A photoresin formulation for volumetric additive manufacturing contains a photo- curable mixture of: a monomer (e.g., an acrylate-based monomer); a photoinitiator; a polymerization inhibitor (e.g., molecular oxygen (02)); and, a reducing agent reactive with a free radical species (e.g., a peroxyl radical) formed from the polymerization inhibitor. The reducing agent permits faster printing of objects from the photoresin formulation in a volumetric additive manufacturing process to produce 3D objects of high fidelity.
B33Y 30/00 - Appareils pour la fabrication additive; Leurs parties constitutives ou accessoires à cet effet
B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
B33Y 80/00 - Produits obtenus par fabrication additive
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
The present disclosure provides a non-destructive technique for the measurement of bearing element speed and/or pass-frequency (roller speed and/or pass- frequency for roller bearings or ball speed and/or pass-frequency for ball bearings) that can be compared with a rotational rate of the rotary element to evaluate skidding. The technique employs a high temperature optical emitter and detector pair, which may be adjacent in a reflective setup, or at opposite sides of the bearing in a pitch-catch setup. The emitter has an opening angle of 45-120 to enable the sensor to operate in an oil droplet laden environment. In either configuration, the sensors have been successfully demonstrated at speeds beyond 20,000 rpm and oil supply temperatures up to 82 C, and have been demonstrated on roller bearings featuring metallic and polymer-based cages. The sensors are also not sensitive to bearing material and can achieve results with metal as well as hybrid bearings (e.g. ceramic rollers).
The present invention concerns new strains of cyanogenic bacteria, and more particularly alkali-tolerant Pseudomonas bacteria, that are useful to gold mining activities. These bacteria are useful to leach gold from any source including ores and concentrates. They have the ability to effectively produce cyanide at alkaline pH.
C12P 3/00 - Préparation d'éléments ou de composés inorganiques à l'exception du dioxyde de carbone
C22B 3/18 - Extraction de composés métalliques par voie humide à partir de minerais ou de concentrés à l'aide de micro-organismes ou d'enzymes, p.ex. de bactéries ou d'algues
An electrochemical device is disclosed, which may include an anode, a cathode, and a molded electrolyte composition disposed between the anode and the cathode. Implementations of the electrochemical device may include where the cathode and/or the anode are disposed in a stacked geomety. The electrolyte composition may include a gel polymer electrolyte, which can include a hydrogel of a copolymer and a salt dispersed in the hydrogel of a copolymer. The electrolyte composition may alternatively include a crosslinker or a photoinitiator. A method of producing an electrolyte layer of an electrochemical device is also disclosed, including preparing a substrate having an electrode for an electrochemical device, preparing a gasket to form a cavity on the substrate for the electrolyte layer, and depositing an electrolyte composition onto the substrate
H01M 6/18 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Éléments primaires; Leur fabrication Éléments avec électrolytes non aqueux avec électrolyte solide
A composite material suitable for use in sensing and catalysis applications with conjugated polymers non-covalently bound to the carbon nanotubes. The conjugated polymers have alternating aromatic (Ar) units and bipyridine (BPy) units. Metal nanoparticles having a size that is between about 0.3 nm and about 5 nm are bound to the conjugated polymers at respective BPy units, thereby anchoring the metal nanoparticles to the carbon nanotubes. Thus, a metal salt solution was added into the polymer/carbon nanotube solution to fonn a metal- BPy complex, which is in situ photo reduced to metal nanoparticles. Therefore, the fomied nanoparticles are tightly anchored to the nanotube and can be self-regenerated by room light to offer the material a high performance and durability.
C08L 79/04 - Polycondensats possédant des hétérocycles contenant de l'azote dans la chaîne principale; Polyhydrazides; Polyamide-acides ou précurseurs similaires de polyimides
C01B 32/174 - Dérivatisation; Solubilisation dans les solvants; Dispersion dans les solvants
B01J 20/20 - Compositions absorbantes ou adsorbantes solides ou compositions facilitant la filtration; Absorbants ou adsorbants pour la chromatographie; Procédés pour leur préparation, régénération ou réactivation contenant une substance inorganique contenant du carbone obtenu par des procédés de carbonisation
C08K 7/24 - Particules expansibles, poreuses ou creuses inorganiques
C08L 65/00 - Compositions contenant des composés macromoléculaires obtenus par des réactions créant une liaison carbone-carbone dans la chaîne principale; Compositions contenant des dérivés de tels polymères
A biodegradable solid aqueous electrolyte composition, an electrochemical device incorporating the electrolyte composition, and methods for the same are provided. The electrolyte composition may include a rubber-like hydrogel including a copolymer and a salt. The copolymer may include at least two polycaprolactone chains coupled with a polymeric center block. The polymeric center block may include polyvinyl alcohol. The hydrogel may be biodegradable. The electrochemical device may include an anode, a cathode, and the electrolyte composition disposed between the anode and the cathode.
C08L 29/04 - Alcool polyvinylique; Homopolymères ou copolymères d'esters partiellement hydrolysés d'alcools non saturés avec des acides carboxyliques saturés
C08L 67/04 - Polyesters dérivés des acides hydroxycarboxyliques, p.ex. lactones
H01M 6/18 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Éléments primaires; Leur fabrication Éléments avec électrolytes non aqueux avec électrolyte solide
Disclosed are devices with dynamic optical properties suitable for use as security or authentication devices, for example for documents or items of importance or value, in order to help prevent counterfeit of the same. Such devices, at least in selected embodiments, enable observation of dynamic changes or moving entities within the device by collective imaging of the dynamic changes or moveable entities, the motion or position of which may otherwise be difficult to observe, or indiscernible to, the naked eye.
A forming tool with forced thermal fluid-based spatio-temporal temperature control of a surface of the tool has a subsurface manifold underlying at least a part of a forming surface of the tool and a number P of at least 6 ports, each port fluid coupled respectively to the manifold via respective channels, where the ports exit the tool at disparate points, with each pair of ports in fluid communication via the manifold. This structure allows manifold path diversity for varying thermal fluid supply and drainage. The manifold may be reinforced.
Here is disclosed isolated or purified monoclonal antibodies, or an antigen-binding fragments thereof, which binds to human CD3, and which comprises: a CDRH1 amino acid sequence of SEQ ID NO: 150, a CDRH2 amino acid sequence of SEQ ID NO: 151, a CDRH3 amino acid sequence of SEQ ID NO: 152, a CDRL1 amino acid sequence of SEQ ID NO: 153, a CDRL2 amino acid sequence of SEQ ID NO: 154, and a CDRL3 amino acid sequence of SEQ ID NO: 155. Also provided are recombinant polypeptides comprising said monoclonal antibody, or an antigen-binding fragment thereof, such as multivalent antibodies, including bispecific T-cell engagers. Also described are chimeric antigen receptors (CARs) for CAR-T therapy comprising any one of the monoclonal antibodies, or antigen-binding fragments thereof. Nucleic acids encoding the aforementioned antibodies, fragments, and polypeptides are also disclosed, along with therapeutic applications in the treatment of and autoinflammatory disease or cancer.
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
C07K 14/705 - Récepteurs; Antigènes de surface cellulaire; Déterminants de surface cellulaire
10.
ANTI-BCMA SINGLE DOMAIN ANTIBODIES AND THERAPEUTIC CONSTRUCTS
Herein are provided anti-BCMA single domain antibodies (sdAb) prepared byte immunizing a llama with the ecto-domain of human B-cell maturation antigen (BCMA) that is preferentially expressed by mature B lymphocytes. By constructing a library of the heavy chain repertoire generated, VHH antibodies specific to the immunogen were isolated. The 13 unique example antibodies initially produced comprise CDR1, CDR2, and CDR3 sequences corresponding, respectively to SEQ NOs: 1-3, 4-6, 7-9, 10-12, 13-15, 16-18, 19-21, 22-24, 25-27, 28-30, 31-33, 34-36, 37-39; and related sequences. Also provided are multivalent antibodies comprising any one of the sdAbs, including bispecific T-cell engagers, bispecific killer cell engagers (BiKEs), and trispecific killer cell engagers (TriKEs). Also described are chimeric antigen receptors (CARs) for CAR-T therapy comprising any one of the aforementioned sdAbs. Uses of these molecules in the treatment of cancer or autoimmune diseases are also described, in particular hematological malignancies, such as multiple myeloma.
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
A61K 35/12 - Substances provenant de mammifères; Compositions comprenant des tissus ou des cellules non spécifiés; Compositions comprenant des cellules souches non embryonnaires; Cellules génétiquement modifiées
Antigen-binding agents such as humanized antibodies or antigen-binding fragments thereof, that specifically bind to epidermal growth factor receptor variant III (EGFRvIII) are provided. The EGFRvIII-specific humanized antibodies or antigen-binding fragments thereof may be used for the treatment of cancer.
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such compounds or pharmaceutical compositions.
A61K 51/10 - Anticorps ou immunoglobulines; Leurs fragments
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions.
A61K 51/10 - Anticorps ou immunoglobulines; Leurs fragments
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
A system and method are provided for optical beamforming and interferometry using digital source modulation. In one aspect, a digitally-modulated calibration signal is included in the optical target source, for use by receiving mirrors and equipment to continuously lock onto, track, and remove atmospheric and instrumental temporal distortion effects. By using this digitally-modulated calibration signal throughout the optical signal chain any variations that both it and the science/payload signal undergo can be removed, leading to lower cost optical mirrors and optical interferometers, as well as allowing for larger optical apertures
Provided are methods, expression systems, kits, and vectors for constitutive and/or cumate-inducible expression of a gene of interest in CHO cells. The expression systems and methods described herein employ CHO cells that are stably transfected with a nucleic acid molecule encoding a reverse cumate transactivator (rcTA), the expression of which is regulated by a cymene repressor (CymR), for constitutive and/or cumate-inducible expression of a gene of interest.
C12N 15/85 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes eucaryotes pour cellules animales
C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p.ex. cellules transformées par des virus
C12N 15/10 - Procédés pour l'isolement, la préparation ou la purification d'ADN ou d'ARN
C12N 15/12 - Gènes codant pour des protéines animales
C12N 15/63 - Introduction de matériel génétique étranger utilisant des vecteurs; Vecteurs; Utilisation d'hôtes pour ceux-ci; Régulation de l'expression
C12N 15/87 - Introduction de matériel génétique étranger utilisant des procédés non prévus ailleurs, p.ex. co-transformation
C12P 21/00 - Préparation de peptides ou de protéines
A coupler for coupling an RF connector to an ultrasound sensing element. The coupler includes a conductive coupler body with a first end and a second end. The first end includes a pad retaining recess with a compressible conductive pad positioned in and protruding from the pad retaining recess. The second end either includes an opening for receiving a male pin of a radio frequency (RF) connector or is shaped to be press-fitted into the female pin opening of an RF connector, to conductively connect the pin with the coupler body. A sensor connector is also disclosed.
