Abrégé

The present invention relates to an implantable medical device comprising a layer consisting of or comprising zirconia, and to a method for the preparation thereof.

Classes IPC  ?

• A61C 8/00 - Moyens destinés à être fixés à l'os de la mâchoire pour consolider les dents naturelles ou pour y assujettir des prothèses dentaires; Implants dentaires; Outils pour l'implantation
• A61C 13/00 - Prothèses dentaires; Leurs procédés de fabrication
• C04B 35/48 - Produits céramiques mis en forme, caractérisés par leur composition; Compositions céramiques; Traitement de poudres de composés inorganiques préalablement à la fabrication de produits céramiques à base d'oxydes à base d'oxydes de zirconium ou d'hafnium ou de zirconates ou d'hafnates

Abrégé

The present invention relates to an isolated double stranded DNA polynucleotide that forms triplex with sequence 5′-GGUGGCAGCAAGAGAAAAAUGAGGAAGAAGCAAAAGCGGAAA-3′ (SEQ ID NO: 1) of the long non-coding RNA ANRIL (Antisense Non-coding RNA in the INK4 Locus). It also relates to a vector comprising the double stranded DNA polynucleotide, and to a pharmaceutical composition comprising the double stranded DNA polynucleotide or the vector. The present invention relates as well to the isolated double stranded DNA polynucleotide for use in the treatment of myocardial infarction, aneurysms, stenosis, myocardial infarction, aneurysms, cancers, eye diseases or type 2 diabetes.

Classes IPC  ?

• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p.ex. oligonucléotides anti-sens
• A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
• A61P 35/00 - Agents anticancéreux
• C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteurs; Vecteurs; Utilisation d'hôtes pour ceux-ci; Régulation de l'expression

Abrégé

An electrode including a storage film. The storage film includes a layer of a support material including at least one inclusion in which a compound of interest is stored and a wall of permeable sealing material sealing the at least one inclusion. The storage film further includes a porous layer covering, at least in part, the wall of sealing material, at least a portion of a surface of the porous layer constituting an active surface of the electrode.

Classes IPC  ?

• H01M 8/16 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Éléments à combustible; Leur fabrication Éléments à combustible biochimique, c. à d. éléments dans lesquels des micro-organismes agissent comme catalyseurs

Abrégé

This invention relates to a superconducting electric machine (1), for example with axial flux or with radial flux, comprising an inductor (3) comprising superconducting pellets (7) circumferentially distributed around an axis (X) of the electric machine (1) and a flux barrier (12) comprising a superconducting material, said flux barrier (12) being centered on the axis (X) of rotation and extending radially inward of the superconducting pellets (7).

Classes IPC  ?

• H02K 55/00 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques
• B64D 27/24 - Aéronefs caractérisés par le type ou la position des groupes moteurs utilisant la vapeur, l'électricité ou l'énergie de ressorts
• H01F 6/00 - Aimants supraconducteurs; Bobines supraconductrices

Abrégé

The present invention relates to a superconducting electric machine (1) comprising an inductor (3) having: —superconducting pellets (7) circumferentially distributed about an axis (X) of the electric machine (1), —an armature (2) comprising coils (5), each coil (5) having a circumferential radially inner edge (10) and a circumferential radially outer edge (9), and—at least one flow barrier (12, 12′) extending circumferentially with respect to the axis (X), each flow barrier (12) extending between the superconducting pellets (7) and the armature (2) so as to at least partially cover at least one of the radially outer edge (9) and the radially inner edge (10) of all or part of the coils (5) of the armature (2).

Classes IPC  ?

• H02K 55/02 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques du type synchrone
• B64D 27/24 - Aéronefs caractérisés par le type ou la position des groupes moteurs utilisant la vapeur, l'électricité ou l'énergie de ressorts

Abrégé

The invention relates to a magnetic component comprising a substrate (6) supporting at least one pair of permanent magnets (2) extending in a first direction (X), each magnet (2) having an interaction end (21a, 21b), the interaction ends (21a, 21b) being arranged facing one another, the pair of magnets (2) being arranged so as to exert an antisymmetric magnetic field with a high magnetic field gradient along a second direction (Z) orthogonal to the first direction (X), under the effect of a magnetic field produced by external magnetic means.

Classes IPC  ?

• H01F 41/34 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour appliquer un matériau conducteur, isolant ou magnétique sur une pellicule magnétique selon des configurations particulières, p.ex. par lithographie
• G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p.ex. couplage ou commande de qubit

Abrégé

A process for producing a protein isolate from an oilseed meal, and the isolate thus obtained, said isolate comprising proteins and an amount of 4 wt % or less of phytic acid, said amount of phytic acid being by weight of proteins in said isolate. The process may comprise the following steps: a) providing an oilseed meal; b) mixing the oilseed meal with a first aqueous solvent to form a slurry at a pH ranging from 6 to 7.8, said slurry having a solid phase; c) separating said solid phase from said slurry, d) mixing said separated solid phase with a second aqueous solvent at a pH ranging from 1 to 3.5, preferably from 2 to 3, to form a mixture said mixture having a liquid phase; e) separating said liquid phase from said mixture formed in step d); f) f1) mixing the separated liquid phase to a phytase at a temperature and a pH suitable for phytase activity to obtain a mixture having a liquid phase and a solid phase; and/or f2) mixing the separated liquid to a salt, to obtain a resulting liquid composition having a molar concentration of said salt ranging from 0.05 M to 0.5 M, at a temperature ranging from 40° C. to 70° C., to obtain a mixture having a liquid phase and a solid phase; g) precipitating a solid phase from the liquid of step f) for example by a cooling down step of the mixture to a temperature of 30° C. or less; h) separating said solid precipitate from the liquid of step g) said liquid comprising a water-rich liquid phase and an oil-rich liquid phase; i) separating said water-rich liquid phase from said oil-rich liquid phase, j) subjecting said water-rich liquid phase obtained in step i) to one or several membrane filtration(s) to obtain a protein isolate; and k) optionally, drying said protein isolate to obtain a dry protein isolate.

Classes IPC  ?

• A23J 1/14 - Préparation des compositions à base de protéines pour l'alimentation; Ouverture des œufs par grandes quantités et séparation du jaune du blanc à partir des tourteaux ou des graines oléagineuses
• C07K 1/34 - Extraction; Séparation; Purification par filtration, ultrafiltration ou osmose inverse

Abrégé

A non-magnetic part including an austenitic alloy, the austenitic alloy including between 50 and 85 wt % of iron, one or more gammagene elements the weight percentage or the total weight percentages of which amount to between 15 and 35 wt %, and less than 2 wt % of nitrogen. The austenitic alloy has a crystallographic structure including a predominantly cubic crystal structure and the presence of a hexagonal crystal structure. The magnetic part includes a hardness gradient in the direction extending radially from the surface of the at least one portion of the non-magnetic part to the inside of the non-magnetic part, the hardness gradient having a value greater than or equal to 100 HV.

Classes IPC  ?

• C21D 9/00 - Traitement thermique, p.ex. recuit, durcissement, trempe ou revenu, adapté à des objets particuliers; Fours à cet effet
• C22C 38/00 - Alliages ferreux, p.ex. aciers alliés
• C21D 6/00 - Traitement thermique des alliages ferreux
• C21D 8/00 - Modification des propriétés physiques par déformation en combinaison avec, ou suivie par, un traitement thermique

Abrégé

The present invention relates to the use of a multimeric protein of the peroxiredoxin family as a scaffold protein, characterized in that one or more proteins(s) of interest are linked to one or two N- and C-terminal end(s) of one or more monomers(s) of the peroxiredoxin, said peroxiredoxin having no redox activity.

Classes IPC  ?

• C12N 11/06 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique attachées au support au moyen d'un agent de pontage
• C12N 9/08 - Oxydoréductases (1.), p.ex. luciférase agissant sur le peroxyde d'hydrogène comme accepteur (1.11)
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli

Abrégé

The invention relates to a light emission system (10, 20) of the spin-LED or spin-laser type, comprising: - a stack (STA) comprising an active layer (AL) and transport layers; - an electrode referred to as anode (An) and an electrode referred to as cathode (Cath); - a so-called spin injector device (SID) deposited on the stack and comprising: an assembly of at least one first layer (L1) made of ferromagnetic material (Mfer) and at least one second layer (L2) made of metal material (Mmet), the assembly having a bar structure referred to as Hall bar (HB), a first electrode (EL1) and a second electrode (EL2), referred to as spin electrodes, configured to generate, in the Hall bar, a pulsed current I along the X axis in a first direction or a second direction opposite to the first direction; - the spin injector being configured so as to have magnetisation (M) along Z and so that a reversal of the direction of the current I causes a reversal of the direction of the magnetisation (M), a change in the magnetisation of the spin injector inducing a change in the state of circular polarisation of the light (EL) emitted by the emission system.

Classes IPC  ?

• H01S 5/042 - Excitation électrique
• H01S 5/062 - Dispositions pour commander les paramètres de sortie du laser, p.ex. en agissant sur le milieu actif en faisant varier le potentiel des électrodes
• H01S 5/183 - Lasers à émission de surface [lasers SE], p.ex. comportant à la fois des cavités horizontales et verticales comportant uniquement des cavités verticales, p.ex. lasers à émission de surface à cavité verticale [VCSEL]

Abrégé

The invention relates to a muscle membrane intended to be affixed to a muscle of a human or animal body, the membrane being capable of at least partially surrounding the muscle, the muscle comprising fibres covered with an outer tissue, the positioned membrane having a shape that is identical to that of the muscle. The membrane is characterised in that it exhibits anisotropic behaviour so as to reproduce the mechanical behaviour of the muscle, the membrane comprising: - a matrix designed in a biocompatible material having an elasticity similar to that of the outer tissue of the muscle, - one or more reinforcing strips rigidly attached to the matrix, each strip being designed in a biocompatible material having an elasticity similar to that of the fibres it covers and each strip being oriented according to membrane stiffening requirements and according to the expected muscle correction.

Classes IPC  ?

• A61L 27/34 - Matériaux macromoléculaires
• A61L 27/38 - Cellules animales
• A61P 17/02 - Médicaments pour le traitement des troubles dermatologiques pour traiter les blessures, les ulcères, les brûlures, les cicatrices, les cheloïdes, ou similaires
• D01D 5/00 - Formation des filaments, fils ou similaires
• B33Y 80/00 - Produits obtenus par fabrication additive
• A61F 5/00 - Procédés ou dispositifs d'orthopédie pour le traitement non chirurgical d'os ou articulations; Dispositifs pour donner des soins

Abrégé

It is disclosed a computer-implemented method for characterizing the evolution with duration of operation of the state of health of a population of devices, the method comprising training a model on a database comprising, for each device among the population of devices, a value of duration of operation of the device and a corresponding state of health of the device, said model being a random process comprising at least the sum of: - a term representing average evolution of the state of health of the population with duration of operation, and - a term representing an inter-device variability of the degradation of the state of health at equal duration of operation, the variance of said term evolving with the duration of operation.

Classes IPC  ?

• G01R 31/392 - Détermination du vieillissement ou de la dégradation de la batterie, p.ex. état de santé
• G01R 31/367 - Logiciels à cet effet, p.ex. pour le test des batteries en utilisant une modélisation ou des tables de correspondance

Abrégé

The present invention relates to the treatment of an arthritic disease such as rheumatoid arthritis with a kynurenine aminotransferase, a living recombinant bacterium which has been genetically modified to express and secrete said kynurenine aminotransferase, and/or a product of said kynurenine aminotransferase which is xanthurenic acid, a derivative thereof, or any pharmaceutically acceptable salt or solvate thereof.

Classes IPC  ?

• A61K 38/45 - Transférases (2)
• A61K 31/47 - Quinoléines; Isoquinoléines
• A61P 19/02 - Médicaments pour le traitement des troubles du squelette des troubles articulaires, p.ex. arthrites, arthroses
• C12N 9/10 - Transférases (2.)
• C12N 9/88 - Lyases (4.)

Abrégé

The present invention relates to a microcapsule that is made of bioavailable polymer, is loaded with at least one active substance and comprises at least one micrometric opening. The invention also relates to a method for obtaining said capsule and to said capsule for use in the treatment of a pathology, in particular cancer or myopathy.

Classes IPC  ?

