This disclosure generally relates to a flux-limiting polymer membrane for an analyte sensor and to an analyte sensor having a flux-limiting polymer membrane.
A method for producing an analyte sensor is disclosed. A first substrate having a first side and a second side is provided. The second side has a first layer having a first conductive material. A second substrate having a first side and a second side is provided. The first side has a second layer having a second conductive material. The second side of the second substrate has a third layer having a third conductive material. A conductive preparation is applied onto at least one of the first side of the first substrate and the third layer or a portion thereof to form a conductive preparation layer. The conductive preparation has conductive particles and a polymeric binder. The first side of the first substrate is laminated with the second side of the second substrate. An analyte sensor is obtained.
The present invention relates to a method for the preparation of a working electrode, the method comprising application of a sensing material in several steps. Further, the present invention relates to an analyte sensor comprising the working electrode as well as to the use of the analyte sensor for detecting at least one analyte in a sample.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
The present disclosure refers to a method for operating a system, the system comprising a medical device, having at least one of a sensor device for sensing medical data and a medication delivery device for delivering medication, a portable electronic consumer device, an intermediate device provided with a first communication protocol for data communication with the portable electronic consumer device and a second communication protocol for data communication with the medical device, and a control module provided in the intermediate device, the method comprising, in the control module, receiving control data from the portable electronic consumer device by a receiving functionality provided in the control module, the control data being configured for controlling operation of the medical device, determining whether the control data can be confirmed by a confirmation functionality provided in the control module, and if the control data are confirmed, transmitting the control data to the medical device by a transmission functionality provided in the control module. Further, a system is provided.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
5.
METHOD FOR MANUFACTURING AT LEAST ONE ELECTRODE OF AN ANALYTE SENSOR
A method for manufacturing at least one electrode (110) of an analyte sensor (112) is disclosed. The method comprises the following steps:
a) providing (116) a stencil (118), wherein the stencil (118) comprises a first stencil side (120), a second stencil side (122) and at least one through hole (124) reaching from the first stencil side (120) to the second stencil side (122), wherein at least one of the first stencil side (120) and the second stencil side (122) has first wettability properties;
b) providing (126) a substrate (128), wherein the substrate (128) comprises a first side (130) and a second side (134);
c) applying (136) the stencil (118) to the first side (130) of the substrate (128);
d) applying (138) a low viscosity composition (140) into the through hole (124) of the stencil (118), wherein the low viscosity composition (140) has second wettability properties opposing to the first wettability properties of the at least one of the first stencil side (120) and the second stencil side (122);
e) drying (141) the low viscosity composition (140);
f) obtaining (142) the at least one electrode (110).
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
H05K 3/12 - Apparatus or processes for manufacturing printed circuits in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern using printing techniques to apply the conductive material
6.
ANALYTE SENSOR SYSTEM AND A METHOD FOR ITS PRODUCING
An analyte sensor system (110) and a method (160) for producing an analyte sensor system (110) are disclosed. Herein, the analyte sensor system (110) comprises:
an analyte sensor having
a first contact pad, and
a second contact pad;
a circuit carrier having
a first contact area, and
a second contact area, wherein the second contact area comprises at least two individual electrically conductive surfaces; and
a connecting element electrically connecting the second contact pad of the analyte sensor with each of the at least two individual electrically conductive surfaces of the second contact area of the circuit carrier.
An analyte sensor system (110) and a method (160) for producing an analyte sensor system (110) are disclosed. Herein, the analyte sensor system (110) comprises:
an analyte sensor having
a first contact pad, and
a second contact pad;
a circuit carrier having
a first contact area, and
a second contact area, wherein the second contact area comprises at least two individual electrically conductive surfaces; and
a connecting element electrically connecting the second contact pad of the analyte sensor with each of the at least two individual electrically conductive surfaces of the second contact area of the circuit carrier.
The analyte sensor system (110) as proposed herein allows a reliable and persistent electrical contact between the analyte sensor (112) and the circuit carrier (114) which minimizes a risk of short circuits.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
7.
DIFFUSION BARRIERS AND SPACER MEMBRANES FOR ENZYMATIC IN-VIVO SENSORS
An electrode system is disclosed for measuring a concentration or presence of an analyte under in-vivo conditions, where the electrode system includes at least one electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. The diffusion barrier includes a hydrophilic polyurethane or a block copolymer having at least one hydrophilic block and at least one hydrophobic block. The electrode system also can include a spacer membrane that includes a hydrophilic copolymer of acrylic and/or methacrylic monomers.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using enzyme electrodes, e.g. with immobilised oxidase
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
8.
METHOD OF CONTROLLING AUTO-EXPOSURE SETTINGS OF A MOBILE DEVICE HAVING A CAMERA
A method is disclosed for controlling auto-exposure settings of a mobile device when capturing an image of a color reference card and of a test field. Provided are a color reference card and an optical test strip having the test field with a sample applied thereto. The color reference card has different color reference fields having known reference color values and one or more gray background fields having defined gray values. An exposure metering area is set and auto-exposure settings are determined based on a scene in the exposure metering area. The scene has at least part of the test field and at least part of the different color reference fields and the one or more gray background fields. The camera captures an image of the scene using the determined auto-exposure settings. A method of determining concentration of analyte in a sample by using a mobile device is also disclosed.
This disclosure relates to a method of manufacturing an in vivo analyte sensing device, which is adapted for detecting at least one analyte in a body fluid or tissue and an in vivo analyte sensing device obtainable by said manufacturing method. Further, this disclosure relates to a method of manufacturing a sensor base plate and a sensor base plate obtainable by said manufacturing method. The sensor base plate may be used for the manufacture of an in vivo analyte sensing device.
A method for detecting a failure of at least one component of a continuous analyte monitoring system is disclosed. The continuous analyte monitoring system has a failure detection resistor and an analyte sensor having at least two measurement electrodes. A constant voltage is applied between the two measurement electrodes and a first response signal is measured. A failure detection signal that is distinguishable from the constant voltage and/or from the first response signal in frequency and/or in height is applied to the continuous monitoring system, and a second response signal to the failure detection signal is measured using the failure detection resistor. Information is determined depending on at least one actual property of the component by evaluating the first response signal and the second response signal. A failure is detected if the information deviates from an expected value by more than a predetermined tolerance.
A method of determining concentration of an analyte in a body fluid uses a mobile device having a camera and an ambient light detector. The ambient light detector has an ambient light sensor and/or an additional camera. An ambient light check is performed. In the ambient light check, ambient light is used to determine an item of ambient light information. If a validity criterion is determined to be met, the concentration of the analyte is determined by evaluating an image of at least a part of a reagent test region of an optical test strip having a sample of body fluid applied thereto. The image is captured by the camera. A mobile device, a kit, a computer program and a computer-readable storage medium are also disclosed.
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
G01J 1/42 - Photometry, e.g. photographic exposure meter using electric radiation detectors
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
12.
INSERTION DEVICE AND METHOD FOR INSERTING A MEDICAL DEVICE
An insertion device includes an insertion component that inserts a medical device into body tissue of a user. The insertion device also includes an insertion component retractor, a cap, a guide sleeve having a ramp, an insertion sleeve and an elastic member. For inserting the medical device, the cap, the insertion component retractor and the insertion sleeve are movable relative to the guide sleeve from a distal position to a proximal position. The ramp twists the insertion component retractor relative to the guide sleeve and the insertion sleeve when the cap is moved from its distal position to its proximal position. The cap is movable from its proximal position to its distal position and the insertion component retractor is thereby moved from its proximal position to its distal position. An associated method of using the insertion device is also disclosed.
