Embodiments described herein include an analyte monitoring system including an application executing on a mobile device and an analyte monitoring system server. The application is configured to detect that a communication channel between the application and the analyte monitoring system server is non-responsive and taking actions in response or recommending options to correct the non-responsive communication channel. Techniques include receiving a notification from the analyte monitoring system server via a notification service server. In response to receiving the notification, output of a first connectivity alert is canceled. Also in response to receiving the notification, output of a second connectivity alert is scheduled to be output at expiration of a timer unless the mobile device receives a second notification from the analyte monitoring system server. When output, the second connectivity alert indicates that the application has not established a connection with the analyte monitoring system server for a period of time.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
2.
INTRAVASCULAR STENT HAVING HIGH FATIGUE PERFORMANCE
This invention is directed to an expandable stent for implantation in a body lumen, such as an artery, and a method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common axis and interconnected by one or more links. A Y-shaped member is comprised of a U-shaped member and a link having a curved portion and a straight portion to improve the flexibility and thereby improve the fatigue performance of the Y-link junction.
A61F 2/915 - Stents ayant une forme caractérisée par des éléments filiformes; Stents ayant une forme caractérisée par une structure de type filet ou de type à mailles caractérisés par une structure de type filet ou de type à mailles fabriquée à partir de feuilles perforées ou de tubes perforés, p.ex. perforés par découpe au laser ou gravés avec des bandes présentant une structure en méandre, des bandes adjacentes étant reliées l’une à l’autre
A61F 2/89 - Stents ayant une forme caractérisée par des éléments filiformes; Stents ayant une forme caractérisée par une structure de type filet ou de type à mailles les éléments filiformes comprenant au moins deux anneaux adjacents reliés de manière flexible par des éléments séparés
An epicardial anchor device may include a base defining a radial slot, and a top component including a first piece and a second piece each operably coupled to the base. The first piece may include a first recess and the second piece may include a second recess. The epicardial anchor device may have (i) an unpinned condition in which the first piece and the second piece are spaced from each other a first distance so that a tether may be laterally slid within the radial slot and between the first piece and the second piece, and (ii) a pinned condition in which the first piece and the second piece are spaced from each other a second distance so that the tether may be confined within an aperture defined by the first recess and the second recess, the second distance being smaller than the first distance.
The present disclosure relates to devices, systems, and methods for improving or optimizing peripheral vision. In particular, various IOL designs, as well as IOL implantation locations, are disclosed which improve or optimize peripheral vision.
Methods and apparatus to reduce anxiety using mixed reality are disclosed herein. An example method of reducing anxiety in a person during a blood collection process includes providing a mixed reality headset to a person prior to collecting blood from the person. The method includes initiating a mixed reality program on the mixed reality headset. The mixed reality program causes a display device to display a mixed reality environment with one or more virtual objects on glasses of the headset, determines a gaze direction of the eyes of the person, and causes a change in one or more of the virtual objects in the mixed reality environment based on the gaze direction. The method further includes collecting blood from the person while the person is exposed to the mixed reality program.
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
A61B 3/113 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure objective, c. à d. instruments pour l'examen des yeux indépendamment des perceptions ou des réactions du patient pour déterminer ou enregistrer le mouvement de l'œil
A61B 5/16 - Dispositifs pour la psychotechnie; Test des temps de réaction
A61M 21/00 - Autres dispositifs ou méthodes pour amener un changement dans l'état de conscience; Dispositifs pour provoquer ou arrêter le sommeil par des moyens mécaniques, optiques ou acoustiques, p.ex. pour mettre en état d'hypnose
6.
IMPLANTABLE MEDICAL DEVICE (IMD) INCLUDING SENSING AMPLIFIER CIRCUITRY
An implantable medical device (IMD) configured to sense biosignals of a patient. The IMD comprises one or more power components for powering the IPG and sensing circuitry for sensing one or more biosignals of the patient, wherein the sensing circuitry comprises a hybrid circuit having a BJT portion and a CMOS FET portion, the BJT portion configured to amplify low voltage signals with low equivalent noise and the CMOS FET portion forming a power-optimized output stage.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
7.
CATHETER SHAFT HAVING HIGHLY RESILIENT RUBBER MEMBER AND METHOD OF MANUFACTURE
Catheter shaft assemblies that include a rubber member and a ring electrode mounted to induce radial deformation of the rubber member to inhibit loss of interference fit of the ring electrode, and related methods of fabrication, are disclosed. A catheter shaft assembly includes an elongate tubular inner layer, a first rubber member, an elongate outer layer, and one or more ring electrodes. The first rubber member is disposed on an exterior surface of the elongate tubular inner layer. The elongate outer layer covers an exterior surface of the first rubber member or the elongate tubular inner layer. The one or more ring electrodes are attached to and encircle the elongate outer layer or the first rubber member. Each of the ring electrodes induces a radial hyperelastic deformation of the first rubber member that inhibits loss of an interference fit of the ring electrode.
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
Apparatuses, systems and methods for providing improved ophthalmic lenses, particularly intraocular lenses (IOLs), include features for providing improved extended depth of focus lenses. Exemplary ophthalmic lenses can include an optic including a diffractive profile including at least one set of echelettes, each echelette of the set having a different width in r-squared space than any other echelette of the set and the at least one set of echelettes repeating at least once upon the optic.
B29D 11/00 - Fabrication d'éléments optiques, p.ex. lentilles ou prismes
G16H 20/30 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies ou des activités physiques, p.ex. la physiothérapie, l’acupression ou les exercices
9.
SYSTEMS, DEVICES, AND METHODS FOR TIME-IN-RANGE AND MEAL-RELATED ANALYTE MONITORING
Systems, devices, and methods for detecting and measuring an amount of time an individual is within a predetermined analyte range based on analyte measurements. These results and related information are presented to the individual to show the individual an analyte response associated with consumed meals or change in an analyte level within a predetermined time period after meals are consumed. These results can be organized based on a ranking system so as to allow the individual to visualize analyte responses and range impact associated with the meals. Various embodiments disclosed herein relate to methods, systems, and software applications intended to engage an individual by providing direct and timely feedback regarding the individual's meal-related analyte response.
G16H 20/17 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients administrés par perfusion ou injection
G16H 20/60 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant le contrôle de l’alimentation, p.ex. les régimes
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A pull wire assembly for a steerable medical device can include wire lock and a wire. The wire lock includes a spool body having first and ends and first and second rims respectively around the first and second ends. A through-hole extends diametrically through the spool body. The wire enters through a distal end of the through-hole, emerges through a proximal end of the through-hole, wraps around an exterior of the spool body, re-enters into the distal end of the through-hole, and re-emerges through the proximal end of the through-hole. The wire may make multiple such passes. The wire may also be tensioned to at least partially embed into the surface of the spool body.
A pull wire assembly for a steerable medical device can include wire lock and a wire. The wire lock includes a spool body having first and ends and first and second rims respectively around the first and second ends. A through-hole extends diametrically through the spool body. The wire enters through a distal end of the through-hole, emerges through a proximal end of the through-hole, wraps around an exterior of the spool body, re-enters into the distal end of the through-hole, and re-emerges through the proximal end of the through-hole. The wire may make multiple such passes. The wire may also be tensioned to at least partially embed into the surface of the spool body.
In some embodiments, a prosthetic heart valve system, includes a stent having a plurality of commissure attachment features, a cuff coupled to the stent, a plurality of leaflets, the cuff and the plurality of leaflets forming a valve assembly, and a plurality of patches, each of the plurality of patches being disposed about a selected one of the plurality of commissure attachment features and coupled thereto, the plurality of leaflets being coupled to plurality of patches.
Pulse generating circuitry configured to be coupled to a plurality of electrodes of an electroporation system is described. The pulse generating circuitry includes at least one voltage source, a plurality of output lines, switching circuitry coupled between the at least one voltage source and the plurality of output lines, each of the plurality of output lines configured to deliver at least one voltage pulse to a corresponding electrode of the plurality of electrodes, and current sensing circuitry configured to sense a current flowing through at least one of the plurality of output lines.