• A61K 9/50 - Microcapsules
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/00 - Préparations médicinales contenant des ingrédients actifs organiques 
• A61P 1/00 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif

Abrégé

The invention relates to a method for thermoplasticization of a cellulose material, said method comprising: i) bringing a fatty acid (FA) into contact with trifluoroacetic anhydride (TFAA); and ii) esterification of a cellulose material by reaction with the mixed anhydride obtained in step i), whereby a thermoplastic cellulose material is obtained, steps i) and ii) being carried out in the absence of solvent, in particular at ambient temperature.

Classes IPC  ?

• C08H 8/00 - Composés macromoléculaires dérivés de matériaux lignocellulosiques
• C08L 1/10 - Esters des acides organiques
• C08L 97/02 - Matériau lignocellulosique, p.ex. bois, paille ou bagasse
• C08B 3/08 - Préparation d'esters cellulosiques d'acides organiques d'acides organiques monobasiques à 3, ou plus, atomes de carbone
• C08B 3/10 - Préparation d'esters cellulosiques d'acides organiques d'acides organiques monobasiques à 3, ou plus, atomes de carbone à 5, ou plus, atomes de carbone
• C08B 3/16 - Préparation d'esters cellulosiques organiques mixtes

Abrégé

The present invention pertains to cell culture protocols and particularly provides a method for obtaining Invariant Natural Killer T (iNKT) cells. The method according to the present invention particularly comprises culturing peripheral blood mononuclear cells (PBMC) in a culture medium comprising alpha-Galactosylceramide (alpha-GalCer) and Interleukin 15 (IL-15). The present invention allows for the specific expansion of CD4- iNKT which have a particular interest in the prevention of graft versus host disease in the context of hematopoietic stem cell transplantation.

Classes IPC  ?

• C12N 5/0783 - Cellules T; Cellules NK; Progéniteurs de cellules T ou NK

Abrégé

The present invention relates to a fusion protein, to a nucleic acid coding for the protein, to a vector comprising the nucleic acid, to a host cell comprising the nucleic acid and/or vector, to a process for producing a fusion protein and to a process for bioconverting a substrate. The fusion protein of the present invention successively comprises (i) at least one polypeptide for targeting, and attaching to, the bacterial membrane, (ii) at least one polypeptide corresponding to the hydrophilic domain of a plant P450 cytochrome, (iii) at least one binding polypeptide comprising at least 47 amino acids, and (iv) at least one polypeptide corresponding to the hydrophilic domain of a plant NADPH-dependent cytochrome P450 reductase.

Classes IPC  ?

• C07K 14/415 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de végétaux
• C12N 9/02 - Oxydoréductases (1.), p.ex. luciférase

Abrégé

The invention relates to a titanium alloy comprising, as contents by weight: - 4.0% to 5.0 % of aluminium; - 3.50% to 4.50% of tin; - 1.0% to 4.0% of zirconium, - 2.0% to 5.25% of molybdenum; - 1.0% to 2.50% of niobium; - 0.10% to 0.25% of silicon; - 0.10% to 0.18% of oxygen; the balance being constituted of titanium and unavoidable impurities, the alloy further verifying that the criterion Aleq known as "equivalent aluminium content by weight" is less than or equal to 8.5%, the criterion Aleq being defined as Aleq =[Al]+[Sn]/3+[Zr]/6+10*[O] where [Al], [Sn], [Zr] and [O] are the weight contents respectively of aluminium, tin, zirconium and oxygen.

Classes IPC  ?

• C22C 14/00 - Alliages à base de titane
• F01D 5/28 - Emploi de matériaux spécifiés; Mesures contre l'érosion ou la corrosion

Produits et services

Adhesives for stationery or household purposes; Decoration and art materials and media; Filtering materials of paper; Works of art and figurines of paper and cardboard, and architects' models; Paper and cardboard; Money holders; Printed matter, and stationery and educational supplies; Bags and articles for packaging, wrapping and storage, of paper, cardboard or plastics. Business assistance, management and administrative services; Advertising, marketing and promotional services. Provision and rental of telecommunications facilities and equipment; Telecommunication services. Publishing, reporting, and writing of texts; Education, entertainment and sports; Education, entertainment and sport services; Ticket reservation and booking services for education, entertainment and sports activities and events; Translation and interpretation. Design services; IT services; Scientific technological services; Testing, authentication and quality control. Safety, rescue, security and enforcement services; Legal services; Political services.

Abrégé

The invention relates to a microfluidic chip (1) for growing cells comprising a reservoir (2) capable of containing a solution, at least two separate chambers (3) capable of being supplied with the solution from the reservoir and capable of receiving one or more cells, at least two separate afferent channels (4) each connecting an outlet (5) of the reservoir, from among at least two separates outlets (5) of the reservoir, to a chamber from among the at least two separate chambers, and at least two separate efferent channels (6) each connecting a chamber from among the at least two separate chambers to a drain (7), the drain allowing the solution to be discharged from each of the at least two chambers.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Abrégé

The present invention relates to a composite material with a graded or homogeneous matrix, the production method thereof, and the uses of same.

Classes IPC  ?

• B29C 64/153 - Procédés de fabrication additive n’utilisant que des matériaux solides utilisant des couches de poudre avec jonction sélective, p.ex. par frittage ou fusion laser sélectif
• B22F 10/28 - Fusion sur lit de poudre, p.ex. fusion sélective par laser [FSL] ou fusion par faisceau d’électrons [EBM]
• B29C 71/00 - Post-traitement d'objets sans modification de leur forme; Appareils à cet effet
• B22F 10/62 - Traitement de pièces ou d'articles après leur formation par des moyens chimiques

Abrégé

A method for exfoliating and/or functionalising lamellar objects is discussed. The steps include immersing at least one portion of a first electrode in a liquid containing the lamellar objects to be exfoliated and/or functionalised, placing a second electrode outside the liquid, at least one portion of the second electrode being opposite a surface of the liquid, generating a plasma between at least one portion of the second electrode facing the surface of the liquid and the surface of the liquid by applying a pulse voltage difference between the first and the second electrode.

Classes IPC  ?

• C01B 32/194 - Post-traitement
• C01B 32/225 - Expansion; Exfoliation
• C01B 32/19 - Préparation par exfoliation
• B01J 19/08 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaire; Appareils à cet usage

Abrégé

The present disclosure aims to provide a technique for monitoring the behavior of a control system accurately. One aspect of the present invention relates to a monitoring device having: an acquiring part configured to acquire observed values of a variable that is sampled with respect to a behavior of a control system while the control system is running; and a determining part configured to determine a range of possible observed values that the variable possibly reaches upon a temporal change thereof, based on the acquired observed values, and determine whether a variation range of the acquired observed values satisfies a specification, based on an overlap between the range of the possible observed values and a range not satisfying the specification.

Classes IPC  ?

• G05B 23/02 - Test ou contrôle électrique
• G06F 11/07 - Réaction à l'apparition d'un défaut, p.ex. tolérance de certains défauts

Abrégé

It is provided a computer-implemented method for estimating a distribution of conductivity over a portion of a tissue of a body. The method comprises obtaining a magnetic resonance image (MRI) of the portion of tissue and a body surface electrical potential measurement associated with the MRI. The method also comprises estimating the distribution of conductivity on the portion of tissue based on the body surface electrical potential measurement and on the MRI. This forms an improved solution for estimating the distribution of conductivity over a portion of a tissue of a body.

Classes IPC  ?

• G01R 33/48 - Systèmes d'imagerie RMN
• A61B 5/0535 - Pléthysmographie par impédance
• G01N 3/08 - Recherche des propriétés mécaniques des matériaux solides par application d'une contrainte mécanique par application d'efforts permanents de traction ou de compression
• A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
• G01R 33/56 - Amélioration ou correction de l'image, p.ex. par des techniques de soustraction ou d'établissement de moyenne

Abrégé

The invention relates to a method for preparing graphene quantum dots (GQDs), the method comprising the steps of: i) suspending a carbon source in a mixture of water and sulphuric acid; ii) microwaving the obtained suspension to a temperature of between 20°C and 200°C, in particular between 100°C and 180°C; iii) recovering and optionally washing and/or drying the obtained carbonaceous residue; iv) suspending the obtained residue in nitric acid; v) microwaving the obtained suspension to a temperature of between 20°C and 200°C, in particular between 100°C and 180°C; and vi) recovering the obtained graphene-based quantum dots (GQDs).

Classes IPC  ?

• C01B 32/15 - Matières carbonées nanométriques
• C09K 11/65 - Substances luminescentes, p.ex. électroluminescentes, chimiluminescentes contenant des substances inorganiques luminescentes contenant du carbone

Abrégé

The invention relates to a method for the additive manufacturing of a magnetic object in which a layer of a mixture of powders is deposited on a printing support, the mixture comprising at least one thermoplastic polymer powder in order to form a matrix and at least one powder having magnetisable particles; and at least one region of the layer of the mixture of powders is selectively irradiated by laser. At least one region of the layer deposited on the printing support is subjected, at least while the polymer powder is in the liquid phase caused by laser irradiation, to a magnetic field. The power of the magnetic field is sufficient to orient the magnetic moments of the magnetisable particles. The printing support is made of a magnetically inert material and the magnetic field is generated by at least one magnet combined with the printing support.

Classes IPC  ?

• B22F 10/16 - Formation d’un corps vert par incorporation de liant dans un lit de poudre
• B22F 10/30 - Commande ou régulation des opérations
• B22F 12/30 - Plate-formes ou substrats
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additive; Leurs parties constitutives ou accessoires à cet effet
• B33Y 80/00 - Produits obtenus par fabrication additive
• H01F 1/04 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriés; Emploi de matériaux spécifiés pour leurs propriétés magnétiques en matériaux inorganiques caractérisés par leur coercivité en matériaux magnétiques durs métaux ou alliages
• H01F 1/08 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriés; Emploi de matériaux spécifiés pour leurs propriétés magnétiques en matériaux inorganiques caractérisés par leur coercivité en matériaux magnétiques durs métaux ou alliages sous forme de particules, p.ex. de poudre comprimées, frittées ou agglomérées
• H01F 41/02 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants

Abrégé

The invention relates to a method for issuing, from multimedia content available on a multimedia content host website (11), multimedia quiz cards (flashcards) (7) that provide learning contexts suitable for a learner of a foreign language according to a plurality of criteria, this method comprising the following steps: - searching (12) indexed multimedia content available on said host site (11), according to a plurality of predetermined target words, - pre-filtering (6), from among the indexed multimedia content (4) resulting from the search step (12), indexed multimedia content corresponding to a plurality of learning contexts, - producing (13), from each of said indexed and pre-filtered multimedia content items, quiz cards (flashcards) (7), each of which incorporates a quiz relating to one or more target words associated with the respective multimedia content, said quiz cards produced in this way being provided to be visualised on an electronic device used by the learner (S), - identifying (5), using a neural learning method, and from among the quiz cards produced in this way (7), one or more quiz cards suitable for allowing the learner (S) to advance on the basis of their profile.

Classes IPC  ?

• G09B 19/06 - Langues étrangères
• G09B 5/06 - Matériel à but éducatif à commande électrique avec présentation à la fois visuelle et sonore du sujet à étudier
• G06F 16/783 - Recherche de données caractérisée par l’utilisation de métadonnées, p.ex. de métadonnées ne provenant pas du contenu ou de métadonnées générées manuellement utilisant des métadonnées provenant automatiquement du contenu
• G06F 40/30 - Analyse sémantique
• G06F 40/58 - Utilisation de traduction automatisée, p.ex. pour recherches multilingues, pour fournir aux dispositifs clients une traduction effectuée par le serveur ou pour la traduction en temps réel

Abrégé

A method and system for assisting learning of endoscopic surgery, in particular endonasal surgery, during exercises each including a set of instrument movements of the endoscope and/or of one or more surgical instruments, carried out by the operator. The system includes a hardware simulator including one or more thematic models, in particular interchangeable modules on a support head. It also includes a computerised management unit which communicates with the endoscope and/or the instrument and/or the module or model. For each exercise, it displays the actions to be performed, and detects various endoscope and/or instrument movements and/or contacts. One module presents targets to be visualised in a framed manner, the display of which is validated by shape recognition in the software. Other modules include objects to be dissected or moved, while avoiding obstacles. The movements of instruments, grippers and/or contacts, are recorded by the software in order to evaluate the exercise.

Classes IPC  ?

• A61B 18/14 - Sondes ou électrodes à cet effet
• A61B 17/29 - Pinces pour la chirurgie faiblement invasive

Abrégé

The invention relates to a method for depositing a coating on inner surfaces forming cavities of a heat exchanger, characterized in that the coating comprises a liquid adhesive and a powder of a pulverulent solid intended to act as a catalyst for a physico-chemical reaction.

Classes IPC  ?

• B01J 37/02 - Imprégnation, revêtement ou précipitation
• C23C 20/00 - Revêtement chimique par décomposition soit de composés solides, soit de suspensions des composés constituant le revêtement, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement
• F28D 9/00 - Appareils échangeurs de chaleur comportant des ensembles de canalisations fixes en forme de plaques ou de laminés pour les deux sources de potentiel calorifique, ces sources étant en contact chacune avec un côté de la paroi d'une canalisation
• F28F 3/02 - Eléments ou leurs ensembles avec moyens pour augmenter la surface de transfert de chaleur, p.ex. avec des ailettes, avec des évidements, avec des ondulations
• B01J 23/745 - Fer

Abrégé

The present invention relates to the prediction of drug metabolizing enzymes (DME) inhibitors. Inhibition of DMEs leads to adverse drug-drug interaction, hence predicting inhibition of DMEs by determined molecules is critical for preventing drug toxicity. Inventors elaborated a protocol of integrated in silico protein structure-based and machine learning approach to predict inhibition of DMEs. In particular, the present invention relates to a method for training a model for predicting inhibition of DMEs, comprising a selection of a number of descriptors among an initial set comprising physicochemical descriptors and binding energies on at least one enzyme configuration, and a training of a classification model on a learning database of known inhibitors or non-inhibitors based on the selected descriptors as inputs. This approach successfully predicted inhibition of CYP2C9, CYP2D6, SULT1A1, SULT1A3 and UGT1 A1.

Classes IPC  ?

• G16B 15/30 - Ciblage de médicament à l’aide de données structurelles; Prévision d’amarrage ou de liaison moléculaire
• G16B 40/20 - Analyse de données supervisée
• G06F 18/2411 - Techniques de classification relatives au modèle de classification, p.ex. approches paramétriques ou non paramétriques basées sur la proximité d’une surface de décision, p.ex. machines à vecteurs de support

Abrégé

The use of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as a marker in a method for identifying a subject suffering from a disease caused by a coronavirus such as COVID-19 at risk of having or developing a severe form and/or a complication or at risk of death, in a method for assessing the severity of a disease caused by a coronavirus such as COVID-19, and in a method for monitoring a subject suffering from a disease caused by a coronavirus such as COVID-19.

Classes IPC  ?

• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus

Abrégé

The invention relates to a test device comprising a tribometer (1) associated with a sample to be tested, said tribometer comprising: • - a frame (10); • - a piston (2); • - a jaw (3b) which is fixed relative to the frame (10) and carries a first die (19b); • - a jaw (3a) which is movable relative to the frame (10) and carries a second die (19a). The sample (6) is positioned between the two dies (19a, 19b) and has two side ends, each end being in contact with a die (19a, 19b). The piston (2) slides the sample (6) along the dies (19a, 19b). This test device also includes a sample holder (11) holding the sample (6) and being moved by the piston (2), the sample holder (11) and the piston (2) having complementary shapes in order to wedge the sample holder (11) in place.

Classes IPC  ?

• G01N 19/02 - Mesure du coefficient de frottement entre matériaux

Abrégé

The invention relates to an anti-counterfeiting object built by additive manufacturing by depositing a first electrically insulating material in a molten state. The object comprises at least one conductor (15, 16, 17) made of a second conductive material integrated into the first material, the conductor (15, 16, 17) connecting at least two accessible terminals (11, 12, 13, 14) and having a measurable characteristic resistance between the terminals (11, 12, 13, 14). The invention also relates to a method for authenticating said object.

Classes IPC  ?

• G07D 7/023 - Mesure de la conductivité par contact direct
• G09C 1/00 - Appareils ou méthodes au moyen desquels une suite donnée de signes, p.ex. un texte intelligible, est transformée en une suite de signes inintelligibles en transposant les signes ou groupes de signes ou en les remplaçant par d'autres suivant un systèm
• H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système

Abrégé

The present invention relates to an axial-flux superconducting electric machine (1) comprising an inductor (6, 7) and an armature (5), the inductor (6, 7) comprising:• superconducting pads (7) able to move in rotation about an axis (X) of the electric machine (1); and• a superconducting coil (6), centred on the axis (X) and extending radially outside the superconducting pads (7), the superconducting coil (6) being configured to generate a magnetic field. The electric machine (1) additionally furthermore comprises a flux barrier (12) made of a superconducting material and extending between the superconducting pads (7) and the superconducting coil (6), said flux barrier (12) being attached to a circumferential wall (7a) of the superconducting pads (7) so as to move together with the superconducting pads (7).

Classes IPC  ?

• H02K 1/2793 - Rotors faisant face axialement à des stators
• H02K 21/04 - Bobinages disposés sur les aimants pour une excitation additionnelle
• H02K 55/02 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques du type synchrone
• H02K 55/06 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques du type homopolaire
• H01F 6/02 - Etouffement de la supraconductivité; Dispositions pour la protection lors de la phase de transition vers l'état de conductivité normale
• H01F 6/06 - Bobines, p.ex. dispositions pour l'enroulement, l'isolation, les enveloppes ou les bornes des bobines

Abrégé

The invention relates to a DC-to-DC converter (209) for an electrical aircraft propulsion system designed to be connected in series with an electrical energy storage unit of the electrical propulsion system. The DC-to-DC converter (209) comprises an inverter (401), a transformer (403) and a rectifier (405), and further comprises a current source (417) that is connected to the rectifier (405) and is configured to control the power passing through the DC-to-DC converter (209). The transformer (403) comprises a primary (403a) and two secondaries (403b, 403c), the two secondaries (403b, 403c) sharing a common terminal (407) designed to be connected to a high-voltage DC bus (207) of the electrical propulsion system (201) and two other terminals (409, 411) that are connected to the rectifier (405). The rectifier (405) comprises two arms comprising at least two transistors (415a, 415b, 415c, 415d) that are each in series and are connected, on the one hand, to the two other terminals (409, 411) of the transformer (403) and, on the other hand, to the current source (417).

Classes IPC  ?

• H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
• H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
• B64D 27/24 - Aéronefs caractérisés par le type ou la position des groupes moteurs utilisant la vapeur, l'électricité ou l'énergie de ressorts
• H02M 7/219 - Transformation d'une puissance d'entrée en courant alternatif en une puissance de sortie en courant continu sans possibilité de réversibilité par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs dans une configuration en pont

Abrégé

The invention relates to a system for learning braille, comprising at least one removable element (2) having at least one braille inscription, a main device (1) capable of receiving and identifying the removable element (2), a speaker (S) and an installed unit (5), internal to the main device (1), communicating with a receiver in a housing (7). The system comprises a user identification device (3), independent of said main device (1), which includes a communication module (30) that comprises an identification signal transmitter, a receiver of an update signal for updating user-specific learning level information, and a memory. The installed unit (5) is capable of receiving and processing a user identification signal and is capable of transmitting said update signal in response. A communication module of the identification device communicates with said installed unit using short-range signal-transfer technology.

Classes IPC  ?

• G09B 21/00 - Moyens d'enseignement ou de communication destinés aux aveugles, sourds ou muets

Abrégé

The present invention concerns new peptides derived from the netrin-like domain of the FRZB protein, that are useful in the prevention or treatment of Wnt/β-catenin and/or Hippo/YAP/TAZ pathway-related diseases, in particular of osteoarthritis.

Classes IPC  ?

• C07K 14/47 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains provenant de vertébrés provenant de mammifères

Abrégé

A flame retardant treatment of a lignocellulosic material, which includes: optionally steam exploding the lignocellulosic material, impregnating the optionally steam-exploded lignocellulosic material, in or with an aqueous solution, from 0.5% to 10% of phytic acid and from 1% to 30% of urea, based on the total weight of the aqueous solution, optionally drying of the impregnated lignocellulosic material, until the impregnated lignocellulosic material has a moisture content from 5% to 20% by weight, cooking the impregnated and optionally dried lignocellulosic material, the resulting flame-retarded lignocellulosic material including a phosphorous content originating from the phytic acid from 0.1% to 10% by weight. Also, the resulting flame-retarded lignocellulosic material and the use thereof for manufacturing flame-retarded composite materials based on plant fibres, woven or nonwoven flame-retarded flexible materials based on plant fibres, and particularly textiles, flame-retarded materials based on wood fibres and/or on wood particles, and particularly flame-retarded wood panels.

Classes IPC  ?

• B27K 3/02 - Procédés; Appareillage
• B27K 3/34 - Agents d'imprégnation organiques
• B27K 3/36 - Composés aliphatiques
• B27K 3/38 - Composés aromatiques
• B27K 3/50 - Mélanges de différents agents d'imprégnation organiques

Abrégé

The invention relates to an electric machine that comprises a rotor (7), a stator (2), and a vacuum chamber (10), the rotor (7) and/or the stator (2) comprising a superconducting material, the rotor (7) and/or the stator (2) that comprises the superconducting material being placed in the vacuum chamber (10). The electric machine further comprises a cooling system (11), placed in the vacuum chamber (10), for cooling the rotor and/or the stator, and a valve (12) passing through a peripheral wall (13) of the vacuum chamber (10).

Classes IPC  ?

• H02K 7/18 - Association structurelle de génératrices électriques à des moteurs mécaniques d'entraînement, p.ex. à des turbines
• H02K 55/02 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques du type synchrone
• H02K 55/04 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques du type synchrone avec des enroulements à champ tournant

Abrégé

The present invention concerns a computer based method for evaluating the stability of at least one structure of at least one complex constituted of a molecule and its environment.

Classes IPC  ?

• G16C 20/30 - Prévision des propriétés des composés, des compositions ou des mélanges chimiques
• G16B 15/30 - Ciblage de médicament à l’aide de données structurelles; Prévision d’amarrage ou de liaison moléculaire

Abrégé

This method for de-energizing an electric machine comprising a superconducting inductor and an armature comprises a step (12) of injecting an electric current into the armature so as to generate losses in the superconducting inductor until the temperature of the superconducting inductor increases above a predefined temperature threshold at which the inductor stops superconducting.

Classes IPC  ?

• H02P 3/24 - Dispositions pour l'arrêt ou le ralentissement de moteurs, génératrices électriques ou de convertisseurs dynamo-électriques pour arrêter ou ralentir individuellement un moteur dynamo-électrique ou un convertisseur dynamo-électrique pour arrêter ou ralentir un moteur à courant alternatif par application de courant continu au moteur
• H02P 9/10 - Commande s'exerçant sur le circuit d'excitation de la génératrice afin de réduire les effets nuisibles de surcharges ou de phénomènes transitoires, p.ex. application, suppression ou changement brutal de la charge

Abrégé

The present invention relates to a method for removing lactosyl-bearing proteins from dairy protein concentrates and to the product, which is depleted in both lactose and lactosyl-bearing protein, obtained by said method.

Classes IPC  ?

• A23C 3/00 - Conservation du lait ou de préparations à base de lait
• A23C 7/04 - Enlèvement du lait des substances indésirables
• A23C 9/142 - Préparations à base de lait; Lait en poudre ou préparations à base de lait en poudre dans lesquelles la composition chimique du lait est modifiée par des traitements non chimiques par dialyse, osmose inverse ou ultrafiltration
• A23C 9/148 - Préparations à base de lait; Lait en poudre ou préparations à base de lait en poudre dans lesquelles la composition chimique du lait est modifiée par des traitements non chimiques par tamis moléculaire ou filtration sur gel
• A23L 5/20 - Préparation ou traitement des aliments ou produits alimentaires en général; Aliments ou produits alimentaires ainsi obtenus; Leurs matériaux Élimination de constituants indésirables, p.ex. désodorisation ou détoxication
• A23C 9/12 - Préparations à base de lait fermenté; Traitements utilisant des micro-organismes ou des enzymes
• C07K 14/705 - Récepteurs; Antigènes de surface cellulaire; Déterminants de surface cellulaire

Abrégé

The invention relates to a method for determining optimised positions of at least one object provided with a field of view for tracking a path in a simulated environment comprising obstacles, the field of view comprising a source, a range and an aperture angle. The method is implemented by a computer and comprises the following steps: a) selecting a set of candidate positions; b) for each candidate position, constructing a local field of view placed at this candidate position and oriented to encompass as large a segment as possible; c) assigning a score to each candidate position; and d) travelling along the main path, segment by segment, selecting for each segment a candidate position having the highest score.

