THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig
Grieve, Alan
Abrégé
The aluminum anode alloy consists essentially of an aluminum base and effective amounts of tin and indium. The aluminum alloy is useful as a sacrificial metallic coating, as a protective aluminum anode, and as a pigment in polymeric coatings.
C23C 30/00 - Revêtement avec des matériaux métalliques, caractérisé uniquement par la composition du matériau métallique, c. à d. non caractérisé par le procédé de revêtement
3.
COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF ANEMIA
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Venn-Watson, Stephanie Kay
Baird, Mark
Abrégé
Compositions including a fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods for treatment and prophylaxis of conditions related to anemic conditions, are provided, including compositions and methods for treating anemic conditions such as hemolytic anemia and anemia of chronic disease, and other related conditions.
A61K 31/20 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique
A61K 31/202 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique ayant au moins trois doubles liaisons, p.ex. acide linolénique
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Venn-Watson, Stephanie Kay
Abrégé
Compositions including an fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods for treatment and prophylaxis of conditions related to inflammation and conditions related to inflammation, including anemia of chronic disease, insulin resistance, metabolic syndrome, autoimmune disease, hypertension, diabetes, nonalcoholic fatty liver disease, cardiovascular disease, cancer, aging, neurodegenerative diseases, including Alzheimer's disease and other forms of dementia, and other related conditions, and other related conditions.
A61K 31/20 - Acides carboxyliques, p.ex. acide valproïque ayant un groupe carboxyle lié à une chaîne acyclique d'au moins sept atomes de carbone, p.ex. acides stéarique, palmitique ou arachidique
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p.ex. composés antiphlogistiques et pour le cœur
A61P 1/16 - Médicaments pour le traitement des troubles du tractus alimentaire ou de l'appareil digestif des troubles de la vésicule biliaire ou du foie, p.ex. protecteurs hépatiques, cholagogues, cholélitholytiques
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p.ex. antidiabétiques
A61P 5/50 - Médicaments pour le traitement des troubles du système endocrinien des hormones pancréatiques pour augmenter ou potentialiser l'activité de l'insuline
A61P 9/00 - Médicaments pour le traitement des troubles du système cardiovasculaire
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p.ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p.ex. agents antirhumatismaux; Médicaments anti-inflammatoires non stéroïdiens [AINS]
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Biswas, Biswajit
Henry, Matthew S.
Regeimbal, James M.
Abrégé
The subject matter of the instant invention relates to methods of compounding compositions comprising bacteriophage effective for treating bacterial infections, including but not limited to, multidrug resistant bacterial infections. The invention also relates to compositions, bacterial diversity sets, and phage libraries prepared according to the methods of the instant invention.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Sinfield, Matthew
Farren, Jeffrey
Wong, Richard
Martin, William J.
Smith, Richard H.
Para, Shane
Heilmann, James E.
Novotny, Paul M.
Ray, Patrick C.
Deantonio, Dan
Stravinskas, Joe
Abrégé
An exemplary welding consumable according to the invention is provided and includes up to about 0.13 wt % carbon, about 0.3 wt % to about 1.4 wt % manganese, about 7.25 wt% to about 11.5 wt % nickel, about 0.6 wt % to about 1.2 wt % molybdenum, about 0.2 wt % to about 0.7 wt % silicon, up to about 0.3 wt % vanadium, up to about 0.05 wt % titanium, up to about 0.08 wt % zirconium, up to about 2.0 wt % chromium, and a balance of iron and incidental impurities.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry, Patricia
Savarino, Stephen
Monteiro, Mario Artur
Abrégé
The inventive subject matter relates to a construct comprising antigens derived from multiple enterobacteria including Campylobacter jejuni capsule polysaccharide polymer, enterotoxigenic Escherichia coli recombinant polypeptide construct and lipopolysaecharide from Shigella spp.. The subject invention also relates to a method of inducing an immune response utilizing the inventive composition.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Guerry, Patricia
Monteiro, Mario Artur
Abrégé
The inventive subject matter relates to an immunogenic composition against Campylobacter jejuni comprising isolated capsule polysaccharide from selected pathogenic Campylobacter jejuni strains. The inventive subject matter also relates to methods of using the polysaccharide compositions in inducing and anti-C. jejuni immune response.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Savarino, Stephen
Abrégé
The inventive subject matter relates to a recombinant polypeptide construct comprising enterotoxigenic Escherichia coli fimbrial subunits. The recombinant polypeptide constructs comprise multiple subunits to the same or different ETEC fimbrial types. The constructs are useful for inclusion in immunogenic formulations for the inductin of immunity against entertoxigenic Escherichia coli. The inventive subject matter also relates to the use of the recombinant polypeptide constructs in induce anti- enterotoxigenic Escherichia coli.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig A.
Nickerson, William
Abrégé
Sacrificial-metal pigments are coated with an effective amount of at least one metal oxide or a combination of metal oxides such as a chromium-zirconium oxide, and the process for preparing said coated pigments and combination thereof with film-forming binders for coating metal substrates to inhibit corrosion. The coated sacrificial-metal pigments are electrically active to prevent corrosion of metal substrates that are more.
C23C 22/06 - Traitement chimique de surface de matériaux métalliques par réaction de la surface avec un milieu réactif laissant des produits de réaction du matériau de la surface dans le revêtement, p.ex. revêtement par conversion, passivation des métaux au moyen de solutions aqueuses au moyen de solutions aqueuses acides d'un pH < 6
C23F 11/10 - Inhibition de la corrosion de matériaux métalliques par application d'inhibiteurs sur la surface menacée par la corrosion ou par addition d'inhibiteurs à l'agent corrosif dans d'autres liquides au moyen d'inhibiteurs organiques
11.
ALUMINUM ALLOY COATED PIGMENTS AND CORROSION-RESISTANT COATINGS
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig A.
Nickerson, William
Abrégé
This Invention relates to galvanic aluminum alloy powder-figments coated with a semi-conducting corrosion inhibiting oxide ad the process for preparing said coated powder-pigments in combination with film-forming binders for coating metal substrates to inhibit corrosion. The coated aluminium alloy powder-pigments are electrically active aid prevent corrosion of metals which are more catholic (electropositive) than the aluminium alloy pigments;
C09D 5/10 - Peintures anti-corrosion contenant une poudre métallique
C23C 22/00 - Traitement chimique de surface de matériaux métalliques par réaction de la surface avec un milieu réactif laissant des produits de réaction du matériau de la surface dans le revêtement, p.ex. revêtement par conversion, passivation des métaux
C23F 11/00 - Inhibition de la corrosion de matériaux métalliques par application d'inhibiteurs sur la surface menacée par la corrosion ou par addition d'inhibiteurs à l'agent corrosif
12.
PLASMODIUM FALCIPARUM SPOROZOITE AND LIVER STAGE ANTIGENS
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Limbach, Keith
Aguiar, Joao
Sedegah, Martha
Richie, Thomas
Abrégé
The invention provides novel malaria polypeptides expressed at the preerythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Limbach, Keith
Aguiar, Joao
Sedegah, Martha
Richie, Thomas
Abrégé
The invention provides novel malaria polypeptides expressed at the pre- erythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
UNIVERSITY OF GUELPH (Canada)
Inventeur(s)
Guerry-Kopecko, Patricia
Monteiro, Mario Artur
Abrégé
An immunogenic composition, and method of using the composition to elicit an immune response to Campylobacter jejuni. The composition is an isolated polysaccharide polymer composed of one or more forms of disaccharide polymers.
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Matzdorf, Craig A.
Nickerson, William C., Jr.
Abrégé
This invention comprises an acidic aqueous solution for treating metal substrates to improve the adhesion bonding and corrosion protection of the metal surface which comprises effective amounts of water soluble trivalent chromium compounds, fluorozirconates, effective amounts of at least one corrosion inhibitors such as benzotriazole, fluorometallic compounds, zinc compounds, thickeners, surfactants, and at least about 0.001 mole per liter of the acidic solution of a polyhydroxy and/or carboxylic compound as a stabilizing agent for the aqueous solution.
C23C 22/34 - Traitement chimique de surface de matériaux métalliques par réaction de la surface avec un milieu réactif laissant des produits de réaction du matériau de la surface dans le revêtement, p.ex. revêtement par conversion, passivation des métaux au moyen de solutions aqueuses au moyen de solutions aqueuses acides d'un pH < 6 contenant des fluorures ou des fluorures complexes
C23C 22/50 - Traitement du fer ou des alliages à base de fer
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (USA)
Inventeur(s)
Savarino, Stephen J.
Abrégé
The inventive subject matter relates to the methods for the induction of immunity and prevention of diarrhea resulting from Escherichia coli. The inventive subject matter also relates to the use Escherichia coli adhesins as immunogens and to the construction of conformationally stability and protease resistant Escherichia coli adhesin constructs useful for inducing immunity to Escherichia coli pathogenic bacteria. The methods provide for the induction of B-cell mediated immunity and for the induction of antibody capable of inhibiting the adherence and colonization of Escherichia.coli, including. enterotoxigenic Escherichia coli, to human cells.
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