Abstract

A sensor chip (200) includes a measuring unit (41) and a measuring unit (42). The measuring unit (41) includes an electrode system (temperature electrodes) having a portion (31) of an electrode (11) and a portion (32) of an electrode (12), and a portion of a capillary (40) containing the portion (31) and the portion (32). The measuring unit (42) includes an electrode system (analysis electrodes) having a portion (33) of a sensor electrode (13) and a portion (34) of an electrode (14), and a portion of a capillary (40) containing the portion (33) and the portion (34) in addition to a reaction reagent layer (20). Data (a) related to the temperature of the blood sample is acquired based on the dimension of a current flowing through the temperature electrodes, and data (b) related to a concentration of an analyte in the blood sample is acquired based on the dimension of a current flowing through the analysis electrodes.

IPC Classes  ?

• G01N 27/416 - Systems
• G01N 27/327 - Biochemical electrodes

Abstract

A measuring device comprises a sensor holding part (10) for removably holding a sensor having an electrode terminal at its one end, a connection terminal (14) elastically brought into contact with the electrode terminal of the sensor to take out a signal necessary for analysis, an ejecting mechanism having a push-out member (11) which is so disposed as to be pushed out from the device body and adapted to eject the sensor held by the sensor holding part (10) in a state that the electrode terminal of the sensor is in elastic contact with the connection terminal (14) while disconnecting the electrode terminal of the sensor from the connection terminal (14) and pushing the sensor out, and ejecting the sensor from the sensor holding part (10), and a first brake part (13) which comes in elastic contact with the sensor when the sensor is pushed out by the ejection mechanism and brakes the movement of the sensor in the ejection direction. With this, the sensor can be ejected from the measuring device after the sample measurement without touching the sensor to which a sample is stuck, the operability is improved, and infective diseases are prevented.

IPC Classes  ?

• G01N 27/327 - Biochemical electrodes

Abstract

Provided is a biosensor measuring system capable of outputting a highly precise measurement result even either in the case of an impact such as a fall of a sensor or for an exposure sensor. The biosensor measuring system is enabled, by having an abnormal wave detecting electrode separately of a target substance determining electrode, to detect an impact, if any, due to the fall of the sensor even for a resting period having no voltage application in a voltage application algorithm. Moreover, the exposure sensor can also be detected with the abnormal waveform detected by the abnormal waveform detecting electrode.

IPC Classes  ?

• G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
• G01N 27/327 - Biochemical electrodes
• G01N 27/416 - Systems

Abstract

A liquid sample measurement apparatus of the present invention is provided with a timer (122) for measuring the time from when a biosensor (30) is attached to a liquid sample measurement device (110a) which measures the concentration of a specific component in a liquid sample that is applied to the biosensor (30) to when the liquid sample is applied to the biosensor (30), and correction based on the time measured by the timer (122) is performed to the measurement result of the concentration of the specific component in the liquid sample that is applied to the biosensor (30). Thereby, the measurement precision can be enhanced with utilizing the correction algorithm in which the ambient temperature and the temperature of the biosensor itself are considered.

IPC Classes  ?

• G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• C12Q 1/54 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
• G01N 27/416 - Systems
• G01N 33/483 - Physical analysis of biological material
• G01N 33/49 - Physical analysis of biological material of liquid biological material blood

Abstract

It is an object of the present invention to provide an excellent biosensor which can perform supply of a sample solution accurately and easily. A biosensor which has a capillary (7) for collecting a sample solution and analyzes a specific substance in the sample solution is provided with, in addition to an air hole (9), at least two supply ports, i.e., a sample supply port (13) and an auxiliary sample supply port (14), so that supply of the sample solution can be performed from either of the supply ports (13) and (14). Even when the sample supply port (13) is closed up with a fingertip or the like and supply of the sample solution is stopped, the sample solution can be quickly supplied from the other auxiliary sample supply port (14).

IPC Classes  ?

• G01N 27/327 - Biochemical electrodes

Abstract

A puncture device is constituted such that a plunger (2) is provided with a lever (3) which is partially restricted in rotation, and a forward urging force is obtained by a contraction restorative force of a tension spring (4), and the tension spring (4) is again expanded with the lever (3) as a leverage when the plunger (2) further moves forward due to its inertia from a position where no urging force is not applied, and the plunger (2) is urged backward by a restorative force of the re-expansion. Further, a puncture needle cartridge is provided with a lancet body (203) having a puncture needle, and a puncture needle holder (201) in which the lancet body (203) is movably stored, and further, the lancet body (203) has an arm means (302) and the puncture needle holder (201) contains a to-be-latched means (303) that cooperates with the arm means (302). Thereby, the fabrication process is simplified, and plural times of punctures of the puncture needle is prevented, and further, the puncture speed is controlled, and moreover, the used puncture needle is discarded safely.

IPC Classes  ?

• A61B 5/151 - Devices for taking samples of blood specially adapted for taking samples of capillary blood, e.g. by lancets
• A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles

Abstract

The present invention provides a method of measuring a component in blood, by which the amounts of blood cells and an interfering substance can be measured with high accuracy and high reliability and the amount of the component can be corrected accurately based on the amounts of the blood cells and the interfering substance. In a sensor for measuring a blood component, a first working electrode 13 measures a current that flows during a redox reaction of a blood component, a second working electrode 17 measures the amount of blood cells, and a third working electrode 12 measures the amount of an interfering substance. Next, based on the measurement results, the amount of the blood component to be measured is corrected. Thus, more accurate and precise measurement of the amount of the blood component can be realized.

IPC Classes  ?

• G01N 27/416 - Systems
• G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
• G01N 27/327 - Biochemical electrodes

Abstract

The present invention provides a method of electrochemically measuring a hematocrit (Hct) value using a sensor, capable of achieving excellent measurement accuracy and reliability and also provides a sensor used in the method. The method of electrochemically measuring a hematocrit (Hct) value of blood include: providing an electrode system having a working electrode (11) and. a counter electrode (12), in which a redox substance is provided on the counter electrode (12) but not on the working electrode (11); supplying blood to the electrode system, applying a voltage to the electrode system in this state to cause an oxidation current or a reduction current to flow between the working electrode (11) and the counter electrode (12); detecting the oxidation current or the reduction current and determining a Hct value based on a value of the detected current.

IPC Classes  ?

• G01N 27/416 - Systems
• G01N 27/327 - Biochemical electrodes
• G01N 33/49 - Physical analysis of biological material of liquid biological material blood

Abstract

A sensor for measuring a component in blood has a first analysis portion and a second analysis portion. The first analysis portion has a first electrode system (11,12) and a reagent layer (14), and the reagent layer (14) has an oxidoreductase that acts on the component and a mediator. In the first analysis portion, the component in the blood is measured by causing a redox reaction of the component with the oxidoreductase in the presence of the mediator and detecting a redox current caused when a voltage is applied by the first electrode (11,12). The second analysis portion has a working electrode and a counter electrode, and a mediator is provided on the counter electrode but not on the working electrode.

IPC Classes  ?

• G01N 27/416 - Systems
• G01N 27/327 - Biochemical electrodes
• G01N 33/49 - Physical analysis of biological material of liquid biological material blood