Abstract

The purpose of present invention is to provide a local anesthetic-containing patch that is practical as a pharmaceutical in terms of skin permeability, aggregation power, and adhesiveness. The patch according to the present invention is characterized by having an adhesive agent layer on a support, wherein the adhesive agent layer contains at least a local anesthetic, a thermoplastic elastomer, a higher fatty acid ester, and a fatty acid monoester of a polyhydric alcohol, and the ratio of the higher fatty acid ester with respect to 100 parts by mass of the thermoplastic elastomer is 25-200 parts by mass.

IPC Classes  ?

• A61K 9/70 - Web, sheet or filament bases
• A61K 31/245 - Amino benzoic acid types, e.g. procaine, novocaine
• A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
• A61K 47/30 - Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
• A61P 23/02 - Local anaesthetics

Abstract

Hybrid organic/inorganic coating compositions of nanometer thickness are described, where the organic layer is a clay-containing layer comprising a clay and a hydrophilic polymer and the inorganic layer is a metal-containing layer comprising a metal with a refractive index greater than 1.5, where the coating compositions allow for the generation and tenability of iridescent color through control of the coat thickness.

IPC Classes  ?

• C01G 39/06 - Sulfides
• C01G 41/00 - Compounds of tungsten
• C09C 1/42 - Clays

Abstract

The present invention provides a glutathione-containing granular fertilizer that exhibits high preservation stability of glutathione and has sufficient strength. This glutathione-containing granular fertilizer comprises glutathione, a mineral, and starch, wherein the contained amount of the starch with respect to the total amount of the granular fertilizer is at least 12 mass%.

IPC Classes  ?

• C05F 11/10 - Fertilisers containing plant vitamins or hormones
• B01J 2/00 - Processes or devices for granulating materials, in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic

Abstract

Provided are expandable styrene resin particles containing graphite, which have specific physical properties, and wherein: the graphite content is 2.0-8.0% by weight per 100% by weight of the expandable styrene resin particles; and the graphite has an average particle diameter of 2.5-9 µm.

IPC Classes  ?

• C08J 9/18 - Making expandable particles by impregnating polymer particles with the blowing agent
• B29C 44/00 - Shaping by internal pressure generated in the material, e.g. swelling or foaming
• C08K 3/04 - Carbon
• C08L 25/06 - Polystyrene

Abstract

Provided is an oxidized glutathione (GSSG)-containing fertilizer that makes it possible to increase the stability of GSSG in environments such as soil and to continuously actualize the beneficial effects of GSSG on plants. The invention pertains to a slow-release fertilizer containing GSSG and a release-control agent.

IPC Classes  ?

• C05F 11/10 - Fertilisers containing plant vitamins or hormones
• C05G 3/40 - Mixtures of one or more fertilisers with additives not having a specifically fertilising activity for affecting solubility
• C05G 3/00 - Mixtures of one or more fertilisers with additives not having a specifically fertilising activity
• A01N 41/12 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom not containing sulfur-to-oxygen bonds, e.g. polysulfides
• A01P 21/00 - Plant growth regulators

Abstract

This high-visibility fiber fabric is a fiber fabric which has, on at least one surface of a colored fiber fabric, a colored area formed by applying a fluorescent-pigment-containing resin, wherein the fluorescent-pigment-containing resin has been applied to at least the whole surface of the colored area; and the color of the colored area satisfies "5.1 color performance requirements" and "5.2 color requirements after xenon test for light fastness" in ISO 20471:2013.

IPC Classes  ?

• D06M 15/19 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials with macromolecular compounds; Such treatment combined with mechanical treatment with synthetic macromolecular compounds
• A41D 31/04 - Materials specially adapted for outerwear characterised by special function or use
• A41D 31/00 - Materials specially adapted for outerwear
• A41D 31/02 - Layered materials
• D06B 11/00 - Treatment of selected parts of textile materials, e.g. partial dyeing
• D06M 15/564 - Polyureas, polyurethanes or other polymers having ureide or urethane links; Precondensation products forming them
• D06M 23/16 - Processes for the non-uniform application of treating agents, e.g. one-sided treatment; Differential treatment

Abstract

This invention relates to a plant having high resistance to environmental stress and high seed productivity, and, more particularly, a transformed plant that is genetically modified to overexpress a polyadenylate-binding protein (PABN) gene and has enhanced environmental stress resistance and enhanced seed productivity.

IPC Classes  ?

• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
• A01H 6/20 - Brassicaceae, e.g. canola, broccoli or rucola
• A01H 6/46 - Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize
• A01H 1/00 - Processes for modifying genotypes
• A01H 5/00 - Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
• C07K 14/415 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
• C12N 15/29 - Genes encoding plant proteins, e.g. thaumatin
• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells

Abstract

A method for producing a chlorinated vinyl chloride resin of the present invention includes chlorinating a vinyl chloride resin by irradiating the inside of a reactor, into which the vinyl chloride resin and chlorine have been introduced, with ultraviolet light, thereby producing a chlorinated vinyl chloride resin. The irradiation of ultraviolet light is carried out through use of at least one kind of light source selected from the group consisting of an ultraviolet LED, an organic EL, an inorganic EL, and an ultraviolet laser. A chlorinated vinyl chloride resin that shows suppressed initial coloring during hot forming and/or improved thermal stability can be provided by the method for producing a chlorinated vinyl chloride resin of the present invention.

IPC Classes  ?

• C08F 8/22 - Halogenation by reaction with free halogens

Abstract

A flameproof spun yarn of the present invention includes a modacrylic fiber containing an antimony compound and a polyarylate-based fiber, and the flameproof spun yarn contains 1 to 30 wt% of the polyarylate-based fiber relative to the total weight of the flameproof spun yarn. A flameproof fabric of the present invention includes a modacrylic fiber containing an antimony compound and a polyarylate-based fiber, and the flameproof fabric contains 1 to 30 wt% of the polyarylate-based fiber relative to the total weight of the flameproof fabric. And clothes and flameproof work clothes of the present invention include the flameproof fabric. The present invention thereby provides at a low cost a flameproof spun yarn and a flameproof fabric having excellent designability and flameproofness, and clothes and a flameproof work clothes using the same.

IPC Classes  ?

• D02G 3/04 - Blended or other yarns or threads containing components made from different materials
• A41D 13/00 - Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
• D01F 6/54 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polymers of unsaturated nitriles
• D01F 6/62 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters

Abstract

With respect to reduced coenzyme Q10, there has been no report about the presence of crystal polymorphism, and it has been considered that a conventionally obtained crystal form is only one form. The present invention relates to a reduced coenzyme Q10 crystal having an endothermic peak indicating melting at 54 ~ 2°C during temperature rise at a rate of 5°C/min by differential scanning calorimetry (DSC), and/or to a reduced coenzyme Q10 crystal showing characteristic peaks at diffraction angles (2.theta. ~ 0.2°) of 11.5°, 18.2°, 19.3°, 22.3°, 23.0° and 33.3° by powder X-ray (Cu-K.alpha.) diffraction. The crystal form is a novel reduced coenzyme Q10 crystal which has a higher melting point and a lower solubility in a solvent, and is more excellent in stability than the conventionally known reduced coenzyme Q10 crystal.

IPC Classes  ?

• C07C 43/23 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
• A61K 8/35 - Ketones, e.g. quinones, benzophenone
• A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• A61P 3/02 - Nutrients, e.g. vitamins, minerals
• C07C 41/40 - Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation

Abstract

It is an object of the present invention to inexpensively provide arc protection work clothing that is lighter than that of the conventional art; specifically, fabric and arc protection work clothing having a specific ATPV of not less than 1.3 (cal .cndot. yd2)/(cm2.cndot. oz). The fabric contains 40 to 65% by weight of modacrylic fibers based on the fabric weight, the modacrylic fibers containing at least 8% by weight of antimony oxide relative to the resin weight of the modacrylic fibers, 26 to 45% by weight of natural cellulosic fibers, 5 to 15% by weight of nylon fibers, and 1 to 20% by weight of para-aramid fibers, and arc protection work clothing can be made from the fabric.

IPC Classes  ?

• D03D 15/00 - Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used
• A41D 31/08 - Heat resistant; Fire retardant
• D03D 15/283 - Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the material of the fibres or filaments constituting the yarns or threads synthetic polymer-based, e.g. polyamide or polyester fibres
• D03D 15/513 - Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used characterised by the properties of the yarns or threads heat-resistant or fireproof
• A41D 13/00 - Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
• D01F 6/40 - Modacrylic fibres, i.e. containing 35 to 85% acrylonitrile
• D01F 6/54 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polymers of unsaturated nitriles
• D02G 3/04 - Blended or other yarns or threads containing components made from different materials
• D02G 3/44 - Yarns or threads characterised by the purpose for which they are designed

Abstract

The present invention has its object to provide a liquid-applied moisture-permeable waterproofing material that can protect a building from rainwater or humidity in the air, can drain moisture, which has been gathered on a substrate of a building, and can be applied easily. The present invention is a curable composition comprising: (A) a polyoxyalkylene polymer having a silicon-containing group crosslinkable by forming a siloxane bond; (B) a polyoxyalkylene plasticizer whose main chain contains 5 wt% or more of an oxypropylene-derived repeating unit and has one or more groups, at an end thereof, selected from the group consisting of an -OH group, a group represented by the formula: -OR9 (wherein R9 is a substituted or unsubstituted C1-20 hydrocarbon group), and a group represented by the formula: -NR10 2 (wherein R10 is each independently a hydrogen atom, or a substituted or unsubstituted C1-20 hydrocarbon group).

IPC Classes  ?

• C08L 71/02 - Polyalkylene oxides

Abstract

Disclosed are: a gene transfer method which can achieve the transformation of a plant belonging to the genus Triticum with higher efficiency compared to the conventional Agrobacterium methods; and a method for producing a transgenic plant. The methods are characterized by comprising a step of culturing a plant tissue into which an Agrobacterium bacterium has been inoculated in a co-culture medium and subsequently removing at least one part selected from a radicle, a budlet and a hypocotyl from the cultured tissue.

IPC Classes  ?

• A01H 1/00 - Processes for modifying genotypes

Abstract

The present invention has its object to provide a method and a device or kit for detecting a nucleic acid, which enable simple and precise visual detection of a nucleic acid amplified by a nucleic acid amplification method, without necessity of a special device. The present invention relates to a method for detecting a nucleic acid in a sample, comprising the steps of: (1) contacting a sample with a dye to react with each other; and (2) observing a substance produced by the reaction with visible light, and evaluating the presence of a nucleic acid by eye. The present invention also relates to a device or kit for detecting a nucleic acid in a sample, comprising: a carrier (a) that holds a dye which can bind to a nucleic acid; a path (c) for passing a sample through (a) the carrier; and an evaluation part (d) for observing a substance produced by the reaction between the sample and the dye with visible light, and evaluating the presence of a nucleic acid by eye.

IPC Classes  ?

• C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper

Abstract

An object is to provide a material capable of removing A.beta. from a body fluid efficiently and use of the material, which are developed for the purpose of establishing a therapeutic or preventive method for Alzheimer's disease. Provided is an amyloid .beta. protein remover, containing a carrier made of any one material selected from the group consisting of cellulose, silica, polyvinyl alcohol, and activated carbon, wherein the carrier does not have an alkyl chain on the surface thereof or has an alkyl chain having 1 to 18 carbon atoms on the surface thereof.

IPC Classes  ?

• A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
• A61M 1/02 - Blood transfusion apparatus

Abstract

Disclosed is a method for improving the efficiency of the transformation in a plant compared to a conventional Agrobacterium-mediated method. As one of the characteristics, the method comprises a co-culture step for culturing a plant tissue inoculated with an Agrobacterium in a co-culture medium containing 3,6-dichloro-o-anisic acid.

IPC Classes  ?

• A01H 1/00 - Processes for modifying genotypes
• C12N 15/09 - Recombinant DNA-technology

Abstract

This invention provides an organic rare earth metal complex, which emits fluorescence with a wavelength in the range of 550 to 900 nm, particularly a fluorescent resin composition comprising an ethylene-vinyl acetate copolymer containing 0.01 to 10% by mass of an organic rare earth metal complex represented by general formula (see above formula), wherein R represents an aliphatic or aromatic hydrocarbon group; Ln represents a rare earth metal; A represents group -CH=CH-; and n is 0 or 1. There are also provided a solar battery module using the fluorescent resin composition as a sealing material between a front cover and a crystalline silicon cell, and a solar battery with high conversion efficiency.

IPC Classes  ?

• C08L 31/04 - Homopolymers or copolymers of vinyl acetate
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials

Abstract

The present invention provides a particulate composition wherein an oil component containing reduced coenzyme Q10 is polydispersed forming a domain in a matrix containing a water-soluble excipient, which simultaneously shows high oxidative stability and high oral absorbability, a production method thereof, and a stabilizing method thereof. It also provides a food, food with nutrient function claims, food for specified health uses, dietary supplement, nutritional product, animal drug, drink, feed, pet food, cosmetic, pharmaceutical product, therapeutic drug, prophylactic drug and the like, which contain the composition.

IPC Classes  ?

• A61K 31/09 - Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
• A61K 9/14 - Particulate form, e.g. powders
• A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
• A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
• A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
• A61K 47/36 - Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 47/38 - Cellulose; Derivatives thereof
• A61P 3/02 - Nutrients, e.g. vitamins, minerals

Abstract

Disclosed is a novel vector for plant transformation. The vector is a cosmid vector having the entire length of 15 kb or shorter and also having the following properties: 1) the vector contains a replication initiation point for IncP plasmid but does not contain a replication initiation point for other plasmid; 2) the vector contains trfA1 gene for IncP plasmid; 3) the vector contains oriT for IncP plasmid; 4) the vector contains incC1 gene for IncP plasmid; 5) the vector contains a cos site for a lambda phage and the cos site is located outside of T-DNA; 6) the vector contains a drug-resistant gene which can be expressed in Escherichia coli and a bacterium belonging to the genus Agrobacterium; 7) the vector contains a right T-DNA-border sequence for a bacterium belonging to the genus Agrobacterium; 8) the vector contains a left T-DNA-border sequence for a bacterium belonging to the genus Agrobacterium; 9) the vector contains a selective marker gene for plant transformation, wherein the selective marker gene is located between the sequences mentioned in 7) and 8) and can be expressed in a plant; and 10) the vector contains a restriction enzyme recognition site for cloning of a foreign gene, wherein the restriction enzyme recognition site is located between the sequences mentioned in 7) and 8).

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12N 1/21 - Bacteria; Culture media therefor modified by introduction of foreign genetic material
• C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

Abstract

The present invention aims at providing a method of stabilizing reduced coenzyme Q10 useful as food, food with nutrient function claims, food for specified health use, nutritional product, nutritional supplement, animal drug, drink, feed, cosmetic, pharmaceutical product, therapeutic drug, prophylactic drug and the like, as well as a composition thereof. The present invention provides a method of stabilizing reduced coenzyme Q10, including achieving the co-presence of reduced coenzyme Q10 and reduced coenzyme Q9 and/or reduced coenzyme Q11, and a composition containing reduced coenzyme Q10 and reduced coenzyme Q9 and/or reduced coenzyme Q11.

IPC Classes  ?

• C07C 41/46 - Use of additives, e.g. for stabilisation
• A61K 8/35 - Ketones, e.g. quinones, benzophenone
• A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
• A61K 9/50 - Microcapsules
• A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• A61P 3/02 - Nutrients, e.g. vitamins, minerals
• C07C 41/26 - Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
• C07C 41/34 - Separation; Purification; Stabilisation; Use of additives
• C07C 43/23 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups

Abstract

The present invention provides a process for crystallizing a polymer having at least 20 mole percent of hydroxyalkanoate repeat units, comprising admixing the polymer and a compound of the formula R1-C(O)N(R2)2, R1-C(O)NH-(R3)-NHC(O)- R1, R1-NHC(O)NH-(R3)-NHC(O)NH-R1, R1-NHC(O)-R2, R1-NHC(O)-(R3)-C(O)NH-R1, R1- C(O)NH-(R3)-C(O)NH-R1, R1-NHC(O)NH-(R3)-C(O)NH-R1, R1-NHC(O)NH-(R3)-NHC(O)-R1, or a combination thereof, at a first temperature, which is from about 5~C to about 15~C above the melting point of the polymer; and cooling the polymer at a second temperature, which is from about the glass transition temperature of the polymer to about the melting point of the compound. The present invention also provides a composition comprising a polymer having at least about 20 mole percent of hydroxyalkanoate repeat units, and a compound of the formula R1- C(O)N(R2)2, R1-C(O)NH-(R3)-NHC(O)-R1, R1-NHC(O)NH-(R3)-NHC(O)NH-R1, R1-NHC(O)- R2, R1-NHC(O)-(R3)-C(O)NH-R1, R1-C(O)NH-(R3)-C(O)NH-R1, R1-NHC(O)NH-(R3)- C(O)NH-R1, R1-NHC(O)NH-(R3)-NHC(O)-R1, or a combination thereof.

IPC Classes  ?

• C08K 5/20 - Carboxylic acid amides
• C08K 5/21 - Urea; Derivatives thereof, e.g. biuret
• C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones

Abstract

It is intended to provide a method of transferring a gene into a plant material via a bacterium belonging to the genus Agrobacterium which comprises: 1) treating the plant material; and 2) infecting the plant material with the agrobacterium; characterized in that, in the above steps 1) and/or 2), use is made of a medium having a metal salt containing copper ion at an elevated concentration. It is also intended to provide a method of constructing a transformant plant characterized by using the gene transfer method as described above.

IPC Classes  ?

• C12N 15/09 - Recombinant DNA-technology
• A01H 4/00 - Plant reproduction by tissue culture techniques
• C12N 5/14 - Plant cells

Abstract

A method of infusing a gene in a plant material via a bacterium of the Agrobacterium genus. This method is characterized in that it includes treating a plant material under pressure (1) and thereafter infecting the plant material with Agrobacterium (2).

IPC Classes  ?

• C12N 15/84 - Ti-plasmids
• A01H 1/00 - Processes for modifying genotypes

Abstract

A pharmaceutical composition having excellent peroral absorbability and comprising coenzyme Q10 as the active ingredient. In this composition, the coenzyme Q10 comprises more than 20 % by weight of reduced coenzyme Q10.

IPC Classes  ?

• A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin