Abrégé

Detailed herein are systems, methods, and devices configured for detecting symptoms of depression in a home dialysis patient. These systems, methods, and device may be embodied in a home dialysis system. The home dialysis system may be configured to carry out a home dialysis treatment on a patient. During the home dialysis treatment, the home dialysis system may be configured to detect one or more symptoms of depression and to generate a medical alert based on the detected one or more symptoms.

Classes IPC  ?

• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale
• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/28 - Dialyse péritonéale

Abrégé

A computing system for determining a systematic training strategy for the user is provided. The computing system includes a user device that uses one or more sensors to obtain partial pressure of oxygen (PO2) levels of a user over a period of time. The user device provides previous PO2 levels to a personalized erythropoiesis model generation computing platform. The computing platform obtains individualized user data for the user indicating or more previous hematocrit and/or hemoglobin measurements for the user. The computing platform determines an individualized erythropoiesis model for the user based on the one or more previous hematocrit and/or hemoglobin measurements and the previous PO2 information, and employs the individualized erythropoiesis model to determine predicted hematocrit and/or hemoglobin measurements. The computing platform performs one or more actions based on the one or more predicted hematocrit and/or hemoglobin measurements.

Classes IPC  ?

• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
• A63B 22/00 - Appareils d'exercice spécialement adaptés à l'entraînement du système cardio-vasculaire, pour exercer l'agilité ou la coordination des mouvements

Abrégé

A method for determining a next hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) dosage for a first patient using a patient HIF-PHI model is provided. The method includes obtaining population patient data indicating HIF-PHI dosages and hemoglobin measurements for the patients. Then, virtual patient avatars are generated based on the population patient data. Each of the virtual patient avatars indicates a set of personalized model parameters for a HIF-PHI model. A plurality of HIF-PHI models are determined for the virtual patient avatars. Using the HIF-PHI models, one or more HIF-PHI treatment schemes for administering the HIF-PHI dosages is determined. Subsequently, the HIF-PHI treatment schemes along with a hematocrit and/or hemoglobin concentration for a patient are used to determine a next HIF-PHI dosage for the patient, and the next HIF-PHI dosage is administered for the patient.

Classes IPC  ?

• G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
• G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients

Abrégé

A method of monitoring a medical treatment device includes detecting a sound of the medical treatment device with a detection device, determining whether the sound is an irregular sound, and deploying an intervention upon determining that the sound is the irregular sound.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/28 - Dialyse péritonéale
• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
• G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance

Abrégé

A system includes a sensor element arranged to detect a spectrum of noise or vibrations of a medical device to be supervised the, a supervising element, whereby the sensor element and the supervising element may communicate with each other and thereby allow for provisioning of data corresponding to the acoustic signals, whereby the system further comprises a localized or distributed detection engine, the detection engine analyzing the data corresponding to the acoustic signals such that typical failures of each of a plurality of individual components of the medical device are distinguished, whereby the system further comprises a notification engine, the notification engine providing indications on the maintenance state of the medical device and/or one or more of the plurality of individual components of the medical device. The disclosure also pertains to a computer‐implemented method for determining a maintenance state of a medical device.

Classes IPC  ?

• G05B 23/02 - Test ou contrôle électrique

Abrégé

Medical devices and peripheral devices can be configured to wirelessly communicate with each other and other devices through a connection between the devices. Peripheral devices may include weight scales, blood pressure monitors and/or other medical components that may be used in connection with measuring patient information related to a medical treatment by a medical device, such as a dialysis treatment performed by a dialysis machine. A medical function/data transfer device according to the system described herein may include multi-function capabilities to provide for a medical monitoring or treatment function as well as a data transfer function for transferring data between interconnected medical devices.

Classes IPC  ?

• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation
• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
• H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p.ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
• H04W 4/80 - Services utilisant la communication de courte portée, p.ex. la communication en champ proche, l'identification par radiofréquence ou la communication à faible consommation d’énergie

Abrégé

Techniques for patient population flow modeling are disclosed, where such modeling can provide insights for future trends among a patient population, e.g., to facilitate allocation of resources for the patient population or to inform treatment recommendations for patients. A flow model can be used on dialysis patient populations where the patients are grouped into a compartment according to a certain criterion (or given criteria), where each compartment corresponds to the number of patients in each group, and where the number of compartments can vary depending on the given criteria. A model can then be used to describe the transition rates between the different compartments, as well as influx and efflux within each compartment. Such a model can be used, by way of example, to investigate the impact of sodium-glucose co-transporter 2 (SGLT2) inhibitors on the population dynamics of end-stage renal disease patients.

Classes IPC  ?

• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
• G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux

Abrégé

222RD), and determining predicted patient information using the acid-base model. Other embodiments are described.

Classes IPC  ?

• G16H 20/17 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients administrés par perfusion ou injection
• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

A medical device configured to prevent bug infestation is disclosed. The medical device may be a dialysis machine (e.g., a peritoneal dialysis machine) for conducting dialysis treatments. The medical device (e.g., dialysis machine) including an ultrasonic generator and emitter arranged and configured to emit an ultrasonic high frequency sound to prevent bug infestation.

Classes IPC  ?

• A01M 29/18 - CAPTURE OU PIÉGEAGE DES ANIMAUX OU ÉPOUVANTAILS; APPAREILS DE DESTRUCTION D'ANIMAUX OU DE PLANTES NUISIBLES Épouvantails ou dispositifs répulsifs, p.ex. pour oiseaux utilisant des ondes sonores utilisant des signaux ultrasonores

Abrégé

A system and method is provided for generating simulated dialysis treatment files. For instance, a computing device may obtain information such as general patient information, dialysis prescription information, and dialysis treatment information. The computing device may generate a dialysis treatment file based on the obtained information, and use the dialysis treatment file to verify and test an enterprise system. For instance, the generated dialysis treatment file may be used to ensure the enterprise system is functioning properly.

Classes IPC  ?

• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
• G05B 17/00 - Systèmes impliquant l'usage de modèles ou de simulateurs desdits systèmes
• G05B 17/02 - Systèmes impliquant l'usage de modèles ou de simulateurs desdits systèmes électriques
• G06F 9/451 - Dispositions d’exécution pour interfaces utilisateur
• G06F 11/36 - Prévention d'erreurs en effectuant des tests ou par débogage de logiciel

Abrégé

The present teachings include techniques for securing a connection to a dialyzer or the like e.g., securing the junction between a dialyzer port and a connector (e.g., a DIN connector) that couples the port to tubing of an extracorporeal circuit of a hemodialysis system. To this end, a locking device may engage both a DIN connector and a portion of the dialyzer, such as the cap or an adapter engaged therewith. The locking device may include an interior void sized and shaped to accommodate winged portions (or other portions) of the DIN connector to mitigate rotation thereof relative to the port to which it is engaged. Further, the locking device may be used to ensure that coupling between the DIN connector and the port is proper and secure. In this manner, a locking device can mitigate leaks, which can be catastrophic during a hemodialysis treatment or the like.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61M 39/10 - Raccords ou accouplements pour tubes

Abrégé

A system and method is provided for training operators (e.g., users), including new nurses or nephrologists as well as patients or their family members, to learn the intricacies of dialysis (e.g., hemodialysis) treatment through a simulation. The simulation may afford users the ability to fail catastrophically in simulated dialysis treatment, see the consequences, learn and internalize complex algorithms, and develop the ability to think in a time pressured situation. The simulation may thereby provide a safe learning environment for experiencing decisions and consequences of these decisions when performing a dialysis treatment. In some instances, the simulation may be in a mobile application form factor to encourage more ubiquitous use on personal devices, which may provide ease of access for the dialysis training. The simulation may further include time -based simulated scenarios that increase in difficulty and complexity between levels.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A63F 13/45 - Commande de la progression du jeu vidéo
• A63F 13/58 - Commande des personnages ou des objets du jeu en fonction de la progression du jeu en calculant l’état des personnages du jeu, p.ex. niveau de vigueur, de force, de motivation ou d’énergie
• G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p.ex. dispositif en vraie grandeur pour la démonstration pour la médecine
• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local

Abrégé

A method includes receiving, by a processor of a dialysis machine, a dialysate flow rate, a bicarbonate setting value, a signal from a pressure sensor configured to measure a pressure within a container, and a signal indicating a state of a fill valve; determining, based on the signal received from the pressure sensor and the state of the fill valve, fill parameters; determining a volume of the container based on at least two of the fill parameters; determining a depletion time in which the concentrate will be depleted from the container based on the volume of the container, the dialysate flow rate, and the bicarbonate setting value; determining, based on the depletion time, an amount of time remaining before the concentrate will be depleted from the container; and causing the dialysis machine to indicate the amount of time remaining before the concentrate will be depleted from the container.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

Apparatuses comprising at least one processor and a memory coupled to the at least one processor, wherein the memory comprises instructions that when executed by the processor cause the processor to access prescription information for a peritoneal dialysis (RD) process for a patient and provide the prescription information as input to at least one computational model to determine a predicted intraperitoneal volume (IPV) or a predicted ultrafiltration volume (UFV) respectively, wherein the computational model is trained to determine the predicted IPV or UFV respectively based on the prescription information and patient information for at least one RD process cycle for the patient or a population of patients associated with the patient.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61B 5/107 - Mesure de dimensions corporelles, p.ex. la taille du corps entier ou de parties de celui-ci

Abrégé

In one aspect, a peritoneal dialysis (PD) system includes a housing that receives a disposable cassette, a plurality of pinch valves that receive respective sections of fluid tubing of the disposable cassette, an air port that forms an airtight seal with an air line of the disposable cassette, an air pump that alternatingly pushes air out of the air port and pulls air in from the air port, and a computer processor that controls the plurality of pinch valves and the air pump such that the cassette performs a dwell phase in which the diaphragm pump pumps fresh dialysate from a dialysate bag to a heater bag, a fill phase in which the diaphragm pump pumps the fresh dialysate from the heater bag to a patient line, and a drain phase in which the diaphragm pump pumps spent dialysate form the patient to a drain.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale

Abrégé

The present disclosure relates to a system for predicting the magnitude of ultrafiltration volume expected in a peritoneal dialysis treatment for an individual patient, the system comprising: - a peritoneal treatment machine configured to perform cycles of a peritoneal treatment performed on the patient according to a prescription by controlling at least one actuator and/or valve of the peritoneal treatment machine, the cycles comprising a fill phase, a dwell phase and a drain phase, - a sensor for repeatedly measuring a sensed value during the treatment performed on the patient, - a controller programmed to predict the magnitude of ultrafiltration volume expected during a treatment performed according to a prescription based on a model of ultrafiltration, and to fit parameter values of the model to the individual patient based on the values measured by the sensor,wherein the model of ultrafiltration uses a patient-specific aggregated reflection coefficient as a parameter representing the overall average effect of different pores of the peritoneum and of different solutes present in the peritoneal cavity and the blood plasma on the differential crystalloid osmotic pressure between the peritoneal cavity and blood plasma.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

The exemplary embodiments may provide a software tool that enables a software designer to derive a color from a reference color. The software designer may specify changes in color characteristics that are to be applied to the reference color to derive the desired color. The user interface may be provided to allow the software designer to enter information regarding the reference color and the desired changes in color characteristics. The user interface may display the reference color and that resulting desired color so that the software designer may get a visual appreciation for the difference in the colors. The software tool of the exemplary embodiments may also include a color palette generator. The color palette generator may generate a palette of colors from a reference color.

Classes IPC  ?

• G06F 8/38 - Création ou génération de code source pour la mise en œuvre d'interfaces utilisateur
• G06F 8/34 - Programmation graphique ou visuelle
• G06F 9/451 - Dispositions d’exécution pour interfaces utilisateur
• G06F 3/0481 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] fondées sur des propriétés spécifiques de l’objet d’interaction affiché ou sur un environnement basé sur les métaphores, p.ex. interaction avec des éléments du bureau telles les fenêtres ou les icônes, ou avec l’aide d’un curseur changeant de comport
• G06F 3/04847 - Techniques d’interaction pour la commande des valeurs des paramètres, p.ex. interaction avec des règles ou des cadrans
• G06F 3/04845 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p.ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs pour la transformation d’images, p.ex. glissement, rotation, agrandissement ou changement de couleur

Abrégé

A hemodialysis system including one or more ultraviolet chambers is disclosed. The hemodialysis system including a dialyzer arranged and configured to filter a patient's blood, a hemodialysis machine arranged and configured to pump, move, or the like dialysate through the dialyzer, the hemodialysis machine including an outlet valve and an outlet fluid flow path to pump or move dialysate from the hemodialysis machine to the dialyzer, and an inlet valve and an inlet fluid flow path to pump or receive dialysate from the dialyzer, and one or more ultraviolet chambers arranged and configured to kill bacteria, viruses, or a combination thereof. Thus arranged, by incorporating one or more ultraviolet chambers in strategic areas of the system, the ultraviolet chambers may eliminate, or at least greatly reduce, the possibility of cross-contamination in, for example, the dialysate, and thus eliminate the need for disinfecting the system between treatments.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

Compounds, systems, kits, methods, and/or apparatuses may be operative to reduce amyloid beta (A0) peptide in a patient, including a central nervous system (CNS) of the patient and/or a periphery (non-CNS portion) of the patient. In some embodiments, a displacer fluid comprising an A0 displacer may be introduced to the patient to bind to a blood protein, such as albumin, that binds A0 (for instance, A0 peptide or non-plaque A0 in the patient periphery. Binding of the displacer to the blood protein may facilitate more free A0 peptide (for instance, A0 monomers) in the periphery for clearance via natural processes, such as through the liver or kidneys, and/or artificial processes, such as dialysis. Increased removal of the free A0 peptide in the periphery may ultimately lead to less A0 peptide in the CNS, which may decrease A0 plaque formation in Alzheimer's Disease (AD) patients. Other embodiments are described.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation

Abrégé

Techniques for monitoring intraperitoneal volume (IPV) during a dwell period of a peritoneal dialysis patient include monitoring intraperitoneal pressure (IPP) during the dwell period using a pressure sensor, monitoring the density of the dialysate during the dwell period, and determining a change in IPV based at least on a change in IPP and a change in the density of the dialysate during the dwell period.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale

Abrégé

A leak detector is provided that is incorporated into the wheels of a moveable medical device and/or cart or cabinet therefor. By incorporating a leak detector into the wheels themselves of the movable medical device, the leak detector, despite movement of the medical device, is suitably located to locate leaks with respect to the medical device at all times and requires no additional setup. The leak detector can further be tested by and interface with the moveable medical device to ensure the leak detector is in working condition and provide a convenient interface for a user. Additionally, by using this technology on each of the multiple wheels of a moveable medical device, the detectable area may be bigger than a leak detector at only one location.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61M 1/28 - Dialyse péritonéale
• A61B 50/13 - Chariots

Abrégé

A method includes flowing spent dialysate through a spent dialysate line of a dialysis system into a fluid receptacle fluidly coupled to the spent dialysate line, reacting the spent dialysate with a chemical reagent contained within the fluid receptacle to generate a reacted sample, emitting electromagnetic radiation through the reacted sample using an emitter; detecting a level of one or more waste products present in the spent dialysate using a spectroscopy sensor positioned proximate the fluid receptacle.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

A detector assembly configured for use in a dialysis (e.g., a hemodialysis) system is disclosed herein. The detector assembly including a wetness detector configured to detect blood, fluid, a leak, etc. The detector assembly being operatively coupled to, and more preferably, including an inertial measurement unit (IMU). Thus arranged, the detector assembly is configured to measure, read, obtain, provide, etc. additional information or data during a dialysis treatment, which information or data can be transmitted and/or used to, for example, provide greater insight into the system and/or to make better decisions. In one embodiment, the detector assembly can be used to determine when and how a patient is moving and feed that information back to the dialysis machine. In use, the information or data can be used in combination with other information to make an improved determination as to the requirement for an alert and/or stoppage of the dialysis treatment.

Classes IPC  ?

• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre

Abrégé

The present teachings may generally include a first fluid connector that includes a first body having a first central cavity that defines a first fluid pathway and a first seal within the first central cavity. The first seal includes a pair of first interfacing elements positioned adjacent one another at a distal end of the first seal and a first opening configured to remain sealed closed when the first interfacing elements are adjacent, and the first opening opens when the first interfacing elements are separated. The first connector is configured to fluidly connect to a second connector by engaging the first interfacing elements and with a pair of second interfacing elements of the second connector, thereby causing both pairs of first and second interfacing elements to separate causing the opening of first opening and second opening.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale
• A61M 39/00 - Tubes, raccords ou accouplements pour tubes, soupapes, voies d'accès ou similaires, spécialement adaptés pour un usage médical
• A61M 39/10 - Raccords ou accouplements pour tubes
• A61M 39/26 - Soupapes se fermant automatiquement après déconnexion et s'ouvrant lors de la reconnexion
• A61M 39/28 - Moyens de serrage pour l'écrasement des tubes flexibles, p.ex. brides de serrage à rouleaux

Abrégé

The described technology may include processes to model parathyroid gland (PTG) functionality and/or calcimimetic administration to healthy subjects and/or patients with a health abnormality that affects PTG function. In one embodiments, a computer-implemented method of calcimimetic analysis of PTG functionality may include accessing a calcimimetic model configured to simulate a functionality of a PTG of at least one patient, the calcimimetic model comprising at least one of a pharmacokinetic model or a pharmacodynamic model, providing a calcimimetic administration of a calcimimetic to the at least one patient via the calcimimetic model according to an administration process, and determining calcimimetic information based on the calcimimetic administration via the calcimimetic model for the at least one patient, the calcimimetic information configured to indicate an efficacy of the calcimimetic administration. Other embodiments are described.

Classes IPC  ?

• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• G01N 33/74 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des hormones
• G16B 5/00 - TIC spécialement adaptées à la modélisation ou aux simulations dans la biologie des systèmes, p. ex. réseaux de régulation génétique, réseaux d’interaction entre protéines ou réseaux métaboliques
• G16C 20/10 - Analyse ou conception des réactions, des synthèses ou des procédés chimiques

Abrégé

A method includes collecting used dialysis fluid in a container and combining the dialysis fluid with an acid to lower the pH value of the used dialysis fluid.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61J 1/10 - Récipients du type sac
• A61J 1/20 - Dispositions pour le transfert des liquides, p.ex. du flacon à la seringue
• A61L 2/00 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contact; Accessoires à cet effet
• A61M 1/28 - Dialyse péritonéale
• C02F 1/66 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par neutralisation; Ajustage du pH
• C02F 9/00 - Traitement en plusieurs étapes de l'eau, des eaux résiduaires ou des eaux d'égout

Abrégé

A computer-implemented method, a medical device, and a system for acquiring user-specific customization data, i.e. user-specific language packages, are provided. The computer-implemented method comprises: determining a first set of user-specific customization data stored on the medical device; comparing the first set of user-specific customization data with a second set of user-specific customization data that is required by a user; and upon determining that the second set of user-specific customization data is different from the first set of user-specific customization data, acquiring, from a data storage external to the medical device, the second set of user-specific customization data or a delta between the first set and the second set of user-specific customization data.

Classes IPC  ?

• G16H 40/60 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
• G06F 3/048 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI]

Abrégé

This disclosure relates to medical fluid pumping systems and related devices and methods. In some aspects, a blood treatment system includes a user interface; a processor in communication with the user interface and configured to perform operations including: presenting instructions on the user interface, the instructions pertaining to at least one modality of a set of modalities, wherein the set of modalities include hemodialysis (HD), hemofiltration (HF), and hemodiafiltration (HDF), wherein the instructions pertain to a component of a blood treatment machine of the blood treatment system; receiving information associated with the component of the blood treatment machine; and eliminating modalities from the set of modalities to determine a modality of the blood treatment machine based on the received information.

Classes IPC  ?

• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour

Abrégé

A method for diagnosis, preferably quick diagnosis of peritonitis or a risk of peritonitis in a peritoneal dialysis subject, comprising: detecting H-NGAL protein in peritoneal dialysis effluent of the peritoneal dialysis subject, if H-NGAL protein is greater than or equal to a cutoff value, indicating that the subject has or is at a risk of peritonitis. A strip, a kit and a device used in the method, and the use of a molecule that specifically binds to H-NGAL protein in the preparation of a composition, a strip or a kit for diagnosis, preferably quick diagnosis of peritonitis by detecting H-NGAL protein in peritoneal dialysis effluent of a peritoneal dialysis subject.

Classes IPC  ?

• G01N 33/543 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
• G01N 33/573 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour enzymes ou isoenzymes
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
• A61M 1/28 - Dialyse péritonéale

Abrégé

A medical fluid line connector includes a body defining a central opening extending therethrough, a first projection extending from a first portion of the body, and a second projection extending from a second portion of the body, the second projection being circumferentially and axially offset from the first projection. The first portion of the body and second portion of the body are configured to separate from one another in response to a threshold amount of force being applied to the first projection and the second projection to rotate the first portion of the body and second portion of the body relative to one another.

Classes IPC  ?

• A61M 39/10 - Raccords ou accouplements pour tubes

Abrégé

The described technology may include processes to model renal pathophysiology in patients and/or patient populations. In one embodiment, a method may include a CKD/ESRD condition analysis, such as a vascular calcification analysis. The method may include, via a processor of a computing device: determining a vascular calcification model configured to model vascular calcification of a virtual patient to determine a causal relationship between at least one patient characteristic and a vascular calcification indicator, and generating a causal relationship structure configured to visualize a causal relationship between the at least one patient characteristic and the vascular calcification indicator. Other embodiments are described.

Classes IPC  ?

• G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients
• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux

Abrégé

The present teachings include analyzing oxygen saturation levels sensed during a hemodialysis treatment for a patient to determine whether the patient has a medical condition based on hypoxemia, apnea, or the like experienced during the treatment. To this end, the present teachings may include the use of a machine-learning algorithm trained to identify a presence of a high-frequency intermittent pattern that would be formed in a plot of the oxygen saturation levels, e.g., to determine a severity of respiratory instability experienced. The present teaching may also or instead include a time-series analysis including at least one of: (i) calculating recurrence-based quantification, such as, but not limited to, recurrence rate, determinism, and laminarity; (ii) calculating the optimal recurrence threshold based on maximum variations of the system's determinism and degree of predictability; and (iii) calculating complexity-based measures such as permutation entropy. Such analyses may be used to detect, inter-alia, sleep apnea syndrome.

Classes IPC  ?

• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation
• A61M 39/02 - Voies d'accès

Abrégé

This disclosure relates to symmetric tubing clamps for blood treatment systems and related systems and methods. In some aspects, a tubing clamp includes a resilient body that has symmetry with respect to a first plane with a normal along a longitudinal axis of the resilient body, the resilient body comprising a sidewall defining an opening such that a tubing is arrangeable through the opening along the longitudinal axis of the resilient body; first and second snap-fit features configured to engage with each other when the resilient body is compressed along a direction transverse to the longitudinal axis; and a protrusion configured to constrict the tubing when the resilient body is compressed along the direction transverse to the longitudinal axis.

Classes IPC  ?

• A61M 39/28 - Moyens de serrage pour l'écrasement des tubes flexibles, p.ex. brides de serrage à rouleaux
• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang

Abrégé

An extracorporeal blood treatment device and a method are provided for removing a secondary membrane formed on a semipermeable membrane of a dialyzer during an extracorporeal blood treatment. The extracorporeal blood treatment device operates in a first operating mode in which a dialysate outlet valve is open such that dialysate flows through a dialyzer feed line, through a dialysate chamber, and into and through a dialyzer discharge line. The extracorporeal blood treatment device operates in a second operating mode to remove the secondary membrane from the semipermeable membrane. During the second operating mode, the dialysate outlet valve is closed for a duration of time such that dialysate is prevented from flowing through the dialyzer discharge line. A backflush procedure results wherein a volume of dialysate passes from the dialysate chamber through the semipermeable membrane and into the blood chamber.

Classes IPC  ?

• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

The present invention relates to a method to make polymeric membranes that are preferably useful in dialysis, wherein the method conducts at least one membrane-forming step and/or post-forming processing step with the use of sonication. Polymeric membrane, such as polymeric hollow fiber membrane, having improved one or properties are further described.

Classes IPC  ?

• B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
• B01D 69/08 - Membranes à fibres creuses

Abrégé

A mechanical lift includes a housing defining a series of vertical adjustment notches, an adjustment block disposed within the housing, a hook extending from the adjustment block and configured to support a hanging load, a stopper supported by the adjustment block and movable between retracted and extended positions, and a spring disposed within the housing and exerting an upward force against the adjustment block to mechanically lift the adjustment block and the hook extending therefrom from a first vertical position at a first notch of the series of vertical adjustment notches to a second notch of the series of vertical adjustment notches when the stopper is in the retracted position. In the retracted position, the stopper is disengaged from the housing. In the extended position, the stopper is engaged with a selected notch to lock a vertical position of the adjustment block and the hook extending therefrom.

Classes IPC  ?

• A61M 5/14 - Dispositifs de perfusion, p.ex. perfusion par gravité; Perfusion sanguine; Accessoires à cet effet
• A61G 7/05 - Lits spécialement conçus pour donner des soins; Dispositifs pour soulever les malades ou les personnes handicapées - Parties constitutives, détails ou accessoires de lits

Abrégé

In one aspect, a medical device includes: a housing; a plurality of attachment points disposed on a face of the housing and configured to hold a medical fluid tubing system; a lighting system disposed at or below the face of the housing; and a processor configured to control the lighting system to (a) visually indicate the locations of the attachment points and (b) in response to a feedback signal indicating whether or not the medical fluid tubing system is attached to at least one of the attachment points, alter the visual indication of the lighting system.

Classes IPC  ?

• G16H 20/60 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant le contrôle de l’alimentation, p.ex. les régimes
• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• G16H 20/17 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients administrés par perfusion ou injection
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
• G16H 70/20 - TIC spécialement adaptées au maniement ou au traitement de références médicales concernant des pratiques ou des directives

Abrégé

A connected health system includes an instant user feedback interface that captures meaningful feedback from medical patients, such as dialysis patients, when they are most apt to provide it. The system enables a patient to speak freely with comments or questions about their dialysis experience at the time that the comments or questions arise. Accordingly, the system described herein facilitates and invites the providing of user feedback by voice input, along with relevant treatment and system status information, in a secure way to improve user experience and to help in machine development using simple and easily accessible interface buttons. By providing a conduit for instant user feedback, that may be provided along with relevant treatment and/or system status information that has caused the user feedback, the system described herein may improve the way the patient feels about interactions with the company and their dialysis machines and services.

Classes IPC  ?

• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p.ex. pour la gestion du personnel hospitalier ou de salles d’opération
• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
• G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance

Abrégé

A delivery robot is provided for the delivery of home dialysis supplies to a home dwelling of a home dialysis patient. The delivery robot can be an autonomous delivery robot. The delivery robot can have an outdoor set of wheels or other traction devices, and an indoor set of wheels or other traction devices. The delivery robot can be configured to switch between an outdoor configuration for traversing an outdoor surface, and an indoor configuration for traversing an inside surface, inside the home of the home dialysis patient. A network is also provided and can include a robot delivery vehicle, a warehouse, a remote computer within the patient' s home, or a combination thereof. Methods of delivering home dialysis supplies are also provided that utilize the delivery robot and network.

Classes IPC  ?

• B25J 11/00 - Manipulateurs non prévus ailleurs
• B25J 5/00 - Manipulateurs montés sur roues ou sur support mobile
• B60B 19/02 - Roues non prévues ailleurs ou ayant des caractéristiques précisées dans l'un des sous-groupes du présent groupe transformables, p.ex. de roues routières en roues ferroviaires; Roues spécialement prévues pour emploi alternatif sur route et sur rail
• B60B 11/02 - Ensembles de roues distinctes montées pour rotation indépendante ou couplée
• B25J 19/00 - Accessoires adaptés aux manipulateurs, p.ex. pour contrôler, pour observer; Dispositifs de sécurité combinés avec les manipulateurs ou spécialement conçus pour être utilisés en association avec ces manipulateurs
• G05D 1/02 - Commande de la position ou du cap par référence à un système à deux dimensions
• G06Q 10/08 - Logistique, p.ex. entreposage, chargement ou distribution; Gestion d’inventaires ou de stocks
• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• B60P 3/06 - Véhicules adaptés pour transporter, porter ou comporter des charges ou des objets spéciaux pour le transport de véhicules

Abrégé

This disclosure relates to a system for supporting a peritoneal dialysis fluid bag and to a method to detect a bag leak. The system includes a curved tray configured to support a medical fluid bag during peritoneal dialysis, the curved tray comprising a plurality of openings therethrough, a medical fluid collection basin removably coupled to the curved tray and configured to collect medical fluid leaked from the bag, a leak detector coupled to a surface of the medical fluid collection basin and configured to detect fluid as leaked from the medical fluid bag into the medical fluid collection basin, and a control unit configured to receive treatment data related to the medical treatment.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale

Abrégé

A medical device, such as a dialysis machine, may be equipped with a focused directional speaker system and/or displays to direct audible and visual alarms towards a patient in order to minimize disruption to others caused by an alarm. The speaker system may be useful for home dialysis patients whose alarming devices at night wake up not only their partners but also neighbors, especially when the patient is hard of hearing or a heavy sleeper and needs to set the volume at the loudest setting in order to hear it. Further implementation and safety features may provide that, if the patient still does not awaken after a set amount of time to clear the alarm, then the dialysis device broadcasts the alarm to the entire room.

Classes IPC  ?

• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/28 - Dialyse péritonéale

Abrégé

This disclosure relates to medical fluid cassette leak detection methods and devices. In some implementations, a method of detecting micro-leaks in a medical fluid cassette, the method includes decreasing a pressure between a vacuum reservoir of a medical treatment machine and a membrane of the medical fluid cassette when the medical fluid cassette is coupled to the medical treatment machine; measuring, using a flow meter, a rate of net fluid flow between the vacuum reservoir and the membrane of the medical fluid cassette; determining that the rate of net fluid flow between the vacuum reservoir and the membrane of the medical fluid cassette is above a threshold value; and in response to determining that the rate of net fluid flow is above the threshold value, causing the medical treatment machine to take a particular action.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale

Abrégé

A system and method for measuring edema, at home, is provided, along with a measuring pattern for use therewith. The system includes a computing system that has an imaging device, a processor, a memory, and a wireless transmitter. The computing system is configured to capture edema data of a patient and send the data to a remote doctor. The pattern can be incorporated into a flexible sheet substrate that can be placed over a portion of a patient's skin. By pressing the flexible sheet substrate into the patient, a depression is formed and the pattern is distorted. The imaging device captures an image of the depression and the distorted pattern. The computing system processes the image and determines a depth of the depression based on the distortion of the pattern.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/107 - Mesure de dimensions corporelles, p.ex. la taille du corps entier ou de parties de celui-ci
• A61M 37/00 - Autres appareils pour introduire des agents dans le corps; Percutanisation, c. à d. introduction de médicaments dans le corps par diffusion à travers la peau

Abrégé

Described are a number of aptamers that are specific to bind with lipopolysaccharide (LPS), and associated methods

Classes IPC  ?

• C12N 15/115 - Aptamères, c. à d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus

Abrégé

Described are a number of aptamers that are specific to bind with lipoteichoic acid (LTA), and associated methods

Classes IPC  ?

• C12N 15/115 - Aptamères, c. à d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus

Abrégé

Described are a number of aptamers that are specific to bind with peptidoglycan ("PGN") with specificity over counter-targets lipopolysaccharides ("LPS") and lipoteichoic acid ("LTA"), and associated methods.

Classes IPC  ?

• C12N 15/115 - Aptamères, c. à d. acides nucléiques liant spécifiquement une molécule cible avec une haute affinité sans s'y hybrider
• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus

Abrégé

Systems and methods for device troubleshooting processes based on computational models are described. In one example, an apparatus may include at least one processor and a memory coupled to the at least one processor. The memory may include instructions that, when executed by the at least one processor, may cause the at least one processor to determine abnormal event information associated with an abnormal event active on the device, and determine, via a computational model: a diagnosis of a device problem based on the abnormal event information, and at least one resolution to resolve the device problem. Other embodiments are described.

Classes IPC  ?

• G05B 23/02 - Test ou contrôle électrique
• G06V 10/00 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos

Abrégé

Methods, apparatuses, and systems for determining patient dialysis profiles, for example, of peritoneal transport status or disease progression, are described. For example, in one embodiment, a method of determining a patient profile of a dialysis patient may include obtaining a volume of fluid associated with the dialysis patient, generating patient information via fluorescence analysis of the patient fluid, and determining the patient profile based on evaluating the patient information with a profile library, the patient profile comprising at least one of a peritoneal transport status classification or a disease progression. Other embodiments are described

Classes IPC  ?

• G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p.ex. pour des analyses d’échantillon de patient
• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux

Abrégé

A circuit for measuring the conductivity of a medical fluid, the circuit comprising: a data collecting cell through which a medical fluid is configured to flow; an input voltage source that provides an input voltage to the data collecting cell; a voltage measurement unit configured to measure the input voltage and an output voltage of the data collecting cell; and a switch in communication with the voltage measurement unit, the switch configured to switch between a first state in which the voltage measurement unit is configured to measure the input voltage and a second state in which the voltage measurement unit is configured to measure the output voltage of the data collecting cell.

Classes IPC  ?

• G01N 27/04 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance
• G01N 27/08 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la résistance d'un liquide qui coule sans interruption

Abrégé

A mobile cart for a medical device is disclosed. The cart is designed to transport a medical device such as a dialysis machine (e.g., a peritoneal dialysis (PD) machine). The medical device can be connected to a power supply included in the cart, where the power supply includes one or more energy storage devices (e.g., batteries), a charging circuit, and (optionally) an inverter. The cart can also include a number of features such as automatic brakes, UV light sterilization, sensors such as object detection safety features, environmental sensors, and the like. The cart can include electronic components that enables certain functionality such as hosting a wireless local area network or communicating wirelessly with the medical device. A docking station is also disclosed that enables wireless charging of the power supply such that neither the medical device nor the cart needs to be plugged into an external power supply.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale
• B61B 1/00 - Aménagement général des gares, des quais ou des voies de garage; Réseau des voies ferrées; Systèmes de triage des véhicules ferroviaires

Abrégé

A method for detecting occult hemorrhages is provided. The method comprises: obtaining, by a medical system comprising a blood monitoring system, a first hematocrit concentration prior to infusing a saline solution into a bloodstream of the patient; infusing, by the medical system, the saline solution into the bloodstream of the patient; obtaining, by the medical system, a second hematocrit concentration after infusing the saline solution into the bloodstream; determining, by the medical system, a first absolute blood volume based on the first hematocrit concentration and the second hematocrit concentration; generating, by the medical system, a notification indicating a potential occult hemorrhage based on the first absolute blood volume and a pre-defined absolute blood volume threshold; and providing, by the medical system, the notification indicating the potential occult hemorrhage.

Classes IPC  ?

• A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

A thermal protection system configured for use with a dialysate container or bag in a dialysis system is disclosed. The thermal protection system being configured so that when the dialysate container is subjected to a temperature greater than a predetermined temperature such as, when the dialysate container is heated within a microwave oven, the thermal protection system is configured to (i) prevent the flow of dialysate from the bag, (ii) indicate that the dialysate container has been subjected to a temperature greater than the predetermined temperature, or (iii) a combination thereof. In one embodiment, the thermal protection system is a circular hollow ring positioned within an exit port of the bag, the ring melting upon reaching the predetermined temperature to block the flow of dialysate. Alternatively, and/or in addition, the thermal protection system may be a thermally sensitive dye configured to change color upon being subjected to the predetermined temperature.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

A lightweight inflatable vest is provided with embedded listening devices. Once inflated, the vest enables a physician to hear amplified lung sounds and heart beats and rhythms of a patient wearing the vest, via connection to a smart phone application, through a patient portal, or the like. By using the device on a patient, a physician is provided with an accurate way to perform a respiratory and heart health assessment of the patient during a telehealth visit.

Classes IPC  ?

• A61B 7/04 - Stéthoscopes électriques
• A61B 7/02 - Stéthoscopes
• A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
• A41D 1/04 - Gilets, chandails, sweaters ou similaires
• A41D 1/00 - Vêtements
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale

Abrégé

A medical system, comprising: a medical machine; and a gateway device configured to communicate with the medical machine to allow access to a network, the gateway device comprising a data allowance and limitation unit that is configured to limit communication between the medical machine and the network when the data allowance and limitation unit is in an open state, wherein the data allowance and limitation unit is placed in the open state when a plannable system event occurs, and wherein, while in the open state, the data allowance and limitation unit is placed in a closed state when an unplanned event occurs, thereby providing less limited communication between the medical machine and the network compared to the open state.

Classes IPC  ?

• H04M 1/14 - Supports d'appareils, p.ex. comportant des repose-bras avec des moyens élastiques pour supprimer les vibrations externes
• G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance

Abrégé

An apparatus used in analyzing spent dialysate includes: at least one surface configured to accommodate a dialysate drain bag or drain line in a predetermined position; a light source positioned to emit light through the dialysate drain bag or drain line; and a light sensor positioned to sense light emitted by the light source through the dialysate drain bag or drain line.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• G01N 33/487 - Analyse physique de matériau biologique de matériau biologique liquide
• C12Q 1/06 - Détermination quantitative

Abrégé

The described technology may include treatment processes to increase the red blood cell (RBC) population of individuals, particularly chronic kidney disease (CKD) patients with renal anemia, by reducing an amount of Piezo1 chemical agonists in the blood of patients. In one embodiment, a method of treating a patient with renal anemia may include increasing RBC lifespan of an RBC population of the patient via reduction of a Piezo1 channel activation duration of at least a portion of the RBC population by reducing an amount of a target uremic compound in the blood of the patient, the target uremic compound having a form that prolongs the Piezo1 channel activation duration, wherein the amount of the target uremic compound may be reduced via selectively removing at least a portion of the target uremic compound from the blood of the patient. Other embodiments are described.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c. à d. hémofiltration, diafiltration
• G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique
• C07K 14/705 - Récepteurs; Antigènes de surface cellulaire; Déterminants de surface cellulaire

Abrégé

A hollow fiber membrane and methods of making the hollow fiber membrane are described. The membrane includes a hydrophobic polymer such as polysulfone, a hydrophilic polymer such as polyvinylpyrrolidone (PVP), and a fluropolymer additive, and optionally a stabilizer, for instance, to stabilize the fluoropolymer additive in the membrane, particularly during conditioning or E-beam sterilization or both. Further conditioning improvements to membrane manufacturing are disclosed. The membrane may be incorporated into a dialysis filter for use in hemodialysis and related applications. The membrane has improved hemocompatibility, charge stability, or middle molecule clearance compared to conventional membranes. Also disclosed is a method of evaluating membrane charge stability.

Classes IPC  ?

• B01D 61/24 - Dialyse
• B01D 61/28 - Appareils à cet effet
• B01D 63/02 - Modules à fibres creuses
• B01D 67/00 - Procédés spécialement adaptés à la fabrication de membranes semi-perméables destinées aux procédés ou aux appareils de séparation
• B01D 69/02 - Membranes semi-perméables destinées aux procédés ou aux appareils de séparation, caractérisées par leur forme, leur structure ou leurs propriétés; Procédés spécialement adaptés à leur fabrication caractérisées par leurs propriétés
• B01D 69/08 - Membranes à fibres creuses
• B01D 71/44 - Polymères obtenus par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone, non prévus dans un seul des groupes
• B01D 71/52 - Polyéthers
• B01D 71/68 - Polysulfones; Polyéthersulfones

Abrégé

Systems and methods for the image-based determination of the fluid status of a patient are described. In one example, an apparatus may include at least one processor and a memory coupled to the at least one processor. The memory may include instructions that, when executed by the at least one processor, may cause the at least one processor to receive an image that may include at least one image of a portion of a patient, determine fluid status information for the patient by processing the image via a trained computational model, the trained computational model trained based on at least one training image of the patient and a corresponding physical measurement of fluid status, the fluid status information indicating a current fluid status of the patient, and determine a treatment recommendation for the patient based on the fluid status information. Other embodiments are described.

Classes IPC  ?

• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine

Abrégé

A self-cannulation training system is provided that includes a cannulation pad, a simulated access, a simulated cannula, a control unit, and first and second indicators. The cannulation pad includes conductors for a cannulation electrical circuit and an infiltration electrical circuit. An insulating layer electrically insulates the conductors from one another. The simulated access connects to the cannulation electrical circuit and includes an electrically conductive material retained inside an outer sheath. The simulated cannula has an electrical conductor and connects to the control unit. The control unit has a power source that connects to both the cannulation electrical circuit and to the infiltration electrical circuit. The first indicator is activated when the cannula needle electrically completes the cannulation electrical circuit. The second indicator is activated when the cannula needle infiltrates and completes the infiltration electrical circuit. Methods of training a patient for self-cannulation, using the training systems, are also provided.

Classes IPC  ?

• G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p.ex. dispositif en vraie grandeur pour la démonstration pour la médecine
• G09B 19/24 - Emploi des outils
• A61M 5/42 - Dispositifs pour faire pénétrer des agents dans le corps par introduction sous-cutanée, intravasculaire ou intramusculaire; Accessoires à cet effet, p.ex. dispositifs de remplissage ou de nettoyage, appuis-bras avec des moyens pour insensibiliser la peau, pour soulever la peau en vue de faciliter la piqûre ou pour localiser le point du corps où la piqûre doit être effectuée

Abrégé

Enterprise organizations may use observational data to gather information about user experiences with their products and tools. For instance, patients with kidney failure may undergo dialysis treatment in order to remove toxins and excess fluids from their blood. The dialysis treatment may be performed at a hospital or clinic, or in a user's home, and the enterprise organization may use gathered information to gain understanding of user experiences with their dialysis machines and services. A user experience computing system gathers and processes user experience information from across the enterprise organization. Using stored observation data (e.g., surveys, studies etc.) in its smallest common form, the computing system may use this data as building blocks for creating more complex data objects (e.g. journey matrices and/or empathy gardens) using inputs from multiple different sources, and to facilitate presenting this information in an effective and empathetic way to product developers.

Classes IPC  ?

• G06Q 30/02 - Marketing; Estimation ou détermination des prix; Collecte de fonds

Abrégé

The disclosed devices for lateral flow testing may include a receptacle for receiving bodily fluids from a patient that has a predetermined fluid volume for application to one or more lateral flow test strips. A test strip holder may be positioned to receive the predetermined fluid volume of the bodily fluids from the receptacle. Various other components, devices, and methods are also disclosed.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes

Abrégé

A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a safety feature that enables the dialysis machine to automatically identify the connections made by a user in preparation for treatment. A smart connector is disclosed that uses a split RFID device that is operational when a first portion of the connector is mated to a second portion of the connector, and is not operational when the first portion is disconnected from the second portion. In an embodiment, the split RFID device incorporates an RFID chip in the first portion of the connector and an antenna in the second portion of the connector. In an embodiment, the RFID chip can store a tag that encodes information that indicates a formulation or a volume of a dialysis bag connected to the ports of a disposable cassette such that the dialysis machine can automatically discover the configuration of the dialysis setup.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

A dialysis access site monitoring system may generate a treatment recommendation for treating a condition of an access site based on a video of the access site. The dialysis access site monitoring system may operate to generate video information based on a video of a dialysis access site of a patient, determine change in the number of pixels (CNP) information of the video information, the CNP information associated with movement of a skin surface of the patient due to blood flow through the dialysis access site, determine frequency domain information of the CNP information, determine a maximum-to-median power (M2) value of the frequency domain information, and determine at least one access site characteristic based on the M2 value. The at least one access site characteristic may include access blood flow (ABF) and/or a prediction or estimation of stenosis. Other embodiments are described.

Classes IPC  ?

• G06T 7/00 - Analyse d'image
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/026 - Mesure du débit sanguin
• A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine

Abrégé

A light, such as an ultraviolet (UV) light, is used with a scanning test device in a scanning process of one or more of a user's hands to assess hand cleanliness according to a medical pre-treatment protocol for a medical treatment device, such as for a dialysis treatment using a home dialysis machine. If the scanning process results in a determination that the hands do not pass a cleanliness standard, the user is requested to perform a cleaning protocol and re-perform a scanning test. The scanning test device may be a smartphone, tablet device and/or other smart device running a software app that obtains and scans an image of the user's hand(s) illuminated by the UV light and makes an assessment of hand cleanliness according to an assessment algorithm. After passing the scanning test, the scanning test device signals to the treatment machine that the medical pre-treatment protocol may continue.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• G08B 21/24 - Alarmes aide-mémoire, p.ex. alarmes contre la perte
• A61B 90/80 - Instruments pour nettoyer ou laver la peau des chirurgiens ou des patients

Abrégé

A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a safety feature that is used to isolate individual fluid lines attached to a disposable cassette. The PD machine can include an interface for a disposable cassette, a plurality of safety mechanisms, and a processor. A plurality of fluid lines are connected to the disposable cassette, and each safety mechanism corresponds to a particular fluid line in the plurality of fluid lines. The processor is configured to detect a hazard condition, such as a loss of power to the PD machine or leak in the disposable cassette, and activate one or more safety mechanisms to isolate corresponding fluid lines connected to the disposable cassette. In one embodiment, the safety mechanisms are spring-loaded clamping mechanisms configured to compress a distensible tube connected to the fluid line. In another embodiment, the safety mechanisms include relay solenoids and/or check valves.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/28 - Dialyse péritonéale

Abrégé

Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments are disclosed. The dialysis system may include a dialysis machine for transferring dialysate to a patient from a dialysate source. The dialysate may flow from the dialysate source through a cartridge or cassette (e.g., a disposable cartridge or cassette) positionable within the dialysis machine. The dialysis machine includes a piston or pump for pumping fluid (e.g., dialysate) from the cassette to the patient. In various embodiments, the dialysis machine includes one or more sensors for monitoring a condition. For example, the dialysis machine may include sensor(s) for monitoring proper alignment of the cassette within the cassette compartment, or sensors mounted on the pump head for monitoring a leak during a dialysis operation, or sensors for monitoring improper operation of the pumps (e.g., pistons), or a combination thereof.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

Dialysis systems for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments are disclosed. The dialysis system may include a spent dialysate container for receiving spent dialysate from a patient. In use, the spent dialysate containers are arranged and configured to provide one or more mechanical advantages to ease disposal of the spent dialysate. For example, the spent dialysate container may receive the spent dialysate from the patient and enable the patient or caregiver to dispose of the spent dialysate without requiring the patient or caregiver to lift bags of spent dialysate or incorporate lengthy drain lines. The spent dialysate container may include a reservoir to receive the spent dialysate, wheels to enable the patient or caregiver to transport the reservoir, mechanisms to facilitate disposal of the spent dialysate from the reservoir, a nozzle to dispose of the spent dialysate, and/or a disinfectant to disinfect the drain.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61M 1/28 - Dialyse péritonéale
• B65F 3/00 - Véhicules particulièrement adaptés pour le ramassage des ordures
• A61B 50/13 - Chariots

Abrégé

The present teachings may generally include a sealing device disposed within a connector (e.g., a patient connector) at the end of catheter tubing, where the sealing device is structurally configured to form a releasable seal for the catheter tubing. That is, when unengaged with a contact portion of another connector or device, the sealing device may be disposed in a first position establishing a seal. Specifically, a channel disposed through the body of the sealing device may be obstructed when in this first position. However, through predetermined engagement with a contact portion of another connector or device, the sealing device may be moved (e.g., rotated) to a second position to establish a fluid pathway through the channel. And, when this predetermined engagement is removed, the sealing device may be structurally configured to automatically move back into the first position to reestablish the seal for the catheter tubing.

Classes IPC  ?

• A61M 25/00 - Cathéters; Sondes creuses
• A61M 39/26 - Soupapes se fermant automatiquement après déconnexion et s'ouvrant lors de la reconnexion
• A61M 39/22 - Soupapes ou agencement de soupapes

Abrégé

Techniques and apparatuses for determining an estimated cardiac output for a patient during dialysis treatment are described. In one embodiment, for example, an apparatus may include a memory and logic coupled to the memory. The logic may be configured to determine an upper body oxygen consumption for a patient, determine, during a dialysis process: a hemoglobin concentration and a venous oxygen saturation measured via an optical blood monitor operably coupled to an extracorporeal circuit of a dialysis system performing the dialysis process,; an arterial oxygen saturation measured via a pulse oximeter operably coupled to the extracorporeal circuit; an arterial-venous oxygen content difference based on the arterial oxygen saturation and the venous oxygen saturation; and an upper body blood flow (UBBF) as (upper body oxygen consumption)/(arterial-venous oxygen content difference), and determine a treatment recommendation based on the upper body blood flow. Other embodiments are described.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
• A61B 5/029 - Mesure du débit de sang à la sortie du cœur, p.ex. volume éjecté par minute
• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale

Abrégé

The hemostasis band (1) comprises a band (2), preferably made from an elastic material, a pressure focusing element (3) for focusing pressure generated by the band (2) to hold a cannula in place at a cannulation point, wherein the band (2) can be arranged in a loop and the size of the loop formed by the band (2) is adjustable to at least one defined size by means of an external tool (5), such as a torque driver. System of a hemostasis band (1) comprises an external tool (5) and a hemostasis band (1).

Classes IPC  ?

• A61B 17/132 - Tourniquets

Abrégé

Collection filter devices configured to filter peritoneal dialysis (PD) effluent draining from a patient during a PD process for collecting target materials, such as human cells, microorganisms, and/or other components from PD effluent. For instance, a filter device may be configured to be installed in-line in a drain circuit of a PD system using conventional tubing. The captured materials may be analyzed or otherwise processed to determine health characteristics of a patient and/or to capture stem cells.

Classes IPC  ?

• A61M 1/1619 -
• A61B 10/00 - Autres méthodes ou instruments pour le diagnostic, p.ex. pour le diagnostic de vaccination; Détermination du sexe; Détermination de la période d'ovulation; Instruments pour gratter la gorge

Abrégé

Described are assays, associated assay kits, and associated methods for diagnosing an infection in a subject. The assay includes a first binding molecule that specifically binds an inflammatory marker (i.e., neutrophil gelatinase-associated lipocalin (NGAL) homodimer) in a sample taken from 5 the subject, and a second binding molecule that binds a marker indicative of the presence of a pathogen in the sample. The assay and methods are for the diagnosis of peritonitis in peritoneal dialysis patients

Classes IPC  ?

• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The present teachings generally include devices, systems, kits, and methods for collecting, storing, and transporting specimens, e.g., in the context of pool testing. For example, the present teachings may include a compound swab featuring a first swab and a second swab, where the first swab can be detached for pool testing and the second swab can be preserved for testing based on results of the pool test. The present teachings may also or instead include a container having a separator structurally configured to separate swabs of a compound swab. Further, the present teachings may include a swab having a suction enhancer to promote the capture of a specimen on a collection tip thereof. The present teachings may also or instead include a receptacle that can house a plurality of swabs and sever at least a portion of the collections tips thereof, e.g., for pool testing.

Classes IPC  ?

• A61F 13/38 - Tampons comportant une poignée en forme de bâtonnet, p.ex. bâtonnets ouatés
• A61B 10/00 - Autres méthodes ou instruments pour le diagnostic, p.ex. pour le diagnostic de vaccination; Détermination du sexe; Détermination de la période d'ovulation; Instruments pour gratter la gorge
• A61B 10/02 - Instruments pour prélever des échantillons cellulaires ou pour la biopsie
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes

Abrégé

The present teachings generally include parabiotic dialysis systems and techniques. For example, the present disclosure includes parabiotic liver dialysis, e.g., for use in settings with limited resources. To this end, a parabiotic liver dialysis system may include a device having a semipermeable membrane with an average pore size that allows for the passage of albumin therethrough. In such a system, a first extracorporeal circuit may connect the device to the vascular system of a first animal (e.g., a liver patient), and a second extracorporeal circuit may connect the device to the vascular system of a second animal (e.g., a human with normal liver function), where the exchange of albumin therebetween is facilitated through the device. The present disclosure also includes various safety measures for parabiotic dialysis systems and techniques, such as biometric verification systems and techniques.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c. à d. hémofiltration, diafiltration
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation
• B01D 61/00 - Procédés de séparation utilisant des membranes semi-perméables, p.ex. dialyse, osmose ou ultrafiltration; Appareils, accessoires ou opérations auxiliaires, spécialement adaptés à cet effet

Abrégé

In one aspect, a method and system for detecting a change in fluid dynamics of a fluid flowing through an extra-corporeal circuit is disclosed, which includes establishing an acoustic wave resonance across a transverse dimension of at least a portion of a line associated with the extra-corporeal circuit through which the fluid flows, monitoring a phase signal of the resonant acoustic wave, and identifying occurrence of a change in fluid dynamics of the flowing fluid when the observed phase signal of the resonant acoustic wave indicates a deviation from the expected fluid flow signature. The change in fluid dynamics can be used to indicate a venous needle dislodgement event.

Classes IPC  ?

• G01S 5/18 - Localisation par coordination de plusieurs déterminations de direction ou de ligne de position; Localisation par coordination de plusieurs déterminations de distance utilisant des ondes ultrasonores, sonores ou infrasonores

Abrégé

The disclosed bag for mixing materials may include a front wall, a back wall, a mixing chamber between the front wall and the back wall, a first sidewall between the front wall and the back wall and defining a first side of the mixing chamber, a second sidewall between the front wall and the back wall defining a second, opposite side of the mixing chamber, and a port positioned to provide fluid access to the mixing chamber from a bottom of the mixing chamber, wherein the first sidewall and the second sidewall are shaped to alternate a direction of fluid flow when fluid is introduced into the mixing chamber through the port. Various other components, systems, and methods are also disclosed.

Classes IPC  ?

• B01F 15/00 - Accessoires pour mélangeurs
• B01F 13/08 - Mélangeurs magnétiques
• B01F 7/00 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins
• B01F 15/02 - Mécanismes d'alimentation ou d'évacuation
• B01F 11/00 - Mélangeurs avec mécanismes à secousses, oscillants ou vibrants

Abrégé

A secure artificial intelligence (AI) enabled wearable medical sensor platform is used for adaptive operation according to features and techniques described herein. Operational parameters are modified based on data inputs thereto that provide feedback to the AI systems of the wearable sensor platform. The described technology can facilitate adaptive optimizations provided by AI machine learning algorithms in a manner that can beneficially assist in the monitoring and treatment of a patient. For example, the system described herein may be used for the continuous monitoring of the physiological parameters and health of a patient's vascular access point (for example, the fistula) and may provide, among other things, early warnings of possible infection at the vascular access location.

Classes IPC  ?

• G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
• G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
• G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients

Abrégé

A dialysis machine (e.g., a peritoneal dialysis (PD) machine) can include a control unit configured to operate in a hybrid automated mode during a PD treatment. A processor in the control unit is configured to engage a pump during a fill phase of the PD cycle. The volume of fluid (e.g., dialysate) transferred to a patient line during the fill phase is monitored. After a dwell period, the pump is disengaged at the start of a drain phase of the PD cycle. Disengaging the pump can include: configuring valves of a disposable cassette to bypass the pump chambers of a disposable cassette; activating a bypass valve to shunt the patient line to a drain line; or moving a roller assembly of a peristaltic pump. The fluid transferred from the patient line to the drain line is monitored during the drain phase of the PD cycle..

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale

Abrégé

in silico in silico a plurality of virtual patients, wherein each of the virtual patients comprises a mathematical construct for modeling progression of osteoporosis via simulation of bone remodeling, said mathematical construct comprising a plurality of dynamic mathematical relations defining time-dependent evolution of at least one of a cell density variable or concentration variable associated with any of pre-osteoblasts, osteoblasts, preosteoclasts, osteoclasts, osteocytes, a bone resorption signal, sclerostin, estrogen, bone density and bone mineral content and employs a processor to determine time-variation of at least one of bone mineral density and bone mineral fraction based on at least a portion of said time- dependent variables, (b) applying a simulated therapy to said plurality of virtual patients, and (c) using said virtual patients to determine an effect of said simulated therapy on progression of osteoporosis.

Classes IPC  ?

• G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
• G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients

Abrégé

A home dialysis machine network is provided that includes a home dialysis machine and one or more walk-up service centers. The walk-up service center can be equipped with a diagnostic tool, parts, or supplies for the home dialysis machine. Methods of maintaining a home dialysis machine are also provided as are service centers equipped with a transportation service or office, a diagnostics department, an education and training department, a consultation department, an exercise and spa department, an entertainment department, a sales department, a repair shop, a new technologies department, a pharmacy, and a doctor's office.

Classes IPC  ?

• G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p.ex. pour la gestion du personnel hospitalier ou de salles d’opération
• G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments are disclosed. The dialysis system may include a dialysis machine for transferring dialysate to a patient from a dialysate source. The dialysate may flow from the dialysate source through a cassette (e.g., a disposable cassette) positionable within a port formed in the dialysis machine. The dialysis system may also include a cleaning cartridge insertable into the port. The cleaning cartridge may be arranged and configured to collect, remove, etc. any foreign material or debris from the port.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes

Abrégé

A medical device, such as a dialysis machine, may have multiple features and components that must be checked and attached prior to a treatment, and operators often lay tubing and other components on a surface after removing them from packaging. The system described herein provides a sterile work platform that is integrated with the medical device. In an example, the platform may be moveably coupled to the medical device. In a first position, the platform is positioned within or against the medical device, and, in a second position, the platform is extended from the medical device and disposed in a horizontal position. After the platform is extended to the second position, a surface of the platform is sterile and suitable to maintain aseptic technique for tubing and components placed on the platform. An information screen may be integrated into the platform and that provides information to an operator.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang

Abrégé

This disclosure relates to a blood treatment system including a blood treatment machine, a dialyzer configured to be coupled to the blood treatment machine, a blood line having a first end configured to be connected to the dialyzer and a second end configured to be connected to a needle for insertion into a patient, and one or more sensors operable to transmit, to the blood treatment machine, data related to tension along the blood line. The blood treatment machine is configured to take action in response to the data received from the one or more sensors.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation

Abrégé

A hemodialysis system includes: a hemodialysis machine configured to provide hemodialysis treatment to a patient, wherein the hemodialysis treatment includes circulating extracorporeal blood of the patient through an extracorporeal blood circuit; a first oxygen saturation sensor device configured to measure oxygen saturation corresponding to the extracorporeal blood of the patient in the extracorporeal blood circuit; a second oxygen saturation sensor device configured to measure oxygen saturation corresponding to blood flowing within the patient; and at least one controller configured to determine one or more oxygen saturation phase shift (OSPS) values or one or more transcutaneous travel time values corresponding to the patient based on oxygen saturation measurements from the first oxygen saturation sensor device and the second oxygen saturation sensor device.

Classes IPC  ?

• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale
• A61B 5/1459 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale invasifs, p.ex. introduits dans le corps par un cathéter
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation

Abrégé

A method for mitigating the spread of infectious diseases among dialysis patients is provided. The method comprises: receiving, by a prediction system and from a medical facility, individual treatment data indicating dialysis treatment information associated with a patient undergoing dialysis treatment; receiving, by the prediction system and from a blood testing laboratory, individual lab data indicating blood analysis information associated with the patient; determining, by the prediction system, disease analysis results for the patient based on inputting the individual treatment data and the individual lab data into a disease prediction machine learning (ML) model, wherein the disease analysis results indicate a likelihood of the patient being infected with a contagious disease; and providing, by the prediction system and to the medical facility, instructions indicating one or more responsive actions based on the disease analysis results.

Classes IPC  ?

• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
• G16H 50/80 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la détection, le suivi ou la modélisation d’épidémies ou des pandémies, p.ex. de la grippe
• G16H 20/17 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients administrés par perfusion ou injection

Abrégé

A hemodialysis system includes a hemodialysis machine and a blood monitoring system. The hemodialysis machine is configured to provide hemodialysis treatment to a patient, wherein the hemodialysis treatment includes circulating extracorporeal blood of the patient through an extracorporeal blood circuit. The blood monitoring system includes: a sensor device configured to measure a hematocrit value corresponding to the extracorporeal blood of the patient in the extracorporeal blood circuit; and at least one controller. The blood monitoring system is configured to communicate with an electronic health records (EHR) system over a communications network to obtain patient-specific mean corpuscular hemoglobin concentration (MCHC) data for the patient. The at least one controller is configured to determine a hemoglobin concentration value corresponding to the extracorporeal blood for the patient in the extracorporeal blood circuit using the measured hematocrit value and the patient-specific MCHC data for the patient.

Classes IPC  ?

• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang

Abrégé

A system for determining individualized dialysis prescriptions is provided. The system comprises a prescription recommendation server and an on-demand dialysis machine. The prescription recommendation server is configured to: receive, from a prescriber computing device, patient information associated with a new patient; determine, based on the patient information, an individualized dialysis prescription for the new patient, wherein the individualized dialysis prescription indicates a particular patient cluster associated with the new patient; and transmit, to an on-demand dialysis machine, the individualized dialysis prescription for the new patient. The on-demand dialysis machine is configured to: receive, from the prescription recommendation server, the individualized dialysis prescription for the new patient; and perform a dialysis treatment on the new patient based on the individualized dialysis prescription.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang

Abrégé

methods, apparatuses, and systems for determining a peritoneal transport status of a patient based on mass analyzing low volumes of peritoneal dialysis (PD) effluent to generate patient information that may be evaluated using PD effluent fingerprints to determine peritoneal transport characteristics of the patient are described. For example, in one embodiment, a method of determining a transport status of a dialysis patient may include obtaining a volume of peritoneal dialysis (PD) effluent of the dialysis patient, generating patient information via mass analysis of the volume of PD effluent, and determining patient profile information based on evaluating the patient information with a profile library, the patient profile information comprising a peritoneal transport status classification. Other embodiments are described.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale

Abrégé

Systems, methods, and/or apparatuses may be operative to perform a dialysis process that includes a displacer infusion process. In one embodiment, a method for determining a displacer compound may include constructing a plurality of target protein quantitative structure-activity relationship (QSAR) models, one for each of the plurality of binding sites, analyzing a set of candidate compounds using the plurality of QSAR models to determine a set of at least one potential compound with an affinity for binding to each of the plurality of binding sites, and selecting at least one displacer compound from the set of at least one potential compound. Other embodiments are described.

Classes IPC  ?

• G16C 20/30 - Prévision des propriétés des composés, des compositions ou des mélanges chimiques

Abrégé

The disclosed arterial chambers for hemodialysis may include a cap with a blood inlet port for conveying an intended patient's blood into the arterial chamber, an auxiliary port configured to provide fluid access to the arterial chamber, and a needleless access port configured to couple to a needleless syringe. The needleless access port may be configured for administering a substance to an interior of the arterial chamber from the needleless syringe and/or for withdrawing blood from the interior of the arterial chamber into the needleless syringe. Various tubing sets, hemodialysis systems, and other components, systems, and methods are also disclosed.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c. à d. hémofiltration, diafiltration
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation
• A61M 5/165 - Accessoires de filtrage, p.ex. filtres pour le sang, pour les liquides de perfusion

Abrégé

The disclosed flexible medical containers may include a substantially transparent bag including a cavity sized and configured to contain a medical substance, at least one port in fluid communication with the cavity, and at least one hanger hole sized and shaped for suspending the flexible medical container from a hanger. The hanger hole may be at least partially surrounded by a colored material to provide visible contrast between the colored material and the hanger hole. In some disclosed examples, the flexible medical containers may include one or more digit holes adjacent to the hanger hole to facilitate lifting and holding the flexible medical containers. Various other flexible medical containers, systems, and methods are also disclosed.

Classes IPC  ?

• A61J 1/10 - Récipients du type sac
• A61J 1/18 - Dispositions pour indiquer l'état, p.ex. l'état stérile, du contenu du récipient
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques - Détails; Accessoires à cet effet

Abrégé

The disclosed packaging containers may include a body including a sidewall and at least one top flap for at least partially covering an opening of the body when assembled and perforations in the sidewall of the body. The perforations may include a lower perforation having a first end portion and a second end portion; a first side perforation extending upward toward the top flap from the first end portion of the lower perforation; and a second side perforation extending upward from the second end portion of the lower perforation, wherein the first side perforation and the second side perforation converge toward each other as they extend upward from the lower perforation. Various other packaging containers, systems, and methods are also disclosed.

Classes IPC  ?

• B65D 5/54 - Lignes de moindre résistance facilitant l'ouverture des réceptacles ou leur division en parties séparées, par découpage ou déchirement
• B65B 61/18 - Dispositifs accessoires, non prévus ailleurs, opérant sur feuilles, flans, bandes, attaches, réceptacles ou paquets pour appliquer ou incorporer des éléments d'ouverture ou de déballage des paquets, p.ex. bandes de déchirure
• B65D 17/28 - Réceptacles rigides ou semi-rigides spécialement conçus pour être ouverts par coupage ou perçage, ou en perçant ou en déchirant des éléments ou des parties frangibles le long de lignes ou à partir de points de moindre résistance
• B65D 17/353 - Aménagement ou conception des pattes à tirer ou à lever caractérisés par le moyen de connexion de la patte avec un élément ou une partie détachables du réceptacle le moyen de connexion formant partie intégrante de la patte ou de l'élément ou de la partie détachables

Abrégé

An apparatus used in analyzing spent dialysate includes at least a first surface configured to accommodate a dialysate drain bag in a first predetermined position, and at least a second surface configured to accommodate a dialysate analysis device in a second predetermined position, such that when the dialysate drain bag is in the first predetermined position and the dialysate analysis device is in the second predetermined position, a light sensor of the dialysate analysis device is positioned to sense light passing through the dialysate drain bag.

Classes IPC  ?

• A61M 1/28 - Dialyse péritonéale
• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation

Abrégé

A system for monitoring percentage change in blood volume (∆BV%) during dialysis treatment includes a sensor device configured to obtain hematocrit (Hct)-related measurements based on detecting light which has passed through extracorporeal blood of a patient undergoing the dialysis treatment; one or more controllers configured to: determine Hct values based on the Hct-related measurements obtained by the sensor device; determine ∆BV% values based on the determined Hct values; and generate a GUI having a ∆BV% plot based on the determined ∆BV% values; and a display device having a display configured to display the GUI having the ∆BV% plot. Zone indicators are provided on the display to distinguish between a first zone corresponding to a first ∆BV% profile, a second zone corresponding to a second ∆BV% profile, and a third zone corresponding to a third ∆BV% profile.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang

Abrégé

A computer-implemented medical system is provided. The system includes a docking station and a mobile machine. The system is configured to perform operations comprising: receiving, by the mobile machine and from a user, a request to transport the mobile machine to a target location to perform a medical treatment; automatically navigating the mobile machine to the target location; performing, by the mobile machine, the medical treatment on a patient; determining, by the mobile machine, that the medical treatment is completed and the mobile machine is disconnected from the patient; automatically navigating the mobile machine to a stationary docking station of the medical system; and determining that the mobile machine is connected to the docking station through one or more connectors, and in response, receiving, by the mobile machine, at least one of an electrical charge, a refill of one or more supplies, a cleaning, or a drain of waste.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61B 34/30 - Robots chirurgicaux
• B60W 60/00 - Systèmes d’aide à la conduite spécialement adaptés aux véhicules routiers autonomes

Abrégé

Methods to treat anemia are provided whereby an erythropoietin stimulating agent (ESA) and an iron supplement are administered by a wearable device, based on patient parameters sensed by the wearable device. The method can involve monitoring patient parameters and dosing an ESA and an iron supplement in real-time, via the wearable device.

Classes IPC  ?

• A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
• A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
• A61B 5/021 - Mesure de la pression dans le cœur ou dans les vaisseaux sanguins
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61K 38/18 - Facteurs de croissance; Régulateurs de croissance
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• G01L 1/16 - Mesure des forces ou des contraintes, en général en utilisant les propriétés des dispositifs piézo-électriques
• A61M 37/00 - Autres appareils pour introduire des agents dans le corps; Percutanisation, c. à d. introduction de médicaments dans le corps par diffusion à travers la peau
• A61M 5/158 - Aiguilles
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale

Abrégé

Techniques for real-time intradialytic hypotension (IDH) prediction are disclosed. A system obtains historical hemodialysis treatment data that is segmented into sets of machine learning training data based on temporal proximities to IDH events and trains a machine learning model to predict IDH events based on the sets of machine learning training data.

Classes IPC  ?

• A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
• A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
• A61B 5/1455 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des capteurs optiques, p.ex. des oxymètres à photométrie spectrale
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c. à d. hémofiltration, diafiltration
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus

Abrégé

A dialysis system, such as a hemodialysis system, includes a flow chamber. The flow chamber includes: a tube section having a first end and a second end, a tube section longitudinal axis extending between the first end and the second end, the tube section having an inner wall and outer wall; and a helical flow path disposed in the inner wall of the tube section, the helical flow path extending along at least a portion of the tube section longitudinal axis.

Classes IPC  ?

• A61M 1/14 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang
• A61M 1/20 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes tubulaires

Abrégé

In one aspect, a system includes a blood treatment machine; a dialyzer configured to be coupled to the blood treatment machine, the dialyzer including a dialyzer housing defining a blood inlet and a blood outlet; a bundle of hollow fibers within an interior of the dialyzer housing; a pumping device drivable to force blood received from the blood inlet through lumens of the bundle of hollow fibers and out the blood outlet; a dialysate inlet port in fluid communication with a dialysate flow path that includes space in the interior of the dialyzer housing between the bundle of hollow fibers; and a dialysate outlet port in fluid communication with the dialysate flow path. The system further includes a fluid conditioning system configured to (i) prepare and supply fresh dialysate to the dialyzer via the dialysate inlet port, and (ii) receive spent dialysate from the dialyzer via the dialysate outlet port, recycle the spent dialysate, and supply the recycled dialysate to the dialyzer via the dialysate inlet port.

Classes IPC  ?

• A61M 1/16 - Systèmes de dialyse; Reins artificiels; Oxygénateurs du sang avec membranes
• A61M 39/22 - Soupapes ou agencement de soupapes
• A61M 1/34 - Filtration du sang à travers une membrane pour en éliminer une matière, c. à d. hémofiltration, diafiltration
• A61M 1/36 - Autre traitement du sang dans une dérivation du système circulatoire naturel, p.ex. adaptation de la température, irradiation
• B01D 63/00 - Appareils en général pour les procédés de séparation utilisant des membranes semi-perméables

Abrégé

The present invention relates to an injection port for connecting with a container, such as a medical fluid container. The injection port includes a barrel, a septum, and a cap, which are sequentially formed via a three-shot injection molding process. The present invention further relates to an assembly that includes the injection port connected to a container. Further, the present invention relates to a method of making the injection port utilizing a three-shot injection molding process.

Classes IPC  ?

• A61M 39/02 - Voies d'accès
• A61M 39/04 - Voies d'accès avec des éléments perforables auto-obturants
• A61M 39/10 - Raccords ou accouplements pour tubes
• A61M 39/20 - Couvercles ou bouchons d'obturation pour connecteurs ou extrémités ouvertes de tubes
• A61J 1/14 - Récipients spécialement adaptés à des fins médicales ou pharmaceutiques - Détails; Accessoires à cet effet