THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig
Fretz, Megan
Walles, Joshua
Abrégé
Process for treating metal such as aluminum and its alloys to prevent corrosion which comprises coating the metal with a chromium-free conversion composition containing effective amounts of metal fluorozirconates and carboxylic metal salts. The process comprises coating the metal with a chromium-free conversion coating containing from about 4 to 8 grams of a metal fluorozirconate per liter of the chromium-free conversion coating and from about 0.5 to 5.0 grams of at least one carboxylic metal salt per liter of the chromium-free conversion coating. The incorporation of corrosion inhibitor salts with at least one carboxylate anion and a variety of cations in conversion coatings for aluminum and aluminum alloys to enhance corrosion performance and paint adhesion.
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Merril, Carl
Biswas, Biswajit
Abrégé
Vaccines directed to the SARS-CoV-2 antigen, methods of administering and/or treating a subject (including prophylactic treatment) infected and/or at risk of being infected with SARS-CoV-2. A transdermal membrane comprising a non-infectious icosahedral phage vaccine displaying a SARS-CoV-2 antigen is described wherein the membrane is stable at room temperature for greater than 3 months and uses thereof to vaccinate a subject against the SARS-CoV-2 antigen.
UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Sorna, Mark
Yates, Jacob
Schuyler, Nathan
Ruiz, Jose
Abrégé
A filtration mask protects the wearer against airborne hazards. The mask is reusable and may be used in a number of configurations. The mask includes filters located to the side and beneath the line of sight of the wearer. The filters may be tailored to the use and type of environmental hazard.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Hughey, Scott
Booth, Gregory, James
Cole, Jacob, H.
Abrégé
A medical ventilator for delivering a flow oxygen-containing gas to the airway of a patient, which comprises an oxygen containing gas source, a controlled valve arrangement for intermittent feeding of breathing gas from the gas source and expandable pressure chamber for to achieve desired tidal volume.
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Liu, Yang
Savarino, Stephen
Abrégé
Antigen binding proteins that interact with class 5 ETEC adhesins, compositions comprising said antigen binding proteins, and methods of preventing or treating ETEC related disorders in a subject in need thereof comprising administering to said subject a therapeutically effective amount of one or more of said compositions are described.
THE UNITED STATES OF AMERICA AS represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Biswas, Biswajit
Bishop-Lilly, Kimberly
Abrégé
The invention relates to a method of preventing, ameliorating or treating disease caused by coronavirus in a subject in need thereof comprising administering to the subject an immunogenic composition comprising a therapeutically effective amount of one or more bacteriophage displaying on its capsid one or more antigenic coronavirus peptides fused with one or more bacteriophage capsid proteins (PVPs).
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig
Grieve, Alan
Westbrook, Alexander
Abrégé
This invention is directed to a process of coating metal in a trivalent chromium conversion-electrolyte coating wherein the metal anode or cathode is subjected to a current density ranging up to about 3.0 amperes per square foot for a period ranging up to 60 minutes.
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE (USA)
THE GOVERNMENT OF THE UNITED STATES, as represented by THE SECRETARY OF THE ARMY (USA)
THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Bradley, Matthew, J.
Elster, Eric, A.
Khatri, Vivek
Oh, John, S.
Schobel, Seth, A.
Abrégé
The present disclosure describes methods and systems for predicting if a subject has an increased risk of having or developing venous thromboembolism, including prior to the detection of symptoms thereof and/or prior to onset of any detectable symptoms thereof. The present disclosure also describes a method of generating a model for predicting venous thromboembolism.
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Arafat, El Sayed
Abrégé
Invention relates to corrosion-inhibiting compositions and the process of using said compositions to protect metal from corrosion. The compositions comprise of sulfonates, a carboxylic-sulfonic acid metal complex, antioxidants, fluorinated copolymers, hydrophobic silanes and siloxane additives and solvent.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (USA)
Inventeur(s)
Jiang, Le
Chao, Chien-Chung
Ching, Wei-Mei
Abrégé
Methods, primers, and kits for detecting Anaplasma phagocytophilum (A. phagocytophilum ) by amplification of a multi-copy DNA target sequence found within the msp2 gene of A. phagocytophilum are disclosed. Methods for treating A. phagocytophilum infections, including tick-borne fever and human granulocytic anaplasmosis are also disclosed.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Greene, Jr., George R.
Sepetka, Ivan
Lei, Cathy
Nguyen, Rupal
Bradley, Matthew J.
Ahlers, Stephen T.
Goforth, Carl W.
Stone, James R.
Abrégé
A temporary aortic occlusion device is disclosed, having an expandable locator portion and an expandable occlusion portion. The expandable locator portion assists a user in determining whether the distal end of the device has been advanced within a patient's aorta, and the occlusion portion is expanded to occlude the patient's aorta, preferably below the renal arteries.
A61B 17/12 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets pour ligaturer ou comprimer par un autre moyen les parties tubulaires du corps, p.ex. les vaisseaux sanguins ou le cordon ombilical
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig
Pepe, Frank
Brindza, Michael
Abrégé
The invention comprises synergistic compositions of at least one metal polycarboxylate and lithium phosphate. The synergistic compositions are designed to be added to film-forming or other compositions to reduce the corrosion of various metal surfaces or substrates on which the synergistic compositions are applied.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig
Walles, Joshua
Thompson, Kaitlyn
Abrégé
Composition and process for preparing corrosion-resistant passive coatings on bulk-aluminum alloys and aluminum powder-pigments; said coatings derived from an acidic aqueous composition consisting essentially of potassium hexafluorozirconate, basic chromium sulfate and potassium tetrafluoroborate.
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Nelson, Daniel, C.
Etobayeva, Irina, V.
Abrégé
The present invention relates to methods of treating or preventing a bacterial disease or infection, antibacterial compositions, and antibacterial surfaces, including an isolated polypeptide comprising an enzymatically active domain (EAD) of a Bacillus bacteriophage endolysin.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF DEFENSE (USA)
Inventeur(s)
Liacouras, Peter
Yang, Michael
Abrégé
The subject matter of the instant invention relates to a dental implant surgical apparatus and system comprising a customized dental ridge augmentation matrix and one or, optionally, a plurality of dental implant surgical drill guides, and methods of use thereof.
A61B 17/17 - Dispositifs de guidage pour les forets
A61C 3/04 - Supports pour tenir les instruments à forer les dents dans l'ordre de leur emploi
A61C 8/00 - Moyens destinés à être fixés à l'os de la mâchoire pour consolider les dents naturelles ou pour y assujettir des prothèses dentaires; Implants dentaires; Outils pour l'implantation
A61C 13/00 - Prothèses dentaires; Leurs procédés de fabrication
A61C 13/12 - Outils pour la fixation des dents artificielles; Supports, crochets ou montures pour dents artificielles
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Hall, Aaron, A.
Cronin, William, A.
Mahon, Richard, T.
Johnson, William, R.
Abrégé
A method for the prevention of the onset of pulmonary oxygen toxicity and/or reduction of decrements of pulmonary function due to pulmonary oxygen toxicity comprising administration of a prophylactically effective amount of an anticholinergic, optionally together with a pharmaceutically acceptable excipient.
A61P 11/00 - Médicaments pour le traitement des troubles du système respiratoire
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61K 31/38 - Composés hétérocycliques ayant le soufre comme hétéro-atome d'un cycle
A61K 31/395 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines
A61K 31/46 - Aza-8-bicyclo[3.2.1]octane; Ses dérivés, p.ex. atropine, cocaïne
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig
Grieve, Alan
Abrégé
The aluminum anode alloy consists essentially of an aluminum base and effective amounts of tin and indium. The aluminum alloy is useful as a sacrificial metallic coating, as a protective aluminum anode, and as a pigment in polymeric coatings.