Classes IPC  ?

• G08B 13/196 - Déclenchement influencé par la chaleur, la lumière, ou les radiations de longueur d'onde plus courte; Déclenchement par introduction de sources de chaleur, de lumière, ou de radiations de longueur d'onde plus courte utilisant des systèmes détecteurs de radiations passifs utilisant des systèmes de balayage et de comparaison d'image utilisant des caméras de télévision
• H04N 7/18 - Systèmes de télévision en circuit fermé [CCTV], c. à d. systèmes dans lesquels le signal vidéo n'est pas diffusé
• G05D 1/02 - Commande de la position ou du cap par référence à un système à deux dimensions
• G01C 21/00 - Navigation; Instruments de navigation non prévus dans les groupes

Abrégé

A protein capable of converting chlorogenic acid into isochlorogenic acid. The protein includes or is an amino acid sequence SEQ ID No. 1, a sequence having at least 80% identity with this sequence or a fragment of this sequence. Also, a process for producing isochlorogenic acid from chlorogenic acid, which includes producing the protein and bringing it into contact with chlorogenic acid.

Classes IPC  ?

• C12P 7/62 - Esters d’acides carboxyliques
• C12N 9/18 - Hydrolases agissant sur les esters d'acides carboxyliques
• C12N 15/81 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour champignons pour levures
• C12N 15/82 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules végétales

Abrégé

Disclosed is a rotating electrical machine with axial air gap, comprising two rotors, each provided with superconducting axial magnetic flux barrier elements around an axis of rotation and having, between them, axial magnetic flux passage areas, at least one armature, comprising windings and a superconducting field coil surrounding the elements and the armature and capable of inducing an axial magnetic field. Each armature is positioned between two of the rotors. The superconducting elements of the rotors are coaxial with one another and also the flux passage areas. A first annular cryogenic enclosure encloses the field coil and a second cryogenic enclosure encloses the two rotors and the armature or only one rotor, with a third cryogenic enclosure around the other rotor without the armature.

Classes IPC  ?

• H02K 55/04 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques du type synchrone avec des enroulements à champ tournant
• B64D 27/24 - Aéronefs caractérisés par le type ou la position des groupes moteurs utilisant la vapeur, l'électricité ou l'énergie de ressorts

Abrégé

The present invention relates to a multi-technique and pluri-decimetric chemical mapping method and device for studying a set of specimens, core samples or indeed a surface, characterized in that the device comprises a control computer, a control unit, a measurement instrument, at least one longitudinal rail (13) extending in a direction referred to as longitudinal direction (X), a support (2) mounted for translational movement on the longitudinal rail in the longitudinal direction, a plate (21) mounted for translational movement on the support in a direction referred to as transverse direction (Y) and perpendicular to the longitudinal direction, a fixing (22) intended for fixing the measurement instrument and mounted for translational movement on the plate in a direction referred to as vertical direction (Z), means (24, 25, 26) for bringing about the translational movement of, respectively, the support, the plate and the fixing, these means being governed by the control unit.

Classes IPC  ?

• G01N 21/01 - Dispositions ou appareils pour faciliter la recherche optique
• G01J 3/02 - Spectrométrie; Spectrophotométrie; Monochromateurs; Mesure de la couleur - Parties constitutives
• G01J 3/44 - Spectrométrie Raman; Spectrométrie par diffusion
• G01N 33/24 - Matériaux de la terre
• G01N 21/64 - Fluorescence; Phosphorescence
• G01N 21/3563 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge pour l'analyse de solides; Préparation des échantillons à cet effet
• G01N 21/65 - Diffusion de Raman
• G01N 23/223 - Recherche ou analyse des matériaux par l'utilisation de rayonnement [ondes ou particules], p.ex. rayons X ou neutrons, non couvertes par les groupes , ou en mesurant l'émission secondaire de matériaux en irradiant l'échantillon avec des rayons X ou des rayons gamma et en mesurant la fluorescence X

Abrégé

The inventors report in the present application the results of applying this innovative analytical approach on three independent EWASs for deriving and validating an epigenome score that exhibited a high diagnostic accuracy for detecting hepatocellular carcinoma (HCC). Indeed, they have performed in silico replication studies on two independent DNA methylome datasets using the 105 CpG probes of the HCC Epigenome Score. All the 13 loci were significantly associated with the HCC phenotype in both replication studies. Consistently, the random effect meta-analysis confirmed the significance of the 13 top loci. The inventors performed dose-response probit regression analysis to assess the association between the HCC Epigenome Score using the 586 samples. The HCC Epigenome score was significantly associated with the risk of HCC with a gradual increase in the risk of HCC according to the increase in the HCC Epigenome Score. Accordingly, the present invention relates to the use of a DNA methylation signature for diagnosing hepatocellular carcinoma in a subject.

Classes IPC  ?

• C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer

Abrégé

The inventors report in the present application the results of applying this innovative analytical approach on three independent EWASs for deriving and validating an epigenome score that exhibited a high diagnostic accuracy for detecting hepatocellular carcinoma (HCC). Indeed, they have performed in silico replication studies on two independent DNA methylome datasets using the 105 CpG probes of the HCC Epigenome Score. All the 13 loci were significantly associated with the HCC phenotype in both replication studies. Consistently, the random effect meta-analysis confirmed the significance of the 13 top loci. The inventors performed dose-response probit regression analysis to assess the association between the HCC Epigenome Score using the 586 samples. The HCC Epigenome score was significantly associated with the risk of HCC with a gradual increase in the risk of HCC according to the increase in the HCC Epigenome Score. Accordingly, the present invention relates to the use of a DNA methylation signature for diagnosing hepatocellular carcinoma in a subject.

Classes IPC  ?

• C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer

Abrégé

Device for chemical looping combustion of a fuel, operating in liquid phase and comprising: - a tank (100) receiving a liquid (101 ) comprising an oxidizing agent and a reducing agent, - an oxidation loop (200) comprising: - a first conduit (201 ), - a first device (205) for injecting a first motor fluid comprising dioxygen, configured for introducing the first motor fluid into the first conduit (201 ), and - a first separating device (208) for separating the first motor fluid from the liquid and for sending the liquid to the tank (100), - a reduction loop (300) comprising: - a second conduit (301 ), - a second device (305) for injecting a second motor fluid comprising a carbon-comprising fuel, configured for introducing the second motor fluid into the second conduit (301 ), and - a second separating device (308), configured for separating the second motor fluid from the liquid.

Classes IPC  ?

• B01J 8/00 - Procédés chimiques ou physiques en général, conduits en présence de fluides et de particules solides; Appareillage pour de tels procédés
• B01J 10/00 - Procédés chimiques généraux faisant réagir un liquide avec des milieux gazeux autrement qu'en présence de particules solides; Appareillage spécialement adapté à cet effet
• C01F 17/00 - Composés des métaux des terres rares
• C01G 3/02 - Oxydes; Hydroxydes
• C01G 19/02 - Oxydes
• C01G 21/02 - Oxydes
• C01G 29/00 - Composés du bismuth
• C01G 31/02 - Oxydes
• C01G 37/02 - Oxydes ou leurs hydrates
• C01G 39/02 - Oxydes; Hydroxydes
• C01G 41/02 - Oxydes; Hydroxydes
• C01G 49/02 - Oxydes; Hydroxydes
• C01G 53/04 - Oxydes; Hydroxydes
• C01B 32/50 - Anhydride carbonique

Abrégé

The invention relates to a method for generating nanoparticles on the surface of a substrate, said method comprising: - a step of providing the substrate made of a material comprising at least one element from columns 4, 5, 13 and 14 of the periodic table, and at least one noble or transition metal; - a step of laser-irradiating the substrate with a pulse duration of between 1 fs and 100 ps, a fluence per pulse of between 0.01 J/cm2 and 100 J/cm2, a wavelength of between 100 nm and 5000 nm, and a number of pulses per point of between 1 and 1000; and - a step of generating at least one nanoparticle on the surface of the substrate, the at least one nanoparticle comprising at least the noble or transition metal, and having a chemical composition different from that of the substrate. The invention also relates to a part comprising such nanoparticles.

Classes IPC  ?

• B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaire; Appareils à cet usage utilisant des radiations électromagnétiques
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites
• B82Y 40/00 - Fabrication ou traitement des nanostructures
• B23K 26/062 - Mise en forme du faisceau laser, p.ex. à l’aide de masques ou de foyers multiples par commande directe du faisceau laser
• B23K 26/082 - Systèmes de balayage, c. à d. des dispositifs comportant un mouvement relatif entre le faisceau laser et la tête du laser
• B23K 26/352 - Travail par rayon laser, p.ex. soudage, découpage ou perçage  pour le traitement de surface
• B23K 26/00 - Travail par rayon laser, p.ex. soudage, découpage ou perçage 
• C21D 10/00 - Modification des propriétés physiques autrement que par traitement thermique ou déformation
• C22F 3/00 - Modification de la structure physique des métaux ou alliages non ferreux par des méthodes physiques particulières, p.ex. traitement par les neutrons
• C23C 14/14 - Matériau métallique, bore ou silicium
• C23C 14/16 - Matériau métallique, bore ou silicium sur des substrats métalliques, en bore ou en silicium
• C23C 14/35 - Pulvérisation cathodique par application d'un champ magnétique, p.ex. pulvérisation au moyen d'un magnétron
• C23C 14/58 - Post-traitement

Abrégé

The invention relates to a method for generating nanoparticles on the surface of a substrate, said method comprising: - a step of providing the substrate made of a material comprising at least one element from columns 4, 5, 13 and 14 of the periodic table, and at least one noble or transition metal; - a step of laser-irradiating the substrate with a pulse duration of between 1 fs and 100 ps, a fluence per pulse of between 0.01 J/cm2 and 100 J/cm2, a wavelength of between 100 nm and 5000 nm, and a number of pulses per point of between 1 and 1000; and - a step of generating at least one nanoparticle on the surface of the substrate, the at least one nanoparticle comprising at least the noble or transition metal, and having a chemical composition different from that of the substrate. The invention also relates to a part comprising such nanoparticles.

Classes IPC  ?

• C23C 14/14 - Matériau métallique, bore ou silicium
• B01J 19/12 - Procédés utilisant l'application directe de l'énergie ondulatoire ou électrique, ou un rayonnement particulaire; Appareils à cet usage utilisant des radiations électromagnétiques
• B23K 26/00 - Travail par rayon laser, p.ex. soudage, découpage ou perçage 
• B23K 26/062 - Mise en forme du faisceau laser, p.ex. à l’aide de masques ou de foyers multiples par commande directe du faisceau laser
• B23K 26/082 - Systèmes de balayage, c. à d. des dispositifs comportant un mouvement relatif entre le faisceau laser et la tête du laser
• B23K 26/352 - Travail par rayon laser, p.ex. soudage, découpage ou perçage  pour le traitement de surface
• C23C 14/35 - Pulvérisation cathodique par application d'un champ magnétique, p.ex. pulvérisation au moyen d'un magnétron
• C23C 14/58 - Post-traitement
• C22F 3/00 - Modification de la structure physique des métaux ou alliages non ferreux par des méthodes physiques particulières, p.ex. traitement par les neutrons
• B82Y 40/00 - Fabrication ou traitement des nanostructures
• B82Y 30/00 - Nanotechnologie pour matériaux ou science des surfaces, p.ex. nanocomposites
• C21D 10/00 - Modification des propriétés physiques autrement que par traitement thermique ou déformation
• C23C 14/16 - Matériau métallique, bore ou silicium sur des substrats métalliques, en bore ou en silicium

Abrégé

The invention relates to a method for manufacturing a porous adsorbent coating, comprising the steps of: - obtaining a homogeneous mixture comprising water, mesoporous particles in which the grains have a diameter of less than 800 ?m and a reinforcement; - covering all or part of a component to be coated with a layer of homogeneous mixture; and - compressing the layer of mixture onto the component to be coated under a pressure of more than 10 bar.

Classes IPC  ?

• B01J 20/10 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant de la silice ou un silicate
• B01J 20/24 - Composés macromoléculaires d'origine naturelle, p.ex. acides humiques ou leurs dérivés
• B01J 20/32 - Imprégnation ou revêtement
• F25B 17/08 - Machines, installations ou systèmes à sorption, à marche discontinue, p.ex. à absorption ou à adsorption l'absorbant ou l'adsorbant étant un solide, p.ex. du sel
• F25B 37/00 - Absorbeurs; Adsorbeurs

Abrégé

The present invention relates to an ocular delivery system useful for the treatment of glaucoma. Especially, the invention provides a mucoadhesive ocular insert comprising a matrix of preactivated thiomer of hyaluronic acid and one or more anti-glaucoma drug.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/5377 - 1,4-Oxazines, p.ex. morpholine non condensées et contenant d'autres hétérocycles, p.ex. timolol
• A61K 31/5575 - Eicosanoïdes, p.ex. leucotriènes ayant un cycle cyclopentane, p.ex. prostaglandine E2, prostaglandine F2-alpha
• A61K 47/36 - Polysaccharides; Leurs dérivés, p.ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine
• A61K 47/50 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament
• A61K 9/70 - Bases pour bande, feuille ou filament

Abrégé

The present invention relates to an ocular delivery system useful for the treatment of glaucoma. Especially, the invention provides a mucoadhesive ocular insert comprising a matrix of preactivated thiomer of hyaluronic acid and one or more anti-glaucoma drug.

Classes IPC  ?

• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 47/50 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament
• A61K 9/70 - Bases pour bande, feuille ou filament
• A61K 31/5377 - 1,4-Oxazines, p.ex. morpholine non condensées et contenant d'autres hétérocycles, p.ex. timolol
• A61K 31/5575 - Eicosanoïdes, p.ex. leucotriènes ayant un cycle cyclopentane, p.ex. prostaglandine E2, prostaglandine F2-alpha
• A61K 47/36 - Polysaccharides; Leurs dérivés, p.ex. gommes, amidon, alginate, dextrine, acide hyaluronique, chitosane, inuline, agar-agar ou pectine

Abrégé

The invention relates to a method for manufacturing a porous adsorbent coating, comprising the steps of: - obtaining a homogeneous mixture comprising water, mesoporous particles in which the grains have a diameter of less than 800 μm and a reinforcement; - covering all or part of a component to be coated with a layer of homogeneous mixture; and - compressing the layer of mixture onto the component to be coated under a pressure of more than 10 bar.

Classes IPC  ?

• B01J 20/10 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant de la silice ou un silicate
• B01J 20/24 - Composés macromoléculaires d'origine naturelle, p.ex. acides humiques ou leurs dérivés
• B01J 20/32 - Imprégnation ou revêtement
• F25B 17/08 - Machines, installations ou systèmes à sorption, à marche discontinue, p.ex. à absorption ou à adsorption l'absorbant ou l'adsorbant étant un solide, p.ex. du sel
• F25B 37/00 - Absorbeurs; Adsorbeurs

Abrégé

The invention relates to a method for constructing a mosaic image from a sequence S of images of a hollow organ, said sequence S of images originating from an endoscope inserted into the hollow organ, said method being implemented by an electronic device comprising a processor and a memory. Such a method comprises: - a step of selecting images, from said sequence S of images, providing a subset of images Sc and a reference image Icrefref among this subset of images Sc; - a step of determining geometric links H between the previously determined reference image and the images of the subset of images Sc; and - a step of constructing the mosaic image from the reference image Icrefref, at least some of the images of the subset of images Sc and the geometric links H of these images of the subset of images Sc.

Classes IPC  ?

• G06T 3/40 - Changement d'échelle d'une image entière ou d'une partie d'image

Abrégé

The present invention relates to a superconducting pellet for a superconducting electrical machine, the superconducting pellet having a circumferential wall, the circumferential wall having: a first border, a second border opposite the first border, an inner face connecting the first border to the second border, an outer face opposite the inner face, and a cavity formed between the first border and the second border and defined by the inner face, and an additional wall which covers the first border or is flush with the first border so as to at least partially cover the cavity, or extends from the inner face at a distance from the first border and the second border so as to divide the cavity into two portions.

Classes IPC  ?

• H02K 55/02 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques du type synchrone
• H02K 15/02 - Procédés ou appareils spécialement adaptés à la fabrication, l'assemblage, l'entretien ou la réparation des machines dynamo-électriques des corps statoriques ou rotoriques
• B64D 27/24 - Aéronefs caractérisés par le type ou la position des groupes moteurs utilisant la vapeur, l'électricité ou l'énergie de ressorts

Abrégé

The invention relates to a respirator (1) comprising: - a cylinder (2) defining an internal space that accommodates a sealingly slidably mounted piston (3), the piston (3) being capable of moving along a central endless screw (6) axially extending into the cylinder (2), the cylinder (2) comprising an air chamber (33) having a variable volume, the movement of the piston (3) producing a variation in the volume and pressure in the chamber; - a unidirectional valve (5) connected to the outlet of the chamber through which compressed air is expelled due to the movement of the piston (3), the valve (5) being capable of being connected to a mask; - a monitoring and control unit (4) that controls the movement of the piston (3) within the cylinder (2). Said respirator is characterised in that the inner section of the cylinder (2) is oval, since the piston (3) is oval.

Classes IPC  ?

• A61M 16/00 - Dispositifs pour agir sur le système respiratoire des patients par un traitement au gaz, p.ex. bouche-à-bouche; Tubes trachéaux
• F04B 9/04 - "Machines" ou pompes à piston caractérisées par les moyens entraînants ou entraînés liés à leurs organes de travail les moyens étant mécaniques constitués par des cames, des excentriques ou des mécanismes à téton et rainure guide
• F04B 39/04 - Mesures pour éviter que le lubrifiant ne contamine le fluide pompé
• F04B 53/14 - Pistons, tiges de piston ou liaisons piston-tige

Abrégé

A superconducting flux barrier electric motor, including at least one induced element and at least one conductor, one of the armature or the inductor housing at least one rotor and at least one superconducting induction coil, and the other including at least one arrangement of the electromagnetic coils coaxial with the superconducting induction coil the rotor comprising superconducting pellets mounted radially inside the superconducting coil on an axis of rotation of the motor, where the electromagnetic coils are made of superconducting material and the induced element and the inductor are arranged in an assembly forming a cooling chamber provided with specific cooling means for the superconducting elements of the induced element and the inductor.

Classes IPC  ?

• H02K 55/00 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques
• H01F 6/06 - Bobines, p.ex. dispositions pour l'enroulement, l'isolation, les enveloppes ou les bornes des bobines
• H02K 9/00 - Dispositions de refroidissement ou de ventilation

Abrégé

A process for the deposition of a coating on at least a part of a metallic substrate, a) mixing a liquid and a powder having particles of a metallic material to be deposited and particles of a pickling agent, so as to prepare a suspension, b) application of the suspension prepared in step a) to at least a part of the surfaces of the metallic substrate, so as to obtain a substrate-suspension assembly, c) carrying out a heat treatment of the assembly which includes heating at a first temperature of at least 500° C. and heating at a second temperature greater than the first temperature, and d) recovery of a substrate coated, at least in part, with a coating, the pickling agent being a halogenated compound and the suspension having from 10% to 60% of the pickling agent, with respect to the total weight of the powder.

Classes IPC  ?

• C23C 24/08 - Revêtement à partir de poudres inorganiques en utilisant la chaleur ou une pression et la chaleur

Abrégé

The invention relates to a compound of formula (I) and to the pharmaceutically acceptable salts thereof. The invention also relates to the use of said compound of formula (I) in the treatment of cancer, particularly by photodynamic therapy.

Classes IPC  ?

• A61K 41/00 - Préparations médicinales obtenues par traitement de substances par énergie ondulatoire ou par rayonnement corpusculaire
• A61K 49/00 - Préparations pour examen in vivo
• A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
• A61P 35/00 - Agents anticancéreux

Abrégé

The present invention relates to copper nanoclusters, characterised in that they: - are covered on their surface by a mixed layer comprising histidine (His), acetate ions (Ac) and optionally ascorbate ions (Asc), - are spherically shaped, - have a hydrodynamic diameter ranging from 0.6 to 2.0 nm, and preferably of 1.3 nm, - have a metal core diameter ranging from 0.5 to 1.5 nm, and preferably of 1.0 nm, - have a stability over time ranging from 5 to 12 weeks when the nanoclusters are in solution, - have a stability over time of at least 12 months, and preferably 12 to 18 months when the nanoclusters are in dry form, - have spectrophotometric properties, with a shoulder peak on the UV-visible spectrum at 325 ± 10 nm and a fluorescence spectrum with excitation wavelengths ranging from 365 to 395 nm and emission wavelengths ranging from 445 to 475 nm, the copper nanoclusters being denoted by the formula "CuNC@HisAc" or "CuNC@HisAcAsc". The invention further relates to a method for preparing copper nanoclusters. The invention further relates to copper nanoclusters for use in the treatment of copper deficiency-related diseases and, in particular, Menkes disease.

Classes IPC  ?

• A61K 9/51 - Nanocapsules
• A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
• A61K 33/34 - Cuivre; Ses composés
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

The present invention relates to copper nanoclusters, characterised in that they: - are covered on their surface by a mixed layer comprising histidine (His), acetate ions (Ac) and optionally ascorbate ions (Asc), - are spherically shaped, - have a hydrodynamic diameter ranging from 0.6 to 2.0 nm, and preferably of 1.3 nm, - have a metal core diameter ranging from 0.5 to 1.5 nm, and preferably of 1.0 nm, - have a stability over time ranging from 5 to 12 weeks when the nanoclusters are in solution, - have a stability over time of at least 12 months, and preferably 12 to 18 months when the nanoclusters are in dry form, - have spectrophotometric properties, with a shoulder peak on the UV-visible spectrum at 325 ± 10 nm and a fluorescence spectrum with excitation wavelengths ranging from 365 to 395 nm and emission wavelengths ranging from 445 to 475 nm, the copper nanoclusters being denoted by the formula "CuNC@HisAc" or "CuNC@HisAcAsc". The invention further relates to a method for preparing copper nanoclusters. The invention further relates to copper nanoclusters for use in the treatment of copper deficiency-related diseases and, in particular, Menkes disease.

Classes IPC  ?

• A61K 9/51 - Nanocapsules
• A61K 33/34 - Cuivre; Ses composés
• A61K 47/54 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un composé organique
• A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
• A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence

Abrégé

The invention relates to a facility for detecting at least one characteristic parameter of a medium (M), this detection facility (1) comprising means (3) for illuminating the medium (M) with a visible polychromatic light, means (4) for exciting the medium (M) with a visible-light or infrared monochromatic radiation, first means (5) for collecting and conveying at least a first electromagnetic radiation emitted by the medium (M), second means (6) for collecting and conveying at least a second electromagnetic radiation emitted by the medium (M), at least one visible-band spectrometer (7) for obtaining at least one visible-band spectrum of the medium (M) from said at least a first electromagnetic radiation, at least one Raman spectrometer (8) for obtaining at least one Raman spectrum of the medium (M) from said at least a second electromagnetic radiation, and means (9) for detecting said at least one characteristic parameter from said at least one visible-band spectrum and from said at least one Raman spectrum of the medium (M).

Classes IPC  ?

• G01N 21/65 - Diffusion de Raman

Abrégé

The invention relates to a facility for detecting at least one characteristic parameter of a medium (M), this detection facility (1) comprising means (3) for illuminating the medium (M) with a visible polychromatic light, means (4) for exciting the medium (M) with a visible-light or infrared monochromatic radiation, first means (5) for collecting and conveying at least a first electromagnetic radiation emitted by the medium (M), second means (6) for collecting and conveying at least a second electromagnetic radiation emitted by the medium (M), at least one visible-band spectrometer (7) for obtaining at least one visible-band spectrum of the medium (M) from said at least a first electromagnetic radiation, at least one Raman spectrometer (8) for obtaining at least one Raman spectrum of the medium (M) from said at least a second electromagnetic radiation, and means (9) for detecting said at least one characteristic parameter from said at least one visible-band spectrum and from said at least one Raman spectrum of the medium (M).

Classes IPC  ?

• G01N 21/65 - Diffusion de Raman
• G01N 21/31 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique
• G01N 21/85 - Analyse des fluides ou solides granulés en mouvement

Abrégé

00 (x, y, z), the platform being mobile in the directions (x, y, z), the platform being mobile in the directions (x, y, z) and being connected to the volume (V) by N cables, where N is greater than or equal to 3, the cables being fixed at one end at anchoring points on the platform side and at the other end at anchoring points on the environment side, the positioning device comprising, for each cable, a fixed actuator positioned between one of the ends of the cable and the adjacent anchoring point and making it possible to control the length of a given cable, the platform comprising, for each cable, a mobile actuator for controlling the position of the anchoring point on the platform side with respect to the platform.

Classes IPC  ?

• B25J 9/00 - Manipulateurs à commande programmée

Abrégé

The invention relates to a concrete floor (10) comprising at least one beam (12) having a main axis (X), a concrete slab (24) which is cast so as to rest on an upper face (14) of the beam (12), a metal reinforcement (30) set in the slab (24), the beam (12) being connected to the concrete slab (24) by means of at least one inserted connecting element which is fastened to the beam (12) and at least a portion of which is set in the concrete slab (24), characterized in that the beam (12) and the connecting element are made of wood.

Classes IPC  ?

• E04B 5/43 - Structures de planchers de conception particulière; Caractéristiques relatives à la stabilité élastique; Structures de planchers spécialement conçus pour reposer uniquement sur des colonnes, p.ex. planchers-champignons
• E04B 5/12 - Structures portantes de planchers, formées essentiellement d'éléments préfabriqués comportant des poutres de bois
• E04B 5/23 - Structures de planchers partiellement formées sur place avec des nervures de renforcement ou autres conformations semblables à des poutres totalement ou partiellement préfabriquées
• E04B 5/26 - Structures de planchers partiellement formées sur place avec des nervures de renforcement ou autres conformations semblables à des poutres totalement ou partiellement préfabriquées avec des éléments de remplissage entre les poutres
• E04B 5/28 - Planchers à caissons

Abrégé

The invention relates to a shot-processing device which comprises a memory (10), a detector (20), a preparer (30), a combiner (40), an estimator (50) and a selector (60). The memory (10) is arranged to receive, on the one hand, scene data (12) that comprise three-dimensional object pairs each associating an object identifier, and ellipsoid data which define an ellipsoid and its orientation and a position of its centre in a common frame of reference and, on the other hand, shot data (14) defining a two-dimensional image of the scene associated with the scene data (12), from a viewpoint corresponding to a desired pose. The detector (20) is arranged to receive shot data (14) and to return one or more two-dimensional object pairs (22) each comprising an object identifier present in the scene data, and a shot region associated with this object identifier. The preparer (30) is arranged to determine, for at least some of the two-dimensional object pairs (22) from the detector (20), a set of positioning elements (32) whose number is less than or equal to the number of three-dimensional object pairs in the scene data (12) that comprise the object identifier of the two-dimensional object pair (22) in question, each positioning element (32) associating the object identifier and the ellipsoid data of a three-dimensional object pair comprising this object identifier, and ellipse data which define an ellipse approximating the shot region of the two-dimensional object pair in question and its orientation as well as a position of its centre in the two-dimensional image. The combiner (40) is arranged to generate a list of candidates (42) each associating one or more positioning elements (32) and a shot orientation, and/or the combination of at least two positioning elements (32), the positioning elements (32) of a single candidate (42) being taken from separate two-dimensional object pairs (22) and not relating to the same three-dimensional object pair. The estimator (50) is arranged to calculate, for at least one of the candidates, a pose (52) comprising a position and an orientation in the common frame of reference from the ellipse data and the ellipsoid data of the positioning elements, or from the ellipse data and the ellipsoid data of the one or more positioning elements and the shot orientation. The selector (60) is arranged, for at least some of the poses, to project all of the ellipsoid data of the scene data onto the shot data from the pose, to determine a measurement of similarity between each projection of the ellipsoid data and each ellipse defined by a two-dimensional object pair (22) coming from the detector (20), and to calculate a likelihood value by using, for each projection of the ellipsoid data, the largest measurement of similarity determined, and to select the pose that has the highest likelihood value.

Classes IPC  ?

• G06T 7/70 - Détermination de la position ou de l'orientation des objets ou des caméras
• G06V 20/64 - Objets tridimensionnels
• G06T 7/60 - Analyse des attributs géométriques
• G06V 10/74 - Appariement de motifs d’image ou de vidéo; Mesures de proximité dans les espaces de caractéristiques
• G06V 10/22 - Prétraitement de l’image par la sélection d’une région spécifique contenant ou référençant une forme; Localisation ou traitement de régions spécifiques visant à guider la détection ou la reconnaissance

Abrégé

The present invention relates to an implantable device for cardiac assistance by direct compression, characterized in that it comprises: - a base (1) forming a receptacle for receiving the lower part of a heart (9), - a support (2) for fixing the lower part of the heart to the base, - at least one finger (3) extending longitudinally between a free upper first end (35) and a curved lower second end (36) inside the base, the finger being mounted on the base via a first pivot connection (12), - a contact interface (4) mounted adjustably and movably on the free end, - means (5, 6) for actuating the tilting movement of the finger about the pivot connection, - a control unit (10) for controlling the actuating means.

Classes IPC  ?

• A61M 60/191 - Pompes ou dispositifs de pompage implantables, c.-à-d. que le sang est pompé à l’intérieur du corps du patient implantables dans ou sur le cœur, ou autour du cœur agissant mécaniquement sur l’extérieur du cœur natif du patient, p.ex. structures compressives placées autour du cœur
• A61M 60/289 - Dispositifs de circulation mécanique pour assistance de la fonction cardiaque résiduelle par action mécanique sur le cœur natif ou la structure de vaisseaux sanguins du patient, p.ex. dispositifs de compression cardiaque directe
• A61M 60/465 - Pompes pour le sang; Dispositifs pour l'actionnement mécanique de la circulation; Pompes à ballon d’assistance circulatoire - Détails concernant l’entraînement pour des dispositifs d’actionnement circulatoire mécanique
• A61M 60/839 - Pompes pour le sang; Dispositifs pour l'actionnement mécanique de la circulation; Pompes à ballon d’assistance circulatoire - Détails structurels autres que ceux relatifs à l’entraînement de la pompe des dispositifs pour l'actionnement de la circulation mécanique
• A61M 60/873 - Dispositifs d’alimentation en énergie; Convertisseurs à cet effet spécialement adaptés au transfert d’énergie sans fil ou transcutané, p.ex. à la charge par induction
• A61M 60/863 - Anneaux sommitaux
• A61M 60/508 - Moyens de commande électroniques, p.ex. pour la régulation par rétroaction
• A61M 60/47 - Pompes pour le sang; Dispositifs pour l'actionnement mécanique de la circulation; Pompes à ballon d’assistance circulatoire - Détails concernant l’entraînement pour des dispositifs d’actionnement circulatoire mécanique la force agissant sur les moyens d’actionnement étant mécanique, p.ex. éléments à entraînement mécanique de pincement d’un vaisseau sanguin
• A61M 60/523 - Régulation par des données du patient en temps réel par les données d’écoulement du sang, p.ex. en provenance de transducteurs de mesure de l’écoulement du sang
• A61M 60/515 - Régulation par des données du patient en temps réel
• A61M 60/531 - Régulation par des données du patient en temps réel par des données de tension artérielle, p.ex. provenant de capteurs de tension
• A61M 60/562 - Moyens de commande électroniques, p.ex. pour la régulation par rétroaction pour pulser l’écoulement du sang dans les pompes pour le sang qui ne créent intrinsèquement pas un écoulement pulsé

Abrégé

The present invention is in the field of metal matrix polymer derived ceramic composites, processes of production and uses thereof. In particular, the invention concerns metal matrix polymer derived ceramic composites comprising ceramic nanoparticles, processes of production comprising a step of severe plastic deformation, and uses thereof.

Classes IPC  ?

• C22C 1/05 - Mélanges de poudre métallique et de poudre non métallique
• C22C 32/00 - Alliages non ferreux contenant entre 5 et 50% en poids d'oxydes, de carbures, de borures, de nitrures, de siliciures ou d'autres composés métalliques, p.ex. oxynitrures, sulfures, qu'ils soient soient ajoutés comme tels ou formés in situ

Abrégé

The invention relates to an assembly of leaves (14, 16) for producing a structure of a wall or a lattice beam, the assembly comprising: - a first leaf (16) oriented along an axis (X) and comprising a front face (16a); - a second leaf (14) oriented along an axis (Y) and comprising a rear face (14b); - a contact region (18) of the front face (16a) of the first leaf (16) bearing in planar fashion against a complementary contact region (18) of the rear face (14b) of the second leaf (14); characterized in that it comprises two immobilizing plates (30), each of which is attached and fastened to the contact region (18) of an associated leaf (14, 16), the two immobilizing plates (30) comprising identical nesting patterns (36) that are designed to allow the two immobilizing plates (30) to nest.

Classes IPC  ?

• E04B 1/10 - Structures constituées principalement d'éléments porteurs en forme de blocs ou de dalles les éléments étant en bois
• E04C 2/12 - Eléments de construction de relativement faible épaisseur pour la construction de parties de bâtiments, p.ex. matériaux en feuilles, dalles ou panneaux caractérisés par des matériaux spécifiés en produits mousse en bois plein
• E04C 2/42 - Grilles; Panneaux grillagés
• E04B 2/00 - Murs, p.ex. cloisons, pour bâtiments; Structure des murs en ce qui concerne l'isolation; Assemblages spécifiques pour les murs
• E04C 3/17 - Poutrelles; Solives, fermes ou structures analogues à des fermes, p.ex. préfabriquées; Linteaux; Traverses en bois, p.ex. avec armatures ou tirants à bords supérieurs et inférieurs non parallèles, p.ex. fermes de toit
• E04B 1/26 - Structures comportant des éléments porteurs allongés, p.ex. colonnes, poutres, ossatures les pièces porteuses étant en bois

Abrégé

The present invention concerns the use of a device comprising a porous electrode and an electrically insulating porous layer to remove oxygen in contact with a working electrode. The present invention also concerns the use of said device in contact to said working electrode to detect and/or quantify an analyte in presence of oxygen.

Classes IPC  ?

• G01N 27/404 - Cellules avec l'anode, la cathode et l'électrolyte de la cellule du même côté d'une membrane perméable qui les sépare du fluide de l'échantillon
• G01N 27/327 - Electrodes biochimiques

Abrégé

The present invention relates to an implantable medical device comprising a layer consisting of or comprising zirconia, and to a method for the preparation thereof.

Classes IPC  ?

• A61C 8/00 - Moyens destinés à être fixés à l'os de la mâchoire pour consolider les dents naturelles ou pour y assujettir des prothèses dentaires; Implants dentaires; Outils pour l'implantation
• A61C 13/00 - Prothèses dentaires; Leurs procédés de fabrication
• A61L 27/10 - Céramiques ou verres
• A61L 27/30 - Matériaux inorganiques
• A61L 27/50 - Matériaux caractérisés par leur fonction ou leurs propriétés physiques

Abrégé

The invention relates to a handle (22) for a shaft (3), of the oar shaft type, comprising a hollow body (1) extending longitudinally along an axis X and having: - an outer wall (4) for handling; - an inner wall (5) defining a cylindrical cavity (6), the inner wall (5) being able to come into contact with a shaft (3) and comprising distortion means for mounting on the shaft (3). These distortion means consist of helical grooves (10) made in the inner wall (5) and extending from one end to the other of the body (1).

Classes IPC  ?

• B63H 16/04 - Avirons; Godilles; Pagaies; Perches
• A63B 22/00 - Appareils d'exercice spécialement adaptés à l'entraînement du système cardio-vasculaire, pour exercer l'agilité ou la coordination des mouvements
• A63B 60/06 - Poignées
• B25G 1/10 - Fabrication des manches caractérisés par le matériau ou la forme
• B25G 3/30 - Dispositifs de verrouillage ou de blocage comprenant des douilles ou soies filetées
• A63B 69/06 - Appareils d'entraînement ou appareils destinés à des sports particuliers pour canotage ou aviron

Abrégé

A device for radioactivity counting and characterization for a solution. The device includes a container having at least two recesses, a first recess for receiving a vial and a second recess for receiving a radioactivity sensor, a radioactivity sensor having a semiconductor sensor presenting a cone of detection directed to the first recess of the container for receiving a vial, a removable closure element, an armored cover around the container and its upper face, the upper face of the armored cover having an opening for introducing the vial into the container and a plate for supporting the device.

Classes IPC  ?

• G01T 7/02 - Moyens de collection pour recevoir ou conserver des échantillons à examiner
• G01T 1/24 - Mesure de l'intensité de radiation avec des détecteurs à semi-conducteurs
• G21F 5/015 - Récipients blindés portatifs ou transportables pour le stockage de sources radioactives, p.ex. supports de sources pour unités d'irradiation; Récipients pour radio-isotopes
• G21F 5/12 - Dispositifs obturateurs pour récipients; Dispositions pour leur étanchéité

Abrégé

The present invention relates to a superconducting electric machine (1), for example an axial or radial flow electric machine, comprising an inductor (3) having superconducting pellets (7) circumferentially distributed about an axis (X) of the electric machine (1), and a flow barrier (12) comprising a superconducting material, said flow barrier (12) being centered on the axis of rotation (X) and extending radially inside the superconducting pellets (7).

Classes IPC  ?

• H02K 55/00 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques

Abrégé

The present invention relates to a superconducting electric machine (1) comprising an inductor (3) having: - superconducting pellets (7) circumferentially distributed about an axis (X) of the electric machine (1), - an armature (2) comprising coils (5), each coil (5) having a circumferential radially inner edge (10) and a circumferential radially outer edge (9), and - at least one flow barrier (12, 12') extending circumferentially with respect to the axis (X), each flow barrier (12) extending between the superconducting pellets (7) and the armature (2) so as to at least partially cover at least one of the radially outer edge (9) and the radially inner edge (10) of all or part of the coils (5) of the armature (2).

Classes IPC  ?

• H02K 55/00 - Machines dynamo-électriques comportant des enroulements qui fonctionnent à des températures cryogéniques
• H01F 6/06 - Bobines, p.ex. dispositions pour l'enroulement, l'isolation, les enveloppes ou les bornes des bobines

Abrégé

The present invention relates to a composite material with a graded or homogeneous matrix, the production method thereof, and the uses of same.

Classes IPC  ?

• B22D 19/16 - Coulée dans, sur, ou autour d'objets formant partie intégrante du produit final pour fabriquer des moulages composites à partir de métaux différents, p.ex. pour fabriquer des cylindres de laminoirs
• C22C 1/08 - Alliages poreux avec pores ouverts ou fermés
• B33Y 10/00 - Procédés de fabrication additive
• B29C 70/00 - Façonnage de matières composites, c. à d. de matières plastiques comprenant des renforcements, des matières de remplissage ou des parties préformées, p.ex. des inserts

Abrégé

Provided is a technology for monitoring the behavior of a control system with high accuracy. One embodiment of the present invention pertains to a monitoring device that includes: an acquisition unit that acquires an observation value regarding the behavior of a control system, the observation value being sampled while the system is being operated; and an evaluation unit that determines a fluctuation range of the observation value with respect to the control system behavior, and that evaluates whether the fluctuation range of the observation value satisfies specifications regarding the observation value.

Classes IPC  ?

• G06F 11/07 - Réaction à l'apparition d'un défaut, p.ex. tolérance de certains défauts
• G05B 23/02 - Test ou contrôle électrique
• G16Y 40/20 - Analyse; Diagnostic

Abrégé

Non-magnetic part comprising an austenitic alloy, the austenitic alloy comprising between 50 and 85 wt % of iron, one or more gammagene elements the weight percentage or the total weight percentages of which amount to between 15 and 35 wt %, and less than 2 wt % of nitrogen. The austenitic alloy has a crystallographic structure comprising a predominantly cubic crystal structure and the presence of a hexagonal crystal structure. The magnetic part comprises a hardness gradient in the direction extending radially from the surface of the at least one portion of the non-magnetic part to the inside of the non-magnetic part, the hardness gradient having a value greater than or equal to 100 HV.

Classes IPC  ?

• C21D 1/26 - Méthodes de recuit
• C21D 7/04 - Modification des propriétés physiques du fer ou de l'acier par déformation par travail à froid de la surface
• C21D 9/00 - Traitement thermique, p.ex. recuit, durcissement, trempe ou revenu, adapté à des objets particuliers; Fours à cet effet
• C22C 38/00 - Alliages ferreux, p.ex. aciers alliés
• C22C 38/04 - Alliages ferreux, p.ex. aciers alliés contenant du manganèse
• C21D 1/74 - Procédés de traitement en gaz neutre, en atmosphère contrôlée, sous vide ou dans des matières pulvérulentes
• C22C 38/02 - Alliages ferreux, p.ex. aciers alliés contenant du silicium 
• C22C 19/00 - Alliages à base de nickel ou de cobalt, seuls ou ensemble
• C22C 19/05 - Alliages à base de nickel ou de cobalt, seuls ou ensemble à base de nickel avec du chrome
• C22C 30/00 - Alliages contenant moins de 50% en poids de chaque constituant
• C22C 38/28 - Alliages ferreux, p.ex. aciers alliés contenant du chrome et du titane ou du zirconium
• C22C 38/30 - Alliages ferreux, p.ex. aciers alliés contenant du chrome et du cobalt
• C22C 38/34 - Alliages ferreux, p.ex. aciers alliés contenant du chrome et plus de 1,5% en poids de silicium
• C22C 38/38 - Alliages ferreux, p.ex. aciers alliés contenant du chrome et plus de 1,5% en poids de manganèse
• C22C 38/60 - Alliages ferreux, p.ex. aciers alliés contenant du plomb, du sélénium, du tellure, de l'antimoine, ou plus de 0,04% en poids de soufre
• C22C 38/22 - Alliages ferreux, p.ex. aciers alliés contenant du chrome et du molybdène ou du tungstène
• C22C 38/26 - Alliages ferreux, p.ex. aciers alliés contenant du chrome et du niobium ou du tantale

Abrégé

The invention relates to a process for producing a sunflower protein isolate, said process comprising the following steps: (a) providing a sunflower seed press cake, preferably a sunflower seed cold press cake; (b) mixing said sunflower seed press cake with an aqueous NaCI solution at a pH ranging from 3 to 4.5, in order to solubilize proteins present in said sunflower seed press cake and to thus obtain a solubilised protein solution, wherein said aqueous NaCI solution has a NaCI concentration ranging from 0.2 to 0.6 mol·L−1; (c) separating said solubilised protein solution from solids therein; (d) subjecting said solubilised protein solution obtained in step c) to one or several membrane filtration(s) to obtain a protein isolate, and optionally drying said protein isolate to obtain a dry sunflower protein isolate. The invention also relates to a sunflower protein isolate and its use and product which incorporate.

Classes IPC  ?

• A23J 1/14 - Préparation des compositions à base de protéines pour l'alimentation; Ouverture des œufs par grandes quantités et séparation du jaune du blanc à partir des tourteaux ou des graines oléagineuses
• B01D 61/14 - Ultrafiltration; Microfiltration
• A23L 2/66 - Protéines
• B01D 11/02 - Extraction par solvants de solides

Abrégé

Electrode (1) comprising a storage film (2). The storage film (2) comprises a layer (3) of a support material comprising at least one inclusion (4) in which a compound of interest is stored and a wall (5) of permeable sealing material sealing the at least one inclusion. The storage film (2) further comprises a porous layer (6) covering, at least in part, the wall of sealing material, at least a portion of a surface of the porous layer constituting an active surface of the electrode.

Classes IPC  ?

• H01M 8/16 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Éléments à combustible; Leur fabrication Éléments à combustible biochimique, c. à d. éléments dans lesquels des micro-organismes agissent comme catalyseurs
• A61K 9/51 - Nanocapsules
• B01J 13/14 - Polymérisation, réticulation
• C12N 11/02 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique
• G01N 27/30 - Composants de cellules électrolytiques Électrodes, p.ex. électrodes pour tests; Demi-cellules
• H01M 4/86 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes inertes ayant une activité catalytique, p.ex. pour piles à combustible
• H01M 4/88 - Procédés de fabrication

Abrégé

The present invention relates to the use of a multimeric protein of the peroxiredoxin family as a scaffold protein, characterized in that one or more proteins(s) of interest are linked to one or two N- and C-terminal end(s) of one or more monomers(s) of the peroxiredoxin, said peroxiredoxin having no redox activity.

Classes IPC  ?

• C12N 9/00 - Enzymes, p.ex. ligases (6.); Proenzymes; Compositions les contenant; Procédés pour préparer, activer, inhiber, séparer ou purifier des enzymes

Abrégé

The present invention relates to an isolated double stranded DNA polynucleotide that forms triplex with sequence 5'-GGUGGCAGCAAGAGAAAAAUGAGGAAGAAGCAAAAGCGGAAA-3' (SEQ ID NO : 1) of the long non-coding RNA ANRIL (Antisense Non-coding RNA in the INK4 Locus). It also relates to a vector comprising the double stranded DNA polynucleotide, and to a pharmaceutical composition comprising the double stranded DNA polynucleotide or the vector. The present invention relates as well to the isolated double stranded DNA polynucleotide for use in the treatment of myocardial infarction, aneurysms, stenosis, myocardial infarction, aneurysms, cancers, eye diseases or type 2 diabetes.

Classes IPC  ?

• C12N 15/11 - Fragments d'ADN ou d'ARN; Leurs formes modifiées
• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p.ex. oligonucléotides anti-sens

Abrégé

The present invention relates to an isolated double stranded DNA polynucleotide that forms triplex with sequence 5'-GGUGGCAGCAAGAGAAAAAUGAGGAAGAAGCAAAAGCGGAAA-3' (SEQ ID NO : 1) of the long non-coding RNA ANRIL (Antisense Non-coding RNA in the INK4 Locus). It also relates to a vector comprising the double stranded DNA polynucleotide, and to a pharmaceutical composition comprising the double stranded DNA polynucleotide or the vector. The present invention relates as well to the isolated double stranded DNA polynucleotide for use in the treatment of myocardial infarction, aneurysms, stenosis, myocardial infarction, aneurysms, cancers, eye diseases or type 2 diabetes.

Classes IPC  ?

• C12N 15/11 - Fragments d'ADN ou d'ARN; Leurs formes modifiées
• C12N 15/113 - Acides nucléiques non codants modulant l'expression des gènes, p.ex. oligonucléotides anti-sens

Abrégé

A fluidic system for loading a therapeutic or imaging agent into the lumen of extracellular vesicles from producer cells, including at least one container, a liquid medium contained in the container, producer cells, a liquid medium stirrer and a device for controlling the speed of the stirrer suitable for the growth of the producer cells, wherein it also includes a device for controlling the speed of the stirrer and the stirrer, of which the shape and dimensions of the container are suitable for generating a turbulent flow of the liquid medium in the container for exerting shear stresses on the producer cells in order to carry out the loading of a therapeutic or imaging agent into the lumen of the extracellular vesicles produced simultaneously by the fluidic system.

Classes IPC  ?

• C12M 1/06 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'introduction de gaz avec agitateur, p.ex. avec agitateur à turbine
• C12N 15/86 - Vecteurs viraux
• C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p.ex. composés antiphlogistiques et pour le cœur 
• C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p.ex. par des compteurs de colonies
• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie

Abrégé

The invention proposes a device for three-dimensional printing of a glass object, by applying and solidifying successive layers of a material constituting the glass, in locations corresponding to the section of the object to be produced in the corresponding layer, by means of a laser producing a beam whose wavelength allows the direct fusion in the core of the material. The invention proposes a device for three-dimensional printing of a glass object, by applying and solidifying successive layers of a material constituting the glass, in locations corresponding to the section of the object to be produced in the corresponding layer, by means of a laser producing a beam whose wavelength allows the direct fusion in the core of the material. The device comprises: means for supplying the material to a support on which the successive layers are formed; means for thermal regulation of the successive layers for holding their temperature during the production of the object and for cooling them after the production of the object; a central unit controlling the laser. The invention proposes a device for three-dimensional printing of a glass object, by applying and solidifying successive layers of a material constituting the glass, in locations corresponding to the section of the object to be produced in the corresponding layer, by means of a laser producing a beam whose wavelength allows the direct fusion in the core of the material. The device comprises: means for supplying the material to a support on which the successive layers are formed; means for thermal regulation of the successive layers for holding their temperature during the production of the object and for cooling them after the production of the object; a central unit controlling the laser. The printing device comprises means for servo-controlling the power and the speed of the laser in real time.

Classes IPC  ?

• B29C 64/153 - Procédés de fabrication additive n’utilisant que des matériaux solides utilisant des couches de poudre avec jonction sélective, p.ex. par frittage ou fusion laser sélectif
• C03B 19/06 - Autres méthodes de façonnage du verre par frittage
• B23K 26/34 - Soudage au laser pour des finalités autres que l’assemblage
• B29C 64/268 - Agencements pour irradiation par faisceaux d’électrons [FE]

Abrégé

Disclosed is a control device (10) comprising: - an input module (17) arranged to acquire a first state vector (x) expressed in the time domain and to transform the first state vector into a second state vector (X) expressed in the frequency domain; - a corrector module (18) arranged to produce a first control vector (U) expressed in the frequency domain from the second state vector and a gain matrix (K), the gain matrix being a block matrix comprising at least one gain block, each gain block being a Hermitian Toeplitz matrix such that: ϰT= ϰ*; - an output module (19) arranged to transform the first control vector into a second control vector (u) expressed in the time domain and adapted to be used to control the controllable member.

Classes IPC  ?

• H02M 1/44 - Circuits ou dispositions pour corriger les interférences électromagnétiques dans les convertisseurs ou les onduleurs
• H02M 3/157 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu sans transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrode de commande utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs avec commande automatique de la tension ou du courant de sortie, p.ex. régulateurs à commutation avec commande numérique
• H02M 1/00 - APPAREILS POUR LA TRANSFORMATION DE COURANT ALTERNATIF EN COURANT ALTERNATIF, DE COURANT ALTERNATIF EN COURANT CONTINU OU VICE VERSA OU DE COURANT CONTINU EN COURANT CONTINU ET EMPLOYÉS AVEC LES RÉSEAUX DE DISTRIBUTION D'ÉNERGIE OU DES SYSTÈMES D'ALI; TRANSFORMATION D'UNE PUISSANCE D'ENTRÉE EN COURANT CONTINU OU COURANT ALTERNATIF EN UNE PUISSANCE DE SORTIE DE CHOC; LEUR COMMANDE OU RÉGULATION - Détails d'appareils pour transformation

Abrégé

A method for concealing data in an image or a video stream inside a compression chain, being implemented by a computer and including a structuring and processing phase, during which at least one image is structured into blocks including coefficients, a phase of converting and quantifying blocks so as to generate converted and quantified coefficients, with entropic coding intended to code the converted and quantified coefficients. The method includes a step of concealing data, during which bits of the data are concealed by modifying converted and quantified coefficients located in a high frequency zone of at least some of the blocks that relate to the luminance component of the video stream and that are intra-coded. This modification is performed after the quantification but before the entropic coding.

Classes IPC  ?

• H04N 19/467 - Inclusion d’information supplémentaire dans le signal vidéo pendant le processus de compression caractérisée par le caractère invisible de l’information incluse, p.ex. un filigrane
• H04N 19/124 - Quantification
• H04N 19/176 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage adaptatif caractérisés par l’unité de codage, c. à d. la partie structurelle ou sémantique du signal vidéo étant l’objet ou le sujet du codage adaptatif l’unité étant une zone de l'image, p.ex. un objet la zone étant un bloc, p.ex. un macrobloc
• H04N 19/18 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage adaptatif caractérisés par l’unité de codage, c. à d. la partie structurelle ou sémantique du signal vidéo étant l’objet ou le sujet du codage adaptatif l’unité étant un ensemble de coefficients de transformée
• H04N 19/593 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant le codage prédictif mettant en œuvre des techniques de prédiction spatiale
• H04N 19/625 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant un codage par transformée utilisant une transformée en cosinus discrète
• H04N 19/63 - Procédés ou dispositions pour le codage, le décodage, la compression ou la décompression de signaux vidéo numériques utilisant un codage par transformée utilisant une transformée en sous-bandes, p.ex. ondelettes
• H04N 19/91 - Codage entropique, p.ex. codage à longueur variable ou codage arithmétique
• G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
• G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p.ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé

Abrégé

The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5372, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.

Classes IPC  ?

• C05F 11/08 - Engrais organiques comportant l'addition de cultures bactériennes, de mycélium ou similaires
• C05G 5/27 - Dispersions, p.ex. suspensions, émulsions
• C12N 1/20 - Bactéries; Leurs milieux de culture

Abrégé

The present invention relates to the field of crop fertilization, and particularly to a biofertilizing bacterial strain. In particular, the present invention relates to the bacterial strain deposited on Oct. 24, 2018, at the Collection Nationale de Culture de Microorganismes (CNCM), 28 rue du Dr. Roux, 75724 PARIS CEDEX 15, under the Budapest Treaty under number CNCM I-5373, and to the uses of this strain. The invention also relates to a composition comprising the above-mentioned bacterial strain and to a fertilization process comprising the application of this composition to a plant or to a soil.

Classes IPC  ?

• C05F 11/08 - Engrais organiques comportant l'addition de cultures bactériennes, de mycélium ou similaires
• C12N 1/20 - Bactéries; Leurs milieux de culture

Abrégé

A process for preparing a sunflower seed protein isolate and a protein isolate which is obtainable by such process. The process comprises the following steps: mixing a defatted seed meal with an aqueous NaCl solution at a basic pH; separating said solubilised protein solution from solids; diafiltering said solubilised protein solution through an ultrafiltration membrane system using an aqueous NaCl diafiltration NaCl solution and at least 2 diavolumes of said aqueous NaCl diafiltration solution, diafiltering said NaCl-diafiltered protein; concentrating said purified protein solution; and drying said purified protein concentrate to obtain a protein isolate.

Classes IPC  ?

• A23J 1/14 - Préparation des compositions à base de protéines pour l'alimentation; Ouverture des œufs par grandes quantités et séparation du jaune du blanc à partir des tourteaux ou des graines oléagineuses
• B01D 61/14 - Ultrafiltration; Microfiltration
• B01D 61/16 - Prétraitement du courant d'alimentation
• A23L 33/185 - Protéines d’origine végétale
• C07K 14/415 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de végétaux

Abrégé

The present invention relates to a process for treating aqueous effluents from the primary circuit of a nuclear power plant implementing a separation of boric acid using a reverse osmosis membrane, characterized by the fact that it comprises steps consisting of treating the effluents using a multi-stage assembly composed of reverse osmosis modules comprising a membrane with a high boron rejection rate, arranged in parallel and in series, and recycling of the intermediate products to different points in the assembly.

Classes IPC  ?

• B01D 37/00 - Procédés de filtration
• B01D 61/02 - Osmose inverse; Hyperfiltration
• B01D 61/08 - Appareils à cet effet
• B01D 61/12 - Commande ou régulation
• B01D 69/12 - Membranes composites; Membranes ultraminces
• G21F 9/06 - Traitements

Abrégé

Disclosed is the non-therapeutic use, as a DNA-demethylating agent, of at least one organometallic compound including an iron atom bound to two terpyridine groups. Further disclosed are method related to applying such agent as medicine.

Classes IPC  ?

• A61K 31/295 - Composés de métaux du groupe du fer
• A61P 35/02 - Agents anticancéreux spécifiques pour le traitement de la leucémie

Abrégé

The present invention relates to the prediction of drug metabolizing enzymes (DME) inhibitors. Inhibition of DMEs leads to adverse drug-drug interaction, hence predicting inhibition of DMEs by determined molecules is critical for preventing drug toxicity. Inventors elaborated a protocol of integrated in silico protein structure-based and machine learning approach to predict inhibition of DMEs. In particular, the present invention relates to a method for training a model for predicting inhibition of DMEs, comprising a selection of a number of descriptors among an initial set comprising physicochemical descriptors and binding energies on at least one enzyme configuration, and a training of a classification model on a learning database of known inhibitors or non- inhibitors based on the selected descriptors as inputs. This approach successfully predicted inhibition of CYP2C9, CYP2D6, SULT1A1, SULT1A3 and UGT1 A1.

Classes IPC  ?

• G16B 15/30 - Ciblage de médicament à l’aide de données structurelles; Prévision d’amarrage ou de liaison moléculaire
• G16B 40/20 - Analyse de données supervisée

Abrégé

The invention relates to a method and system for assisting learning of endoscopic surgery, in particular endonasal surgery, during exercises each comprising a set of instrument movements of the endoscope (101) and/or of one or more surgical instruments (102), carried out by the operator. The system (1) comprises a hardware simulator (107) including one or more thematic models (100), in particular interchangeable modules (109) on a support head (108). It also comprises a computerised management unit (110) which communicates with the endoscope (101) and/or the instrument (102) and/or the module (109) or model (100). For each exercise, it displays the actions to be performed, and detects various endoscope and/or instrument movements and/or contacts. One module (2) presents targets to be visualised in a framed manner, the display of which is validated by shape recognition in the software. Other modules comprise objects to be dissected or moved, while avoiding obstacles. The prohibited or requested movements of instruments, grippers and/or contacts, are recorded by the software in order to evaluate the exercise.

Classes IPC  ?

• G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p.ex. dispositif en vraie grandeur pour la démonstration pour la médecine
• G09B 23/30 - Modèles anatomiques
• G09B 23/32 - Modèles anatomiques avec des parties mobiles

Abrégé

The invention relates to a method and system for assisting learning of endoscopic surgery, in particular endonasal surgery, during exercises each comprising a set of instrument movements of the endoscope (101) and/or of one or more surgical instruments (102), carried out by the operator. The system (1) comprises a hardware simulator (107) including one or more thematic models (100), in particular interchangeable modules (109) on a support head (108). It also comprises a computerised management unit (110) which communicates with the endoscope (101) and/or the instrument (102) and/or the module (109) or model (100). For each exercise, it displays the actions to be performed, and detects various endoscope and/or instrument movements and/or contacts. One module (2) presents targets to be visualised in a framed manner, the display of which is validated by shape recognition in the software. Other modules comprise objects to be dissected or moved, while avoiding obstacles. The prohibited or requested movements of instruments, grippers and/or contacts, are recorded by the software in order to evaluate the exercise.

Classes IPC  ?

• G09B 23/28 - Modèles à usage scientifique, médical ou mathématique, p.ex. dispositif en vraie grandeur pour la démonstration pour la médecine
• G09B 23/30 - Modèles anatomiques
• G09B 23/32 - Modèles anatomiques avec des parties mobiles

Abrégé

3 molar ratio of between 1 and 15; optionally an ethylenediaminetetraacetic acid-based complexing agent at a content of between 1 and 5% by weight relative to the total weight of the electrolyte at a pH of between 6 and 12; optionally an anionic surfactant at a content of between 1 and 5% by weight relative to the total weight of the electrolyte; optionally NaOH to obtain the appropriate pH; and an aqueous solvent.

Classes IPC  ?

• B23H 3/08 - Milieux d'usinage
• C25F 3/22 - Polissage des métaux lourds

Abrégé

The present invention relates to the use of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as a marker in a method for identifying a subject suffering from a disease caused by a coronavirus such as COVID-19 at risk of having or developing a severe form and/or a complication or at risk of death, in a method for assessing the severity of a disease caused by a coronavirus such as COVID-19, and in a method for monitoring a subject suffering from a disease caused by a coronavirus such as COVID-19.

Classes IPC  ?

• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus

Abrégé

The present invention relates to the use of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as a marker in a method for identifying a subject suffering from a disease caused by a coronavirus such as COVID-19 at risk of having or developing a severe form and/or a complication or at risk of death, in a method for assessing the severity of a disease caused by a coronavirus such as COVID-19, and in a method for monitoring a subject suffering from a disease caused by a coronavirus such as COVID-19.

Classes IPC  ?

• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus