The present invention resides in a multichannel head of a pipetting device for aspirating and dispensing liquid via a plurality of pipetting tips. The multichannel head comprises a connector block (110) having an array of m*n connectors (120), whereby each connector comprises an internal passageway (125) that is fluidically connectable to a pipetting tip, and further includes a plunger block having a corresponding array of m*n channels. Each channel accommodates a plunger and has an opening that is fluidically connected to the internal passageway (125) of a corresponding connector. The multichannel head further comprises a sealing mat (150) arranged between the connector block (110) and the plunger block, wherein the sealing mat comprises a corresponding array of m*n annular sealing elements for providing an airtight seal of the fluidic connection between the internal passageway of each connector and each opening of the corresponding plunger channel. The annular sealing elements are interconnected by a lattice of linkages that extend in lateral direction and in longitudinal direction, such that a cut-out region is formed between two opposing lateral linkages and two opposing longitudinal linkages. The sealing mat (150) is arranged on a receiving surface (116), which is provided with protrusions (117) that are shaped to pass through the cut-out regions of the sealing mat.
A cartridge for use in an electrowetting sample processing system, the cartridge having one or more inlet ports for introducing an input liquid into an internal gap of the cartridge, which has at least one hydrophobic surface for enabling an electrowetting induced movement of multiple microfluidic droplets separated from the input liquid. The cartridge further has at least one outlet port that is operably connected to the inlet port for providing a liquid flow through the cartridge, if a liquid driving force, in particular an electrowetting force or a pressure force, is applied to at least a part of the input liquid.
A method for minimizing the dead volume (Vd) in a vial (10) presenting a liquid (L) for aspiration is provided. The method comprises, after determining that the liquid volume (Vi) indicated to be available in the vial (10) is not sufficient for a further aspiration step, moving downward in direction towards the bottom of the vial (10) by means of a pipetting arm (20) presenting a pipetting tip (21) and along the z-axis of the pipetting arm (20) until the pipetting arm (20) comes to a stop in a first stop position (S1z). Then, the actual available liquid volume (Va) is calculated based i.a. on said first stop position (S1z). In case the calculated actual available liquid volume (Va) is sufficient, a further aspiration step can be executed. Furthermore, a liquid handling system for minimizing dead volume (Vd), a computer-implemented method for controlling a pipetting arm (20) of such a liquid handling system, and the use of a hysteresis determination method for minimizing dead volume (Vd) are provided.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
09 - Appareils et instruments scientifiques et électriques
Produits et services
Robots, namely, automatic apparatus for collecting, distributing or positioning objects and solid, liquid or gaseous substances Scientific apparatus and instruments, namely, robots for collecting, distributing, transporting or positioning of objects and solid, liquid and gaseous substances; scientific apparatus and instruments, namely, pipetting devices and sampling devices, dispensers and dosing apparatus
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Robots, namely, automatic apparatus for collecting, distributing or positioning objects and solid, liquid or gaseous substances Scientific apparatus and instruments, namely, robots for collecting, distributing, transporting or positioning of objects and solid, liquid and gaseous substances; scientific apparatus and instruments, namely, pipetting devices and sampling devices, dispensers and dosing apparatus Analytical apparatus and instruments for clinical diagnostic use and for veterinary use, including pipetting devices and sampling devices and dispensers
09 - Appareils et instruments scientifiques et électriques
Produits et services
Robots, namely, automatic apparatus for collecting,
distributing, transporting, positioning objects and solid,
liquid and gaseous substances. Scientific apparatus and instruments, namely, robots for
collecting, distributing, transporting, positioning objects
and solid, liquid and gaseous substances; scientific
apparatus and instruments, namely, pipetting devices and
sample collection devices, dispensers and dosing apparatus.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Robots, namely automatic machines for collecting,
distributing, transporting or positioning objects and solid,
liquid or gaseous substances. Scientific apparatus and instruments, namely robots for
collecting, distributing, transporting or positioning
objects and solid, liquid or gaseous substances; Scientific
apparatus and instruments, namely pipetting and sampling
devices, dispensers and dosing devices.
9.
METHOD OF OPERATING A PIPETTING SYSTEM, A PIPETTING SYSTEM, A TOOL, AND A COMPUTER-IMPLEMENTED METHOD
A method is described of operating a pipetting system (10) that has a worktable (12), at least one manipulator arm (18), and first and second Z-rods (20′,20″) arranged on the at least one manipulator arm (18). The method involves receiving by the second Z-rod (20″) a tool (24) via an adapter attached to the second Z-rod (20″), wherein the tool (24) has a central axis and a working area, the working area being defined by a circle which center is located on the central axis of the tool (24) and which radius being a distance between the central axis and a largest extension of an outline of the tool (24) in a projection.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
A method for aspirating a first liquid medium from a sample container with a laboratory automation device, wherein the first liquid medium is above a second liquid medium, which has a higher density and/or viscosity as the first liquid medium comprises: detecting a surface position of a surface of the first liquid medium; calculating an estimated interface position of an interface between the first liquid medium and the second liquid medium from the surface position and calculating a safety position between the surface position and the estimated interface position by adding a safety offset to the estimated interface position; and lowering a pipette of the laboratory automation device into the sample container and aspirating the first liquid medium from the sample container with the pipette by generating an underpressure in the pipette until a pipette tip of the pipette reaches the safety position.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
11.
LOG FILE EVALUATION OF LABORATORY AUTOMATION DEVICE WITH STATE MACHINES
A method for determining states of a laboratory automation device includes: receiving a log file from the laboratory automation device, the log file including entries of events that occurred during a procedure performed by the laboratory automation device, wherein the events have been created by components of the laboratory automation device and each entry includes at least an event time and an event type; providing a state machine of the laboratory automation device, the state machine encoding states of the laboratory automation device and transitions between the states, wherein each transition is starting at a state and points to another state and wherein each transition is associated with an entry scheme in the log file, the entry scheme including at least an event type; setting a current state of the laboratory automation device to a beginning state; moving through the entries of the log file along increasing event time and associating the entries with the current state; during the moving, when an entry scheme associated with a transition starting at the current state is identified in the log file, changing the current state to the state to which the transition (60) is pointing.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Robots, namely, automatic machines for collecting, distributing, transporting or positioning objects and solid, liquid or gaseous substances Scientific apparatus and instruments, namely, robots for collecting, distributing, transporting or positioning objects and solid, liquid or gaseous substances; scientific apparatus and instruments, namely, pipetting and sampling devices, dispensers and dosing devices
09 - Appareils et instruments scientifiques et électriques
Produits et services
Robots, namely, automatic machines for collecting, distributing, transporting or positioning objects and solid, liquid or gaseous substances Scientific apparatus and instruments, namely, robots for collecting, distributing, transporting or positioning objects and solid, liquid or gaseous substances; scientific apparatus and instruments, namely, pipetting and sampling devices, dispensers and dosing devices
A method for generating a control program for a laboratory automation device includes receiving configuration data of the laboratory automation device, generating a three-dimensional model of the components of the laboratory automation device from the configuration data, the three-dimensional model additionally including a virtual pipette; displaying the three-dimensional model with a virtual reality headset; receiving movement data of a motion sensing controller controlled by a user wearing the virtual reality headset, the movement data indicating a three-dimensional movement of the motion sensing controller in space; determining a movement of the virtual pipette in the three-dimensional model from the movement data and updating the three-dimensional model according to the movement of the virtual pipette; and generating a control program for the laboratory automation device from the movement data.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
A pipette tip extension attachable to a pipette tip with the pipette tip extension having a proximal end, a distal end, and exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall having an outer side and inner side and forming at the proximal end a reception aperture for inserting a pipette tip, and at a distal end a dispense aperture. An inner cavity is enclosed by the inner side of the exterior wall and one or more distance elements connected to the inner side of the exterior wall. The distance element(s) being configured to position a pipette tip within the inner cavity and to establish fluid uptake area adjacent the inner side of the exterior wall with the fluid uptake area extending from the dispense aperture towards the reception aperture and being in fluid connection with the surrounding atmosphere at the reception aperture.
A rotary valve comprises a stator member with a stator face, the stator member having at least two stator channels for conducting a fluid and opening into the stator face; a rotor member with a rotor face facing and in contact with the stator face, the rotor member having a rotor channel in the rotor face, wherein the rotor member is rotatable with respect to the stator member about a rotation axis, such that in a conducting position, the rotor channel interconnects the at least two stator channels to be in fluid communication; and a rotary encoder assembly adapted for determining a rotary position of the rotor member, the rotary encoder assembly comprising an encoder member and an encoder module, which is adapted to sense a rotary position of the encoder member. The encoder member is rigidly connected to the rotor member and surrounds the rotor member.
F16K 37/00 - Moyens particuliers portés par ou sur les soupapes ou autres dispositifs d'obturation pour repérer ou enregistrer leur fonctionnement ou pour permettre de donner l'alarme
F16K 31/04 - Moyens de fonctionnement; Dispositifs de retour à la position de repos magnétiques utilisant un moteur
F16K 11/08 - Soupapes ou clapets à voies multiples, p.ex. clapets mélangeurs; Raccords de tuyauteries comportant de tels clapets ou soupapes; Aménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des robinets à boisseau
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Custom manufacturing to the order and requirements of a
customer with regard to scientific devices and instruments
or with regard to modules of scientific devices and
instruments; custom manufacturing to the order and
requirements of a customer with regard to medical, surgical
and veterinary devices and instruments or with regard to
modules of medical, surgical and veterinary devices and
instruments; custom assembly to the order and requirements
of a customer with regard to scientific devices and
instruments or with regard to modules of scientific devices
and instruments; custom assembly to the order and
requirements of a customer with regard to medical, surgical
and veterinary devices and instruments or with regard to
modules of medical, surgical and veterinary devices and
instruments; processing and treatment of plastics; molding
of plastic materials. Planning and design of laboratory automation systems,
medical devices, and analysis instruments; Planning and
design of modules of laboratory automation systems, of
modules of medical devices, and of modules of analysis
instruments; custom development of laboratory automation
equipment, medical devices, and analysis instruments; custom
development of modules of laboratory automation systems, of
modules of medical devices, and modules of analysis
instruments; development of computer software for laboratory
automation equipment, for medical devices, and for analysis
instruments; development of software for modules of
laboratory automation systems, for modules of medical
devices, and of software for modules of analysis
instruments; technological services with regard to product
life-cycle management for technical products, including
development, production, product improvements,
decommissioning and disposal.
A robotic sample handling system (100) may be provided for performing sample handling tasks in a laboratory environment. The system may comprise at least one robotic arm (140), (142) which is controllable to be positioned in a plane parallel to a work area and along a Z-axis perpendicular to the work area, and a controller (180) configured to control the robotic arm to position and operate the robotic arm as part of a sample handling task. The work area may comprise a module (204) for use with one or more of the samples, wherein the module comprises a mechanism which is actuatable by downward force, and wherein the controller is configured to control the robotic arm to actuate the mechanism by pushing downward in Z-direction. For example, the module may be a stand (204) for a sample container which comprise a push-push mechanism which may be operated by the robotic arm to bring the sample in the sample container in a vicinity of an effector, such as a magnet or a heat source.
A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge contains an internal gap with at least one hydrophobic surface for enabling an electrowetting induced movement of a microfluidic droplet that has magnetic beads and further has a bead accumulation zone, into which the microfluidic droplet is transferable by electrowetting force and the magnetic beads are exposable to a magnetic force of a bead manipulation magnet. The internal gap has a bead extraction opening adjacent to the bead accumulation zone. The bead extraction opening provides a passage from the gap to an exterior space of the cartridge and is configured to removably receive the bead manipulation magnet for enabling an extraction of the magnetic beads from the microfluidic droplet by a removal of the bead manipulation magnet.
The invention relates to a multi-channel head (100) of a liquid handling apparatus for aspirating and dispensing a metered amount of liquid, comprising:
an array of connectors (130) for picking up an array of disposable tips, whereby a peripheral end of each connector is provided with an elastomeric seal (140);
an alignment plate (150) that is moveable in a z-direction and has a plurality of openings through which the connectors (130) extend,
a linear displacement mechanism (170b, 175), driven by a motor (180), for moving the alignment plate (150) in z-direction relative to the connectors, and a controller for controlling the motor.
The multi-channel head is configured to attach the array of disposable tips in a pick-up action, in which the multi-channel head (100) is lowered relative to the disposable tips so as to insert each connector into an internal passageway of a corresponding disposable tip by an amount sufficient to bring an upper collar of the disposable tips into contact with an underside (150s) of the alignment plate. This insertion deforms the elastomeric seal against the tip internal passageway so as to form a sealing contact therewith. The controller of the multi-channel head (100) is programmed such that once the pick-up action is complete, an alignment action is performed in which the alignment plate (150) is moved relative to connectors (130) by an amount sufficient to close any gap between the underside (150s) of the alignment plate and the upper surface of the tip collars that arises due to e.g. relaxation of the deformed seals (140).