H01R 13/631 - Moyens additionnels pour faciliter l'engagement ou la séparation des pièces de couplage, p.ex. moyens pour aligner ou guider, leviers, pression de gaz pour l'engagement uniquement
H01R 24/40 - Dispositifs de couplage en deux pièces, ou l'une des pièces qui coopèrent dans ces dispositifs, caractérisés par leur structure générale ayant des contacts disposés concentriquement ou coaxialement spécialement adaptés à la haute fréquence
G01D 11/00 - MESURE NON SPÉCIALEMENT ADAPTÉE À UNE VARIABLE PARTICULIÈRE; DISPOSITIONS NON COUVERTES PAR UNE SEULE DES AUTRES SOUS-CLASSES POUR MESURER PLUSIEURS VARIABLES; APPAREILS COMPTEURS À TARIFS; DISPOSITIONS POUR LE TRANSFERT OU LA TRANSDUCTION DE MESURE NON SPÉCIALEMENT ADAPTÉES À UNE VARIABLE PARTICULIÈRE; MESURES OU TESTS NON PRÉVUS AILLEURS - Parties constitutives des dispositions pour la mesure qui ne sont pas spécialement adaptées à une variable particulière
H01R 13/646 - CONNEXIONS CONDUCTRICES DE L'ÉLECTRICITÉ; ASSOCIATION STRUCTURELLE DE PLUSIEURS ÉLÉMENTS DE CONNEXION ÉLECTRIQUE ISOLÉS LES UNS DES AUTRES; DISPOSITIFS DE COUPLAGE; COLLECTEURS DE COURANT - Détails de dispositifs de couplage des types couverts par les groupes ou spécialement adaptés à la haute fréquence, p.ex. structures procurant une adaptation d'impédance ou un accord de phase
17.
METHODS AND SYSTEMS FOR LEARNING ONLINE TO PREDICT TIME-SERIES DATA
The present invention relates to methods and systems for learning online to predict time- series data. More specifically, the present invention discloses a system that takes at least one time-varying signal as input, and use a model with an adjustable set of parameters to predict the future values of this time-varying signal as output. The system maintains a compressed representation of the history of its predicted output values, and a learning rule is used to compute an update to the system's parameters so as to reduce any discrepancy between the current value of the time varying signal and all previous predictions for this value that are stored in the compressed representation. The system is operated to perform at least one robotic control, pattern classification, signal processing, or data generation task that is improved by predicting the future values of a time-varying input signal.
G06V 10/82 - Dispositions pour la reconnaissance ou la compréhension d’images ou de vidéos utilisant la reconnaissance de formes ou l’apprentissage automatique utilisant les réseaux neuronaux
18.
SINGLE CHIRALITY SC-SWCNT AND USES THEREOF IN PHOTO-ACTIVE DEVICES
A composition for use in a photo-active device has: a charge transfer network of single walled carbon nanotubes (SWCNT) having at least 95 wt% of semiconducting single walled carbon nanotubes (sc-SWCNT) based on total weight of the SWCNT, the sc-SWCNT containing at least 30 wt% of one chiral type of sc-SWCNT based on total weight of the sc-SWCNT; and, a solution processible electron trapping material of a fullerene compound, the electron trapping material in contact with the charge transfer network of SWCNT. The composition is readily prepared from solution processible components and is highly sensitive in a narrow wavelength band. The composition is particularly useful in photoconductors and phototransistors that operate on the infrared region of the electromagnetic spectrum.
H01L 29/16 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, mis à part les matériaux de dopage ou autres impuretés, seulement des éléments du groupe IV de la classification périodique, sous forme non combinée
19.
REFRACTORY LANCE ASSEMBLY AND REFRACTORY LANCE TUBE
Described are various embodiments of a refractory lance assembly and a composite refractory lance. In one embodiment, a refractory lance assembly is provided that comprises: an immersion tube having an immersion tip immersible within a melt and an extension tube coupled at an opposed end thereof to form a longitudinally extended composite tube therewith defining an optical path therein, wherein said longitudinally extended composite tube is injectable, in use, with an inert gas to form and probe an immersed melt surface. The assembly further comprises a shroud longitudinally encasing the composite tube and injectable with inert gas to mitigate fluid contamination of the composite tube and immersed melt surface.
The present application provides two dimensional benzo[4,5]imidazo[2,1-a]isoindole incorporated non-fullerene electron acceptors having the structure of Formula I (I), and processes for the synthesis and manufacture thereof. Also provided are semiconductor materials, polymers, oligomers, films and membranes incorporating the non-fullerene acceptor of Formula (I), and the optoelectronic devices made therefrom.
C07D 495/22 - Composés hétérocycliques contenant dans le système condensé au moins un hétérocycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle dans lesquels le système condensé contient au moins quatre hétérocycles
C08G 61/12 - Composés macromoléculaires contenant d'autres atomes que le carbone dans la chaîne principale de la macromolécule
21.
PERMANENT MAGNETS WITH INTEGRATED PHASE CHANGE MATERIALS
A permanent magnet (PM) for use in an electric machine including at least one cavity containing a phase change material (PCM) integrated with said PM, the PCM having a phase transition temperature between about 80°C to about 200°C, and preferably a latent heat of at least 50 kJ/kg, wherein in PM, each cavity is a blind, elongated chamber extending from one side of the PM, having two smaller dimensions and a larger dimension of each cavity is oriented substantially in a same direction, wherein the PM is composed of a hard magnetic phase, a binder phase and PM having an ultimate tensile strength of at least 150 Megapascal (MPa), wherein PM is mounted on a rotor of an electric machine and is formed by cold spray additive manufacturing (CSAM)
H01F 41/02 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants
A digital clean-up oscillator and associated method are provided for cleaning jitter from a noisy clock signal, comprising receiving a reference clock oscillator signal and the noisy clock signal to be cleaned; measuring the frequency of the reference clock signal in the time domain of the noisy clock signal; filtering any frequency variations from the measured frequency of the reference clock signal on timescales shorter than a phase change interval Tau_clean over which jitter in the noisy clock signal is to be cleaned; generating a phase increment signal DDS_pinc based on the measured and filtered frequency of the reference clock signal; clocking the phase increment signal DDS_pinc with the reference clock signal for generating an output digital phase ramp signal ?_DDS(t) that tracks the frequency of the noisy clock signal with phase wander removed on timescales less than the phase change interval Tau_clean; and converting the output digital phase ramp signal ?_DDS(t) to an output jitter-cleaned time domain clock signal frequency locked to the noisy clock signal.
Described herein are antibodies that specifically recognize the SARS-CoV-2 spike (S) polypeptide,compositions comprising said antibodies, uses thereof, and methods employing said antibodies. Eachantibody specifically recognizes the S1-RBD domain, S1-NTD domain, or S2 subunit of the SARS-CoV-2 spike polypeptide. Some antibodies are cross-reactive with variants of SARS-CoV-2 and othercoronavirus spike polypeptides, such as SARS-CoV S, pangolin CoV S, bat SARS-like CoV S, andcivet SARS-CoV S.
C07K 16/10 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de virus de virus à ARN
A61K 47/68 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. les supports ou les additifs inertes; Agents de ciblage ou de modification chimiquement liés à l’ingrédient actif l’ingrédient non actif étant chimiquement lié à l’ingrédient actif, p.ex. conjugués polymère-médicament l’ingrédient non actif étant un agent de modification l’agent de modification étant un anticorps, une immunoglobuline ou son fragment, p.ex. un fragment Fc
A61P 31/14 - Antiviraux pour le traitement des virus ARN
Described herein are antibodies that specifically recognize the SARS-CoV-2 spike (S) polypeptide, compositions comprising said antibodies, uses thereof, and methods employing said antibodies. Each antibody specifically recognizes the Sl-RBD domain, Sl-NTD domain, or S2 domain of the SARS-CoV-2 spike polypeptide. Some antibodies are cross-reactive with other coronavirus spike polypeptides, such as SARS-CoV S, pangolin CoV S, bat SARS-like CoV S, and civet SARS-CoV S.
A centrifugal microfluidic technique for heat treating emulsion-divided independent reaction volumes (IRVs) within a centrifugal microfluidic chip, and displacing the emulsion into a monolayer presentation chamber (pc) for imaging. A deep treatment chamber (tc) is provided for the heat treatment, a nozzle having a hydrodynamic radius for forming the IRVs is provided for injecting a sample for the IRVs into the tc filled with a dense immiscible medium. The tc is adjacent a heat controlled element for collectively heat treating the IRVs within the tc, where the IRVs form a 3d packing arrangement. The tc is coupled to a presentation chamber (pc) by an opening through which the IRVs can be selectively displaced without collapsing. The pc is adjacent a window transparent to a wavelength for inspecting the pc.
DPEP-1 binding agents, including antibodies, and pharmaceutical compositions containing the same are described. Also provided are methods for using and manufacturing such binding agents, antibodies and pharmaceutical compositions, as well as methods of their use for treating or preventing a disorder in a human subject in need thereof.
A pseudo-reference electrode comprising a pseudo-reference glass material backed by a silver conductor comprising silver metal, wherein the pseudo-reference glass material is a chalcogenide glass comprising a silver chalcogenide Ag2Ch, wherein Ch denotes a chalcogen, or a halide glass comprising a silver halide and at least one glass-forming oxide of a metal or a metalloid, a mixture of two or more of these glasses, or a composite of at least one of these glasses. This pseudo-reference electrode can be used in ion-selective electrode (ISE) sensors and ion-selective field effect transistors (ISFETs).
Herein are provided anti-EGFR single domain antibodies (sdAb) prepared by immunizing a llama with recombinant human EGFRvIII. VHH antibodies specific to EGFR were isolated. The example antibodies initially produced comprise CDR1, CDR2, and CDR3 sequences corresponding, respectively to SEQ NOs: 1-3, 4-6, 7-9, 10-12, 13-15, 16-18, 19-21, 22-24, 25-27, 28-30, 31-33, 34-36, 37-39, 40-42, 43-45, and 46-48; and related sequences, including humanized variants. Also provided are multivalent antibodies comprising any one of the sdAbs, including bispecific T-cell engagers, bispecific killer cell engagers (BiKEs), and trispecific killer cell engagers (TriKEs). Also described are chimeric antigen receptors (CARs) for CAR-T therapy comprising any one of the aforementioned sdAbs. Uses of these molecules in the treatment of cancer are also described, in particularly EGFR-high cancers. Hinge lengths may be selected to achieve desired activities, such as high activity or high selectivity for target vs. non-target cells.
C07K 16/28 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
C07K 14/705 - Récepteurs; Antigènes de surface cellulaire; Déterminants de surface cellulaire
C07K 16/30 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des récepteurs, des antigènes de surface cellulaire ou des déterminants de surface cellulaire provenant de cellules de tumeurs
A computer-implemented method for detecting attribute value pairs from corpus data using a computer comprising a processor and a computer readable medium comprising instructions executable by the processor to at least: receive the corpus data comprising at least one pair; detect a layout template of the at least one pair; measure the merit of the layout template by determining at least one of (a) relative magnitudes of content probabilities based on a probability of the contents of an attribute cell and a probability of a corresponding value cell, (b) the validity of a name-value pair, or (c) the pointwise mutual information of a frequency matrix M corresponding to a sparse vector capturing context information of a word; and output detected attribute value pairs.
G06F 17/00 - TRAITEMENT ÉLECTRIQUE DE DONNÉES NUMÉRIQUES Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des fonctions spécifiques
G06F 16/20 - Recherche d’informations; Structures de bases de données à cet effet; Structures de systèmes de fichiers à cet effet de données structurées, p.ex. de données relationnelles
G06F 16/28 - Bases de données caractérisées par leurs modèles, p.ex. des modèles relationnels ou objet
G06F 17/18 - Opérations mathématiques complexes pour l'évaluation de données statistiques
30.
BIODEGRADABLE ELECTROCHEMICAL DEVICE WITH BARRIER LAYER
An electrochemical device is disclosed and may include an electrolyte composition disposed between the anode and the cathode and a water vapor barrier which may include a biodegradable material, where the water vapor barrier is disposed to prevent water vapor escaping from the electrochemical device. The water vapor barrier further may include polylactic acid or a metalized coating. The water vapor barrier further may further include multiple layers and have a water vapor transmission rate (WVTR) less than or equal to 2 wt % over 24 hours. Embodiments of the water vapor barrier may also include a polymeric biodegradable material or a metalized coating disposed onto the biodegradable material. The water vapor barrier may also include multiple layers and may have a water vapor transmission rate (WVTR) less than or equal to 1 mg per cm2 over 24 hours.
B32B 27/32 - Produits stratifiés composés essentiellement de résine synthétique comprenant des polyoléfines
H01M 50/103 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par leur forme ou leur structure physique prismatique ou rectangulaire
H01M 50/122 - Matériau composite constitué d’un mélange de matériaux organiques et inorganiques
H01M 50/124 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par le matériau ayant une structure en couches
H01M 50/126 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par le matériau ayant une structure en couches comprenant au moins trois couches
H01M 50/128 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par le matériau ayant une structure en couches comprenant au moins trois couches dont au moins deux couches de matériaux inorganiques uniquement
H01M 50/129 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie caractérisés par le matériau ayant une structure en couches comprenant au moins trois couches dont au moins deux couches de matériaux organiques uniquement
H01M 50/141 - Boîtiers, fourreaux ou enveloppes primaires d’une seule cellule ou d’une seule batterie pour protéger contre les dommages causés par des facteurs externes pour protéger contre l’humidité
31.
PIEZOELECTRIC COMPOSITES COMPRISING CARBON NANOMATERIALS AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions that are extrudable and comprise a plurality of piezoelectric particles and a plurality of carbon nanomaterials dispersed in at least a portion of a polymer material. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer material. The polymer material may comprise at least one thermoplastic polymer, optionally further containing at least one polymer precursor. The compositions may define an extrudable material that is a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
B33Y 80/00 - Produits obtenus par fabrication additive
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux
B29C 64/165 - Procédés de fabrication additive utilisant une combinaison de matériaux solides et liquides, p.ex. une poudre avec liaison sélective par liant liquide, catalyseur, inhibiteur ou absorbeur d’énergie
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
32.
PIEZOELECTRIC COMPOSITES COMPRISING PIEZOELECTRIC PARTICLES COMPATIBILIZED WITH A POLYMER MATERIAL AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer material comprising at least one thermoplastic polymer, at least one polymer precursor, or any combination thereof, and a plurality of piezoelectric particles dispersed in at least a portion of the polymer material. The piezoelectric particles may interact non-covalently with at least a portion of the polymer material, be covalently bonded to at least a portion of the polymer material, and/or be reactive with at least a portion of the polymer material. The compositions may be extrudable and formable into a self-standing three-dimensional structure upon being extruded. Additive manufacturing processes may comprise forming a printed part by depositing the compositions layer-by-layer.
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
33.
PIEZOELECTRIC COMPOSITES CONTAINING A SACRIFICIAL MATERIAL AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles dispersed in a continuous polymer matrix comprising a first polymer material and a sacrificial material that are immiscible with each other. The sacrificial material, which may comprise a second polymer material, may be removable from the first polymer material under specified conditions. The piezoelectric particles may remain substantially non-agglomerated when combined with the continuous polymer matrix. The continuous polymer matrix may be treated to remove the sacrificial material to introduce a plurality of pores. The compositions may have a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes may comprise forming a printed part by depositing the compositions layer-by-layer.
B29C 64/112 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des gouttelettes individuelles, p.ex. de buses de jet
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
34.
PIEZOELECTRIC COMPOSITES HAVING IMMISCIBLE POLYMER MATERIALS AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer matrix comprising a first polymer material and a second polymer material that are immiscible with each other, and a plurality of piezoelectric particles located in at least a portion of the polymer matrix. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer matrix. The compositions may define an extrudable material that is a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
35.
THERMALLY CURABLE PIEZOELECTRIC COMPOSITES AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles and a polymer material comprising at least one thermoplastic polymer and at least one thermally curable polymer precursor. At a sufficient temperature, the at least one thermally curable polymer precursor may undergo a reaction, optionally also undergoing a reaction with the piezoelectric particles, and form an at least partially cured printed part. The piezoelectric particles may be mixed with the polymer material and remain substantially non-agglomerated when combined with the polymer material. The compositions may define a form factor such as a composite filament, a composite pellet, or an extrudable composite paste, which may be utilized in forming printed part by extrusion, layer-by-layer deposition, and thermal curing.
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
36.
POROUS PIEZOELECTRIC COMPOSITES AND PRODUCTION THEREOF
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles dispersed in at least a portion of a polymer matrix comprising first polymer material and a sacrificial material, the sacrificial material being removable from the polymer matrix to define a plurality of pores in the polymer matrix. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer matrix. The sacrificial material may comprise a second polymer material. The compositions may define a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes may comprise forming a printed part by depositing the compositions layer-by-layer and introducing porosity therein
B33Y 80/00 - Produits obtenus par fabrication additive
B29C 64/106 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux
B29C 64/165 - Procédés de fabrication additive utilisant une combinaison de matériaux solides et liquides, p.ex. une poudre avec liaison sélective par liant liquide, catalyseur, inhibiteur ou absorbeur d’énergie
B33Y 40/20 - Posttraitement, p.ex. durcissement, revêtement ou polissage
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
37.
PIEZOELECTRIC COMPOSITES FEATURING NON-COVALENT INTERACTIONS AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles non-covalently interacting with at least a portion of a polymer material via p-p bonding, hydrogen bonding, electrostatic interactions stronger than van der Waals interactions, or any combination thereof. The piezoelectric particles may be dispersed in the polymer material and remain substantially non-agglomerated when combined with the polymer material. The polymer material may comprise at least one thermoplastic polymer, optionally further including a polymer precursor. The compositions may define an extrudable material that is a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles and a polymer material comprising at least one thermoplastic polymer and at least one photocurable polymer precursor. The at least one photocurable polymer precursor may undergo a reaction in the presence of electromagnetic radiation, optionally undergoing a reaction with the piezoelectric particles, in the course of forming the printed part. The piezoelectric particles may be mixed with the polymer material and remain substantially non-agglomerated when combined with the polymer material. The compositions may define a form factor such as a composite filament, a composite pellet, or an extrudable composite paste, which may be utilized in forming printed parts by extrusion and layer-by-layer deposition, followed by curing.
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
B29C 64/165 - Procédés de fabrication additive utilisant une combinaison de matériaux solides et liquides, p.ex. une poudre avec liaison sélective par liant liquide, catalyseur, inhibiteur ou absorbeur d’énergie
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
39.
PIEZOELECTRIC COMPOSITES COMPRISING COVALENTLY BONDED PIEZOELECTRIC PARTICLES AND USE THEREOF IN ADDITIVE MANUFACTURING
Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer material comprising at least one thermoplastic polymer, and a plurality of piezoelectric covalently bonded to the at least one thermoplastic polymer and dispersed in at least a portion of the polymer material. The compositions are extrudable and may be pre-formed into a form factor suitable for extrusion. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.
B29C 64/118 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant un matériau filamentaire mis en fusion, p.ex. modélisation par dépôt de fil en fusion [FDM]
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
C08L 101/00 - Compositions contenant des composés macromoléculaires non spécifiés
The present invention provides a method and system to correctly sample, at a central location, a signal at a second clock frequency from a remote antenna when the signal is at a first clock frequency. The present invention provides an improved method of incoherent clocking to correctly sample a signal from a remote antenna at a clock frequency of a central location, such as a central site of a radio telescope array. The signal contains a "tracer" which is related to the frequency of the remote antenna. The tracer phase is written into a dual-port memory at the first clock frequency and then read from the memory at the second clock frequency. The tracer phase is transferred across digital clock domains using Gray-doe methods so that phase coding errors do not occur.
A system for the online sorting of ore samples based on mineralogy analysis includes a conveyor moving a stream of the ore samples along a conveying path, a LIBS module, a height measuring device, a focus controller and an airflow system. The LIBS module projects a LIBS laser beam along an optical path focused on an analysis spot of dimensions of the order of one or a few mineral components of the ore samples, and collects a returning LIBS light signal. The height measuring device and focus controller collaborate to adjust in real-time the focus of the LIBS laser beam to move the analysis spot perpendicularly to the conveyor according to a height of the ore samples crossing the optical path. The air flow system moves particles away from the optical path. A processing unit performs the mineralogy analysis of the ore sample based on the LIBS light signal.
G01N 21/71 - Systèmes dans lesquels le matériau analysé est excité de façon à ce qu'il émette de la lumière ou qu'il produise un changement de la longueur d'onde de la lumière incidente excité thermiquement
B07B 13/14 - Classement ou triage des matériaux solides par voie sèche non prévu ailleurs; Triage autrement que par des dispositifs commandés indirectement - Parties constitutives ou accessoires
Centrifugal microfluidic fractionation is facilitated by off-chip pressurized fluid control applied at ports of a centrifugal microfluidic chip during centrifugation. The off-chip control is leveraged to align a desired fraction of the fractionated sample in a column on the chip to an extraction channel for greater precision extraction. Higher density or lower density media can be used to displace the fractionated sample axis-proximally or axis-distally, respectively. Automation by pixel-based strobed imaging of the chip with image analysis can reduce human intervention in fractionation assaying.
The present invention relates, in general, to polypeptides capable of neutralizing SARS-CoV-2 and providing ACE2 enzymatic activity, and uses of these polypeptides for treating disorders related coronaviral infections (COVID-19) and the accompanying acute respiratory distress syndrome (ARDS) and major organ injuries, and methods of making such molecules.
The present disclosure relates to a single domain antibody that specifically binds to the epitope in the catalytic domain of carbonic anhydrase IX (CA-IX). The single domain antibody has a dissociation constant (KD) of 1 x 10-7 or lower for a monomeric form of human CA-IX and/or a dimeric form of human CA-IX.
Provided is an adjuvant composition comprising a glycoarchaeol and at least one immunostimulantselected from a Toll-like receptor (TLR) agonist and a saponin. The glycoarchaeol and/orimmunostimulant may be present as a pharmaceutically acceptable salt. The adjuvant compositionmay be comprised together with an antigen in an immunogenic composition, such as a vaccinecomposition, which may be for use to induce an immune response in a subject. Further provided isuse of the immunogenic composition to induce an immune response in a subject, particularly animmune response that comprises both a cell-mediated response and a humoral response.
A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p.ex. par les adjuvants chimiques
The disclosure pertains to tightly regulated inducible expression systems useful for the inducible production of one or more RNAs or proteins of interest, including the production of biologics such as recombinant proteins, vaccines, or viral vectors. Also provided are cell lines and kits useful for the production of said RNAs or proteins, as well as methods for making said cell lines and methods for inducing production of said RNAs or proteins.
A system for forming an object having a three-dimensional structure, the system comprising: a container for providing a photo-curable material to be polymerized; a rotatable stage for supporting the container; a light source for providing light rays having at least one light pattern to be guided into the container via an optical assembly; a processing unit for determining the light source's degree of non-telecentricity, and determining an optimally pre-distorted set of the at least one light pattern based on at least the photo-curable material's refractive index; correcting at least one distortion of the light rays caused by refraction at the container interface and/or correcting at least one distortion of the light rays caused by non-telecentricity; and whereby the correction of the at least one distortion of the light rays is performed without altering the calibration of the optical assembly.
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
The present invention provides an efficient quantum memory for storing a quantum state of light, such as a photon, for a temporary period of time in a fibre-integrated optical cavity and then recall the quantum state of light and quantum information at a later time with a high probability of success. The present invention uses a nonlinear optical switching mechanism to modify at least one property of the quantum light, or cavity, to trap the quantum light in the optical cavity. Subsequent application of the nonlinear optical switching mechanism switches at least one property of the stored quantum light, or cavity, to release the quantum light from the optical cavity. The present invention also provides quasi-deterministic single-photon generation by temporal multiplexing of a photon pair source integrated within the cavity.
G11C 13/04 - Mémoires numériques caractérisées par l'utilisation d'éléments d'emmagasinage non couverts par les groupes , ou utilisant des éléments optiques
G06N 10/40 - Réalisations ou architectures physiques de processeurs ou de composants quantiques pour la manipulation de qubits, p.ex. couplage ou commande de qubit
G02B 6/10 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
The use of an unctuous sealing material (high viscosity liquid bordering on, or having, solid behavior at low shear forces) for sealing open pore, highly crushable suction cups allows for increased surface conformation for fast secure vacuum gripping, and maintenance of the pressure differential with lower energy in view of the seal.Furthermore, fast grasping is demonstrated if the unctuous sealing material protrudes from the lip.
B05D 5/10 - Procédés pour appliquer des liquides ou d'autres matériaux fluides aux surfaces pour obtenir des effets, finis ou des structures de surface particuliers pour obtenir une surface adhésive
B25J 15/06 - Têtes de préhension avec moyens de retenue magnétiques ou fonctionnant par succion
B66C 1/02 - Eléments ou dispositifs de prise de la charge adjoints aux mécanismes de levage, de descente ou de halage, ou adaptés pour être utilisés avec ces mécanismes et transmettant les efforts à des articles ou à des groupes d'articles par succion
F16B 47/00 - Ventouses pour accrochage; Moyens équivalents utilisant des adhésifs
50.
LOW SCATTERING LOSS HIGH TEMPERATURE STABLE FIBER BRAGG GRATING SENSOR BASED ON MICROPORE FORMATION AND METHOD FOR PRODUCING SAME
A method and apparatus for inscribing a high-temperature stable Bragg grating in an optical waveguide, comprising the steps of: providing the optical waveguide; providing electromagnetic radiation from an ultrashort pulse duration laser, wherein the wavelength of the electromagnetic radiation has a characteristic wavelength in the wavelength range from 150 nanometers (nm) to 2.0 micrometers (?m); providing cylindrical focusing optics; providing a diffractive optical element that when exposed to the focused ultrashort laser pulse, creates an interference pattern on the optical waveguide, wherein the irradiation step comprises irradiating a surface of the diffractive optical element with the focused electromagnetic radiation, the electromagnetic radiation incident on the optical waveguide, from the diffractive optical element, being sufficiently intensive to cause permanent (Type II) change in the index of refraction within multiple Bragg grating planes in the core of the optical waveguide resulting from at least one micropore.
There is provided a biosensor for detecting water contaminants. The biosensor has a microbial fuel cell compartment, having (i) at least one opening to allow water into and out of the microbial fuel cell compartment, (ii) an anode comprising electroactive microorganisms, and (iii) a cathode. The anode is electrically and physically separated from the cathode. The anode is anaerobic and comprises electroactive microorganisms. The cathode is aerobic. The biosensor has a storage compartment housing a biodegradable carbon source to supply the biodegradable carbon source to the electroactive microorganisms; an electric impedance load; an electric switch forming an intermittent connection between the microbial fuel cell compartment and the electric impedance load; an electric sensor; and a control system coupled to the electric switch and the electric sensor, receiving a measurement from the electric sensor, and outputting an indication signaling the presence or absence of the water contaminants based on the measurement.
A device and method of fabricating a device having a plurality of depletion-mode high-electron-mobility transistors (HEMTs) on a single wafer are disclosed. The method of fabrication involves providing semiconductor layers capable of sustaining a two-dimensional electron sheet to enable electrical current to flow through the HEMT, forming a series of trenches and fins in the semiconductor layers over an active area of the semiconductor layers on which a gate contact terminal is to be set down, the fins of respective HEMTs having different widths resulting in different voltage thresholds for the respective depletion-mode HEMTs.
H01L 21/18 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives les dispositifs présentant au moins une barrière de potentiel ou une barrière de surface, p.ex. une jonction PN, une région d'appauvrissement, ou une région de concentration de porteurs de charges les dispositifs ayant des corps semi-conducteurs comprenant des éléments du groupe IV de la classification périodique, ou des composés AIIIBV, avec ou sans impuretés, p.ex. des matériaux de dopage
H01L 29/778 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à deux dimensions, p.ex. transistors à effet de champ à haute mobilité électronique HEMT
53.
MONOLITHIC INTEGRATION OF ENHANCEMENT-MODE AND DEPLETION-MODE GALIUM NITRIDE HIGH ELECTRON MOBILITY TRANSISTORS
A device and method of fabricating a device having depletion-mode and enhancement-mode high-electron-mobility transistors (HEMTs) on a single wafer are disclosed. The method of fabrication involves providing semiconductor layers capable of sustaining a two-dimensional electron sheet to enable electrical current to flow through the HEMT, forming a series of trenches and fins in the semiconductor layers over an active area of the semiconductor layers on which a gate contact terminal is to be set down, the fins of respective HEMTs having different widths resulting in different voltage thresholds for the respective depletion-mode HEMTs.
H01L 21/77 - Fabrication ou traitement de dispositifs consistant en une pluralité de composants à l'état solide ou de circuits intégrés formés dans ou sur un substrat commun
H01L 29/778 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à deux dimensions, p.ex. transistors à effet de champ à haute mobilité électronique HEMT
54.
DNA CONSTRUCT FOR STABLY PRODUCING EMPTY CAPSIDS OF THE FOOT-AND-MOUTH DISEASE VIRUS IN MAMMALIAN CELLS; PROCESSES, USES, AND COMPOSITIONS THEREOF
INSTITUTO NACIONAL DE TECNOLOGIA AGROPECUARIA (Argentine)
NATIONAL RESEARCH COUNCIL OF CANADA (Canada)
Inventeur(s)
Mignaqui, Ana Clara
Wigodorovitz, Andres
Durocher, Yves
Abrégé
The present invention refers to methods and compositions for increasing the production of large amounts of empty capsids of the foot-and-mouth disease virus (FMDV) in a stable manner in mammalian cells by regulating the expression of FMDV 3C protease. The instant methods and compositions are based on the fact that a decreased expression of 3C protease results in a reduced cell toxicity and an increased synthesis of viral capsid proteins, as well as production of recombinant empty capsids. The invention provides recombinant plasmids that direct the expression of P1, 3C, and the use of said plasmids for producing new stable cell lines capable of generating high titers of FMDV empty capsids. The invention provides methods for regulating the expression of the FMDV 3C protease gene at a transcriptional and translational level in order to achieve the required process level of 3C protease for the selection process, as well as the production process.
A method and apparatus are provided for effecting an RFID-based finger input sensing system using a transmission line connected to at least two RFID tags, by analyzing a plurality of features relating to the number of spikes in the derivatives of the RSS, timing of maximum RSS and the spikes of the RSS derivatives, relative RSS magnitude between the at least two RFID tags, and increase/decrease trend of the RSS, thereby eliminating the need for calibration and training.
G06F 3/046 - Numériseurs, p.ex. pour des écrans ou des pavés tactiles, caractérisés par les moyens de transduction par des moyens électromagnétiques
G06F 3/0362 - Dispositifs de pointage déplacés ou positionnés par l'utilisateur; Leurs accessoires avec détection des translations ou des rotations unidimensionnelles [1D] d’une partie agissante du dispositif de pointage, p.ex. molettes de défilement, curseurs, boutons, rouleaux ou bandes
Cellulose particles treated with a bio-based surfactant can be compounded into a polymer composite having improved mechanical properties, such as tensile strength and/or tensile modulus. Treatment can be integrated into an industrial scale continuous cellulose particle production process, and the process provides one or more of reduced environmental impact, reduced energy consumption, reduced chemical consumption, reduced water consumption, reduced processing/operational cost, reduced capital investment, increased output, improved fiber dispersion in the polymer matrix and improved thermal degradation properties of the composite.
An example semiconductor device includes: a first layer comprising a first semiconductor material; a second layer comprising a second semiconductor material; and an interface region disposed between the first layer and the second layer and corresponding to an expected depletion region of an interface between the first semiconductor material and the second semiconductor material, the interface region comprising a gradation from the first semiconductor material to the second semiconductor material; and wherein the interface region is configured to reduce Shockley-Read-Hall recombination in the semiconductor device.
H01L 29/36 - Corps semi-conducteurs caractérisés par la concentration ou la distribution des impuretés
H01L 29/20 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIIIBV
H01L 31/0296 - Matériaux inorganiques comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIIBVI, p.ex. CdS, ZnS, HgCdTe
H01L 31/065 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails adaptés comme dispositifs de conversion photovoltaïque [PV] caractérisés par au moins une barrière de potentiel ou une barrière de surface les barrières de potentiel étant uniquement du type à bande interdite graduelle
58.
CORRUGATED BURIED HETEROSTRUCTURE LASER AND METHOD FOR FABRICATING THE SAME
There is provided a method for fabricating a corrugated buried heterostructure laser, including patterning a dielectric layer coating a substrate having a <0-11> direction to obtain a hollow corrugated structure. The hollow corrugated structure includes a central portion and regularly spaced-apart tabs laterally extending from the central portion and aligned with the <0-11> direction. The method also includes, in a single metal organic chemical vapour deposition run, forming an active region in the hollow corrugated structure to obtain the corrugated buried heterostructure laser. The single run combines selective area growth, p-dopant diffusion and etching techniques. There is also provided a corrugated buried heterostructure laser including a substrate having a <0-11> direction, a corrugated structure defined in the substrate and including a central portion and regularly spaced-apart tabs laterally extending from the central portion and aligned with the <0-11> direction, and an active region grown in the corrugated structure.
H01S 5/12 - Structure ou forme du résonateur optique le résonateur ayant une structure périodique, p.ex. dans des lasers à rétroaction répartie [lasers DFB]
H01S 5/32 - Structure ou forme de la région active; Matériaux pour la région active comprenant des jonctions PN, p.ex. hétérostructures ou doubles hétérostructures
59.
REALIZATION OF THE PASCAL FROM THE BOLTZMANN CONSTANT USING MASS COMPARISON OF ARTIFACTS IN VACUUM AND GAS
The present disclosure relates to methods and systems for realization of a reference pressure as well as calibration of devices under test. The techniques leverage the measurement of buoyancy artifacts under vacuum and pressure conditions, and the use of gas law equations and related variables to obtain low uncertainty reference values for pressure among others. The techniques can include measuring an absolute mass difference of buoyancy artifacts under vacuum; measuring effective masses of the buoyancy artifacts under a gas pressure condition, and determining an effective mass difference between the buoyancy artifacts; and determining a low-uncertainty pressure based on the absolute mass difference, effective mass difference, Boltzmann constant, volume difference, molecular weight of the gas at pressure, and temperature of the measurements.
G01L 21/02 - Indicateurs de vide ayant une chambre de compression dans laquelle le gaz dont on doit mesurer la pression est comprimé
G01G 17/04 - Appareils ou méthodes pour peser un produit ayant une forme ou des propriétés particulières pour peser des fluides, p.ex. des gaz, des produits pâteux
60.
ELECTRIC MACHINES WITH ENHANCED ELECTROMAGNETIC INTERACTION
An electrical machine, which may be a motor and/or a generator has a rotor mounted to rotate about an axis. A plurality of magnetic poles are spaced circumferentially around the rotor in the bore. The rotor comprises a shell shaped to provide a toroidal bore centered on the axis. A slit extends circumferentially around the rotor. The slit penetrates through the shell into the bore. The electrical machine also includes a stator that is supported in the bore by one or more supports extending through the slit of the rotor. The stator carries plural windings that are spaced apart around the bore.
H02K 1/16 - Noyaux statoriques à encoches pour enroulements
H02K 1/22 - Parties tournantes du circuit magnétique
H02K 5/20 - Enveloppes ou enceintes caractérisées par leur configuration, leur forme ou leur construction avec des canaux ou des conduits pour la circulation d'un agent de refroidissement
61.
BURIED HETEROSTRUCTURE SEMICONDUCTOR LASER AND METHOD OF MANUFACTURE
A heterostructure laser is provided comprising an epitaxially grown substrate of first dopant type, an active region and layer of second dopant type, a narrow mesa having less than 20% open area and a side wall slope of less than 85 degrees, wherein said narrow mesa is etched through the active region and layer of second dopant type using in-situ MOCVD, a plurality of current blocking layers, an overclad layer and a contact layer of second dopant type, and an isolation mesa incorporating the narrow mesa, wherein the isolation mesa is etched through the active region, layer of second dopant type and plurality of current blocking layers and wherein the plurality of current blocking layers is grown without exposure to oxygen.
H01S 5/32 - Structure ou forme de la région active; Matériaux pour la région active comprenant des jonctions PN, p.ex. hétérostructures ou doubles hétérostructures
H01L 21/205 - Dépôt de matériaux semi-conducteurs sur un substrat, p.ex. croissance épitaxiale en utilisant la réduction ou la décomposition d'un composé gazeux donnant un condensat solide, c. à d. un dépôt chimique
62.
ULTRASONIC STRUCTURAL HEALTH MONITORING DEVICE, SYSTEM AND METHOD
Described are various embodiments of an ultrasonic structural health monitoring device, system and method. In one embodiment, an ultrasonic structural health monitoring device is described to monitor a structure. The device comprises a bottom electrode disposable on the structure; a piezoelectric medium disposed on the bottom electrode; a top electrode disposed on the piezoelectric medium; an acoustic insulation layer; and a connector to bring electrical excitation for the piezoelectric medium and to collect a generated electric response therefrom representative of structural health.
The present disclosure is directed towards a formulation for piezoelectric materials. The formulation may be printed including 2D or 3D printing. The formulation contains ceramic particles, a sol-gel, a high boiling point solvent and a binder.
B29C 64/165 - Procédés de fabrication additive utilisant une combinaison de matériaux solides et liquides, p.ex. une poudre avec liaison sélective par liant liquide, catalyseur, inhibiteur ou absorbeur d’énergie
B33Y 70/10 - Composites de différents types de matériaux, p.ex. mélanges de céramiques et de polymères ou mélanges de métaux et de biomatériaux
C08L 29/04 - Alcool polyvinylique; Homopolymères ou copolymères d'esters partiellement hydrolysés d'alcools non saturés avec des acides carboxyliques saturés
C08L 33/02 - Homopolymères ou copolymères des acides; Leurs sels métalliques ou d'ammonium
64.
MESA AVALANCHE PHOTODIODE WITH SIDEWALL PASSIVATION
A mesa-type avalanche photodiode comprising a first mesa of n-type material, a second mesa having an active region, and a third mesa of p-type material, wherein the second mesa includes a p-type sidewall formed by Zn diffusion for suppressing sidewall leakage current.
H01L 31/107 - Dispositifs sensibles au rayonnement infrarouge, visible ou ultraviolet caractérisés par une seule barrière de potentiel ou de surface la barrière de potentiel fonctionnant en régime d'avalanche, p.ex. photodiode à avalanche
H01L 31/0352 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails caractérisés par leurs corps semi-conducteurs caractérisés par leur forme ou par les formes, les dimensions relatives ou la disposition des régions semi-conductrices
65.
LAMINATED ARMOR MATERIALS FOR ENHANCED BALLISTIC PROTECTION
The present disclosure relates to laminated armor materials for enhanced ballistic protection. In particular, the present disclosure relates to laminated armor materials comprising first and second armor materials and a laminated adhesive layer comprising nanomaterial fillers.
The present disclosure is directed to a composite material comprising a thermoplastic adhesive and nanotubes oriented in the in-plane orientation. In additional aspects, the disclosure includes a laminated armor material comprising the composite and armor materials.
Herein are provided anti-CD22 single domain antibodies (sdAb) prepared by immunizing a llama with the extracellular domain of the predominant human CD22 isoform. By constructing a library of the heavy chain repertoire generated, VHH antibodies specific to the immunogen were isolated. The 27 example antibodies initially produced comprise CDR1, CDR2, and CDR3 sequences corresponding, respectively to SEQNOs: 1-3, 4-6, 7-9, 10-12, 13-15, 16- 18, 19-21, 22-24, 25-27, 28-30, 31-33, 34-36, 37-39, 40-42, 43-45, 46-48, 49-51, 52-54, 55- 57, 58-60, 61-63, 64-66, 67-69, 70-72, 73-75, 75-78, and 79-81; and related sequences. Also provided are multivalent antibodies comprising any one of the sdAbs, including bispecific T-cell engagers, bispecific killer cell engagers (BiKEs), and trispecific killer cell engagers (TriKEs). Also described are chimeric antigen receptors (CARs) for CAR-T therapy comprising any one of the aforementioned sdAbs. Uses of these molecules in the treatment of cancer are also described.
C07K 16/22 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des facteurs de croissance
A61K 35/17 - Lymphocytes; Lymphocytes B; Lymphocytes T; Cellules tueuses naturelles; Lymphocytes activés par un interféron ou une cytokine
A61P 35/02 - Agents anticancéreux spécifiques pour le traitement de la leucémie
A61P 37/06 - Immunosuppresseurs, p.ex. médicaments pour le traitement du rejet de greffe
C07K 14/705 - Récepteurs; Antigènes de surface cellulaire; Déterminants de surface cellulaire
68.
COATED SUBSTRATES AND METHODS FOR THE PREPARATION THEREOF
The present application relates to methods of preparing a coated substrate and coated substrates which can be optionally prepared from such methods. The methods comprise depositing on the substrate a single abrasion resistant layer by magnetron sputtering or depositing on the substrate a dual layer comprising a first abrasion resistant layer deposited by magnetron sputtering and a second abrasion resistant layer deposited by plasma-enhanced chemical vapor deposition.
C23C 14/06 - Revêtement par évaporation sous vide, pulvérisation cathodique ou implantation d'ions du matériau composant le revêtement caractérisé par le matériau de revêtement
C23C 16/513 - Revêtement chimique par décomposition de composés gazeux, ne laissant pas de produits de réaction du matériau de la surface dans le revêtement, c. à d. procédés de dépôt chimique en phase vapeur (CVD) caractérisé par le procédé de revêtement au moyen de décharges électriques utilisant des jets de plasma
C23C 28/00 - Revêtement pour obtenir au moins deux couches superposées, soit par des procédés non prévus dans un seul des groupes principaux , soit par des combinaisons de procédés prévus dans les sous-classes et
69.
NARROW LINEWIDTH LASER WITH FLAT FREQUENCY MODULATION RESPONSE
A laser comprising a narrow linewidth, comprising: a grating along a laser cavity; a laser waveguide having a plurality of waveguide sections corresponding to a plurality of grating sections, each of the plurality of waveguide sections having a ridge/mesa width for detuning the grating in each of the plurality of grating sections; and a plurality of contact electrodes contacting each of the plurality of waveguide sections, the plurality of contact electrodes for applying a different current to each of the plurality of waveguide sections to enable active feedback noise suppression.
H01S 5/062 - Dispositions pour commander les paramètres de sortie du laser, p.ex. en agissant sur le milieu actif en faisant varier le potentiel des électrodes
H01S 5/0687 - Stabilisation de la fréquence du laser
An antenna device for performing off-chip light coupling comprising an array of radiating elements whose thickness is larger than ?/2, the radiating elements being chosen such that the length of the array is smaller than 10 ?, where ? is the wavelength of light in the material chosen for the radiating elements. An advantage of this method is that, unlike in conventional waveguide grating antenna, by reducing the number of the radiating elements in the array, the dependence of the off-chip emission angle on the wavelength of light can be greatly reduced. Another advantage is that by using thick radiating elements the antenna efficiency can be greatly enhanced, thereby compensating for the reduced efficiency occurring as a consequence of using only a small number of radiating elements in the array.
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
H01S 5/02251 - Découplage de lumière utilisant des fibres optiques
G02B 6/124 - Lentilles géodésiques ou réseaux intégrés
G02B 6/34 - Moyens de couplage optique utilisant des prismes ou des réseaux
An interface device for performing off-chip coupling in optical waveguides includes an optical waveguide core for propagating light of a particular wavelength or a plurality of wavelengths and an array of radiative elements configured to change the propagation direction of the light. The optical waveguide core is configured to control the effective refractive index of the propagation mode of the light. The device can thus serve as an optical antenna for coupling between a waveguide mode and a free-space propagating beam or a plurality of free-space propagating beams in an arrayed configuration.
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
H01S 5/02255 - Découplage de lumière utilisant des éléments de déviation de faisceaux lumineux
G02B 6/124 - Lentilles géodésiques ou réseaux intégrés
G02B 6/34 - Moyens de couplage optique utilisant des prismes ou des réseaux
A method of monitoring both liner wear and charge impact in an industrial mill uses a sensor mounted on an elongated element deployed through a shell into a liner of the mill. The elongated element wears at a same rate as the liner under conditions within the shell. Liner wear is related to a reduction in length of the elongated element as measured by travel time of an ultrasound wave, while location and strength of charge impact is related to change in amplitude of vibrations caused by the charge impact. Liner wear measurement can be improved by using shear ultrasound waves instead of conventional longitudinal ultrasound waves. A mill monitoring apparatus has a means for acquiring ultrasonic waves and audible sound waves using the same digitizer; a means for determining the angular position of the monitoring apparatus; and a means for supplying electric power to the apparatus.
SYNCRUDE CANADA LTD. IN TRUST FOR THE OWNERS OF THE SYNCRUDE PROJECT AS SUCH OWNERS EXIST NOW AND IN THE FUTURE (Canada)
Inventeur(s)
Harhira, Aissa
Paproski, Richard
El Haddad, Josette
Sabsabi, Mohamad
Blouin, Alain
Abrégé
A method of quantifying at least one property of interest of an oil sands ore sample is provided using a laser-induced breakdown spectroscopy (LIBS) method. The property of interest may include bitumen content, water content, particle size information, cation exchange capacity, methylene blue index, mineralogical content (e.g., quartz, total clay, and clay components), amorphous material content, total ash content, and connate water parameter (e.g., conductivity, chloride content, or alkalinity).
G01N 21/71 - Systèmes dans lesquels le matériau analysé est excité de façon à ce qu'il émette de la lumière ou qu'il produise un changement de la longueur d'onde de la lumière incidente excité thermiquement
74.
A METHOD FOR FABRICATING CONDUCTIVE YARNS AND FABRICS AT ROOM TEMPERATURE
A method of fabricating a conductive yarn comprising a plurality of filaments, the method comprising the steps of: (a) applying a reducing agent solution to the treated surface; and (b) applying a metal ion solution to the treated at least one of the plurality of filaments. The method comprising a further step of treating the surface of the at least one of the plurality of filaments with a hydrophilic agent before performing steps (a) and (b).
H01B 1/22 - Matériau conducteur dispersé dans un matériau organique non conducteur le matériau conducteur comportant des métaux ou des alliages
D06M 11/83 - Traitement des fibres, fils, filés, tissus ou des articles fibreux faits de ces matières, avec des substances inorganiques ou leurs complexes; Un tel traitement combiné avec un traitement mécanique, p.ex. mercerisage avec des composés libérant des métaux, p.ex. des métaux-carbonyles; Réduction de composés métalliques sur des textiles
H05K 3/10 - Appareils ou procédés pour la fabrication de circuits imprimés dans lesquels le matériau conducteur est appliqué au support isolant de manière à former le parcours conducteur recherché
75.
SYNCHRONOUS RECTIFICATION TO IMPROVE EFFICIENCY OF ELECTRICITY CONVERSION FOR HARVESTING ENERGY FROM LOW VOLTAGE SOURCES
A DC-DC converter for converting a low voltage DC input to a higher voltage DC output, the DC-DC converter comprising: an oscillator comprising a first relatively voltage sensitive and relatively low power transistor and a second relatively voltage insensitive and relatively high power transistor, the oscillator producing an AC signal from the low voltage DC input; a first transformer for converting the AC signal produced by the oscillator to a higher voltage AC signal; an autonomous, synchronous voltage-doubling rectification circuit for converting the higher voltage AC signal to the higher voltage DC output, wherein the autonomous, synchronous voltage-doubling rectification circuit comprises a second transformer, a first shunt switch and a second shunt switch; and wherein current through the second transformer controls the synchronous rectification.
H02M 3/335 - Transformation d'une puissance d'entrée en courant continu en une puissance de sortie en courant continu avec transformation intermédiaire en courant alternatif par convertisseurs statiques utilisant des tubes à décharge avec électrode de commande ou des dispositifs à semi-conducteurs avec électrodes de commande pour produire le courant alternatif intermédiaire utilisant des dispositifs du type triode ou transistor exigeant l'application continue d'un signal de commande utilisant uniquement des dispositifs à semi-conducteurs
76.
DEFORMABLE MIRROR SYSTEMS AND METHODS OF DETECTING DISCONNECTED ACTUATORS THEREIN
A deformable mirror system comprising: a deformable mirror surface; a plurality of actuators coupled to the mirror surface to deform the mirror surface; and a detector coupled to the actuators to detect, for each actuator, an output signal from a driver of the actuator; and a controller coupled to each of the plurality of actuators, wherein the controller is configured, for each actuator, to: add a test signal to an input signal to form a modified input signal; send the modified input signal to the actuator; receive an indication of the output signal from the driver; determine when a test signal portion of the output signal satisfies a threshold condition; and in response to the test signal portion satisfying the threshold condition, control a subset of adjacent actuators to execute a shutdown sequence.
A quantum communication method comprising: at a sender, preparing photons encoded in a single spatial, spectral, and temporal (SST) mode to form a quantum signal; and introducing the quantum signal into a quantum channel; at a receiver, a detector and filtering system optically processing the quantum signal and rejecting background noise photons in the quantum channel, and performing active temporal filtering by switching the polarization of the quantum signal without substantially adding noise; and wherein the active temporal filtering minimizes saturation of the detector.
B82Y 20/00 - Nano-optique, p.ex. optique quantique ou cristaux photoniques
H04B 10/25 - Dispositions spécifiques à la transmission par fibres
G02B 27/09 - Mise en forme du faisceau, p.ex. changement de la section transversale, non prévue ailleurs
G02B 27/28 - Systèmes ou appareils optiques non prévus dans aucun des groupes , pour polariser
G02F 1/035 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p.ex. commutation, ouverture de porte ou modulation; Optique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des céramiques ou des cristaux électro-optiques, p.ex. produisant un effet Pockels ou un effet Kerr dans une structure de guide d'ondes optique
78.
USE OF RESISTIN AS A TRIMERIZATION PARTNER FOR EXPRESSION OF TRIMERIC PROTEINS
Provided is a recombinant polypeptide comprising a resistin trimerization domain and a polypeptide of interest. Further provided is an expression vector encoding the recombinant polypeptide and a method of expressing the recombinant polypeptide. The polypeptide of interest may be a trimeric viral surface antigen or a portion thereof, such as the ectodomain of the SARS-CoV-2 spike protein. Further provided are compositions, such as immunogenic compositions and vaccines, comprising the recombinant polypeptide.
A method for detecting and identifying a remote gas, the method comprising the steps of: receiving a light wave associated with the remote gas; coupling the light wave into a single mode fibre; transmitting the light wave via the single mode fibre into a filter comprising a fibre-based tunable cavity; modulating the cavity length of the filter transmission window to cause a detected modulated signal that is proportional to the spectral feature; and processing the signal using a lock-in amplifier capable of low-pass filtering and out-of-frequency noise rejection.
G01J 3/433 - Spectrométrie par modulation; Spectrométrie par dérivation
G01N 21/31 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique
G01J 3/26 - Production du spectre; Monochromateurs en utilisant une réflexion multiple, p.ex. interféromètre de Fabry-Perot, filtre à interférences variables
Abstract An integrated optical sensor enables the detection and identification of one or more remote gases using a transmission filter that matches specific absorption features of a remote gas and is detected using a single photodetection element. The sensor comprises an integrated optical component that is characterized by its transmission spectrum which corresponds to absorption or emission features of a target gas over a defined spectral bandpass, and the ability to have a reversibly tunable transmission spectrum. The change in the optical power output from the sensor as the transmission spectrum is tuned is proportional to the optical depth of the target gas absorption lines when viewed with a background light source. The optical power output from the integrated optical component is therefore related to the absorption spectrum of the input light Physical properties of the sensor are tailored to produce a quasi- periodic transmission spectrum that results in a stronger signal contrast for a specific gas. The sensor is preferably a waveguide ring resonator with a free spectral range that matches the absorption spectrum of a gas over a finite spectral bandpass. Date Recue/Date Received 2020-05-20
G01N 21/25 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes
G01N 21/3504 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge pour l'analyse des gaz, p.ex. analyse de mélanges de gaz
G01N 21/359 - Couleur; Propriétés spectrales, c. à d. comparaison de l'effet du matériau sur la lumière pour plusieurs longueurs d'ondes ou plusieurs bandes de longueurs d'ondes différentes en recherchant l'effet relatif du matériau pour les longueurs d'ondes caractéristiques d'éléments ou de molécules spécifiques, p.ex. spectrométrie d'absorption atomique en utilisant la lumière infrarouge en utilisant la lumière de l'infrarouge proche
G01J 3/42 - Spectrométrie d'absorption; Spectrométrie à double faisceau; Spectrométrie par scintillement; Spectrométrie par réflexion
G02B 6/12 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage du type guide d'ondes optiques du genre à circuit intégré
81.
FIBER BRAGG GRATING SENSOR IN POLYMER-COATED ULTRA-THIN OPTICAL FIBERS AND METHOD FOR PRODUCING SAME
A method and apparatus for inscribing a Bragg grating in an optical waveguide, comprising: providing electromagnetic radiation from an ultrashort pulse duration laser, wherein the electromagnetic radiation has a pulse duration of less than or equal to 5 picoseconds, and wherein the wavelength of the electromagnetic radiation has a characteristic wavelength in the wavelength range from 150 nanometers (nm) to 2.0 microns (?m); providing cylindrical focusing optics corrected for spherical aberration; providing a diffractive optical element that when exposed to the focused ultrashort laser pulse, creates an interference pattern on the optical waveguide, wherein the irradiation step comprises irradiating a surface of the diffractive optical element with the focused electromagnetic radiation, the electromagnetic radiation incident on the optical waveguide, from the diffractive optical element, being sufficiently intense to cause the permanent change in the index of refraction in the core of the optical waveguide.
G02B 6/34 - Moyens de couplage optique utilisant des prismes ou des réseaux
G03F 1/26 - Masques à décalage de phase [PSM phase shift mask]; Substrats pour PSM; Leur préparation
G01D 5/32 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensible; Moyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminé; Transducteurs non spécialement adaptés à une variable particulière utilisant des moyens optiques, c. à d. utilisant de la lumière infrarouge, visible ou ultraviolette avec atténuation ou obturation complète ou partielle des rayons lumineux
A coated electrode assembly (CEA) comprising: i) a gas diffusion layer (GDE); and ii) a coating. The GDE comprises a gas diffusion layer (GDL) and a catalyst layer. The catalyst layer is disposed between the coating and the GDL. The catalyst layer comprises a hydrophobic polymer and/or an ionomeric polymer and the coating comprises a hydrophobic polymer and/or an ionomeric polymer. A method for making a CEA is provided. The CEA may have improved performance and stability compared to a membrane electrode assembly (MEA).
C25B 11/032 - PROCÉDÉS ÉLECTROLYTIQUES OU ÉLECTROPHORÉTIQUES POUR LA PRODUCTION DE COMPOSÉS ORGANIQUES OU MINÉRAUX, OU DE NON-MÉTAUX; APPAREILLAGES À CET EFFET Électrodes; Leur fabrication non prévue ailleurs caractérisées par la configuration ou la forme perforées ou foraminées Électrodes poreuses Électrodes à diffusion de gaz
C25B 11/051 - PROCÉDÉS ÉLECTROLYTIQUES OU ÉLECTROPHORÉTIQUES POUR LA PRODUCTION DE COMPOSÉS ORGANIQUES OU MINÉRAUX, OU DE NON-MÉTAUX; APPAREILLAGES À CET EFFET Électrodes; Leur fabrication non prévue ailleurs caractérisées par le matériau Électrodes comportant des électro-catalyseurs sur un substrat ou un support
H01M 4/86 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes inertes ayant une activité catalytique, p.ex. pour piles à combustible
83.
FULL CONTROL OF POLARISATION IN FIBRE DELIVERED LIGHT FOR HARSH ENVIRONMENTS
A method of transmitting information comprising the steps of: (a) transmitting at least one photon via a fibre; (b) characterizing the fibre by determining at least one depolarization loss caused by the fibre; and (c) compensating for polarization altering effects of the fibre; wherein a single photon source is used for delivery of individual polarized photons in harsh environments.
H04B 10/2569 - Dispositions spécifiques à la transmission par fibres pour réduire ou éliminer la distorsion ou la dispersion due à la dispersion modale de polarisation [PMD]
84.
IMPROVING THE BIO-CRUDE YIELDS, PROPERTIES AND PROCESSABILITY OF HYDROTHERMAL LIQUEFACTION FEEDSTOCKS USING YELLOW GREASE
An example system for co-liquefying feedstock and yellow grease includes: a feedstock container to contain a feedstock; a yellow grease container to contain a yellow grease; a hydrothermal liquefaction system configured to receive feedstock from the feedstock container and to receive yellow grease from the yellow grease container; the feedstock received by the hydrothermal liquefaction system and the yellow grease received by the hydrothermal liquefaction system to become a mixture; a controller connected to the feedstock container and the yellow grease container, the controller configured to control the amount of the feedstock supplied from the feedstock container to the hydrothermal liquefaction system, the controller further configured to control the amount of the yellow grease supplied from the yellow grease container to the hydrothermal liquefaction system to be between 10% to 50% of the mixture; and a collector configured to receive a bio-crude from the hydrothermal liquefaction system.
C10G 3/00 - Production de mélanges liquides d'hydrocarbures à partir de matières organiques contenant de l'oxygène, p.ex. huiles, acides gras
C10G 1/00 - Production de mélanges liquides d'hydrocarbures à partir de schiste bitumineux, de sable pétrolifère ou de matières carbonées solides non fusibles ou similaires, p.ex. bois, charbon
85.
RADIATION-HARD, TEMPERATURE TOLERANT, GAN HEMT DEVICES FOR RADIATION SENSING APPLICATIONS
A semiconductor high electron mobility transistor (HEMT)-based device configured to detect ionizing radiation, wherein the device comprises: a substrate; a nucleation layer formed on the substrate; a gallium nitride (GaN) buffer layer arranged on the nucleation layer; a GaN channel layer arranged on the GaN buffer layer; an aluminum nitride (AlN) spacer layer arranged on the GaN channel layer; a barrier layer arranged on the AlN spacer layer; a GaN cap layer arranged on the barrier layer; an electrically insulating silicon nitride (SiNx) passivation layer arranged on the GaN cap layer; a source, a drain and a gate, wherein the source and the drain are formed on the GaN cap layer; wherein charge carriers generated by the radiation in the underlying GaN layers are collected in the GaN channel layer and multiplied by impact ionization by a high electric field at the gate edge facing the drain contact.
G01T 1/24 - Mesure de l'intensité de radiation avec des détecteurs à semi-conducteurs
H01L 29/20 - Corps semi-conducteurs caractérisés par les matériaux dont ils sont constitués comprenant, à part les matériaux de dopage ou autres impuretés, uniquement des composés AIIIBV
H01L 29/778 - Transistors à effet de champ avec un canal à gaz de porteurs de charge à deux dimensions, p.ex. transistors à effet de champ à haute mobilité électronique HEMT
86.
WATER SOLUBLE FORMULATIONS CONTAINING CANNABINOIDS
The present disclosure relates to water-soluble formulations containing cannabinoids. In particular, the formulations comprise at least one isolated cannabinoid, cannabinoid oil or cannabinoid resin, and a solubilizing agent of Formula (I), where the group X is a residue of a hydrophobic moiety selected from sterols, tocopherols, and derivatives thereof, and the group Y is a residue of a hydrophilic moiety selected from polyalcohols, polyethers, and derivatives thereof. In preferred embodiments, the cannabinoid comprises cannabidiol (CBD) or ?9-tetrahydrocannabinol (THC) and the hydrophobic moiety is polyoxyethanyl-?-tocopheryl sebacate (TPS). In embodiments, the formulations comprise a carrier oil, such as a medium length triglyceride (MCT), and are dispersed in water in the form of micelles.
A61K 31/352 - Composés hétérocycliques ayant l'oxygène comme seul hétéro-atome d'un cycle, p.ex. fungichromine ayant des cycles à six chaînons avec un oxygène comme seul hétéro-atome d'un cycle condensés avec des carbocycles, p.ex. cannabinols, méthanthéline
A61K 47/14 - Esters d’acides carboxyliques, p.ex. acides gras monoglycérides, triglycérides à chaine moyenne, parabènes ou esters d’acide gras de PEG
C07C 39/23 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons polycycliques contenant des cycles aromatiques à six chaînons et d'autres cycles avec une insaturation autre que celle des cycles aromatiques
C07D 311/72 - Dérivés dihydro-3, 4 comportant en position 2 au moins un radical méthyle et en position 6 un atome d'oxygène, p.ex. tocophérols
The present disclosure relates, for example, to water-soluble formulations containing cannabinoids. In particular, the formulations comprise a cannabinoid resin or oil and a solubilizing agent of Formula (I):
A distributed inductance integrated field effect transistor (FET) structure, comprising a plurality of FETs. Each FET comprises a plurality of source regions, a gate region having a plurality of gate fingers extending from a gate bus bar, a drain region having a plurality of drain finger extending from a drain bus bar between the plurality of gate fingers, wherein the gate region controls current flow in a conductive channel between the drain region and source region. A first distributed inductor connects the gate regions of adjacent ones of the plurality of FETs; and a second distributed inductor connects the drain regions of adjacent ones of the plurality of FETs.
H01L 27/02 - Dispositifs consistant en une pluralité de composants semi-conducteurs ou d'autres composants à l'état solide formés dans ou sur un substrat commun comprenant des éléments de circuit passif intégrés avec au moins une barrière de potentiel ou une barrière de surface
An example short-wave infrared imaging device includes: a detector to detect light representing an object to be imaged, the detector comprising a semiconductor wafer divided into an array of detector cells; and an image processor coupled to the detector to generate image data based on the reflected light detected at the detector; and wherein each detector cell comprises: a detection region of the semiconductor wafer; a dopant doped into the wafer in a sub-cell pattern having at least two spaced apart doped regions, the dopant to generate a signal based on light received in the detection region of the detector cell; a metal contact joining the at least two doped regions; and a signal processing circuit coupled to the metal contact to transmit the signal to the image processor.
H01L 31/08 - Dispositifs à semi-conducteurs sensibles aux rayons infrarouges, à la lumière, au rayonnement électromagnétique d'ondes plus courtes, ou au rayonnement corpusculaire, et spécialement adaptés, soit comme convertisseurs de l'énergie dudit rayonnement e; Procédés ou appareils spécialement adaptés à la fabrication ou au traitement de ces dispositifs ou de leurs parties constitutives; Leurs détails dans lesquels le rayonnement commande le flux de courant à travers le dispositif, p.ex. photo-résistances
90.
POLYURETHANE COMPOSITIONS AND ELASTOMERS THEREFROM
There is provided an erosion protective polyurethane elastomer produced from a polyurethane composition with a polyisocyanate component and an isocyanate-reactive component. The polyisocyanate component has a first isocyanate-terminated prepolymer obtained from the reaction of a first polyol with 1,4-bis(isocyanatomethyl cyclohexane) (1,4-H6XDI) or with a mixture of 1,4-H6XDI and a second aliphatic diisocyanate, an aromatic diisocyanate, and/or an arylalkyl diisocyanate, with at least 50 wt.% of diisocyanate used to produce the prepolymer is aliphatic diisocyanate. The isocyanate-reactive component has at least two low molecular weight (Mw < 400 g/mol) diols and a second polyol with hydroxyl groups to react with the prepolymer to produce a polyurethane elastomer. The polyurethane composition having a molar ratio of NCO/OH in the range of 1.00 1.50; whereby said polyurethane composition is curable to produce an elastomer having a mechanical strength >20 MPa, an elongation at break >500%, a tensile set <30%, and hydrolytic stability.
C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
The present invention provides compositions and methods of inducing an immune response in a subject in need thereof, comprising administering to the subject an immunologically-effective amount of a live Salmonella Typhi vector, wherein the Salmonella Typhi vector has been engineered to express one or more antigens; an outer membrane folding protein Bam A or a fragment or variant thereof; and a lipid A deacylase PagL or a fragment or variant thereof, wherein the Salmonella Typhi vector is capable of delivering the antigen to a mucosal tissue via an outer membrane vesicle when administered to a subject.
An optical fiber transducer usable in environments of extreme operating temperature features a stationary support, a movable body displaceable back and forth relative thereto, and an optical fiber connected between the support and the movable body. The fiber has a Fiber Bragg Grating in an intermediate region thereof between the support and movable body. To accommodate varying coefficients of thermal expansion (CTEs) among these components, one or more tubes close circumferentially around the fiber. Each tube has a CTE that is greater than that of the fiber, and less than that of the constituent material of the support and movable body. The fiber is bonded to an interior of the tube(s), while an exterior of the tube(s) is bonded to the support and movable body.
G01D 5/32 - Moyens mécaniques pour le transfert de la grandeur de sortie d'un organe sensible; Moyens pour convertir la grandeur de sortie d'un organe sensible en une autre variable, lorsque la forme ou la nature de l'organe sensible n'imposent pas un moyen de conversion déterminé; Transducteurs non spécialement adaptés à une variable particulière utilisant des moyens optiques, c. à d. utilisant de la lumière infrarouge, visible ou ultraviolette avec atténuation ou obturation complète ou partielle des rayons lumineux
G01P 15/03 - Mesure de l'accélération; Mesure de la décélération; Mesure des chocs, c. à d. d'une variation brusque de l'accélération en ayant recours aux forces d'inertie en utilisant des moyens non électriques
G02B 6/00 - OPTIQUE ÉLÉMENTS, SYSTÈMES OU APPAREILS OPTIQUES - Détails de structure de dispositions comprenant des guides de lumière et d'autres éléments optiques, p.ex. des moyens de couplage
G02B 6/34 - Moyens de couplage optique utilisant des prismes ou des réseaux
G02B 7/00 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques
A valve assembly for resin transfer molding is provided. The valve assembly includes an inlet positioned to receive a fluid. The valve assembly additionally includes a valve shaft positioned to receive the fluid from the inlet. The valve assembly further includes an outlet positioned to receive the fluid from the inlet. The valve assembly also includes an injection port positioned to receive the fluid from the valve shaft. The valve assembly also includes a piston configured to move coaxially within the valve shaft, such that the fluid is delivered from the inlet to the outlet when the piston is in a first position, and the fluid is delivered from the inlet to the injection port when the piston is in a second position.
B29C 45/02 - Moulage par transfert, c. à d. en transférant par un piston le volume déterminé de matière à mouler d'une cavité de charge à une cavité de moulage
B29C 45/17 - Moulage par injection, c. à d. en forçant un volume déterminé de matière à mouler par une buse d'injection dans un moule fermé; Appareils à cet effet - Eléments constitutifs, détails ou accessoires; Opérations auxiliaires
F16K 3/26 - Robinets-vannes ou tiroirs, c. à d. dispositifs obturateurs dont l'élément de fermeture glisse le long d'un siège pour l'ouverture ou la fermeture à faces d'obturation en forme de surfaces de solides de révolution avec corps de tiroir cylindrique le passage du fluide se faisant par le corps du tiroir
F16K 3/30 - Robinets-vannes ou tiroirs, c. à d. dispositifs obturateurs dont l'élément de fermeture glisse le long d'un siège pour l'ouverture ou la fermeture - Détails
F16K 11/07 - Soupapes ou clapets à voies multiples, p.ex. clapets mélangeurs; Raccords de tuyauteries comportant de tels clapets ou soupapes; Aménagement d'obturateurs et de voies d'écoulement spécialement conçu pour mélanger les fluides dont toutes les faces d'obturation se déplacent comme un tout comportant uniquement des tiroirs à éléments de fermeture glissant linéairement à glissières cylindriques
F16K 29/00 - Dispositions pour le mouvement des corps de soupapes autre que celui d'ouverture ou de fermeture de la soupape, p.ex. pour le rodage, pour empêcher le gommage
94.
FROTH FLOTATION PROCESS FOR SEPARATION OF METAL SULFIDES USING HYDROPHOBICALLY MODIFIED POLYALKYLENEIMINES
The present application relates to froth flotation processes for separating a copper sulfide and a nickel sulfide from a material comprising the copper sulfide and the nickel sulfide. The processes comprise agitating an aqueous suspension comprising particles of the material and a collector that is a hydrophobically modified polyalkyleneimine, while introducing a gas, thereby floating the copper sulfide in a froth fraction and depressing the nickel sulfide in a tails fraction, then separating the froth fraction from the tails fraction.
A technique for detection of probes in a microfluidic flow-through chamber involves a plurality of interface pinning reaction vessel formed by micro- or nano-structured relief patterning of a substrate. The relief patterning increases a surface area locally, and defines a plurality of separated interface pinning reaction vessels. The marked detection protocol may be supplied on a single layer of a stacked microfluidic chip, or the chamber may constitute a whole layer. The chip may be designed to be driven mechanically, pneumatically, hydraulically, centrifugally or by capillary action. Each vessel allows for a high density of probes, an effective region for developer-type or fluorescence-based marking, and efficient readout. Suitable probe liquids can be self-limiting to fill one vessel. Suitable developer liquids avoid dye bleeding across vessels during washing.
The present application relates to compositions comprising a bioactive lipophilic compound, an oil and at least one solubilizing agent that is a compound of Formula (I), to emulsions comprising such compositions and to uses thereof. The present application also relates to methods of preparing such emulsions. The methods comprise heating such compositions to form a homogeneous melt and combining the homogeneous melt with water to obtain the emulsion. (Formula (I))
A23L 29/10 - Aliments ou produits alimentaires contenant des additifs; Leur préparation ou leur traitement contenant des émulsifiants
A23L 33/10 - Modification de la qualité nutritive des aliments; Produits diététiques; Leur préparation ou leur traitement en utilisant des additifs
A23D 7/005 - Compositions à base d'huiles ou de graisses comestibles, contenant une phase aqueuse, p.ex. margarines caractérisées par des ingrédients autres que des triglycérides d'acides gras
A23D 7/02 - Compositions à base d'huiles ou de graisses comestibles, contenant une phase aqueuse, p.ex. margarines caractérisées par leur production ou leur traitement
A61K 8/06 - Cosmétiques ou préparations similaires pour la toilette caractérisés par une forme physique particulière Émulsions Émulsions
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61K 8/92 - Huiles, graisses ou cires; Leurs dérivés, p.ex. produits d'hydrogénation
A61K 31/047 - Composés hydroxylés, p.ex. alcools; Leurs sels, p.ex. alcoolates ayant plusieurs groupes hydroxyle, p.ex. sorbitol
A61K 47/44 - Huiles, graisses ou cires couvertes par plus d’un des groupes ; Huiles, graisses ou cires naturelles ou naturelles modifiées, p.ex. huile de ricin, huile de ricin polyéthoxylée, cire de lignite, lignite, gomme-laque, colophane, cire d’abeille ou lanoline
C07C 50/28 - Quinones contenant des groupes dont les atomes d'oxygène sont liés par liaison simple à des atomes de carbone à structure quinoïde monocyclique
C07C 403/24 - Dérivés du cyclohexane ou d'un cyclohexène, comportant une chaîne latérale avec une partie non saturée d'au moins quatre atomes de carbone en ligne, ladite partie étant directement attachée aux cycles cyclohexane ou cyclohexène, p.ex. vitamine A, bêt ayant des chaînes latérales substituées par des cycles non aromatiques à six chaînons, p.ex. bêta-carotène
97.
QUANTUM TUNNELING DEVICES FOR GENERATION OF HARMONICS IN PASSIVE WIRELESS TAGS AND SENSORS
A tag detection system comprising a source for producing an interrogation signal having a first frequency; a harmonic radar tag comprising: an antenna structure; a tunneling junction electrically and integrally coupled to the antenna; and wherein the harmonic radar tag when stimulated by the interrogation signal having the first frequency, and the harmonic radar tag produces a response signal at a second frequency different from the first frequency.
G01S 13/74 - Systèmes utilisant la reradiation d'ondes radio, p.ex. du type radar secondaire; Systèmes analogues
G01S 7/03 - DÉTERMINATION DE LA DIRECTION PAR RADIO; RADIO-NAVIGATION; DÉTERMINATION DE LA DISTANCE OU DE LA VITESSE EN UTILISANT DES ONDES RADIO; LOCALISATION OU DÉTECTION DE LA PRÉSENCE EN UTILISANT LA RÉFLEXION OU LA RERADIATION D'ONDES RADIO; DISPOSITIONS ANALOGUES UTILISANT D'AUTRES ONDES - Détails des systèmes correspondant aux groupes , , de systèmes selon le groupe - Détails de sous-ensembles HF spécialement adaptés à ceux-ci, p.ex. communs à l'émetteur et au récepteur
98.
BURIED HETEROSTRUCTURE SEMICONDUCTOR OPTICAL AMPLIFIER AND METHOD FOR FABRICATING THE SAME
A method for fabricating a buried heterostructure semiconductor optical amplifier is provided. The method includes a step providing a patterned dielectric layer on a substrate, the patterned dielectric layer having openings to expose uncovered regions of the substrate. The method also includes, in a single metal organic chemical vapour deposition (MOCVD) run: etching the uncovered regions of the substrate to form angles at corresponding edges thereof and diffusing a p-dopant in the substrate to obtain a p-dopant distribution in a portion of the substrate; etching a portion of the p-dopant thereby defining a recess in the substrate and growing a n-blocking layer in the recess; sequentially growing, over a portion of the n-blocking layer, an active region, a p-overclad, a p-contact, and a p-metal contact; and growing a n-metal contact on a backside of the substrate. The single MOCVD run combines selective area growth, p-dopant diffusion and etching techniques.
H01L 21/04 - Fabrication ou traitement des dispositifs à semi-conducteurs ou de leurs parties constitutives les dispositifs présentant au moins une barrière de potentiel ou une barrière de surface, p.ex. une jonction PN, une région d'appauvrissement, ou une région de concentration de porteurs de charges
G02F 1/015 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p.ex. commutation, ouverture de porte ou modulation; Optique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur des éléments à semi-conducteurs ayant au moins une barrière de potentiel, p.ex. jonction PN, PIN
H01L 21/283 - Dépôt de matériaux conducteurs ou isolants pour les électrodes
H01L 21/302 - Traitement des corps semi-conducteurs en utilisant des procédés ou des appareils non couverts par les groupes pour changer leurs caractéristiques physiques de surface ou leur forme, p.ex. gravure, polissage, découpage
99.
VERTICALLY TAPERED SPOT SIZE CONVERTER AND METHOD FOR FABRICATING THE SAME
There is provided a method for fabricating a vertically tapered spot-size converter on a substrate, comprising: growing a waveguide core on the substrate; coating the waveguide core with a photoresist layer; placing a photomask having patterns at a negative focus offset point with respect to the photoresist layer, the patterns being defined by openings in the photomask, each opening having a cross-section comprising a region of constant width and at least one region of non-constant width, the non-constant width reducing in a direction extending away from the region of constant width; transferring the patterns of the photomask to the photoresist layer; providing the waveguide core with a vertically tapered profile, the vertically tapered profile being provided by the patterns of the photomask; growing a cladding layer over the waveguide core; and patterning and etching the cladding layer and the waveguide core, thereby defining the vertically tapered spot-size converter.
ABSTRACT A technique for improving cold spray deposition conditions for cold spray additive manufacture of parts involves providing an in-situ temperature feedback controller with a remote instantaneous temperature sensor supplying surface temperature measurements of the deposition surface, and a (preferably long pulse) laser for heating. Temperature feedback allows for control over deposition conditions yielding predictable deposition properties. 38 Date Recue/Date Received 2020-12-15
B05B 12/10 - Aménagements de commande de la distribution; Aménagements de réglage de l’aire de pulvérisation sensibles à l'état du liquide ou d'un autre matériau fluide expulsé, du milieu ambiant ou de la cible sensibles à la température ou à la viscosité du liquide ou d'un autre matériau fluide expulsé
B05B 15/00 - APPAREILLAGES DE PULVÉRISATION; APPAREILLAGES D'ATOMISATION; AJUTAGES OU BUSES - Parties constitutives des installations ou des appareillages de pulvérisation non prévus ailleurs; Accessoires
brevets