The present invention relates to a biosensor for determining an analyte comprising a substrate, a working electrode comprising an electrically conductive pad in conductive contact with a mediator layer, and an enzyme layer in diffusion-enabling contact with said mediator layer, wherein said mediator layer is an electrodeposited mediator layer, and wherein said mediator layer comprises, in an embodiment consists of, an electrocatalytic agent. The present invention further relates to a method for manufacturing a biosensor, comprising providing a substrate having at least one conductive pad, electrodepositing a mediator layer onto at least part of said conductive pad, wherein said mediator layer comprises, in an embodiment consists of, an electrocatalytic agent, and depositing an enzyme layer onto at least part of said mediator layer. Moreover, the present invention relates to uses and methods related to the biosensor of the present invention.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
C12Q 1/28 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/1486 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using enzyme electrodes, e.g. with immobilised oxidase
14.
APPARATUS FOR INSERTING A MEDICAL DEVICE INTO A BODY TISSUE
An apparatus for medical purposes is disclosed. The apparatus includes a medical device configured to be at least partially insertable into body tissue of a user. It also includes an inserter configured for at least partially inserting the medical device into the body tissue. A housing has a removable cap connected thereto, and the removable cap is removed from the housing before insertion of the medical device. A flexible connector connects the removable cap to the housing, the flexible connector being reversibly displaceable from a locking position in which the removable cap is secured to the housing and a releasing position in which the removable cap is released from the housing. A frangible securing element secures the flexible connector into the locking position prior to use. Further, methods for preparing the apparatus and inserting the medical device into the body tissue of the user are disclosed.
A method for operating a medical device includes activating a processor that receives electrical power from a battery in the medical device, measuring a temperature within a housing of the medical device, identifying a low battery voltage threshold based on the temperature, measuring a first voltage level of the battery, commencing an operation sequence after measuring the first voltage level of the battery, generating a plurality of voltage comparisons between a reference voltage level and a voltage level delivered from the battery during the operation sequence, and generating, an output indicating a low battery condition if at least one of the first voltage level of the battery is less than the low battery voltage threshold and above a predetermined minimum operating voltage threshold, or at least one voltage comparison indicating the voltage level of the battery is less than the reference voltage level during the operation sequence.
A fully or partially implantable analyte sensor for continuously monitoring analyte concentration in a body fluid has a substrate with a first surface configured to face towards the body fluid. The sensor has a working electrode and an interferent electrode. The interferent electrode and the working electrode are electrically separated layers located adjacently on the first surface. The sensor has a further electrode, the further electrode being a counter electrode, a reference electrode or a counter/reference electrode. The working electrode and the interferent electrode each have a layer of a conductive material. The working electrode has an enzyme whereas the interferent electrode is devoid of enzyme. A method for producing the fully or partially implantable analyte sensor for continuously monitoring analyte concentration in a body fluid is also disclosed.
A test strip fixation device for use in a method of determining analyte concentration in a body fluid using a mobile device with a camera. The device has top and bottom surfaces, has an essentially planar shape, and also has a cut-out portion configured for application of a body fluid sample. The top surface has color reference fields with known reference color values, including grey and non-grey reference fields. The grey reference fields are symmetrically arranged around the cut-out portion and around at least some of the non-grey color reference fields. The top surface also has position detection code elements. The bottom surface has a connector configured for detachable connection of an optical test strip relative to the test strip fixation device, and a reagent test region of the test strip can be aligned with the cut-out portion. A method of using the device is also disclosed.
G01N 21/84 - Systems specially adapted for particular applications
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
This disclosure relates to a computer-implemented method, a mobile device, and a computer readable storage medium, for displaying a medical value such as, e.g., a glucose value, on a screen of a mobile device.
G06F 3/04817 - Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance using icons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
H04M 1/72463 - User interfaces specially adapted for cordless or mobile telephones with means for adapting the functionality of the device according to specific conditions to restrict the functionality of the device
19.
METHOD FOR DETERMINING AN ANALYTE CONCENTRATION IN A FLUID
A method for determining an analyte concentration in a fluid using an analyte sensor having at least two measurement electrodes is disclosed. One of the measurement electrodes has an analyte-responsive polymer gel. The method includes contacting at least the analyte-responsive polymer gel with the fluid having the analyte, generating a non-continuous fast-transient voltage signal and applying the non-continuous fast-transient voltage signal to the measurement electrodes, measuring a response signal, and evaluating the response signal to determine the analyte concentration.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
20.
METHOD OF PERFORMING AN ANALYTICAL MEASUREMENT USING A MOBILE DEVICE
A method of performing an analytical measurement includes using a camera of a mobile device to capture a time series of images of at least a part of a medical article. From this, image-derived position information on a relative position of the mobile device and the medical article is derived, thereby generating a first time series of position information. A sensor captures measurement information on the relative position of the mobile device and the medical article. Measurement-derived position information is used to generate a second time series of position information, and the first and second time series of position information are combined to generate an augmented time series of position information. From this, guidance is provided to a user to move the mobile device and the medical article into a relative target position. A mobile device, a kit and a computer program are also disclosed.
G01N 21/84 - Systems specially adapted for particular applications
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
This disclosure relates to an analyte sensor having a substrate, a working electrode, a second electrode and a membrane. The membrane is located on top of the second electrode. This disclosure further relates to a process for manufacturing the inventive analyte sensor as well as to an analyte sensor system having an analyte sensor according to this disclosure and an electronics unit. The analyte sensors according to this disclosure may be used for conducting an analyte measurement in a body fluid of a user.
A system and method for controlling recall of a product in a computer network. A pair of product keys can be assigned to the product including a private product key and a public product key. A pair of product recall keys can be assigned to a product recall, including a private product recall key and a public product recall key. A data processing device assigned to a manufacturer in the computer network can be configured to print a matrix code on the product and generate a recall transaction assigned to the product indicating a recall request for the product. The data processing device can sign the recall transaction with the private product recall key and a private manufacturer key. A second data processing device is configured to scan the printed matrix code on the product and provide the public product recall key by decrypting the printed matrix code.
G06K 1/12 - Methods or arrangements for marking the record carrier in digital fashion otherwise than by punching
G06K 7/14 - Methods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
H04L 9/06 - Arrangements for secret or secure communications; Network security protocols the encryption apparatus using shift registers or memories for blockwise coding, e.g. D.E.S. systems
H04L 9/30 - Public key, i.e. encryption algorithm being computationally infeasible to invert and users' encryption keys not requiring secrecy
24.
Method and System for Secure Interoperability between Medical Devices
A method for secure interoperability between an electronic device and a medical device has been developed. The method includes executing a control application configured to provide communication between the electronic device and medical device, receiving user authentication data from an authentication service, receiving a key identifier from the medical device via an untrusted connection, and transmitting a message with an identifier of the user, the user authentication data, the key identifier, an identifier of the control application, and a cryptographic signature to an authorization service. The method further includes receiving a medical device cryptographic key from the authorization service only in response to successful verification of the message to enable at least one of control communication and data communication between the control application and the medical device.