B32B 15/01 - Produits stratifiés composés essentiellement de métal toutes les couches étant composées exclusivement de métal
B32B 15/20 - Produits stratifiés composés essentiellement de métal comportant de l'aluminium ou du cuivre
B32B 27/20 - Produits stratifiés composés essentiellement de résine synthétique caractérisée par l'emploi d'additifs particuliers utilisant des charges, des pigments, des agents thixotropiques
C09D 5/10 - Peintures anti-corrosion contenant une poudre métallique
THE UNITED STATE OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Regeimbal, James, M.
Tyner, Stuart, D.
Abrégé
The subject matter of the instant invention relates to methods of enhancing harvesting of phages against a targeted host bacteria, as well as methods of identifying phages likely to have an enhanced propensity to infect and kill an infectious pathogenic bacteria in vivo, from samples comprising phages. The invention also relates to phage libraries, pharmaceutical compositions, methods of treatment, and phage-based diagnostic methods and methods of detecting bacteria related thereto.
THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Phillips, Jonathan
Abrégé
A capacitor having first and second electrodes and a scaffold dielectric. The scaffold dielectric comprises an insulating material with a plurality of longitudinal channels extending across the dielectric and filled with a liquid comprising cations and anions. The plurality of longitudinal channels are substantially parallel and the liquid within the longitudinal channels generally has an ionic strength of at least 0.1. Capacitance results from the migrations of positive and negative ions in the confined liquid in response to an applied electric field. A method of supplying power to a load using the capacitor and a method of making the capacitor is additionally disclosed.
H01G 11/62 - Condensateurs hybrides, c. à d. ayant des électrodes positive et négative différentes; Condensateurs électriques à double couche [EDL]; Procédés de fabrication desdits condensateurs ou de leurs composants Électrolytes Électrolytes liquides caractérisés par le soluté, p.ex. sels, anions ou cations
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Biswas, Biswajit
Malagon Bautista, Francisco, Jesus
Estrella, Luis, Angel
Abrégé
Methods of detecting actively growing host organisms, including bacterial organisms, involving the detection of ribonucleic acid (RNA) products produced by unmodified infectious bioagenis that infect the host organisms are provided. Related methods of assessing drug susceptibility and resistance are further provided. In addition to these surrogate detection methods, related reaction mixtures, kits, systems, and microfluidic cards are also provided.
C12Q 1/04 - Détermination de la présence ou du type de micro-organisme; Emploi de milieux sélectifs pour tester des antibiotiques ou des bactéricides; Compositions à cet effet contenant un indicateur chimique
C12Q 1/6888 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour la détection ou l’identification d’organismes
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Cochran, Grant, K.
Abrégé
A radiograph stand allowing weight placed on an injured leg/foot be measured and recorded while taking a weight-bearing radiograph, A method for taking weight bearing radiograph of a patient's foot, ankle, leg. knee, thigh, hip, pelvis, and spine.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig
Pepe, Frank
Brindza, Michael
Walles, Joshua
Abrégé
The invention comprises synergistic compositions of at least two metal carboxylates as corrosion inhibitors based on polycarboxylate anions and a variety of different cations. The inhibitors are designed to be added to film forming or other compositions to reduce the corrosion of the metal substrate on which the synergistic compositions are applied.
THE UNITED STATES OF AMERICA AS REPRSENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Millenbaugh, Nancy
Gleaton, Jeremy Wesley
Kirul, Dickson Klprono
Abrégé
The invention relates to methods of treating a fungal infection in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a composition comprising one or more antifungal peptides selected from the group consisting of BmKn2, dBmKn2, Kn2-7, and dKn2-7. Antifungal pharmaceutical compositions and dosage forms, including field-deployable dosage forms, comprising one or more of these antifungal peptides are also contemplated herein.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
TEALL, Charlotte (Royaume‑Uni)
Inventeur(s)
Venn-Watson, Stephanie Kay
Baird, Mark
Abrégé
Compositions including a fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods for treatment and prophylaxis of conditions related to anemic conditions, are provided, including compositions and methods for treating anemic conditions such as hemolytic anemia and anemia of chronic disease, and other related conditions.
A61K 31/20 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique
A61K 31/202 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique ayant au moins trois doubles liaisons, p.ex. acide linolénique
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
TEALL, Charlotte (Royaume‑Uni)
Inventeur(s)
Venn-Watson, Stephanie Kay
Abrégé
Compositions including an fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods for treatment and prophylaxis of conditions related to inflammation and conditions related to inflammation, including anemia of chronic disease, insulin resistance, metabolic syndrome, autoimmune disease, hypertension, diabetes, nonalcoholic fatty liver disease, cardiovascular disease, cancer, aging, neurodegenerative diseases, including Alzheimer's disease and other forms of dementia, and other related conditions, and other related conditions.
A61K 31/20 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p.ex. composés antiphlogistiques et pour le cœur
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p.ex. agents antirhumatismaux; Médicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p.ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p.ex. antidiabétiques
A61P 5/50 - Médicaments pour le traitement des troubles du système endocrinien des hormones pancréatiques pour augmenter ou potentialiser l'activité de l'insuline
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Biswas, Biswajit
Henry, Matthew, S.
Regeimbal, James, M.
Abrégé
The subject matter of the instant invention relates to methods of compounding compositions comprising bacteriophage effective for treating bacterial infections, including but not limited to, multidrug resistant bacterial infections. The invention also relates to compositions, bacterial diversity sets, and phage libraries prepared according to the methods of the instant invention.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Bertrand, Jacques, C.
Abrégé
The invention relates to compositions comprising one or more insecticides and further comprising a carrier composition comprising one or more glycols, and methods of controlling an insect population comprising applying said compositions to the insect habitat using a thermal fogger.
A01N 25/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'application; Substances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles
29.
HARNESSING QUANTUM DOTS TO STUDY, VISUALIZE, AND PROMOTE IMMUNE TOLERANCE
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Jewell, Christopher, M.
Hess, Krystina
Medintz, Igor
Susumu, Kimihiro
Oh, Eunkeu
Abrégé
Provided are compositions and methods for promoting tolerance to auto-immune antigens. In general the compositions include quantum dots (QDs) that are in association with auto-immune peptide antigens. It is shown that QDs can be used to generate immunological tolerance by controlling the density of self-antigen on QDs. Peptide-QDs rapidly concentrate in draining lymph nodes, and co-localize with macrophages expressing scavenger receptors involved in tolerance. Treatment with peptide-QDs reduces disease incidence 10-fold. The degree of tolerance and the underlying expansion of regulatory T cells correlates with the density of myelin molecules presented on QDs such that higher numbers of tolerogenic particles displaying lower levels of self-peptide are more effective for inducing tolerance than fewer particles each displaying higher densities of peptide. The disclosure is therefore relevant to promoting tolerance to antigens that are involved in a variety of autoimmune disorders.
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p.ex. par les adjuvants chimiques
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Arafat, Ei Sayad
Abrégé
This invention relates to non aqueous non-volatile alkylated siloxane compositions having low VOC and vapor pressure of about 31 millimeters of mercury at 20°C. consisting essentially of a mixture of a linear or open-chain methyl alkylated siloxane having two silicon atoms and a siloxane having three silicon atoms alkylated with methyl groups.
THE UNITED STATES OF AMERICA as representd by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Bertrand, Jacques, C.
Abrégé
The invention relates to methods of trapping a pest, said method comprising providing ferromagnetic particles for ingestion by the pest, and trapping the pest using one or more magnets, wherein a trapped pest has ingested and internally accumulated an amount of the ferromagnetic particles sufficient to permit immobilization of the pest using said one or more magnets. Devices for use with the methods of the instant invention are also disclosed.
A01N 25/08 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'application; Substances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des solides comme supports ou diluants
A01N 59/00 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, contenant des éléments ou des composés inorganiques
32.
PROCESS OF PROTECTING METAL SUBSTRATES WITH CORROSION-RESISTANT COMPOSITIONS
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig, A.
Nickerson, William
Abrégé
This invention relates to galvanic aluminum alloy powder-pigments coated with semi-conducting corrosion-inhibiting compositions and particularly to the process for preparing said coated powder-pigments for coating substrates to inhibit corrosion. The coated aluminum alloy powder-pigments are electrically active and prevent corrosion of metals which are more cathodic (electropositive) than the coated-aluminum alloy pigments.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig, A.
Nickerson, William
Abrégé
This invention relates to sacrificial-metal pigments coated with an effective amount of at least one metal oxide or a combination of metal oxides such as a mixture of chromium and zirconium oxides, and the process for preparing said coated pigments and combination thereof with film-forming binders for coating metal substrates to inhibit corrosion. The coated sacrificial-metal pigments are electrically active to prevent corrosion of metal substrates that are more cathodic (electropositive) than the metal oxide coated metal pigments.
B01J 29/06 - Zéolites aluminosilicates cristallines; Leurs composés isomorphes
B01J 37/02 - Imprégnation, revêtement ou précipitation
C03C 17/10 - Traitement de surface du verre, p.ex. du verre dévitrifié, autre que sous forme de fibres ou de filaments, par revêtement par des métaux par dépôt à partir d'une phase liquide
34.
SYNTHETIC ANTIGEN CONSTRUCTS AGAINST CAMPYLOBACTER JEJUNI
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry, Patricia
Jiao, Yuening
Monteiro, Mario, Artur
Pequegnat, Brittany, Michele
Abrégé
The invention relates to immunogenic synthetic constructs capable of inducing an immune response against Campylobacter jejuni (C. jejuni) in a subject comprising one or more monosaccharides comprising one or more MeOPN moieties. Specifically, the invention relates to immunogenic synthetic constructs capable of inducing an immune response against C. jejuni in a subject comprising one or more MeOPN-6-Gal monosaccharides, one or more MeQPN-4-Gal monosaccharides, and/or one or more MeOPN-2-Gal monosaccharides. The invention also relates to compositions comprising the immunogenic synthetic constructs, and methods of inducing an immune response against C. jejuni in a subject comprising administering the immunogenic synthetic constructs, and/or compositions comprising the immunogenic synthetic constructs, to the subject. Methods of treating, preventing, or ameliorating a C. jejuni bacterial infection in a subject comprising administering to the subject one or more doses of immunoglobulins directed to one or more of the MeOPN moieties are also contemplated.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Simmons, Monika
Putnak, Joseph, R.
Abrégé
The invention relates to a method for preventing, ameliorating or treating disease caused by dengue vims in a subject in need thereof comprising administering to the subject a dengue vaccine formulation in combination with a NS3 helicase polypeptide and/or fragment(s) thereof, wherein said method comprises stimulating humoral as well as cell- mediated immunity to the dengue virus in the subject,
C07K 1/00 - Procédés généraux de préparation de peptides
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p.ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Kellar, Kevin
Abrégé
Methods and systems for determining true time delay from each receiving element of an 'active electronically scanned array' (AESA) or a phased array antenna. Embodiments of the invention can include electromagnetic EM elements, optical waveguides, and wavelength selective FGBs are collectively configured as a plurality of dual purpose elements that couples an EM field and uses an induced voltage to change an index of refraction of the optical waveguide's electro-optic (EO) material, where the EO material will also function as a dielectric in an antenna element, where the signals comprising optical signals propagate through EM element acting as phase delay elements, where the measuring system compares the reflected signals with a reference signal with no phase delay to determine said signals phase delay.
G01S 7/03 - DÉTERMINATION DE LA DIRECTION PAR RADIO; RADIO-NAVIGATION; DÉTERMINATION DE LA DISTANCE OU DE LA VITESSE EN UTILISANT DES ONDES RADIO; LOCALISATION OU DÉTECTION DE LA PRÉSENCE EN UTILISANT LA RÉFLEXION OU LA RERADIATION D'ONDES RADIO; DISPOSITIONS ANALOGUES UTILISANT D'AUTRES ONDES - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe - Détails de sous-ensembles HF spécialement adaptés à ceux-ci, p.ex. communs à l'émetteur et au récepteur
G01S 13/42 - Mesure simultanée de la distance et d'autres coordonnées
H01Q 3/00 - Dispositifs pour changer ou faire varier l'orientation ou la forme du diagramme de directivité des ondes rayonnées par une antenne ou un système d'antenne
37.
INSECT CONTROL FORMULATION WITH IMPROVED AUTODISSEMINATION CHARACTERISTICS
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Bertrand, Jacques, C.
Abrégé
An insecticide composition designed for improved autodissemination. The insecticide may be used as a dry powder or a wet composition. The composition allows for better transfer of active ingredient to the target species, as well as improved stability of the active ingredient.
A01N 25/08 - Biocides, produits repoussant ou attirant les animaux nuisibles, ou régulateurs de croissance des végétaux, caractérisés par leurs formes, ingrédients inactifs ou modes d'application; Substances réduisant les effets nocifs des ingrédients actifs vis-à-vis d'organismes autres que les animaux nuisibles contenant des solides comme supports ou diluants
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Galameau, Michael
Mitchell, Ray
Brock, Johnny
Wing, Vern
Blood, Christopher, G.
Zouris, James
Walker, Jay
Nix, Ralph
Elkins, Trevor
Negus, Tracy
D'Souza, Edwin
Abrégé
The present invention is a software, methods, and system for creating and editing a medical logistics simulation model and for presenting the simulation model simulated within a military or disaster relief scenario. A user interface that allows a user to enter and edit platforms and associated attributes for a simulation model. The system runs the simulation model based on user input and historical data stored in databases using the inventive software. The present invention provides an output for allowing a user to view casualty rates, patient streams, and medical requirements or any other desired aspect of the simulation model.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G06F 17/40 - Acquisition et consignation de données
G06F 19/00 - Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des applications spécifiques (spécialement adaptés à des fonctions spécifiques G06F 17/00;systèmes ou méthodes de traitement de données spécialement adaptés à des fins administratives, commerciales, financières, de gestion, de surveillance ou de prévision G06Q;informatique médicale G16H)
G06Q 50/24 - Gestion de dossiers médicaux (traitement de données médicales ou biologiques à des fins scientifiques G06F 19/00)
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY FO THE NAVY (USA)
Inventeur(s)
Arafat, Ei, Sayad
Abrégé
An oleaginous corrosion-resistant lubricating composition comprising at least one alpha-olefin synthetic oil and effective amounts of metal salts of sulfonic acids/carboxylic acids, alkylated aromatic compounds as solubility modifiers, pour-point depressants, at least one antioxidant, and metal deactivators.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry, Patricia
Jiao, Yuening
Monteiro, Mario, Artur
Abrégé
The invention relates to immunogenic synthetic constructs capable of inducing an immune response against Campylobacter jejuni (C. jejuni) in a subject comprising one or more monosaccharides comprising one or more MeOPN moieties. Specifically, the invention relates to immunogenic synthetic constructs capable of inducing an immune response against Campylobacter jejuni (C, jejuni) in a subject comprising one or more MeOPN⃗6 Gal monosaccharides. The invention also relates to compositions comprising the immunogenic synthetic constructs and methods of inducing an immune response against C. jejuni in a subject comprising administering the immunogenic synthetic constructs, and/or compositions comprising the immunogenic synthetic construct, to the subject.
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Calvo, David, C.
Thangawng, Abel, L.
Abrégé
An apparatus in a surrounding liquid and methods of using same. The apparatus includes an acoustic Fresnel zone plate comprising a compliant frame, a substrate connected to the frame, and an acoustic diffraction grating connected to the substrate. The acoustic diffraction grating includes a plurality of concentric rings or a plurality of concentric islands. The substrate is acoustic - impedance-mismatched with the acoustic diffraction grating. The acoustic Fresnel zone plate includes at least one acoustic focal spot. The substrate is acoustic-impedance-mismatched with the surrounding liquid and the acoustic diffraction grating is acoustic-impedance-matched with the surrounding liquid, or the substrate is acoustic-impedance-matched with the surrounding liquid and the acoustic diffraction grating is acoustic-impedanee-mismatehed with the surrounding liquid.
THE UNITED STATES OF AMERICA AS REPRESENTED BY TH SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry, Patricia
Savarino, Stephen
Monteiro, Mario, Artur
Abrégé
The inventive subject matter relates to a construct comprising antigens derived from multiple enterobacteria including Campylobacter jejuni capsule polysaccharide polymer, enterotoxigenic Escherichia coli recombinant polypeptide construct and lipopolysaecharide from Shigella spp.. The subject invention also relates to a method of inducing an immune response utilizing the inventive composition.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Dory, Roy, Edward
Alvarez, Rene
Burdette, Alexander, Justin
Abrégé
This invention is directed to a portable lightweight, easy-carry, reusable, and self-contained assembly for sterilizing contaminated equipment using ozone and humidity generated in situ without requiring external electricity, fuels or other exogenous energy sources for operation and a method of use thereof.
A61L 2/20 - Procédés ou appareils de désinfection ou de stérilisation de matériaux ou d'objets autres que les denrées alimentaires ou les lentilles de contact; Accessoires à cet effet utilisant des substances chimiques des substances gazeuses, p.ex. des vapeurs
44.
IMMUNOGENIC COMPOSITION AGAINST CAMPYLOBACTER JEJUNI
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry, Patricia
Monteiro, Mario, Artur
Abrégé
The inventive subject matter relates to an immunogenic composition against Campylobacter jejuni comprising isolated capsule polysaccharide from selected pathogenic Campylobacter jejuni strains. The inventive subject matter also relates to methods of using the polysaccharide compositions in inducing and anti-C. jejuni immune response.
THE UNITED STATES OF AMERICA as representated by THE SECRETARY OF THE NAVY (USA)
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF DEFENSE (USA)
Inventeur(s)
Gordon, Chad
Armand, Mehran
Murphy, Ryan
Grant, Gerald
Liacouras, Peter
Wolfe, Kevin
Abrégé
A surgical system is provided. The system includes a reference unit, an implant and a detector. The reference unit includes a first trackable element. The implant includes a second trackable element. The detector is configured to provide at least one signal corresponding to a detected location of at least one of the first trackable element and the second trackable element.
A61B 17/56 - Instruments ou procédés chirurgicaux pour le traitement des os ou des articulations; Dispositifs spécialement adaptés à cet effet
A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Murphy, Ryan
Basafa, Ehsan
Armand, Mehran
Gordon, Chad
Grant, Gerald
Abrégé
Disclosed is a method of simulating mastication. The method includes obtaining computer-readable three-dimensional representations of a first skeletal fragment including a portion of at least one of a mandible and a maxilla and of a recipient skeletal fragment including a portion of at least one of a mandible and a maxilla. The method also includes obtaining placement data and obtaining muscle insertion data. The method also includes simulating a contraction of a muscle positioned according to the muscle insertion data in a representation of a surgical hybrid comprising at least a portion of the first skeletal fragment positioned according to the placement data relative to at least a portion of the recipient skeletal fragment. The method also includes outputting a representation of mastication represented by the simulating.
A61B 17/56 - Instruments ou procédés chirurgicaux pour le traitement des os ou des articulations; Dispositifs spécialement adaptés à cet effet
A61B 19/00 - Instruments, outillage ou accessoires pour la chirurgie ou le diagnostic non couverts par l'un des groupes A61B 1/00-A61B 18/00, p.ex. pour stéréotaxie, opération aseptique, traitement de la luxation, protecteurs des bords des blessures(masques de protection du visage A41D 13/11; blouses de chirurgien ou vêtements pour malades A41D 13/12; dispositifs pour retirer, traiter ou transporter les liquides du corps A61M 1/00)
A61C 7/00 - Orthodontie, c. à d. obtention ou maintien de la position désirée des dents, p.ex. par redressage, nivellement, ajustement, séparation, ou par correction des malocclusions
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF DEFENSE (USA)
Inventeur(s)
Gordon, Chad
Armand, Mehran
Murphy, Ryan
Grant, Gerald
Liacouras, Peter
Wolfe, Kevin
Basafa, Ehsan
Abrégé
A method for computer-assisted planning of a transplant surgery is provided. The method includes obtaining a computer-readable representation of a donor and recipient skeletal fragment; determining surgical cutting planes on the computer-readable representation of the donor skeletal fragment from which a portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment will be harvested; determining virtual cutting guides; performing a virtual osteotomy to separate the portion of the donor skeletal fragment from the computer-readable representation of the donor skeletal fragment from a remainder portion of the donor skeletal fragment based on a position of the virtual cutting guides that are attached to the computer-readable representation of the donor skeletal fragment; positioning the donor skeletal fragment within a transplant region of the recipient skeletal fragment; and creating a hybrid computer-readable representation comprising the recipient skeletal fragment and the portion of the donor skeletal.
A61B 17/56 - Instruments ou procédés chirurgicaux pour le traitement des os ou des articulations; Dispositifs spécialement adaptés à cet effet
A61B 17/16 - Ostéoclastes; Forets ou ciseaux pour os; Trépans
A61F 2/00 - Filtres implantables dans les vaisseaux sanguins; Prothèses, c.-à-d. éléments de substitution ou de remplacement pour des parties du corps; Appareils pour les assujettir au corps; Dispositifs maintenant le passage ou évitant l'affaissement de structures corporelles tubulaires, p.ex. stents
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Chesi, Simone
Romano, Marcello
Abrégé
A method of simulating 3 -degrees of freedom spacecraft rotational dynamics is provided that includes attaching a payload, using a spherical air bearing, to an inner gimbal of a 3- axis gimbal, where the 3 -axis gimbal includes an outer gimbal, a mid-gimbal and the inner gimbal, using a motion controller to control motion of each the gimbal of the 3 -axis gimbal, where the motion controller includes an appropriately programmed computer and a motion control motor, sensing limits of free travel of the spherical air bearing, using a position sensor, and changing a position of the 3 -axis gimbal away from the limit of free travel of the spherical air bearing when the spherical air bearing approaches the limit of free travel, wherein the position change effects travel of the spherical bearing to be unbounded by the limit of free travel, wherein 4π steradians spacecraft dynamics of the payload are simulated.
G09B 9/12 - Systèmes de déplacement pour simulateurs d'aéronef
G09B 9/52 - Simulateurs pour l'enseignement ou l'entraînement pour l'enseignement de la conduite des véhicules ou autres moyens de transport pour enseigner le pilotage d'un véhicule spatial
A63G 31/16 - Installations pour divertissements publics créant l'illusion d'un voyage
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Pope, Martin
Briere, Thomas, A.
Moore, Robert, P.
Przybylska, Nina
Muja, Oliviu
Abrégé
A splice kit is provided for repairing a cable (12) having a central conductor (22), an insulator (24) surrounding the central conductor, an outer conductive sheath (26) surrounding the insulator, and a jacket (28) surrounding the outer conductive sheath. The splice kit includes a central conductor joint (46) that is electrically conductive and is configured to engage the central conductor of the cable such that the central conductor joint defines a portion of an electrical path of the central conductor. The splice kit also includes a dielectric insert (48) configured to at least partially surround the central conductive joint and the central conductor of the cable, and an outer sheath joint (52) that is electrically conductive and is configured to at least partially surround the dielectric insert. The outer sheath joint is configured to be electrically connected to the outer conductive sheath of the cable such that the outer sheath joint defines a portion of an electrical path of the outer conductive sheath. The splice kit further includes a jacket joint (54) configured to at least partially surround the outer sheath joint and the jacket of the cable.
H02G 1/16 - Méthodes ou appareils spécialement adaptés à l'installation, entretien, réparation, ou démontage des câbles ou lignes électriques pour réparer l'isolant ou l'armature des câbles
H02G 15/18 - Jonctions de câbles protégées par des manchons, p.ex. pour câble de télécommunication
H01R 9/05 - Dispositifs de connexion conçus pour assurer le contact avec plusieurs des conducteurs d'un câble multiconducteur pour câbles coaxiaux
H02G 1/14 - Méthodes ou appareils spécialement adaptés à l'installation, entretien, réparation, ou démontage des câbles ou lignes électriques pour la jonction ou la terminaison de câbles
50.
MULTIPLEX AMPLIFICATION REACTION METHOD FOR DETERMINATION OF CAMPYLOBACTER JEJUNI PENNER/CAPSULE TYPE
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (USA)
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (USA)
Inventeur(s)
Poly, Frederic
Guerry, Patricia
Parker, Craig
Abrégé
The inventive method and associated reagents relate to a molecular approach to determining Campylobacter jejuni capsule/Penner types. The invention also relates to a method of identifying Campylobacter jejuni types using primers in a multiplex PCR assay.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p.ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
51.
INERTIAL SENSOR USING SLIDING PLANE PROXIMITY SWITCHES
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Swanson, Paul, D.
Waters, Richard, L.
Tally, Charles
Wang, Andrew
Abrégé
A time-domain inertial sensor comprising: a support structure having an electrode plane parallel to an x-y plane of an x-y-z mutually orthogonal coordinate system, wherein the support structure's largest dimension lies within the x-y plane; a proof mass having a first surface parallel to the x-y plane; wherein the proof mass is springedly coupled to the support structure such that the first surface is separated from the electrode plane by a gap; a driver configured to drive the proof mass to oscillate with respect to the support structure in approximately only the x-direction such that, while oscillating, the gap does not vary significantly; and a first, time-domain, proximity switch disposed to switch from an open state to a closed state each time the proof mass is in a first reference position with respect to the support structure.
G01C 19/56 - Dispositifs sensibles à la rotation utilisant des masses vibrantes, p.ex. capteurs vibratoires de vitesse angulaire basés sur les forces de Coriolis
52.
HIGH THERMAL CONDUCTIVITY MATERIALS FOR THERMAL MANAGEMENT APPLICATIONS
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Broido, David A.
Reinecke, Tom L.
Lindsay, Lucas R.
Abrégé
High thermal conductivity materials and methods of their use for thermal management applications are provided. In some embodiments, a device comprises a heat generating unit (304) and a thermally conductive unit (306, 308, 310) in thermal communication with the heat generating unit (304) for conducting heat generated by the heat generating unit (304) away from the heat generating unit (304), the thermally conductive unit (306, 308, 310) comprising a thermally conductive compound, alloy or composite thereof. The thermally conductive compound may include Boron Arsenide, Boron Antimonide, Germanium Carbide and Beryllium Selenide.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Savarino, Stephen
Abrégé
The inventive subject matter relates to a recombinant polypeptide construct comprising enterotoxigenic Escherichia coli fimbrial subunits. The recombinant polypeptide constructs comprise multiple subunits to the same or different ETEC fimbrial types. The constructs are useful for inclusion in immunogenic formulations for the inductin of immunity against entertoxigenic Escherichia coli. The inventive subject matter also relates to the use of the recombinant polypeptide constructs in induce anti- enterotoxigenic Escherichia coli.
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig, A.
Nickerson, William
Abrégé
This invention relates to galvanic aluminum alloy powder-pigments coated with semi-conducting corrosion inhibiting compositions and to the process for preparing said coated powder-pigments for coating metal substrates to inhibit corrosion. The coated aluminum alloy powder-pigments are electrically active and prevent corrosion of metals which are more cathodic (electropositive) than the coated aluminum alloy pigments.
B05D 7/24 - Procédés, autres que le flocage, spécialement adaptés pour appliquer des liquides ou d'autres matériaux fluides, à des surfaces particulières, ou pour appliquer des liquides ou d'autres matériaux fluides particuliers pour appliquer des liquides ou d'autres matériaux fluides particuliers
B32B 15/02 - Produits stratifiés composés essentiellement de métal autrement que sous forme de feuille, p.ex. en fils, en parcelles
C23C 22/00 - Traitement chimique de surface de matériaux métalliques par réaction de la surface avec un milieu réactif laissant des produits de réaction du matériau de la surface dans le revêtement, p.ex. revêtement par conversion, passivation des métaux
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Waters, Richard, L.
Swanson, Paul, D.
Abrégé
A gyroscope comprising: a frame; a tuning fork comprising a base and first and second prongs, wherein the base has proximal and distal ends, and wherein the proximal end is coupled to the frame and the distal end is coupled to the first and second prongs; first and second drivers configured to drive the first and second prongs respectively to oscillate with respect to the frame in a first direction, such that the prongs oscillate at their respective resonant frequencies and 1800 out of phase with each other; and at least two digital position triggers operatively coupled to the frame and to the tuning fork, wherein each position trigger is configured to experience at least two trigger events during each oscillation of the tuning fork in a second direction, wherein the second direction is orthogonal to the first direction.
G01C 19/5607 - Dispositifs sensibles à la rotation utilisant des masses vibrantes, p.ex. capteurs vibratoires de vitesse angulaire basés sur les forces de Coriolis utilisant des diapasons vibrants
56.
OXIDE COATED METAL PIGMENTS AND FILM-FORMING COMPOSITIONS
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig, A.
Nickerson, William
Abrégé
Sacrificial-metal pigments are coated with an effective amount of at least one metal oxide or a combination of metal oxides such as a chromium-zirconium oxide, and the process for preparing said coated pigments and combination thereof with film-forming binders for coating metal substrates to inhibit corrosion. The coated sacrificial-metal pigments are electrically active to prevent corrosion of metal substrates that are more.
C09D 5/00 - Compositions de revêtement, p.ex. peintures, vernis ou vernis-laques, caractérisées par leur nature physique ou par les effets produits; Apprêts en pâte
C09K 13/06 - Compositions pour l'attaque chimique, la gravure, le brillantage de surface ou le décapage contenant un acide inorganique avec une substance organique
C23C 28/02 - Revêtements uniquement de matériaux métalliques
H01B 1/02 - Conducteurs ou corps conducteurs caractérisés par les matériaux conducteurs utilisés; Emploi de matériaux spécifiés comme conducteurs composés principalement de métaux ou d'alliages
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Deckard, Aaron
Dick, Glen
Denesha, Paul
Holzmeyer, Michael
Buechler, James
Abrégé
A weapon mounting system for a vehicle, such as a helicopter. The weapon mounting system illustratively includes a weapon cradle supporting a machine gun for pivoting movement about a generally horizontal elevational axis. A carriage supports the weapon cradle and is supported by a pintle for rotation about a generally vertical azimuth axis. An ejection collection device is supported by the carriage and collects spent shell casings and links ejected from the machine gun for discharge through the pintle. A trigger assembly illustratively provides for manual operation by a gunner and for remote electrical operation by a pilot.
F41A 9/55 - Moyens de guidage fixes montés sur, ou près, de la chambre de cartouche
B64D 7/06 - Agencement à bord aéronefs des équipements militaires, p.ex. des armes, des accessoires d'armement ou des blindages de protection; Adaptations des installations d'armement aux aéronefs les armes étant des armes à feu mobiles
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Swanson, Paul, D.
Waters, Richard, L.
Abrégé
An inertial device is disclosed. In one embodiment, the device comprises a support structure and first and second spring mass systems coupled to the support structure. The first spring mass system comprises first and second time domain digital triggers configured to measure rotation and displacement respectively of the support structure about a first axis and along an orthogonal second axis. The second spring mass system comprises third and fourth time domain digital triggers configured to measure acceleration and displacement respectively of the support structure about the second axis and along the first axis.
G01C 19/5762 - Dispositifs sensibles à la rotation utilisant des masses vibrantes, p.ex. capteurs vibratoires de vitesse angulaire basés sur les forces de Coriolis utilisant des masses planaires vibrantes entraînées dans une vibration de translation le long d’un axe - Details de structure ou topologie les dispositifs ayant une seule masse de détection la masse de détection étant reliée à une masse d'entraînement, p.ex. cadres d'entraînement
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Swanson, Paul, D.
Waters, Richard, L.
Abrégé
A gyroscope comprising: a support structure: a drive mass springedly coupled to the support structure such that movement of the drive mass with respect to the support structure is substantially restricted to movement in a first direction; a driver configured to cause the drive mass to oscillate with respect to the support structure in the first direction; a sense mass springedty coupled to the drive mass such that movement of the sense mass with respect to the drive mass is substantially restricted to movement in a second direction, which is orthogonal to the first direction; and a digital trigger comprising a proximity switch coupled between the drive mass and the sense mass, wherein the switch is configured to switch from an open state to a closed state each time the sense mass is in a reference position with respect to the drive mass.
G01C 19/5762 - Dispositifs sensibles à la rotation utilisant des masses vibrantes, p.ex. capteurs vibratoires de vitesse angulaire basés sur les forces de Coriolis utilisant des masses planaires vibrantes entraînées dans une vibration de translation le long d’un axe - Details de structure ou topologie les dispositifs ayant une seule masse de détection la masse de détection étant reliée à une masse d'entraînement, p.ex. cadres d'entraînement
60.
TEMPO-MEDIATED GLYCOCONJUGATION OF AN IMMUNOGENIC COMPOSITION AGAINST CAMPYLOBACTER JEJUNI
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry, Patricia
Monteiro, Mario, Artur
Abrégé
Provided are methods of producing an immunogenic capsule polysaccharide polymer composition with improved structural integrity and immunogenic properties, and it's use to elicit an immune response to Campylobacter jejuni.
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Waters, Richard
Swanson, Paul, D.
Abrégé
Apparatus and methods for a resonator with reduced acceleration sensitivity and phase noise using a time domain switch. In one embodiment, the resonator comprises: a frame; a first oscillator configured to oscillate with respect to the frame; a first driver configured to drive the first oscillator at the first oscillator's resonant frequency; a first half of a first relative position switch mounted to the first oscillator; a second oscillator having substantially the same resonant frequency as the first oscillator, wherein the first and second oscillators are designed to respond in substantially the same manner to external perturbations to the frame; a second half of the first relative position switch mounted to the second oscillator; and wherein as the first oscillator oscillates there is relative motion between the first and second oscillators such that the first relative position switch passes through a closed state in each oscillation when the first and second switch halves pass by each other.
H03B 5/30 - Production d'oscillation au moyen d'un amplificateur comportant un circuit de réaction entre sa sortie et son entrée l'élément déterminant la fréquence étant un résonateur électromécanique
62.
ALUMINUM ALLOY COATED PIGMENTS AND CORROSION-RESISTANT COATINGS
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig, A.
Nickerson, William
Abrégé
This Invention relates to galvanic aluminum alloy powder-figments coated with a semi-conducting corrosion inhibiting oxide ad the process for preparing said coated powder-pigments in combination with film-forming binders for coating metal substrates to inhibit corrosion. The coated aluminium alloy powder-pigments are electrically active aid prevent corrosion of metals which are more catholic (electropositive) than the aluminium alloy pigments;
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Bennett, William
Abrégé
A cushioning bandage with absorbent properties, configured to permit easy positioning over a wound. The bandage comprises a highly lofted lamb's wool pad attached to variable lengths of elastic material. The bandage is configured for easy application to patients.
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Swanson, Paul, D.
Waters, Richard, L.
Abrégé
An oscillatory apparatus and methods of utilizing the same. In one embodiment, the apparatus comprises a force sensor having a proof mass, with one or more sensing electron tunneling electrodes disposed thereon, and a frame comprising one or more reference electron tunneling electrodes. Conductive plates disposed on the sensor base and capping wafers induce oscillations of the proof mass. The sensing and the reference electrode pairs are disposed in a face-to-face configuration, thus forming a digital switch characterized by one or more closed states. In the closed state, the switch generates triggering events, thereby enabling the sensing apparatus to generate a digital output indicative of the mass position. The time period between consecutive trigger events is used to obtain mass deflection due to external forcing. Time separation between the triggering events is based on the physical dimensions established during fabrication, thus not requiring ongoing sensor calibration.
THE UNITED STATE OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Dos Santos, Frank
Nguyen, Chi
Abrégé
A device for automatic monitoring intravenous fluid flow rate and temperature. The inventive device is capable of automatically adjusting the temperature of the fluid administered to a patient and recording the fluid flow rate and temperature. The device is also capable of transferring data to an electronic data storage repository via a wire connection or wirelessly.
THE UNITED STATES OF AMERICA AS REPRESENTRD BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Desilva, Mauris, N.
Tiba, Amer
O'Connor, Karen, H.
Giles, Patty-Fu
Abrégé
A method provides immediate, direct and controlled time release of an effective amount of therapeutics to a wound site for a prolonged period. The pharmaceutical formulation comprising a plurality of nanoparticles, said nanoparticles encapsulating a therapeutically effective amount of one or more antibacterial agents, and an application of the formulation to an implant before surgery provide for extended release of said antibacterial agents.
B01J 13/00 - Chimie des colloïdes, p.ex. production de substances colloïdales ou de leurs solutions, non prévue ailleurs; Fabrication de microcapsules ou de microbilles
67.
CAPSULE COMPOSITION FOR USE AS IMMUNOGEN AGAINST CAMPYLOBACTER JEJUNI
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry, Patricia
Monteiro, Mario, Artur
Abrégé
Immunogenic compositions, and method of using the compositions to elicit an immune response against Campylobacter jejuni. The compositions are isolated polysaccharide polymers derived from Camplylobacter jejuni capsule.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Lu, Shin-Tsu
Abrégé
A method and device to temporarily incapacitate a subject for a prolonged period by first applying to said subject a continuous pulsed electric waveform to incapacitate the subject, followed by applying a second intermittent pulsed electric waveform to the subject, which safely maintains the incapacitation of the subject with forced breathing.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Felgner, Phillip, L.
Trieu, Angela
Doolan, Denise
Abrégé
The invention relates to antigens, associated with sterile immunity, and methods of their use, in an immunogenic formulation to confer an immune response against Plasmodium falciparum. The inventive antigens were identified by their association with sterile immunity against malaria.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Ching, Wei-Mei
Chao, Chien-Chung
Chen, Hua-Wei
Abrégé
A method for detection blood borne pathogen in whole blood, comprising collecting a blood sample from a subject, heating said sample for a period of time, adding said heated sample to a pre-mixed LAMP solution comprising one or more LAMP primer set, and Bst DNA polymerase to create a reaction mixture, incubating said reaction mixture for a period of time and determining the presence of blood born pathogen.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
THE UNITED STATES OF AMERICA, represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Arafat, El Sayed
Abrégé
This invention relates to non-volatile siloxane compositions having low VOC, a flash point above 140°F, and a vapor pressure of less than seven millimeters of mercury (7mm Hg). The non-volatile siloxane compositions consist essentially of specific amounts of alkylated cyclosiloxane have 5 or 6 repeating siloxane units, an alkylated cyclosiloxane having 3 or 4 repeating siloxane units, at least one alkylene glycol alkyl ether acetate and monohydric aliphatic alcohols.
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Casares, Sofia, A.
Richie, Thomas, L.
Brumeanu, Teodor
Abrégé
Provided is a transgenic animal model for testing immunogenicity and protective efficacy of human vaccines and the method for generating such a multitransgenic animal. Also disclosed are methods for screening compositions for human vaccine development. More specifically, a mouse model capable of expressing human leukocyte antigen DR4, and human costimulatory molecules (CD80) upon infusion of human HLA-matched hematopoietic stem cells, which can develop into a functional human immune system is provided.
C12N 15/00 - Techniques de mutation ou génie génétique; ADN ou ARN concernant le génie génétique, vecteurs, p.ex. plasmides, ou leur isolement, leur préparation ou leur purification; Utilisation d'hôtes pour ceux-ci
73.
RT-LAMP ASSAY FOR THE DETECTION OF PAN-SEROTYPE DENGUE VIRUS
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Dauner, Allison
Pal, Subhamoy
Wu, Shuenn-Jue
Abrégé
The disclosure relates to a reverse transcription loop-mediated isothermal amplification (LAMP) assay for the detection of dengue virus. The assay is capable of simultaneous detection of 1-4 serotypes of dengue virus in a single reaction. The disclosure also provides a set of primers including degenerate primers for the assay. The sequence regions of serotypes 1-4 for primer design are also illustrated.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
C07H 21/04 - Composés contenant au moins deux unités mononucléotide comportant chacune des groupes phosphate ou polyphosphate distincts liés aux radicaux saccharide des groupes nucléoside, p.ex. acides nucléiques avec le désoxyribosyle comme radical saccharide
74.
MULTIPLEX AMPLIFICATION REACTION METHOD FOR DETERMINATION OF CAMPYLOBACTER JEJUNI PENNER/CAPSULE TYPE
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (USA)
GOVERNMENT OF THE UNITED STATES as represented by THE SECRETARY OF THE ARMY (USA)
Inventeur(s)
Poly, Frédéric
Guerry, Patricia
Mason, Carl
Serichantalergs, Oralak
Abrégé
The inventive method and associated reagents relate to a molecular approach to determining Campylobacter jejuni capsule/Penner types. The invention also relates to a method of identifying Campylobacter jejuni types using the inventive primers in a multiplex PCR assay.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Arafat, El, Sayed
Abrégé
The present invention relates to non-volatile organic compositions having a VOC of about zero, a flash point above 14O0F, and a vapor pressure of less than seven millimeters of mercury (7mm Hg). The non- volatile organic compositions comprise an alkylated cyclicsiloxane having 5 to 8 repeating siloxane units, an alkylated cyclicsiloxane having 3 or 4 repeating siloxane units, and at least one glycol alkyl ether.
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Casares, Sofia, A.
Richie, Thomas, L.
Brumeanu, Teodor, D.
Abrégé
The present invention relates to recombinant chimeric molecules that are capable of providing T cell receptor (TCR) interaction and costimulation for activation and differentiation of pathogen-specific T cells toward effector T helper 1 (Th I) or T helper 2 (Th2) cells. The chimera may capable of elicit antibodies against pathogen-specific B cell epitope(s). The present invention also relates method of using these chimeric molecules in whole or as a component of a vaccine.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Sedegah, Martha
Richie, Thomas
Abrégé
The invention relates immunogenic polypeptides and epitopes from Plasmodium falciparum protein AMAl. The epitopes contain HLA class I binding motifs and stimulate an anti-malaria CD8+ T-cell response. The polypeptides can be incorporated into immunogenic formulations against malaria. Additionally, the antigens are useful for facilitating evaluation of immunogenicity of candidate malaria vaccines.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Limbach, Keith
Aguiar, Joao
Sedegah, Martha
Richie, Thomas
Abrégé
The invention provides novel malaria polypeptides expressed at the preerythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Tran, Thanh, Nhon
Abrégé
A thermoelectric generator has a hot side heat exchanger comprising: a silicon carbide (SiC) honeycomb support with a plurality of passages. The passage walls are coated with a pyrophoric solid fuel such as red oxide (Fe2O3) in combination with a silicon (Si) binder. A quantum well thermoelectric device is positioned between the hot side heat exchanger and heat sink. The performance of the thermoelectric generator is comparable to fuel cells. The thermoelectric generator is small and portable.
H01L 35/30 - DISPOSITIFS À SEMI-CONDUCTEURS; DISPOSITIFS ÉLECTRIQUES À L'ÉTAT SOLIDE NON PRÉVUS AILLEURS - Détails fonctionnant exclusivement par effet Peltier ou effet Seebeck caractérisés par les moyens d'échange de chaleur à la jonction
80.
METHOD FOR MAKING A TRANSDUCER, TRANSDUCER MADE THEREFROM, AND APPLICATIONS THEREOF
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Parpia, Jeevak M.
Craighead, Harold G.
Cross, Joshua D.
Ilic, Bojan Robert
Zalalutdinov, Maxim K.
Baldwin, Jeffrey W.
Houston, Brian H.
Abrégé
A method for manufacturing or preparing thin-film stacks that exhibit moderate, finite, stress-dependent resistance and which can be incorporated into a transduction mechanism that enables simple, effective signal to be read out from a micro- or nano-mechanical structure. As the structure is driven, the resistance of the intermediate layers is modulated in tandem with the motion, and with suitable dc-bias, the motion is directly converted into detectable voltage. In general, detecting signal from MEMS or NEMS devices is difficult, especially using a method that is able to be integrated with standard electronics. The thin-film manufacturing or preparation technique described herein is therefore a technical advance in the field of MEMS/NEMS that could enable new applications as well as the ability to easily develop CMOS-MEMS integrated fabrication techniques. Also disclosed are: (i) transducers where current flows across a piezo layer from one major surface to the opposite major surface; and (ii) methods of making a transducer the resistivity of a piezoresistive layer is decreased and/or the gauge factor of a piezoresistive layer is increased.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Parpia, Jeevak M.
Craighead, Harold G.
Cross, Joshua D.
Ilic, Bojan Robert
Zalalutdinov, Maxim K.
Baldwin, Jeffrey W.
Houston, Brian H.
Abrégé
The present invention is directed to a CMOS integrated micromechanical device fabricated in accordance with a standard CMOS foundry fabrication process. The standard CMOS foundry fabrication process is characterized by a predetermined layer map and a predetermined set of fabrication rules. The device includes a semiconductor substrate formed or provided in accordance with the predetermined layer map and the predetermined set of fabrication rules. A MEMS resonator device is fabricated in accordance with the predetermined layer map and the predetermined set of fabrication rules. The MEMS resonator device includes a micromechanical resonator structure having a surface area greater than or equal to approximately 20 square microns. At least one CMOS circuit is coupled to the MEMS resonator member. The at least one CMOS circuit is also fabricated in accordance with the predetermined layer map and the predetermined set of fabrication rules.
H03H 3/007 - Appareils ou procédés spécialement adaptés à la fabrication de réseaux d'impédance, de circuits résonnants, de résonateurs pour la fabrication de résonateurs ou de réseaux électromécaniques
H03H 9/02 - Réseaux comprenant des éléments électromécaniques ou électro-acoustiques; Résonateurs électromécaniques - Détails
H03H 3/00 - Appareils ou procédés spécialement adaptés à la fabrication de réseaux d'impédance, de circuits résonnants, de résonateurs
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Shortridge, Robert, G.
Yamamoto, Christina, M.
Abrégé
PerchIorate-free green flare compositions are disclosed which, when burned, produce green smoke and flames. Methods of producing the compositions are also disclosed.
C06C 15/00 - Compositions pyrophoriques; Pierres à briquet
C06B 33/04 - Compositions contenant des particules de métal, alliage, bore, silicium, sélénium ou tellure avec au moins un matériau fournissant de l'oxygène, qui est soit un oxyde métallique, soit un sel, organique ou inorganique, susceptible de donner un oxyde m le matériau étant un sel inorganique d'un composé d'azote et d'oxygène
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Yamamoto, Christina, M.
Shortridge, Robert, G.
Abrégé
Perchlorate-free flare compositions are disclosed which, when burned, produce yellow smoke and flames. Methods of producing the compositions are also disclosed.
C06C 15/00 - Compositions pyrophoriques; Pierres à briquet
C06B 33/14 - Compositions contenant des particules de métal, alliage, bore, silicium, sélénium ou tellure avec au moins un matériau fournissant de l'oxygène, qui est soit un oxyde métallique, soit un sel, organique ou inorganique, susceptible de donner un oxyde m le matériau étant formé de plusieurs composés donneurs d'oxygène un composé au moins étant un sel inorganique d'un composé d'azote et d'oxygène
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Shortridge, Robert, G.
Yamamoto, Christina, M.
Abrégé
Perchlorate-free flare compositions are disclosed which, when burned, produce red smoke and flames. Methods of producing the compositions are also disclosed.
C06C 15/00 - Compositions pyrophoriques; Pierres à briquet
C06B 33/04 - Compositions contenant des particules de métal, alliage, bore, silicium, sélénium ou tellure avec au moins un matériau fournissant de l'oxygène, qui est soit un oxyde métallique, soit un sel, organique ou inorganique, susceptible de donner un oxyde m le matériau étant un sel inorganique d'un composé d'azote et d'oxygène
85.
RECOMBINANT ANTIGENS FOR DIANGNOSIS AND PREVENTION OF SPOTTED FEVER RICKETTSIAE
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Ching, Wei-Mei
Abrégé
The invention relates to the construction of recombinant, immunodominant polypeptides against spotted fever group Rickettsia. The invention also relates to a method for the use of the recombinant proteins, either singly or in combination, in detection and diagnostic assays of spotted fever. The proteins can also be used to induce immune response against spotted fever group Rickettsia.
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Wei-Mei, Ching
Chien-Chung, Chao
Abrégé
Recombinant chimeric antigens comprising unmodified and modified reactive polypeptide fragments of expressed product of the recombinant 56 kDa proteins of multiple strain of scrub typhus, such as Karp, Kato (Ktr56), Gilliam (Gmr56), and TA763 (TAr56). The invention is useful for detecting prior exposure to a number of strains of scrub typhus, based on the strength of reaction toward the chimeric protein and as a component in vaccine formulations and production of immune globulins for passive prophylaxis and immunity in subjects against heterologous infections.
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Doolan, Denise
Abrégé
A vaccine comprising an immunogenic preparation containing a Plasmodium antigen or a fragment thereof, wherein said antigen is selected from a group consisting of PyAg2, PfAg2, PvAg2, PkAg2, PoAg2, PmAg2, PbAg2, PcAg2 and a combination thereof. A vaccination method comprising administering a priming immunization preparation containing a Plasmodium antigen or fragment thereof, wherein said antigen is selected from a group consisting of PyAg2, PfAg2, PvAg2, PkAg2, PoAg2, PmAg2, PbAg2, PcAg2 and a combination thereof, and administrating a boosting immunization preparation containing said Plasmodium antigen or fragment, wherein said antigen is selected from a group consisting of PyAg2, PfAg2, PvAg2, PkAg2, PoAg2, PmAg2, PbAg2, PcAg2 and a combination thereof.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
GENERAL DYNAMICS INFORMATION TECHNOLOGY (USA)
Inventeur(s)
Ragain, James, C.
Charlton, David
Tiba, Amer
Abrégé
This invention describes an adhesive used for bonding dental and medical biomaterials to hard tissues via a molecular bridge formed from calcium-reactive amines and acrylic or methacrylic ester monomers to hard tissues such as enamel, dentin, and bone. This formulation consists of an acid-stable polymerizable compound with multi-functional acrylate cross-linkers. This formula provides good self-adherence without prior preparation of the hard tissue substrates. The formulation can contain chemical- and/or light-activated free-radical initiators.
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (USA)
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Read, Timothy
Sozhamannan, Shanmuga
Abrégé
This invention encompasses for an isolated Bacillus phage AP50 that has one or more nucleotide substitutions in the phage genome, whereby the one or more nucleotide substitutions increase lytic activity of the phage. In addition, the invention encompasses for proteins expressed by the phages, compositions containing the proteins and/or the phage as well as methods of using the Bacillus phage AP50 to test for the presence of B. anthracis.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry-Kopecko, Patricia
Monteiro, Mario, Artur
Abrégé
An immunogenic composition, and method of using the composition to elicit an immune response to Campylobacter jejuni. The composition is an isolated polysaccharide polymer composed of one or more forms of disaccharide polymers.
D06P 1/00 - Procédés généraux de teinture ou d'impression des textiles ou procédés généraux de teinture du cuir, des fourrures ou des substances macromoléculaires solides de toutes formes, classés selon les teintures, les pigments ou les substances auxiliaires u
92.
INDUCTION OF AN IMMUNE RESPONSE AGAINST DENGUE VIRUS USING PRIME-BOOST APPROACH
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Simmons, Monika
Porter, Kevin, R.
Wellington, Sun
Kanakatte, Raviprkash
Abrégé
The invention relates to methods for the induction of an immune response to dengue virus. The method of inducing an immune response against dengue virus comprising administration of a non-replicating immunogen followed by a boost with a tetravalent live attenuated viral vaccine. Another aspect of the inventive subject matter is a method of inducing an immune response against dengue virus using a heterologous prime-boost regimen with the priming immunogen comprising a DNA expression system, an adenovirus expression vector or a Venezuelan equine encephalitis virus replicon system and the boosting immunogen comprising the same without the DNA expression system. Each expression system contains DNA sequences encoding dengue viral proteins.
A61K 31/715 - Polysaccharides, c. à d. ayant plus de cinq radicaux saccharide liés les uns aux autres par des liaisons glycosidiques; Leurs dérivés, p.ex. éthers, esters
93.
SECRETED CAMPYLOBACTER FLAGELLA COREGULATED PROTEINS AS IMMUNOGENS
THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry-Kopecko, Patricia
Baqar, Shahida
Abrégé
The invention relates to an immunogenic composition composed of secreted polypeptides derived from Campylobacter jejuni non-flagellar proteins that are coordinately expressed with the flagellar regulon. The invention also relates to a method of inducing an immune response to the non-flagellar protein polypeptides.
THE UNITED STATES OF AMERICA, as represented by the SECRETARY OF THE NAVY (USA)
Inventeur(s)
Wun-Fogle, Marilyn
Abrégé
A magnetostrictive alloy containing iron and gallium comprising: Fe100 - (x + y + z)GaxA1yCz; where x is of from about 5 at. % to about 30 at. %; where x + y is of from about 5 at. % to about 30 at. %; and where z is of from about 0.005 at. % to about 4.1 at. %. The alloys can also contain B and N.
H01F 1/00 - Aimants ou corps magnétiques, caractérisés par les matériaux magnétiques appropriés; Emploi de matériaux spécifiés pour leurs propriétés magnétiques
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Freilich, Daniel, A.
Abrégé
A pharmaceutical formulation capable of supplying replacement blood volume and tissue oxygenation as well as other functions, such as procoagulation and pharmacological interventions, in order to enhance survivability in patients with severe blood loss. The invention also discloses a formulation and method of using the - formulation in bridging severe blood loss using a multifunctional blood substitute in a prehospital setting.
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Ching, Wei-Mei
Abrégé
The invention relates to the construction of recombinant, immunodominant Rickettsia typhi proteins. The invention also relates to a method for the use of the recombinant proteins, either singly or in combination, in detection and diagnostic assays. The proteins can also be used in anti-Rickettsia typhi immunogenic formulations.
THE UNITED STATES OF AMERICA AS RESPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Savarino, Stephen, J.
Holmes, Randall, K.
Jobling, Michael, G.
Abrégé
The inventive subject matter relates to an immunogenic composition composed of a chimeric molecule including a conformationally stable adhesin from Escherichia coli fused to a bacterial toxin A subunit, such as cholera toxin A subunit or heat-labile Escherichia coli toxin A subunit. The invention also relates to the adhesin-toxin chimera noncovalently associated with a toxin B subunit of the same or different species as the A subunit. The invention also relates to a method of utilizing an adhesin/toxin fusion composition to elicit an immune response.
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Savarino, Stephen, J.
Holmes, Randall, K.
Jobling, Michael, G.
Abrégé
The inventive subject matter relates to an immunogenic composition composed of a chimeric molecule including a conformationally stable adhesin from Escherichia coli fused to a bacterial toxin A subunit, such as cholera toxin A subunit or heat-labile Escherichia coli toxin A subunit. The invention also relates to the adhesin-toxin chimera noncovalently associated with a toxin B subunit of the same or different species as the A subunit. The invention also relates to a method of utilizing an adhesin/toxin fusion composition to elicit an immune response.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Cullum, Malford, E.
Duplessis, Christopher, A.
Crepeau, Loring, J.
Abrégé
The inventive subject matter relates to a competitive method measuring stress biomarkers in bodily fluids including serum, urine and oral fluids including saliva. The inventive method measures biomarkers including Cortisol, melatonin and secretory IgA by fluorescence polarization fluorescence lifetime analysis or fluorescence resonance energy transfer.
G01N 33/53 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet
G01N 33/543 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
100.
COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE