09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable molecular diagnostic medical
software for electronic testing and detection of DNA and RNA
by electrical signals, for preventing, detecting and
reporting existence of viral, bacterial, or fungal pathogen
types; recorded or downloadable molecular diagnostic medical
software for contaminant testing in the fields of
agriculture, food and beverage, environment, and animal
health; recorded or downloadable molecular diagnostic
software for testing of pathogens in the fields of
agriculture, food and beverage, environment, and animal
health. Providing medical and scientific research information via
the internet; research and development of new products for
medical diagnostic monitoring and testing; platform as a
service for electronic testing and detection of DNA and RNA
by electrical signals, for preventing, detecting and
reporting existence of viral, bacterial, or fungal pathogen
types; research and development in the field of agriculture,
biochemistry, microbiology and microorganisms; platform as a
services featuring software for the identification of
pathogens; environmental testing.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable molecular diagnostic medical software for electronic testing and detection of DNA and RNA by electrical signals, for preventing, detecting and reporting existence of viral, bacterial, or fungal pathogen types; Recorded or downloadable molecular diagnostic medical software for contaminant testing in the fields of agriculture, food and beverage, environment, and animal health; Recorded or downloadable molecular diagnostic software for testing of pathogens in the fields of agriculture, food and beverage, environment, and animal health Providing medical and scientific research information via the internet; Research and development of new products for medical diagnostic monitoring and testing; Platform as a service for electronic testing and detection of DNA and RNA by electrical signals, for preventing, detecting and reporting existence of viral, bacterial, or fungal pathogen types; Research and development in the field of agriculture, biochemistry, microbiology and microorganisms; Platform as a services featuring software for the identification of pathogens; Environmental testing
Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
G01N 33/487 - Physical analysis of biological material of liquid biological material
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care.
A vial adaptor is disclosed. The vial adaptor can include a cap member and a piston. The cap member can removably couple to a vial storing, for example, liquid constituent for facilitating sample collection for detecting pathogens. The piston can distally translate through the cap member and into the vial to generate volume displacement and positive pressure, which can cause the liquid constituent stored in the vial to flow out from the vial via a channel formed within the piston. The piston can include a cover that creates a water-tight seal with an inner surface of the vial.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable molecular diagnostic medical software for electronic testing and detection of DNA and RNA by electrical signals for diagnosing and reporting the existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders An electronic molecular diagnostic medical apparatus for electronically detecting and testing DNA and RNA by electrical signals for preventing, detecting and reporting existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders Providing medical and scientific research information via the internet; research and development of new products for medical diagnostic monitoring
10.
SYSTEMS AND METHODS OF SAMPLE DEPOSITING AND TESTING
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers, for example, using loop-mediated isothermal amplification (LAMP). Some implementations include additional improvements, such as improvements to sample and reagent mixing, sample deposition, and compensation of inhibitors in the sample. Also disclosed herein are nucleic acid primers for use in the sensitive and specific detection of pathogens in biological samples by LAMP, which may be performed in the devices disclosed herein. The biological samples may be derived from patients including humans, plants, food, soil, contaminated surfaces, or animals such as livestock.
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care. In some implementations, the systems and methods herein implement a reader device, an assay cartridge, and a mobile or external device configured to receive abiological sample, test the biological sample, and provide test results to a patient or user associated with the patient. The test results may be packaged with additional information, including symptoms suffered by the patient, a diagnosis, and follow-up instructions. In some embodiments, the test results may also be provided with or aggregated with other test results to generate aggregate information.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
G01N 27/14 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of an electrically-heated body in dependence upon change of temperature
12.
ISOTHERMAL AMPLIFICATION WITH ELECTRICAL DETECTION
Some embodiments of the methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include performing a recombinase polymerase amplification (RPA) and, optionally, a second isothermal amplification reaction. In some embodiments, the second isothermal amplification reaction includes loop-mediated isothermal amplification (LAMP). In some embodiments, the second isothermal amplification reaction is performed in conjunction with the RPA. In some embodiments, the second isothermal amplification reaction is performed on amplification products of the RPA. Some embodiments also include detecting the presence of amplification products by measuring a modulation of an electoral signal such as impedance.
Embodiments relate to methods, systems and compositions for reducing nonspecific amplification in isothermal amplification reactions. Some embodiments relate to reducing nonspecific amplification in loop-mediated isothermal amplification (LAMP) reactions with certain oligonucleotides.
C12Q 1/6848 - Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
The present application is generally directed to systems, methods, and devices for diagnostics for identifying whether patients, locations, or items are infected or contaminated with a pathogen and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers, for example, using loop-mediated isothermal amplification (LAMP) analysis of biological samples. In some implementations, a remote device may be integrated to enable third parties to identify whether people are infected and to review wellness scores for the people. The biological samples may be derived from patients including humans, plants, food, soil, contaminated surfaces, or animals such as livestock.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers, for example, using loop-mediated isothermal amplification (LAMP). In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Also disclosed herein are nucleic acid primers for use in the sensitive and specific detection of pathogens in biological samples by LAMP, which may be performed in the devices disclosed herein. The biological samples may be derived from patients including humans, plants, food, soil, contaminated surfaces, or animals such as livestock.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers, for example, using loop-mediated isothermal amplification (LAMP). In some implementations, additional improves, such as improvements to sample and reagent mixing, sample deposition, and compensation of inhibitors in the sample. Also disclosed herein are nucleic acid primers for use in the sensitive and specific detection of pathogens in biological samples by LAMP, which may be performed in the devices disclosed herein. The biological samples may be derived from patients including humans, plants, food, soil, contaminated surfaces, or animals such as livestock.
G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
17.
METHODS AND COMPOSITIONS FOR DETECTION OF AMPLIFICATION PRODUCTS
Some embodiments of the systems, devices, kits and methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include a droplet comprising an aqueous reaction mixture and an oil, and a detection unit. Some embodiments include a passageway or conduit configured to transport the droplet. In some embodiments, the detection unit includes an electric field-generating unit and an electro-sensing element.
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers, for example, using loop-mediated isothermal amplification (LAMP). In some implementations, additional improves, such as improvements to sample and reagent mixing, sample deposition, and compensation of inhibitors in the sample. Also disclosed herein are nucleic acid primers for use in the sensitive and specific detection of pathogens in biological samples by LAMP, which may be performed in the devices disclosed herein. The biological samples may be derived from patients including humans, plants, food, soil, contaminated surfaces, or animals such as livestock.
G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
19.
IMPROVEMENT IN LAMP AMPLIFICATION IN A DIAGNOSTIC DEVICE
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers, for example, using loop-mediated isothermal amplification (LAMP). In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Also disclosed herein are nucleic acid primers for use in the sensitive and specific detection of pathogens in biological samples by LAMP, which may be performed in the devices disclosed herein. The biological samples may be derived from patients including humans, plants, food, soil, contaminated surfaces, or animals such as livestock.
Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
G01N 33/487 - Physical analysis of biological material of liquid biological material
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable medical software for testing and
detection of DNA and RNA; recorded or downloadable medical
software for diagnosing and reporting the existence or
symptoms of disease in the nature of endocrine disorders,
metabolic disorders including obesity, oncologic disorders,
renal disorders, urologic disorders, hepatic disorders,
disorders of the nervous system, infectious disorders,
immunologic disorders, gastrointestinal disorders,
respiratory and pulmonary disorders, cardiovascular
disorders, hematologic disorders, reproductive disorders,
ocular disorders, dermatologic disorders, psychological
disorders, and musculoskeletal disorders. A medical diagnostic apparatus for detecting and testing DNA
and RNA; medical diagnostic apparatus for preventing,
detecting and reporting existence or symptoms of disease in
the nature of endocrine disorders, metabolic disorders
including obesity, oncologic disorders, renal disorders,
urologic disorders, hepatic disorders, disorders of the
nervous system, infectious disorders, immunologic disorders,
gastrointestinal disorders, respiratory and pulmonary
disorders, cardiovascular disorders, hematologic disorders,
reproductive disorders, ocular disorders, dermatologic
disorders, psychological disorders, and musculoskeletal
disorders. Providing medical and scientific research information via
the internet; research and development of new products.
24.
ISOTHERMAL AMPLIFICATION WITH ELECTRICAL DETECTION
Some embodiments of the methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include performing a recombinase polymerase amplification (RPA) and, optionally, a second isothermal amplification reaction. In some embodiments, the second isothermal amplification reaction includes loop-mediated isothermal amplification (LAMP). In some embodiments, the second isothermal amplification reaction is performed in conjunction with the RPA. In some embodiments, the second isothermal amplification reaction is performed on amplification products of the RPA. Some embodiments also include detecting the presence of amplification products by measuring a modulation of an electoral signal such as impedance.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
G01N 27/04 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
G01N 27/414 - Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
25.
METHODS AND COMPOSITIONS FOR DETECTION OF AMPLIFICATION PRODUCTS
Some embodiments of the systems, devices, kits and methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include a droplet comprising an aqueous reaction mixture and an oil, and a detection unit. Some embodiments include a passageway or conduit configured to transport the droplet. In some embodiments, the detection unit includes an electric field-generating unit and an electro-sensing element.
Embodiments relate to methods, systems and compositions for reducing nonspecific amplification in isothermal amplification reactions. Some embodiments relate to reducing nonspecific amplification in loop-mediated isothermal amplification (LAMP) reactions with certain oligonucleotides.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides
27.
HANDHELD IMPEDANCE-BASED DIAGNOSTIC TEST SYSTEM FOR DETECTING ANALYTES
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care. In some implementations, the systems and methods herein implement a reader device, an assay cartridge, and a mobile or external device configured to receive a biological sample, test the biological sample, and provide test results to a patient or user associated with the patient. The test results may be packaged with additional information, including symptoms suffered by the patient, a diagnosis, and follow-up instructions. In some embodiments, the test results may also be provided with or aggregated with other test results to generate aggregate information.
G01N 27/00 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
G01N 1/38 - Diluting, dispersing or mixing samples
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
G01N 27/22 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
G01N 37/00 - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES - Details not covered by any other group of this subclass
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
28.
ISOTHERMAL AMPLIFICATION WITH ELECTRICAL DETECTION
Some embodiments of the methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include performing a recombinase polymerase amplification (RPA) and, optionally, a second isothermal amplification reaction. In some embodiments, the second isothermal amplification reaction includes loop-mediated isothermal amplification (LAMP). In some embodiments, the second isothermal amplification reaction is performed in conjunction with the RPA. In some embodiments, the second isothermal amplification reaction is performed on amplification products of the RPA. Some embodiments also include detecting the presence of amplification products by measuring a modulation of an electoral signal such as impedance.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
G01N 27/04 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
G01N 27/414 - Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides
29.
HANDHELD IMPEDANCE-BASED DIAGNOSTIC TEST SYSTEM FOR DETECTING ANALYTES
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care. In some implementations, the systems and methods herein implement a reader device, an assay cartridge, and a mobile or external device configured to receive a biological sample, test the biological sample, and provide test results to a patient or user associated with the patient. The test results may be packaged with additional information, including symptoms suffered by the patient, a diagnosis, and follow-up instructions. In some embodiments, the test results may also be provided with or aggregated with other test results to generate aggregate information.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
30.
METHODS AND COMPOSITIONS FOR DETECTION OF AMPLIFICATION PRODUCTS
Some embodiments of the systems, devices, kits and methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include a droplet comprising an aqueous reaction mixture and an oil, and a detection unit. Some embodiments include a passageway or conduit configured to transport the droplet. In some embodiments, the detection unit includes an electric field-generating unit and an electro-sensing element.
Embodiments relate to methods, systems and compositions for reducing nonspecific amplification in isothermal amplification reactions. Some embodiments relate to reducing nonspecific amplification in loop-mediated isothermal amplification (LAMP) reactions with certain oligonucleotides.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable medical software for testing and
detection of DNA and RNA; recorded or downloadable medical
software for diagnosing and reporting the existence or
symptoms of disease in the nature of endocrine disorders,
metabolic disorders including obesity, oncologic disorders,
renal disorders, urologic disorders, hepatic disorders,
disorders of the nervous system, infectious disorders,
immunologic disorders, gastrointestinal disorders,
respiratory and pulmonary disorders, cardiovascular
disorders, hematologic disorders, reproductive disorders,
ocular disorders, dermatologic disorders, psychological
disorders, and musculoskeletal disorders. A medical diagnostic apparatus for detecting and testing DNA
and RNA; medical diagnostic apparatus for preventing,
detecting and reporting existence or symptoms of disease in
the nature of endocrine disorders, metabolic disorders
including obesity, oncologic disorders, renal disorders,
urologic disorders, hepatic disorders, disorders of the
nervous system, infectious disorders, immunologic disorders,
gastrointestinal disorders, respiratory and pulmonary
disorders, cardiovascular disorders, hematologic disorders,
reproductive disorders, ocular disorders, dermatologic
disorders, psychological disorders, and musculoskeletal
disorders. Providing medical and scientific research information via
the internet; research and development of new products.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable medical software for testing and
detection of DNA and RNA; recorded or downloadable medical
software for diagnosing and reporting the existence or
symptoms of disease in the nature of endocrine disorders,
metabolic disorders including obesity, oncologic disorders,
renal disorders, urologic disorders, hepatic disorders,
disorders of the nervous system, infectious disorders,
immunologic disorders, gastrointestinal disorders,
respiratory and pulmonary disorders, cardiovascular
disorders, hematologic disorders, reproductive disorders,
ocular disorders, dermatologic disorders, psychological
disorders, and musculoskeletal disorders. A medical diagnostic apparatus for detecting and testing DNA
and RNA; medical diagnostic apparatus for preventing,
detecting and reporting existence or symptoms of disease in
the nature of endocrine disorders, metabolic disorders
including obesity, oncologic disorders, renal disorders,
urologic disorders, hepatic disorders, disorders of the
nervous system, infectious disorders, immunologic disorders,
gastrointestinal disorders, respiratory and pulmonary
disorders, cardiovascular disorders, hematologic disorders,
reproductive disorders, ocular disorders, dermatologic
disorders, psychological disorders, and musculoskeletal
disorders. Providing medical and scientific research information via
the internet; research and development of new products.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable medical software for testing and
detection of DNA and RNA; recorded or downloadable medical
software for diagnosing and reporting the existence or
symptoms of disease in the nature of endocrine disorders,
metabolic disorders including obesity, oncologic disorders,
renal disorders, urologic disorders, hepatic disorders,
disorders of the nervous system, infectious disorders,
immunologic disorders, gastrointestinal disorders,
respiratory and pulmonary disorders, cardiovascular
disorders, hematologic disorders, reproductive disorders,
ocular disorders, dermatologic disorders, psychological
disorders, and musculoskeletal disorders. A medical diagnostic apparatus for detecting and testing DNA
and RNA; medical diagnostic apparatus for preventing,
detecting and reporting existence or symptoms of disease in
the nature of endocrine disorders, metabolic disorders
including obesity, oncologic disorders, renal disorders,
urologic disorders, hepatic disorders, disorders of the
nervous system, infectious disorders, immunologic disorders,
gastrointestinal disorders, respiratory and pulmonary
disorders, cardiovascular disorders, hematologic disorders,
reproductive disorders, ocular disorders, dermatologic
disorders, psychological disorders, and musculoskeletal
disorders. Providing medical and scientific research information via
the internet; research and development of new products.
42 - Scientific, technological and industrial services, research and design
Goods & Services
A medical diagnostic device for testing genetic material; a
medical device and software sold as a unit for nucleic acid
detection; medical diagnostic apparatus for detecting
disease. Providing medical and scientific research information via
the internet; research and development of new products.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Recorded and downloadable medical software for testing and detection of DNA and RNA; recorded and downloadable medical software for diagnosing and reporting the existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders.
(2) Medical devices for the qualitative detection and testing of DNA and RNA in human specimens for the detection of Covid-19, Flu A/B and RSV; diagnostic biomarker testing apparatus for preventing, detecting and reporting existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders. (1) Providing medical and scientific research information relating to infectious disease detection via the internet; research and developments of new products relating to infectious disease detection; providing medical and scientific research information in the field of pharmaceutical and clinical trials; medical research and development of new products for others.
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Medical devices for the qualitative detection and testing of DNA and RNA in human specimens for the detection of Covid-19, Flu A/B and RSV, and nucleic acid detection. (1) Providing medical and scientific research information in the field of pharmaceutical and clinical trials; medical research and development of new products for others; providing medical and scientific research information relating to infectious disease detection via the internet; research and developments of new products relating to infectious disease detection.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Recorded and downloadable medical software for testing and detection of DNA and RNA; recorded and downloadable medical software for diagnosing and reporting the existences and symptoms of disease in the nature of endocrine disorders, metabolic disorders namely obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders.
(2) A medical diagnostic apparatus for detecting and testing DNA and RNA; diagnostic biomarker testing apparatus for preventing, detecting and reporting existence and symptoms of disease in the nature of endocrine disorders, metabolic disorders namely obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders. (1) Providing medical and scientific research information relating to infectious disease detection via the internet; research and development of new products relating to infectious disease detection; providing medical and scientific research information in the field of pharmaceutical and clinical trials; medical research and development of new products for others.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Recorded or downloadable molecular diagnostic medical software for electronic testing and detection of DNA and RNA by electrical signals, for diagnosing and reporting the existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders.
(2) An electronic molecular diagnostic medical apparatus for electronically detecting and testing DNA and RNA by electrical signals, for preventing, detecting and reporting existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders. (1) Providing medical and scientific research information via the internet; research and development of new products for the monitoring of the medical diagnostic.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Recorded and downloadable medical software for testing and detection of DNA and RNA; recorded and downloaded medical software for diagnosing and reporting the existences and symptoms of disease in the nature of endocrine disorders, metabolic disorders namely obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders.
(2) A medical diagnostic apparatus for detecting and testing DNA and RNA; diagnostic biomarker testing apparatus for preventing, detecting and reporting existence and symptoms of disease in the nature of endocrine disorders, metabolic disorders namely obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders. (1) Providing medical and scientific research information relating to infectious disease detection via the internet; research and development of new products relating to infectious disease detection; providing medical and scientific research information in the field of pharmaceutical and clinical trials; medical research and development of new products for others.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable medical software for testing and detection of DNA and RNA; recorded or downloadable medical software for diagnosing and reporting the existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders A medical diagnostic apparatus for detecting and testing DNA and RNA; medical diagnostic apparatus for preventing, detecting and reporting existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders Providing medical and scientific research information via the internet; research and development of new products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable medical software for testing and detection of DNA and RNA; recorded or downloadable medical software for diagnosing and reporting the existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders A medical diagnostic apparatus for detecting and testing DNA and RNA; medical diagnostic apparatus for preventing, detecting and reporting existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders Providing medical and scientific research information via the internet; research and development of new products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable molecular diagnostic medical software for electronic testing and detection of DNA and RNA by electrical signals, for diagnosing and reporting the existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders An electronic molecular diagnostic medical apparatus for electronically detecting and testing DNA and RNA by electrical signals, for preventing, detecting and reporting existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders Providing medical and scientific research information via the internet; research and development of new products for medical diagnostic monitoring
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Recorded or downloadable medical software for testing and detection of DNA and RNA; recorded or downloadable medical software for diagnosing and reporting the existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders A medical diagnostic apparatus for detecting and testing DNA and RNA; medical diagnostic apparatus for preventing, detecting and reporting existence or symptoms of disease in the nature of endocrine disorders, metabolic disorders including obesity, oncologic disorders, renal disorders, urologic disorders, hepatic disorders, disorders of the nervous system, infectious disorders, immunologic disorders, gastrointestinal disorders, respiratory and pulmonary disorders, cardiovascular disorders, hematologic disorders, reproductive disorders, ocular disorders, dermatologic disorders, psychological disorders, and musculoskeletal disorders Providing medical and scientific research information via the internet; research and development of new products
Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
G01N 33/487 - Physical analysis of biological material of liquid biological material
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
G01N 33/487 - Physical analysis of biological material of liquid biological material
Embodiments provide analyte detection systems and methods for detecting the presence of one or more analytes in one or more samples. In a detection method, a sample and a sensor compound is introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of an analyte in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
G01N 33/487 - Physical analysis of biological material of liquid biological material
Embodiments provide analyte detection systems and methods for detecting the presence of one or more analytes in one or more samples. In a detection method, a sample and a sensor compound is introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of an analyte in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
G01N 33/487 - Physical analysis of biological material of liquid biological material
Embodiments provide mercury detection systems and methods for detecting the presence of mercury ions in one or more samples. In a detection method, a sample and TPET2 molecules are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of mercury ions in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
Embodiments provide silver detection systems and methods for detecting the presence of silver ions in one or more samples. In a detection method, a sample and TPEA2 molecules are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of silver ions in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/49 - Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
G01R 17/02 - Arrangements in which the value to be measured is automatically compared with a reference value
G01N 27/00 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
Embodiments provide analyte detection methods, techniques and processes for detecting the presence of one or more analytes in one or more samples. In a detection method, a sample and a sensor compound is introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of an analyte in the channel is determined based on a comparison between the first and second electrical property values.
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
G01N 33/487 - Physical analysis of biological material of liquid biological material
Embodiments provide analyte detection systems for detecting the presence of one or more analytes in one or more samples. An exemplary detection system includes at least one channel for accommodating a sample and a sensor compound, the channel having a width and a length that is significantly greater in dimension than the width. An exemplary detection system includes an analyte detection circuit programmed or configured to detect one or more electrical properties along at least a portion of the length of the channel to determine whether the channel contains an analyte of interest.
G01N 33/487 - Physical analysis of biological material of liquid biological material
G01N 27/06 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
