystallinity and chemical recyclability, tunable tacticities from stereo-disorder to perfect stereoregularity, as well as combined high-performance properties such as high thermal stability and crystallinity, and high mechanical strength, ductility and toughness.

IPC Classes  ?

• C08G 75/26 - Polythioesters
• C07D 333/78 - Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings

Abstract

Methods for detecting a mycobacterial infection in a patient are disclosed. These methods include the step of detecting lipoarabinomannan (LAM) and/or derivatives thereof in a biological sample from the patient. Methods for diagnosing disease, including nontuberculous mycobacterial infection (NTM), and kits for the described methods are also provided.

IPC Classes  ?

• G01N 33/569 - Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
• G01N 33/92 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol

Abstract

Non-sewered toilet system and method for separation and treatment of human waste are described. The system can include a frontend system with a solids separator (100), a buffer tank separation system (200), a liquid waste treatment system (300), and a solids waste treatment system (500). The solids separator can separate combined human waste including feces or urine into a separated solids portion and a separated liquid portion. The buffer tank separation system can deliver a solids portion of the input stream to the solids collection tank and deliver the liquids portion to the liquids collection tank. The liquid waste treatment system can receive liquid waste collected in the liquids collection tank and deliver a usable water. The solids waste treatment system can receive a slurry from the solids collection tank, heat the slurry to inactivate pathogens, and form feces cakes with a filter press. A combustor can reduce the feces cakes to ash.

IPC Classes  ?

• C02F 9/00 - Multistage treatment of water, waste water or sewage
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• C02F 1/74 - Treatment of water, waste water, or sewage by oxidation with air
• C02F 11/121 - Treatment of sludge; Devices therefor by de-watering, drying or thickening by mechanical de-watering
• C02F 11/123 - Treatment of sludge; Devices therefor by de-watering, drying or thickening by mechanical de-watering using belt or band filters
• C02F 11/128 - Treatment of sludge; Devices therefor by de-watering, drying or thickening by mechanical de-watering using batch processes
• C02F 11/16 - Treatment of sludge; Devices therefor by de-watering, drying or thickening using drying or composting beds
• C02F 11/18 - Treatment of sludge; Devices therefor by thermal conditioning
• C02F 11/06 - Treatment of sludge; Devices therefor by oxidation
• C02F 11/122 - Treatment of sludge; Devices therefor by de-watering, drying or thickening by mechanical de-watering using filter presses
• E03D 1/14 - Cisterns discharging variable quantities of water
• E03D 5/014 - Special constructions of flushing devices combined with movable closure elements in the bowl outlet with devices for separate removal of liquids and solids
• E03D 11/11 - Bowls combined with a reservoir, e.g. containing apparatus for disinfecting or for disintegrating
• B01D 33/04 - Filters with filtering elements which move during the filtering operation with filtering bands or the like supported on cylinders which are impervious for filtering
• B01D 29/35 - Self-supporting filtering elements arranged for outward flow filtration
• B01D 61/02 - Reverse osmosis; Hyperfiltration
• B01D 61/14 - Ultrafiltration; Microfiltration
• B01D 61/16 - Feed pretreatment
• B01D 61/58 - Multistep processes
• B01D 29/90 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups ;   Filtering elements therefor having feed or discharge devices for feeding
• E03F 1/00 - Methods, systems, or installations for draining-off sewage or storm water
• C02F 1/20 - Treatment of water, waste water, or sewage by degassing, i.e. liberation of dissolved gases

Abstract

Various systems and methods for two-chamber combustion system are described. The system includes a combustion section (102) comprising a containment wall (122), a first combustion chamber (110), and a second combustion chamber (112). The first combustion chamber is positioned beneath the second combustion chamber and configured to receive a first fuel. The second combustion chamber configured to receive a second fuel comprising feces. The system also including an exhaust duct (106), a reducer (118) connecting the combustion section to the exhaust duct, and an exhaust vent (108) connected to the exhaust duct at an end opposite the combustion section and at a top of the combustor.

IPC Classes  ?

• F23G 7/00 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of specific waste or low grade fuels, e.g. chemicals
• F23B 10/00 - Combustion apparatus characterised by the combination of two or more combustion chambers
• F23B 60/02 - Combustion apparatus in which the fuel burns essentially without moving with combustion air supplied through a grate

Abstract

The present invention relates generally to an assay for detecting and differentiating single or multiple analytes, if present, in a fluid sample, including devices and methods of use of the same.

IPC Classes  ?

• G01N 33/558 - Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
• G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
• G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

Abstract

A system for generating steam for industrial heat. The system may include a plurality of heat pump cycles in thermal communication with each other and in thermal communication with a steam generation cycle. The plurality of heat pump cycles may include first and second heat pump cycles. The first heat pump circulates a first a working fluid and includes a first heat exchanger. The second heat pump cycle circulates a second working fluid and includes a second heat exchanger. The first heat exchanger transfers heat from the first to the second working fluid. The second heat exchanger transfers heat to a third working fluid in the steam generation cycle.

IPC Classes  ?

• F25B 7/00 - Compression machines, plants or systems, with cascade operation, i.e. with two or more circuits, the heat from the condenser of one circuit being absorbed by the evaporator of the next circuit
• F22B 1/00 - Methods of steam generation characterised by form of heating method
• F25B 11/04 - Compression machines, plants or systems, using turbines, e.g. gas turbines as expanders centrifugal type
• F25B 25/02 - Compression-sorption machines, plants, or systems
• F25B 27/00 - Machines, plants or systems, using particular sources of energy
• F25B 30/02 - Heat pumps of the compression type
• F25B 31/02 - Compressor arrangements of motor-compressor units
• F25B 9/00 - Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point

Abstract

A system for generating steam for industrial heat. The system may include a plurality of heat pump cycles in thermal communication with each other and in thermal communication with a steam generation cycle. The plurality of heat pump cycles may include first and second heat pump cycles. The first heat pump circulates a first a working fluid and includes a first heat exchanger. The second heat pump cycle circulates a second working fluid and includes a second heat exchanger. The first heat exchanger transfers heat from the first to the second working fluid. The second heat exchanger transfers heat to a third working fluid in the steam generation cycle.

IPC Classes  ?

• F22B 1/00 - Methods of steam generation characterised by form of heating method
• F25B 7/00 - Compression machines, plants or systems, with cascade operation, i.e. with two or more circuits, the heat from the condenser of one circuit being absorbed by the evaporator of the next circuit
• F25B 9/00 - Compression machines, plants or systems, in which the refrigerant is air or other gas of low boiling point
• F25B 11/04 - Compression machines, plants or systems, using turbines, e.g. gas turbines as expanders centrifugal type
• F25B 25/02 - Compression-sorption machines, plants, or systems
• F25B 27/00 - Machines, plants or systems, using particular sources of energy
• F25B 30/02 - Heat pumps of the compression type
• F25B 31/02 - Compressor arrangements of motor-compressor units

Abstract

Described herein are systems, methods, and devices for detecting harmful algae blooms. An example system includes autonomous watercraft; and a computing device operably connected to the autonomous watercraft over a network, the computing device including a processor and a memory having computer-executable instructions stored thereon that cause the processor to: surveil a body of water for an algae growth; receive a local condition at the body of water; predict a spread of the algae growth in the body of water based on the local condition; determine a deployment strategy for the autonomous watercraft based on the spread of the algae growth; and transmit one or more control signals to the plurality of autonomous watercraft based on the deployment strategy, where the autonomous watercraft are configured to collect and analyze a plurality of water samples to determine whether the algae growth is a harmful algae bloom.

IPC Classes  ?

• G01N 33/18 - Water
• B64C 39/02 - Aircraft not otherwise provided for characterised by special use
• B63B 35/00 - Vessels or similar floating structures specially adapted for specific purposes and not otherwise provided for

Abstract

The present application relates to preparation methods and uses of vanadium complexes providing a consistent and stable preparation. More specifically, the present application relates to preparation of vanadium citrate salts, phosphate salts, or combinations thereof, characterization of the properties of such salts, and methods using the same.

IPC Classes  ?

• C07F 9/00 - Compounds containing elements of Groups 5 or 15 of the Periodic System

Abstract

The present disclosure provides compositions and methods related to the treatment of non-tuberculous mycobacterial infections in a subject. In particular, the present disclosure provides compositions comprising an anti-malarial agent and associated methods of treating and/or preventing a non-tuberculous mycobacterial infection in a subject using the composition.

IPC Classes  ?

• A61K 31/357 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 31/08 - Antibacterial agents for leprosy

Abstract

The present application relates to preparation methods and uses of vanadium complexes providing a consistent and stable preparation. More specifically, the present application relates to preparation of vanadium citrate salts, phosphate salts, or combinations thereof, characterization of the properties of such salts, and methods using the same.

IPC Classes  ?

• A61K 47/12 - Carboxylic acids; Salts or anhydrides thereof
• A61K 33/24 - Heavy metals; Compounds thereof
• A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
• A61P 35/00 - Antineoplastic agents
• A61P 37/02 - Immunomodulators
• B01J 31/36 - Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups of vanadium, niobium or tantalum
• H01M 8/18 - Regenerative fuel cells, e.g. redox flow batteries or secondary fuel cells

Abstract

3 phosphorus ligand-coupling, an underdeveloped manifold for C—C bond formation.

IPC Classes  ?

• C07F 9/50 - Organo-phosphines
• C07F 9/572 - Five-membered rings
• C07B 47/00 - Formation or introduction of functional groups not provided for in groups

Abstract

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) oxyfluorfen in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.

IPC Classes  ?

• A01N 33/22 - Nitro compounds containing oxygen or sulfur attached to the carbon skeleton containing the nitro group having at least one oxygen or sulfur atom and at least one nitro group directly attached to the same aromatic ring system
• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01P 13/00 - Herbicides; Algicides

Abstract

The present application relates to vanadium compounds. More specifically, the present application relates to pharmaceutical compositions comprising vanadium salts, use thereof and methods using the same. The present application also includes compositions comprising vanadium compounds and a therapeutic or prophylactic virus providing for increased virus infection, spread, titer, activity, cytotoxicity and/or immunotherapeutic activity.

IPC Classes  ?

• A61K 31/555 - Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
• A61K 33/24 - Heavy metals; Compounds thereof
• A61K 35/76 - Viruses; Subviral particles; Bacteriophages
• A61K 35/761 - Adenovirus
• A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
• A61P 35/00 - Antineoplastic agents
• A61P 37/04 - Immunostimulants
• C07F 9/00 - Compounds containing elements of Groups 5 or 15 of the Periodic System
• C07F 9/06 - Phosphorus compounds without P—C bonds

Abstract

Provided herein is a method for removing uremic toxins from blood is provided. The method includes exposing blood to iron-based metal-organic frameworks; and allowing the metal-organic frameworks to bind a least one uremic toxin in the blood.

IPC Classes  ?

• B01J 20/22 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
• G01N 15/08 - Investigating permeability, pore volume, or surface area of porous materials
• B01D 15/00 - Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor

Abstract

Embodiments of the present invention relate to compositions and methods for activating canine OX40 to treat a condition in dogs. In certain embodiments, the condition can be cancer or an immunosuppressed condition in dogs and OX40 activation treats, ameliorates or prevents onset or progression of the condition. In other embodiments, compositions disclosed herein generally relate to compositions including, but not limited to, activating antibodies having specific affinity for OX40 for inducing activity of canine OX40. In other embodiments, compositions disclosed herein can be used for treating certain cancers or an immunosuppressed condition to treat the cancer or alleviate immunosuppression in dogs. In certain embodiments, other immune activators can be administered in combination with OX40 activating antibodies such as Toll-Like Receptor (TLR) ligands alone or in combination with other non-specific immunostimulant agents.

IPC Classes  ?

• C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
• A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 35/00 - Antineoplastic agents

Abstract

Disclosed herein are methods of carbon sequestration using microorganisms, such as soil microorganisms, capable of synthesizing or consuming degradation-resistant L-carbohydrates. In particular, methods of identifying and using microorganisms capable of synthesizing L-carbohydrates are provided, wherein microorganisms that synthesize L-carbohydrates are contacted with a soil source to sequester carbon. Also provided are methods of identifying and incorporating biomolecules such as genes, peptides, and enzymes relevant for L-carbohydrate anabolism or catabolism into plants so the plants synthesize L-carbohydrates or do not consume L-carbohydrates, thereby sequestering carbon.

IPC Classes  ?

• C05G 3/80 - Soil conditioners
• C12P 19/02 - Monosaccharides
• C12N 15/00 - Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
• C12N 15/01 - Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
• C12N 15/09 - Recombinant DNA-technology
• C12N 15/52 - Genes encoding for enzymes or proenzymes

Abstract

The present disclosure relates to a laser diode system. The system may have at least one laser diode emitter having a substrate, at least one laser diode supported on the substrate, and a facet which a laser beam generated by the laser diode is emitted. A cooling subsystem is included which is disposed in contact with the substrate of the laser diode emitter. The cooling subsystem includes a plurality of cooling fins forming a plurality of elongated channels for circulating a cooling fluid therethrough to cool the laser diode emitter. The cooling fluid also flows over the facet of the laser diode emitter.

IPC Classes  ?

• H01S 5/40 - Arrangement of two or more semiconductor lasers, not provided for in groups
• H01S 5/024 - Arrangements for thermal management