A laboratory automation device comprises a workspace with liquid containers and a pipetting arm for moving liquids between the liquid containers; a housing enclosing the workspace; a door of the housing for accessing the workspace, wherein the door comprises a transparent display for displaying information and for allowing a person to view into the workspace and a tracking sensor for tracking an eye position of the person. The laboratory automation device is adapted for determining the eye position of the person from sensor data acquired with the tracking sensor; and for displaying information for a notification area in the workspace on the transparent display, such that the information is displayed from a perspective of the person in front of the notification area.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
A cooling module (106' ) for receiving a plurality of containers (116), said cooling module (106' ) comprising a housing (122) including at least one opening (124), a cooling block arranged into the housing (122), at least one compartment for receiving the containers (116) via the opening (124), and at least one cover ( 108, 108 ', 108 ' ' ) for covering the opening (124) against the exterior.
B01L 7/00 - Appareils de chauffage ou de refroidissement; Dispositifs d'isolation thermique
B01L 7/04 - Dispositifs d'isolation thermique, p.ex. manchons pour ballons
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
B01L 9/06 - Supports de tubes à essai; Porte-tubes à essai
24.
3D-PRINTED MASK FOR LYSING AT A LOCATION ON A TISSUE SECTION
Some embodiments are directed to a method for detaching tissue from a tissue section on a tissue slide. The method may include applying a 3D printed mask on top of the tissue section, the mask comprising barriers that define a cavity surrounding an area of interest on the tissue section, the cavity being open at a side facing the area of interest on the tissue section, dispensing a detaching liquid to the cavity, and allowing the detaching liquid to detach tissue at the area of interest, and aspirating the detaching liquid with the detached tissue from the cavity, and forwarding the liquid for further processing.
A method of measuring the alignment of one or more pipetting tips in an automated pipetting system where the one or more pipetting tips are mounted on one or more adapters of a pipetting head approximately perpendicular to the pipetting head mounting surface is disclosed. The orifices at the end of the one or more pipetting tips are mapped with an image capture device having a sensor placed in face and distant of the orifices. The method sends the acquired data from mapping the orifices of the one or more pipetting tips to the data processor, generating an image of the orifices of the one or more pipetting tips, determining the center positions of orifices, and delivering alignment information for the one or more pipetting tips.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
26.
METHOD AND DEVICE FOR DETECTING CONTACT OF A PIPETTE TIP WITH A LIQUID AS WELL AS A LABORATORY SYSTEM WITH SUCH A DEVICE
A method for detecting contact of a pipette tip with a surface of a liquid in a pipetting device is disclosed. The method consists of moving the pipette tip in the direction of the surface of the liquid thereby measuring an absolute capacitance between the pipette tip and a reference potential and generating a sampled output signal. A predicted momentary sample value of the output signal is generated based on a plurality of past sample values of the output signal. A contact signal indicative of the pipette tip being in contact with the surface of the liquid is generated based on comparing a momentary sample value of the output signal with the predicted momentary sample value of the output signal. A corresponding pipetting device capable of performing the method as a laboratory system, in particular an automated liquid processing system, with one or more such pipetting devices are proposed.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Robot, namely Automated machines for the uptake, discharge, conveying or positioning of objects or solid, liquid and gaseous substances. Scientific apparatus and instruments, namely Robots for the uptake, discharge, conveying or positioning of objects and solid, liquid or gaseous substances; Scientific apparatus and instruments, namely Pipetting and sampling devices, dispensers and dosage dispensers.
09 - Appareils et instruments scientifiques et électriques
Produits et services
Robot, namely Automated machines for the uptake, discharge, conveying or positioning of objects or solid, liquid and gaseous substances. Scientific apparatus and instruments, namely Robots for the uptake, discharge, conveying or positioning of objects and solid, liquid or gaseous substances; Scientific apparatus and instruments, namely Pipetting and sampling devices, dispensers and dosage dispensers.
29.
TRACKING OF LYSING AT A LOCATION ON A TISSUE SECTION
Some embodiments are directed to a method for tracking lysis progress in an automated lysing device. For example, the lysing device may be configured to execute multiple iterations of lysing at a defined location on the tissue section and imaging the defined location on the tissue section using a camera. From the images a lysing parameter may be determined to improve lysing.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
30.
IMAGE REGISTRATION WITH APPLICATION IN TISSUE TREATMENT
Some embodiments are directed to image registration. A rotation angle is determined and subsequently a translation vector. The rotation angle and translation vector together defining an alignment transformation between a first image and a second image. Determining the rotation angle may include iterating over multiple potential rotation angles, and determining alignment.
G06T 3/00 - Transformation géométrique de l'image dans le plan de l'image
G06T 7/33 - Détermination des paramètres de transformation pour l'alignement des images, c. à d. recalage des images utilisant des procédés basés sur les caractéristiques
A dark-field imaging system comprising a platform for holding biologic tissue or cells, constituting a plane forming two half-spaces. The dark-field imaging system further comprises a light source, which generates an incident light targeting the biologic tissue or cells, and a camera to detect diffuse reflection off the biologic tissue or cells. The light source is placed at a first angle (a) relative to the plane, and the camera is placed at a second angle (β) relative to the plane wherein the light source, the camera, and the biologic tissue or cells are arranged in the same one of the two half-spaces formed by the plane. The incident light that is not reflected by the biologic tissue or cells reaches the platform, which comprises a specularly reflecting material that reflects the incident light at least in part by specular reflection. Use of such a dark-field imaging system in an application for interacting with areas of interest of biological samples, where the dark-field imaging system takes high-contrast images of biologic tissue or cells in an automated laboratory system, and an automated laboratory system comprising such a dark-field imaging system.
An incubation cassette for reducing liquid evaporation from wells of a microplate with a frame for receiving a microplate with wells, the frame having a central first opening surrounded by an inner wall, the dimensions are designed for inserting a microplate, and the frame having an outer wall that runs essentially parallel to the inner wall and which is attached to the inner wall connects so that a liquid reservoir surrounding the first central opening for receiving a liquid is formed by the two walls and the intermediate base is disclosed. The incubation cassette also includes a float provided in the liquid reservoir that can be brought into fluid contact with the liquid held in the liquid reservoir in such a way that the float is in relation to the liquid level of the liquid in the liquid reservoir absorbed liquid experiences buoyancy.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
B01L 7/00 - Appareils de chauffage ou de refroidissement; Dispositifs d'isolation thermique
B01L 9/00 - Dispositifs de support; Dispositifs de serrage
C12M 1/32 - Inoculateur ou échantillonneur du type à champs multiples ou en continu
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p.ex. par des compteurs de colonies
G01F 23/68 - Indication ou mesure du niveau des liquides ou des matériaux solides fluents, p.ex. indication en fonction du volume ou indication au moyen d'un signal d'alarme par des flotteurs du type à flotteur libre en utilisant des moyens d'indication actionnés électriquement
37 - Services de construction; extraction minière; installation et réparation
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Installation, assembly, repair, maintenance, overhaul,
inspection and monitoring of robots, scientific, optical,
analytical, measuring, dosing, checking and control
apparatus and instruments, pipetting and sampling devices,
dispensers, pumps and dosing apparatus for laboratory use,
and imaging devices; providing information relating to all
the aforementioned services. Custom manufacturing to the order and requirements of a
customer with regard to scientific devices and instruments
or with regard to modules of scientific devices and
instruments; Custom manufacturing to the order and
requirements of a customer with regard to medical and
veterinary devices and instruments or with regard to modules
of medical and veterinary devices and instruments; custom
assembly to the order and requirements of a customer with
regard to scientific devices and instruments or with regard
to modules of scientific devices and instruments; custom
assembly to the order and requirements of a customer with
regard to medical and veterinary devices and instruments or
with regard to modules of medical and veterinary devices and
instruments; processing and treatment of plastics; molding
of plastics. Educational and training services, including provision of
data and materials for educational purposes for users of
laboratory apparatus; Providing training and educational
materials online. Planning and design of automated laboratory systems; Custom
development of laboratory automation equipment and analysis
instruments; development of computer software; technological
services with regard to product life cycle management for
technical products, including development, production,
product improvements, decommissioning and disposal;
providing temporary use of non-downloadable software for
controlling and monitoring apparatus and instruments for
laboratories, for controlling and monitoring medical
apparatus and for the analysis of measurement results;
providing temporary use of non-downloadable or
internet-based software for use in the automation of
laboratories; hosting internet platforms [software]; hosting
internet portals; hosting computerized data, files,
applications and information; providing computer programs in
data networks; providing software [Software as a service,
SaaS]; platform as a Service [PaaS]; installation, repair
and maintenance of software; backup of electronic data;
analysis and evaluation of products and services with regard
to possible future uses.
A pipette includes an end section, a first section, a second section and a third section aligned along a central axis of the pipette tip. The end section comprises an orifice for aspirating and dispensing a fluid. A first kink is formed in an inner surface of the pipette tip between the first section and the second section, such that an angle between the inner surface of the first section and the central axis is smaller than an angle between the inner surface of the second section and the central axis. A second kink is formed in the inner surface of the pipette tip between the second section and the third section, such that the angle between the inner surface of the second section and the central axis is smaller than an angle between the inner surface of the third section and the central axis.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Biochemical reagents for scientific or research purposes, in
particular for use related to nucleic acid analysis, protein
analysis, protein profiling and analysis of cell components. Biochemical reagents for clinical medical diagnostic use and
use in veterinary medicine, in particular for use related to
nucleic acid analysis, protein analysis, protein profiling
and analysis of cell components. Scientific apparatus and instruments, namely, devices for
pipetting, imaging, extraction from tissue samples and
purification of nucleic acids and proteins; Pipetting tip
extensions for use in laboratory apparatus; software for
image analysis; application software; software for
controlling scientific apparatus and instruments. Analytical apparatus and instruments for clinical diagnostic
use and veterinary diagnostic use, namely, devices for
pipetting, imaging, extraction from tissue samples and
purification of nucleic acids and proteins.
36.
Cartridge, electrowetting sample processing system and droplet formation
A cartridge for use in an electrowetting sample processing system, the cartridge having at least one inlet port for introducing an input liquid in an internal gap of the cartridge, wherein the gap has at least one hydrophobic surface and is configured to provide an electrowetting induced movement of a microfluidic droplet of input liquid, wherein the input liquid has a carrier liquid and a processing liquid and the gap has a capture zone that is configured to capture at least a part of the processing liquid as a microfluidic droplet by use of electrowetting force and the gap further has a transfer zone that is configured to provide a passage for the carrier liquid next to the microfluidic droplet, while processing liquid is captured in the capture zone.
A cover for a fluid container having an essentially plane cover plate for closing at least one opening of at least one fluid container and at least two ports, and each port has a through channel extending through the entire thickness of the cover plate and a fluid impermeable first membrane is arranged over the entire cross section of the through channel of the first port and an at least gas permeable second membrane is arranged over the entire cross section of the through channel of the second port is disclosed.
A rotary valve includes a stator member with a planar stator face, the stator member having a plurality of stator channels for conducting a fluid; and a rotor member with a planar rotor face facing and in contact with the stator face, the rotor member having a rotor channel; wherein the rotor member is rotatable with respect to the stator member about a rotation axis, such that in a conducting position, the rotor channel interconnects two of the stator channels and the two stator channels are in fluid communication; wherein at least one of the stator channels has a transverse channel section opening into the stator face and running transversely with respect to the rotation axis; wherein the rotor channel has a bottom, which at an intersection end of the rotor channel is inclined with respect to the rotation axis, such that the rotor channel elongates an inner surface of the stator channel, when the rotor member is in the conducting position.
