Abbott Point Of Care Inc.

United States of America

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Date
2024 March 1
2024 (YTD) 1
2023 4
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IPC Class
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers 96
G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals 56
G01N 33/49 - Physical analysis of biological material of liquid biological material blood 44
G01N 27/327 - Biochemical electrodes 34
G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor 25
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NICE Class
10 - Medical apparatus and instruments 30
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1.

APPARATUS AND DEVICES FOR PROCESSING FLUID SAMPLES

      
Application Number 18516026
Status Pending
Filing Date 2023-11-21
First Publication Date 2024-03-14
Owner Abbott Point of care Inc. (USA)
Inventor Virtanen, Antti

Abstract

Disclosed herein is an apparatus for processing fluid samples such as blood or blood products. Also disclosed are devices comprising the apparatus as well as methods for separating plasma from blood or blood products using said apparatus.

IPC Classes  ?

  • G01N 1/34 - Purifying; Cleaning
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

2.

APPARATUS AND DEVICES FOR PROCESSING FLUID SAMPLES

      
Application Number US2022053129
Publication Number 2023/154110
Status In Force
Filing Date 2022-12-16
Publication Date 2023-08-17
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor Virtanen, Antti

Abstract

Disclosed herein is an apparatus for processing fluid samples such as blood or blood products. Also disclosed are devices comprising the apparatus as well as methods for separating plasma from blood or blood products using said apparatus.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • B32B 7/00 - Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical propert; Layered products characterised by the interconnection of layers
  • G01N 1/34 - Purifying; Cleaning

3.

SYSTEMS AND METHODS FOR DETERMINING UCH-L1, GFAP, AND OTHER BIOMARKERS IN BLOOD SAMPLES

      
Application Number US2022081763
Publication Number 2023/114978
Status In Force
Filing Date 2022-12-16
Publication Date 2023-06-22
Owner
  • ABBOTT LABORATORIES (USA)
  • ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Lee, Tony
  • Karabatsos, Peter
  • Schapals, Andrew
  • Virtanen, Antti
  • Mcquiston, Beth

Abstract

Disclosed herein are systems and methods for determining ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), glial fibrillary acidic protein (GFAP), or a combination thereof in a blood sample obtained from a subject. Also disclosed herein are systems and methods for determining CK-MB, β-hCG, thyroid stimulating hormone (TSH), homocysteine, free thyroxine (free T4) or any combinations thereof in a blood sample.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • B32B 7/00 - Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical propert; Layered products characterised by the interconnection of layers
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • G01N 33/74 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones
  • G01N 33/76 - Human chorionic gonadotropin
  • G01N 33/78 - Thyroid gland hormones

4.

Management System for Point of Care Testing

      
Application Number 17951771
Status Pending
Filing Date 2022-09-23
First Publication Date 2023-03-16
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann
  • Emeric, Pierre
  • Molloy, Dan
  • Weber, Maureen
  • Fetters, Christopher

Abstract

The present invention relates to a method and system for quality compliance, system and operator verification, and process management for point of care biological sample testing systems used in hospitals and other medical delivery environments. Specifically, the present invention may be directed to a computing device configured to generate a plurality of attributes configured to assess a competency level of an operator to operate at least one sample testing instrument, obtain operator derived data pertaining to the operator's ability to operate the at least one sample testing instrument, and determine a competency level of the operator for the at least one sample testing instrument based the plurality of attributes and the operator derived data.

IPC Classes  ?

  • G06Q 10/06 - Resources, workflows, human or project management; Enterprise or organisation planning; Enterprise or organisation modelling
  • G06Q 30/00 - Commerce
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
  • G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
  • G16Z 99/00 - Subject matter not provided for in other main groups of this subclass
  • G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms

5.

METHODS AND SYSTEMS OF DIAGNOSING BRAIN INJURY

      
Application Number US2022075638
Publication Number 2023/034777
Status In Force
Filing Date 2022-08-30
Publication Date 2023-03-09
Owner
  • ABBOTT LABORATORIES (USA)
  • ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Mcquiston, Beth
  • Datwyler, Saul
  • Chandran, Raj

Abstract

Disclosed herein are methods and systems of determining whether a subject's levels of GFAP, UCH-L1, or GFAP and UCH-L1 are elevated in a sample collected from the subject. The methods comprise determining whether the levels of GFAP, UCH-L1, or GFAP and UCH-L1 are elevated in the sample, and communicating the determination on or from an instrument. The methods may be used to aid in the diagnosis and evaluation of a subject (e.g., a human subject) that has sustained or may have sustained an injury to the head, such as to determine whether the subject is suffering from a mild, moderate, severe, or moderate to severe traumatic brain injury (TBI).

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

6.

MAGNETIC IMMUNOSENSOR WITH TRENCH CONFIGURATION AND METHOD OF USE

      
Application Number 17804330
Status Pending
Filing Date 2022-05-27
First Publication Date 2022-10-13
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Campbell, John Lewis Emerson
  • Miller, Cary James

Abstract

The present invention provides apparatus and methods for the rapid determination of analytes in liquid samples by immunoassays incorporating magnetic capture of beads on a sensor capable of being used in the point-of-care diagnostic field.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 27/327 - Biochemical electrodes
  • G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

7.

DEVICES, SYSTEMS, AND METHODS FOR PERFORMING OPTICAL ASSAYS

      
Application Number 17645797
Status Pending
Filing Date 2021-12-23
First Publication Date 2022-04-14
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).

IPC Classes  ?

  • G01N 21/03 - Cuvette constructions
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated

8.

EXTENDED RANGE IMMUNOASSAY DEVICES WITH IMMUNOSENSOR AND MAGNETIC IMMUNOSENSOR

      
Application Number 17451029
Status Pending
Filing Date 2021-10-15
First Publication Date 2022-02-03
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antii Leo Oskari
  • Bezaire, John Wilfrid
  • Potter, Eric Edward
  • Smith, James T.K.
  • Miller, Cary James
  • Campbell, John Lewis Emerson
  • Moss, Adam Roger

Abstract

The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a housing, a heterogeneous surface capture immunosensor within the housing and configured to generate a first signal indicative of the concentration of the analyte in an upper concentration range, and a homogeneous magnetic bead capture immunosensor within the housing and configured to generate a second signal indicative of the concentration of the analyte in a lower concentration range.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 27/327 - Biochemical electrodes
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 33/536 - Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • G01R 33/12 - Measuring magnetic properties of articles or specimens of solids or fluids
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

9.

MICROFABRICATED DEVICE WITH MICRO-ENVIRONMENT SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES

      
Application Number 17475570
Status Pending
Filing Date 2021-09-15
First Publication Date 2022-01-06
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Zhao, Tian-Xian
  • Wong, Anjulia Chiu-Yuk
  • Martin, Glenn Brian
  • Di Tullio, Katrina Petronilla
  • Thibodeau, Isabelle Louisette
  • Breeze, Steven Roy
  • Sutrala, Smitha Rk
  • Hong, Eric
  • Taylor, Jay Kendall
  • Ball, Sheila Diane

Abstract

The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor.

IPC Classes  ?

  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 27/403 - Cells and electrode assemblies
  • G01N 27/416 - Systems

10.

METHODS, COMPLEXES AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF A ß-CORONAVIRUS ANTIBODY IN A SAMPLE

      
Application Number US2021026146
Publication Number 2021/211331
Status In Force
Filing Date 2021-04-07
Publication Date 2021-10-21
Owner
  • ABBOTT POINT OF CARE INC. (USA)
  • ABBOTT LABORATORIES (USA)
Inventor
  • Virtanen, Antti
  • Bezaire, Jake
  • Muerhoff, A. Scott

Abstract

Disclosed herein are methods, complexes, kits, systems and algorithms for detecting or determining an amount, quantity, concentration and/or level of at least one type of anti-β-coronavirus antibody, such as, for example, an anti-SARS-CoV antibody or anti-SARS-CoV-2 antibody (including an IgA, IgG and/or an IgM antibody), in one or more samples obtained from a subject.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

11.

TECHNIQUES FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS WITH UNIVERSAL CIRCUITRY

      
Application Number 17350426
Status Pending
Filing Date 2021-06-17
First Publication Date 2021-10-07
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).

IPC Classes  ?

  • G01N 27/327 - Biochemical electrodes
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
  • G01N 27/27 - Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a furthe
  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers

12.

DEVICES, SYSTEMS, AND METHODS FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS

      
Application Number 17343056
Status Pending
Filing Date 2021-06-09
First Publication Date 2021-09-23
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).

IPC Classes  ?

  • G01N 27/27 - Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a furthe
  • G01N 27/327 - Biochemical electrodes
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
  • G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour

13.

SYSTEMS AND METHODS FOR ASSURING QUALITY COMPLIANCE OF POINT-OF-CARE INSTRUMENTS USED WITH SINGLE-USE TESTING DEVICES

      
Application Number 17225723
Status Pending
Filing Date 2021-04-08
First Publication Date 2021-08-05
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann

Abstract

The present invention relates to systems and methods of determining quality compliance for one or more biological sample testing instruments used with one or more type of single-use blood testing cartridge, at the point-of-care in a hospital, or other location that deliver medical care. In particular, the systems and methods ensure that only instruments that pass a quality assurance protocol are used for point-of-care testing

IPC Classes  ?

  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis

14.

Management system for point of care testing

      
Application Number 17164990
Grant Number 11488088
Status In Force
Filing Date 2021-02-02
First Publication Date 2021-06-17
Grant Date 2022-11-01
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann
  • Emeric, Pierre
  • Molloy, Dan
  • Weber, Maureen
  • Fetters, Christopher

Abstract

The present invention relates to a method and system for quality compliance, system and operator verification, and process management for point of care biological sample testing systems used in hospitals and other medical delivery environments. Specifically, the present invention may be directed to a computing device configured to generate a plurality of attributes configured to assess a competency level of an operator to operate at least one sample testing instrument, obtain operator derived data pertaining to the operator's ability to operate the at least one sample testing instrument, and determine a competency level of the operator for the at least one sample testing instrument based the plurality of attributes and the operator derived data.

IPC Classes  ?

  • G06Q 10/06 - Resources, workflows, human or project management; Enterprise or organisation planning; Enterprise or organisation modelling
  • G06Q 30/00 - Commerce
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
  • G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
  • G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G16Z 99/00 - Subject matter not provided for in other main groups of this subclass

15.

PORTABLE CLINICAL ANALYSIS SYSTEM FOR IMMUNOMETRIC MEASUREMENT

      
Application Number 17164996
Status Pending
Filing Date 2021-02-02
First Publication Date 2021-06-03
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Vandersleen, Gary
  • Emeric, Pierre
  • Wasserman, Paul
  • Soman, Narendra
  • Davis, Graham
  • Miller, Cary

Abstract

The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.

IPC Classes  ?

  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 33/487 - Physical analysis of biological material of liquid biological material
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood

16.

THERMAL CONTROL SYSTEM FOR CONTROLLING THE TEMPERATURE OF A FLUID

      
Application Number 17166215
Status Pending
Filing Date 2021-02-03
First Publication Date 2021-06-03
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Vandersleen, Gary J.
  • Gershtein, Sergey
  • Tilson, Mitchell
  • Patel, Jaymin
  • Schneider, Craig H.
  • Hunter, Seth
  • Wasserman, Paul
  • Emeric, Pierre

Abstract

The invention relates to a thermal control system for controlling the temperature of a fluid. In particular, the invention relates to a control system having at least two heating elements, at least one of which is used for directly or indirectly heating a fluid, and at least one of which is used for heating a thermal probe used to determine the temperature of the fluid. The heating systems are controlled by at least one feedback controller.

IPC Classes  ?

  • B01L 7/00 - Heating or cooling apparatus; Heat insulating devices
  • G05D 23/30 - Automatic controllers with an auxiliary heating device affecting the sensing element, e.g. for anticipating change of temperature

17.

COMBINED IMMUNOASSAY AND MAGNETIC IMMUNOASSAY METHODS FOR EXTENDED RANGE OF SENSITIVITY

      
Application Number 17165282
Status Pending
Filing Date 2021-02-02
First Publication Date 2021-05-27
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James

Abstract

The present invention relates to methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a method includes forming, in a biological sample, a first complex of signal antibodies and analyte, and a second complex of the first complex and capture antibodies immobilized on magnetic beads, and contacting a first immunosensor with the biological sample to form a third complex localized on or near a surface of the first immunosensor. The first immunosensor includes an immobilized layer of capture antibodies configured to bind to the analyte, and the third complex includes the first complex bound to the immobilized layer of capture antibodies. The method further includes contacting a magnetic field localized around a second immunosensor with the biological sample such that the second complex is localized on or near a surface of the second immunosensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/539 - Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent
  • G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

18.

Combined immunoassay and magnetic immunoassay systems and devices for extended range of sensitivity

      
Application Number 17149319
Grant Number 11680944
Status In Force
Filing Date 2021-01-14
First Publication Date 2021-05-06
Grant Date 2023-06-20
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James
  • Hardage, Kenneth Harold

Abstract

The present invention relates to systems that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device is provided for detecting an analyte in a biological sample. The device includes a first electrochemical sensor positioned on a substrate. The first electrochemical sensor includes an immobilized layer of antibody configured to bind to the analyte. The device further includes a second electrochemical sensor positioned adjacent to the first electrochemical sensor on the substrate, and a magnetic material that generates a magnetic field aligned with respect to the second electrochemical sensor. The magnetic field captures magnetic beads that have an immobilized layer of antibody configured to bind to the analyte, and concentrates the magnetic beads on or near a surface of the second electrochemical sensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/549 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic with antigen or antibody entrapped within the carrier
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • C08L 79/08 - Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
  • C01G 53/00 - Compounds of nickel
  • C08L 29/04 - Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
  • G01N 27/327 - Biochemical electrodes
  • C01F 17/30 - Compounds containing rare earth metals and at least one element other than a rare earth metal, oxygen or hydrogen, e.g. La4S3Br6

19.

Methods for assuring quality compliance of point-of-care single-use testing devices

      
Application Number 16725395
Grant Number 11249097
Status In Force
Filing Date 2019-12-23
First Publication Date 2020-04-30
Grant Date 2022-02-15
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann

Abstract

The present invention relates to systems and methods of determining quality compliance for a set of biological sample testing devices used with one or more test instruments at the point-of-care in a hospital or other location that delivers medical care. In particular, the systems and methods ensure that only biological sample testing devices that pass a quality assurance protocol are used for point-of-care testing.

IPC Classes  ?

  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
  • G16Z 99/00 - Subject matter not provided for in other main groups of this subclass

20.

DUAL RANGE CARDIAC TROPONIN IMMUNOASSAY DEVICES AND METHODS USING IMMUNOSENSOR AND MAGNETIC IMMUNOSENSOR

      
Application Number 16679470
Status Pending
Filing Date 2019-11-11
First Publication Date 2020-03-05
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Potter, Eric Edward
  • Smith, James T.K.
  • Miller, Cary James
  • Campbell, John Lewis Emerson
  • Moss, Adam Roger

Abstract

The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a first immunosensor including an immobilized layer of capture antibodies configured to bind to a first complex of signal antibodies and cardiac troponin such that a second complex of the first complex and the immobilized layer of capture antibodies is localized on or near the first immunosensor. The device further includes a second immunosensor having a magnetic field disposed locally around the second immunosensor. The magnetic field is configured to attract magnetic beads such that a third complex of the first complex and capture antibodies immobilized on the magnetic beads is localized on or near the second immunosensor sensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
  • G01N 33/539 - Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent

21.

Cartridge device with bypass channel for mitigating drift of fluid samples

      
Application Number 16426473
Grant Number 11198123
Status In Force
Filing Date 2019-05-30
First Publication Date 2020-01-02
Grant Date 2021-12-14
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Sabourin, David
  • Villeneuve, Alain
  • Hendry, Bruce
  • Chung, Jessica
  • Garrett, Graham E.
  • Govindaraj, Vinoth Kumar
  • Di Tullio, Katrina Petronilla
  • Ball, Sheila Diane

Abstract

The present disclosure relates to analytical testing devices comprising microfluidics and methods for performing an assay on a fluid sample received within the microfluidics, and in particular, to mitigating drift of fluid samples over a sensor by incorporating a bypass channel into the microfluidics. For example, a test cartridge device is provided that includes a fluid sample entry port and holding chamber connected to a bifurcation junction of a sensor channel and a bypass channel. The sensor channel includes an upstream region and a downstream region, and an analyte sensor is in the upstream region. As a cross-sectional area of the bypass channel is greater than the cross-sectional area of the downstream region of the sensor channel, the bypass channel is a preferred path for excess sample flow and pressure, and thus sample drift above the analyte sensor is mitigated.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements

22.

CARTRIDGE DEVICE WITH BYPASS CHANNEL FOR MITIGATING DRIFT OF FLUID SAMPLES

      
Application Number US2019034624
Publication Number 2020/005455
Status In Force
Filing Date 2019-05-30
Publication Date 2020-01-02
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Sabourin, David
  • Villeneuve, Alain
  • Hendry, Bruce
  • Chung, Jessica
  • Garrett, Graham E.
  • Govindaraj, Vinoth Kumar
  • Di Tullio, Katrina Petronilla
  • Ball, Sheila Diane

Abstract

The present disclosure relates to analytical testing devices comprising microfluidics and methods for performing an assay on a fluid sample received within the microfluidics, and in particular, to mitigating drift of fluid samples over a sensor by incorporating a bypass channel into the microfluidics. For example, a test cartridge device is provided that includes a fluid sample entry port and holding chamber connected to a bifurcation junction of a sensor channel and a bypass channel. The sensor channel includes an upstream region and a downstream region, and an analyte sensor is in the upstream region. As a cross-sectional area of the bypass channel is greater than the cross-sectional area of the downstream region of the sensor channel, the bypass channel is a preferred path for excess sample flow and pressure, and thus sample drift above the analyte sensor is mitigated.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time

23.

Biologic fluid analysis cartridge with sample handling portion and analysis chamber portion

      
Application Number 16551151
Grant Number 11583851
Status In Force
Filing Date 2019-08-26
First Publication Date 2019-12-12
Grant Date 2023-02-21
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Verrant, John A.
  • Lalpuria, Niten V.
  • Nikonorov, Igor
  • Unfricht, Darryn W.
  • Ports, Benjamin
  • Wardlaw, Stephen C.
  • Levine, Robert A.
  • Holt, Robert
  • Hukari, Kyle

Abstract

A biological fluid analysis cartridge is provided. In certain embodiments, the cartridge includes a base plate extending between a sample handling portion and an analysis chamber portion. A handling upper panel is attached to the base plate within the sample handling portion. A collection port is at least partially formed with the handling upper panel. An initial channel and a secondary channel are formed between the handling upper panel and the base plate. The collection port and initial and secondary channels are in fluid communication with one another. A chamber upper panel is attached to the base plate within the analysis chamber portion. At least one analysis chamber is formed between the chamber upper panel and the base plate. The secondary channel and the analysis chamber are in fluid communication with one another.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

24.

Integrated cartridge housings for sample analysis

      
Application Number 16526275
Grant Number 10828642
Status In Force
Filing Date 2019-07-30
First Publication Date 2019-11-21
Grant Date 2020-11-10
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Doyle, Kevin John
  • Wilkins, Paul
  • Withers, Mick
  • Cooper, Adrian
  • Noell, John Oakey

Abstract

The invention relates to a cartridge housing for forming a cartridge capable of measuring an analyte or property of a liquid sample. The housing including a top portion having a first substantially rigid zone and a substantially flexible zone, a bottom portion separate from the top portion including a second substantially rigid zone, and at least one sensor recess containing a sensor. The top portion and the bottom portion are bonded to form the cartridge having a conduit over at least a portion of the sensor. The invention also relates to methods for forming such cartridges and to various features of such cartridges.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

25.

Method and apparatus for automated whole blood sample analyses from microscopy images

      
Application Number 16524422
Grant Number 10677711
Status In Force
Filing Date 2019-07-29
First Publication Date 2019-11-14
Grant Date 2020-06-09
Owner Abbott Point of Care, Inc. (USA)
Inventor
  • Herzog, David
  • Wang, Zhizhou
  • Wardlaw, Stephen C.
  • Xie, Min

Abstract

An apparatus and a method for identifying at least one type of white blood cell (WBC) within a whole blood sample is provided. The method includes: adding at least one colorant to the sample; providing at least one fluorescent excitation light and at least one transmission light; receiving both light fluorescing from and transmitted through the sample and producing signals representative thereof; creating at least one image of the sample using the signals; identifying WBCs within the sample image; quantitatively analyzing at least some of the identified WBCs within the image, including determining one or more quantitative values; and identifying at least one type of WBC from the identified WBCs using the quantitative values.

IPC Classes  ?

  • G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
  • G01N 21/03 - Cuvette constructions
  • G01N 15/14 - Electro-optical investigation
  • G01N 21/59 - Transmissivity
  • G01N 21/64 - Fluorescence; Phosphorescence
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 15/00 - Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials

26.

Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples

      
Application Number 16259500
Grant Number 11156620
Status In Force
Filing Date 2019-01-28
First Publication Date 2019-05-23
Grant Date 2021-10-26
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Zhao, Tian-Xian
  • Wong, Anjulia Chiu-Yuk
  • Martin, Glenn Brian
  • Di Tullio, Katrina Petronilla
  • Thibodeau, Isabelle Louisette
  • Breeze, Steven Roy
  • Sutrala, Smitha R K
  • Hong, Eric
  • Taylor, Jay Kendall
  • Ball, Sheila Diane

Abstract

The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor.

IPC Classes  ?

  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 27/403 - Cells and electrode assemblies
  • G01N 27/416 - Systems
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

27.

Techniques for performing optical and electrochemical assays with universal circuitry

      
Application Number 16104204
Grant Number 11060994
Status In Force
Filing Date 2018-08-17
First Publication Date 2019-02-21
Grant Date 2021-07-13
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).

IPC Classes  ?

  • G01N 27/327 - Biochemical electrodes
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
  • G01N 27/27 - Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a furthe
  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
  • G01N 27/07 - Construction of measuring vessels; Electrodes therefor
  • G01N 27/416 - Systems

28.

Devices, systems, and methods for performing optical assays

      
Application Number 16104232
Grant Number 11253852
Status In Force
Filing Date 2018-08-17
First Publication Date 2019-02-21
Grant Date 2022-02-22
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 33/487 - Physical analysis of biological material of liquid biological material
  • G01N 27/327 - Biochemical electrodes
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
  • G01N 27/416 - Systems
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

29.

TECHNIQUES FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS WITH UNIVERSAL CIRCUITRY

      
Application Number IB2018056232
Publication Number 2019/035082
Status In Force
Filing Date 2018-08-17
Publication Date 2019-02-21
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

Devices, systems, and methods for performing optical and electrochemical assays are disclosed, more particularly, devices and systems having universal channel circuitry (245, 1000) configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin (1063, 1065, 1070), and thus any sensor contact pad in a testing device (1062), can be connected to one or more channels (1005) capable of taking on one or more measurement modes or configurations, e.g. an amperometric measurement mode or a current drive mode.

IPC Classes  ?

  • G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 27/07 - Construction of measuring vessels; Electrodes therefor
  • G01N 27/327 - Biochemical electrodes

30.

A SINGLE-USE TEST DEVICE FOR IMAGING BLOOD CELLS

      
Application Number IB2018056234
Publication Number 2019/035084
Status In Force
Filing Date 2018-08-17
Publication Date 2019-02-21
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor Gershtein, Sergey

Abstract

This present invention relates generally to devices, systems, and methods for performing bioimaging at the microscopic scale and, more particularly, to devices and systems including a disposable testing device configured to perform bioimaging at the microscopic scale, and methods of performing the bioimaging using the disposable testing device. In some aspects, a testing device is provided for imaging blood cells in a blood sample. The testing device having a sample entry port for receiving the blood sample; a sample testing conduit fluidically connected to the sample entry port, the sample testing conduit including: (i) a planar member, (ii) a transparent planar member, and (iii) a plurality of spacer elements having an average spacer height and disposed between the planar member and the transparent planar member; and an imager chip forming at least a portion of the planar member.

IPC Classes  ?

31.

A SINGLE-USE TEST DEVICE FOR IMAGING ASSAY BEADS

      
Application Number IB2018056236
Publication Number 2019/035086
Status In Force
Filing Date 2018-08-17
Publication Date 2019-02-21
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Gershtein, Sergey
  • Bates, Matt
  • Sabourin, David
  • Yoshimura, Toru

Abstract

This present invention relates generally to devices, systems, and methods for performing bioimaging at the microscopic scale and, more particularly, to devices and systems including a disposable testing device configured to perform bioimaging at the microscopic scale, and methods of performing the bioimaging using the disposable testing device. In some aspects, a testing device is provided for imaging assay beads. The testing device having a sample entry port for receiving the blood sample; a sample testing conduit fluidically connected to the sample entry port, the sample testing conduit including: (i) a planar member, (ii) a transparent planar member, and (iii) a plurality of wells having a predetermined average well height and disposed between the first planar member and the second planar member; and an imager chip forming at least a portion of the planar member.

IPC Classes  ?

32.

A METHOD OF IMAGING ASSAY BEADS IN A BIOLOGICAL SAMPLE

      
Application Number IB2018056237
Publication Number 2019/035087
Status In Force
Filing Date 2018-08-17
Publication Date 2019-02-21
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Gershtein, Sergey
  • Bates, Matt
  • Sabourin, David
  • Yoshimura, Toru

Abstract

This present invention relates generally to devices, systems, and methods for performing bioimaging at the microscopic scale and, more particularly, to devices and systems including a disposable testing device configured to perform bioimaging at the microscopic scale, and methods of performing the bioimaging using the disposable testing device. In some aspects, a method is provided for imaging assay beads. The method includes moving a blood sample into a sample testing conduit having a first wall formed from at least a portion of an imager chip, a second wall formed from a transparent material layer, and a plurality of wells. The method further including driving a light emitter to project light through the wells, recording an output signal of at least one of absorbance and fluorescence, and converting the output signal to a value indicative of a reaction of a biological sample within each of the plurality of wells.

IPC Classes  ?

33.

Devices, systems, and methods for performing optical and electrochemical assays

      
Application Number 16104213
Grant Number 11067526
Status In Force
Filing Date 2018-08-17
First Publication Date 2019-02-21
Grant Date 2021-07-20
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

This present invention relates generally to devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin, and thus any sensor contact pad in a testing device, can be connected to one or more channels capable of taking on one or more measurement modes or configurations (e.g., an amperometric measurement mode or a current drive mode).

IPC Classes  ?

  • G01N 27/27 - Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a furthe
  • G01N 27/327 - Biochemical electrodes
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
  • G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour

34.

DEVICES, SYSTEMS, AND METHODS FOR PERFORMING OPTICAL ASSAYS

      
Application Number IB2018056227
Publication Number 2019/035077
Status In Force
Filing Date 2018-08-17
Publication Date 2019-02-21
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

Devices, systems, and methods for performing optical and electrochemical assays are disclosed, more particularly, devices and systems having universal channel circuitry (245, 1000) configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin (1063, 1065, 1070), and thus any sensor contact pad in a testing device (1062), can be connected to one or more channels (1005) capable of taking on one or more measurement modes or configurations, e.g. an amperometric measurement mode or a current drive mode.

IPC Classes  ?

  • G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 27/327 - Biochemical electrodes

35.

DEVICES, SYSTEMS, AND METHODS FOR PERFORMING OPTICAL AND ELECTROCHEMICAL ASSAYS

      
Application Number IB2018056229
Publication Number 2019/035079
Status In Force
Filing Date 2018-08-17
Publication Date 2019-02-21
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Low, Michael Louie
  • Bass, Barry
  • Gershtein, Sergey

Abstract

Devices, systems, and methods for performing optical and electrochemical assays and, more particularly, to devices and systems having universal channel circuitry (245, 1000) configured to perform optical and electrochemical assays, and methods of performing the optical and electrochemical assays using the universal channel circuitry. The universal channel circuitry is circuitry that has electronic switching capabilities such that any contact pin (1063, 1065, 1070), and thus any sensor contact pad in a testing device (1062), can be connected to one or more channels (1005) capable of taking on one or more measurement modes or configurations, e.g. an amperometric measurement mode or a current drive mode.

IPC Classes  ?

  • G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 27/327 - Biochemical electrodes

36.

A METHOD OF IMAGING BLOOD CELLS

      
Application Number IB2018056235
Publication Number 2019/035085
Status In Force
Filing Date 2018-08-17
Publication Date 2019-02-21
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor Gershtein, Sergey

Abstract

Devices, systems, and methods for performing bioimaging at the microscopic scale are disclosed, more particularly, devices and systems including a disposable testing device (105) configured to perform bioimaging at the microscopic scale, and methods of performing the bioimaging using the disposable testing device (105). A method is provided for performing a differential blood cell count. The method includes moving a blood sample into a sample testing conduit (525) having a first wall formed from at least a portion of an imager chip (505), a second wall formed from a transparent material layer (540), and a plurality of spacer elements (815). The method further including driving a light emitter (555) to project light through the chamber (550), recording an output signal of at least one of absorbance and fluorescence, and converting the output signal to a number count or percentage for each type of cell in the blood sample.

IPC Classes  ?

  • G01N 21/03 - Cuvette constructions
  • G01N 21/64 - Fluorescence; Phosphorescence
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
  • G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated

37.

Method for imaging biologic fluid samples using a predetermined distribution

      
Application Number 16102036
Grant Number 10627390
Status In Force
Filing Date 2018-08-13
First Publication Date 2018-12-06
Grant Date 2020-04-21
Owner Abbott Point of Care, Inc. (USA)
Inventor
  • Xie, Min
  • Wardlaw, Stephen C.

Abstract

A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.

IPC Classes  ?

  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
  • G01N 15/02 - Investigating particle size or size distribution
  • G01N 15/14 - Electro-optical investigation
  • G01N 21/64 - Fluorescence; Phosphorescence
  • G01N 15/00 - Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
  • G01N 33/483 - Physical analysis of biological material

38.

Optical assay device with pneumatic sample actuation

      
Application Number 16047249
Grant Number 10852299
Status In Force
Filing Date 2018-07-27
First Publication Date 2018-11-29
Grant Date 2020-12-01
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Emeric, Pierre
  • Davis, Graham
  • Ewart, Thomas
  • Gershtein, Sergey

Abstract

This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to test devices, e.g., cartridges, methods and systems, wherein the test devices have an entry port configured to receive a test sample into a holding chamber; a first conduit having at least one lateral flow test strip; and a displacement device, such as a pneumatic pump, configured to move a portion of said test sample from said holding chamber into said first conduit. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.

IPC Classes  ?

  • G01N 33/558 - Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/76 - Human chorionic gonadotropin

39.

Cartridge device with fluidic junctions for coagulation assays in fluid samples

      
Application Number 16035102
Grant Number 11391747
Status In Force
Filing Date 2018-07-13
First Publication Date 2018-11-08
Grant Date 2022-07-19
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Di Tullio, Katrina Petronilla
  • Taylor, Jay Kendall
  • Lee-Yow, Niko Daniel
  • Ball, Sheila Diane
  • Campbell, John Lewis Emerson

Abstract

The present invention relates to analytical testing devices comprising fluidic junctions and methods for assaying coagulation in a fluid sample received within the fluidic junctions. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a second reagent, a second sensor region, and a second fluidic lock valve. The sample analysis cartridge further includes a pump configured to push the first segment over the first sensor region to the first fluidic lock valve, and push the second segment over the second sensor region to the second fluidic lock valve.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 27/416 - Systems

40.

Operation and verification of a portable clinical analysis system

      
Application Number 15953671
Grant Number 10877019
Status In Force
Filing Date 2018-04-16
First Publication Date 2018-08-23
Grant Date 2020-12-29
Owner Abbott Point of Care, Inc. (USA)
Inventor
  • Vandersleen, Gary
  • Emeric, Pierre
  • Wasserman, Paul
  • Soman, Narendra
  • Davis, Graham
  • Fetters, Christopher

Abstract

The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.

IPC Classes  ?

  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
  • G01N 33/487 - Physical analysis of biological material of liquid biological material
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 27/327 - Biochemical electrodes

41.

Magnetic immunosensor and method of use

      
Application Number 15938141
Grant Number 10145843
Status In Force
Filing Date 2018-03-28
First Publication Date 2018-08-02
Grant Date 2018-12-04
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Miller, Cary James
  • Hu, Jinghua

Abstract

The present invention provides apparatus and methods for the rapid determination of analytes in liquid samples by immunoassays incorporating magnetic capture of beads on a sensor capable of being used in the point-of-care diagnostic field.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

42.

Ellagic acid formulations for use in coagulation assays

      
Application Number 15912967
Grant Number 10746749
Status In Force
Filing Date 2018-03-06
First Publication Date 2018-07-12
Grant Date 2020-08-18
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Collier, Gordon Bruce
  • Johns, Paul Willis
  • Sutrala, Smitha R K
  • Wang, Dan
  • Di Tullio, Katrina Petronilla

Abstract

The present invention relates to ellagic acid formulations for performing coagulation assays that are highly stable for long term storage and reduce assay time. Particularly, aspects of the present invention are directed to a composition and method of preparing ellagic acid in a highly soluble format for use in a coagulation assay. For example, the ellagic acid may be solubilized in one or more of sodium hydroxide, methanol, a polyether compound, particularly polyethylene glycol, polyethylene oxide, or polyoxyethylene, and a cyclodextrin guest-host complex.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time

43.

Portable clinical analysis system for hematocrit measurement

      
Application Number 15908202
Grant Number 10188327
Status In Force
Filing Date 2018-02-28
First Publication Date 2018-07-05
Grant Date 2019-01-29
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Vandersleen, Gary
  • Emeric, Pierre
  • Wasserman, Paul
  • Soman, Narendra
  • Davis, Graham
  • Zhao, Tian-Xian
  • Glavina, Paul

Abstract

The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.

IPC Classes  ?

  • A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
  • G01N 33/487 - Physical analysis of biological material of liquid biological material
  • G01N 27/327 - Biochemical electrodes

44.

COMBINED IMMUNOASSAY AND MAGNETIC IMMUNOASSAY SYSTEMS AND DEVICES FOR EXTENDED RANGE OF SENSITIVITY

      
Document Number 03046012
Status Pending
Filing Date 2017-12-08
Open to Public Date 2018-06-14
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James
  • Hardage, Kenneth Harold

Abstract

The present invention relates to systems that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device is provided for detecting an analyte in a biological sample. The device includes a first electrochemical sensor positioned on a substrate. The first electrochemical sensor includes an immobilized layer of antibody configured to bind to the analyte. The device further includes a second electrochemical sensor positioned adjacent to the first electrochemical sensor on the substrate, and a magnetic material that generates a magnetic field aligned with respect to the second electrochemical sensor. The magnetic field captures magnetic beads that have an immobilized layer of antibody configured to bind to the analyte, and concentrates the magnetic beads on or near a surface of the second electrochemical sensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

45.

Extended range immunoassay devices with immunosensor and magnetic immunosensor

      
Application Number 15836216
Grant Number 11156607
Status In Force
Filing Date 2017-12-08
First Publication Date 2018-06-14
Grant Date 2021-10-26
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Bezaire, John Wilfrid
  • Potter, Eric Edward
  • Smith, James T. K.
  • Miller, Cary James
  • Campbell, John Lewis Emerson
  • Moss, Adam Roger

Abstract

The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a housing, a heterogeneous surface capture immunosensor within the housing and configured to generate a first signal indicative of the concentration of the analyte in an upper concentration range, and a homogeneous magnetic bead capture immunosensor within the housing and configured to generate a second signal indicative of the concentration of the analyte in a lower concentration range.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • G01N 33/536 - Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
  • G01N 27/327 - Biochemical electrodes
  • G01R 33/12 - Measuring magnetic properties of articles or specimens of solids or fluids
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids

46.

Ameliorated crosstalk immunoassay test device for determining a concentration of an analyte

      
Application Number 15836335
Grant Number 10935511
Status In Force
Filing Date 2017-12-08
First Publication Date 2018-06-14
Grant Date 2021-03-02
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James
  • Hardage, Kenneth Harold

Abstract

The present invention relates to systems that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a first electrochemical sensor positioned within a conduit adjacent to a second electrochemical sensor and spaced apart from one another at a predetermined distance. The first electrochemical sensor includes an immobilized layer of antibodies. The second electrochemical sensor includes a magnetic field disposed locally around the second electrochemical sensor, and the magnetic field is configured to attract magnetic beads onto a surface of the second electrochemical sensor. The device further includes a scavenging electrode positioned between the first electrochemical sensor and the second electrochemical sensor. The scavenging electrode is configured to prevent crosstalk between the first electrochemical immunosensor and the second electrical immunosensor.

IPC Classes  ?

  • G01N 27/27 - Association of two or more measuring systems or cells, each measuring a different parameter, where the measurement results may be either used independently, the systems or cells being physically associated, or combined to produce a value for a furthe
  • G01N 27/327 - Biochemical electrodes
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

47.

Sensors for assaying coagulation in fluid samples

      
Application Number 15879714
Grant Number 10352951
Status In Force
Filing Date 2018-01-25
First Publication Date 2018-06-14
Grant Date 2019-07-16
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Zhao, Tian-Xian
  • Wong, Anjulia Chiu-Yuk
  • Martin, Glenn Brian
  • Di Tullio, Katrina Petronilla
  • Thibodeau, Isabelle Louisette
  • Breeze, Steven Roy
  • Sutrala, Smitha R K
  • Hong, Eric
  • Ball, Sheila Diane

Abstract

The present invention relates to analytical testing devices including micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, performing one or more types of coagulation assays using one or more micro-environment sensors in a single point of care combined test cartridge. For example, the present invention may be directed to test sensor including at least one transducer coated with a polymer layer. The polymer layer comprises a thrombin-cleavable peptide with a detectable moiety.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time

48.

COMBINED IMMUNOASSAY AND MAGNETIC IMMUNOASSAY METHODS FOR EXTENDED RANGE OF SENSITIVITY

      
Application Number US2017065278
Publication Number 2018/107009
Status In Force
Filing Date 2017-12-08
Publication Date 2018-06-14
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James

Abstract

The present invention relates to methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a method includes forming, in a biological sample, a first complex of signal antibodies and analyte, and a second complex of the first complex and capture antibodies immobilized on magnetic beads, and contacting a first immunosensor with the biological sample to form a third complex localized on or near a surface of the first immunosensor. The first immunosensor includes an immobilized layer of capture antibodies configured to bind to the analyte, and the third complex includes the first complex bound to the immobilized layer of capture antibodies. The method further includes contacting a magnetic field localized around a second immunosensor with the biological sample such that the second complex is localized on or near a surface of the second immunosensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

49.

CROSSOVER ANALYTICAL SYSTEMS AND METHODS USING AN IMMUNOSENSOR AND MAGNETIC IMMUNOSENSOR

      
Application Number US2017065282
Publication Number 2018/107012
Status In Force
Filing Date 2017-12-08
Publication Date 2018-06-14
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James
  • Campbell, John Lewis Emerson
  • Moss, Adam Roger

Abstract

The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a method includes determining a first concentration of an analyte at a first immunosensor from a reaction of a signal agent with a first complex of signal antibodies, the analyte, and capture antibodies immobilized on a surface of the first immunosensor, determining a second concentration of the analyte at a second immunosensor from a reaction of the signal agent with a second complex of the signal antibodies, the analyte, and capture antibodies immobilized on magnetic beads that are localized on or near a surface of the second immunosensor via a magnetic field, determining a weighted average of the first concentration and the second concentration, and comparing the weighted average to a predetermined crossover concentration point or zone.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

50.

EXTENDED RANGE IMMUNOASSAY DEVICES WITH IMMUNOSENSOR AND MAGNETIC IMMUNOSENSOR

      
Application Number US2017065286
Publication Number 2018/107015
Status In Force
Filing Date 2017-12-08
Publication Date 2018-06-14
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Bezaire, John Wilfrid
  • Potter, Eric Edward
  • Smith, James T.K.
  • Miller, Cary James
  • Campbell, John Lewis Emerson
  • Moss, Adam Roger

Abstract

The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a housing, a heterogeneous surface capture immunosensor within the housing and configured to generate a first signal indicative of the concentration of the analyte in an upper concentration range, and a homogeneous magnetic bead capture immunosensor within the housing and configured to generate a second signal indicative of the concentration of the analyte in a lower concentration range.

IPC Classes  ?

  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 27/00 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
  • G01N 33/487 - Physical analysis of biological material of liquid biological material
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

51.

AMELIORATED CROSSTALK IMMUNOASSAY TEST DEVICE FOR DETERMINING A CONCENTRATION OF AN ANALYTE

      
Application Number US2017065287
Publication Number 2018/107016
Status In Force
Filing Date 2017-12-08
Publication Date 2018-06-14
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James
  • Hardage, Kenneth Harold

Abstract

The present invention relates to systems that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a first electrochemical sensor positioned within a conduit adjacent to a second electrochemical sensor and spaced apart from one another at a predetermined distance. The first electrochemical sensor includes an immobilized layer of antibodies. The second electrochemical sensor includes a magnetic field disposed locally around the second electrochemical sensor, and the magnetic field is configured to attract magnetic beads onto a surface of the second electrochemical sensor. The device further includes a scavenging electrode positioned between the first electrochemical sensor and the second electrochemical sensor. The scavenging electrode is configured to prevent crosstalk between the first electrochemical immunosensor and the second electrochemical immunosensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 27/00 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
  • G01N 33/487 - Physical analysis of biological material of liquid biological material
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor

52.

Combined immunoassay and magnetic immunoassay systems and devices for extended range of sensitivity

      
Application Number 15835972
Grant Number 10908154
Status In Force
Filing Date 2017-12-08
First Publication Date 2018-06-14
Grant Date 2021-02-02
Owner Abbottt Point of Care Inc. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James
  • Hardage, Kenneth Harold

Abstract

The present invention relates to systems that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device is provided for detecting an analyte in a biological sample. The device includes a first electrochemical sensor positioned on a substrate. The first electrochemical sensor includes an immobilized layer of antibody configured to bind to the analyte. The device further includes a second electrochemical sensor positioned adjacent to the first electrochemical sensor on the substrate, and a magnetic material that generates a magnetic field aligned with respect to the second electrochemical sensor. The magnetic field captures magnetic beads that have an immobilized layer of antibody configured to bind to the analyte, and concentrates the magnetic beads on or near a surface of the second electrochemical sensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/549 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic with antigen or antibody entrapped within the carrier
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • C08L 79/08 - Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
  • C01G 53/00 - Compounds of nickel
  • C08L 29/04 - Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
  • G01N 27/327 - Biochemical electrodes
  • C01F 17/30 - Compounds containing rare earth metals and at least one element other than a rare earth metal, oxygen or hydrogen, e.g. La4S3Br6

53.

Combined immunoassay and magnetic immunoassay methods for extended range of sensitivity

      
Application Number 15836024
Grant Number 10928388
Status In Force
Filing Date 2017-12-08
First Publication Date 2018-06-14
Grant Date 2021-02-23
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James

Abstract

The present invention relates to methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a method includes forming, in a biological sample, a first complex of signal antibodies and analyte, and a second complex of the first complex and capture antibodies immobilized on magnetic beads, and contacting a first immunosensor with the biological sample to form a third complex localized on or near a surface of the first immunosensor. The first immunosensor includes an immobilized layer of capture antibodies configured to bind to the analyte, and the third complex includes the first complex bound to the immobilized layer of capture antibodies. The method further includes contacting a magnetic field localized around a second immunosensor with the biological sample such that the second complex is localized on or near a surface of the second immunosensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/539 - Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent
  • G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

54.

Crossover analytical systems and methods using an immunosensor and magnetic immunosensor

      
Application Number 15836078
Grant Number 10871488
Status In Force
Filing Date 2017-12-08
First Publication Date 2018-06-14
Grant Date 2020-12-22
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James
  • Campbell, John Lewis Emerson
  • Moss, Adam Roger

Abstract

The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a method includes determining a first concentration of an analyte at a first immunosensor from a reaction of a signal agent with a first complex of signal antibodies, the analyte, and capture antibodies immobilized on a surface of the first immunosensor, determining a second concentration of the analyte at a second immunosensor from a reaction of the signal agent with a second complex of the signal antibodies, the analyte, and capture antibodies immobilized on magnetic beads that are localized on or near a surface of the second immunosensor via a magnetic field, determining a weighted average of the first concentration and the second concentration, and comparing the weighted average to a predetermined crossover concentration point or zone.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
  • G01N 33/541 - Double or second antibody

55.

COMBINED IMMUNOASSAY AND MAGNETIC IMMUNOASSAY SYSTEMS AND DEVICES FOR EXTENDED RANGE OF SENSITIVITY

      
Application Number US2017065275
Publication Number 2018/107007
Status In Force
Filing Date 2017-12-08
Publication Date 2018-06-14
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Miller, Cary James
  • Hardage, Kenneth Harold

Abstract

The present invention relates to systems that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device is provided for detecting an analyte in a biological sample. The device includes a first electrochemical sensor positioned on a substrate. The first electrochemical sensor includes an immobilized layer of antibody configured to bind to the analyte. The device further includes a second electrochemical sensor positioned adjacent to the first electrochemical sensor on the substrate, and a magnetic material that generates a magnetic field aligned with respect to the second electrochemical sensor. The magnetic field captures magnetic beads that have an immobilized layer of antibody configured to bind to the analyte, and concentrates the magnetic beads on or near a surface of the second electrochemical sensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

56.

DUAL RANGE CARDIAC TROPONIN IMMUNOASSAY DEVICES AND METHODS USING IMMUNOSENSOR AND MAGNETIC IMMUNOSENSOR

      
Application Number US2017065284
Publication Number 2018/107013
Status In Force
Filing Date 2017-12-08
Publication Date 2018-06-14
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Hu, Jing Hua
  • Virtanen, Antti Leo Oskari
  • Potter, Eric Edward
  • Smith, James T.K.
  • Miller, Cary James
  • Campbell, John Lewis Emerson
  • Moss, Adam Roger

Abstract

The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a first immunosensor including an immobilized layer of capture antibodies configured to bind to a first complex of signal antibodies and cardiac troponin such that a second complex of the first complex and the immobilized layer of capture antibodies is localized on or near the first immunosensor. The device further includes a second immunosensor having a magnetic field disposed locally around the second immunosensor. The magnetic field is configured to attract magnetic beads such that a third complex of the first complex and capture antibodies immobilized on the magnetic beads is localized on or near the second immunosensor sensor.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids

57.

Method for imaging biologic fluid samples using a predetermined distribution

      
Application Number 15886324
Grant Number 10048248
Status In Force
Filing Date 2018-02-01
First Publication Date 2018-06-07
Grant Date 2018-08-14
Owner Abbott Point of Care, Inc. (USA)
Inventor
  • Xie, Min
  • Wardlaw, Stephen C.

Abstract

A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.

IPC Classes  ?

  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 15/14 - Electro-optical investigation
  • G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
  • G01N 15/02 - Investigating particle size or size distribution
  • G01N 15/00 - Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials

58.

Self correction for spatial orientation and motion of portable clinical analyzers

      
Application Number 15877626
Grant Number 10468123
Status In Force
Filing Date 2018-01-23
First Publication Date 2018-06-07
Grant Date 2019-11-05
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Vandersleen, Gary
  • Emeric, Pierre
  • Wasserman, Paul
  • Soman, Narendra
  • Davis, Graham

Abstract

The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.

IPC Classes  ?

  • G16B 99/00 - Subject matter not provided for in other groups of this subclass
  • G01N 27/327 - Biochemical electrodes
  • G01N 33/487 - Physical analysis of biological material of liquid biological material

59.

Portable clinical analysis system for immunometric measurement

      
Application Number 15868549
Grant Number 10942173
Status In Force
Filing Date 2018-01-11
First Publication Date 2018-05-17
Grant Date 2021-03-09
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Vandersleen, Gary
  • Emeric, Pierre
  • Wasserman, Paul
  • Soman, Narendra
  • Davis, Graham
  • Miller, Cary

Abstract

The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.

IPC Classes  ?

  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 33/487 - Physical analysis of biological material of liquid biological material
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor

60.

TNI-NX

      
Application Number 188565800
Status Registered
Filing Date 2018-03-01
Registration Date 2020-03-12
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments

Goods & Services

(1) Cartridges prefilled with medical diagnostic reagents for use in in vitro diagnostic testing; cartridges prefilled with medical diagnostic reagents; medical diagnostic instruments and accessories, namely, apparatus for medical laboratory and clinical use for use in assays for measuring troponin levels; medical diagnostic instruments for medical laboratory and clinical use for use with medical diagnostic reagents and chemical diagnostic reagents

61.

TNI-NX

      
Application Number 188565900
Status Registered
Filing Date 2018-03-01
Registration Date 2019-10-15
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Medical diagnostic reagents; cartridges prefilled with medical diagnostic reagents; assays for measuring troponin levels; in vitro diagnostic tests for the quantitative measurement of cardiac troponin I in whole blood or plasma; medical diagnostic tests for diagnosing myocardial infarction

62.

TNI-NX

      
Application Number 017866880
Status Registered
Filing Date 2018-03-01
Registration Date 2018-09-01
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Control materials for use in in vitro diagnostic testing; diagnostic reagents.

63.

TNI-NX

      
Application Number 017866885
Status Registered
Filing Date 2018-03-01
Registration Date 2018-10-27
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical apparatus in the form of cartridges for containing medical diagnostic reagents for use in in vitro diagnostic testing; medical apparatus in the form of cartridges for containing medical diagnostic reagents; instruments and accessories for use in assays for measuring troponin levels; instruments used with medical diagnostic reagents and chemicals in the healthcare field.

64.

TNI-NX

      
Application Number 188566000
Status Registered
Filing Date 2018-03-01
Registration Date 2020-03-12
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

(1) Control preparations for medical diagnostic instruments used for in vitro diagnostic testing; diagnostic reagents for medical-scientific research use; assays for measuring troponin levels for medical-scientific research use

65.

TNI-NX

      
Application Number 017866882
Status Registered
Filing Date 2018-03-01
Registration Date 2018-08-22
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Medical diagnostic reagents; cartridges prefilled with medical diagnostic reagents; assays for measuring troponin levels; in vitro diagnostic tests for the quantitative measurement of cardiac troponin I in whole blood or plasma; medical diagnostic tests for diagnosing myocardial infarction.

66.

Management system for point of care testing

      
Application Number 15702924
Grant Number 10984366
Status In Force
Filing Date 2017-09-13
First Publication Date 2018-01-04
Grant Date 2021-04-20
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann
  • Emeric, Pierre
  • Molloy, Dan
  • Weber, Maureen
  • Fetters, Christopher

Abstract

The present invention relates to a method and system for quality compliance, system and operator verification, and process management for point of care biological sample testing systems used in hospitals and other medical delivery environments. Specifically, the present invention may be directed to a computing device configured to generate a plurality of attributes configured to assess a competency level of an operator to operate at least one sample testing instrument, obtain operator derived data pertaining to the operator's ability to operate the at least one sample testing instrument, and determine a competency level of the operator for the at least one sample testing instrument based the plurality of attributes and the operator derived data.

IPC Classes  ?

  • G06Q 10/06 - Resources, workflows, human or project management; Enterprise or organisation planning; Enterprise or organisation modelling
  • G06Q 30/00 - Commerce
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
  • G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)

67.

TNINXG

      
Application Number 017240714
Status Registered
Filing Date 2017-09-25
Registration Date 2018-02-15
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Cartridges featuring medical diagnostic reagents for use in in vitro diagnostic testing; cartridges featuring medical diagnostic reagents; instruments and accessories for use in assays for measuring troponin levels; instruments used with medical diagnostic reagents and chemicals in the healthcare field.

68.

TNINXG

      
Application Number 017240681
Status Registered
Filing Date 2017-09-25
Registration Date 2018-01-25
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Medical diagnostic reagents; assays for measuring troponin levels; in vitro diagnostic tests for the quantitative measurement of cardiac troponin I in whole blood or plasma; medical diagnostic tests for diagnosing and treating myocardial infarction/heart attack; medical diagnostic tests to aid in risk stratification of patients with acute coronary syndromes with respect to relative risk of mortality.

69.

TNINXG

      
Application Number 017240839
Status Registered
Filing Date 2017-09-25
Registration Date 2018-02-15
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Controls for use in in vitro diagnostic testing; diagnostic reagents.

70.

Method and apparatus for automated whole blood sample analyses from microscopy images

      
Application Number 15487870
Grant Number 10365203
Status In Force
Filing Date 2017-04-14
First Publication Date 2017-08-03
Grant Date 2019-07-30
Owner Abbott Point of Care, Inc. (USA)
Inventor
  • Herzog, David
  • Wang, Zhizhou
  • Wardlaw, Stephen C.
  • Xie, Min

Abstract

A method and apparatus for identifying one or more target constituents (e.g., white blood cells) within a biological sample is provided. The method includes the steps of: a) adding at least one colorant to the sample; b) disposing the sample into a chamber defined by at least one transparent panel; c) creating at least one image of the sample quiescently residing within the chamber; d) identifying target constituents within the sample image; e) quantitatively analyzing at least some of the identified target constituents within the image relative to one or more predetermined quantitatively determinable features; and f) identifying at least one type of target constituent within the identified target constituents using the quantitatively determinable features.

IPC Classes  ?

  • G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
  • C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
  • G01N 15/14 - Electro-optical investigation
  • G01N 21/59 - Transmissivity
  • G01N 21/64 - Fluorescence; Phosphorescence
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 15/00 - Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials

71.

Integrated cartridge housings for sample analysis

      
Application Number 15419097
Grant Number 10406523
Status In Force
Filing Date 2017-01-30
First Publication Date 2017-05-18
Grant Date 2019-09-10
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Doyle, Kevin John
  • Wilkins, Paul
  • Withers, Mick
  • Cooper, Adrian
  • Noell, John Oakey

Abstract

The invention relates to a cartridge housing for forming a cartridge capable of measuring an analyte or property of a liquid sample. The housing including a top portion having a first substantially rigid zone and a substantially flexible zone, a bottom portion separate from the top portion including a second substantially rigid zone, and at least one sensor recess containing a sensor. The top portion and the bottom portion are bonded to form the cartridge having a conduit over at least a portion of the sensor. The invention also relates to methods for forming such cartridges and to various features of such cartridges.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

72.

Method for imaging biologic fluid samples using a predetermined distribution

      
Application Number 15398299
Grant Number 09885701
Status In Force
Filing Date 2017-01-04
First Publication Date 2017-04-27
Grant Date 2018-02-06
Owner Abbott Point of Care, Inc. (USA)
Inventor
  • Xie, Min
  • Wardlaw, Stephen C.

Abstract

A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample.

IPC Classes  ?

  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
  • G01N 15/02 - Investigating particle size or size distribution
  • G01N 15/14 - Electro-optical investigation
  • G01N 15/00 - Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials

73.

Spatial orientation determination in portable clinical analysis systems

      
Application Number 15291454
Grant Number 09915643
Status In Force
Filing Date 2016-10-12
First Publication Date 2017-02-02
Grant Date 2018-03-13
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Vandersleen, Gary
  • Emeric, Pierre
  • Wasserman, Paul
  • Soman, Narendra
  • Davis, Graham

Abstract

The present invention covers the integration and utility of accelerometer features into a clinical analysis system. For example, measurement of dynamic acceleration and orientation of a blood-testing instrument with respect to Earth's gravitational field may be used to determine reliability of a test procedure and optionally to provide corrective elements thereof.

IPC Classes  ?

  • G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
  • G01N 33/487 - Physical analysis of biological material of liquid biological material
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

74.

Systems and methods for assuring quality compliance of point-of-care instruments used with single-use testing devices

      
Application Number 15145899
Grant Number 11002747
Status In Force
Filing Date 2016-05-04
First Publication Date 2016-12-08
Grant Date 2021-05-11
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann

Abstract

The present invention relates to systems and methods of determining quality compliance for one or more biological sample testing instruments used with one or more type of single-use blood testing cartridge, at the point-of-care in a hospital, or other location that deliver medical care. In particular, the systems and methods ensure that only instruments that pass a quality assurance protocol are used for point-of-care testing.

IPC Classes  ?

  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis

75.

Systems for assuring quality compliance of point-of-care single-use testing devices

      
Application Number 15145934
Grant Number 10557862
Status In Force
Filing Date 2016-05-04
First Publication Date 2016-12-08
Grant Date 2020-02-11
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann

Abstract

The present invention relates to systems and methods of determining quality compliance for a set of biological sample testing devices used with one or more test instruments at the point-of-care in a hospital or other location that delivers medical care. In particular, the systems and methods ensure that only biological sample testing devices that pass a quality assurance protocol are used for point-of-care testing.

IPC Classes  ?

  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis

76.

SYSTEMS AND METHODS FOR ASSURING QUALITY COMPLIANCE OF POINT-OF-CARE SINGLE-USE TESTING DEVICES

      
Application Number US2016030640
Publication Number 2016/195894
Status In Force
Filing Date 2016-05-04
Publication Date 2016-12-08
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann

Abstract

The present invention relates to systems and methods of determining quality compliance for a set of biological sample testing devices used with one or more test instruments at the point-of-care in a hospital or other location that delivers medical care. In particular, the systems and methods ensure that only biological sample testing devices that pass a quality assurance protocol are used for point-of-care testing.

IPC Classes  ?

  • G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)

77.

SYSTEMS AND METHODS FOR ASSURING QUALITY COMPLIANCE OF POINT-OF-CARE INSTRUMENTS USED WITH SINGLE-USE TESTING DEVICES

      
Application Number US2016030647
Publication Number 2016/195896
Status In Force
Filing Date 2016-05-04
Publication Date 2016-12-08
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Glavina, Paul
  • Tirinato, Jody Ann

Abstract

The present invention relates to systems and methods of determining quality compliance for one or more biological sample testing instruments used with one or more type of single-use blood testing cartridge, at the point-of-care in a hospital, or other location that deliver medical care. In particular, the systems and methods ensure that only instruments that pass a quality assurance protocol are used for point-of-care testing

IPC Classes  ?

  • G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)

78.

Optical assay device with pneumatic sample actuation

      
Application Number 15163896
Grant Number 10690664
Status In Force
Filing Date 2016-05-25
First Publication Date 2016-09-15
Grant Date 2020-06-23
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Emeric, Pierre
  • Davis, Graham
  • Ewart, Thomas
  • Gershtein, Sergey

Abstract

This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to test devices, e.g., cartridges, methods and systems, wherein the test devices have an entry port configured to receive a test sample into a holding chamber; a first conduit having at least one lateral flow test strip; and a displacement device, such as a pneumatic pump, configured to move a portion of said test sample from said holding chamber into said first conduit. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/76 - Human chorionic gonadotropin
  • G01N 33/558 - Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

79.

Portable clinical diagnostic instrument

      
Application Number 29523995
Grant Number D0765253
Status In Force
Filing Date 2015-04-15
First Publication Date 2016-08-30
Grant Date 2016-08-30
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Emeric, Pierre
  • Gershtein, Sergey
  • Patel, Jaymin
  • Schneider, Craig
  • Soman, Narendra

80.

Portable clinical diagnostic instrument

      
Application Number 29523978
Grant Number D0765252
Status In Force
Filing Date 2015-04-15
First Publication Date 2016-08-30
Grant Date 2016-08-30
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Emeric, Pierre
  • Gershtein, Sergey
  • Patel, Jaymin
  • Schneider, Craig
  • Soman, Narendra

81.

Oscillating immunoassay method and device

      
Application Number 15086340
Grant Number 10048258
Status In Force
Filing Date 2016-03-31
First Publication Date 2016-07-28
Grant Date 2018-08-14
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Miller, Cary James
  • Campbell, John Lewis Emerson

Abstract

The present invention provides apparatus and methods for the rapid determination of analytes in liquid samples by immunoassays incorporating magnetic capture of beads on a sensor capable of being used in the point-of-care diagnostic field.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

82.

Magnetic immunosensor and method of use

      
Application Number 14976318
Grant Number 09958440
Status In Force
Filing Date 2015-12-21
First Publication Date 2016-04-21
Grant Date 2018-05-01
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Miller, Cary James
  • Hu, Jinghua

Abstract

The present invention provides apparatus and methods for the rapid determination of analytes in liquid samples by immunoassays incorporating magnetic capture of beads on a sensor capable of being used in the point-of-care diagnostic field.

IPC Classes  ?

  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 27/74 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids

83.

Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples

      
Application Number 14866316
Grant Number 10247741
Status In Force
Filing Date 2015-09-25
First Publication Date 2016-03-31
Grant Date 2019-04-02
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Zhao, Tian-Xian
  • Wong, Anjulia Chiu-Yuk
  • Martin, Glenn Brian
  • Di Tullio, Katrina Petronilla
  • Thibodeau, Isabelle Louisette
  • Breeze, Steven Roy
  • Sutrala, Smitha Rk
  • Hong, Eric
  • Taylor, Jay Kendall
  • Ball, Sheila Diane

Abstract

The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor.

IPC Classes  ?

  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 27/403 - Cells and electrode assemblies
  • G01N 27/416 - Systems
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

84.

Cartridge device with segmented fluidics for assaying coagulation in fluid samples

      
Application Number 14866402
Grant Number 10048281
Status In Force
Filing Date 2015-09-25
First Publication Date 2016-03-31
Grant Date 2018-08-14
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Di Tullio, Katrina Petronilla
  • Taylor, Jay Kendall
  • Campbell, John Lewis Emerson
  • Elbuken, Caglar
  • Ball, Shelia Diane
  • Lightstone, Noam Saul

Abstract

The present invention relates to analytical testing devices comprising segmented fluidics and methods for assaying coagulation in a fluid sample received within the segmented fluidics. For example, the present invention may be directed to sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a first flow restrictor region, a second reagent, and a second sensor region. The sample analysis cartridge further includes a pump configured to independently mix the first segment in the second conduit and the second segment in the third conduit, and independently position the first segment over the first sensor region and position the second segment over the second sensor region.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
  • C12Q 1/56 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
  • G01N 31/00 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods
  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time

85.

Cartridge device with fluidic junctions for coagulation assays in fluid samples

      
Application Number 14866432
Grant Number 10048282
Status In Force
Filing Date 2015-09-25
First Publication Date 2016-03-31
Grant Date 2018-08-14
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Di Tullio, Katrina Petronilla
  • Taylor, Jay Kendall
  • Lee-Yow, Niko Daniel
  • Ball, Sheila Diane
  • Campbell, John Lewis Emerson

Abstract

The present invention relates to analytical testing devices comprising fluidic junctions and methods for assaying coagulation in a fluid sample received within the fluidic junctions. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a second reagent, a second sensor region, and a second fluidic lock valve. The sample analysis cartridge further includes a pump configured to push the first segment over the first sensor region to the first fluidic lock valve, and push the second segment over the second sensor region to the second fluidic lock valve.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
  • C12Q 1/56 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
  • G01N 31/00 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods
  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • G01N 27/416 - Systems
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood

86.

Single channel cartridge device for coagulation assays in fluid samples

      
Application Number 14866460
Grant Number 10114031
Status In Force
Filing Date 2015-09-25
First Publication Date 2016-03-31
Grant Date 2018-10-30
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Di Tullio, Katrina Petronilla
  • Taylor, Jay Kendall
  • Lee-Yow, Niko Daniel
  • Ball, Sheila Diane

Abstract

The present invention relates to analytical testing devices comprising a single channel with micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using a single channel with micro-environment sensors in a point of care test cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample and a conduit fluidically connected to the inlet chamber. The conduit includes a sensor chip including a first micro-environment sensor and a second microenvironment sensor, and a fluid lock valve. The sample analysis cartridge further includes a pump configured to push the biological sample over the first micro-environment sensor and the second microenvironment sensor to the fluidic lock valve such that the biological sample is positioned over the first micro-environment sensor and the second micro-environment sensor.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
  • C12Q 1/56 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
  • G01N 31/00 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods
  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • G01N 27/403 - Cells and electrode assemblies
  • G01N 27/416 - Systems
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood

87.

Ellagic acid formulations for use in coagulation assays

      
Application Number 14866518
Grant Number 09921232
Status In Force
Filing Date 2015-09-25
First Publication Date 2016-03-31
Grant Date 2018-03-20
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Collier, Gordon Bruce
  • Johns, Jr., Paul Willis
  • Sutrala, Smitha R K
  • Wang, Dan
  • Di Tullio, Katrina Petronilla

Abstract

The present invention relates to ellagic acid formulations for performing coagulation assays that are highly stable for long term storage and reduce assay time. Particularly, aspects of the present invention are directed to a composition and method of preparing ellagic acid in a highly soluble format for use in a coagulation assay. For example, the ellagic acid may be solubilized in one or more of sodium hydroxide, methanol, a polyether compound, particularly polyethylene glycol, polyethylene oxide, or polyoxyethylene, and a cyclodextrin guest-host complex.

IPC Classes  ?

  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

88.

CARTRIDGE DEVICE WITH SEGMENTED FLUIDICS FOR ASSAYING COAGULATION IN FLUID SAMPLES

      
Application Number US2015052356
Publication Number 2016/049527
Status In Force
Filing Date 2015-09-25
Publication Date 2016-03-31
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Di Tullio, Katrina Petronilla
  • Taylor, Jay Kendall
  • Campbell, John Lewis Emerson
  • Elbuken, Caglar
  • Ball, Sheila Diane
  • Lightstone, Noam Saul

Abstract

The present invention relates to analytical testing devices comprising segmented fluidics and methods for assaying coagulation in a fluid sample received within the segmented fluidics. For example, the present invention may be directed to sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a first flow restrictor region, a second reagent, and a second sensor region. The sample analysis cartridge further includes a pump configured to independently mix the first segment in the second conduit and the second segment in the third conduit, and independently position the first segment over the first sensor region and position the second segment over the second sensor region.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

89.

CARTRIDGE DEVICE IDENTIFICATION FOR COAGULATION ASSAYS IN FLUID SAMPLES

      
Application Number US2015052399
Publication Number 2016/049552
Status In Force
Filing Date 2015-09-25
Publication Date 2016-03-31
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Taylor, Jay Kendall
  • Zhao, Tian-Xian
  • Ball, Sheila Diane
  • Hardage, Kenneth Harold
  • Breeze, Steven Roy
  • Newlands, Joshua David

Abstract

The present invention relates to analytical testing devices comprising a resistor for cartridge device identification and methods for assaying coagulation in a fluid sample based on the cartridge device identification, and in particular, to performing coagulation assays using a resistor for cartridge device identification in a point of care test cartridge. For example, the present invention may be directed to a chip including an analyte electrode connected to a first connection pin, a reference electrode connected to a second connection pin, and a resistor connected to the second connection pin and a third connection pin.

IPC Classes  ?

  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

90.

Sensors for assaying coagulation in fluid samples

      
Application Number 14866266
Grant Number 09903877
Status In Force
Filing Date 2015-09-25
First Publication Date 2016-03-31
Grant Date 2018-02-27
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Zhao, Tian-Xian
  • Wong, Anjulia Chiu-Yuk
  • Martin, Glenn Brian
  • Di Tullio, Katrina Petronilla
  • Thibodeau, Isabelle Louisette
  • Breeze, Steven Roy
  • Sutrala, Smitha R K
  • Hong, Eric
  • Ball, Sheila Diane

Abstract

The present invention relates to analytical testing devices including micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, performing one or more types of coagulation assays using one or more micro-environment sensors in a single point of care combined test cartridge. For example, the present invention may be directed to test sensor including at least one transducer coated with a polymer layer. The polymer layer comprises a thrombin-cleavable peptide with a detectable moiety.

IPC Classes  ?

  • C12Q 1/56 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

91.

SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES

      
Application Number US2015052317
Publication Number 2016/049506
Status In Force
Filing Date 2015-09-25
Publication Date 2016-03-31
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Zhao, Tian-Xian
  • Wong, Anjulia Chiu-Yuk
  • Martin, Glenn Brian
  • Di Tullio, Katrina Petronilla
  • Thibodeau, Isabelle Louisette
  • Breeze, Steven Roy
  • Sutrala, Smitha Rk
  • Hong, Eric
  • Ball, Sheila Diane

Abstract

The present invention relates to analytical testing devices including micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, performing one or more types of coagulation assays using one or more micro-environment sensors in a single point of care combined test cartridge. For example, the present invention may be directed to test sensor including at least one transducer coated with a polymer layer. The polymer layer comprises a thrombin-cleavable peptide with a detectable moiety.

IPC Classes  ?

  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

92.

MICROFABRICATED DEVICE WITH MICRO-ENVIRONMENT SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES

      
Application Number US2015052333
Publication Number 2016/049515
Status In Force
Filing Date 2015-09-25
Publication Date 2016-03-31
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Di Tullio, Katrina Petronilla
  • Taylor, Jay Kendall
  • Zhao, Tian-Xian
  • Wong, Anjulia Chiu-Yuk
  • Martin, Glenn Brian
  • Thibodeau, Isabelle Louisette
  • Breeze, Steven Roy
  • Sutrala, Smitha Rk
  • Hong, Eric
  • Ball, Sheila Diane

Abstract

The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood

93.

CARTRIDGE DEVICE WITH FLUIDIC JUNCTIONS FOR COAGULATION ASSAYS IN FLUID SAMPLES

      
Application Number US2015052368
Publication Number 2016/049533
Status In Force
Filing Date 2015-09-25
Publication Date 2016-03-31
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Di Tullio, Katrina Petronilla
  • Taylor, Jay Kendall
  • Lee-Yow, Niko Daniel
  • Ball, Sheila Diane
  • Campbell, John Lewis Emerson

Abstract

The present invention relates to analytical testing devices comprising fluidic junctions and methods for assaying coagulation in a fluid sample received within the fluidic junctions. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a second reagent, a second sensor region, and a second fluidic lock valve. The sample analysis cartridge further includes a pump configured to push the first segment over the first sensor region to the first fluidic lock valve, and push the second segment over the second sensor region to the second fluidic lock valve.

IPC Classes  ?

  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood

94.

SINGLE CHANNEL CARTRIDGE DEVICE FOR COAGULATION ASSAYS IN FLUID SAMPLES

      
Application Number US2015052389
Publication Number 2016/049545
Status In Force
Filing Date 2015-09-25
Publication Date 2016-03-31
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Di Tullio, Katrina Petronilla
  • Taylor, Jay Kendall
  • Lee-Yow, Niko Daniel
  • Ball, Sheila Diane

Abstract

The present invention relates to analytical testing devices comprising a single channel with micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using a single channel with micro-environment sensors in a point of care test cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample and a conduit fluidically connected to the inlet chamber. The conduit includes a sensor chip including a first micro-environment sensor and a second microenvironment sensor, and a fluid lock valve. The sample analysis cartridge further includes a pump configured to push the biological sample over the first micro-environment sensor and the second microenvironment sensor to the fluidic lock valve such that the biological sample is positioned over the first micro-environment sensor and the second micro-environment sensor.

IPC Classes  ?

  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

95.

ELLAGIC ACID FORMULATIONS FOR USE IN COAGULATION ASSAYS

      
Application Number US2015052408
Publication Number 2016/049557
Status In Force
Filing Date 2015-09-25
Publication Date 2016-03-31
Owner ABBOTT POINT OF CARE INC. (USA)
Inventor
  • Collier, G. Bruce
  • Johns, Paul Willis, Jr.
  • Sutrala, Smitha Rk
  • Wang, Dan
  • Di Tullio, Katrina Petronilla

Abstract

The present invention relates to ellagic acid formulations for performing coagulation assays that are highly stable for long term storage and reduce assay time. Particularly, aspects of the present invention are directed to a composition and method of preparing ellagic acid in a highly soluble format for use in a coagulation assay. For example, the ellagic acid may be solubilized in one or more of sodium hydroxide, methanol, a polyether compound, particularly polyethylene glycol, polyethylene oxide, or polyoxyethylene, and a cyclodextrin guest-host complex.

IPC Classes  ?

  • G01N 33/86 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

96.

Methods and devices for determining sensing device usability

      
Application Number 14927508
Grant Number 09417201
Status In Force
Filing Date 2015-10-30
First Publication Date 2016-02-25
Grant Date 2016-08-16
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Martin, Glenn
  • Wang, Yi
  • Tonks, Simon
  • Feldman, Benjamin J.

Abstract

Methods and devices for determining sensing device usability, e.g., for self-monitoring and point of care devices. In one embodiment, the invention is to a method of determining device usability, comprising the steps of providing a device comprising a first electrical pad; a second electrical pad; and a humidity-responsive polymer layer contacting at least a portion of the first and second electrical pads; applying a potential across the first and second electrical pads; measuring an electrical property associated with the humidity-responsive polymer layer; and determining whether the measured electrical property associated with the humidity-responsive polymer layer has exceeded a humidity threshold level associated with the device usability.

IPC Classes  ?

  • G01N 27/04 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
  • G01R 35/00 - Testing or calibrating of apparatus covered by the other groups of this subclass

97.

Reader devices for optical and electrochemical test devices

      
Application Number 14919377
Grant Number 09488585
Status In Force
Filing Date 2015-10-21
First Publication Date 2016-02-11
Grant Date 2016-11-08
Owner Abbott Point of Care Inc. (USA)
Inventor
  • Emeric, Pierre
  • Davis, Graham
  • Ewart, Thomas
  • Gershtein, Sergey

Abstract

This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to devices having optical and electrochemical detectors and to methods of performing optical and electrochemical assays using such devices. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.

IPC Classes  ?

  • G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
  • G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator

98.

Biologic fluid sample analysis cartridge with non-reflective beads

      
Application Number 14768680
Grant Number 10895524
Status In Force
Filing Date 2014-02-19
First Publication Date 2016-01-07
Grant Date 2021-01-19
Owner Abbott Point of Care, Inc. (USA)
Inventor
  • Mehta, Manav
  • Holt, Robert

Abstract

A biological fluid sample analysis chamber and a method for analyzing a biological fluid sample is provided. The chamber includes a first chamber panel, a second chamber panel, and a plurality of beads disposed between the first chamber panel and the second chamber panel, which beads are configured to not reflect light incident to the beads in an amount that appreciably interferes with a photometric analysis of the biologic fluid.

IPC Classes  ?

  • G01N 1/28 - Preparing specimens for investigation
  • G01N 15/05 - Investigating sedimentation of particle suspensions in blood
  • B01L 9/00 - Supporting devices; Holding devices
  • G01N 21/03 - Cuvette constructions
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • G01N 21/64 - Fluorescence; Phosphorescence
  • G01N 21/59 - Transmissivity
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor

99.

I-STAT

      
Application Number 176085700
Status Registered
Filing Date 2015-12-22
Registration Date 2019-06-17
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments

Goods & Services

(1) Medical diagnostic reagents; blood analyzing testing reagents for medical diagnostic use; blood chemical analyzing diagnostic test strips for medical use; cartridges containing reagents for medical diagnostic use (2) Software and hardware related to blood, bodily fluid and tissue testing; software and hardware for configuring blood, bodily fluid and tissue testing systems; electronic data interfacing software and computer hardware for blood, bodily fluid and tissue testing systems; operating management software for medical diagnostic instruments and laboratory instruments; computer software and hardware for managing interface between medical diagnostic instruments and laboratory instruments; computer software and hardware for managing medical diagnostic laboratory workflow; laboratory information management software and hardware; computer software and hardware for monitoring medical diagnostic instruments and laboratory instruments; computer software and hardware for troubleshooting regarding medical diagnostic instruments and laboratory instruments; computer software for processing diagnostic medical testing data and laboratory data

100.

I-STAT

      
Application Number 014951362
Status Registered
Filing Date 2015-12-22
Registration Date 2016-04-27
Owner Abbott Point of Care Inc. (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments

Goods & Services

Medical diagnostic reagents; testing preparations for medical use; diagnostic tests for medical use; cartridges containing reagents for medical diagnostic use. Software and hardware related to blood, bodily fluid and tissue testing; software and hardware for configuring blood, bodily fluid and tissue testing systems; electronic data interfacing software and apparatus for blood, bodily fluid and tissue testing systems; computer hardware and software for use in the field of medical diagnostics; management software for medical diagnostic instruments and/or laboratory instruments; computer software and hardware for managing interface between medical diagnostic instruments and/or laboratory instruments; computer software and hardware for managing medical diagnostic laboratory workflow; laboratory information management software and hardware; computer software and hardware for monitoring medical diagnostic instruments and/or laboratory instruments; computer software and hardware for troubleshooting regarding medical diagnostic instruments and/or laboratory instruments; computer software for processing diagnostic medical testing data and/or laboratory data.
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