H04L 9/32 - Arrangements for secret or secure communications; Network security protocols including means for verifying the identity or authority of a user of the system
A method of determining the concentration of an analyte in a sample of a body fluid with a mobile device having a camera is disclosed. The camera captures an image of a color reference card and of a reagent test field of an optical test strip having a sample applied to it. A predetermined pixel-based mean tone map correction is applied to the image obtained, which results in a first intensity-corrected image. Local brightness information is derived from the first intensity-corrected image. A mobile device-specific tone map correction is applied to the first intensity-corrected image, taking into account the local brightness information. A second intensity-corrected image is thereby obtained. Analyte concentration is determined based on a color formation reaction of the test field by using the second intensity-corrected image. Optionally, a color correction may be derived and applied to the second intensity-corrected image to obtain an intensity-corrected and color-corrected image.
G06V 10/60 - Extraction of image or video features relating to illumination properties, e.g. using a reflectance or lighting model
26.
METHOD AND SYSTEM FOR GENERATING A SOFTWARE-IMPLEMENTED MODULE FOR DETERMINING AN ANALYTE VALUE, COMPUTER PROGRAM PRODUCT, AND METHOD AND SYSTEM FOR DETERMINING AN ANALYTE VALUE
A method for generating a software-implemented module for determining a glucose value in a body fluid. A first set of input data indicative of first values measured for first and a second input parameters is provided. A second set of input data indicative of second values for the first and second input parameters is also provided. The first and second sets of input data are processed by a physiological model to determine first and second sets of glucose values, respectively, in a body fluid. Training data is determined and a set of test data different from the training data is also determined. A software-implemented machine learning model configured to determine a glucose value in a body fluid of a patient is provided and is trained by the training data and is tested by the test data.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A method of evaluating the quality of a color reference card having multiple color reference fields. The quality refers to whether the color reference card is usable for a method for determining concentration of analyte in a body fluid and/or to the degree of suitability or reliability of the color reference card for use with a method for determining analyte concentration in a body fluid. In the inventive method, an image is captured of at least a part of the color reference card using a mobile device camera. Measured color reference values are determined from the image for one or more of the color reference fields and a relationship between one or more of the measured reference color values and corresponding known reference color values is determined. The determined relationship is used to assess the quality of the color reference card. A kit and mobile device are also disclosed.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01J 3/52 - Measurement of colour; Colour measuring devices, e.g. colorimeters using colour charts
G01N 21/29 - Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using visual detection
G01N 21/84 - Systems specially adapted for particular applications
28.
ANALYTE SENSOR AND A METHOD FOR PRODUCING AN ANALYTE SENSOR
A fully or partially implantable analyte sensor for continuously monitoring analyte concentration in a body fluid has a substrate with a first surface configured to face towards the body fluid. The sensor has a working electrode and an interferent electrode. The interferent electrode and the working electrode are electrically separated layers located adjacently on the first surface. The sensor has a further electrode, the further electrode being a counter electrode, a reference electrode or a counter/reference electrode. The working electrode and the interferent electrode each have a layer of a conductive material. The working electrode has an enzyme whereas the interferent electrode is devoid of enzyme. A method for producing the fully or partially implantable analyte sensor for continuously monitoring analyte concentration in a body fluid is also disclosed.
A method for storing measurement data detected by a sensor and indicative of an analyte in a body fluid sample using a system having a processor and a memory. First and second measurement data indicative of first and second measurement values measured by a sensor, respectively, are provided. A relative measurement value is determined by the processor and is indicative of a value difference between the first and second measurement values. The first measurement value is stored in a first storage area having a first storage size in the memory. The relative measurement value is stored in a second storage area having a second storage size in the memory that is smaller than the first storage size. An indicator is also stored in the memory and is assigned to the relative measurement storage data in the memory and is indicative of a characteristic of the relative measurement storage data.
A method for determining a membrane property of an analyte sensor that has at least two measurement electrodes and at least one of the measurement electrodes has a membrane having the membrane property. The method includes generating a fast-transient voltage signal and applying the fast-transient voltage signal to the measurement electrodes. A response signal is measured, and the membrane property is determined by evaluating the response signal.
A method of preparing a working electrode on a sensor substrate is disclosed. A sensor substrate is provided and has a first side with at least one conductive trace. A layer of sensing material is applied onto the first side and covers at least a portion of the at least one conductive trace. The sensing material is irradiated with a laser beam to partially remove the layer of the sensing material while preserving a portion of the sensing material covering the at least one conductive trace, resulting in a working electrode on the sensor substrate. A membrane layer is applied that at least partially covers the working electrode. The membrane layer includes a cross-linker that cross-links at least a part of the sensing material. A diffusion step is performed during which the cross-linker in the membrane layer at least partially diffuses into the sensing material.
A medical system is disclosed. The medical system has a housing and a module received in the housing. The module includes an analyte sensor configured for detecting an analyte in a body fluid of a user, an electronics unit electrically connected to the analyte sensor, an insertion component configured for inserting the analyte sensor into body tissue of the user, and a sterility cap at least partially surrounding the insertion component. A removable protective cap is connected to the housing and covers the module. The protective cap at least partially surrounds the sterility cap. The sterility cap has a sterility testing access that has at least one of a septum and a multiple-step sealing. A method of sterility testing the medical system is also disclosed in which a rinsing liquid is inserted into an interior space of the sterility cap and microbial testing of the rinsing liquid is then completed.
An analytical method for determining a concentration of an analyte is disclosed. In this method, an image of an optical test strip having a body fluid applied thereto is obtained with a camera of a mobile device. Local temperature information is received at a current location of the mobile device from a temperature source such as a remote weather information service or temperature sensor. Additional local temperature information is received by the mobile device from a thermochromic field provided on the test strip and/or on a color reference card. A processor determines a correction temperature and/or a correction temperature function using the local temperature information. The processor also determines the analyte concentration from the image captured and taking into account the correction temperature information.
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
35.
DEVICE FOR COLLECTION OF VOLATILE COMPOUNDS FROM SKIN FOR NON-INVASIVE MEASUREMENT OF BLOOD-GLUCOSE VALUES
A volumetric sampling apparatus for volatile compounds comprises a structure, such as a channel structure that forms a continuous curve between the inlet port and the outlet port. A gas flow induced in the structure urges volatile compounds collected via transdermal diffusion toward the outlet port, where the volatile compounds may be collected and analyzed by a gas composition analyzer coupled to the outlet port.
A method for monitoring medical data is disclosed, the method being applicable to a system comprising a portable medical device, a mobile communications device, and, optionally, a medical care server. The portable medical device and the mobile communications device each comprise at least one interface for data transfer. The method comprises a step of establishing a download link between the mobile communications device and a download server. The method comprises a step of selecting an appropriate communication software package from a plurality of communication software packages for controlling data transfer between the mobile communications device and the portable medical device from the download server. Further, the method comprises a download step for downloading communication software packages from the download server to the mobile communications device and a step of installation of the communication software package on the mobile communications device.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G06F 7/10 - Selecting, i.e. obtaining data of one kind from those record carriers which are identifiable by data of a second kind from a mass of ordered or randomly-distributed record carriers
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
37.