F16K 11/074 - Soupapes ou clapets à voies multiples, p.ex. clapets mélangeurs; Raccords de tuyauteries comportant de tels clapets ou soupapes; Aménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des tiroirs à éléments de fermeture articulés à pivot à faces d'obturation planes
A method is disclosed for controlling at least one of aspirating and of dispensing a liquid dose or of producing a liquid dose in a pipette or in receptacle, the method having the steps of first loading a first pipette with a first working medium at a first pressure having a first sign with respect to a reference pressure, thereby dispensing the liquid dose into the receptacle or aspirating the liquid dose into the first pipette, second loading a second pipette with a second working medium at a second pressure having a second sign with respect to the reference pressure, thereby dispensing the liquid dose into the receptacle or aspirating the liquid dose into the second pipette, discharging a pressure in the first working medium through a controlled valve arrangement to the reference pressure between first and second loadings. A pipetting device is also disclosed.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Biochemical reagents for scientific or research purposes, in particular for use related to nucleic acid analysis, protein analysis, protein profiling and analysis of cell components Biochemical reagents for clinical medical diagnostic use and use in veterinary medicine, in particular for use related to nucleic acid analysis, protein analysis, protein profiling and analysis of cell components Scientific apparatus and instruments, namely, devices for laboratory pipetting, non-medical imaging devices for imaging of cells, cell colonies, biological tissues, electrophoresis gels, protein arrays and nucleic acid arrays, laboratory devices for extraction from tissue samples, and laboratory apparatus for purification of nucleic acids and proteins; Disposable materials for use in laboratory apparatus, namely, Pipette tips and pipetting tip extensions for use in laboratory apparatus; Downloadable or recorded software for image analysis; Downloadable or recorded application workflow programming software; Downloadable or recorded computer software for controlling scientific apparatus and instruments Medical and veterinary analytical apparatus and instruments for clinical diagnostic use and veterinary diagnostic use, namely, medical and veterinary devices for pipetting, imaging, extraction from tissue samples and purification of nucleic acids and proteins; all the aforementioned products for clinical medical diagnostic and veterinary diagnostic purposes Providing online non-downloadable computer software for image analysis; Providing online non-downloadable application programming interface software; Providing online non-downloadable computer software for controlling scientific apparatus and instruments
37 - Services de construction; extraction minière; installation et réparation
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Installation, assembly, repair, maintenance, and overhaul of robots, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, pumps and dosing apparatus for laboratory use, and imaging devices; providing information relating to all the aforementioned services Custom manufacturing to the order and requirements of a customer with regard to scientific devices and instruments or with regard to modules of scientific devices and instruments; Custom manufacturing to the order and requirements of a customer with regard to medical and veterinary devices and instruments or with regard to modules of medical and veterinary devices and instruments; Custom assembly to the order and requirements of a customer with regard to scientific devices and instruments or with regard to modules of scientific devices and instruments; Custom assembly to the order and requirements of a customer with regard to medical and veterinary devices and instruments or with regard to modules of medical and veterinary devices and instruments; Processing and treatment of plastics; Molding of plastics Educational and training services, namely, conducting classes, seminars and workshops in the field of laboratory apparatus and the provision of data and materials in connection therewith for educational purposes for users of laboratory apparatus; providing online education and trainings, namely, conducting classes, seminars and workshops in the field of laboratory apparatus Planning and design of laboratory automation systems; order development of laboratory automation equipment and analysis instruments; development of computer software; Technological advisory services with regard to product life cycle management for technical products, namely, advisory services for the development, production, product improvements, decommissioning and disposal of technical products; providing temporary use of non-downloadable software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; providing temporary use of non-downloadable or internet-based software for use in the automation of laboratories; providing internet platforms, namely, providing on-line, non-downloadable, internet-based software for use in the automation of laboratories, and for use in controlling and monitoring apparatus and instruments for laboratories, in controlling and monitoring medical apparatus and in the analysis of measurement results; hosting internet portals for others; hosting computerized data, files, applications and information of others; providing computer programs in data networks, namely, on-line non-downloadable software programs for use in the automation of laboratories, and for use in controlling and monitoring apparatus and instruments for laboratories, in controlling and monitoring medical apparatus and in the analysis of measurement results; providing software as a service (SaaS) featuring software for use in the automation of laboratories, and for use in controlling and monitoring apparatus and instruments for laboratories, in controlling and monitoring medical apparatus and in the analysis of measurement results; Platform as a Service (PaaS) featuring computer software platforms for use in the automation of laboratories, and for use in controlling and monitoring apparatus and instruments for laboratories, in controlling and monitoring medical apparatus and in the analysis of measurement results; installation, repair and maintenance of software; backup of electronic data; analysis and evaluation of products and services with regard to possible future uses; Remote monitoring of the functioning and use of technology in the nature of robots, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, pumps and dosing apparatus for laboratory use, and imaging devices; Providing information in the field of remote monitoring of the functioning and use of technology in the nature of robots, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, pumps and dosing apparatus for laboratory use, and imaging devices
42.
DISPLACEMENT DEVICE AND METHOD FOR DISPLACING FLUID VOLUMES
A displacement device for displacing a displacement volume is disclosed. The device has a first fluid space and a second fluid space. A first piston is arranged in a movable manner within the first fluid space. The first fluid space is connectable to a pipetting device. The first piston is actuatable by an actuation volume of air or of liquid provided by the pipetting device. A second piston is arranged in a movable manner within the second fluid space. The second piston is constructed to displace a displacement volume of a fluid located within the second fluid space when the second piston is actuated. The second piston is actuated in dependence on the first piston that is actuated by the actuation volume. The actuation volume is different from the displacement volume, and a pipetting system has a displacement device and a method of displacing a displacement volume.
A method for minimizing the dead volume (Vd) in a vial (10) presenting a liquid (L) for aspiration is provided. The method comprises, after determining that the liquid volume (Vi) indicated to be available in the vial (10) is not sufficient for a further aspiration step, moving downward in direction towards the bottom of the vial (10) by means of a pipetting arm (20) presenting a pipetting tip (21) and along the z-axis of the pipetting arm (20) until the pipetting arm (20) comes to a stop in a first stop position (Slz). Then, the actual available liquid volume (Va) is calculated based i.a. on said first stop position (Slz). In case the calculated actual available liquid volume (Va) is sufficient, a further aspiration step can be executed. Furthermore, a liquid handling system for minimizing dead volume (Vd), a computer-implemented method for controlling a pipetting arm (20) of such a liquid handling system, and the use of a hysteresis determination method for minimizing dead volume (Vd) are provided.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
A door for a laboratory workstation is disclosed. The laboratory workstation has a horizontally extending work surface for providing a working area. The door is movable in relation to the work surface in a vertical direction perpendicular to the work surface between a safety position, in which the door closes the working area for manual access of a user, an access position in which the working area is open for manual access of a user, and a loading position.
A method for aspirating a first liquid medium of two liquid media of different density from a sample container comprises: lowering a pipette of the laboratory automation device into the sample container until a pipette tip of the pipette has passed a lowering distance from the surface of the first liquid medium in the sample container, wherein the lowering distance is chosen, such that the pipette tip passes at least an aspiration volume in the sample container; aspirating liquid from the sample container during the lowering of the pipette by generating an underpressure in the pipette, wherein the first liquid medium is aspirated, and after the interface and the pipette tip pass each other, the second liquid medium of the two liquid media is aspirated; measuring a pressure in the pipette during the lowering of the pipette and detecting a position of the interface, when a slope of the pressure changes; when the lowering distance has been passed and no interface is detected, aspirating the aspiration volume from the first liquid medium and dispensing the aspiration volume of the first liquid medium into a further sample container.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
46.
Receiving frame for receiving a support plate for pipette tips
A receiving frame for a support plate for pipette tips that is formed from two opposing longitudinal walls and two opposing transverse walls, each has an upper side and a lower side and laterally enclose an interior space is disclosed. The upper sides of the longitudinal walls and transverse walls together form a circumferential support surface on which a support plate for pipette tips can be reversibly placed. The receiving frame has a footprint on the lower side of the longitudinal walls and the transverse walls.
The invention relates to an arrangement of a gripper finger and a clamp for use in an automated parallel gripper comprising first and second gripper fingers that are moveable in a direction of translation (y), whereby the clamp is connected to the gripper finger at an underside thereof, so as to be rotational about a vertical axis of rotation (135). The clamp has a front face with a contact surface for engagement with a lateral edge of an item to be gripped and has a default orientation in which the front face is parallel to a lateral direction (x) that is perpendicular to the direction of translation (y) and to the vertical rotation axis (135). The arrangement is additionally provided with a self-alignment feature which comprises first and second biasing mechanisms arranged at either side of the rotation axis (135) in lateral direction (x). Each biasing mechanism has a first part (151, 152) connected to the finger and a second part (131, 132) connected to the clamp and is configured to exert a centering force that urges the first and second parts of each biasing mechanism into alignment with each other. When the clamp is in the default orientation, each biasing mechanism is preloaded to exert an equal moment load on the clamp in the direction of translation (y).
A robotic arm of an automated pipetting system has a pipetting tip adapter and a slide switch to detect the presence of pipetting tips on the pipetting tip adapter is disclosed. The slide switch has first support member and second support member configured to slide relative to one another between first and second positions along a movement axis, an electrically conducting contact pad arranged on the first support member, an electrically conducting terminal physically attached to second support member in physical contact with the contact pad when support members are in first position, where the terminal is a first resilient wiping member expanding along the movement axis, first wiping member is not in physical contact with the contact pad when support members are in second position, and an electric current can flow between first wiping member and the contact pad when support members are in first position.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
H01H 1/40 - Contact monté de façon que sa surface de contact soit de niveau avec l'isolation contiguë
H01H 3/16 - Organes moteurs, c. à d. pour actionner le mécanisme d'entraînement par une force mécanique extérieure à l'interrupteur adaptés pour être actionnés dans une position limite ou autre position prédéterminée dans le trajet d'un corps, le mouvement relatif de l'interrupteur et du corps ayant principalement un autre but que d'actionner l'interrupteur, p.ex. un interrupteur
A rotary valve (10) comprises a stator member (36) with a stator face (54), the stator member (36) having at least two stator channels (46, 48) for conducting a fluid and opening into the stator face (54); a rotor member (24) with a rotor face (52) facing and in contact with the stator face (54), the rotor member (24) having a rotor channel (50) in the rotor face (52), wherein the rotor member (24) is rotatable with respect to the stator member (36) about a rotation axis (A), such that in a conducting position, the rotor channel (50) interconnects the at least two stator channels (46, 48) to be in fluid communication; and a rotary encoder assembly (33) adapted for determining a rotary position of the rotor member (24), the rotary encoder assembly (33) comprising an encoder member (34) and an encoder module (35), which is adapted to sense a rotary position of the encoder member (34). The encoder member (34) is rigidly connected to the rotor member (24) and surrounds the rotor member (24).
F16K 11/072 - Soupapes ou clapets à voies multiples, p.ex. clapets mélangeurs; Raccords de tuyauteries comportant de tels clapets ou soupapes; Aménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des tiroirs à éléments de fermeture articulés à pivot
F16K 31/04 - Moyens de fonctionnement; Dispositifs de retour à la position de repos magnétiques utilisant un moteur
F16K 37/00 - Moyens particuliers portés par ou sur les soupapes ou autres dispositifs d'obturation pour repérer ou enregistrer leur fonctionnement ou pour permettre de donner l'alarme
A robotic liquid handling system may be provided comprising a robotic arm and a controller configured to control the robotic arm to position and operate the robotic arm in a workspace of the robotic liquid handling system. The controller may be configured to, as part of a liquid handling task, control the robotic arm to open a reagent reservoir, wherein the reagent reservoir has an opening which is sealed by a foil. The controller may be configured to control the robotic arm to open the foil by controlling the robotic arm to, using a cutting tip (260), cut at least two flaps in the foil, and using a blunt protrusion, push the at least two flaps downwards into the reagent reservoir to clear at least part of the opening of the reagent reservoir. Further aspects of the invention relate to a computer-implemented method for controlling a robotic arm and to an opening tool (200) comprising the cutting tip and the blunt protrusion.
A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge has a liquid input port for introducing an input liquid into an internal gap of the cartridge, the input liquid providing for at least one droplet, directly or via a liquid separation process within the internal gap, and the internal gap having at least one hydrophobic surface, at least one processing zone for processing samples located in the processing zone, and a delivery zone for delivering the at least one droplet from the liquid input port to the at least one processing zone. The delivery zone is configured to provide a repeating pattern of interacting electrowetting force for simultaneously transporting the at least one droplet within the delivery zone.
A multichannel pipetting plate comprises a plurality of connectors arranged in a lattice; wherein each connector is fluidically connectable to a pipetting tip; wherein each connector comprises an interface at which a friction contact between the connector and a foot of the pipetting tip is established; wherein the interfaces of the connectors are arranged in different planes, such that, at least at a border region of the pipetting plate, along each row and along each column of the lattice, at least three consecutive interfaces are arranged in at least two different planes.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
A pipette tip extension attachable to a pipette tip is disclosed. The pipette tip extension has a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end. The exterior wall has an outer side and an inner side and forms at the proximal end a reception aperture for inserting a pipette tip. The pipette tip extension also has a bottom at the distal end, an inner cavity enclosed by the inner side of the exterior wall and the bottom, and one or more distance elements arranged at the inner side of the exterior wall and protruding into the inner cavity.
B03C 1/01 - Prétraitement spécialement adapté à la séparation magnétique par addition d'agents magnétiques
B03C 1/32 - Séparation magnétique agissant sur le milieu qui contient la substance à séparer, p.ex. séparation magnéto-gravimétrique, magnéto-hydrostatique ou magnéto- hydrodynamique
A rotary valve (10) comprises a stator member (36) with a planar stator face, the stator member (36) having a plurality of stator channels (46, 48) for conducting a fluid; and a rotor member (24) with a planar rotor face (52) facing and in contact with the stator face, the rotor member (24) having a rotor channel (50); wherein the rotor member (24) is rotatable with respect to the stator member (36) about a rotation axis (A), such that in a conducting position, the rotor channel (50) interconnects two of the stator channels (46, 48) and the two stator channels (46, 48) are in fluid communication; wherein at least one of the stator channels (48) has a transverse channel section (74) opening into the stator face (54) and running transversely with respect to the rotation axis (A); wherein the rotor channel (50) has a bottom (64), which at an intersection end (62) of the rotor channel (50) is inclined with respect to the rotation axis (A), such that the rotor channel (50) elongates an inner surface of the stator channel (48), when the rotor member (24) is in the conducting position.
F16K 3/08 - Robinets-vannes ou tiroirs, c. à d. dispositifs obturateurs dont l'élément de fermeture glisse le long d'un siège pour l'ouverture ou la fermeture à faces d'obturation planes; Garnitures d'étanchéité à cet effet avec éléments de fermeture articulés à pivot en forme de plaques disposées entre l'alimentation et l'évacuation les plaques étant circulaires et pivotant autour de leur centre
F16K 11/074 - Soupapes ou clapets à voies multiples, p.ex. clapets mélangeurs; Raccords de tuyauteries comportant de tels clapets ou soupapes; Aménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des tiroirs à éléments de fermeture articulés à pivot à faces d'obturation planes
G01N 30/20 - Injection utilisant une valve d'échantillonnage
A method of treating an isolated area of a sample with a liquid is disclosed. The method has the steps of generating an isolated area of a sample by a first fluid reservoir where the first fluid reservoir enclosing a distal end of a second fluid reservoir and the isolated area of the sample being sealed towards the remaining area of the sample, bringing the isolated area of the sample into fluid connection with the second fluid reservoir, dispensing a fluid from the second fluid reservoir into the first fluid reservoir thereby generating a fluid flow on the sample at the isolated area in a first direction, and aspirating the fluid from the first fluid reservoir into the second fluid reservoir thereby generating a fluid flow on the sample at the isolated area in a second direction.
A method for classifying liquid handling procedures comprises includes receiving measurement data encoding a measurement curve of measurements over time during at least a part of a liquid handling procedure; inputting the measurement data into a neural network; and calculating at least one quality value for the liquid handling procedure with the neural network.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
A pipette tip extension attachable to a pipette tip having a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall has an outer side and an inner side and forms at the proximal end a reception aperture for inserting a pipette tip, and at the distal end a dispense aperture. The pipette tip extension further has an inner cavity, a distance element connected to the inner side of the exterior wall, and a constriction element.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
A pipette tip extension attachable to a pipette tip is disclosed. The pipette tip extension has a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end. The exterior wall has an outer side and an inner side and forms at the proximal end a reception aperture for inserting a pipette tip. The pipette tip extension further has a bottom at the distal end, an inner cavity enclosed by the inner side of the exterior wall and the bottom, one or more distance elements arranged at the inner side of the exterior wall and protruding into the inner cavity, and a coating for interacting with a fluid present in a fluid uptake area.
B03C 1/01 - Prétraitement spécialement adapté à la séparation magnétique par addition d'agents magnétiques
B03C 1/32 - Séparation magnétique agissant sur le milieu qui contient la substance à séparer, p.ex. séparation magnéto-gravimétrique, magnéto-hydrostatique ou magnéto- hydrodynamique
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
59.
LABORATORY AUTOMATION DEVICE WITH TRANSPARENT DISPLAY IN DOOR
A laboratory automation device (10) comprises a workspace (26) with liquid containers (16) and a pipetting arm (20) for moving liquids (18) between the liquid containers (16); a housing (28) enclosing the workspace (26); a door (30) of the housing (28) for accessing the workspace (26), wherein the door (30) comprises a transparent display (32) for displaying information (34) and for allowing a person to view into the workspace (26); and a tracking sensor (36) for tracking an eye position (46) of the person (42). The laboratory automation device (10) is adapted for determining the eye position (46) of the person (42) from sensor data acquired with the tracking sensor (36); and for displaying information (34b) for a notification area (48) in the workspace (26) on the transparent display (32), such that the information (34b) is displayed from a perspective of the person (42) in front of the notification area (48).
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
G06F 3/01 - Dispositions d'entrée ou dispositions d'entrée et de sortie combinées pour l'interaction entre l'utilisateur et le calculateur
A robotic sample handling system (100) may be provided for performing sample handling tasks in a laboratory environment. The system may comprise at least one robotic arm (140), (142) which is controllable to be positioned in a plane parallel to a work area and along a Z-axis perpendicular to the work area, and a controller (180) configured to control the robotic arm to position and operate the robotic arm as part of a sample handling task. The work area may comprise a module (204) for use with one or more of the samples, wherein the module comprises a mechanism which is actuatable by downward force, and wherein the controller is configured to control the robotic arm to actuate the mechanism by pushing downward in Z-direction. For example, the module may be a stand (204) for a sample container which comprise a push-push mechanism which may be operated by the robotic arm to bring the sample in the sample container in a vicinity of an effector, such as a magnet or a heat source.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
B01L 9/00 - Dispositifs de support; Dispositifs de serrage
61.
PIPETTE TIP EXTENSION, PIPETTE TIP, ASSEMBLY OF PIPETTE TIP AND PIPETTE TIP EXTENSION, AND METHOD OF USE
A pipette tip extension having a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall has an outer side and an inner side and encloses an inner cavity which is delimited by the inner side of the exterior wall. The exterior wall forms at the proximal end a reception aperture. The pipette tip extension further has one or more distance elements arranged at the inner side of the exterior wall and protruding into the inner cavity.
A digital microfluidics system with electrodes attached to a substrate and covered by a hydrophobic surface and a control unit for manipulating liquid droplets by electrowetting, providing in close proximity to electrodes a magnetic conduit for directing a magnetic field of a backing magnet to the first hydrophobic surface, providing on the hydrophobic surface a liquid droplet that has magnetically responsive beads moving by electrowetting the liquid droplet with the magnetically responsive beads until a part of which is placed atop of the magnetic conduit, actuating the backing magnet of the magnetic conduit and attracting/concentrating magnetically responsive beads while actuating the backing magnet, moving by electrowetting the liquid droplet with decreased number of magnetically responsive beads away from the specific magnetic conduit. Also disclosed are a method for suspending magnetically responsive beads in liquid portions or droplets in digital microfluidics and a disposable cartridge to carry out the methods.
A centrifugal processing unit for directing the movement of substances within a sample processing cartridge has a rotor with an accommodation for receiving the sample processing cartridge, the accommodation only allowing a free pivoting motion of the cartridge about a respective pivot axis, wherein each pivot axis is orthogonal to the rotor axis and to a respective force vector of a centrifugal force, a rotor drive to create the centrifugal force, a blocking element, allowing the free pivoting motion of the cartridge in a release position and preventing the free pivoting motion in a blocking position, wherein the blocking element is arranged on the rotor spaced apart above the accommodation is disclosed.
B04B 5/04 - Appareils à chambre radiale pour séparer des mélanges essentiellement liquides, p.ex. butyromètres
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
64.
CARTRIDGE, DIGITAL MICROFLUIDICS SYSTEM AND METHOD OF CONTROL AND MANIPULATION OF LIQUIDS
A cartridge configured to control and manipulate liquids and to be positioned at a cartridge accommodation site of a digital microfluidics system is disclosed. The digital microfluidics system has a number or array of individual electrodes attached to a first substrate or PCB, a central control unit in operative contact with individual electrodes for controlling selection and for providing a number of individual electrodes that define a path of individual electrodes with voltage for manipulating liquid portions or liquid droplets by electrowetting, and a cartridge accommodation site that is configured for taking up the cartridge.
Devices and corresponding methods for capacitive foam detection in liquid containers are disclosed. The device has a sensor with a measurement electrode having a plurality of sub-electrodes, a bottom plate that is used as a counter electrode for arranging a liquid container, a sensor electronic unit that is connected to the measurement electrode and the bottom plate and is adapted to determine an impedance, in particular a capacitance, between the measurement electrode and the bottom plate, and an evaluation unit, the measurement electrode being arranged substantially perpendicularly to the bottom plate.
G01N 27/22 - Recherche ou analyse des matériaux par l'emploi de moyens électriques, électrochimiques ou magnétiques en recherchant l'impédance en recherchant la capacité
G01F 23/263 - Indication ou mesure du niveau des liquides ou des matériaux solides fluents, p.ex. indication en fonction du volume ou indication au moyen d'un signal d'alarme en mesurant des variables physiques autres que les dimensions linéaires, la pression ou le poids, selon le niveau à mesurer, p.ex. par la différence de transfert de chaleur de vapeur ou d'eau en mesurant les variations de capacité ou l'inductance de condensateurs ou de bobines produites par la présence d'un liquide ou d'un matériau solide fluent dans des champs électriques ou électromagnétiques en mesurant les variations de capacité de condensateurs
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
07 - Machines et machines-outils
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
37 - Services de construction; extraction minière; installation et réparation
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical products for use in industry and science; reagents
for biological and chemical analysis; reagents for research
purposes; reagents for use in analytical apparatus. Reagents for use in analytical apparatus for clinical
diagnostics; diagnostic reagents and analysis reagents for
use for medical purposes in scientific and clinical
laboratories; diagnostic reagents and analysis reagents for
medical use; immunoassay reagents for clinical diagnostics;
reagents for medical use; reagents for use in clinical
diagnostics and for veterinary use, in particular for use in
clinical or veterinary nucleic acid-based diagnostics. Robots; conveyors; automatic handling machines
[manipulators]; robots, namely automatic machines for
collecting, distributing, transporting or positioning
objects and solid, liquid or gaseous substances. Scientific, optical, analytical, measuring, dosing, checking
and control apparatus and instruments, in particular for use
in laboratories; analytical apparatus and instruments for
scientific or non-medical use; pipetting devices and
sampling devices, dispensers, motorized syringe dilutors,
pumps and dosing apparatus for laboratory use; robots for
laboratory automation and robots for the automation of
analysis processes; laboratory apparatus and instruments
used for extraction; microplate readers, namely light
absorption measuring apparatus and luminescence and
fluorescence measuring apparatus; imaging devices for
scientific purposes; microplate washers; genomics
automation devices; disposable pipette tips for laboratory
use; disposable containers for reagents and samples in
connection with pipetting devices; microplates; disposable
materials for use in laboratory apparatus; cell counting
chambers for scientific use; extraction plates; extraction
columns; syringes for dilutors; valves for dilutors;
software for controlling laboratory apparatus and for
controlling medical apparatus; software for evaluation of
measurement results; software for image analysis; computer
software; application software; software downloadable from
computer networks and clouds; software for use in remote
monitoring of laboratory apparatus; software for remote
maintenance of laboratory apparatus; software for
connecting laboratory apparatus; software for use in the
automation of laboratories; training software; downloadable
electronic information and publications; recorded data
files; downloadable course materials for training and
education. Analytical apparatus and instruments for clinical diagnostic
use and for veterinary use, including light absorption
measuring apparatus and luminescence and fluorescence
measuring apparatus, pipetting devices and sampling devices,
dispensers, motorized syringe dilutors, pumps and dosing
apparatus for laboratories; disposable materials for use in
analytical apparatus and instruments for clinical diagnostic
use and for veterinary use; disposable pipette tips for use
in analytical apparatus and instruments for clinical
diagnostic use and for veterinary use. Installation, assembly, repair, maintenance, overhaul,
inspection and monitoring of automatic handling machines
[manipulators], scientific, optical, analytical, measuring,
dosing, checking and control apparatus and instruments,
pipetting and sampling devices, dispensers, motorized
syringe dilutors, pumps and dosing apparatus for laboratory
use, laboratory apparatus and instruments used for
extraction, microplate readers, imaging devices for
scientific use, microplate washers and genomics automation
devices; installation, assembly, repair, maintenance and
overhaul of robots and conveyors; providing information
relating to all the aforementioned services. Educational and training services, including provision of
data and materials for educational purposes for users of
laboratory apparatus; providing online education and
trainings; arranging and conducting instructional courses,
workshops and distance learning [training], in particular in
the field of laboratory apparatus; publication of printed
matter and electronic media, in particular training and
information material in the field of laboratory apparatus;
providing non-downloadable electronic publications online. Scientific and technological services, research services and
technical design services relating hereto; analysis and
research services; planning and design of laboratory
automation systems; order development of laboratory
automation equipment and analysis instruments; development
of computer software; providing temporary use of
non-downloadable software for controlling and monitoring
apparatus and instruments for laboratories, for controlling
and monitoring medical apparatus and for the analysis of
measurement results; providing temporary use of
non-downloadable or internet based software for use in the
automation of laboratories; providing internet platforms
[software]; hosting web portals; hosting computerized
data, files, applications and information; providing
computer programs in data networks; providing software
[Software as a service, SaaS]; Platform as a Service
[PaaS]; installation, repair and maintenance of software;
backup of electronic data; analysis and evaluation of
products and services with regard to possible future uses;
inspection of robots and conveyors for quality control
purposes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
07 - Machines et machines-outils
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
37 - Services de construction; extraction minière; installation et réparation
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical products for use in industry and science; reagents
for biological and chemical analysis; reagents for research
purposes; reagents for use in analytical apparatus. Reagents for use in analytical apparatus for clinical
diagnostics; diagnostic reagents and analysis reagents for
use for medical purposes in scientific and clinical
laboratories; diagnostic reagents and analysis reagents for
medical use; immunoassay reagents for clinical diagnostics;
reagents for medical use; reagents for use in clinical
diagnostics and for veterinary use, in particular for use in
clinical or veterinary nucleic acid-based diagnostics. Robots; conveyors; automatic handling machines
[manipulators]; robots, namely automatic machines for
collecting, distributing, transporting or positioning
objects and solid, liquid or gaseous substances. Scientific, optical, analytical, measuring, dosing, checking
and control apparatus and instruments, in particular for use
in laboratories; analytical apparatus and instruments for
scientific or non-medical use; pipetting devices and
sampling devices, dispensers, motorized syringe dilutors,
pumps and dosing apparatus for laboratory use; robots for
laboratory automation and robots for the automation of
analysis processes; laboratory apparatus and instruments
used for extraction; microplate readers, namely light
absorption measuring apparatus and luminescence and
fluorescence measuring apparatus; imaging devices for
scientific use; microplate washers; genomics automation
devices; disposable pipette tips for laboratory use;
disposable containers for reagents and samples in connection
with pipetting devices; microplates; disposable materials
for use in laboratory apparatus; cell counting chambers for
scientific use; extraction plates; extraction columns;
syringes for dilutors; valves for dilutors; software for
controlling laboratory apparatus and for controlling medical
apparatus; software for evaluation of measurement results;
software for image analysis; computer software; application
software; software downloadable from computer networks and
clouds; software for use in remote monitoring of laboratory
apparatus; software for remote maintenance of laboratory
apparatus; software for connecting laboratory apparatus;
software for use in the automation of laboratories; training
software; downloadable electronic information and
publications; recorded data files; downloadable course
materials for training and education. Analytical apparatus and instruments for clinical diagnostic
use and for veterinary use, including light absorption
measuring apparatus and luminescence and fluorescence
measuring apparatus, pipetting devices and sampling devices,
dispensers, motorized syringe dilutors, pumps and dosing
apparatus for laboratories; disposable materials for use in
analytical apparatus and instruments for clinical diagnostic
use and for veterinary use; disposable pipette tips for use
in analytical apparatus and instruments for clinical
diagnostic use and for veterinary use. Installation, assembly, repair, maintenance, overhaul,
inspection and monitoring of automatic handling machines
[manipulators], scientific, optical, analytical, measuring,
dosing, checking and control apparatus and instruments,
pipetting and sampling devices, dispensers, motorized
syringe dilutors, pumps and dosing apparatus for laboratory
use, laboratory apparatus and instruments used for
extraction, microplate readers, imaging devices for
scientific use, microplate washers and genomics automation
devices; installation, assembly, repair, maintenance and
overhaul of robots and conveyors; providing information
relating to all the aforementioned services. Educational and training services, including provision of
data and materials for educational purposes for users of
laboratory apparatus; providing online education and
trainings; arranging and conducting instructional courses,
workshops and distance learning [training], in particular in
the field of laboratory apparatus; publication of printed
matter and electronic media, in particular training and
information material in the field of laboratory apparatus;
providing non-downloadable electronic publications online. Scientific and technological services, research services and
technical design services relating hereto; analysis and
research services; planning and design of laboratory
automation systems; order development of laboratory
automation equipment and analysis instruments; development
of computer software; providing temporary use of
non-downloadable software for controlling and monitoring
apparatus and instruments for laboratories, for controlling
and monitoring medical apparatus and for the analysis of
measurement results; providing temporary use of
non-downloadable or internet based software for use in the
automation of laboratories; providing internet platforms
[software]; hosting web portals; hosting computerized
data, files, applications and information; providing
computer programs in data networks; providing software
[Software as a service, SaaS]; Platform as a Service
[PaaS]; installation, repair and maintenance of software;
backup of electronic data; analysis and evaluation of
products and services with regard to possible future uses;
inspection of robots and conveyors for quality control
purposes.
68.
MIXING APPARATUS, MIXING SYSTEM AND METHOD FOR MIXING SUBSTANCES IN CLOSED CONTAINERS
A mixing apparatus containing a drive unit having a drive and a shaft that is pivotable about a pivot axis and is operatively connected to the drive. A pivotable receptacle is arranged on the shaft, where the pivot axis is oriented essentially horizontally, and the pivotable receptacle has a base plate and at least one retainer spaced therefrom, and the pivotable receptacle is configured in such a way that holders for containers can be inserted between the base plate and the at least one retainer in the direction of the pivot axis.
The invention relates to a pipetting device having tube with an opening at one end for suctioning or discharging a sample fluid, and can be operatively connected to a pressure generation device at the other end. A first electrode is formed on the pipetting device that forms a measuring capacitor together with a second electrode formed by at least one part of the sample fluid and that can be received in the tube and the measuring capacitor is operatively connected to a measuring unit, and the measuring unit is designed to determine a volume of the suctioned or discharged sample fluid according to the capacity of the measuring capacitor. The invention also relates to a fluid processing system having a pipetting device of this type, as well as a method for determining a processed fluid volume during pipetting with a pipetting device of this type.
G01F 23/263 - Indication ou mesure du niveau des liquides ou des matériaux solides fluents, p.ex. indication en fonction du volume ou indication au moyen d'un signal d'alarme en mesurant des variables physiques autres que les dimensions linéaires, la pression ou le poids, selon le niveau à mesurer, p.ex. par la différence de transfert de chaleur de vapeur ou d'eau en mesurant les variations de capacité ou l'inductance de condensateurs ou de bobines produites par la présence d'un liquide ou d'un matériau solide fluent dans des champs électriques ou électromagnétiques en mesurant les variations de capacité de condensateurs
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
G01D 5/241 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensible; Moyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminé; Transducteurs non spécialement adaptés à une variable particulière utilisant des moyens électriques ou magnétiques influençant la valeur d'un courant ou d'une tension en faisant varier la capacité par mouvement relatif d'électrodes de condensateur
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
B01L 9/00 - Dispositifs de support; Dispositifs de serrage
G01F 22/00 - Procédés ou appareils pour la mesure du volume des fluides ou des matériaux solides fluents, non prévus ailleurs
The invention relates to an incubation cassette (1) for reducing fluid evaporation out of wells of a microplate, comprising a frame (4) for receiving a microplate having wells, wherein the frame (4) has a central first opening (5) surrounded by an inner wall (6) and with dimensions designed for the insertion of a microplate, and the frame (4) also has an outer wall (8) running substantially parallel to the inner wall (6), which connects to the inner wall (6) via an intermediate base, such that a fluid reservoir (9) surrounding the first central opening (5) is formed by by the two walls (6, 8) and the intermediate base to receive a fluid. The incubation cassette (1) also comprises a floating body provided in the fluid reservoir (9), which can be brought into fluid contact with the fluid accommodated in the fluid reservoir (9) in such a way that the floating body experiences a buoyancy force in relation to the fluid level of the fluid accommodated in the fluid reservoir (9).
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
B01L 7/00 - Appareils de chauffage ou de refroidissement; Dispositifs d'isolation thermique
B01L 9/00 - Dispositifs de support; Dispositifs de serrage
G01F 23/68 - Indication ou mesure du niveau des liquides ou des matériaux solides fluents, p.ex. indication en fonction du volume ou indication au moyen d'un signal d'alarme par des flotteurs du type à flotteur libre en utilisant des moyens d'indication actionnés électriquement
Pipetting device for pipetting a liquid driven by a gaseous working medium, the pipetting device having at least one pipette connector adapted to attach a pipette at a connection opening at least one pressurizing and/or suctioning pressure source, a gas flow connection between said connection opening and at least one pressure source, a flow restriction defining at least a section of said gas flow connection, a first sensor configured to measure a quantity indicative of the temperature of the flow restriction. The invention is further directed to a gas flow connection element for a pipetting device and to a method of pipetting a liquid volume.
An incubation cassette for reducing liquid evaporation from wells of a microplate that has a frame for receiving a microplate having wells. The frame has a central first opening that is surrounded by an inner wall and the dimensions are designed for the placement of the microplate therein, and an outer wall extends substantially parallel to the inner wall and adjoins the inner wall via an intermediate bottom such that a liquid reservoir for holding a liquid is formed by the two walls and the intermediate bottom, the liquid reservoir surrounding the first central opening. At least a portion of the incubation cassette that forms the liquid reservoir is provided at least in part with at least one transparent portion (TA).
A combinable cavity tray for liquid handling is provided. The combinable cavity tray has at least one cavity for receiving a fluid and at least one passage for leading through a cavity of a second combinable cavity tray and/or for connecting to a pipetting apparatus. The at least one cavity of the combinable cavity tray is formed integrally. An assembly of combinable cavity trays having at least two combinable cavity trays, a method of manufacturing a combinable cavity tray and the use of a combinable cavity tray or of an assembly of combinable cavity trays for liquid handling are provided.
A device for determining a position and/or an extension of a drop in a position determination space, where the device has a camera having an objective and a beam splitter in the recording area of the camera, and the device is designed in such a way that light coming from the position determination space can enter the objective of the camera along a first light path as well as along a second light path, where light along the first light path can be reflected at a first reflector element in the direction of the beam splitter and can be transmitted through the beam splitter towards the objective, and where light along the second light path can be reflected at a second reflector element in the direction of the beam splitter and can be reflected at the beam splitter towards the objective.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
A device for controlling an optical recognition unit with the help of a capacitive filling level measurement in liquid containers having a sensor with a measuring electrode, a conductive base plate suitable for arranging at least one liquid container or a carrier unit having at least one receptacle for receiving a liquid container, a sensor electronics unit that is connected to the measuring electrode and the base plate adapted to determine a capacitance between the measuring electrode and base plate, an evaluation unit, and a control unit for controlling the optical recognition unit, is disclosed.
G01F 23/26 - Indication ou mesure du niveau des liquides ou des matériaux solides fluents, p.ex. indication en fonction du volume ou indication au moyen d'un signal d'alarme en mesurant des variables physiques autres que les dimensions linéaires, la pression ou le poids, selon le niveau à mesurer, p.ex. par la différence de transfert de chaleur de vapeur ou d'eau en mesurant les variations de capacité ou l'inductance de condensateurs ou de bobines produites par la présence d'un liquide ou d'un matériau solide fluent dans des champs électriques ou électromagnétiques
G01F 23/263 - Indication ou mesure du niveau des liquides ou des matériaux solides fluents, p.ex. indication en fonction du volume ou indication au moyen d'un signal d'alarme en mesurant des variables physiques autres que les dimensions linéaires, la pression ou le poids, selon le niveau à mesurer, p.ex. par la différence de transfert de chaleur de vapeur ou d'eau en mesurant les variations de capacité ou l'inductance de condensateurs ou de bobines produites par la présence d'un liquide ou d'un matériau solide fluent dans des champs électriques ou électromagnétiques en mesurant les variations de capacité de condensateurs
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
07 - Machines et machines-outils
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
37 - Services de construction; extraction minière; installation et réparation
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical products, namely, chemicals for use in industry and science; reagents for use in scientific apparatus and for manual sample processing in the nature of research purposes for biological and chemical analyses; reagents for research purposes; reagents for use in analytical apparatus other than for medical or veterinary purposes; Reagents for use in analytical apparatus for clinical laboratory diagnostics; immunoassay reagents for clinical laboratory diagnostics; reagents for use in clinical laboratory diagnostics, in particular for use in clinical laboratory nucleic acid-based diagnostics Reagents for use in analytical apparatus for clinical medical diagnostics; diagnostic reagents and analysis reagents for use for medical purposes in scientific and clinical laboratories; diagnostic reagents and analysis reagents for medical use; immunoassay reagents for clinical medical diagnostics; reagents for medical use; reagents for use in clinical medical diagnostics and for veterinary use, in particular for use in clinical medical or veterinary nucleic acid-based diagnostics; reagents for biological and chemical analyses for medical or veterinary purposes; reagents for use in analytical apparatus for medical or veterinary purposes; reagents for manual sample processing for biological and chemical analyses in the nature of medical use for the analysis of body fluids and tissue samples from humans, animals and plants Industrial robots; conveyors being machines; industrial robots, namely, automatic machines for collecting, distributing, transporting or positioning objects and solid, liquid or gaseous substances Pipetting devices and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for taking liquid samples for laboratory use; laboratory robots for laboratory automation and laboratory robots for the automation of analysis processes; laboratory apparatus and instruments used for extracting nucleic acids, proteins, hormones, drugs, metabolites and low weight (less than 2500 Daltons) molecules; microplate readers, namely, light absorption measuring apparatus and luminescence and fluorescence measuring apparatus; imaging devices for imaging of cells, cell colonies, biological tissues, protein arrays and nucleic acid arrays for scientific purposes; microplate washers; genomics automation devices, namely, thermocycling devices and sequencing library preparation devices; disposable pipette tips for laboratory use; disposable containers for reagents and samples in connection with pipetting devices; disposable materials, namely, microplates, lids for microplates, containers for bioprocessing and cell culturing applications, boxes and trays for disposable pipetting tips for use in laboratory apparatus; cell counting chambers for scientific use; laboratory consumables, namely, solid phase extraction plates; laboratory consumables, namely, solid phase extraction columns; disposable and reusable dispenser syringes for dilutors for laboratory use; structural parts of laboratory apparatus and instruments, namely, valves for dilutors; downloadable software for controlling laboratory apparatus and for controlling medical apparatus; downloadable software for evaluation of measurement results; downloadable software for image analysis; downloadable software for use in remote monitoring of laboratory apparatus; downloadable software for remote maintenance of laboratory apparatus; downloadable software for connecting laboratory apparatus; downloadable software for use in the automation of laboratories; downloadable training software for training in the fields of laboratory apparatus, instruments, equipment and laboratory automation; downloadable electronic information and publications in the nature of downloadable electronic data files and databases in the fields of laboratory apparatus, instruments, equipment and laboratory automation; recorded data files featuring information about laboratory apparatus, instruments, equipment and laboratory automation; downloadable educational course materials in the fields of laboratory apparatus, instruments, equipment and laboratory automation for training and education; laboratory robots; laboratory robots, namely, automatic machines for collecting, distributing, transporting or positioning objects and solid, liquid or gaseous substances; Analytical apparatus and instruments for clinical diagnostic laboratory use, namely, light absorption measuring apparatus and luminescence and fluorescence measuring apparatus, pipetting devices and sampling devices, dispensers, motorized syringe diluters, pumps and dosing apparatus for taking liquid samples; disposable materials, namely, microplates, lids for microplates, containers for bioprocessing and cell culturing applications, boxes and trays for disposable pipetting tips for use in analytical apparatus and instruments for clinical diagnostic laboratory use; disposable pipette tips for use in analytical apparatus and instruments for clinical diagnostic laboratory use Analytical apparatus and instruments for clinical medical diagnostic use and for veterinary use, namely, light absorption measuring apparatus and luminescence and fluorescence measuring apparatus, pipetting devices and sampling devices, dispensers, motorized syringe diluters, pumps and dosing apparatus for taking liquid samples; disposable materials, namely, microplates, lids for microplates, containers for bioprocessing and cell culturing applications, boxes and trays for disposable pipetting tips for use in analytical apparatus and instruments for clinical medical diagnostic use and for veterinary use; disposable pipette tips for use in analytical apparatus and instruments for clinical medical diagnostic use and for veterinary use; syringes for dilutors for clinical medical diagnostic use and for veterinary use Installation, repair, maintenance, overhaul of robots, conveyors, automatic handling machines in the nature of manipulators, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for laboratory use, laboratory apparatus and instruments used for extraction, microplate readers, imaging devices for scientific purposes, microplate washers and genomics automation devices; providing information in the field of all the aforementioned services Assembly of robots, conveyors, automatic handling machines in the nature of manipulators, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for laboratory use, laboratory apparatus and instruments used for extraction, microplate readers, imaging devices for scientific purposes, microplate washers and genomics automation devices; providing information in the field of all the aforementioned services Educational and training services, including provision of data and materials for educational purposes in the nature of distribution of training materials in connection therewith, namely, training for users in the use and operation of laboratory apparatus; providing online education and trainings, namely, classes, seminars, workshops in the field of laboratory apparatus, instruments, equipment and laboratory automation; arranging and conducting instructional courses, workshops and distance learning training, in particular in the field of laboratory apparatus; publication of printed matter and electronic media, in particular training and information material in the field of laboratory apparatus; providing online non-downloadable electronic publications in the nature of electronic datafiles and databases in the fields of laboratory apparatus, instruments, equipment and laboratory automation Scientific and technological services, namely, scientific laboratory services and research services as well as technical design services in the field of laboratory apparatus, laboratory instruments, analytical apparatus and analytical instruments; industrial analysis and research services in the field of chemistry and life sciences; planning and design of laboratory automation systems; order development of laboratory automation equipment and analysis instruments; development of computer software; providing temporary use of non-downloadable software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; providing temporary use of non-downloadable or internet based software for use in the automation of laboratories; providing a web hosting computer software platform for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; application service provider (ASP), namely, hosting computerized data, files, applications and information; providing computer programs in data networks, namely, on-line non-downloadable software programs for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results, provided via computer and communication networks; Software as a service (SAAS) services, namely, hosting software for use by others for use for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; Software as a service (SAAS) services featuring software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; Platform as a Service (PaaS) featuring computer software platforms for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; installation, repair and maintenance of software; backup of electronic data; analysis and evaluation of products and services to assure compliance with industry standards with regard to possible future uses; providing on-line non-downloadable software for controlling laboratory apparatus and for controlling medical apparatus; providing on-line non-downloadable software for evaluation of measurement results; providing on-line non-downloadable software for image analysis; providing on-line non-downloadable software for use in remote monitoring of laboratory apparatus; providing on-line non-downloadable software for remote maintenance of laboratory apparatus; providing on-line non-downloadable software for connecting laboratory apparatus; providing on-line non-downloadable software for use in the automation of laboratories; providing on-line non-downloadable computer software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement result; providing on-line non-downloadable application software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement result; providing on-line non-downloadable training software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement result; Remote monitoring of the functioning and use of robots, conveyors, automatic handling machines in the nature of manipulators, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for laboratory use, laboratory apparatus and instruments used for extraction, microplate readers, imaging devices for scientific purposes, microplate washers and genomics automation devices; Providing information in the field of remote monitoring of the functioning and use of robots, conveyors, automatic handling machines in the nature of manipulators, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for laboratory use, laboratory apparatus and instruments used for extraction, microplate readers, imaging devices for scientific purposes, microplate washers and genomics automation devices
A microplate processing device having at least one carriage with a first receptacle for microplates where the at least one carriage is movable in a first horizontal direction, and having at least one lift that is movable in a vertical direction, where the microplates can be removed from and supplied to the carriage, the carriage has a through-opening, the periphery, in the vertical projection, can at least in part be situated horizontally within the periphery of a microplate held in the carriage, and the lift has a second receptacle for microplates, the periphery, in the vertical projection, is situated within the periphery of the through-opening, where the second receptacle can be moved unhindered through the through-opening in the vertical direction.
G01N 35/02 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse
G01N 35/04 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse - Détails du transporteur
80.
Pipetting apparatus with a pipette tube and method for detecting a liquid within an intermediate section of a pipette tube
A pipetting apparatus and method capable of detecting a liquid within an intermediate section of a pipette tube of the pipetting apparatus. The intermediate section is located between an upper section of the pipette tube at which a first electrode is arranged and a lower section at which a second electrode is arranged. The first and second electrodes form a measurement capacitor and are operationally connected to an impedance measurement unit, which is adapted to detect whether liquid, such as a portion of a sample liquid or system liquid, is present within the intermediate section based on the measured impedance or change of impedance, e.g. an increase of the capacitance and/or a decrease of the resistance, of the measurement capacitor caused by a presence of the liquid within the intermediate section.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
81.
Pipetting apparatus, a liquid handling system and a method of controlling pipetting
A pipetting apparatus having a pipette tube with a first end provided with an opening for aspirating and/or dispensing of a sample fluid and a second end operationally connected to a pressure generating means. The pipetting apparatus has at least one measuring unit adapted to determine at least one measurement value of the sample fluid based on the aspirating and/or dispensing of the sample fluid and to provide a sample fluid measurement signal representative thereof to an output of the measuring unit. The pipetting apparatus also has a control circuit operationally coupled to the output of the measuring unit and the input of the pressure generating means, the control circuit is configured to control said pressure generating device based on the sample fluid measurement signal.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
G01N 11/04 - Recherche des propriétés d'écoulement des matériaux, p.ex. la viscosité, la plasticité; Analyse des matériaux en déterminant les propriétés d'écoulement en mesurant l'écoulement du matériau à travers un passage étroit, p.ex. un tube, une ouverture
G01N 13/02 - Recherche de la tension superficielle des liquides
A cover (1) for a fluid container (4) comprising an essentially plane cover plate (10) for closing at least one opening of at least one fluid container (4) and at least two ports (11,12), wherein each port (11,12) comprises a trough channel (110,120) extending through the entire thickness of the cover plate (10), wherein a fluid impermeable first membrane (2) is arranged over the entire cross section of the through channel (110) of the first port (11) and wherein an at least gas permeable second membrane (3;30) is arranged over the entire cross section of the through channel (120) of the second port (12).
A displacement device for displacing a displacement volume is provided. The device comprises a first fluid space and a second fluid space. A first piston is arranged in a movable manner within the first fluid space. The first fluid space is connectable to a pipetting device. The first piston is actuatable by an actuation volume of air or of liquid provided by the pipetting device. A second piston is arranged in a movable manner within the second fluid space. The second piston is constructed to displace a displacement volume of a fluid located within the second fluid space when the second piston is actuated. The second piston is actuated in dependence on the first piston that is actuated by the actuation volume. The actuation volume is different from the displacement volume. Furthermore, a pipetting system comprising a displacement device and a method of displacing a displacement volume are provided.
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
A method for generating a control program for a laboratory automation device includes: receiving video data displaying a work area of a laboratory assistant, the work area containing a hand-held pipette and containers for receiving a liquid; detecting openings of the containers in the video data and determining positions of the openings; detecting a pipette tip of the hand-held pipette in the video data and determining a movement of the tip; and generating the control program for the laboratory automation device from the movement of the pipette tip with respect to the positions of the openings, wherein the control program is adapted for moving a pipetting arm with a robot pipette of the laboratory automation device with respect to containers of the laboratory automation device accordingly to the movement of the hand-held pipette in the work area.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
G05B 19/042 - Commande à programme autre que la commande numérique, c.à d. dans des automatismes à séquence ou dans des automates à logique utilisant des processeurs numériques
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge comprises a liquid input port (19') for introducing an input liquid into an internal gap of the cartridge, the input liquid providing for at least one droplet (23), directly or via a liquid separation process within the internal gap, and the internal gap comprising at least one hydrophobic surface, at least one processing zone (78) for processing samples (80) located in the processing zone (78), and a delivery zone (74) for delivering the at least one droplet (23) from the liquid input port (19') to the at least one processing zone (78). The delivery zone (74) is configured to provide a repeating pattern of interacting electrowetting force for simultaneously transporting the at least one droplet (23) within the delivery zone (74).
A cartridge (2) for use in an electrowetting sample processing system, the cartridge (2) comprising at least one inlet port (19') for introducing an input liquid (60, 61) in an internal gap (6) of the cartridge (2), wherein the gap (6) comprises at least one hydrophobic surface (17) and is configured to provide an electrowetting induced movement of a microfluidic droplet (23) of input liquid (60, 61), wherein the input liquid (60, 61) comprises a carrier liquid (60) and a processing liquid (61) and the gap (6) comprises a capture zone that is configured to capture at least a part of the processing liquid (60,61) as a microfluidic droplet (23) by use of electrowetting force and the gap (6) further comprises a transfer zone that is configured to provide a passage for the carrier liquid (60) next to the microfluidic droplet (23), while processing liquid (61) is captured in the capture zone (62).
A cartridge (2) for use in an electrowetting sample processing system, the cartridge comprising one or more inlet ports (19') for introducing an input liquid into an internal gap (6) of the cartridge (2), which comprises at least one hydrophobic surface (17) for enabling an electrowetting induced movement of multiple microfluidic droplets (23) separated from the input liquid. The cartridge (2) further comprises at least one outlet port (80) that is operably connected to the inlet port (19') for providing a liquid flow through the cartridge (2), if a liquid driving force, in particular an electrowetting force or a pressure force, is applied to at least a part of the input liquid.
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
Produits et services
Biochemical reagents for scientific or research purposes, in
particular for use related to nucleic acid sequencing;
biochemical reagents for scientific or research purposes, in
particular for use in genomic research; reagents for the
derivatization of bio-molecules for scientific or research
purposes, in particular for use related to mass
spectroscopy. Biochemical reagents for clinical-diagnostic use and use in
veterinary medicine, in particular for use related to
nucleic acid sequencing; biochemical reagents for
clinical-diagnostic use and use in veterinary medicine, in
particular for use in clinical or veterinary nucleic
acid-based diagnostics; reagents for the derivatization of
bio-molecules for clinical-diagnostic use and use in
veterinary medicine, in particular for use related to mass
spectroscopy. Scientific, optical, analytical, metering, dosing and
control apparatus and instruments; scientific apparatus and
instruments, namely absorption measuring devices,
fluorescence measuring devices, pipetting devices and
sampling devices for taking liquid samples, all the
aforementioned products for laboratory use; software for
the automation of procedures related to genomic research and
genome analysis; software for the automation of procedures
related to sequencing of nucleic acids; software for the
automation of procedures related to extraction,
derivatization and concentration of bio-molecules for mass
spectroscopy. Analytical apparatus and instruments for clinical-diagnostic
use and veterinary diagnostic use, namely, absorption
measuring apparatus, fluorescence measuring apparatus,
pipetting apparatus and sampling devices for taking liquid
samples; all the aforementioned products for clinical
diagnostic purposes.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
07 - Machines et machines-outils
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
37 - Services de construction; extraction minière; installation et réparation
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Produits chimiques à usage industriel et scientifique; réactifs pour l'analyse biologique et chimique; réactifs pour la recherche; réactifs pour les instruments d'analyse.
(2) Réactifs à utiliser dans les appareils analytiques pour le diagnostic clinique; réactifs de diagnostic et d'analyse à utiliser à des fins médicales dans les laboratoires scientifiques et cliniques; réactifs de diagnostic et d'analyse à utiliser à des fins médicales; réactifs pour immunotests pour le diagnostic clinique; réactifs à utiliser à des fins médicales; réactifs à usage diagnostique de nature clinique et pour l'usage vétérinaire, en particulier pour l'usage dans le diagnostique de nature clinique ou vétérinaire à base d'acides nucléiques.
(3) Robots; transporteurs [convoyeurs]; manipulateurs industriels [machines]; robots, à savoir appareils automatiques pour la collection, la distribution, le transport, le positionnement d'objets et de substances solides, liquides et gazéiformes.
(4) Appareils et instruments scientifiques, optiques, analytiques, de mesurage, de dosage, de contrôle, d'inspection, en particulier pour usage en laboratoires; appareils et instruments d'analyse à usage scientifique ou non-médical; dispositifs de pipetage et dispositifs d'échantillonnage, distributeurs, diluteurs à seringues motorisées, pompes et appareils de dosage pour laboratoires; robots pour l'automatisation de laboratoires et robots pour l'automatisation des processus d'analyses; appareils et instruments de laboratoire pour l'extraction; lecteurs de microplaques, à savoir appareils de mesure d'absorption, des appareils de mesure de luminescence et des appareils de mesure de fluorescence; appareils d'imagerie à usage scientifique; laveurs de microplaques; appareils d'automatisation de la génomique; embouts jetables de pipettes de laboratoire; récipients jetables pour réactifs et échantillons en relation avec dispositifs de pipetage; microplaques; matériaux jetables pour appareils de laboratoire; chambres pour calculer des cellules à usage scientifique; plaques d'extraction; colonnes d'extraction; seringues pour diluteurs; valves pour diluteurs; logiciels pour le contrôle des appareils de laboratoire et pour le contrôle des appareils médicaux; logiciels pour l'évaluation des résultats de mesure; logiciels pour l'analyse d'images; logiciels pour ordinateurs; logiciels d'applications; logiciels téléchargeables à partir de réseaux et de nuages informatiques; logiciels pour la surveillance à distance des appareils de laboratoire; logiciels pour la maintenance à distance des appareils de laboratoire; logiciels pour la connexion des appareils de laboratoire; logiciels pour l'automatisation des laboratoires; logiciels de formation; informations et publications électroniques téléchargeables; fichiers de données enregistrées; supports de cours téléchargeables pour la formation et l'éducation.
(5) Appareils et instruments analytiques à usage diagnostique de nature clinique et à usage vétérinaire, y compris appareils de mesure d'absorption, appareils de mesure de luminescence et appareils de mesure de fluorescence, dispositifs de pipetage et dispositifs d'échantillonnage, distributeurs, diluteurs à seringues motorisées, pompes et appareils de dosage pour laboratoires; matériaux jetables à utiliser dans les appareils et instruments analytiques à usage diagnostique de nature clinique et à usage vétérinaire; embouts jetables de pipettes à utiliser dans les appareils et instruments analytiques à usage diagnostique de nature clinique et à usage vétérinaire. (1) Installation, montage, réparation, entretien, révision, inspection et surveillance des manipulateurs industriels [machines], appareils et instruments scientifiques, optiques, analytiques, de mesurage, de dosage, de contrôle, d'inspection, dispositifs de pipetage et dispositifs d'échantillonnage, distributeurs, diluteurs à seringues motorisées, pompes et appareils de dosage pour laboratoires, appareils et instruments de laboratoire pour l'extraction, lecteurs de microplaques, appareils d'imagerie à usage scientifique, laveurs de microplaques et appareils d'automatisation de la génomique; installation, montage, réparation, entretien et révision de robots et transporteurs [convoyeurs]; fourniture d'informations relatives à tous les services précités.
(2) Services d'éducation et de formation, y compris la mise à disposition de données et de matériel à des fins éducatives pour les utilisateurs d'appareils de laboratoire; fourniture d'éducation et de formation en ligne; organisation et prestation de cours, d'ateliers et de formation à distance, en particulier dans le domaine d'appareils de laboratoire; publication et édition de documents imprimés et de médias électroniques, en particulier de matériel éducatif et d'information dans le domaine d'appareils de laboratoire; mise à disposition en ligne de publications électroniques non téléchargeables.
(3) Services scientifiques et technologiques et services de recherches ainsi que services de conception technique y relatifs; services d'analyses et de recherches; planification et conception de systèmes automatisés de laboratoire; développement sur mesure d'équipements d'automatisation de laboratoire et d'instruments analytiques; développement de logiciels informatiques; mise à disposition temporaire de logiciels non téléchargeables pour la commande et la surveillance d'appareils et d'instruments de laboratoire, pour le contrôle et la surveillance d'appareils médicaux et pour l'analyse de résultats de mesures; mise à disposition temporaire de logiciels non téléchargeables ou basés sur Internet destinés à l'automatisation de laboratoires; hébergement de plates-formes Internet [logiciels]; hébergement de portails Web; hébergement de données informatisées, fichiers, applications et informations; mise à disposition de programmes informatiques dans des réseaux de données; mise à disposition de logiciels [Logiciel-service SaaS]; plateforme informatique en tant que service [PaaS]; installation, réparation et maintenance de logiciels; sauvegarde de données électroniques; analyse et évaluation des produits et services concernant leur éventuelle utilisation ultérieure; inspection de robots et transporteurs [convoyeurs] à des fins de contrôle de qualité.
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
07 - Machines et machines-outils
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
37 - Services de construction; extraction minière; installation et réparation
40 - Traitement de matériaux; recyclage, purification de l'air et traitement de l'eau
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Chemical products, namely, chemicals for use in industry and science; reagents for use in scientific apparatus and for manual sample processing in the nature of research purposes for biological and chemical analyses; reagents for research purposes; reagents for use in analytical apparatus other than for medical or veterinary purposes; Reagents for use in analytical apparatus for clinical laboratory diagnostics; immunoassay reagents for clinical laboratory diagnostics; reagents for use in clinical laboratory diagnostics, in particular for use in clinical laboratory nucleic acid-based diagnostics Reagents for use in analytical apparatus for clinical medical diagnostics; diagnostic reagents and analysis reagents for use for medical purposes in scientific and clinical laboratories; diagnostic reagents and analysis reagents for medical use; immunoassay reagents for clinical medical diagnostics; reagents for medical use; reagents for use in clinical medical diagnostics and for veterinary use, in particular for use in clinical medical or veterinary nucleic acid-based diagnostics; reagents for biological and chemical analyses for medical or veterinary purposes; reagents for use in analytical apparatus for medical or veterinary purposes; reagents for manual sample processing for biological and chemical analyses in the nature of medical use for the analysis of body fluids and tissue samples from humans, animals and plants Industrial robots; conveyors being machines; industrial robots, namely, automatic machines for collecting, distributing, transporting or positioning objects and solid, liquid or gaseous substances Pipetting devices and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for taking liquid samples for laboratory use; laboratory robots for laboratory automation and laboratory robots for the automation of analysis processes; laboratory apparatus and instruments used for extracting nucleic acids, proteins, hormones, drugs, metabolites and low weight (less than 2500 Daltons) molecules; microplate readers, namely, light absorption measuring apparatus and luminescence and fluorescence measuring apparatus; imaging devices for imaging of cells, cell colonies, biological tissues, protein arrays and nucleic acid arrays for scientific purposes; microplate washers; genomics automation devices, namely, thermocycling devices and sequencing library preparation devices; disposable pipette tips for laboratory use; disposable containers for reagents and samples in connection with pipetting devices; disposable materials, namely, microplates, lids for microplates, containers for bioprocessing and cell culturing applications, boxes and trays for disposable pipetting tips for use in laboratory apparatus; cell counting chambers for scientific use; laboratory consumables, namely, solid phase extraction plates; laboratory consumables, namely, solid phase extraction columns; disposable and reusable dispenser syringes for dilutors for laboratory use; structural parts of laboratory apparatus and instruments, namely, valves for dilutors; downloadable software for controlling laboratory apparatus and for controlling medical apparatus; downloadable software for evaluation of measurement results; downloadable software for image analysis; downloadable software for use in remote monitoring of laboratory apparatus; downloadable software for remote maintenance of laboratory apparatus; downloadable software for connecting laboratory apparatus; downloadable software for use in the automation of laboratories; downloadable training software for training in the fields of laboratory apparatus, instruments, equipment and laboratory automation; downloadable electronic information and publications in the nature of downloadable electronic data files and databases in the fields of laboratory apparatus, instruments, equipment and laboratory automation; recorded data files featuring information about laboratory apparatus, instruments, equipment and laboratory automation; downloadable educational course materials in the fields of laboratory apparatus, instruments, equipment and laboratory automation for training and education; laboratory robots; laboratory robots, namely, automatic machines for collecting, distributing, transporting or positioning objects and solid, liquid or gaseous substances; Analytical apparatus and instruments for clinical diagnostic laboratory use, namely, light absorption measuring apparatus and luminescence and fluorescence measuring apparatus, pipetting devices and sampling devices, dispensers, motorized syringe diluters, pumps and dosing apparatus for taking liquid samples; disposable materials, namely, microplates, lids for microplates, containers for bioprocessing and cell culturing applications, boxes and trays for disposable pipetting tips for use in analytical apparatus and instruments for clinical diagnostic laboratory use; disposable pipette tips for use in analytical apparatus and instruments for clinical diagnostic laboratory use Analytical apparatus and instruments for clinical medical diagnostic use and for veterinary use, namely, light absorption measuring apparatus and luminescence and fluorescence measuring apparatus, pipetting devices and sampling devices, dispensers, motorized syringe diluters, pumps and dosing apparatus for taking liquid samples; disposable materials, namely, microplates, lids for microplates, containers for bioprocessing and cell culturing applications, boxes and trays for disposable pipetting tips for use in analytical apparatus and instruments for clinical medical diagnostic use and for veterinary use; disposable pipette tips for use in analytical apparatus and instruments for clinical medical diagnostic use and for veterinary use; syringes for dilutors for clinical medical diagnostic use and for veterinary use Installation, repair, maintenance, overhaul of robots, conveyors, automatic handling machines in the nature of manipulators, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for laboratory use, laboratory apparatus and instruments used for extraction, microplate readers, imaging devices for scientific purposes, microplate washers and genomics automation devices; providing information in the field of all the aforementioned services Assembly of robots, conveyors, automatic handling machines in the nature of manipulators, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for laboratory use, laboratory apparatus and instruments used for extraction, microplate readers, imaging devices for scientific purposes, microplate washers and genomics automation devices; providing information in the field of all the aforementioned services Educational and training services, including provision of data and materials for educational purposes in the nature of distribution of training materials in connection therewith, namely, training for users in the use and operation of laboratory apparatus; providing online education and trainings, namely, classes, seminars, workshops in the field of laboratory apparatus, instruments, equipment and laboratory automation; arranging and conducting instructional courses, workshops and distance learning training, in particular in the field of laboratory apparatus; publication of printed matter and electronic media, in particular training and information material in the field of laboratory apparatus; providing online non-downloadable electronic publications in the nature of electronic datafiles and databases in the fields of laboratory apparatus, instruments, equipment and laboratory automation Scientific and technological services, namely, scientific laboratory services and research services as well as technical design services in the field of laboratory apparatus, laboratory instruments, analytical apparatus and analytical instruments; industrial analysis and research services in the field of chemistry and life sciences; planning and design of laboratory automation systems; order development of laboratory automation equipment and analysis instruments; development of computer software; providing temporary use of non-downloadable software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; providing temporary use of non-downloadable or internet based software for use in the automation of laboratories; providing a web hosting computer software platform for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; application service provider (ASP), namely, hosting computerized data, files, applications and information; providing computer programs in data networks, namely, on-line non-downloadable software programs for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results, provided via computer and communication networks; Software as a service (SAAS) services, namely, hosting software for use by others for use for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; Software as a service (SAAS) services featuring software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; Platform as a Service (PaaS) featuring computer software platforms for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement results; installation, repair and maintenance of software; backup of electronic data; analysis and evaluation of products and services to assure compliance with industry standards with regard to possible future uses; providing on-line non-downloadable software for controlling laboratory apparatus and for controlling medical apparatus; providing on-line non-downloadable software for evaluation of measurement results; providing on-line non-downloadable software for image analysis; providing on-line non-downloadable software for use in remote monitoring of laboratory apparatus; providing on-line non-downloadable software for remote maintenance of laboratory apparatus; providing on-line non-downloadable software for connecting laboratory apparatus; providing on-line non-downloadable software for use in the automation of laboratories; providing on-line non-downloadable computer software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement result; providing on-line non-downloadable application software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement result; providing on-line non-downloadable training software for controlling and monitoring apparatus and instruments for laboratories, for controlling and monitoring medical apparatus and for the analysis of measurement result; Remote monitoring of the functioning and use of robots, conveyors, automatic handling machines in the nature of manipulators, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for laboratory use, laboratory apparatus and instruments used for extraction, microplate readers, imaging devices for scientific purposes, microplate washers and genomics automation devices; Providing information in the field of remote monitoring of the functioning and use of robots, conveyors, automatic handling machines in the nature of manipulators, scientific, optical, analytical, measuring, dosing, checking and control apparatus and instruments, pipetting and sampling devices, dispensers, motorized syringe dilutors, pumps and dosing apparatus for laboratory use, laboratory apparatus and instruments used for extraction, microplate readers, imaging devices for scientific purposes, microplate washers and genomics automation devices
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
07 - Machines et machines-outils
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
37 - Services de construction; extraction minière; installation et réparation
41 - Éducation, divertissements, activités sportives et culturelles
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
(1) Produits chimiques à usage industriel et scientifique; réactifs pour l'analyse biologique et chimique; réactifs pour la recherche; réactifs pour les instruments d'analyse.
(2) Réactifs à utiliser dans les appareils analytiques pour le diagnostic clinique; réactifs de diagnostic et d'analyse à utiliser à des fins médicales dans les laboratoires scientifiques et cliniques; réactifs de diagnostic et d'analyse à utiliser à des fins médicales; réactifs pour immunotests pour le diagnostic clinique; réactifs à utiliser à des fins médicales; réactifs à usage diagnostique de nature clinique et pour l'usage vétérinaire, en particulier pour l'usage dans le diagnostique de nature clinique ou vétérinaire à base d'acides nucléiques.
(3) Robots; transporteurs [convoyeurs]; manipulateurs industriels [machines]; robots, à savoir appareils automatiques pour la collection, la distribution, le transport, le positionnement d'objets et de substances solides, liquides et gazéiformes.
(4) Appareils et instruments scientifiques, optiques, analytiques, de mesurage, de dosage, de contrôle, d'inspection, en particulier pour usage en laboratoires; appareils et instruments d'analyse à usage scientifique ou non-médical; dispositifs de pipetage et dispositifs d'échantillonnage, distributeurs, diluteurs à seringues motorisées, pompes et appareils de dosage pour laboratoires; robots pour l'automatisation de laboratoires et robots pour l'automatisation des processus d'analyses; appareils et instruments de laboratoire pour l'extraction; lecteurs de microplaques, à savoir appareils de mesure d'absorption, des appareils de mesure de luminescence et des appareils de mesure de fluorescence; appareils d'imagerie à usage scientifique; laveurs de microplaques; appareils d'automatisation de la génomique; embouts jetables de pipettes de laboratoire; récipients jetables pour réactifs et échantillons en relation avec dispositifs de pipetage; microplaques; matériaux jetables pour appareils de laboratoire; chambres pour calculer des cellules à usage scientifique; plaques d'extraction; colonnes d'extraction; seringues pour diluteurs; valves pour diluteurs; logiciels pour le contrôle des appareils de laboratoire et pour le contrôle des appareils médicaux; logiciels pour l'évaluation des résultats de mesure; logiciels pour l'analyse d'images; logiciels pour ordinateurs; logiciels d'applications; logiciels téléchargeables à partir de réseaux et de nuages informatiques; logiciels pour la surveillance à distance des appareils de laboratoire; logiciels pour la maintenance à distance des appareils de laboratoire; logiciels pour la connexion des appareils de laboratoire; logiciels pour l'automatisation des laboratoires; logiciels de formation; informations et publications électroniques téléchargeables; fichiers de données enregistrées; supports de cours téléchargeables pour la formation et l'éducation.
(5) Appareils et instruments analytiques à usage diagnostique de nature clinique et à usage vétérinaire, y compris appareils de mesure d'absorption, appareils de mesure de luminescence et appareils de mesure de fluorescence, dispositifs de pipetage et dispositifs d'échantillonnage, distributeurs, diluteurs à seringues motorisées, pompes et appareils de dosage pour laboratoires; matériaux jetables à utiliser dans les appareils et instruments analytiques à usage diagnostique de nature clinique et à usage vétérinaire; embouts jetables de pipettes à utiliser dans les appareils et instruments analytiques à usage diagnostique de nature clinique et à usage vétérinaire. (1) Installation, montage, réparation, entretien, révision, inspection et surveillance des manipulateurs industriels [machines], appareils et instruments scientifiques, optiques, analytiques, de mesurage, de dosage, de contrôle, d'inspection, dispositifs de pipetage et dispositifs d'échantillonnage, distributeurs, diluteurs à seringues motorisées, pompes et appareils de dosage pour laboratoires, appareils et instruments de laboratoire pour l'extraction, lecteurs de microplaques, appareils d'imagerie à usage scientifique, laveurs de microplaques et appareils d'automatisation de la génomique; installation, montage, réparation, entretien et révision de robots et transporteurs [convoyeurs]; fourniture d'informations relatives à tous les services précités.
(2) Services d'éducation et de formation, y compris la mise à disposition de données et de matériel à des fins éducatives pour les utilisateurs d'appareils de laboratoire; fourniture d'éducation et de formation en ligne; organisation et prestation de cours, d'ateliers et de formation à distance, en particulier dans le domaine d'appareils de laboratoire; publication et édition de documents imprimés et de médias électroniques, en particulier de matériel éducatif et d'information dans le domaine d'appareils de laboratoire; mise à disposition en ligne de publications électroniques non téléchargeables.
(3) Services scientifiques et technologiques et services de recherches ainsi que services de conception technique y relatifs; services d'analyses et de recherches; planification et conception de systèmes automatisés de laboratoire; développement sur mesure d'équipements d'automatisation de laboratoire et d'instruments analytiques; développement de logiciels informatiques; mise à disposition temporaire de logiciels non téléchargeables pour la commande et la surveillance d'appareils et d'instruments de laboratoire, pour le contrôle et la surveillance d'appareils médicaux et pour l'analyse de résultats de mesures; mise à disposition temporaire de logiciels non téléchargeables ou basés sur Internet destinés à l'automatisation de laboratoires; hébergement de plates-formes Internet [logiciels]; hébergement de portails Web; hébergement de données informatisées, fichiers, applications et informations; mise à disposition de programmes informatiques dans des réseaux de données; mise à disposition de logiciels [Logiciel-service SaaS]; plateforme informatique en tant que service [PaaS]; installation, réparation et maintenance de logiciels; sauvegarde de données électroniques; analyse et évaluation des produits et services concernant leur éventuelle utilisation ultérieure; inspection de robots et transporteurs [convoyeurs] à des fins de contrôle de qualité.
94.
Position detector and method for 3D position determination
A position detector for generating 3D position information of an object in a position determination space for the object. The position detector has a camera with a lens and an image sensor that defines an imaging area with one first light deflecting element arranged in the imaging area as the camera and the at least one light deflecting element are adapted to simultaneously produce on the image sensor at least two images of the position determination space, a first image being produced by light beams deflected at the first light deflecting element, the at least two images differ with respect to the viewing direction of the position determination space.
G01B 11/00 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques
G01B 11/02 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur
G01B 11/03 - Dispositions pour la mesure caractérisées par l'utilisation de techniques optiques pour mesurer la longueur, la largeur ou l'épaisseur en mesurant les coordonnées de points
A rotary valve comprises a stator member with a planar stator face, the stator member having a plurality of stator channels for conducting a fluid and a rotor member with a planar rotor face facing and in contact with the stator face, the rotor member having at least one rotor channel. The rotor member is rotatable with respect to the stator member, such that in specific rotor positions, the rotor channel interconnects two of the stator channels, such that the stator channels are in fluid communication. One of the stator member and the rotor member is made of ceramics material, wherein the other one of the stator member and the rotor member is made of a polymer material. The ceramics material is coated with a diamond-like carbon (DLC).
F16K 11/074 - Soupapes ou clapets à voies multiples, p.ex. clapets mélangeurs; Raccords de tuyauteries comportant de tels clapets ou soupapes; Aménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des tiroirs à éléments de fermeture articulés à pivot à faces d'obturation planes
F16K 25/00 - SOUPAPES; ROBINETS; VANNES; COMMANDES À FLOTTEURS; DISPOSITIFS POUR VENTILER OU AÉRER - Détails constitutifs relatifs au contact entre corps de soupapes ou de clapets et leurs sièges
F16K 31/04 - Moyens de fonctionnement; Dispositifs de retour à la position de repos magnétiques utilisant un moteur
A gripper having a mechanical coupling that can be connected to a pipetting tube, at least one fluid channel extends from the coupling and a negative pressure can be transmitted, the gripper having at least one suction cup that is connected to the coupling through the at least one fluid channel as a result of which the negative pressure can be transmitted from the coupling to the at least one suction cup, and the at least one suction cup in the intended use position of the gripper is aligned such that a rim of a suction cup of the at least one suction cup is aligned in a substantially vertical plane.
G01N 35/00 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet
G01N 35/04 - Analyse automatique non limitée à des procédés ou à des matériaux spécifiés dans un seul des groupes ; Manipulation de matériaux à cet effet en utilisant une série de récipients à échantillons déplacés par un transporteur passant devant un ou plusieurs postes de traitement ou d'analyse - Détails du transporteur
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
09 - Appareils et instruments scientifiques et électriques
10 - Appareils et instruments médicaux
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Biochemical reagents for scientific or research purposes, in particular for use related to nucleic acid sequencing; Biochemical reagents for scientific or research purposes, in particular for use in genomic research; Reagents for the derivatization of bio-molecules for scientific or research purposes, in particular for use related to mass spectroscopy; Biochemical reagents for clinical-diagnostic laboratory or research use, in particular for use related to nucleic acid sequencing; Biochemical reagents for clinical-diagnostic laboratory or research use, in particular for use in laboratory or research clinical nucleic acid-based diagnostics; Reagents for the derivatization of bio-molecules for clinical-diagnostic laboratory or research use, in particular for use related to mass spectroscopy Biochemical reagents for clinical medical diagnostic use and use in veterinary medicine, in particular for use related to nucleic acid sequencing; Biochemical reagents for clinical medical diagnostic use and use in veterinary medicine, in particular for use in clinical medical or veterinary nucleic acid-based diagnostics; Reagents for the derivatization of bio-molecules for clinical medical diagnostic use and use in veterinary medicine, in particular for use related to mass spectroscopy Scientific apparatus and instruments, namely, absorption measuring devices, fluorescence measuring devices, pipetting devices and sampling devices for taking liquid samples; all the aforementioned products for laboratory use; Recorded and downloadable software for the automation of workflows related to genomic research and genome analysis; Recorded and downloadable software for the automation of workflows related to sequencing of nucleic acids; Recorded and downloadable software for the automation of workflows related to extraction, derivatization and concentration of biomolecules for mass spectroscopy; Analytical apparatus and instruments for clinical-diagnostic laboratory use, namely, absorption measuring apparatus, fluorescence measuring apparatus, pipetting apparatus and sampling devices for taking liquid samples; all the aforementioned products for clinical diagnostical laboratory purposes Analytical apparatus and instruments for clinical medical diagnostic use and veterinary diagnostic use, namely, absorption measuring apparatus, fluorescence measuring apparatus, pipetting apparatus and sampling devices for taking liquid samples; all the aforementioned products for clinical medical diagnostical purposes Providing on-line non-downloadable software for the automation of workflows related to genomic research and genome analysis; Providing on-line non-downloadable software for the automation of workflows related to sequencing of nucleic acids; Providing on-line non-downloadable software for the automation of workflows related to extraction, derivatization and concentration of bio-molecules for mass spectroscopy
A hollow needle for piercing a closure of a sample vessel, wherein the hollow needle has a cylindrical hollow profile extending along a longitudinal axis and having a tip at a first end thereof, where the hollow needle has a first section that has a tip and a second section that has a larger diameter than the first section, and a transition between the first section and the second section has at least one cutting edge that extends from the first section to the second section.
A method for classifying liquid handling procedures comprises, such as pipetting procedures occurring during laboratory automated analyses: receiving measurement data (56) encoding a measurement curve (28, 30, 32) of measurements over time during at least a part of a liquid handling procedure; inputting the measurement data (56) into a neural network (57); and calculating at least one quality value (74, 86) for the liquid handling procedure with the neural network (57). The neural network allows to classify whether a liquid handling procedure is normal or abnormal, e.g. clotting in the line, presence of air or bubbles, etc...
G01N 35/10 - Dispositifs pour transférer les échantillons vers, dans ou à partir de l'appareil d'analyse, p.ex. dispositifs d'aspiration, dispositifs d'injection