A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p.ex. des courants à haute fréquence
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
In some embodiments, a prosthetic heart valve system, includes a stent having a plurality of commissure attachment features, a cuff coupled to the stent, a plurality of leaflets, the cuff and the plurality of leaflets forming a valve assembly, and a plurality of patches, each of the plurality of patches being disposed about a selected one of the plurality of commissure attachment features and coupled thereto, the plurality of leaflets being coupled to plurality of patches.
A system and method for facilitating bi-directional authentication between an external device and an implanted medical device (IMD), wherein a therapy application executing on the external device is operative to communicate with the IMD via wireless telemetry communications. Certified security credentials for respective devices may be provisioned with respect to the therapy application. Upon initiating wireless telemetry communications, respective certified security credentials are mutually verified by the external device and the IMD. Responsive to successful verification, a mutual authentication process may be executed between the external device and the IMD using a respective challenge-response sequence.
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
H04L 9/30 - Clé publique, c. à d. l'algorithme de chiffrement étant impossible à inverser par ordinateur et les clés de chiffrement des utilisateurs n'exigeant pas le secret
A biostimulator, such as a leadless cardiac pacemaker, including a fixation element to engage tissue and one or more backstop elements to resist back-out from the tissue, is described. The fixation element can be mounted on a housing of the biostimulator such that a helix of the fixation element extends distally to a leading point. The leading point can be located on a distal face of the helix at a position that is proximal from a center of the distal face. The backstop elements can include non-metallic filaments, such as sutures, or can include a pinch point of the biostimulator. The backstop features can grip the tissue to prevent unscrewing of the fixation element. Other embodiments are also described and claimed.
Fabricating a capacitor includes forming conduits in a porous layer of material. The porous layer of material has particles that each includes a dielectric on a core. The formation of the conduits causes a portion of the dielectric to convert from a first phase to a second phase. The method also includes removing at least a portion of the second phase of the dielectric from the porous layer of material.
H01G 9/00 - Condensateurs électrolytiques, redresseurs électrolytiques, détecteurs électrolytiques, dispositifs de commutation électrolytiques, dispositifs électrolytiques photosensibles ou sensibles à la température; Procédés pour leur fabrication
H01G 9/045 - Electrodes caractérisées par le matériau à base d'aluminium
H01G 9/048 - Electrodes caractérisées par leur structure
H01G 9/055 - Electrodes à feuille mince gravée chimiquemennt
A pull wire assembly for a steerable medical device can include wire lock and a wire. The wire lock includes a spool body having first and ends and first and second rims respectively around the first and second ends. A through-hole extends diametrically through the spool body. The wire enters through a distal end of the through-hole, emerges through a proximal end of the through-hole, wraps around an exterior of the spool body, re-enters into the distal end of the through-hole, and re-emerges through the proximal end of the through-hole. The wire may make multiple such passes. The wire may also be tensioned to at least partially embed into the surface of the spool body.
Generally, methods of analyte monitoring management, and articles of manufacturing related thereto, are provided. The methods include receiving analyte measurement data and analyzing the analyte measurement data for health related parameters. Recommendations are determined for creating or modifying a treatment program based on the analysis, and provided within a user-interface that enables a user to create or modify the treatment program. Further, generally, methods of for managing analyte measurement data, and articles of manufacturing related thereto, are provided. The methods include receiving analyte measurement data that represent data collected over a time period, and analyzing the analyte measurement data for analyte episodes within that time period. Threshold based episodes and/or rate-of-change based episodes may be determined.
The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A pull wire assembly for a steerable medical device can include wire lock and a wire. The wire lock includes a spool body having first and ends and first and second rims respectively around the first and second ends. A through-hole extends diametrically through the spool body. The wire enters through a distal end of the through-hole, emerges through a proximal end of the through-hole, wraps around an exterior of the spool body, re-enters into the distal end of the through-hole, and re-emerges through the proximal end of the through-hole. The wire may make multiple such passes. The wire may also be tensioned to at least partially embed into the surface of the spool body.
Described herein are methods, devices, and systems that use electrogram (EGM) or electrocardiogram (ECG) data for sleep apnea detection. An apparatus and method detect potential apnea events (an apnea or hypopnea event) using a signal indicative of cardiac electrical activity of a patient's heart, such as an EGM or ECG. Described herein are also methods, devices, and systems for classifying a patient as being asleep or awake, which can be used to selectively enable and disable sleep apnea detection monitoring, as well as in other manners.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/366 - Détection de complexes QRS anormaux, p.ex. élargissement
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
23.
IMPLANTABLE MEDICAL SYSTEMS AND METHODS USED TO DETECT, CHARACTERIZE OR AVOID ATRIAL OVERSENSING WITHIN AN IEGM
Certain embodiments of the present technology described herein relate to detecting atrial oversensing, characterizing atrial oversensing, determining when atrial oversensing is likely to occur, and or reducing the chance of atrial oversensing occurring. Some such embodiments characterize and/or avoid atrial oversensing.
A61B 5/283 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électrocardiographie [ECG] invasives
A61B 5/33 - Modalités électriques se rapportant au cœur, p.ex. électrocardiographie [ECG] spécialement adaptées à l’utilisation conjointe avec d’autres dispositifs
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/368 - Stimulateurs cardiaques commandés par un paramètre physiologique, p.ex. par le potentiel cardiaque comprenant plus d'une électrode coopérant avec différentes régions du cœur
A medical device including a removable frame and biomaterial cover, methods of assembling and using the same, and a delivery system including the same are described herein. The medical device includes a frame having proximal and distal ends, the frame including a proximal disc at the proximal end, a distal disc at the distal end, and a connecting segment connecting the proximal and distal discs. Each of the proximal and distal discs includes a respective plurality of prongs, the plurality of prongs each extending from the connecting segment to a free end. The medical device further includes at least one biomaterial cover including an outer section and an inner section defining a cavity therebetween, wherein at least one of the proximal and distal discs of the frame is positioned in the cavity.
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets
A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p.ex. les vaisseaux sanguins ou le cordon ombilical
25.
METHODS OF DIAGNOSING OR AIDING IN DIAGNOSIS OF BRAIN INJURY CAUSED BY ACOUSTIC ENERGY, ELECTROMAGNETIC ENERGY, AN OVER PRESSURIZATION WAVE, AND/OR BLAST WIND
Disclosed herein are methods of aiding in the diagnosis and evaluation of a subject (e.g., a human subject) that has sustained or may have sustained an injury to the head, such as mild, moderate, severe, or moderate to severe traumatic brain injury (TBI) by detecting levels of a biomarker, such as ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) glial fibrillary acidic protein (GFAP), or a combination thereof, in samples taken from a subject (e.g., a human subject) that has or may have sustained an injury or suspected injury to the head that is caused or believed to have been caused by acoustic energy, electromagnetic energy (e.g., from a sonic weapon, a directed energy weapon or a combination thereof), an over pressurization wave, blast wind, or any combination thereof.
G01N 33/573 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour enzymes ou isoenzymes
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
26.
HBV DIAGNOSTIC, PROGNOSTIC, AND THERAPEUTIC METHODS AND PRODUCTS
Provided herein are compositions, systems, and methods for assessing and monitoring disease stage and phases, predicting likelihood of disease progression, and predicting and monitoring responses to hepatitis B virus infection.
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
27.
SEQUENCE CONVERSION AND SIGNAL AMPLIFIER DNA HAVING ABASIC NUCLEIC ACIDS, AND DETECTION METHODS USING SAME
Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting the sample, in the presence of a polymerase and an endonuclease, with a first oligonucleotide that includes, in the 5′ to 3′ direction, a signal DNA generation sequence, an endonuclease recognition site, and a complementary sequence that has at least one abasic moiety and wherein the complementary sequence has a first complementary sequence that is complementary to at least a portion of the signal DNA generation sequence and a second complementary sequence that is complementary to the 3′ end of the target nucleic acid. Also disclosed are methods that include a second oligonucleotide including, in the 5′ to 3′ direction, a second signal DNA generation sequence, an endonuclease recognition site, and a sequence that is homologous to the first signal DNA generation sequence of the first oligonucleotide and that optionally has at least one abasic site. Also disclosed chemically modified oligonucleotides, as well as compositions and kits that include the chemically modified oligonucleotides for detecting a target nucleic acid.
Apparatuses, systems and methods for providing improved ophthalmic lenses, particularly intraocular lenses (IOLs), include features for vertex matching distance regions of such lenses. Exemplary ophthalmic lenses can include an optic disposed about an optical axis and having a refractive profile including a region having an add power and a first distance region and a second distance region extending outward from the first distance region and being vertex matched with the first distance region.
Disclosed herein are implantable medical devices and systems, and methods for used therewith, that selectively perform atrial overdrive pacing while an intrinsic atrial rate of a patient is within a specified range.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/29 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électrocardiographie [ECG] invasives pour implantation permanente ou à long terme
A61B 5/364 - Détection d'intervalle ECG anormal, p.ex. des extrasystoles ou des battements cardiaques ectopiques
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p.ex. par le potentiel cardiaque
A61N 1/368 - Stimulateurs cardiaques commandés par un paramètre physiologique, p.ex. par le potentiel cardiaque comprenant plus d'une électrode coopérant avec différentes régions du cœur
30.
ASSEMBLY AND METHOD FOR THE CLOSURE OF VASCULAR ABNORMALITIES
Described herein is a patch delivery assembly for treating a target site and a method for deploying the same. The patch delivery assembly includes a patch installation frame having a self-expanding body extending between a proximal end and an open distal end and defining a lumen therethrough. The patch delivery assembly also includes a delivery cable having a distal end coupled to the proximal end of the patch installation frame and further defining the lumen, and a securement device extending through the lumen defined through the delivery cable and the patch installation frame, the securement device terminating in a distal working end including a securement mechanism. In a deployment configuration of the patch delivery assembly, the patch delivery assembly further includes a patch releasably coupled to the distal end of the patch installation frame, for securement to tissue of the target site using the securement mechanism.
A display system configured to communicate tissue proximity data from a plurality of electrodes includes a display. The display outputs a circular graphical representation. The circular graphical representation includes a plurality of color areas forming a first circular shape. Each of the color areas communicate a categorized value for a respective electrode indicative of tissue proximity for the respective electrode. A plurality of graph areas form a second circular shape. Each of the graph areas communicate a relative value for the respective electrode indicative of the tissue proximity for the respective electrode.
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
A61B 34/00 - Chirurgie assistée par ordinateur; Manipulateurs ou robots spécialement adaptés à l’utilisation en chirurgie
32.
Method and system for detecting contact status using electrode
A method of determining contact status of electrodes includes applying drive signals between pairs of electrodes, measuring a bipolar electrode complex impedance (BECI) value generated in response to the drive signals over a collection period, and determining a baseline BECI value representing a minimum value measured during the collection period. The method further includes determining contact status of the electrode by applying drive signals between pairs of electrodes over a given interval, measuring a BECI value generated in response to the drive signals, measuring a peak-to-peak value associated with the BECI values measured over the given interval, and determining contact status based on a combination of the baseline BECI value, the measured BECI value, and the peak-to-peak value associated with the measured BECI values.
A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p.ex. des courants à haute fréquence
A61B 5/053 - Mesure de l'impédance ou de la conductivité électrique d'une partie du corps
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
In one embodiment, a method for operating a system for management of implantable medical devices (IMDs), comprises: conducting communications sessions with a plurality of clinician programmer devices, wherein some of the communication sessions occur while the plurality of clinician programmer devices are engaged in respective programming sessions with IMDs; conducting communications sessions with a plurality of patient controller devices, wherein the communication sessions with the patient controller devices include communication of data pertaining to offline programming of IMDs; reconciling programming session data received from the plurality of clinician programmer devices with programming session data received from patient controller devices to identify instances of unauthorized IMD programming; and distributing revocation data to patient controller devices to be downloaded to corresponding IMDs, wherein the revocation data identifies cryptographic keys that are no longer trusted.
A method of quantifying the effect of peripheral optical errors on driving includes displaying, on a central portion of a display, a visual representation of a vehicle on a dynamic roadway; intermittently displaying a curve in the dynamic roadway; intermittently displaying, on a peripheral portion of the display, a target object; receiving a signal in response to a participant viewing the target object; determining a reaction time and determining target detection accuracy. Another method includes displaying a participant 10 vehicle and a lead vehicle in front of the participant vehicle on a roadway; signaling an alert when the participant vehicle is outside of a distance range to the lead vehicle; intermittently displaying, on a peripheral portion of the display, a target object; receiving a signal in response to a participant detecting the target; and quantifying the effect of the peripheral optical errors based on reaction time and target detection accuracy.
Systems and methods for an implantable medical device which utilizes a patch antenna for communicating with an external device. The implantable medical device includes a housing, a header, and a patch antenna formed using an RF plate and a ground plate, which may be or include a metal surface of the housing. Also, a material of the header forms a dielectric of the patch antenna.
Disclosed herein are methods for aiding in the diagnosis and evaluation of a subject (e.g., a human subject) that has sustained or may have sustained an injury to the head, such as to determine whether the subject is suffering from a mild or a supermild traumatic brain injury.
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
40.
HIGH DENSITY PADDLE CATHETER WITH DISTAL COUPLER AND DISTAL ELECTRODE
A catheter (e.g., high-density mapping catheter) and related catheter system is described herein. The catheter includes an elongated catheter shaft, and an electrode assembly. The electrode assembly includes a first spline assembly, a second spline assembly, and a distal coupler assembly. Each of the spline assembly includes a distal portion and spline assembly electrodes distributed along the spline assembly. The distal coupler assembly includes a base member and a distal electrode. The base member defines an opening configured to receive and accommodate the distal portion of the second spline assembly. The distal electrode is configured to be mounted to the base member to secure the distal portion of the second spline assembly within the opening. The distal electrode can be configured for cardiac mapping, tissue ablation, and/or bipolar pacing.
Methods and systems for providing therapy related data management are provided. The subject systems include one or more device components, and at least one memory storage unit and at least one data storage unit associated with such one or more device components. The device components may include one or more of an analyte monitoring system, a fluid delivery device and a remote terminal. The subject methods include use of the subject systems to optimize treatment of a patient.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
G16H 20/17 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients administrés par perfusion ou injection
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
42.
SYSTEM AND METHOD FOR DETERMINING THE IMPACT OF PERIPHERAL OPTICAL ERRORS ON PATIENT LOCOMOTION
A method of quantifying the effect of peripheral optical errors on patient locomotion includes projecting a pattern on the floor that includes a discrete shapes and empty spaces between the discrete shapes. The method also includes tracking a position of the participant along the pattern as the participant traverses the pattern, and determining foot placement accuracy, utilizing a optical motion capture system and a computer, as the participant walked through the pattern by determining a total area of overlap between the participant's feet and the empty spaces of the pattern. In another embodiment, the method includes arranging obstacles in front of a participant, intermittently displaying a character in front of the participant, determining participant's accuracy in identifying or counting the characters, and determining the participant's step length and foot clearance as the participant steps over the obstacles to quantify the effect of the peripheral optical errors on the participant's locomotion.
A display system configured to communicate tissue proximity data from a plurality of electrodes includes a display. The display outputs a circular graphical representation. The circular graphical representation includes a plurality of color areas forming a first circular shape. Each of the color areas communicate a categorized value for a respective electrode indicative of tissue proximity for the respective electrode. A plurality of graph areas form a second circular shape. Each of the graph areas communicate a relative value for the respective electrode indicative of the tissue proximity for the respective electrode.
Various embodiments of the present disclosure provide a medical device straightener. The medical device straightener can comprise an elongate shaft extending along a shaft longitudinal axis, the elongate shaft including a shaft proximal end and a shaft distal end, wherein a shaft inner wall of the elongate shaft defines a shaft lumen extending therethrough. The medical device straightener can comprise a bleedback valve that includes an outer circumferential surface. The bleedback valve can be disposed at a distal end of the elongate shaft, within the shaft lumen, wherein a portion of the outer circumferential surface is in communication with the shaft inner wall. The bleedback valve can define a radially expandable lumen longitudinally extending through a center of the bleedback valve.
St. Jude Medical International Holding S.a r.l. (Luxembourg)
Inventeur(s)
Hill, Anthony D.
Hauck, John
Albu, Ryan M.
Curran, Timothy G.
Link, Ryan
Abrégé
A transmitting element for generating a magnetic field for tracking of an object includes a first spiral trace that extends from a first outer origin inward to a central origin in a first direction. A second spiral trace can extend from the central origin outward to a second outer origin in the first direction. The second spiral trace can extend from the central origin to the second outer origin in the first direction. The first spiral trace and the second spiral trace can be physically connected at the central origin to form the fluorolucent magnetic transmitting element and at least a portion of the first spiral trace overlaps at least a portion of the second spiral trace.
A method of quantifying the effect of peripheral optical errors on patient locomotion includes projecting a pattern (102) on a floor (103), wherein the pattern (102) includes discrete shapes, such as squares (112), separated empty spaces (113). The method also includes tracking a position of the participant along the pattern (102) as the participant traverses the pattern (102), and determining foot placement accuracy, utilizing a optical motion capture system and a computer, as the participant walked through the pattern (102) by determining a total area of overlap between the participant's feet and the empty spaces (113) of the pattern (102). In another embodiment, the method includes arranging obstacles (301, 302) in front of a participant (306), intermittently displaying a character in front of the participant, determining the participant's accuracy in identifying or counting characters on a display (307), and determining using a optical motion capture system (305) the participant's step length and foot clearance as the participant steps over the obstacles (301, 302) to quantify the effect of the peripheral optical errors on the participant's locomotion.
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 3/024 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux du type à mesure subjective, c. à d. appareils de d’examen nécessitant la participation active du patient pour la détermination du champ de vision, p.ex. périmètres
47.
DRIVING SIMULATOR TESTING FOR DETERMINING THE FUNCTIONAL IMPACT OF PERIPHERAL OPTICAL ERRORS
A method of quantifying the effect of peripheral optical errors on driving includes displaying, on a central portion of a display, a visual representation of a vehicle on a dynamic roadway; intermittently displaying a curve in the dynamic roadway; intermittently displaying, on a peripheral portion of the display, a target object; receiving a signal in response to a participant viewing the target object; determining a reaction time and determining target detection accuracy. Another method includes displaying a participant vehicle and a lead vehicle in front of the participant vehicle on a roadway; signaling an alert when the participant vehicle is outside of a distance range to the lead vehicle; intermittently displaying, on a peripheral portion of the display, a target object; receiving a signal in response to a participant detecting the target; and quantifying the effect of the peripheral optical errors based on reaction time and target detection accuracy.
G09B 9/052 - Simulateurs pour l'enseignement ou l'entraînement pour l'enseignement de la conduite des véhicules ou autres moyens de transport pour l'enseignement de la conduite des véhicules terrestres caractérisés par des moyens pour enregistrer ou mesurer les performances de l'élève
G09B 9/05 - Simulateurs pour l'enseignement ou l'entraînement pour l'enseignement de la conduite des véhicules ou autres moyens de transport pour l'enseignement de la conduite des véhicules terrestres la vue à partir d'un véhicule étant simulée
48.
METHOD AND SYSTEM TO DETECT P-WAVES IN CARDIAC ARRHYTHMIC PATTERNS
A computer implemented method for detecting arrhythmias in cardiac activity including obtaining far field cardiac activity (CA) signals for a series of beats. For at least a portion of the beats, the one or more processors perform, on a beat by beat basis: a) identifying first and second feature of interests (FOI) from a segment of the CA signal that corresponds to a current beat; and b) classifying the current beat into one of first and second groups. The method also includes designating one of the first and second groups to be a primary group based on a relation between the first and second groups, and for the beats in the primary group, selecting one of the first and second FOIs as the R-wave FOI. The method also includes rejecting an arrhythmia detection based on the P-waves detected.
A catheter (e.g., high-density mapping catheter) and related catheter system is described herein. The catheter includes an elongated catheter shaft, and an electrode assembly. The electrode assembly includes a first spline assembly, a second spline assembly, and a distal coupler assembly. Each of the spline assembly includes a distal portion and spline assembly electrodes distributed along the spline assembly. The distal coupler assembly includes a base member and a distal electrode. The base member defines an opening configured to receive and accommodate the distal portion of the second spline assembly. The distal electrode is configured to be mounted to the base member to secure the distal portion of the second spline assembly within the opening. The distal electrode can be configured for cardiac mapping, tissue ablation, and/or bipolar pacing.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/287 - Supports pour électrodes multiples, p.ex. cathéters à électrode pour des études électrophysiologiques [EEP]
A61B 5/367 - Modalités électriques se rapportant au cœur, p.ex. électrocardiographie [ECG] Études électrophysiologiques [EEP], p.ex. cartographie de l’activation électrique ou cartographie électroanatomique
Systems, devices, and methods for a dual analyte sensor using glucose history from a glucose sensor in combination with data from a ketone sensor to control operation of a user interface device or insulin pump are provided. In some embodiments, the systems, apparatus or methods may make use of combination of glucose history and a β-hydroxybutyrate physiological model to better predict diabetic ketoacidosis (DKA), in comparison to a prediction based on a simple high glucose threshold. In other embodiments, the systems, apparatus or method may include features for generating an estimate of the patient's medication state and/or knowledge of medication information, such as a patient with T1 diabetes mellitus (DM) using an SGLT-2 inhibitor.
A nutritional composition for use in enhancing one or more features or functions of the blood-brain barrier, including promoting healing or improved function of the blood-brain barrier. In certain embodiments, a method comprises administering to an individual in need thereof a nutritional composition comprises at least one human milk oligosaccharide as described herein to treat or prevent one or more blood-brain barrier related conditions.
A23L 33/21 - Adjonction de substances essentiellement non digestibles, p.ex. de fibres diététiques
A23L 33/00 - Modification de la qualité nutritive des aliments; Produits diététiques; Leur préparation ou leur traitement
A61K 31/702 - Oligosaccharides, c. à. d. ayant trois à cinq radicaux saccharide liés les uns aux autres par des liaisons glycosidiques
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A prosthetic heart valve includes a support structure and a valve assembly disposed within the support structure, the valve assembly including a plurality of leaflets. Each leaflet is formed from a predetermined leaflet material. Some leaflet materials include a metal body with a plurality of openings. The metal body may be coated with a polymer. Other leaflet materials include natural mammalian tissue subjected to a plastination preservation process.
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Dietetic food and substances adapted for medical use; dietary supplements for humans; nutritive preparations and supplements, namely, nutritionally fortified beverages and powders for human consumption for medical purposes; dietetic foods adapted for medical use, namely, liquid nutritive preparations for tube feeding; nutritional and dietary supplements, namely, electrolyte solutions; nutritionally fortified beverages and powders for meal replacement for medical purposes; milk-based infant formula; pediatric nutritive preparations for human use; liquid nutritive supplements for human use; nutritionally fortified beverages and powders for meal replacement; nutritionally fortified supplements in the form of powder beverages; nutritional and dietary supplements, namely, electrolyte replacement solutions
09 - Appareils et instruments scientifiques et électriques
Produits et services
Downloadable software for sharing, reporting, maintaining, managing, monitoring, and analyzing medical data; mobile applications for sharing, reporting, maintaining, managing, monitoring, and analyzing medical data; software in the fields of health, wellness, disease management, and medical diagnostics; mobile applications in the fields of health, wellness, disease management, and medical diagnostics; medical software; medical mobile applications; downloadable software for use by patients, their families, and health care professionals enabling users to track and share therapy progress and healthcare information in the areas of chronic pain and movement disorders management; computer application software for use with mobile devices in the nature of tablet computers, PDAs and cell phones, namely, software for accessing patient's medical device data and transmitting information in the nature of medical and physiological data between the medical device and health clinics
29 - Viande, produits laitiers et aliments préparés ou conservés
Produits et services
Milk; milk products excluding ice cream, ice milk and frozen yogurt; ready to drink dairy based protein food beverages; dairy-based powders for making dairy-based food beverages and shakes
Fruit-based beverages; vegetable juices and smoothies; fruit juices and smoothies; powders used in the preparation of fruit-based beverages and vegetable-based beverages; non-alcoholic fruit-flavored beverages; drinking water containing electrolytes; sports drinks containing electrolytes; sport drinks, namely, performance drinks
Medical diagnostic instruments for diabetes diagnosis and monitoring; medical diagnostic instruments for analyzing, measuring and testing blood, bodily fluids and/or tissue; medical diagnostic instruments for in vitro diagnostic testing and/or analysis; medical diagnostic instruments for microbial screening and identification, analysis of nucleic acid sequences, nucleic acids, genetic materials, infectious agents and/or pathogens; medical and surgical apparatus and instruments, namely, stents, catheters, guide wires, bioabsorbable stents, drug-eluting stents, scaffolding for catheters and stents for use in vascular procedures; medical apparatus and equipment, namely, patient monitor that is for use in electronic acquisition, capture and transmission of medical device status and patient medical and physiological data used in connection with implantable cardiac devices, and external or implantable cardiac therapeutic or diagnostic devices; medical diagnostic instruments for testing patients for respiratory, community acquired, hospital acquired, sexual health, gastro-enteric, vector borne, blood borne pathogen, and tropical disease infections; medical diagnostic apparatus and incorporated recorded computer software for analyzing medical data and informing treatment decisions, all sold as a unit, for medical diagnostic use; medical apparatus and instruments; medical diagnostic test kits; wellness test kits; health test kits; medical testing kits; blood, bodily fluid, tissue, and fecal matter testing instruments; specimen collection devices; specimen collection kits; medical apparatus for monitoring, tracking, and determining analyte concentrations; sensors for monitoring, tracking, and determining analyte concentrations for health purposes; medical apparatus and instruments for diabetes management use; medical apparatus and instruments for monitoring glucose; medical apparatus and instruments for monitoring ketones; instruments and apparatus for monitoring glucose for health purposes; instruments and apparatus for monitoring ketones for health purposes; patient monitoring sensors for monitoring glucose concentrations; patient monitoring sensors for monitoring ketone concentrations; sensor-based glucose monitors for medical purposes; sensor-based ketone monitors for medical purposes; analyte monitoring systems for monitoring glucose; analyte monitoring systems for monitoring ketones; medical devices, namely, catheters and catheter interface modules; medical and surgical catheters; enteral nutritional delivery system; breastmilk storage bottle; infant formula storage bottle; baby bottles; baby nursers
58.
METHOD AND DEVICE FOR DETECTING ABNORMAL BATTERY CONSUMPTION DUE TO EXTRA-BATTERY MECHANISMS
Systems, methods, and devices are provided for determining an early battery depletion (EBD) condition of an implantable medical device that includes a memory storing program instructions and a processor executing the program instructions. Circuitry is electrically coupled to the processor, and the circuitry and processor perform one or more tasks related to at least one of collecting signals indictive of physiologic activity, analyzing collected signals, delivering therapy, or communicating with an external device. A battery supplies energy to the circuitry and processor. A monitoring circuit coupled to the battery measures actual energy usage from the battery representing at least one of a current draw from the battery during corresponding tasks or a voltage measurement across the battery. Circuitry and processor calculate projected energy usage from the battery in connection with the corresponding tasks, and determine when an EBD condition exists based on projected energy usage and actual energy usage.
G01R 31/392 - Détermination du vieillissement ou de la dégradation de la batterie, p.ex. état de santé
G01R 31/367 - Logiciels à cet effet, p.ex. pour le test des batteries en utilisant une modélisation ou des tables de correspondance
G01R 31/3835 - Dispositions pour la surveillance de variables des batteries ou des accumulateurs, p.ex. état de charge ne faisant intervenir que des mesures de tension
Improved graphical user interfaces for analyte monitoring systems are provided. For example, disclosed herein are various embodiments of GUIs, each of which include a graph portion comprising a trend line indicative of a user's analyte levels over a predetermined time period, and a plurality of summary metrics comprising a plurality of minimum analyte levels and maximum analyte levels associated with a plurality of time increments within the predetermined time period. In many embodiments, the plurality of minimum analyte levels and maximum analyte levels are aligned with an x-axis of the graph portion.
Disclosed herein are methods for aiding in the diagnosis and evaluation of a subject (e.g., a human subject) that has sustained or may have sustained an injury to the head, such as to determine whether the subject is suffering from a mild or a supermild traumatic brain injury.
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
Systems, devices and methods are provided for incorporating a medication delivery device into an integrated management system. The integrated management system may be an integrated diabetes management system and may include a glucose monitor, a connected insulin pen, and software. The integrated management system may produce a plurality of reports that may include data related to analyte levels (e.g., glucose levels) and medication delivered (e.g., insulin delivered). The integrated system may also include a mode in which certain types of data are no longer shared and/or stored if the user is not signed into an account. The types of data shared and/or stored when the user is not signed into an account may differ from the types of data shared and/or stored when the user is signed into an account.
G06F 11/07 - Réaction à l'apparition d'un défaut, p.ex. tolérance de certains défauts
G16H 20/17 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients administrés par perfusion ou injection
H04W 4/80 - Services utilisant la communication de courte portée, p.ex. la communication en champ proche, l'identification par radiofréquence ou la communication à faible consommation d’énergie
G06F 9/451 - Dispositions d’exécution pour interfaces utilisateur
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G16H 15/00 - TIC spécialement adaptées aux rapports médicaux, p.ex. leur création ou leur transmission
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
09 - Appareils et instruments scientifiques et électriques
Produits et services
Downloadable software for diabetes management; downloadable software for health data management in the field of diabetes management; health software for use in connection with diabetes management; diabetes management software for receiving, storing, displaying, tracking, sharing, reporting, maintaining, managing, monitoring, and analyzing health data and information; software for receiving, storing, displaying, tracking, sharing, reporting, maintaining, managing, monitoring, and analyzing analyte data; diabetes management software for facilitating communication and collaboration between clinicians, caregivers, and patients; downloadable software for enabling users to receive personalized recommendations related to diabetes management; downloadable software for providing education in the field of diabetes management; downloadable software to facilitate social networking in the field of diabetes management; downloadable software to facilitate support and sharing of information in the field of diabetes management; downloadable electronic newsletters delivered by e-mail in the field of diabetes management.
63.
Liquid Nutritional Compositions with Water-Insoluble Plant Flavonoid and Method of Production Thereof
A method of forming a heat-treated liquid nutritional composition having a neutral pH and comprising a water-insoluble plant flavonoid comprises providing an aqueous liquid nutritional composition having a pH of from about 6 to about 7.5 and comprising protein, fat, carbohydrate, and water-insoluble plant flavonoid, homogenizing the liquid nutritional composition at a pressure of at least about 2000 psi, and heat treating the liquid nutritional composition. A heat-treated liquid nutritional composition having a pH of from about 6 to about 7.5 comprises a water-insoluble plant flavonoid, protein, fat and carbohydrate. At least about 75 wt % of the water-insoluble plant flavonoid remains suspended throughout the liquid nutritional composition after two months of storage at room temperature.
Disclosed herein are methods of determining whether a subject has a traumatic brain injury (TBI) by detecting levels of at least one biomarker, such as ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) glial fibrillary acidic protein (GFAP), or a combination thereof, in samples taken from a subject.
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
Embodiments described herein include methods and/or systems for updating a medical device. Embodiments include medical devices which are configured for updates in response to various events including connection of a peripheral device to the medical device, a user initiated event, or based on received recommendations.
G01N 33/487 - Analyse physique de matériau biologique de matériau biologique liquide
G06F 11/14 - Détection ou correction d'erreur dans les données par redondance dans les opérations, p.ex. en utilisant différentes séquences d'opérations aboutissant au même résultat
66.
CONNECTORS FOR MAKING CONNECTIONS BETWEEN ANALYTE SENSORS AND OTHER DEVICES
Glucose monitoring devices and related systems and methods, the glucose monitoring devices including a sensor electronics unit having a housing and a printed circuit board disposed within the housing, a transcutaneous glucose sensor assembly, and a conductive sensor connector. The printed circuit board includes a first electrical contact, the transcutaneous glucose sensor assembly includes a distal portion having a working electrode and proximal portion having a working-electrode contact in electrical communication with the working electrode, and the conductive sensor connector electrically connects the working-electrode contact with the first electrical contact. Further, the conductive sensor connector extends through a hole in the proximal portion of the transcutaneous glucose sensor assembly and through a hole in the printed circuit board.
A61B 5/1486 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des électrodes enzymatiques, p.ex. avec oxydase immobilisée
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/1468 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p.ex. par des moyens polarographiques
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p.ex. par des moyens polarographiques invasifs, p.ex. introduits dans le corps par un cathéter
H05K 3/32 - Connexions électriques des composants électriques ou des fils à des circuits imprimés
67.
STIMULATION LEAD AND METHOD INCLUDING A MULTI-DIMENSIONAL ELECTRODE ARRAY
Stimulation lead includes an elongated lead body having distal and proximal ends and wire conductors extending therebetween. The stimulation lead also includes a lead paddle having a multi-dimensional array of electrodes positioned along a contact side of the lead paddle. The electrodes are electrically coupled to the wire conductors. The lead paddle includes a paddle body and a conductor organizer disposed within the paddle body. The conductor organizer has multiple channels extending along the lead paddle. The channels receive the wire conductors and retain the wire conductors in a designated arrangement with respect to the lead paddle. The conductor organizer has openings to the channels. The wire conductors extend through the openings and are terminated to the respective electrodes.
A method and device for managing establishment of a communications link between an external instrument (EI) and an implantable medical device (IMD) are provided. The method stores, in a memory in at least one of the IMD or the EI, a base scanning schedule that defines a pattern for scanning windows over a scanning state. The method enters the scanning state during which a receiver scans for advertisement notices during the scanning windows. At least a portion of the scanning windows are grouped in a first segment of the scanning state. The method stores, in the memory, a scan reset pattern for restarting the scanning state. Further, the method automatically restarts the scanning state based on the scan reset pattern to form a pseudo-scanning schedule that differs from the base scanning schedule and establishes a communication session between the IMD and the EI.
A prosthetic heart valve may include a collapsible and expandable frame that, in an expanded condition, includes a central portion, an atrial portion flaring radially outwardly from the central portion, and a ventricular portion flaring radially outwardly from the central portion. A tube positioned within the frame may have a lumen extending along a longitudinal axis of the frame, wherein the tube is formed of tissue or fabric. Prosthetic leaflets may be directly coupled to the tube to form a valve allowing blood to flow through the lumen of the tube in an antegrade direction but substantially blocking blood from flowing through the lumen of the tube in a retrograde direction. A plurality of cords may each have a first end coupled to the frame and a second end coupled to the tube. Each of the plurality of cords may extend in a radial direction toward the longitudinal axis.
Aspects of the present disclosure are directed to, for example, a high-thermal-sensitivity ablation catheter tip including a thermally-insulative ablation tip insert supporting at least one temperature sensor electrically coupled to a flexible electronic circuit and encapsulated, or essentially encapsulated, by a conductive shell. Also disclosed is a method of controlling the temperature of an ablation catheter tip while creating a desired lesion using various forms of energy and energy delivery.
A61B 18/18 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par application de radiations électromagnétiques, p.ex. de micro-ondes
71.
HBV DIAGNOSTIC, PROGNOSTIC, AND THERAPEUTIC METHODS AND PRODUCTS
Provided herein are compositions, systems, and methods for assessing and monitoring disease stage and phases, predicting likelihood of disease progression, and predicting and monitoring responses to hepatitis B virus infection.
Systems, devices, and methods for a dual analyte sensor using glucose history from a glucose sensor in combination with data from a ketone sensor to control operation of a user interface device or insulin pump are provided. In some embodiments, the systems, apparatus or methods may make use of combination of glucose history and a β-hydroxybutyrate physiological model to better predict diabetic ketoacidosis (DKA), in comparison to a prediction based on a simple high glucose threshold. In other embodiments, the systems, apparatus or method may include features for generating an estimate of the patient's medication state and/or knowledge of medication information, such as a patient with T1 diabetes mellitus (DM) using an SGLT-2 inhibitor.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/1486 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des électrodes enzymatiques, p.ex. avec oxydase immobilisée
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
Improved graphical user interfaces for analyte monitoring systems are provided. For example, disclosed herein are various embodiments of GUIs, each of which include a graph portion comprising a trend line indicative of a user's analyte levels over a predetermined time period, and a plurality of summary metrics comprising a plurality of minimum analyte levels and maximum analyte levels associated with a plurality of time increments within the predetermined time period. In many embodiments, the plurality of minimum analyte levels and maximum analyte levels are aligned with an x-axis of the graph portion.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
Medical apparatus and instruments for diabetes management use; medical apparatus and instruments for monitoring glucose; medical apparatus and instruments for monitoring ketones; sensor-based glucose monitors; sensor-based ketone monitors; glucose and ketone monitoring systems; continuous glucose monitoring systems; continuous ketone monitoring systems; medical apparatus for determination of analyte concentrations for diabetes management purposes; medical apparatus for monitoring analyte concentrations for diabetes management purposes; patient monitoring sensors for diabetes management; diabetes management monitoring devices; sensors for diabetes management.
75.
System and method for providing transcutaneous or subcutaneous temporal interference spinal cord stimulation
A noninvasive/minimally invasive neuromodulation system and method for providing therapy to a target neural tissue of a patient. In one arrangement, an example method comprises applying at least two input waveforms to respective pairs of electrodes affixed on the patient's skin or subcutaneously disposed relative to the target neural tissue, wherein the frequencies of the input waveforms are configured such that they combine, when simultaneously applied, to generate a beat waveform having a beat frequency due to interference. The beat waveform is causative of a transcutaneous/subcutaneous temporal interference (T/STI) electric field generated in the patient body, the T/STI electric field including an interference region at least partially overlapping the target neural tissue of the patient, wherein the beat frequency is of a value operative to impart a therapeutic effect to the target neural tissue.
A61N 1/06 - Electrodes pour traitement à haute fréquence
A61N 1/32 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
76.
Method and system for determining baseline electrode impedance for tissue contact detection
A method of determining a baseline impedance value for a first electrode in a plurality of electrodes located on a medical device for tissue contact detection includes measuring an impedance value of the first electrode generated in response to a drive signal to the first electrode. The method further includes assigning a baseline impedance value to the first electrode based on impedance values measured in a predetermined time interval and determining a confidence value associated with the baseline impedance value. The method further includes utilizing the baseline impedance value in determining contact status of the first electrode when the confidence value is at or above a predetermined threshold value.
A61B 5/053 - Mesure de l'impédance ou de la conductivité électrique d'une partie du corps
A61B 18/12 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci par chauffage en faisant passer des courants à travers les tissus à chauffer, p.ex. des courants à haute fréquence
A61B 18/00 - Instruments, dispositifs ou procédés chirurgicaux pour transférer des formes non mécaniques d'énergie vers le corps ou à partir de celui-ci
77.
NEUROSTIMULATION METHOD AND SYSTEM FOR MANAGING A DISCHARGE PROFILE IN PRESENCE OF MRI/EMI INTERFERENCE
A neurostimulation (NS) system and method are provided. The NS system includes an array of electrodes positioned within a patient. The array of electrodes includes an active electrode. The active electrode is configured to be a cathode electrode located proximate to neural tissue of interest that is associated with a target region. The NS system includes an anode electrode and an electromagnetic interference (EMI) antenna. A control circuit is configured to control delivery of a NS therapy during a therapy delivery interval. The NS therapy is to be delivered between the anode electrode and the active electrode. The NS system develops a residual voltage between the anode electrode and the active electrode over the therapy delivery interval. A current regulator (CR) circuit is connected to the cathode electrode. The CR circuit is configured to control current flow through the cathode electrodes. During a discharge operation, the control circuit is configured to manage the CR circuit to control a discharge current flow over the discharge operation to discharge the residual voltage after therapy delivery in a manner that follows an actively emulated passive discharge (AEPD) profile. During the discharge operation, the CR circuit is connected to the inactive electrode. The CR circuit receives, as a first input, an EMI feedback signal from the EMI antenna. The CR circuit is configured to regulate the discharge current flow through the active electrode based on the EMI feedback signal, to maintain the AEPD profile over the discharge operation while in a presence of an EMI event.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/08 - Aménagements ou circuits de surveillance, de protection, de commande ou d'indication
78.
METHODS, SYSTEMS, AND DEVICES FOR DETECTING SLEEP AND APNEA EVENTS
Described herein are apparatuses and methods for classifying a patient as being asleep or awake. Such an apparatus can include an accelerometer and a processor. The accelerometer, alone or in combination with the processor, is used to determine an activity level of the patient and a posture of the patient. The processor is configured to classify the patient as being asleep in response to both (i) the posture of the patient being recumbent or reclined for at least a sleep latency duration, and (ii) the activity level of the patient not exceeding an activity threshold for at least the sleep latency duration; and classify the patient as being awake in response to at least one of (iii) the posture of the patient being upright for at least an awake latency duration, or (iv) the activity level of the patient exceeding the activity threshold for at least the awake latency duration.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre
A61B 5/366 - Détection de complexes QRS anormaux, p.ex. élargissement
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
79.
CATHETER INCLUDING WIRE MANAGEMENT CAP AND METHODS OF ASSEMBLING SAME
A catheter handle includes a housing extending from a proximal end to a distal end along a longitudinal axis. The housing defines an internal cavity. The catheter handle also includes at least one wire extending through the internal cavity between the proximal end and the distal end. The catheter handle further includes a wire management cap positioned within the internal cavity between a movable component of the catheter handle and one of the proximal and distal ends. The wire management cap defines a wire receiver cavity sized to receive a portion of the wire therein. The wire management cap is oriented such that the portion of the wire n the wire receiver cavity is separated from the movable component by the wire management cap to prevent interference between the movable component and the wire.
The instant disclosure relates to electrophysiology catheters for tissue ablation within a cardiac muscle, for example. In particular, the instant disclosure relates to an electrophysiology ablation balloon catheter with a combination of coated and uncoated surfaces for focusing ablation energy at a desired portion of tissue.
Method and system for providing continuous calibration of analyte sensors includes calibrating a first sensor, receiving data associated with detected analyte levels from the first sensor, and calibrating a second sensor based on a predetermined scaling factor and data associated with detected analyte levels from the first sensor, is disclosed.
A61B 5/1495 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang Étalonnage ou test des sondes in vivo
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61M 5/172 - Moyens pour commander l'écoulement des agents vers le corps ou pour doser les agents à introduire dans le corps, p.ex. compteurs de goutte-à-goutte électriques ou électroniques
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p.ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
82.
APPARATUS AND DEVICES FOR PROCESSING FLUID SAMPLES
Disclosed herein is an apparatus for processing fluid samples such as blood or blood products. Also disclosed are devices comprising the apparatus as well as methods for separating plasma from blood or blood products using said apparatus.
Fixation system for engaging tissue of a patient including an implantable fixation device having a first arm and a second arm, a first proximal element, a second proximal element, and a coupling member. The system includes a delivery device having a catheter, a shaft extending through the at least one lumen of the catheter, a first proximal element actuator and a second proximal element actuator. The second end portions of the first proximal element actuator and second proximal element actuator can be coupled to at least one of the shaft and the coupling member.
A system and method are provided that include a power supply having positive and negative terminals. The negative terminal defines a reference ground. First and second electrodes are positioned within a patient and configured to be located proximate to tissue of interest that is associated with a target region. A control circuit is configured to control delivery of current for a therapy between the first and second electrodes. A current regulator (CR) circuit is connected to, and configured to control current flow through, at least the first electrode during delivery of the therapy under direction of the control circuit. A floating power supply is connected across power supply terminals of the CR circuit. The CR circuit and floating power supply are coupled to a floating ground node that is electrically separate from the reference ground.
A61N 1/08 - Aménagements ou circuits de surveillance, de protection, de commande ou d'indication
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
H02M 1/44 - Circuits ou dispositions pour corriger les interférences électromagnétiques dans les convertisseurs ou les onduleurs
H02M 3/07 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des résistances ou des capacités, p.ex. diviseur de tension utilisant des capacités chargées et déchargées alternativement par des dispositifs à semi-conducteurs avec électrode de commande
A biostimulator and a biostimulator system for septal pacing, is described. The biostimulator includes a joint to allow an electrode to pivot relative to a housing. The housing contains electrical circuitry that is electrically connected to the pacing electrode. The joint allows the pacing electrode to affix to target tissue of an interventricular septal wall of a heart when the housing is pivoted toward an apex of the heart. Other embodiments are also described and claimed.
Computer implemented methods and systems for detecting noise in cardiac activity are provided. The method and system obtain a far field cardiac activity (CA) data set that includes far field CA signals for a series of beats, overlay a segment of the CA signals with a noise search window, and identify turns in the segment of the CA signals. The method and system determine whether the turns exhibit a turn characteristic that exceed a turn characteristic threshold, declare the segment of the CA signals as a noise segment based on the determining operation, shift the noise search window to a next segment of the CA signal and repeat the identifying, determining and declaring operations; and modify the CA signals based on the declaring the noise segments.
A collapsible prosthetic heart valve includes a collapsible and expandable stent and a collapsible and expandable valve assembly. The stent has a proximal end and a distal end. A plurality of commissure points is disposed on the stent. The valve assembly is disposed within the stent and includes a plurality of leaflets. Each leaflet has a free edge. An end portion of the free edge of each leaflet is folded and sutured to a corresponding one of the plurality of the commissure points.
A continuous analyte sensor system for monitoring a level of an analyte in a bodily fluid of a user. The system comprises a sensor electronics system and an analyte sensor. The sensor comprises a distal portion for positioning under a user's skin surface in contact with a bodily fluid for monitoring a level of an analyte in the bodily fluid and a proximal portion for positioning above the skin surface and in operative connection with the sensor electronics system. The sensor electronics system receives sensor signals indicative of the analyte level from the analyte sensor and generates data relating to the analyte level. The sensor electronics system comprises a transceiver for transmitting outgoing signals including the data relating to the analyte level and for receiving incoming signals. The transceiver comprises an electromagnetic signal generating component having first and second signal feed points. The sensor electronics system operates in a first and/or second communication mode. In the first communication mode, the sensor electronics system supplies first outgoing signals to the first signal feed point. In the second communication mode, the sensor electronics system supplies second outgoing signals to the second signal feed point.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/1486 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des électrodes enzymatiques, p.ex. avec oxydase immobilisée
H01Q 5/35 - Alimentation simultanée en plusieurs points
89.
SYSTEM AND METHOD OF DETERMINING/TRACKING USAGE CAPABILITY OF MEDICAL DEVICES
A method of monitoring total usage capability of a medical device includes monitoring one or more device attributes during a procedure and detecting device manipulations during the procedure based on the one or more device attributes. The method further includes determining whether the medical device may be reprocessed for subsequent use based, at least in part, on the detected device manipulations.
Implantable occlusion devices that include one or more flanges extending from a tubular body are disclosed. The flange or flanges may assist in retention of the device within a vessel, cavity, appendage, etc. At least one flange on the occlusion device may include a concave surface proximate one end of a body. Because of the shape of the flange, e.g., its concavity, the occlusion device may resist dislocation due to e.g., the forces generated within the left atrial appendage during atrial fibrillation.
A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p.ex. les vaisseaux sanguins ou le cordon ombilical
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets
91.
Methods and Compositions for Improving Insulin Production and Secretion
A method of improving insulin production in a subject in need thereof comprises administering a nutritional composition comprising lysine, arginine, and beta-hydroxy-beta-methylbutyrate (HMB) to the subject. A method of improving insulin secretion in a subject in need thereof comprises administering a nutritional composition comprising lysine, arginine, and HMB to the subject. A nutritional composition comprises about 0.01 to about 15 wt % HMB, about 0.03 to about 40 wt % lysine, and about 0.02 to about wt % arginine.
A61K 31/047 - Composés hydroxylés, p.ex. alcools; Leurs sels, p.ex. alcoolates ayant plusieurs groupes hydroxyle, p.ex. sorbitol
A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
A61K 47/42 - Protéines; Polypeptides; Leurs produits de dégradation; Leurs dérivés p.ex. albumine, gélatine ou zéine
A61K 47/44 - Huiles, graisses ou cires couvertes par plus d’un des groupes ; Huiles, graisses ou cires naturelles ou naturelles modifiées, p.ex. huile de ricin, huile de ricin polyéthoxylée, cire de lignite, lignite, gomme-laque, colophane, cire d’abeille ou lanoline
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p.ex. antidiabétiques
92.
SYSTEM, APPARATUS, AND DEVICES FOR ANALYTE MONITORING
A continuous analyte sensor system for monitoring a level of an analyte in a bodily fluid of a user. The system comprises a sensor electronics system and an analyte sensor. The sensor electronics system comprises a transceiver for transmitting outgoing signals including the data relating to the analyte level and for receiving incoming signals. The transceiver comprises an electromagnetic signal generating component having first and second signal feed points. The sensor electronics system operates in a first and/or second communication mode. In the first communication mode, the sensor electronics system supplies first outgoing signals to the first signal feed point. In the second communication mode, the sensor electronics system supplies second outgoing signals to the second signal feed point.
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/1486 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des électrodes enzymatiques, p.ex. avec oxydase immobilisée
H04W 4/80 - Services utilisant la communication de courte portée, p.ex. la communication en champ proche, l'identification par radiofréquence ou la communication à faible consommation d’énergie
93.
USE OF CARDIAC TROPONIN AND GALECTIN-3 TO DIFFERENTIATE MYOCARDIAL INFARCTION TYPE I AND TYPE II
The invention provides methods for determining whether a subject suspected of having a myocardial infarction is experiencing a Type I or Type II myocardial infarction. In particular, systems and methods are provided that employ a probability score based on decision tree based algorithms to process a subject's sex, age, and cardiac troponin concentration(s) and subject's galectin-3 (Gal-3) concentration.
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
94.
SYSTEM AND METHOD TO SELECTIVELY DISPLAY MAPPING DATA BASED ON ELECTRODE ORIENTATION RELATIVE TO ADJACENT TISSUE
A method of utilizing orientation of groups of electrodes to selectively display beat/depolarization event data includes observing beat/depolarization event data at a plurality of electrodes located in an electrode array and determining a position of each of the plurality of electrodes. The method further includes calculating an orientation of each sub-set of electrodes relative to adjacent tissue and then determining whether to display beat/depolarization event data collected by each sub-set of electrodes based on the orientation of each sub-set of electrodes relative to the adjacent tissue.
A61B 5/367 - Modalités électriques se rapportant au cœur, p.ex. électrocardiographie [ECG] Études électrophysiologiques [EEP], p.ex. cartographie de l’activation électrique ou cartographie électroanatomique
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
95.
METHODS FOR DETERMINING SARS-COV-2 ANTIGEN AND ANTI-SARS-COV-2 ANTIBODY IN A SAMPLE
Disclosed herein are methods, kits, and systems for detecting at least one type of SARS-CoV-2 antigen and at least one type of anti-SARS-CoV-2 antibody in a subject, which comprises the use of at least two different types of microparticle reagents for binding at least one type of SARS-CoV-2 antigen and at least one type of anti-SARS-CoV-2 antibody and at least two different types of detection reagents for binding each of the microparticle reagents.
G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
96.
SYSTEMS, DEVICES, AND METHODS FOR REVISING OR SUPPLEMENTING ROM-BASED RF COMMANDS
Systems, devices, and methods are provided that enable the revision of RF command handling software stored in ROM, and that enable to supplementation of RF command handling software stored in ROM. Examples of the systems, devices, and methods make use of a lookup data structure stored within writable non-volatile memory.
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
G06F 13/16 - Gestion de demandes d'interconnexion ou de transfert pour l'accès au bus de mémoire
G06F 13/42 - Protocole de transfert pour bus, p.ex. liaison; Synchronisation
97.
METHOD AND APPARATUS FOR PROVIDING DATA PROCESSING AND CONTROL IN A MEDICAL COMMUNICATION SYSTEM
Techniques for data processing and control for a glucose monitoring system are provided, including obtaining a first sensitivity of a glucose sensor; obtaining a second sensitivity of the glucose sensor; comparing a difference between the first sensitivity and the second sensitivity to a predetermined range of values; if the difference is outside the predetermined range of the values, causing a calibration routine for the glucose sensor to be performed; and if the difference is within the predetermined range of values determining a composite sensitivity for a current calibration of the glucose sensor based on the first sensitivity and the second sensitivity and calculating the glucose level based on the current calibration of the glucose sensor.
G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
A61B 5/145 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang
A61B 5/1473 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang en utilisant des procédés chimiques ou électrochimiques, p.ex. par des moyens polarographiques invasifs, p.ex. introduits dans le corps par un cathéter
A61B 5/1495 - Mesure des caractéristiques du sang in vivo, p.ex. de la concentration des gaz dans le sang, de la valeur du pH du sang Étalonnage ou test des sondes in vivo
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p.ex. pour des analyses d’échantillon de patient
G16H 20/10 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des médicaments ou des médications, p.ex. pour s’assurer de l’administration correcte aux patients
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
98.
IMPLANTABLE MEDICAL DEVICE DATA AND DIAGNOSTICS MANAGEMENT SYSTEM METHOD USING MACHINE-LEARNING ARCHITECTURE
A medical data and diagnostics management system for processing classified electrogram (EGM) datasets includes a server system that receives transmissions of classified EGM datasets, each corresponding to an arrhythmic episode detected by an implantable medical device (IMD), and applies a machine-learning model to each classified EGM dataset, thereby determining confidence indicator(s) relating to the IMD classification for each arrhythmic episode. Based upon the confidence indicator(s), the server system generates a set of machine-adjudicated EGM datasets, assigns a ranking score to each machine-adjudicated EGM dataset, and selects for display (for clinical analysis) a subset of the machine-adjudicated EGM datasets based upon their ranking scores. The machine-adjudicated EGM datasets are also stored in a database and further processed to generate diagnostic information and/or diagnostic alerts relating to the arrhythmic episodes detected by the IMD over time. The server system may also facilitate reprogramming of the IMD to improve its performance.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
99.
METHOD AND SYSTEM UTILIZING A DEVICE-BASED ATRIO-VENTRICULAR DELAY ADJUSTMENT
A method and device for dynamic device based AV delay adjustment are provided. The method provides electrodes that are configured to be located proximate to an atrial (A) site and a right ventricular (RV) site. The method utilizes one or more processors, in an implantable medical device (IMD), for detecting an atrial paced (Ap) event or atrial sensed (As) event. The method determines a measured AV interval corresponding to an interval between the Ap event or the As event and a ventricular sensed event and calculates a percentage-based (PB) offset based on the measured AV interval. The method automatically dynamically adjusting an AV delay, utilized by the IMD, based on the measured AV interval and the PB offset and manages a pacing therapy, utilized by the IMD, based on the AV delay after the adjusting operation.
A61N 1/368 - Stimulateurs cardiaques commandés par un paramètre physiologique, p.ex. par le potentiel cardiaque comprenant plus d'une électrode coopérant avec différentes régions du cœur
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p.ex. par le potentiel cardiaque
100.
FRAME AND PATCH DESIGN FOR OCCLUDER WITH ACCESS PASSAGE
Braided occluding devices having an access passage and methods including the same are described herein. The occluding device includes a braided frame. The braided frame includes an annular distal disc portion, a waist member, and an annular proximal disc portion defining a passageway through the braided frame. The braided frame is formed with a closed end braid.
A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p.ex. les vaisseaux sanguins ou le cordon ombilical
