National Institute of Advanced Industrial Science and Technology

Japan

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IPC Class
H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers 3
A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups 2
A61P 35/00 - Antineoplastic agents 2
B01J 20/20 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes 2
B01J 20/28 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties 2
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Status
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Found results for  patents

1.

RADIATION SHIELDING JIG, METHOD FOR MANUFACTURING THE SAME, AND METHOD FOR USING THE SAME

      
Document Number 03216066
Status Pending
Filing Date 2023-10-11
Open to Public Date 2024-04-12
Owner
  • UNIVERSITY OF TSUKUBA (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • DAICO MFG CO., LTD. (Japan)
Inventor
  • Kumada, Hiroaki
  • Kitamura, Naoyuki
  • Nakamura, Tetsuyuki
  • Ikeda, Takeshi

Abstract

The purpose is to prevent the irradiation beam from leaking between the beam irradiation port of the radiation therapy device and the patient affected area that is the target of the emitted irradiation beam, a radiation shielding jig comprising a tare filled with shielding material particles; the tare is made of a resin fabric and has a hollow three-dimensional shape with a radiation pathway portion, the shielding material particles comprising a mixture of sintered particles having a predetermined particle diameter with radiation shielding performance and resin particles having a predetermined particle diameter.

2.

TARGET PROTEIN PRODUCTION METHOD

      
Document Number 03208968
Status Pending
Filing Date 2022-02-18
Open to Public Date 2022-08-25
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • ASAHI KASEI PHARMA CORPORATION (Japan)
Inventor
  • Yoshida, Keitaro
  • Yasutake, Yoshiaki
  • Tamura, Tomohiro
  • Konishi, Kenji
  • Sakasegawa, Shin-Ichi
  • Muramatsu, Shuji

Abstract

A method for producing a protein encoded by a target gene, comprising the step ofexpressing the target gene in a bacterium of the genus Burkholderia, wherein the bacterium lacks one or more genes selected from the group consisting of BSFP_068740, BSFP_068730, and BSFP_068720, or has inhibited expression of the genes or proteins encoded by the genes.

IPC Classes  ?

  • C12N 1/21 - Bacteria; Culture media therefor modified by introduction of foreign genetic material
  • C12N 9/16 - Hydrolases (3.) acting on ester bonds (3.1)
  • C12N 15/12 - Genes encoding animal proteins
  • C12N 15/55 - Hydrolases (3)
  • C12N 15/63 - Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

3.

ACTIVATED CARBON FOR ADSORBING NEURAL PER-AND POLYFLUOROALKYL COMPOUNDS AND ANALYSIS FOR NEUTRAL PER-AND POLYFLUOROALKYL COMPOUNDS IN WATER SAMPLE

      
Document Number 03188054
Status Pending
Filing Date 2021-09-24
Open to Public Date 2022-04-07
Owner
  • FUTAMURA KAGAKU KABUSHIKI KAISHA (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Yamashita, Nobuyoshi
  • Taniyasu, Sachi
  • Kousaka, Tsutomu
  • Yokoi, Makoto
  • Hori, Chiharu
  • Shimamura, Kodai
  • Asano, Takuya

Abstract

[Problem] The present invention provides a neutral per- and poly-fluoroalkyl compound adsorbing activated carbon that is used for an quantitative analysis of neutral per- and poly-fluoroalkyl compounds in a water sample, said activated carbon being capable of trapping neutral per- and poly-fluoroalkyl compounds in a releasable manner. [Solution] A neutral per- and poly-fluoroalkyl compound adsorbing activated carbon which is used for an quantitative analysis of neutral per- and poly-fluoroalkyl compounds in a water sample, and which is composed of an activated carbon having a BET specific surface area of 900 m2/g or more for the purpose of adsorbing neutral per- and poly-fluoroalkyl compounds that have been distributed in a gas phase from the water sample in a releasable manner by passing or bubbling an inert gas, which serves as a carrier gas, into the water sample that is sealed in a container and adjusted to a temperature at which the neutral per- and poly-fluoroalkyl compounds are able to be distributed in a gas phase.

IPC Classes  ?

  • G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups
  • C01B 32/306 - Active carbon with molecular sieve properties

4.

METHOD FOR SCREENING FOR POLYPEPTIDE THAT ACTS ON TARGET PROTEIN

      
Document Number 03190469
Status Pending
Filing Date 2021-08-04
Open to Public Date 2022-02-10
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor Kimura, Tadashi

Abstract

The present invention relates to a method for screening for a polypeptide that acts on a target protein. Specifically, the present invention relates to a method for screening for a polypeptide that acts on a target protein, the method comprising: (1) a step for providing a polynucleotide library constituted of a plurality of vectors that can be expressed by gram-negative bacteria, the plurality of vectors each including a first polynucleotide encoding mutually different polypeptide, a secretory signal sequence disposed upstream of the first polynucleotide, and a second polynucleotide encoding the target protein; (2) a step for transforming gram-negative bacteria with the expression vector, expressing the polypeptide inside the periplasm space, and expressing the target protein on the surface of the internal membrane; (3) a step for bringing the polypeptide into contact with the target protein within the periplasm space; (4) a step for allowing the gram-negative bacterial to form spheroplast and measuring the activity of the polypeptide on the target protein in an electrochemical manner; and (5) a step for identifying, on the basis of the measured activity, a polypeptide that acts on the target protein.

IPC Classes  ?

  • C12P 21/00 - Preparation of peptides or proteins
  • C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
  • C40B 40/08 - Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
  • C40B 40/10 - Libraries containing peptides or polypeptides, or derivatives thereof
  • G01N 33/15 - Medicinal preparations

5.

NOVEL COMPOUND USEFUL AS TOLL-LIKE RECEPTOR 7 ACTIVATION INHIBITOR

      
Document Number 03181905
Status Pending
Filing Date 2021-06-07
Open to Public Date 2021-12-16
Owner
  • TOYAMA PREFECTURAL UNIVERSITY (Japan)
  • TEIKA PHARMACEUTICAL CO., LTD. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Nagai, Yoshinori
  • Okamoto, Naoki
  • Fujishita, Shigeto
  • Hirokawa, Takatsugu

Abstract

CB-7 exhibits a weak TLR7 inhibiting effect in normal mice. The present invention provides a novel compound with a stronger TLR7 inhibiting effect than CB-7, a pharmaceutically acceptable salt of said compound, or a prodrug of said compound or salt. The present invention also provides a drug for the prevention or treatment of diseases associated with the activation of TLR7, said drug including the aforementioned TLR7 activation inhibitor.

IPC Classes  ?

  • C07C 43/178 - Unsaturated ethers containing hydroxy or O-metal groups
  • A61K 31/08 - Ethers or acetals acyclic, e.g. paraformaldehyde
  • A61K 31/085 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
  • A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
  • A61K 31/216 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
  • A61P 1/02 - Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
  • A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
  • A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
  • A61P 1/18 - Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
  • A61P 3/04 - Anorexiants; Antiobesity agents
  • A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
  • A61P 7/06 - Antianaemics
  • A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
  • A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
  • A61P 17/06 - Antipsoriatics
  • A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
  • A61P 21/04 - Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
  • A61P 31/04 - Antibacterial agents
  • A61P 31/18 - Antivirals for RNA viruses for HIV
  • A61P 37/02 - Immunomodulators
  • A61P 37/06 - Immunosuppressants, e.g. drugs for graft rejection
  • C07C 215/30 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
  • C07D 205/04 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
  • C07D 211/38 - Halogen atoms or nitro radicals
  • C07D 295/096 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
  • C07D 295/185 - Radicals derived from carboxylic acids from aliphatic carboxylic acids
  • C07D 307/94 - Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins

6.

METHOD FOR PRODUCING NOVEL MICROORGANISMS AND ERGOTHIONEINE

      
Document Number 03163427
Status In Force
Filing Date 2020-08-06
Open to Public Date 2021-07-15
Grant Date 2023-02-28
Owner
  • KUREHA CORPORATION (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Koshiyama, Tatsuyuki
  • Kaneko, Mutsumi
  • Higashiyama, Yukihiro
  • Sato, Shun
  • Morita, Tomotake
  • Saika, Azusa

Abstract

Microorganisms according to the present invention are Dirkmeia churashimaensis (NITE BP-03054), Papiliotrema flavescens (NITE BP-03051), Papiliotrema flavescens (NITE BP-03052), or Apiotrichum porosum (NITE BP-03053).

IPC Classes  ?

7.

PER- AND POLYFLUOROALKYL COMPOUND-ADSORBING ACTIVATED CARBON

      
Document Number 03148503
Status Pending
Filing Date 2020-08-11
Open to Public Date 2021-02-25
Owner
  • FUTAMURA KAGAKU KABUSHIKI KAISHA (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Yamashita, Nobuyoshi
  • Taniyasu, Sachi
  • Kousaka, Tsutomu
  • Yokoi, Makoto
  • Hori, Chiharu
  • Shimamura, Kodai
  • Asano, Takuya

Abstract

[OBJECT] To provide a per- and polyfluoroalkyl compound-adsorbing activated carbon having a high collection rate of per- and polyfluoroalkyl compounds in an atmospheric sample, and a filter body using the same.[ACHIEVING MEANS] A per- and polyfluoroalkyl compound-adsorbing activated carbon for desorbably adsorbing per- and polyfluoroalkyl compounds in an atmospheric sample, the activatedcarbon including an activated carbon adsorbent having a BET specific surface area of 900 m2/g or more, a sum (Vmic) of a volume of micropores of 1 nm or less of 0.35 cm3/g or more, a sum (Vmet)of a volume of mesopores of 2 to 60 nm of 0.02 cm3/g or more, a volume difference (Vs) betweenthe micropore volume (Vmic) and the mesopore volume (Vmet) of 0.45 or more, and a surface oxide amount of 0.10 meq/g or more.

IPC Classes  ?

  • B01J 20/20 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
  • C01B 32/30 - Active carbon
  • B01J 20/28 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties

8.

ACTIVATED CARBON FOR ADSORBING PER-AND POLYFLUOROALKYL COMPOUNDS IN WATER SAMPLE

      
Document Number 03148636
Status Pending
Filing Date 2020-08-11
Open to Public Date 2021-02-25
Owner
  • FUTAMURA KAGAKU KABUSHIKI KAISHA (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Yamashita, Nobuyoshi
  • Taniyasu, Sachi
  • Kousaka, Tsutomu
  • Yokoi, Makoto
  • Hori, Chiharu
  • Shimamura, Kodai
  • Asano, Takuya

Abstract

[OBJECT] To provide an activated carbon for adsorbing per- and polyfluoroalkyl compounds in a water sample, the activated carbon having a high collection rate of per- and polyfluoroalkyl compounds in a water sample, and a filter body using the same.[ACHIEVING MEANS] An activated carbon for adsorbing per- and polyfluoroalkyl compounds in a water sample to desorbably adsorb per- and polyfluoroalkyl compounds in a water sample, wherein the activated carbon is composed of an activated carbon adsorbent having a BET specificsurface area of 800 m2/g or more or a surface oxide amount of 0.20 meq/g or less, or alternatively, a BET specific surface area of 800 m2/g or more and a surface oxide amount of 0.50 meq/g or less,and wherein a sum (Vmic) of a volume of micropores of 1 nm or less of the activated carbonadsorbent is 0.30 cm3/g or more.

IPC Classes  ?

  • B01J 20/20 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising carbon obtained by carbonising processes
  • C01B 32/30 - Active carbon
  • B01J 20/28 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
  • C02F 1/28 - Treatment of water, waste water, or sewage by sorption

9.

SODIUM BOROHYDRIDE PRODUCTION METHOD

      
Document Number 03149798
Status In Force
Filing Date 2020-08-05
Open to Public Date 2021-02-11
Grant Date 2023-06-27
Owner
  • NIPPON LIGHT METAL COMPANY, LTD. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Sugita, Kaoru
  • Oota, Yuji
  • Abe, Rene Yo
  • Hachisu, Takuma
  • Matsunaga, Takehiro

Abstract

This sodium borohydride is produced, in a closed container filled with hydrogen gas, by mixing sodium borates, aluminum powder and fluoride powder, and performing a reaction at 410°C-560°C.

IPC Classes  ?

  • C01B 6/21 - Preparation of borohydrides of alkali metals, alkaline earth metals, magnesium or beryllium; Addition complexes thereof, e.g. LiBH4.2N2H4, NaB2H7
  • C01B 3/00 - Hydrogen; Gaseous mixtures containing hydrogen; Separation of hydrogen from mixtures containing it; Purification of hydrogen

10.

SODIUM BOROHYDRIDE PRODUCTION METHOD

      
Document Number 03149799
Status Pending
Filing Date 2020-08-05
Open to Public Date 2021-02-11
Owner
  • NIPPON LIGHT METAL COMPANY, LTD. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Sugita, Kaoru
  • Oota, Yuji
  • Abe, Rene Yo
  • Hachisu, Takuma
  • Matsunaga, Takehiro

Abstract

Provided is a method for producing sodium borohydride, in which a sodium borate and aluminum powder are reacted at 400°C to 560°C while being stirred in a sealed container filled with hydrogen gas, such that the molar ratio of sodium contained in the sodium borate to boron contained in the sodium borate exceeds 0.5.

IPC Classes  ?

  • C01B 6/21 - Preparation of borohydrides of alkali metals, alkaline earth metals, magnesium or beryllium; Addition complexes thereof, e.g. LiBH4.2N2H4, NaB2H7
  • C01B 3/00 - Hydrogen; Gaseous mixtures containing hydrogen; Separation of hydrogen from mixtures containing it; Purification of hydrogen
  • C01B 6/15 - Metal borohydrides; Addition complexes thereof

11.

METHOD FOR PRODUCING ALL-SOLID-STATE BATTERY

      
Document Number 03132801
Status Pending
Filing Date 2020-03-04
Open to Public Date 2020-09-17
Owner
  • MITSUBISHI GAS CHEMICAL COMPANY, INC. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Nogami, Genki
  • Noguchi, Keita
  • Katori, Aki
  • Yamashita, Naoto
  • Mukai, Takashi
  • Yanagida, Masahiro

Abstract

The present invention is able to provide a method for producing an all-solid-state battery that has a solid electrolyte layer between a positive electrode layer and a negative electrode layer. This method for producing an all-solid-state battery is characterized by comprising: a step wherein a coating liquid is applied to at least one of the positive electrode layer and the negative electrode layer, said coating liquid containing a solid electrolyte solution, which is obtained by dissolving a solid electrolyte in a solvent, and fine particles which are insoluble in the solid electrolyte solution; and a step wherein the solvent is removed from the applied coating liquid, thereby having the solid electrolyte deposit on at least one of the positive electrode layer and the negative electrode layer.

IPC Classes  ?

  • H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulators; Processes of manufacture thereof
  • H01M 10/052 - Li-accumulators
  • H01M 10/0562 - Solid materials
  • H01M 10/0585 - Construction or manufacture of accumulators having only flat construction elements, i.e. flat positive electrodes, flat negative electrodes and flat separators

12.

OPTICALLY HEAT-GENERATING COMPOSITE MATERIAL, NANOCLUSTER, SUBSTANCE DELIVERY CARRIER AND PHARMACEUTICAL COMPOSITION

      
Document Number 03133192
Status Pending
Filing Date 2020-03-03
Open to Public Date 2020-09-17
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • DAICEL CORPORATION (Japan)
Inventor
  • Miyako, Eijiro
  • Yu, Yue
  • Nishikawa, Masahiro
  • Liu, Ming
  • Tei, Takahiro

Abstract

The present invention provides an optically heat-generating composite material which is represented by formula (I) CNM-(Y1-R)n1 (wherein CNM represents a carbon nanomaterial; Y1 represents a divalent linking group; R represents a group derived from a fluorescent substance or a pigment; and n1 represents an integer of 1 or more).

IPC Classes  ?

  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 47/52 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
  • C01B 32/15 - Nanosized carbon materials
  • C01B 32/28 - After-treatment, e.g. purification, irradiation, separation or recovery
  • A61K 33/44 - Elemental carbon, e.g. charcoal, carbon black
  • A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
  • A61P 35/00 - Antineoplastic agents
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups

13.

MODIFIED CARBON NANOMATERIAL, NANOCLUSTER, SUBSTANCE DELIVERY CARRIER AND PHARMACEUTICAL COMPOSITION

      
Document Number 03132504
Status Pending
Filing Date 2020-03-03
Open to Public Date 2020-09-17
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • DAICEL CORPORATION (Japan)
Inventor
  • Miyako, Eijiro
  • Yu, Yue
  • Nishikawa, Masahiro
  • Liu, Ming
  • Tei, Takahiro

Abstract

The present invention provides a nanocluster which is composed of self-assembled carbon nanomaterials that are modified with higher alkyl groups or higher alkenyl groups.

IPC Classes  ?

  • A61K 47/04 - Non-metals; Compounds thereof
  • B82Y 5/00 - Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
  • B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
  • B82Y 40/00 - Manufacture or treatment of nanostructures
  • A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
  • C01B 32/15 - Nanosized carbon materials
  • A61K 9/14 - Particulate form, e.g. powders

14.

THERMOELECTRIC ELEMENT, THERMOELECTRIC DEVICE AND METHOD FOR FORMING THERMOELECTRIC ELEMENT

      
Document Number 03091726
Status Pending
Filing Date 2019-02-18
Open to Public Date 2019-09-06
Owner
  • GCE INSTITUTE INC. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Goto, Hiroshi
  • Sakata, Minoru
  • Maeda, Ryutaro
  • Lu, Jian

Abstract

[Problem] To provide: a thermoelectric element which can be easily formed and with which stable characteristics can be obtained; a thermoelectric device; and a method for manufacturing the thermoelectric element. [Solution] A thermoelectric element 10 that converts thermal energy to electrical energy is characterized by comprising: a first electrode 3; a second electrode 4 that has a work function different from the first electrode 3 and that is disposed so as to be separated from the first electrode 3 on the same plane of a first substrate 1; and an intermediate part 5 that is provided between the first electrode 3 and the second electrode 4 and that includes nanoparticles.

IPC Classes  ?

  • B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
  • H02N 11/00 - Generators or motors not provided for elsewhere; Alleged perpetua mobilia obtained by electric or magnetic means

15.

PRODUCTION METHOD FOR ALL-SOLID-STATE BATTERY

      
Document Number 03079165
Status Pending
Filing Date 2018-10-12
Open to Public Date 2019-04-25
Owner
  • MITSUBISHI GAS CHEMICAL COMPANY, INC. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Nogami, Genki
  • Shimada, Masahiro
  • Ito, Tomohiro
  • Katori, Aki
  • Noguchi, Keita
  • Yamashita, Naoto
  • Mukai, Takashi
  • Yanagida, Masahiro

Abstract

The present invention makes it possible to provide a production method for an all-solid-state battery having a solid electrolyte layer between a positive electrode layer and a negative electrode layer, the production method being characterized by including: a step for coating or impregnating the positive electrode layer and/or the negative electrode layer with a solid electrolyte solution in which a boron hydride compound serving as the solid electrolyte has been dissolved in a solvent; and a step for removing the solvent from the coated or impregnated solid electrolyte solution and causing the solid electrolyte to precipitate on the positive electrode layer and/or the negative electrode layer.

IPC Classes  ?

  • H01M 10/0562 - Solid materials
  • H01M 4/139 - Processes of manufacture
  • H01M 4/1395 - Processes of manufacture of electrodes based on metals, Si or alloys
  • H01M 10/0585 - Construction or manufacture of accumulators having only flat construction elements, i.e. flat positive electrodes, flat negative electrodes and flat separators
  • H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
  • H01M 4/48 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides
  • H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers

16.

MALIGNANT TUMOR TARGET PEPTIDE

      
Document Number 03032775
Status In Force
Filing Date 2017-08-16
Open to Public Date 2018-02-22
Grant Date 2024-01-23
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Fukuda, Michiko
  • Nonaka, Motohiro

Abstract

The present invention provides a peptide comprising an amino acid sequence represented by any of formulas (I)-(III), and a conjugate comprising the peptide and a functional part. (I) The amino acid sequence (X1) [D]P[D](X2)[D] (in the sequence, X1 represents W or F, X2 represents S or T, and each amino acid symbol directly followed by the symbol [D] represents the D form of said amino acid) (II) The amino acid sequence P[D]T[D](X)nF[D] (in the sequence, (X)n represents n given amino acids selected independently, n represents an integer of 0-4, and the symbol [D] represents the same as above) (III) a retro-inverso amino acid sequence of any of the amino acid sequences among (I) and (II).

IPC Classes  ?

  • C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
  • A61K 38/03 - Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 49/04 - X-ray contrast preparations
  • A61K 49/06 - Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations
  • A61K 49/14 - Peptides, e.g. proteins
  • A61P 35/00 - Antineoplastic agents
  • C07K 14/00 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
  • C07K 19/00 - Hybrid peptides
  • C12N 15/09 - Recombinant DNA-technology

17.

ORGANIC-INORGANIC COMPOSITE LAYERED STRUCTURE HAVING HIGH ADHESIVE PROPERTIES, AND HIGH HARDNESS OR EXCELLENT TRANSPARENCY

      
Document Number 03024463
Status In Force
Filing Date 2017-05-16
Open to Public Date 2017-11-23
Grant Date 2021-08-10
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Akedo, Jun
  • Noda, Hiroaki
  • Tsuda, Hiroki
  • Sakamoto, Nobuo

Abstract

According to the present invention, a multilayer structure having high hardness or excellent transparency is produced, with high adhesion characteristics, on a base such as a resin. A multilayer structure which is provided with: an organic-inorganic hybrid member which is configured of primary inorganic particles and an organic polymer covalently bonded to each other so that the primary inorganic particles constitute a network that contains the polymer; and a particle assembly layer which is deposited on the organic-inorganic hybrid member and is configured of secondary particles that are formed of an inorganic material or a metal material. The primary inorganic particles of the organic-inorganic hybrid member and the secondary particles have different crystal grain sizes.

IPC Classes  ?

  • B32B 9/00 - Layered products essentially comprising a particular substance not covered by groups
  • B32B 27/18 - Layered products essentially comprising synthetic resin characterised by the use of special additives

18.

METHOD FOR SEPARATING METAL COMPONENTS

      
Document Number 03010721
Status In Force
Filing Date 2016-12-27
Open to Public Date 2017-07-13
Grant Date 2023-10-03
Owner
  • SUMITOMO ELECTRIC INDUSTRIES, LTD. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Awazu, Tomoyuki
  • Majima, Masatoshi
  • Tsubokura, Mitsutaka
  • Oishi, Tetsuo

Abstract

A method for separating metal components from a treatment material containing a silicate and metal elements includes: a reaction step of reacting the treatment material and a molten alkali hydroxide in which bubbles due to water vapor derived from water are generated by heating a hydroxide of an alkali metal or an alkaline-earth metal and the water in a state where the hydroxide and the water coexist, to obtain a reaction product; and a first precipitation step of dissolving the reaction product of the treatment material and the molten alkali hydroxide after the reaction step in water, thereby generating a precipitate containing the metal elements.

IPC Classes  ?

  • C22B 59/00 - Obtaining rare earth metals
  • C22B 3/06 - Extraction of metal compounds from ores or concentrates by wet processes by leaching in inorganic acid solutions
  • C22B 3/12 - Extraction of metal compounds from ores or concentrates by wet processes by leaching in inorganic alkaline solutions
  • C22B 3/26 - Treatment or purification of solutions, e.g. obtained by leaching by liquid-liquid extraction using organic compounds
  • C22B 3/42 - Treatment or purification of solutions, e.g. obtained by leaching by ion-exchange extraction
  • C22B 34/14 - Obtaining zirconium or hafnium
  • C22B 47/00 - Obtaining manganese
  • C25C 3/26 - Electrolytic production, recovery or refining of metals by electrolysis of melts of titanium, zirconium, hafnium, tantalum or vanadium
  • C25C 3/30 - Electrolytic production, recovery or refining of metals by electrolysis of melts of manganese
  • C25C 3/34 - Electrolytic production, recovery or refining of metals by electrolysis of melts of metals not provided for in groups

19.

METHOD OF MANUFACTURING SOFT MAGNETIC DUST CORE AND SOFT MAGNETIC DUST CORE

      
Document Number 02990362
Status In Force
Filing Date 2016-07-28
Open to Public Date 2017-02-09
Grant Date 2020-03-10
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • JFE STEEL CORPORATION (Japan)
Inventor
  • Nakamura, Naomichi
  • Nakaseko, Makoto
  • Takashita, Takuya
  • Muraki, Mineo
  • Terao, Hoshiaki
  • Wada, Raita
  • Urata, Akiri
  • Kanamori, Yu
  • Yamaki, Makoto
  • Okamoto, Koichi
  • Tsuda, Toshinori
  • Sato, Shoichi
  • Ozaki, Kimihiro

Abstract

Provided is a soft magnetic dust core having high density and favorable properties. A method of manufacturing a soft magnetic dust core includes: preparing coated powder including amorphous powder made of an Fe-B-Si-P-C-Cu-based alloy, an Fe-B-P-C-Cu-based alloy, an Fe-B-Si-P-Cu-based alloy, or an Fe-B-P-Cu-based alloy, with a first initial crystallization temperature Tx1 and a second initial crystallization temperature Tx2; and a coating formed on a surface of particles of the amorphous powder; applying a compacting pressure to the coated powder or a mixture of the coated powder and the amorphous powder at a temperature equal to or lower than Tx1 ¨ 100 K; and heating to a maximum end-point temperature equal to or higher than Tx1 ¨ 50 K and lower than Tx2 with the compacting pressure being applied.

IPC Classes  ?

  • H01F 41/02 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformers; Apparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for manufacturing cores, coils or magnets
  • B22F 3/02 - Compacting only
  • C22C 38/00 - Ferrous alloys, e.g. steel alloys
  • C22C 45/02 - Amorphous alloys with iron as the major constituent
  • H01F 1/153 - Amorphous metallic alloys, e.g. glassy metals
  • H01F 1/22 - Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials metals or alloys in the form of particles, e.g. powder pressed, sintered, or bound together
  • H01F 27/255 - Magnetic cores made from particles

20.

PARTIAL DISCHARGE-RESISTANT ELECTRICAL INSULATING RESIN COMPOSITION

      
Document Number 02991696
Status In Force
Filing Date 2016-07-07
Open to Public Date 2017-01-12
Grant Date 2023-09-12
Owner
  • SUMITOMO SEIKA CHEMICALS CO., LTD. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • SHIZUOKA INSTITUTE OF SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Hayashizaka, Noriyuki
  • Kawasaki, Kazunori
  • Yamashita, Masayuki
  • Ebina, Takeo
  • Ishida, Takahiro
  • Hattori, Satomi

Abstract

The present invention addresses the problem of providing an excellent electrical insulating resin composition for partial-discharge resistance with which it is possible to inhibit the deterioration of an insulator resulting from partial discharge. This electrical insulating resin composition for partial-discharge resistance contains Boehmite alumina and a resin.

IPC Classes  ?

  • H01B 3/30 - Insulators or insulating bodies characterised by the insulating materials; Selection of materials for their insulating or dielectric properties mainly consisting of organic substances waxes
  • C08K 3/22 - Oxides; Hydroxides of metals
  • C08L 101/00 - Compositions of unspecified macromolecular compounds
  • H01B 3/00 - Insulators or insulating bodies characterised by the insulating materials; Selection of materials for their insulating or dielectric properties
  • H01B 7/02 - Disposition of insulation

21.

GENE EXPRESSION SYSTEM USING STEALTHY RNA, AND GENE INTRODUCTION/EXPRESSION VECTOR INCLUDING SAID RNA

      
Document Number 02973943
Status Pending
Filing Date 2016-01-18
Open to Public Date 2016-07-21
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • TOKIWA-BIO INC. (Japan)
Inventor
  • Nakanishi, Mahito
  • Iijima, Minoru

Abstract

The present invention enables simultaneous and stable expression of a plurality of foreign genes by using a stealthy RNA gene expression system that is a complex that does not activate the innate immune mechanism and is formed from an RNA-dependent RNA polymerase, a single-strand RNA binding protein, and negative-sense single-strand RNAs including the following (1) to (8): (1) a target RNA sequence that codes for any protein or functional RNA; (2) an RNA sequence forming a noncoding region and derived from mRNA expressed in animal cells; (3) a transcription initiation signal sequence recognized by the RNA-dependent RNA polymerase; (4) a transcription termination signal sequence recognized by the polymerase; (5) an RNA sequence containing a replication origin recognized by the polymerase; (6) an RNA sequence that codes for the polymerase and of which codons are optimized for the species from which an introduction target cell is derived; (7) an RNA sequence that codes for a protein for regulating the activity of the polymerase and of which codons are optimized for the species from which the introduction target cell is derived; and (8) an RNA sequence that codes for the single-strand RNA binding protein and of which codons are optimized for the species from which the introduction target cell is derived.

IPC Classes  ?

  • C12N 15/09 - Recombinant DNA-technology
  • C12N 5/14 - Plant cells
  • C12N 7/00 - Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof

22.

ELECTROCHEMICAL ELEMENT, SOLID OXIDE FUEL CELL, AND METHODS FOR PRODUCING THE SAME

      
Document Number 02961710
Status In Force
Filing Date 2015-09-18
Open to Public Date 2016-03-24
Grant Date 2023-03-14
Owner
  • OSAKA GAS CO., LTD. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Echigo, Mitsuaki
  • Ohnishi, Hisao
  • Manabe, Kyohei
  • Yamazaki, Osamu
  • Minami, Kazuyuki
  • Akedo, Jun
  • Suzuki, Toshio

Abstract

This invention achieves an electrochemical element and a cell for a solid oxide fuel cell of high capabilities, and preparation methods for these, wherein the contact between a dense and highly hermetic electrolyte layer and an electrode layer has been improved, while the processing temperature during the electrolyte layer formation is kept low. The electrochemical element has an electrode layer (3), and an electrolyte layer (4) layered onto the electrode layer (3). The electrode layer (3) has a plurality of pores that are open on the surface in contact with the electrolyte layer (4). The pores are filled with microparticles comprising the same constituents as the electrolyte layer (4).

IPC Classes  ?

  • H01M 8/1246 - Fuel cells with solid electrolytes operating at high temperature, e.g. with stabilised ZrO2 electrolyte characterised by the process of manufacturing or by the material of the electrolyte the electrolyte consisting of oxides
  • H01M 8/1097 - Fuel cells applied on a support, e.g. miniature fuel cells deposited on silica supports
  • C25B 11/031 - Porous electrodes
  • C25B 13/07 - Diaphragms; Spacing elements characterised by the material based on inorganic materials based on ceramics
  • C25B 1/04 - Hydrogen or oxygen by electrolysis of water
  • H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells

23.

NEGATIVE ELECTRODE MIXTURE FOR NON-AQUEOUS ELECTROLYTE SECONDARY CELL AND ITS USE

      
Document Number 02916160
Status In Force
Filing Date 2014-03-19
Open to Public Date 2014-12-31
Grant Date 2021-04-20
Owner
  • SUMITOMO SEIKA CHEMICALS CO., LTD. (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Kinpara, Yuji
  • Fujishige, Junichi
  • Fujimoto, Nobutaka
  • Mukai, Takashi
  • Morishita, Masanori
  • Sakai, Tetsuo

Abstract

This negative-electrode mixture for a non-aqueous electrolyte secondary cell contains a negative-electrode active material, a conductive auxiliary agent, and a binder, the binder containing a copolymer of vinyl alcohol and an alkali-metal-neutralized ethylenically unsaturated carboxylic acid.

IPC Classes  ?

  • H01M 4/134 - Electrodes based on metals, Si or alloys
  • H01M 4/133 - Electrodes based on carbonaceous material, e.g. graphite-intercalation compounds or CFx
  • H01M 4/587 - Carbonaceous material, e.g. graphite-intercalation compounds or CFx for inserting or intercalating light metals
  • H01M 4/36 - Selection of substances as active materials, active masses, active liquids
  • H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers

24.

ADSORBENT FOR RARE EARTH ELEMENT AND METHOD FOR RECOVERING RARE EARTH ELEMENT

      
Document Number 02907925
Status In Force
Filing Date 2014-03-25
Open to Public Date 2014-10-02
Grant Date 2017-12-05
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Ogata, Takeshi
  • Tanaka, Mikiya

Abstract

The present invention provides an adsorbent for rare earth element and a method for recovering a rare earth element. It provides an adsorbent for rare earth element which is located in an aqueous phase and brought into contact with an aqueous solution containing a rare earth element to adsorb and recover the rare earth element, the adsorbent comprising a base material and diglycolamic acid introduced into the base material. Further, the present invention provides a method for recovering a rare earth element comprising: bringing an aqueous solution containing a rare earth element into contact with the adsorbent for rare earth element to allow the rare earth element to be adsorbed on the adsorbent for rare earth element; and desorbing the rare earth element adsorbed on the adsorbent for rare earth element with an acid of 1 N or less.

IPC Classes  ?

  • B01J 20/22 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
  • B01J 20/30 - Processes for preparing, regenerating or reactivating
  • B01J 20/34 - Regenerating or reactivating
  • C02F 1/28 - Treatment of water, waste water, or sewage by sorption
  • C22B 3/24 - Treatment or purification of solutions, e.g. obtained by leaching by physical processes, e.g. by filtration, by magnetic means by adsorption on solid substances, e.g. by extraction with solid resins
  • C22B 59/00 - Obtaining rare earth metals
  • C07C 235/06 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
  • C22B 7/00 - Working-up raw materials other than ores, e.g. scrap, to produce non-ferrous metals or compounds thereof

25.

A LITHIUM ION SECONDARY BATTERY COMPRISING A RANDOM COPOLYMER BINDER IN THE POSITIVE ELECTRODE THEREOF

      
Document Number 02886569
Status In Force
Filing Date 2013-10-01
Open to Public Date 2014-04-17
Grant Date 2021-03-30
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • SUMITOMO SEIKA CHEMICALS CO., LTD. (Japan)
Inventor
  • Mukai, Takashi
  • Morishita, Masanori
  • Sakai, Tetsuo
  • Kinpara, Yuji
  • Fujishige, Junichi
  • Fujimoto, Nobutaka
  • Karashima, Shuichi

Abstract

This binder for use in a positive electrode for a lithium ion secondary battery contains a copolymer of both vinyl alcohol and an alkali-metal-neutralized ethylenically unsaturated carboxylic acid.

IPC Classes  ?

  • H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
  • H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulators; Processes of manufacture thereof
  • H01M 4/36 - Selection of substances as active materials, active masses, active liquids

26.

CIRCADIAN RHYTHM-IMPROVING AGENT

      
Document Number 02865874
Status In Force
Filing Date 2013-02-08
Open to Public Date 2013-09-06
Grant Date 2020-06-09
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • SAPPORO BREWERIES LIMITED (Japan)
Inventor
  • Ooishi, Katsutaka
  • Miyazaki, Koyomi
  • Itoh, Nanako
  • Yamamoto, Saori
  • Nakakita, Yasukazu
  • Kaneda, Hirotaka

Abstract

The present invention provides a circadian rhythm-improving agent containing lactic acid bacteria or a processed product thereof as an active ingredient.

IPC Classes  ?

  • A61K 35/744 - Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
  • A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A23L 2/52 - Adding ingredients
  • A61P 25/00 - Drugs for disorders of the nervous system
  • A61P 25/20 - Hypnotics; Sedatives
  • C12N 1/20 - Bacteria; Culture media therefor

27.

METHOD OF MOLDING GAS HYDRATE PELLET

      
Document Number 02834763
Status In Force
Filing Date 2012-03-19
Open to Public Date 2012-10-04
Grant Date 2019-09-24
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Iwabuchi, Wataru
  • Egami, Tomoaki
  • Narita, Hideo
  • Nagao, Jiro
  • Suzuki, Kiyofumi

Abstract

[Problem] To provide a method of molding a gas hydrate pellet for improving convenience of handling of a natural gas hydrate during transportation and storage, and thereby improving the practical use of the natural gas hydrate. [Solution] Gas hydrate slurry is fed in a compression chamber 21, and pressure and compression are applied to the gas hydrate slurry by advancing a compression plunger 21e. At that time, a stroking speed of the compression plunger 21e is set minimum, preferably less than a value expressed by a stroke length of the compression plunger 21e at compression x 10-2 (m/min). By advancing the compression plunger 21e at low speed, binding between particles of the gas hydrate is tightened, thereby the gas hydrate pellet with increased shearing strength can be molded.

IPC Classes  ?

  • C10L 3/06 - Natural gas; Synthetic natural gas obtained by processes not covered by , or
  • B01J 2/22 - Processes or devices for granulating materials, in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by pressing in moulds or between rollers
  • B30B 9/04 - Presses specially adapted for particular purposes for squeezing-out liquid from liquid-containing material, e.g. juice from fruits, oil from oil-containing material using press rams

28.

METHOD OF EFFICIENTLY ESTABLISHING INDUCED PLURIPOTENT STEM CELLS

      
Document Number 02789749
Status In Force
Filing Date 2011-02-16
Open to Public Date 2011-08-25
Grant Date 2018-09-04
Owner
  • KYOTO UNIVERSITY (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • JAPAN BIOLOGICAL INFORMATICS CONSORTIUM (Japan)
Inventor
  • Yamanaka, Shinya
  • Goshima, Naoki
  • Maekawa, Momoko
  • Kawamura, Yoshifumi
  • Mochizuki, Hiromi

Abstract

Provided are a method of improving the efficiency of establishment of iPS cells, comprising the step of contacting one or more substances selected from the group consisting of members of the GLIS family (e.g., GLIS1) and nucleic acids that encode the same and one or more substances selected from the group consisting of members of the Klf family and nucleic acids that encode the same, with a somatic cell, an iPS cell comprising an exogenous nucleic acid that encodes a member of the GLIS family or a member of the Klf family, that can be obtained by the method, and a method of producing a somatic cell by inducing the differentiation of the iPS cell.

IPC Classes  ?

  • C12N 5/0735 - Embryonic stem cells; Embryonic germ cells

29.

METHOD FOR PRODUCING THERMOELECTRIC MODULE

      
Document Number 02754081
Status In Force
Filing Date 2010-03-01
Open to Public Date 2010-09-16
Grant Date 2016-11-01
Owner
  • KABUSHIKI KAISHA ATSUMITEC (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Uchiyama, Naoki
  • Kubo, Kazuya
  • Mikami, Masashi
  • Kobayashi, Keizo
  • Nishio, Toshiyuki

Abstract

A method of producing a thermoelectric conversion device, provided with: a step of disposing electrodes (4) respectively to opposing surfaces of a pair of current-pressure applying members (2) which face each other; a step of interposing a plurality of members of thermoelectric conversion material (3) between the electrodes (4); and a step of bonding the electrodes (4) to the thermoelectric conversion material (3) by applying pressure to the electrodes (4) and thermoelectric conversion material (3) with the current-pressure applying member (2) while applying current to the electrodes (4) and the thermoelectric conversion material (3). The method of producing a thermoelectric conversion device is further provided with a step of forming intermediate layers (5), which include conductive metal powder and have plasticity, between the electrodes (4) and the thermoelectric conversion material (3).

IPC Classes  ?

  • H02N 11/00 - Generators or motors not provided for elsewhere; Alleged perpetua mobilia obtained by electric or magnetic means

30.

NUCLEAR REPROGRAMMING SUBSTANCE COMPRISING GLIS1

      
Document Number 02753845
Status In Force
Filing Date 2010-02-19
Open to Public Date 2010-09-02
Grant Date 2019-10-29
Owner
  • KYOTO UNIVERSITY (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • JAPAN BIOLOGICAL INFORMATICS CONSORTIUM (Japan)
Inventor
  • Yamanaka, Shinya
  • Goshima, Naoki
  • Maekawa, Momoko
  • Kawamura, Yoshifumi
  • Mochizuki, Hiromi

Abstract

Reprogramming substances capable of substituting for K1f4, selected from the group consisting of members of the IRX family (e.g., IRX6), members of the GLIS family (e.g., GLIS1), members of the PTX family (e.g., PITX2), DMRTB1, and nucleic acids that encode the same, are provided. Also provided are a method of producing iPS cells, comprising the step of introducing into a somatic cell both one or more kinds of the above-described nuclear reprogramming substances and a substance capable of inducing iPS cells from a somatic cell when combined with K1f4. Still also provided are iPS cells comprising an extraneous nucleic acid that encodes any one of the above-described nuclear reprogramming substances, that can be obtained by the method, and a method of producing somatic cells by inducing the iPS cells to differentiate.

IPC Classes  ?

  • C12N 15/00 - Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

31.

FILM MADE FROM DENATURED CLAY

      
Document Number 02620021
Status In Force
Filing Date 2008-02-07
Open to Public Date 2009-08-07
Grant Date 2013-03-26
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Ebina, Takeo
  • Kobayashi, Kiyoshi
  • Ishii, Ryo
  • Okada, Tatsuhiro
  • Mizukami, Fujio

Abstract

The present invention provides a novel technology and a novel material having excellent pliability, gas barrier properties and water resistance, for the technical fields of packaging materials, sealing materials, electric insulating materials and the like, the present invention relates to a film of a material having a denatured clay as a main constituent thereof, wherein (1) the film comprises a denatured clay and an additive, (2) the weight ratio of the denatured clay is not less than 70% relative to total solids, (3) the film has gas barrier properties and water-vapor barrier properties, (4) the film has heat resistance, (5) the film has water resistance, (6) the film has sufficient mechanical strength to be used as a self-supporting film, and (7) the film can be formed on the surface of metals, plastics, rubber, paper and the like, and the present invention can provide a material comprising the denatured clay film in which denatured clay particles are highly oriented and which has excellent heat resistance, excellent pliability, excellent gas barrier properties, excellent water-vapor barrier properties, and high water resistance.

IPC Classes  ?

  • B32B 18/00 - Layered products essentially comprising ceramics, e.g. refractory products
  • B32B 27/08 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of synthetic resin of a different kind
  • B65D 65/40 - Applications of laminates for particular packaging purposes

32.

ORGANIC MATERIAL PRODUCTION SYSTEM USING BIOMASS MATERIAL AND METHOD

      
Document Number 02713529
Status In Force
Filing Date 2008-09-19
Open to Public Date 2009-08-06
Grant Date 2013-12-17
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (Japan)
  • MITSUBISHI POWER ENVIRONMENTAL SOLUTIONS, LTD. (Japan)
Inventor
  • Genta, Minoru
  • Uehara, Ryosuke
  • Fujita, Kinya
  • Sakaki, Tsuyoshi
  • Yamada, Noriyuki
  • Saito, Katsuichi
  • Hashimoto, Naoto
  • Hasa, Yasuhiro

Abstract

An organic material production system includes: a pretreatment device (12) that pulverizes a biomass material (11); a hydrothermal decomposition apparatus (14) that hydrothermally decomposes a pulverized biomass (13) by causing it to countercurrently contact with hot compressed water (15), elutes lignin components and hemicellulose components into the hot compressed water (15), and separates the lignin components and the hemicellulose components from a biomass solid residue; a first enzymatic hydrolysis device (19-1) that treats cellulose in a biomass solid residue (17), discharged from the hydrothermal decomposition apparatus, with an enzyme (18) to enzymatically hydrolyze it to a sugar solution containing hexose; a fermenter (21) that produces ethanol by fermentation using a sugar solution (20) obtained by the first enzymatic hydrolysis device (19-1); and a refiner 25 that refines an alcohol fermentation liquid (22), so as to separate it into ethanol (23) and a residue (24).

IPC Classes  ?

  • C12P 1/00 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymes; General processes for the preparation of compounds or compositions by using microorganisms or enzymes
  • C08H 8/00 - Macromolecular compounds derived from lignocellulosic materials
  • B01D 11/02 - Solvent extraction of solids
  • B01J 3/00 - Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
  • C12M 1/00 - Apparatus for enzymology or microbiology
  • C12M 1/42 - Apparatus for the treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave
  • C12P 7/02 - Preparation of oxygen-containing organic compounds containing a hydroxy group
  • C12P 7/10 - Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
  • C12P 19/00 - Preparation of compounds containing saccharide radicals
  • C12P 21/00 - Preparation of peptides or proteins
  • C13K 1/02 - Glucose; Glucose-containing syrups obtained by saccharification of cellulosic materials

33.

HYDROGEN SENSOR

      
Document Number 02688568
Status In Force
Filing Date 2008-05-28
Open to Public Date 2008-12-11
Grant Date 2016-03-15
Owner
  • KABUSHIKI KAISHA ATSUMITEC (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Uchiyama, Naoki
  • Yoshimura, Kazuki

Abstract

In hydrogen sensors (10a, 10b, 10c, 10d), a thin film layer (12) is formed on a substrate (11), and a buffer layer (13) is laminated on the thin film layer (12). Furthermore, a catalyst layer (14) is laminated on the buffer layer (13). The catalyst layer hydrogenates the thin film layer (12) when the catalyst layer is brought into contact with hydrogen gas and changes the optical reflectance of the thin film layer (12). Component diffused from the thin film layer (12) to the catalyst layer (14) are bonded with component diffused from the buffer layer (13) to the catalyst layer (14), and the catalyst layer (14) is prevented from being oxidized. As a result, the catalyst layer (14) or the like is prevented from being oxidized due to repetition of hydrogenation of the thin film layer (12), and deterioration of hydrogen detection sensitivity of the hydrogen sensors (10a, 10b, 10c, 10d) is suppressed.

IPC Classes  ?

  • G01N 31/00 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods
  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
  • G01N 31/10 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods using catalysis
  • G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods using chemical indicators

34.

HYDROGEN SENSOR AND HYDROGEN GAS DETECTING APPARATUS

      
Document Number 02670304
Status In Force
Filing Date 2007-07-10
Open to Public Date 2008-05-29
Grant Date 2015-04-28
Owner
  • KABUSHIKI KAISHA ATSUMITEC (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Uchiyama, Naoki
  • Matsuda, Naoki
  • Yoshimura, Kazuki
  • Kato, Kenji

Abstract

A thin film layer is formed on the surface of a planar light transmission path in a hydrogen sensor, and a catalyst layer is formed on the surface of the thin film layer. A first boundary surface is formed between the planar light transmission path and the thin film layer, and a second boundary surface is formed between the planar light transmission path and a substrate when the substrate is bonded to the backside of the planar light transmission path. Light from a light source is allowed to enter from the incident portion while being diffused to the first end side of the planar light transmission path, and then the light is reflected alternately off the first and second boundary surfaces and transmitted to the second end side of the planar light transmission path. That light exiting the second end side is transmitted to a photosensor by an exiting/condensing portion. When the thin film layer is hydrogenated by the catalyst layer touching hydrogen, the quantity of light reflecting off the first boundary surface decreases. Decrease in quantity of light is detected by the photosensor to thereby detect hydrogen.

IPC Classes  ?

  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
  • G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour

35.

ORAL COMPOSITION CONTAINING INTERFERON-.ALPHA.

      
Document Number 02636914
Status In Force
Filing Date 2007-01-12
Open to Public Date 2007-07-19
Grant Date 2016-08-09
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • HOKUSAN CO. LTD (Japan)
Inventor
  • Yoshioka, Kuniaki
  • Sato, Ko
  • Gotanda, Toru
  • Ito, Akira
  • Isogai, Emiko
  • Takehara, Kazuaki
  • Maehara, Nobutoshi

Abstract

The present invention provides oral compositions which contain interferon .alpha. (IFN.alpha.) as an active ingredient for preventing and/or treating periodontal disease. The number of causative microorganisms of periodontal disease can be suppressed by administering the compositions into the oral cavity. IFN.alpha. of the present invention can produce a sufficient effect even when administered at a very low dose. Furthermore, the compositions of the present invention can also be readily administered to animals such as dogs by formulating them into feed or such.

IPC Classes  ?

  • A61K 38/21 - Interferons
  • A61K 9/20 - Pills, lozenges or tablets
  • A61K 9/68 - Medicinal preparations characterised by special physical form chewing gum type
  • A61P 1/02 - Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
  • C12N 15/09 - Recombinant DNA-technology

36.

METHOD FOR PRODUCTION, SUBSTITUTION, OR MINING OF GAS HYDRATE

      
Document Number 02620456
Status In Force
Filing Date 2006-08-25
Open to Public Date 2007-03-01
Grant Date 2011-10-18
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor Ikegawa, Yojiro

Abstract

A gas hydrate is produced by injecting guest molecules into voids in a layer of which temperature and pressure condition allows the guest molecules to cause to form hydrate, in a form of emulsion where liquid of the guest molecules is dispersed in water as minute particles having a size of less than a size of voids, and thereby dispersing the guest molecules uniformly into the voids in the layer.

IPC Classes  ?

  • C10L 3/06 - Natural gas; Synthetic natural gas obtained by processes not covered by , or
  • B01J 19/00 - Chemical, physical or physico-chemical processes in general; Their relevant apparatus
  • C07B 63/02 - Purification; Separation specially adapted for the purpose of recovering organic compounds; Stabilisation; Use of additives by treatment giving rise to a chemical modification
  • C07C 5/00 - Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
  • C07C 7/20 - Use of additives, e.g. for stabilisation
  • C07C 9/04 - Methane

37.

TRANSPARENT FILM

      
Document Number 02617254
Status In Force
Filing Date 2006-08-02
Open to Public Date 2007-02-08
Grant Date 2012-09-18
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Ebina, Takeo
  • Mizukami, Fujio

Abstract

The present invention provides a novel technology and a novel transparent material having high thermal stability, excellent pliability, surface smoothness, dimensional stability and gas barrier properties, for the technical fields of packaging materials, sealing materials and display materials, and the invention relates to an inorganic layered compound film having oriented inorganic layered compound particles, exhibiting high surface smoothness, high dimensional stability, high transparency, excellent pliability, excellent gas barrier properties and high heat resistance, that is obtained by dispersing an inorganic layered compound of high transparency and a small amount of a water-soluble polymer of high transparency in water or a liquid having water as a main component thereof, to thereby obtain a homogeneous dispersion containing no agglomerates, applying thereafter this dispersion onto a support having a flat and water- repellent surface, to thereby effect deposition of inorganic layered compound particles, and separating the liquid, as a dispersion medium, according to any of various solid-liquid separation methods, for example, centrifugation, filtration, vacuum drying, vacuum freeze drying, evaporation by heating or the like to thereby attain formation into a film shape, and optionally followed by methods such as drying/heating/cooling to thereby effect detachment from the support.

IPC Classes  ?

  • C08L 101/14 - Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
  • C01B 33/12 - Silica; Hydrates thereof, e.g. lepidoic silicic acid
  • C01B 33/40 - Clays
  • C01G 23/047 - Titanium dioxide
  • C08J 5/18 - Manufacture of films or sheets
  • C08K 3/22 - Oxides; Hydroxides of metals
  • C08K 3/36 - Silica
  • C08K 7/00 - Use of ingredients characterised by shape

38.

HAPTIC INFORMATION PRESENTATION SYSTEM AND METHOD

      
Document Number 02547961
Status In Force
Filing Date 2004-11-19
Open to Public Date 2005-06-02
Grant Date 2013-04-30
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • MURATA MANUFACTURING CO., LTD (Japan)
Inventor
  • Nakamura, Norio
  • Fukui, Yukio
  • Sakai, Masataka

Abstract

A system and a method are realized in which in a conventional non-grounding man-machine interface having no reaction base on the human body and for giving the existence of a virtual object and the impact force of a collision to a person, a haptic sensation of a torque, a force and the like can be continuously presented in the same direction, which can not be presented by only the physical characteristic of a haptic sensation presentation device. In a haptic presentation device 112, the rotation velocity of at least one rotator in the haptic presentation device 112 is controlled by a control device 111, and a vibration, a force or a torque as the physical characteristic is controlled, so that the user 110 is made to conceive various haptic information of the vibration, force, torque or the like. The haptic information presentation system uses a human sensory characteristic or illusion to suitably control the physical quantity, and causes the person to feel a force which can not exist physically, or a haptic sensory physical characteristic.

IPC Classes  ?

  • G06F 3/00 - Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
  • B06B 1/04 - Processes or apparatus for generating mechanical vibrations of infrasonic, sonic or ultrasonic frequency making use of electrical energy operating with electromagnetism
  • G05D 19/02 - Control of mechanical oscillations, e.g. of amplitude, of frequency, of phase characterised by the use of electric means

39.

CLAY FILM

      
Document Number 02538173
Status In Force
Filing Date 2004-09-08
Open to Public Date 2005-03-17
Grant Date 2012-01-03
Owner NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Ebina, Takeo
  • Mizukami, Fujio

Abstract

The present invention provides a clay film with excellent flexibility, whose main component is natural clay or synthetic clay, and in which there is uniform orientation in the clay particle layer, and relates to a novel clay film that has enough mechanical strength to be used as a self-supporting film, and has a structure in which layers of clay particles are highly oriented, and in which the main constituent component of the clay film is mica, vermiculite, montmorillonite, iron montmorillonite, beidellite, saponite, hectorite, stevensite, or nontronite, and which has excellent flexibility, undergoes no structural change at high temperatures of 250°C and up to 600°C, contains no pinholes, and has a gas permeation coefficient of less than 3.2 x 10 -11 cm2s-1cmHg-1 at room temperature for helium, hydrogen, oxygen, nitrogen, or air.

IPC Classes  ?