DMS - INTERACTIVE PRODUCT IDENTIFICATION FOR A CALL CENTER
This disclosure lies in the field of a computer implemented method of routing a video call from a call center computer system comprising a controller, a transceiver, and a machine learning system, to a product service agent computer system assigned to a certain medical device product type and associated services. This disclosure involves using artificial intelligence in order to identify a medical device product based on recorded product image data. Further aspects of this disclosure provide a corresponding call center computer system for routing a video call initiated by a mobile device from the call center computer system to a medical device product service agent computer system as well as a computer-implemented method for generating a model of a medical device product type.
G08B 13/196 - Actuation by interference with heat, light, or radiation of shorter wavelength; Actuation by intruding sources of heat, light, or radiation of shorter wavelength using passive radiation detection systems using image scanning and comparing systems using television cameras
H04N 7/18 - Closed-circuit television [CCTV] systems, i.e. systems in which the video signal is not broadcast
A computer-implemented diabetes management method includes a first determination of an insulin bolus related to one or more obtained glucose values and optionally the expected carbohydrate content of a meal to be ingested, a re-calculation of an insulin bolus in consideration of a user's body parameter information as measured by a body-worn sensor, providing a notification to the user if there is a significant deviation between the two calculated bolus amounts, and a user input whether the calculated insulin bolus or the re-calculated insulin bolus is selected by the user for bolus administration.
This disclosure refers to an adjustment method for adjusting a setup for an analytical method of determining a concentration of an analyte in a bodily fluid based on a color formation reaction in an optical test strip mobile device for performing analytical measurements. This disclosure further relates to a mobile device configured for performing the adjustment method, a computer program and a computer-readable storage medium for performing the adjustment method and a kit comprising a test strip or a dummy test strip and at least one of the mobile device, the computer program and the computer-readable storage medium. The method, device, computer program, storage media and kit specifically may be used in medical diagnostics, for example, qualitatively or quantitatively detect analytes in body fluids, such as for detecting glucose in blood and/or interstitial fluid. Other fields of application of this disclosure, however, are feasible.
G01N 21/84 - Systems specially adapted for particular applications
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
This disclosure is directed to a disposal container system enabling storage of used or contaminated articles having a generally flat, strip-shaped configuration, such as diagnostic biosensors. The disposal container is removably mountable to a supply container, and has an insertion portion provided in a wall of the disposal container. The insertion portion has a contour configured externally to guide deposit of a flat, strip-shaped article through a narrow slit, the contour further configured internally to deflect any loose articles in the interior space of the disposal container away from any accidental alignment with the slit which would cause free extraction of the articles. The disposal container may be configured for engagement with a supply container, such as a round or non-round vial, in a bottom-cap configuration or in a side-by-side configuration, by way of an engagement portion.
A61B 50/36 - Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments for collecting or disposing of used articles
A method of performing an analytical measurement based on a color formation reaction in an optical test strip by using a mobile device having a camera. An optical test strip having a test field is provided. The camera captures a first image of at least part of the test field before a sample is applied and a second image after the sample is applied. The mobile device indicates where to take the second image so that the first and second images are taken at similar local positions with respect to at least one environmental feature that has a fixed and/or unchanged position between the capturing of the first and second images. An analytical measurement result value is then determined by using the first and second images. A computer program, a computer-readable storage medium, a mobile device and a kit for performing an analytical measurement are also disclosed.
G01N 21/84 - Systems specially adapted for particular applications
G01N 33/487 - Physical analysis of biological material of liquid biological material
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
42.
METHOD AND SYSTEM FOR ANALYZING GLUCOSE MONITORING DATA INDICATIVE OF A GLUCOSE LEVEL
A computer-implemented method and a system for analyzing glucose monitoring data indicative of a glucose level, comprising: presenting by a data processing device provided a graphical window on a display device wherein the graphical window comprises a time abscissa axis that defines time units, and a glucose ordinate axis that defines glucose units; receiving a plurality of glucose monitoring values associated with a monitoring time period by the data processing device; segmenting the plurality of glucose monitoring values into a plurality of glucose monitoring traces indicative of the glucose level; defining a reference trace segment; determining the reference trace segment for each of the plurality of glucose monitoring traces; and plotting, for a time window comprising the reference trace segment, the plurality of glucose monitoring traces within the graphical window. Furthermore, a non-transitory computer readable medium is disclosed.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A method for monitoring medical data is disclosed, the method being applicable to a system comprising a portable medical device, a mobile communications device, and, optionally, a medical care server. The portable medical device and the mobile communications device each comprise at least one interface for data transfer. The method comprises a step of establishing a download link between the mobile communications device and a download server. The method comprises a step of selecting an appropriate communication software package from a plurality of communication software packages for controlling data transfer between the mobile communications device and the portable medical device from the download server. Further, the method comprises a download step for downloading communication software package from the download server to the mobile communications device and a step of installation of the communication software package on the mobile communications device.
G06F 9/44 - Arrangements for executing specific programs
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
Embodiments related to a self-administered, behavior modification program facilitated through a structured tailoring method and system thereof which accelerates and enhances the internalization process of the individual, and which provides help when the individual begins to fail in adhering or continuing with the behavior modification are disclosed. Program instructions that when executed by a processor causes a processor to initiate automatically a schedule of events of a structured tailoring procedure upon entry criteria being met at some unknown time, provide intervention according to the intervention preferences when the adherence criteria for one of the events has not been met, and end automatically the structured collection procedure upon exit criteria being met at some unknown time.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
Disclosed is a cannula system having a rigid cannula, a cannula assembly and an insertion assembly. The rigid cannula is connected to the cannula assembly. The cannula assembly has a septum mounted to a mounting structure of the cannula assembly, a connecting structure for reversibly or irreversibly connecting the cannula assembly to a cannula assembly holder, a cavity being at least partially formed by the septum. The rigid cannula is in fluidic communication with the cavity. Furthermore, the insertion assembly has a rigid needle at least partially penetrating the septum and an attachment structure for reversibly attaching the insertion assembly to the cannula assembly.
A method is disclosed for determining concentration of an analyte in a body fluid with a mobile device having a camera. The camera captures an image of an optical test strip having a test field. The analyte concentration value is determined from color formation of the test field. Provided in the mobile device is a correlation for transforming color formation of the test field into analyte concentration. Also provided in the mobile device is an item of clearance information indicating a level of confidence for the correlation. When the item of clearance information indicates a sufficient level of confidence for the correlation, the mobile device indicates to a user that the capturing of the image does not require using a color reference card. Further disclosed are a method of controlling analytical measurements, a mobile device, a system for controlling analytical measurements and computer programs for performing and/or controlling analytical measurements.
A method of performing an analytical measurement based on a color formation reaction in an optical test strip by using a mobile device having a camera, a display and a position sensor. An optical test strip having a test field is provided. The camera captures a first image of the test field before a sample is applied and a second image after the sample is applied. An item of admissibility information, based on one or both of position sensor data and local position data, is determined. Admissibility is indicated when the position of the mobile device is substantially the same for capturing the first and the second image. When admissibility is indicated, an analytical measurement takes place. Further, a computer program, a computer-readable storage medium, a mobile device and a kit are disclosed.
G01N 21/84 - Systems specially adapted for particular applications
G01N 21/27 - Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 33/487 - Physical analysis of biological material of liquid biological material
48.
ZWITTERION BUFFER CONTAINING COMPOSITIONS AND USES IN ELECTROANALYTICAL DEVICES AND METHODS
Described herein are reagent compositions for detecting and/or measuring analytes in a test sample. In one embodiment, reagent compositions are described for detecting and/or measuring glucose in a sample.
C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
C12Q 1/54 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
C12Q 1/32 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
49.
ADJUSTMENT METHOD FOR AN ANALYTICAL DETERMINATION OF AN ANALYTE IN A BODY FLUID
A method for adjusting a measurement setup used in an analytical method. The method includes a plurality of users carrying out analyte measurements that involve capturing images of an optical test strip having a test field and obtaining training data. The training data is then used to identify similarities and to identify a plurality of user profiles according to the similarities. Then, profile-specific measurement setup adjustments for at least one of the user profiles are provided for the individual user profile. An analytical method, an adjustment system and a mobile device are also disclosed.
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
50.
AMBULATORY MEDICAL DEVICE AND METHOD FOR COMMUNICATION BETWEEN MEDICAL DEVICES
An ambulatory medical device and a method of communication between medical devices are disclosed. In one embodiment, the medical device includes a module for communication with at least a second medical device wherein the module for communication is adapted to be activated by a value of a physiological parameter of an animal. In one embodiment, the method of the present invention involves a first medical device and at least a second medical device wherein the communication between said medical devices is activated by a value of a physiological parameter of an animal.
Embodiments related to a system and method managing the implementation, execution, data collection, data analysis and status reporting of a structured collection procedure running on a portable, hand-held collection device are disclosed. The collection device performing the structured collection procedure has program instructions that when executed by a processor cause the processor to initiate automatically a schedule of events of the structured collection procedure upon one or more entry criteria being met at some unknown time, store in memory patient data collected in accordance to the schedule of events, end automatically the structured collection procedure upon one or more exit criteria being met at some unknown time. Status reporting can be provided throughout the execution of the collection procedure.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
Disclosed herein is a cradle for a medical device. The cradle has an inner cradle side and an opposing outer cradle side, wherein the outer cradle side is adapted for attachment to a patient's skin with at least part of the outer cradle side facing the patient's skin. The medical device has a medical device coupler, wherein the medical device coupler is adapted for coupling the medical device to the cradle such that part of the medical device is facing the inner cradle side. The cradle further includes a drain fluidly coupling the inner cradle side with the outer cradle side.
A method for operating a medical system includes providing a public-private key pair for asymmetric cryptography, wherein the public key is provided to remote control and medical devices, and the private key is provided to a security module, encrypting a control command with the public key in the remote control, receiving the encrypted control command in the security module, decrypting the encrypted control command with the private key, encrypting a security module control command with the private key applied to the decrypted control command or an amended medical control command derived from the decrypted control command, receiving the security module control command in the medical device, decrypting the security module control command with the public key, and controlling operation of the medical device according to the decrypted security module control command, if confirmed by a user confirmation input received in the security module or the medical device.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
H04L 9/30 - Public key, i.e. encryption algorithm being computationally infeasible to invert and users' encryption keys not requiring secrecy
54.
SYSTEM FOR BLOOD GLUCOSE METER COUPLED WITH MOBILE ELECTRONIC DEVICE
A hybrid analyte test meter includes a processor operatively connected to a memory, measurement signal generator, measurement signal receiver, and short range wireless transceiver. The processor executes firmware instructions in the memory to operate the measurement signal generator to apply electrical signals to a sample deposited on the electrochemical test strip via the port, receive signal measurements from the measurement signal receiver in response to the predetermined sequence of electrical signals, and transmit data corresponding to the plurality of signal measurements to an external computing device using the short range wireless transceiver, wherein the processor does not identify a measurement of an analyte in the sample based on the plurality of signal measurements.
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
H04B 5/00 - Near-field transmission systems, e.g. inductive loop type
H04B 5/02 - Near-field transmission systems, e.g. inductive loop type using transceiver
G06F 21/57 - Certifying or maintaining trusted computer platforms, e.g. secure boots or power-downs, version controls, system software checks, secure updates or assessing vulnerabilities
H04L 9/32 - Arrangements for secret or secure communications; Network security protocols including means for verifying the identity or authority of a user of the system
G01N 33/66 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
55.
STRUCTURED TESTING METHOD FOR DIAGNOSTIC OR THERAPY SUPPORT OF A PATIENT WITH A CHRONIC DISEASE AND DEVICES THEREOF
A structured testing method for diagnostic or therapy support of a patient with a chronic disease and devices thereof are disclosed which implement a structured collection procedure based on a medical use case and/or question which provides at least one or more parameters defining entry criterion, a schedule of events, adherence criterion, and exit criterion. The entry criterion establish conditions needed to be met prior to obtaining biomarker data from the patient. Each event can include one or more of a performance time, patient guidance to perform the event, a request for information from the patient a request for patient action, and a request for collection of biomarker data from the patient. The adherence criterion can be used to assess whether an event performed is acceptable to addressing the medical use case and/or question, and the exit criterion establishes conditions needed to be met prior to exiting the collection procedure.
G06F 16/21 - Design, administration or maintenance of databases
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 33/66 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
A holder for a medical device has a transcutaneously insertable portion and at least one housing. The holder has at least one mounting device that has a first side and an opposing second side. The mounting device also has a hole reaching from the first side to the second side. The mounting device is configured for being connected to the housing of the medical device. The holder also has two straps that are respectively attached to the mounting device and are fixedly connectable to each other.
The disclosure relates to a method and a system for a wireless data communication between a sensor system and a receiver capable of receiving analyte values sensed by the sensor system in a continuous analyte monitoring. The method includes establishing an unconnected mode operation for the system. The receiver receives a first data package broadcasted by the sensor system that has first status data indicative of a device status and/or an analyte value status. The first status data is processed by a receiver controller. A connected mode operation is established for the system responsive to determining at least one of a critical device status and a critical analyte value status. The establishing includes establishing a communication channel between the sensor system and the receiver and receiving a second data package transmitted by the sensor system in the receiver, the second data package comprising one or more analyte values.
H04L 41/0806 - Configuration setting for initial configuration or provisioning, e.g. plug-and-play
H04Q 9/00 - Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
H04W 76/15 - Setup of multiple wireless link connections
An inventive medical system includes a skin-mountable medical device, the skin-mountable medical device including an activatable tactile indicator. The medical system further includes a user interface configured to receive location information, the location information indicating a body location where the skin-mountable medical device shall be mounted. The medical system is configured to determine an active control pattern in dependence of the location information and to control activation of the tactile indicator in accordance with the active control pattern. Also disclosed are a remote control for use in combination with a skin-mountable medical device as well as methods for providing tactile indications to a user of a medical system.
A jacket for watertight sealing a medical device is disclosed. The jacket includes a flexible envelope having a first side and an opposing second side. The first side has a first sealing lip configured to surround the medical device and a second sealing lip spaced from the first sealing lip and configured to surround the medical device. The flexible envelope has an envelope contacting sealing end that is fixedly connectable to the opposing second side. A method of using the inventive jacket includes mounting a medical device on a skin site of an extremity of a user and placing the jacket onto the skin site such that the first sealing lip and the second sealing lip surround the medical device. The flexible envelope is then wrapped around the extremity and fixedly connects the envelope contacting sealing end to the opposing second side of the flexible envelope.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
Disclosed herein is a cannula system including a soft cannula 10 and a cannula holder for holding the soft cannula. The cannula holder has a compressor and a body. The body contains a mounting structure and a cavity for holding a septum. The soft cannula is threaded on the mounting structure. Furthermore, the compressor circumferentially surrounds the mounting structure and at least parts of the body. The compressor provides an internal material tension for exerting a compression force on the soft cannula and the mounting structure.
B29C 45/14 - Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
A method of determining concentration of an analyte in a body fluid using a mobile device having a camera is disclosed. In the inventive method, angular orientation of the mobile device relative to the test element is determined by using sensor data of a sensor integrated into the mobile device. The angular orientation of the mobile device relative to the test element is subjected to a validity test. Taking into account the result of the validity test, an image of at least part of a test strip is captured and concentration of analyte in a body fluid sample applied to the test strip can be determined.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
H04N 5/232 - Devices for controlling television cameras, e.g. remote control
63.
IMPLANTATION NEEDLE FOR INSERTING A SUBCUTANEOUSLY INSERTABLE ELEMENT INTO A BODY TISSUE
An implantation needle for inserting a subcutaneously insertable element into a body tissue, a kit for inserting a subcutaneously insertable element into a body tissue and a method of manufacturing an implantation needle are described. The implantation needle comprises at least one covering comprising at least one pharmaceutical compound. The pharmaceutical compound is configured to remain at least partially in the body tissue after insertion of the subcutaneously insertable element.
A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
64.
METHOD OF DETERMINING A CONCENTRATION OF AN ANALYTE IN A BODILY FLUID AND MOBILE DEVICE CONFIGURED FOR DETERMINING A CONCENTRATION OF AN ANALYTE IN A BODILY FLUID
A method of determining concentration of an analyte in a body fluid using a mobile device having a camera is disclosed. In the inventive method, the camera is used to take a series of calibration images of a region of interest of an object. The calibration images differ in their brightness. A key calibration figure is derived from each calibration image, the key calibration images being characteristic for a tone mapping function of the mobile device. A probable tone mapping function of the mobile device is determined by taking into account the key calibration figures. An analysis image is taken of at least part of a test field of an optical test strip, the test field having a body fluid applied thereto. Analyte concentration is determined from the analysis image of the test field by taking into account the probable tone mapping function of the mobile device.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/84 - Systems specially adapted for particular applications
G06T 7/80 - Analysis of captured images to determine intrinsic or extrinsic camera parameters, i.e. camera calibration
Embodiments of the present invention are directed to devices, systems and methods for delivering therapeutic fluid (e.g., insulin) into the body, including a skin adherable cradle, for retaining a therapeutic fluid dispenser for delivering a therapeutic fluid to a user.
Detection reagents, multi-analyte test elements, test systems, and multi-analyte measuring methods are provided. In particular, multi-analyte test elements have (1) a first working electrode and first counter electrode pair covered with a first analyte-specific reagent that includes an enzyme, a coenzyme and a first mediator and have (2) a second working electrode covered with a second analyte-specific reagent that includes an enzyme, a coenzyme and a second mediator, where the second mediator is different than the first mediator. The single counter electrode can be used as the counter electrode for both the first and second analyte measurements at their respective working electrodes. Moreover, the mediator concentrations, measurement ranges, and applied potential differences are not the same for each analyte-specific measurement.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
The present invention relates to a computer-implemented method for aiding in the guidance of diabetes drug therapy of an individual suffering from diabetes mellitus. The method is based on glucose data from said individual that are received at a processing unit, wherein said glucose data comprise at least three fasting glucose measurement values from said individual, and/or at least three matched pre-prandial glucose measurement values and postprandial glucose measurement values at the same meal from said individual. Further contemplated by the present invention is a device for aiding in the guidance of drug diabetes therapy of an individual suffering from diabetes, said device comprising a processing unit, and a computer program including computer-executable instructions, wherein said instructions, when executed by the processing unit, causes the processing unit to perform the computer-implemented method of the present invention.
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 20/70 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mental therapies, e.g. psychological therapy or autogenous training
A test strip eject mechanism for a fluid testing device comprising an actuation button and a lever having a distal end movably engaged with the button, the lever configured to rotate about a fulcrum, wherein the lever has a proximal end movably engaged with a sled which slides to transport the test strip, the device configured such that a user's insertion of a test strip onto the sled and in an insertion direction into the device causes the sled to contact the lever arm and the lever arm to contact and move the actuation button in an outward direction of the medical device and into a position where the actuation button can be actuated by the user.
This disclosure relates to a process for forming a membrane on an analyte sensor and further relates to an analyte sensor obtainable by this process. This disclosure also relates to a process for forming a sensing layer on an electrode of an analyte sensor and to an analyte sensor having the sensing layer obtainable by the inventive process as well as the membrane obtainable by the inventive process. The analyte sensors obtainable by the inventive processes may be used for conducting an analyte measurement of a body fluid of a user or a patient. This disclosure may be applied in the field of home care as well as in the field of professional care, such as in hospitals. Other applications are generally feasible.
An analyte measurement kit includes a sensor assembly having a transcutaneous sensor and a controller. The controller includes a battery that powers the sensor assembly and includes a magnetic sensor that generates an electrical activation signal in dependence of a magnetic field. The controller switches from a pre-operative state into an operative state upon generation of the activation signal. The sensor assembly releasably couples to an inserter. The inserter executes an insertion routine that advances the sensor assembly from a retracted position in which the transcutaneous sensor stands back behind a skin contact surface of the inserter into an advanced position in which the transcutaneous sensor projects beyond the skin contact surface, and subsequently decouples the inserter from the sensor assembly. The inserter includes an activation magnet. Executing the insertion routine changes the magnetic coupling between the activation magnet and the sensor assembly and thereby generates the activation signal.
An ambulatory medical device for attachment to a person's body includes a housing having a wall and a vibrator coupler. A convex outer surface of the vibrator coupler projects from the wall towards the outside of the housing. The vibrator coupler is coupled to the wall via a connector arranged along the circumference of the vibrator coupler. A vibrator mechanically vibrates upon activation. The vibrator is arranged at least partially inside a volume defined by the vibrator coupler and is mounted to the vibrator coupler. A skin attachment device is also disclosed. It has a substantially planar body having a skin attachment side and an opposing medical device mounting side. The skin attachment side includes a skin attachment structure for releasably attaching the skin attachment device to a person's skin and the medical device mounting side includes a medical device mount for releasably engaging with the ambulatory medical device.
An optical test strip (118) for measuring an analyte concentration in a sample of bodily fluid is disclosed. The optical test strip (118) comprises:
a) a bottom layer (116) having a first end (130);
b) a top layer (110) having a first end (132) essentially aligned with the first end (130) of the bottom layer (116);
c) at least one spacer layer (114) interposed between the bottom layer (116) and the top layer (110), the spacer layer (114) having a length shorter than the bottom layer (116) and shorter than the top layer (110) such that the top layer (110) and the bottom layer (116) protrude over the spacer layer (114), wherein the first end (130) of the bottom layer (116), the first end (132) of the top layer (110), and the spacer layer (114) form a sample receiving area (140) which at least partially has capillary properties for receiving the sample of bodily fluid; and
d) at least one test field (112), wherein the test field (112) comprises a test chemical being configured for performing an optically detectable detection reaction with the analyte, wherein the test field (112) comprises at least one first region (126) and at least one second region (128), wherein the first region (126) faces the sample receiving area (140), wherein the first region (126) is configured to be at least partly wetted by the sample of bodily fluid upon sample application, wherein the second region (128) is covered by the spacer layer (114) such that the second region (128) is essentially inaccessible for the sample of bodily fluid.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
Methods are provided for correcting an analyte concentration measurement that may be influenced by hematocrit (HCT), especially a glucose concentration measurement. The methods include determining by means of a reference instrument a HCT reference value of a reference blood sample taken from a specific user, applying a fresh blood sample of the user on a disposable analytical test element, measuring the glucose value of the fresh blood sample by single use of the test element in a glucose meter, determining a HCT correction value using at least the HCT reference value, and adjusting the measured glucose value using the HCT correction value to receive an adjusted glucose value. Also provided are devices and system incorporating or for performing the methods.
Disclosed is a cannula system having a soft cannula and a cannula unit for holding the soft cannula. The cannula unit includes a compressor and a body, and the body contains a mounting structure and a cavity for holding a septum. The soft cannula is threaded on the mounting structure. Furthermore, the compressor circumferentially surrounds the mounting structure and at least parts of the body. The compressor contains an internal material tension for exerting a compression force on the soft cannula and the mounting structure.
B29C 45/14 - Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
The present invention relates to a test element for the detection of an analyte comprising an enzyme, wherein the enzyme is incorporated in a nanocapsule.
G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
C08G 18/28 - Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
C12N 11/08 - Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
C12Q 1/32 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
C12Q 1/54 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
G01N 33/487 - Physical analysis of biological material of liquid biological material
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
The present invention relates to a method for detecting and in particular for measuring C-peptide. Specifically, the present invention relates to a displacement assay for quantitative determination of C-peptide in a sample.
A lock mechanism for a compartment has been developed. The lock mechanism includes a deformable arm affixed to a housing of the compartment and positioned within the compartment. The deformable arm includes a first end configured to be biased into a first position to engage a latch of a door of the compartment to prevent the latch from opening, and a receiving surface configured to receive an external force to move the deformable arm to a second position that disengages the first end from the latch to enable opening of the latch while the external force is applied to the receiving surface.
H01M 50/271 - Lids or covers for the racks or secondary casings
H01M 50/262 - Mountings; Secondary casings or frames; Racks, modules or packs; Suspension devices; Shock absorbers; Transport or carrying devices; Holders with fastening means, e.g. locks
Disclosed is a cradle for an infusion pump unit. The cradle has a proximal side and a distal side, and the distal side has an infusion pump unit attachment structure for attaching an initially separate infusion pump unit. The cradle includes a cradle base, a flow channel for a liquid drug, and a pierceable septum. The pierceable septum covers an opening of the flow channel and seals the flow channel. An inner piercing core of the pierceable septum is movably mounted with respect to the cradle base.
The application concerns a stickpack-type packaging comprising an elongate foil tube (12) having two transverse sealing joints (16,18), such that a tightly closed fill space (20) is provided in the foil tube (12) for storing a product. It is proposed that a single disposable test strip (22) is arranged in the fill space (20), wherein the test strip (22) has a chemistry pad (26) for detecting an analyte in a sample, and the chemistry pad (26) is arranged at a distance at least from one of the transverse sealing joints (16,18).
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
B65B 9/20 - Enclosing successive articles or quantities of material, in preformed tubular webs, or in webs formed into tubes around filling nozzles, e.g. extruded tubular webs the webs being formed into tubes in situ around the filling nozzles
B65B 61/02 - Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for perforating, scoring, or applying code or date marks on material prior to packaging
B65D 75/12 - Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks initially folded to form tubes with the ends of the tube closed by flattening and heat-sealing
B65D 75/44 - Individual packages cut from webs or tubes
B65D 75/58 - Opening or contents-removing devices added or incorporated during package manufacture
B65B 61/00 - Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
82.
Medical device alert, optimization, personalization, and escalation
An alert is used to inform a user that their blood glucose level has dropped below a threshold (e.g., the user is hypoglycemic) or has increased above a threshold (e.g., the user is hyperglycemic). There is a hierarchy of alerts from lowest priority to highest priority. The alert is communicated by a user device (e.g., a mobile device), which is, for example, a smartphone, smart watch, home automation device, or the like. The alert is modified in order to increase the likelihood that the user receives or acknowledges the alert within a minimal amount of time. An intensity level (e.g., a volume) of an alert is modified based on, for example, whether the user has acknowledged a previous alert. A modality or a sensory channel of an alert is changed if an initial alert does fails to elicit a response from the user.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G08B 3/10 - Audible signalling systems; Audible personal calling systems using electromagnetic transmission
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61B 5/1171 - Identification of persons based on the shapes or appearances of their bodies or parts thereof
A skin-mountable medical device having a mounting plate having a bottom side attachable to the skin of a user and a medical module, in particular, an analyte sensing device or a drug administration pump. A snap connector releasably attaches the medical module on the upper side of the mounting plate. The snap connector has a release flap that can be actuated by the user to detach the medical module, and the release flap projects outwardly from the mounting plate and at its bottom side maintains a clearance to avoid an interfering skin contact in use.
An optical test strip (110), a method and a kit (128) for measuring an analyte concentration in a sample (112) of bodily fluid are disclosed. The optical test strip (119) comprising:
a) a test strip carrier (114) having at least one transparent area (116);
b) a test field (118), wherein the test field (118):
comprises at least one carrier foil (120), wherein the carrier foil (120) is applied to the test strip carrier (114) and at least partially covers the transparent area (116) of the test strip carrier (114);
comprises at least one test chemical (122) applied to the carrier foil (120), the test chemical (122) being configured for performing an optically detectable detection reaction with the analyte, wherein the test chemical (122) is further configured for at least partially absorbing light having at least one absorption wavelength λabs (144) in the range 650 nm<λabs<1100 nm; and
comprises at least one porous material (124) for at least partially filtering out solid components contained in the sample (112);
wherein the carrier foil (120) has at least one wavelength filter component (121) which is adapted to essentially block light having wavelengths λblc (146) of λblc≤WLlow, with 550 nm≤WLlow≤650 nm.
G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
Disclosed is a pierceable septum for use in drug reservoirs and infusion sets. The pierceable septum has an elastic core made from a core material and a surround made from a surrounding material. The surrounding material is more rigid than the core material. The elastic core is fully embedded in the surround.
A61M 5/162 - Needle sets, i.e. connections by puncture between reservoir and tube
B29C 45/56 - Means for plasticising or homogenising the moulding material or forcing it into the mould using mould parts movable during or after injection, e.g. injection-compression moulding
B29C 45/17 - Component parts, details or accessories; Auxiliary operations
A61M 39/04 - Access sites having pierceable self-sealing members
86.
METHOD AND SYSTEM FOR DETERMINING CONCENTRATION OF AN ANALYTE IN A SAMPLE OF A BODILY FLUID, AND METHOD AND SYSTEM FOR GENERATING A SOFTWARE-IMPLEMENTED MODULE
A method for generating a module configured to determine concentration of an analyte in a sample of a body fluid is disclosed. The method includes providing a first set of measurement data derived from images of one or more test strips indicating a color transformation in response to a body fluid containing an analyte. The images can be recorded by multiple devices with differing cameras, software and/or hardware device configurations for image recording and image data processing. A neural network model can be generated in a machine learning process applying an artificial neural network and a module configured to determine concentration of an analyte in a second sample of a body fluid can be generated. Further, the present disclosure includes a system for generating the module as well as a method and a system for determining concentration of an analyte in a sample of a bodily fluid.
A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.
The present disclosure relates to a method for powering up a medical device powered by a battery. The method includes executing an initial battery test. In the initial battery test, a difference voltage between a battery voltage measured without and with a test load is determined. The test load is favorably dimensioned not to significantly stress the battery. The difference voltage is compared with a difference voltage threshold, the difference voltage threshold being predefined in dependence of the no-test-load voltage. The method further includes providing an alarm if the difference voltage is above the difference voltage threshold. The present disclosure further concerns a medical device that implements the method and a method for determining the relation between the difference voltage and the difference voltage threshold. The disclosure can be used to ensure that an alarm is provided if a newly inserted battery is too weak to power the medical device.
In one embodiment, a blood withdrawal system for withdrawing blood for diagnostic purposes includes a base device configured to hold a structurally distinct lancet. The base device includes an actuatable lancet ejection mechanism for ejecting the lancet from the base device, and the lancet ejection mechanism includes a movable coupling element. The coupling element includes a coupling structure for coupling the lancet with an external component via the coupling element and subsequently activating the lancet ejection mechanism by operating the external component.
Management of a diabetic condition may be performed by detecting a mealtime and/or an increased level of activity associated with a user. The mealtime is detected based one or more mealtime indicators that may indicate a likelihood of an occurrence of a mealtime. Each mealtime indicator provides additional context around the likelihood of a mealtime. To assist in managing the diabetic condition, a user's elevated activity levels may be detected. The activity level of a user is detected based on one or more activity indicators. Each activity indicator provides additional context around the likelihood of an increased level of activity by the user. Management of the diabetic condition may be performed proximate a mealtime or a user exercising to increase the efficacy of management of the diabetic condition.
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
H04W 4/029 - Location-based management or tracking services
G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
An implantation needle has an implantable element receiving portion, a capsule receiving portion, and a tip portion. The capsule receiving portion has a fixing element such as a mechanical barrier or an adhesive surface. A kit is also provided that includes the implantation needle with an implantable element disposed in the implantable element receiving portion and a capsule disposed in the capsule receiving portion. The instant disclosure also relates to a method for administering an implantable element and a capsule to a subject. The method includes inserting an implantation needle of the implantation kit into a tissue of a subject and discharging the implantable element and capsule into the patient's tissue.
A method of evaluating the suitability of a mobile device for performing an analytical measurement based on a color formation reaction. The capability of the mobile device to have relevant settings of the mobile device controlled by software running on the mobile device is evaluated. The relevant settings pertain to image raw data processing steps to be carried out by the mobile device and may include a color space transformation and a tone mapping transformation. When the evaluation indicates that the mobile device is capable of having the relevant settings controlled by the software, control information indicating that the mobile device is suitable for performing the analytical measurement is provided. When the evaluation indicates that the mobile device is not capable of having the relevant settings controlled by the software, control information indicating that the mobile device is unsuitable for performing the analytical measurement is provided.
H04N 17/00 - Diagnosis, testing or measuring for television systems or their details
G06T 7/80 - Analysis of captured images to determine intrinsic or extrinsic camera parameters, i.e. camera calibration
H04N 5/232 - Devices for controlling television cameras, e.g. remote control
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
94.
METHODS AND DEVICES FOR PERFORMING AN ANALYTICAL MEASUREMENT
A method of performing an analytical measurement based on a color formation reaction in an optical test strip using a mobile device having a camera. In the inventive method, an optical test strip having a test field is provided. A first image of at least part of the test field is captured using the camera with an image acquisition setting of the camera, and the image acquisition setting is locked. A sample of body fluid is applied to the test field and then there is a step of waiting a predetermined minimum amount of time. Then, while the image acquisition setting remains locked, a second image of at least part of the test field is captured using the camera with the same image acquisition setting of the camera used to capture the first image. An analytical measurement result value is then determined by using the first and the second images.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G06T 7/90 - Determination of colour characteristics
A method for analysing physiological measurement values of a user is proposed. The method comprises at least one data acquisition step, wherein, during the data acquisition step, physiological measurement values of the user are acquired at different measurement times and stored in a measurement data record; at least one pattern selection step, wherein, during the pattern selection step, measurement values acquired during one comparison time interval are selected as at least one comparison pattern; and at least one pattern recognition step, wherein, during the pattern recognition step, patterns corresponding to the comparison pattern are sought after in the measurement data record.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A resealable container including a housing, a lid coupled to the housing, and a basket received within the housing and including side walls defining an interior space, and a retainer extending over at least a portion of the interior space and configured to support at least one test element in at least one of a side-to-side direction and a front-to-back direction within the basket.
A system and method for considering the effects of aerobic exercise on blood glucose levels for individuals is described. In at least one embodiment of the system of the present disclosure, the system comprises a computing device for generating a prediction of future blood glucose levels for the individual at least partly based on an exercise model, wherein the exercise model is based on parameters that are independent of intensity of the aerobic exercise, and a means for taking an action at least based on the prediction from the exercise model.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G09B 19/00 - Teaching not covered by other main groups of this subclass
G09B 23/28 - Models for scientific, medical, or mathematical purposes, e.g. full-sized device for demonstration purposes for medicine
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
98.
Apparatus and method for battery passivation compensation in a medical device
A method for operating a medical device includes activating a processor in the medical device in a low-power operating mode, measuring a first voltage level of the battery, applying at least one discharge pulse to the battery in response to the first voltage level of the battery being greater than a predetermined passivation minimum voltage threshold and less than a predetermined passivation maximum voltage threshold, measuring a second voltage level of the battery after the at least one discharge pulse, and operating the processor in the medical device in an increased-power operating mode to continue operation of the medical device only in response to the second voltage level being greater than or equal to a predetermined operating voltage threshold, the predetermined operating voltage threshold being greater than the predetermined passivation minimum voltage threshold and less than or equal to the predetermined passivation maximum voltage threshold.
A cannula cartridge for receiving a cannula includes a needle assembly, a cannula and a protector. The needle assembly is movable within the protector between first and second positions. In the first position the needle is covered by the protector and a retainer of the protector engages an engagement element of the needle hub by a form fit connection. In the second position the needle at least partially extends from the protector. An inserter can move the needle assembly between the first position and to the second position and then back to the first position. The retainer and the engagement element are configured such that a holding force of the retainer is overcome by applying forces parallel to the axis of the needle. An inventive kit that includes an inserter and a driver for moving the needle assembly and a method of manufacturing the cannula cartridge are also disclosed.
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
An implantable medical device has an implantable power supply and an implantable medical unit. The implantable supply powers the device and it includes a hermetically sealed supply housing, a battery, and a supply power coupler that powers the implantable medical unit from the battery via a wireless coupling. The implantable medical device also has a hermetically sealed medical unit housing, and it includes a functional medical module including a continuous glucose meter module. In use, the implantable medical unit is releasably mechanically coupled to the implantable supply and a wireless coupling of a medical unit power coupler with a supply power coupler is made, thereby powering the medical unit from the battery of the implantable supply.
patents
