THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Ng, Boon Khai
Dai, William Alexander
Abrégé
An electrode lead comprises an elongated lead body, at least one lead connector terminal affixed to the proximal end of the lead body, and an electrically insulative cuff body affixed to the distal end of the lead body. The cuff body is configured for being circumferentially disposed around a nerve. The cuff body comprises cutouts, slits, a wrinkled portion, a thin stretchable portion, and/or a serpentine strap, which increases that increase the expandability of the cuff body when disposed around the nerve. The electrode lead further comprises at least one electrode contact affixed to the cuff body, and at least one electrical conductor extending through the lead body between the at least one lead connector terminal and the electrode contact(s). If the cuff body comprises cutouts or slits, the electrode lead can further comprise a thin stretchable film affixed to the cuff body over cutouts or slits.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Hotlani, Hitesh
Abrégé
An implantable medical device and a method of deduplicating data collected by the implantable medical device are provided. The method includes storing data, captured by the implantable medical device, in a non-volatile memory device of the implantable medical device, assigning a unique number, generated from a random number generator or counter, to each data block of the data, and deduplicating the data by deleting at least one of two or more data blocks that are associated with the same unique number.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Hotlani, Hitesh
Abrégé
An implantable medical device and a method of deduplicating data collected by the implantable medical device are provided. The method includes storing data, captured by the implantable medical device, in a non-volatile memory device of the implantable medical device, assigning a unique number, generated from a random number generator or counter, to each data block of the data, and deduplicating the data by deleting at least one of two or more data blocks that are associated with the same unique number.
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients
A61N 1/02 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet - Parties constitutives
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
4.
ELECTRODE LEADS HAVING MULTI-APPLICATION HELICAL NERVE CUFFS AND ASSOCIATED SYSTEMS AND METHODS
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Brandt, William Andrew
Dearden, Brian Ralph
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative helical cuff body configured to be disposed around a nerve, and a plurality of electrically conductive contacts carried by the helical cuff body that are spaced from one another.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian R.
Suri, Harshit
Lee, Edward K. F.
Abrégé
In accordance with the present invention, various embodiments of neurostimulators and stimulation systems are disclosed that provide different shapes and patterns of stimulus pulses and trains of pulses with fixed and no fixed frequencies. The neurostimulator can be configured to provide high frequency stimulation and also be implantable in the head or neck regions in order to stimulate nerves and nerve ganglions in the head and neck regions and also stimulate the brain.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/02 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet - Parties constitutives
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
6.
IMPLANTABLE MEDICAL DEVICE HAVING AN INERTIAL SENSING UNIT
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Shelton, Brian
Mech, Brian
Elyahoodayan, Sahar
Abrégé
A stimulation system configured to be implanted in a patient includes an implantable pulse generator (IPG) and an implantable lead system. The IPG includes a processor, a memory device, a power supply, and an inertial sensing unit configured to measure one or more physiological indicators of the patient. The implantable lead system includes at least one electrical lead coupled to the power supply and at least one electrode at a distal end of the electrical lead. The memory device includes instructions that cause the IPG to receive the physiological indicators within an initial range; increase the initial range to an enlarged range in response to the physiological indicators crossing a threshold maximum value or a threshold minimum value of the initial range; receive the physiological signals within the enlarged range, analyze the physiological indicators, and deliver stimulation to the patient through the electrode in response to the physiological indicators.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
7.
IMPLANTABLE MEDICAL DEVICE HAVING AN INERTIAL SENSING UNIT
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian
Mech, Brian
Elyahoodayan, Sahar
Abrégé
A stimulation system configured to be implanted in a patient includes an implantable pulse generator (IPG) and an implantable lead system. The IPG includes a processor, a memory device, a power supply, and an inertial sensing unit configured to measure one or more physiological indicators of the patient. The implantable lead system includes at least one electrical lead coupled to the power supply and at least one electrode at a distal end of the electrical lead. The memory device includes instructions that cause the IPG to receive the physiological indicators within an initial range; increase the initial range to an enlarged range in response to the physiological indicators crossing a threshold maximum value or a threshold minimum value of the initial range; receive the physiological signals within the enlarged range, analyze the physiological indicators, and deliver stimulation to the patient through the electrode in response to the physiological indicators.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p.ex. par le potentiel cardiaque
8.
TISSUE STIMULATION APPARATUS AND METHODS OF MAKING THE SAME
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Jenney, Christopher, Reed
Talbot, Neil
Calderon, Joseph
Elyahoodayan, Sahar
Brandt, William, Andrew
Abrégé
A method of forming a nerve cuff by combining a plurality of electrically conductive members with respective rear surfaces and grit blasted front surfaces with a nerve cuff body, which includes a respective plurality of windows, in such a manner that exposed portions of the grit blasted front surfaces are within the windows.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
9.
TISSUE STIMULATION APPARATUS AND METHODS OF MAKING THE SAME
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Jenney, Christopher Reed
Talbot, Neil
Calderon, Joseph L.
Elyahoodayan, Sahar
Brandt, William Andrew
Abrégé
A method of forming a nerve cuff by combining a plurality of electrically conductive members with respective rear surfaces and grit blasted front surfaces with a nerve cuff body, which includes a respective plurality of windows, in such a manner that exposed portions of the grit blasted front surfaces are within the windows.
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Shelton, Brian Michael
Mech, Brian
Klein, Valma
Talbot, Neil
Greenberg, Robert
Abrégé
The present disclosure generally relates to systems and methods for a stimulation system. Various aspects of the present disclosure relate generally to the treatment of epilepsy, depression and/or other conditions in a subject using a nerve stimulator and, more particularly, to an effective and quicker titration method for selection of stimulation parameters of the nerve stimulator using biological markers that indicate potential therapeutic effects. Some aspects of the present disclosure may utilize a pupillometry sensor synchronized with the VNS stimulation system to compare pupil size of a subject with stimulation on and off and for obtaining filtered pupil response measurements after stimulating each electrode while modulating the stimulation parameters. Thus, aspects of the present disclosure allow for quicker titration of programmable stimulation parameters (e.g., stimulation pulse amplitude) to levels that cause a therapeutic result in a matter of minutes instead of months as compared to related VNS systems.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
11.
STIMULATOR SYSTEMS AND METHODS FOR SELECTIVELY RECRUITING FASCICLES IN HYPOGLOSSAL NERVE TRUNK
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Ng, Boon Khai
Calderon, Joseph L.
Abrégé
An electrode lead comprises a lead body, connector contacts affixed to the proximal end of the lead body, and a cuff body affixed to the distal end of the lead body. The cuff body is pre-shaped to transition from an unfurled state to a furled state, wherein the cuff body, when in the furled state has an inner surface for contacting a nerve and an overlapping inner cuff region and an outer cuff region. The electrode lead further comprise electrode contacts circumferentially disposed along the cuff body when in the furled state, such that at least one of the electrode contacts is located on the inner surface of the cuff body, and at least another of the electrode contacts is located between the overlapping inner and outer cuff regions. The electrode lead further comprises electrical conductors extending through the lead body respectively between the connector contacts and the electrode contacts.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
12.
DEVICES AND METHODS FOR STIMULATING AN AURICULAR BRANCH OF A VAGUS NERVE
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian Michael
Talbot, Neil
Dearden, Brian
Abrégé
A stimulation device includes a first transmitting coil and a drive circuit electrically coupled to the first transmitting coil and configured to drive the first transmitting coil. The first transmitting coil is configured, when the device is in proximity to a person's ear and the first transmitting coil is driven with a time-varying electric current providable by the drive circuit, to generate at least part of a magnetic field providing a time-varying magnetic flux across an auricular branch of a Vagus Nerve (ABVN) sufficient to activate the ABVN.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian Michael
Mech, Brian
Klein, Valma
Talbot, Neil
Greenberg, Robert J.
Abrégé
The present disclosure generally relates to systems and methods for a stimulation system. Various aspects of the present disclosure relate generally to the treatment of epilepsy, depression and/or other conditions in a subject using a nerve stimulator and, more particularly, to an effective and quicker titration method for selection of stimulation parameters of the nerve stimulator using biological markers that indicate potential therapeutic effects. Some aspects of the present disclosure may utilize a pupillometry sensor synchronized with the VNS stimulation system to compare pupil size of a subject with stimulation on and off and for obtaining filtered pupil response measurements after stimulating each electrode while modulating the stimulation parameters. Thus, aspects of the present disclosure allow for quicker titration of programmable stimulation parameters (e.g., stimulation pulse amplitude) to levels that cause a therapeutic result in a matter of minutes instead of months as compared to related VNS systems.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 3/00 - Appareils pour l'examen optique des yeux; Appareils pour l'examen clinique des yeux
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
14.
DEVICES AND METHODS FOR STIMULATING AN AURICULAR BRANCH OF A VAGUS NERVE
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Shelton, Brian Michael
Talbot, Neil
Dearden, Brian
Abrégé
A stimulation device includes a first transmitting coil and a drive circuit electrically coupled to the first transmitting coil and configured to drive the first transmitting coil. The first transmitting coil is configured, when the device is in proximity to a person's ear and the first transmitting coil is driven with a time-varying electric current providable by the drive circuit, to generate at least part of a magnetic field providing a time-varying magnetic flux across an auricular branch of a Vagus Nerve (ABVN) sufficient to activate the ABVN.
H01F 7/06 - Electro-aimants; Actionneurs comportant des électro-aimants
A61N 2/02 - Magnétothérapie utilisant des champs magnétiques produits par des bobines, y compris par des boucles à spire unique ou par des électro-aimants
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Shelton, Brian Michael
Mech, Brian
Klein, Valma
Talbot, Neil
Hotlani, Hitesh
Abrégé
The disclosure provides systems and methods for automatically titrating an electrical pulse amplitude for a patient-implanted VNS stimulator. One or more external sensors (e.g., EEG, EKG, EMG, auditory sensors, inertial motion sensors, etc.) can be applied to the patient to generate data relevant to an acceptable amplitude of the electrical pulse for a given cathode in a multi-cathode cuff. In one embodiment, the device may include a controller on the implanted VNS stimulator that receives data, e.g., using a wireless connection, from the external sensors and titrates upward the amplitude until an acceptable amplitude is determine that provides efficacy with minimal, if any, side effects.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
16.
AUTOMATICALLY-ALIGNING MAGNETIC FIELD SYSTEM AND METHOD OF FABRICATION
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Lin, Susanna
Dearden, Brian R.
Loo, Justin Cheng-Tsu
Abrégé
A wireless power transfer device includes a first transmitting coil oriented along a first axis and including a first ferrite rod; a second transmitting coil on the first transmitting coil, oriented along a second axis different from the first axis, and including a second ferrite rod; and a nonmagnetic layer magnetically decoupling the first ferrite rod from the second ferrite rod in an area of overlap between the first and second ferrite rods, the first ferrite rod and the nonmagnetic layer being fabricated utilizing additive manufacturing.
B22F 12/41 - Moyens de rayonnement caractérisés par le type, p.ex. laser ou faisceau d’électrons
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
B22F 10/25 - Dépôt direct de particules métalliques, p.ex. dépôt direct de métal [DMD] ou mise en forme par laser [LENS]
H02J 50/10 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Shelton, Brian Michael
Hotlani, Hitesh
Abrégé
The disclosure provides systems and methods for system for vagus nerve stimulation (VNS), using a VNS stimulator implanted in a human subject and configured to transmit electrical stimulation pulses to a vagus nerve of the human subject; and at least one sensor configured to detect a predefined pattern of tactile input, a bodily gesture, and/or a voice command from the human subject, wherein the VNS stimulator includes a controller configured to modulate at least one stimulation parameter of the electrical stimulation pulses based at least in part on the tactile input, bodily gesture, and/or voice command from the human subject.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/02 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet - Parties constitutives
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian Michael
Mech, Brian
Klein, Valma
Talbot, Neil
Hotlani, Hitesh
Abrégé
The disclosure provides systems and methods for automatically titrating an electrical pulse amplitude for a patient-implanted VNS stimulator. One or more external sensors (e.g., EEG, EKG, EMG, auditory sensors, inertial motion sensors, etc.) can be applied to the patient to generate data relevant to an acceptable amplitude of the electrical pulse for a given cathode in a multi-cathode cuff. In one embodiment, the device may include a controller on the implanted VNS stimulator that receives data, e.g., using a wireless connection, from the external sensors and titrates upward the amplitude until an acceptable amplitude is determine that provides efficacy with minimal, if any, side effects.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian Michael
Hotlani, Hitesh
Abrégé
The disclosure provides systems and methods for system for vagus nerve stimulation (VNS), using a VNS stimulator implanted in a human subject and configured to transmit electrical stimulation pulses to a vagus nerve of the human subject; and at least one sensor configured to detect a predefined pattern of tactile input, a bodily gesture, and/or a voice command from the human subject, wherein the VNS stimulator includes a controller configured to modulate at least one stimulation parameter of the electrical stimulation pulses based at least in part on the tactile input, bodily gesture, and/or voice command from the human subject.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
20.
AUTOMATICALLY-ALIGNING MAGNETIC FIELD SYSTEM AND METHOD OF FABRICATION
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Lin, Susanna
Dearden, Brian
Loo, Justin
Abrégé
A wireless power transfer device (10) includes a first transmitting coil (100) oriented along a first axis (100a) and including a first ferrite rod (120); a second transmitting coil (200) on the first transmitting coil (100), oriented along a second axis (200a) different from the first axis (100a), and including a second ferrite rod (220); and a nonmagnetic layer (300L) magnetically decoupling the first ferrite rod (120) from the second ferrite rod (220) in an area of overlap (300) between the first and second ferrite rods (120, 220), the first ferrite rod (120) and the nonmagnetic layer (300L) being fabricated utilizing additive manufacturing.
H01F 41/02 - Appareils ou procédés spécialement adaptés à la fabrication ou à l'assemblage des aimants, des inductances ou des transformateurs; Appareils ou procédés spécialement adaptés à la fabrication des matériaux caractérisés par leurs propriétés magnétiques pour la fabrication de noyaux, bobines ou aimants
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Calderon, Joseph, L.
Hillery, Edward
Lin, Susanna, M.
Abrégé
An implantable medical device (IMD) charger apparatus may include an IMD charger including a housing defining a bottom surface, a primary coil located within the housing, and a fastener on the bottom surface of the housing, and a charger support, mounted on the IMD charger, including a bottom surface, and movable between a first state and a second state. The IMD charger and the charger support may be respectively configured such that the IMD charger fastener is above the charger support bottom surface when the charger support is in the first state and the IMD charger fastener is at or below the charger support bottom surface when the charger support is in the second state.
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
H01F 27/00 - AIMANTS; INDUCTANCES; TRANSFORMATEURS; EMPLOI DE MATÉRIAUX SPÉCIFIÉS POUR LEURS PROPRIÉTÉS MAGNÉTIQUES - Détails de transformateurs ou d'inductances, en général
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Calderon, Joseph L.
Hillery, Edward
Lin, Susanna M.
Abrégé
An implantable medical device (IMD) charger apparatus may include an IMD charger including a housing defining a bottom surface, a primary coil located within the housing, and a fastener on the bottom surface of the housing, and a charger support, mounted on the IMD charger, including a bottom surface, and movable between a first state and a second state. The IMD charger and the charger support may be respectively configured such that the IMD charger fastener is above the charger support bottom surface when the charger support is in the first state and the IMD charger fastener is at or below the charger support bottom surface when the charger support is in the second state.
H02J 50/10 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif
H02J 7/00 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries
H02J 50/90 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la détection ou l'optimisation de la position, p.ex. de l'alignement
The Alfred E Mann Foundation for Scientific Research (USA)
Inventeur(s)
Farkas, Leslie G.
Dearden, Brian R.
Loo, Justin Cheng-Tsu
Abrégé
A wireless power transfer system includes a wireless power transfer device. The wireless power transfer device includes a first transmitting coil oriented along a first axis; a second transmitting coil on the first transmitting coil and oriented along a second axis different from the first axis; and a nonmagnetic material magnetically decoupling the first transmitting coil from the second transmitting coil in an area of overlap between the first and second transmitting coils.
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
H02J 50/70 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la réduction des champs de fuite électriques, magnétiques ou électromagnétiques
H02J 50/80 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre l’échange de données, concernant l’alimentation ou la distribution d’énergie électrique, entre les dispositifs de transmission et les dispositifs de réception
H02J 50/90 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la détection ou l'optimisation de la position, p.ex. de l'alignement
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Farkas, Leslie
Dearden, Brian
Loo, Justin
Abrégé
A wireless power transfer system includes a wireless power transfer device. The wireless power transfer device includes a first transmitting coil oriented along a first axis; a second transmitting coil on the first transmitting coil and oriented along a second axis different from the first axis; and a nonmagnetic material magnetically decoupling the first transmitting coil from the second transmitting coil in an area of overlap between the first and second transmitting coils.
H02J 50/00 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
H02J 50/80 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre l’échange de données, concernant l’alimentation ou la distribution d’énergie électrique, entre les dispositifs de transmission et les dispositifs de réception
25.
SYSTEMS AND METHODS FOR VAGUS NERVE MONITORING AND STIMULATION
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Mech, Brian V.
Talbot, Neil
Shelton, Brian M.
Calderon, Joseph L.
Greenberg, Robert J.
Abrégé
The present disclosure generally relates to devices, systems, and methods for detecting, monitoring, predicting, and/or treating medical conditions (e.g, epileptic seizures) using one or more sensors configured to collect biomarker data from a human subject (e.g, vagal tone and/or physiological or other biomarkers).
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Mech, Brian V.
Talbot, Neil
Shelton, Brian M.
Calderon, Joseph L.
Greenberg, Robert J.
Abrégé
The present disclosure generally relates to devices, systems, and methods for detecting, monitoring, predicting, and/or treating medical conditions (e.g., epileptic seizures) using one or more sensors configured to collect biomarker data from a human subject (e.g., vagal tone and/or physiological or other biomarkers).
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Jenney, Christopher, Reed
Strickland, Timothy
Abrégé
An electrode lead including an elongate lead body and a nerve cuff (or other nerve contact element) including an electrically insulative cuff body (or other contact body) affixed to the distal end of the lead body and at least one electrically conductive coil partially embedded in the cuff body (or other contact body) such that there are non-embedded portions, which together define a flexible coil contact that is associated with the front outer surface of the cuff body (or other contact body), and embedded portions.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Schmidt, Siegmar
Dai, William A.
Ng, Boon Khai
Abrégé
Pressure sensors having ring-tensioned membranes are disclosed. A tensioning ring is bonded to a membrane in a manner that results in the tensioning ring applying a tensile force to the membrane, flattening the membrane and reducing or eliminating defects that may have occurred during production. The membrane is bonded to the sensor housing at a point outside the tensioning ring, preventing the process of bonding the membrane to the housing from introducing defects into the tensioned portion of the membrane. A dielectric may be introduced into the gap between the membrane and the counter electrode in a capacitive pressure sensor, resulting in an improved dynamic range.
G01L 9/00 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pression; Transmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent
G01L 19/06 - Moyens pour empêcher la surcharge ou l'influence délétère du milieu à mesurer sur le dispositif de mesure ou vice versa
G01L 19/04 - Moyens pour compenser les effets des variations de température
G01L 1/14 - Mesure des forces ou des contraintes, en général en mesurant les variations de la capacité ou de l'inductance des éléments électriques, p.ex. en mesurant les variations de fréquence des oscillateurs électriques
G01L 9/12 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pression; Transmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent en faisant usage des variations de la capacité
G01L 7/08 - Mesure de la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments mécaniques ou hydrauliques sensibles à la pression sous forme de jauges, élastiquement déformables du type à diaphragme élastique
29.
STIMULATOR SYSTEMS AND METHODS FOR OBSTRUCTIVE SLEEP APNEA
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Suri, Harshit
Calderon, Joseph L.
Molnar, Gregory Frederick
Goding, Jr., George S.
Atyabi, Alanie
Schmidt, Siegmar
Dai, William
Dearden, Brian
Keenan, Desmond B.
Abrégé
An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p.ex. laryngoscopes, bronchoscopes
A61B 5/083 - Mesure du taux de métabolisme en utilisant un essai respiratoire, p.ex. mesure du taux de consommation d'oxygène
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
A61B 5/394 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG] spécialement adaptée pour l’électroglottographie ou l’électropalatographie
30.
ELECTRODE LEADS HAVING NERVE CONTACT ELEMENTS WITH COIL CONTACTS AND ASSOCIATED SYSTEMS AND METHODS
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Jenney, Christopher Reed
Strickland, Timothy
Abrégé
An electrode lead including an elongate lead body and a nerve cuff (or other nerve contact element) including an electrically insulative cuff body (or other contact body) affixed to the distal end of the lead body and at least one electrically conductive coil partially embedded in the cuff body (or other contact body) such that there are non-embedded portions, which together define a flexible coil contact that is associated with the front outer surface of the cuff body (or other contact body), and embedded portions.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
31.
METHOD AND APPARATUS FOR PRE-ALIGNMENT OF AN AUTOMATICALLY ALIGNING MAGNETIC FIELD SYSTEM
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian
Shelton, Brian
Farkas, Leslie G.
Abrégé
A wireless power transfer system includes a wireless power transfer device configured to determine a magnetic field, from among a plurality of directionally different potential magnetic fields that the wireless power transfer device is configured to generate, that has, at a receiver coil of an electronic device, a direction aligned with the receiver coil.
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
H02J 50/12 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif du type couplage à résonance
H02J 50/80 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre l’échange de données, concernant l’alimentation ou la distribution d’énergie électrique, entre les dispositifs de transmission et les dispositifs de réception
G01R 19/00 - Dispositions pour procéder aux mesures de courant ou de tension ou pour en indiquer l'existence ou le signe
G01P 15/02 - Mesure de l'accélération; Mesure de la décélération; Mesure des chocs, c. à d. d'une variation brusque de l'accélération en ayant recours aux forces d'inertie
32.
METHOD AND APPARATUS FOR PRE-ALIGNMENT OF AN AUTOMATICALLY ALIGNING MAGNETIC FIELD SYSTEM
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian
Shelton, Brian
Farkas, Leslie G.
Abrégé
A wireless power transfer system includes a wireless power transfer device configured to determine a magnetic field, from among a plurality of directionally different potential magnetic fields that the wireless power transfer device is configured to generate, that has, at a receiver coil of an electronic device, a direction aligned with the receiver coil.
H02J 7/02 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries pour la charge des batteries par réseaux à courant alternatif au moyen de convertisseurs
H02J 50/00 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
H02J 50/70 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la réduction des champs de fuite électriques, magnétiques ou électromagnétiques
33.
WAKEFULNESS AND SLEEP STAGE DETECTION USING RESPIRATION EFFORT VARIABILITY
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian Michael
Elyahoodayan, Sahar
Abrégé
The present disclosure generally relates to systems and methods for monitoring and/or the sleep stage of an individual using one or more sensors, and methods of treating medical conditions related thereto (e.g., obstructive sleep apnea).
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
A61B 5/113 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre se produisant au cours de la respiration
34.
ELECTRODE LEADS HAVING MULTI-APPLICATION HELICAL NERVE CUFFS AND ASSOCIATED SYSTEMS AND METHODS
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Brandt, William Andrew
Dearden, Brian Ralph
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative helical cuff body configured to be disposed around a nerve, and a plurality of electrically conductive contacts carried by the helical cuff body that are spaced from one another.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
35.
Electrode leads having multi-application helical nerve cuffs and associated systems and methods
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Brandt, William Andrew
Dearden, Brian Ralph
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative helical cuff body configured to be disposed around a nerve, and a plurality of electrically conductive contacts carried by the helical cuff body that are spaced from one another.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
36.
ELECTRODE LEADS HAVING MULTI-APPLICATION HELICAL NERVE CUFFS AND ASSOCIATED SYSTEMS AND METHODS
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Brandt, William, Andrew
Dearden, Brian, Ralph
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative helical cuff body configured to be disposed around a nerve, and a plurality of electrically conductive contacts carried by the helical cuff body that are spaced from one another.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Conducting medical and scientific research, and developing technology in the field of medical devices to bring advanced, innovative medical technologies to the public to improve the health and quality of life for people suffering from debilitating medical conditions; Compiling and analyzing data for research purposes in the field of medical devices; Medical, clinical, engineering and scientific research and development in the fields of medical devices, sensors and components thereof, and healthcare IT and infrastructure; Medical and scientific research, namely, conducting preclinical and clinical trials for others
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Conducting medical and scientific research, and developing technology in the field of medical devices, to bring advanced, innovative medical technologies to the public to improve the health and quality of life for people suffering from debilitating medical conditions; Compiling and analyzing data for research purposes in the field of medical devices; Medical, clinical, engineering and scientific research and development in the fields of medical devices, sensors and components thereof, and healthcare IT and infrastructure; Medical and scientific research, namely, conducting preclinical and clinical trials for others, all of the foregoing excluding consultation and research in the field of aerospace engineering and technology consultation and research in the field of aerospace engineering
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Mech, Brian
Greenberg, Robert
Abrégé
The disclosure provides systems and methods for neuromodulation using a housing that at least partially contains a stimulator assembly, wherein the stimulator assembly is configured to generate vibration by mechanical oscillation and/or using a sound wave; and wherein the vibration generated by the stimulator assembly is configured to therapeutically treat the subject by stimulating one or more nerves when the housing is placed in proximity to or on a skin surface of a subject.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Mech, Brian V.
Greenberg, Robert J.
Abrégé
The disclosure provides systems and methods for neuromodulation using a housing that at least partially contains a stimulator assembly, wherein the stimulator assembly is configured to generate vibration by mechanical oscillation and/or using a sound wave; and wherein the vibration generated by the stimulator assembly is configured to therapeutically treat the subject by stimulating one or more nerves when the housing is placed in proximity to or on a skin surface of a subject.
A61N 1/00 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet
A61N 1/02 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet - Parties constitutives
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/08 - Aménagements ou circuits de surveillance, de protection, de commande ou d'indication
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Mech, Brian V.
Greenberg, Robert J.
Abrégé
The disclosure provides systems and methods for neuromodulation using a housing that at least partially contains a stimulator assembly, wherein the stimulator assembly is configured to generate vibration by mechanical oscillation and/or using a sound wave; and wherein the vibration generated by the stimulator assembly is configured to therapeutically treat the subject by stimulating one or more nerves when the housing is placed in proximity to or on a skin surface of a subject.
A61N 1/00 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet
A61N 1/02 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet - Parties constitutives
A61N 1/08 - Aménagements ou circuits de surveillance, de protection, de commande ou d'indication
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
42.
NERVE CUFF ELECTRODES FABRICATED USING OVER-MOLDED LCP SUBSTRATES
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Schmidt, Siegmar
Ng, Boon Khai
Abrégé
An electrode lead may comprise a flexible circuit that includes a planar dielectric substrate including an elongated lead substrate portion having opposing ends, an electrode carrying substrate portion disposed on one end of the lead substrate portion, and a connector substrate portion disposed on the other end of the lead substrate portion, wherein the lead substrate portion is pre-shaped into a three-dimensional structure. The flexible circuit may further include an electrically conductive trace extending from the connector substrate portion to the electrode carrying substrate portion, a first window formed in the connector substrate portion to expose the electrically conductive trace to form a connector pad, and a second window formed in the electrode carrying substrate portion to expose the electrically conductive trace to form an electrode pad. The electrode lead may further comprise a lead connector that incorporates the connector substrate portion.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Jenney, Christopher Reed
Gotlib, Oren
Calderon, Joseph
Brandt, William Andrew
Talbot, Neil
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Jenney, Christopher Reed
Gotlib, Oren
Calderon, Joseph
Brandt, William Andrew
Talbot, Neil
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Jenney, Christopher, Reed
Gotlib, Oren
Calderon, Joseph
Brandt, William, Andrew
Talbot, Neil
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E, MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Schmidt, Siegmar
Ng, Boon Khai
Abrégé
An electrode lead may comprise a flexible circuit that includes a planar dielectric substrate including an elongated lead substrate portion having opposing ends, an electrode carrying substrate portion disposed on one end of the lead substrate portion, and a connector substrate portion disposed on the other end of the lead substrate portion, wherein the lead substrate portion is pre-shaped into a three-dimensional structure. The flexible circuit may further include an electrically conductive trace extending from the connector substrate portion to the electrode carrying substrate portion, a first window formed in the connector substrate portion to expose the electrically conductive trace to form a connector pad, and a second window formed in the electrode carrying substrate portion to expose the electrically conductive trace to form an electrode pad. The electrode lead may further comprise a lead connector that incorporates the connector substrate portion.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Mech, Brian V.
Greenberg, Robert J.
Abrégé
The disclosure provides systems and methods for detecting, monitoring, and/or treating obstructive sleep apnea, as well as other conditions, using vital sign and/or biometric data collected and/or imputed from one or more photoplethysmography sensors in conjunction with vital sign and/or biometric data from one or more additional sensors such as activity, body position, ECG, HR, or SpO2 levels, e.g., as feedback to control therapy and/or to titrate therapy on a periodic basis.
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
48.
PHOTOPLETHYSMOGRAPHY IN COMBINATION WITH MEDICAL DEVICES
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Mech, Brian
Greenberg, Robert
Abrégé
The disclosure provides systems and methods for detecting, monitoring, and/or treating obstructive sleep apnea, as well as other conditions, using vital sign and/or biometric data collected and/or imputed from one or more photoplethysmography sensors in conjunction with vital sign and/or biometric data from one or more additional sensors such as activity, body position, ECG, HR, or SpO2 levels, e.g., as feedback to control therapy and/or to titrate therapy on a periodic basis.
A61N 1/365 - Stimulateurs cardiaques commandés par un paramètre physiologique, p.ex. par le potentiel cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
A61B 5/02 - Mesure du pouls, du rythme cardiaque, de la pression sanguine ou du débit sanguin; Détermination combinée du pouls, du rythme cardiaque, de la pression sanguine; Evaluation d'un état cardio-vasculaire non prévue ailleurs, p.ex. utilisant la combinaison de techniques prévues dans le présent groupe et des techniques d'électrocardiographie; Sondes cardiaques pour mesurer la pression sanguine
50.
System and method for authenticating wireless programming devices in programmable medical systems
THE ALFRED E. MANN FOUNDATION FOR SCIENTIC RESEARCH (USA)
Inventeur(s)
Rodriguez, Saul
Han, Dianna (dan)
Istoc, Emil
Abrégé
A medical device of a medical system is configured for communicating with an external programmer over a wireless communications link. The medical device comprises a wireless communications module configured for receiving a first unencrypted version of a random number and a first encrypted version of the random number from the external programmer over the wireless communications link. The medical device further comprises control circuitry configured for performing an authentication procedure on the external programmer based on the first unencrypted version of the random number and the first encrypted version of the random number, and preventing the external programmer from commanding the medical device to perform an action unless the authentication procedure is successful.
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p.ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
H04L 69/40 - Dispositions, protocoles ou services de réseau indépendants de la charge utile de l'application et non couverts dans un des autres groupes de la présente sous-classe pour se remettre d'une défaillance d'une instance de protocole ou d'une entité, p.ex. protocoles de redondance de service, état de redondance de protocole ou redirection de service de protocole
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
H04L 67/141 - Configuration des sessions d'application
H04L 67/53 - Services réseau en utilisant des fournisseurs tiers de services
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
H04Q 9/00 - Dispositions dans les systèmes de commande à distance ou de télémétrie pour appeler sélectivement une sous-station à partir d'une station principale, sous-station dans laquelle un appareil recherché est choisi pour appliquer un signal de commande ou
H04W 12/04 - Gestion des clés, p.ex. par architecture d’amorçage générique [GBA]
G06F 21/62 - Protection de l’accès à des données via une plate-forme, p.ex. par clés ou règles de contrôle de l’accès
51.
System and method for authenticating wireless programming system and method for authenticating wireless programming devices in programmable medical systems
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Rodriguez, Saul
Han, Dianna (dan)
Istoc, Emil
Abrégé
A medical device of a medical system is configured for communicating with an external programmer over a wireless communications link. The medical device comprises a wireless communications module configured for receiving a first unencrypted version of a random number and a first encrypted version of the random number from the external programmer over the wireless communications link. The medical device further comprises control circuitry configured for performing an authentication procedure on the external programmer based on the first unencrypted version of the random number and the first encrypted version of the random number, and preventing the external programmer from commanding the medical device to perform an action unless the authentication procedure is successful.
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p.ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
H04L 69/40 - Dispositions, protocoles ou services de réseau indépendants de la charge utile de l'application et non couverts dans un des autres groupes de la présente sous-classe pour se remettre d'une défaillance d'une instance de protocole ou d'une entité, p.ex. protocoles de redondance de service, état de redondance de protocole ou redirection de service de protocole
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
H04L 67/141 - Configuration des sessions d'application
H04L 67/53 - Services réseau en utilisant des fournisseurs tiers de services
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
H04Q 9/00 - Dispositions dans les systèmes de commande à distance ou de télémétrie pour appeler sélectivement une sous-station à partir d'une station principale, sous-station dans laquelle un appareil recherché est choisi pour appliquer un signal de commande ou
H04W 12/04 - Gestion des clés, p.ex. par architecture d’amorçage générique [GBA]
G06F 21/62 - Protection de l’accès à des données via une plate-forme, p.ex. par clés ou règles de contrôle de l’accès
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Kohler, Daniel G.
Abrégé
A method of multi-factor authentication includes receiving, by a first electronic device, a partial digital certificate including partial certificate information omitting at least one authentication factor from complete certificate information, and a signature encrypting a first hash of the complete certificate information with a certificate authority private key. The method also includes obtaining the first hash by decrypting, by the first electronic device, the signature with a certificate authority public key corresponding to the certificate authority private key; generating, by the first electronic device, a second hash based on the partial certificate information in the partial digital certificate and the at least one authentication factor; and comparing, by the first electronic device, the second hash to the first hash.
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Kohler, Daniel G.
Abrégé
A method of multi-factor authentication includes receiving, by a first electronic device, a partial digital certificate including partial certificate information omitting at least one authentication factor from complete certificate information, and a signature encrypting a first hash of the complete certificate information with a certificate authority private key. The method also includes obtaining the first hash by decrypting, by the first electronic device, the signature with a certificate authority public key corresponding to the certificate authority private key; generating, by the first electronic device, a second hash based on the partial certificate information in the partial digital certificate and the at least one authentication factor; and comparing, by the first electronic device, the second hash to the first hash.
G06F 21/33 - Authentification de l’utilisateur par certificats
G06F 21/34 - Authentification de l’utilisateur impliquant l’utilisation de dispositifs externes supplémentaires, p.ex. clés électroniques ou cartes à puce intelligentes
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Klein, Valma
Abrégé
A multi-electrode ear shell includes an inner surface and an outer surface, the inner surface corresponding to a surface of an ear and being configured to overlap a cymba and a cavum of the ear. The multi-electrode ear shell further includes a first socket to receive a first stimulation electrode and a second socket to receive a second stimulation electrode.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Klein, Valma
Abrégé
A multi-electrode ear shell includes an inner surface and an outer surface, the inner surface corresponding to a surface of an ear and being configured to overlap a cymba and a cavum of the ear. The multi-electrode ear shell further includes a first socket to receive a first stimulation electrode and a second socket to receive a second stimulation electrode.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Elyahoodayan, Sahar
Shelton, Brian M.
Talbot, Neil H.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, wherein the IMU is configured to detect chest and/or abdominal movement by a patient during the inspiration and expiration stages of a respiratory cycle and to generate positional data based on the detected movement. Positional data generated by the IMU is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61F 5/56 - Dispositifs pour prévenir le ronflement
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
57.
STIMULATION SYSTEM INCLUDING A MULTI-ELECTRODE EAR SHELL AND METHOD OF USING THE SAME
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Klein, Valma
Abrégé
A multi-electrode ear shell includes an inner surface and an outer surface, the inner surface corresponding to a surface of an ear and being configured to overlap a cymba and a cavum of the ear. The multi-electrode ear shell further includes a first socket to receive a first stimulation electrode and a second socket to receive a second stimulation electrode.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian R.
Loo, Justin Cheng-Tsu
Abrégé
A wireless power transfer system includes a wireless power transfer device. The wireless power transfer device includes a first transmitting coil oriented along a first axis; a second transmitting coil on the first transmitting coil and oriented along a second axis different from the first axis; and a nonmagnetic material magnetically decoupling the first transmitting coil from the second transmitting coil in an area of overlap between the first and second transmitting coils.
H02J 50/00 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique
H02J 50/70 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la réduction des champs de fuite électriques, magnétiques ou électromagnétiques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian R.
Loo, Justin Cheng-Tsu
Abrégé
A wireless power transfer system includes a wireless power transfer device. The wireless power transfer device includes a first transmitting coil oriented along a first axis; a second transmitting coil on the first transmitting coil and oriented along a second axis different from the first axis; and a nonmagnetic material magnetically decoupling the first transmitting coil from the second transmitting coil in an area of overlap between the first and second transmitting coils.
H02J 50/00 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique
H02J 50/70 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la réduction des champs de fuite électriques, magnétiques ou électromagnétiques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Elyahoodayan, Sahar
Shelton, Brian M.
Talbot, Neil H.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, wherein the IMU is configured to detect chest and/or abdominal movement by a patient during the inspiration and expiration stages of a respiratory cycle and to generate positional data based on the detected movement. Positional data generated by the IMU is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61F 5/56 - Dispositifs pour prévenir le ronflement
A61N 1/00 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Elyahoodayan, Sahar
Shelton, Brian M.
Talbot, Neal H.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, wherein the IMU is configured to detect chest and/or abdominal movement by a patient during the inspiration and expiration stages of a respiratory cycle and to generate positional data based on the detected movement. Positional data generated by the IMU is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61F 5/56 - Dispositifs pour prévenir le ronflement
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Elyahoodayan, Sahar
Shelton, Brian, M.
Talbot, Neal, H.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, wherein the IMU is configured to detect chest and/or abdominal movement by a patient during the inspiration and expiration stages of a respiratory cycle and to generate positional data based on the detected movement. Positional data generated by the IMU is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/00 - SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE ÉLECTROTHÉRAPIE; MAGNÉTOTHÉRAPIE; THÉRAPIE PAR RADIATIONS; THÉRAPIE PAR ULTRASONS Électrothérapie; Circuits à cet effet
A61F 5/56 - Dispositifs pour prévenir le ronflement
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Elyahoodayan, Sahar
Shelton, Brian M.
Talbot, Neal H.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, wherein the IMU is configured to detect chest and/or abdominal movement by a patient during the inspiration and expiration stages of a respiratory cycle and to generate positional data based on the detected movement. Positional data generated by the IMU is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Dearden, Brian R.
Loo, Justin Cheng-Tsu
Abrégé
A wireless power transfer system includes a wireless power transfer device. The wireless power transfer device includes a first transmitting coil oriented along a first axis; a second transmitting coil on the first transmitting coil and oriented along a second axis different from the first axis; and a nonmagnetic material magnetically decoupling the first transmitting coil from the second transmitting coil in an area of overlap between the first and second transmitting coils.
H02J 50/90 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre la détection ou l'optimisation de la position, p.ex. de l'alignement
H02J 50/10 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif
H02J 50/40 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant plusieurs dispositifs de transmission ou de réception
H02J 50/00 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique
H02J 50/80 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre l’échange de données, concernant l’alimentation ou la distribution d’énergie électrique, entre les dispositifs de transmission et les dispositifs de réception
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Elyahoodayan, Sahar
Shelton, Brian M.
Talbot, Neal H.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, wherein the IMU is configured to detect chest and/or abdominal movement by a patient during the inspiration and expiration stages of a respiratory cycle and to generate positional data based on the detected movement. Positional data generated by the IMU is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
66.
ELECTRODE LEADS HAVING MULTI-APPLICATION NERVE CUFFS AND ASSOCIATED SYSTEMS AND METHODS
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian Ralph
Shelton, Brian M.
Talbot, Neil
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
67.
ELECTRODE LEADS HAVING MULTI-APPLICATION NERVE CUFFS AND ASSOCIATED SYSTEMS AND METHODS
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian Ralph
Shelton, Brian, M.
Talbot, Neil
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
68.
ELECTRODE LEADS HAVING MULTI-APPLICATION NERVE CUFFS AND ASSOCIATED SYSTEMS AND METHODS
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Dearden, Brian Ralph
Shelton, Brian M.
Talbot, Neil
Abrégé
An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian M.
Elyahoodayan, Sahar
Suri, Harshit R.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an acoustic sensor configured to detect acoustic sounds generated by the heart and lungs. Sensory data from the acoustic sensor is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/113 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre se produisant au cours de la respiration
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian M.
Elyahoodayan, Sahar
Suri, Harshit R.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an acoustic sensor configured to detect acoustic sounds generated by the heart and lungs. Sensory data from the acoustic sensor is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/113 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre se produisant au cours de la respiration
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Shelton, Brian M.
Elyahoodayan, Sahar
Suri, Harshit R.
Abrégé
The disclosure provides systems and methods for treating obstructive sleep apnea using an acoustic sensor configured to detect acoustic sounds generated by the heart and lungs. Sensory data from the acoustic sensor is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Greenberg, Robert J.
Suri, Harshit R.
Calderon, Joseph L.
Dearden, Brian R.
Abrégé
Systems for treating obstructive sleep apnea having an implanted stimulator with an internal sensor configured to generate sensory data corresponding to movement of the thoracic or abdominal cavity of a patient during respiration. The system includes a wireless communications link between the stimulator and at least one external sensor for sensing a patient's physiological parameter and is used to augment the sensory data from the internal sensor. The stimulator includes a stimulation system configured to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve to treat sleep apnea.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Greenberg, Robert J.
Suri, Harshit R.
Calderon, Joseph L.
Dearden, Brian R.
Abrégé
Systems for treating obstructive sleep apnea having an implanted stimulator with an internal sensor configured to generate sensory data corresponding to movement of the thoracic or abdominal cavity of a patient during respiration. The system includes a wireless communications link between the stimulator and at least one external sensor for sensing a patient's physiological parameter and is used to augment the sensory data from the internal sensor. The stimulator includes a stimulation system configured to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve to treat sleep apnea.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Greenberg, Robert J.
Suri, Harshit R.
Calderon, Joseph L.
Dearden, Brian R.
Abrégé
Systems for treating obstructive sleep apnea having an implanted stimulator with an internal sensor configured to generate sensory data corresponding to movement of the thoracic or abdominal cavity of a patient during respiration. The system includes a wireless communications link between the stimulator and at least one external sensor for sensing a patient's physiological parameter and is used to augment the sensory data from the internal sensor. The stimulator includes a stimulation system configured to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve to treat sleep apnea.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Ng, Boon Khai
Schmidt, Siegmar
Abrégé
A lead comprising a lead body, a lead connector terminal affixed to a proximal end of the lead body, and a cuff body affixed to a distal end of the lead body, an electrode contact affixed to the cuff body, and an electrical conductor between the connector terminal and electrode contact. The lead further comprises a strap extending from a first region of the cuff body, a buckle disposed on a second region of the cuff body, and a locking feature, e.g., protuberance, ring, or wrinkle, associated with the strap. The locking feature is configured for being pulled through the buckle to dispose the cuff body around a nerve in response to a tensile force applied to the strap. The locking feature is configured for abutting an edge of the buckle in response to a release of the tensile force to secure the cuff body around the nerve.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIC RESEARCH (USA)
Inventeur(s)
Ng, Boon Khai
Calderon, Joseph L.
Abrégé
An electrode lead comprises a lead body, connector contacts affixed to the proximal end of the lead body, and a cuff body affixed to the distal end of the lead body. The cuff body is pre-shaped to transition from an unfurled state to a furled state, wherein the cuff body, when in the furled state has an inner surface for contacting a nerve and an overlapping inner cuff region and an outer cuff region. The electrode lead further comprise electrode contacts circumferentially disposed along the cuff body when in the furled state, such that at least one of the electrode contacts is located on the inner surface of the cuff body, and at least another of the electrode contacts is located between the overlapping inner and outer cuff regions. The electrode lead further comprises electrical conductors extending through the lead body respectively between the connector contacts and the electrode contacts.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
A61B 5/394 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG] spécialement adaptée pour l’électroglottographie ou l’électropalatographie
77.
IMPLANTABLE INFUSION DEVICES WITH CLOSED LOOP SENSING AND ASSOCIATED METHODS
A61M 5/142 - Perfusion sous pression, p.ex. utilisant des pompes
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61M 5/172 - Moyens pour commander l'écoulement des agents vers le corps ou pour doser les agents à introduire dans le corps, p.ex. compteurs de goutte-à-goutte électriques ou électroniques
A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
78.
IMPLANTABLE INFUSION DEVICES WITH CLOSED LOOP SENSING AND ASSOCIATED METHODS
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Suri, Harshit
Calderon, Joseph L.
Molnar, Gregory Frederick
Goding, Jr., George S.
Atyabi, Alanie
Schmidt, Siegmar
Dai, William
Dearden, Brian
Keenan, Desmond B.
Abrégé
An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p.ex. laryngoscopes, bronchoscopes
A61B 5/083 - Mesure du taux de métabolisme en utilisant un essai respiratoire, p.ex. mesure du taux de consommation d'oxygène
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
A61B 5/394 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG] spécialement adaptée pour l’électroglottographie ou l’électropalatographie
81.
Stimulator systems and methods for obstructive sleep apnea
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Suri, Harshit
Calderon, Joseph L.
Molnar, Gregory Frederick
Goding, Jr., George S.
Atyabi, Alanie
Schmidt, Siegmar
Dai, William
Dearden, Brian
Keenan, Desmond B.
Abrégé
An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p.ex. laryngoscopes, bronchoscopes
A61B 5/083 - Mesure du taux de métabolisme en utilisant un essai respiratoire, p.ex. mesure du taux de consommation d'oxygène
A61B 5/394 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG] spécialement adaptée pour l’électroglottographie ou l’électropalatographie
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Schmidt, Siegmar
Dai, William A.
Ng, Boon Khai
Abrégé
Pressure sensors having ring-tensioned membranes are disclosed. A tensioning ring is bonded to a membrane in a manner that results in the tensioning ring applying a tensile force to the membrane, flattening the membrane and reducing or eliminating defects that may have occurred during production. The membrane is bonded to the sensor housing at a point outside the tensioning ring, preventing the process of bonding the membrane to the housing from introducing defects into the tensioned portion of the membrane. A dielectric may be introduced into the gap between the membrane and the counter electrode in a capacitive pressure sensor, resulting in an improved dynamic range.
G01L 9/00 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pression; Transmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent
G01L 1/14 - Mesure des forces ou des contraintes, en général en mesurant les variations de la capacité ou de l'inductance des éléments électriques, p.ex. en mesurant les variations de fréquence des oscillateurs électriques
G01L 7/08 - Mesure de la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments mécaniques ou hydrauliques sensibles à la pression sous forme de jauges, élastiquement déformables du type à diaphragme élastique
G01L 9/12 - Mesure de la pression permanente, ou quasi permanente d’un fluide ou d’un matériau solide fluent par des éléments électriques ou magnétiques sensibles à la pression; Transmission ou indication par des moyens électriques ou magnétiques du déplacement des éléments mécaniques sensibles à la pression, utilisés pour mesurer la pression permanente ou quasi permanente d’un fluide ou d’un matériau solide fluent en faisant usage des variations de la capacité
G01L 19/04 - Moyens pour compenser les effets des variations de température
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Rodriguez, Saul
Han, Dianna (dan)
Istoc, Emil
Abrégé
A medical device of a medical system is configured for communicating with an external programmer over a wireless communications link. The medical device comprises a wireless communications module configured for receiving a first unencrypted version of a random number and a first encrypted version of the random number from the external programmer over the wireless communications link. The medical device further comprises control circuitry configured for performing an authentication procedure on the external programmer based on the first unencrypted version of the random number and the first encrypted version of the random number, and preventing the external programmer from commanding the medical device to perform an action unless the authentication procedure is successful.
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p.ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
H04L 69/40 - Dispositions, protocoles ou services de réseau indépendants de la charge utile de l'application et non couverts dans un des autres groupes de la présente sous-classe pour se remettre d'une défaillance d'une instance de protocole ou d'une entité, p.ex. protocoles de redondance de service, état de redondance de protocole ou redirection de service de protocole
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
H04L 67/141 - Configuration des sessions d'application
H04L 67/53 - Services réseau en utilisant des fournisseurs tiers de services
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
H04Q 9/00 - Dispositions dans les systèmes de commande à distance ou de télémétrie pour appeler sélectivement une sous-station à partir d'une station principale, sous-station dans laquelle un appareil recherché est choisi pour appliquer un signal de commande ou
H04W 12/04 - Gestion des clés, p.ex. par architecture d’amorçage générique [GBA]
G06F 21/62 - Protection de l’accès à des données via une plate-forme, p.ex. par clés ou règles de contrôle de l’accès
84.
Stimulator systems and methods for obstructive sleep apnea
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Suri, Harshit
Calderon, Joseph L.
Molnar, Gregory Frederick
Goding, Jr., George S.
Atyabi, Alanie
Schmidt, Siegmar
Dai, William
Dearden, Brian
Keenan, Desmond B.
Abrégé
An electrode lead comprises an electrically insulative cuff body and at least three axially aligned electrode contacts circumferentially disposed along the inner surface of the cuff body when in the furled state. The electrode contacts may be circumferentially disposed around a nerve, and an electrical pulse train may be delivered to the electrode contacts thereby stimulating the nerve to treat obstructive sleep apnea. The electrical pulse train may be one that pre-conditions peripherally located nerve fascicles to not be stimulated, while stimulating centrally located nerve fascicles. A feedback mechanism can be used to titrate electrode contacts and electrical pulse train to the patient. A sensor that is affixed to the case of a neurostimulator can be used to measure physiological artifacts of respiration, and a motion detector can be used to sense tapping of the neurostimulator to toggle the neurostimulator between an ON position and an OFF position.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p.ex. laryngoscopes, bronchoscopes
A61B 5/083 - Mesure du taux de métabolisme en utilisant un essai respiratoire, p.ex. mesure du taux de consommation d'oxygène
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
A61B 5/394 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG] spécialement adaptée pour l’électroglottographie ou l’électropalatographie
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Lee, Edward K. F.
Abrégé
A multiple output current stimulator circuit with fast turn on time is described. At least one pair of input side and output side transistors is arranged in a current mirror connected to a supply transistor by cascode coupling. The output side transistor supplies stimulation current to an electrode in contact with tissue. An operational amplifier connected to a reference voltage and to the output side transistor drives the supply transistor to maintain the voltage at the output side transistor equal to the reference voltage. The at least one pair of transistors includes multiple pairs of transistors whose output side transistors drive respective electrodes with stimulation currents. The stimulator determines the initiation and duration of stimulation current pulses supplied to each electrode. At circuit activation, large currents are generated which discharge capacitances in the output side transistors causing rapid output side transistor turn on.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
H03K 3/012 - Modifications du générateur pour améliorer le temps de réponse ou pour diminuer la consommation d'énergie
H03K 3/023 - Générateurs caractérisés par le type de circuit ou par les moyens utilisés pour produire des impulsions par l'utilisation d'amplificateurs différentiels ou des comparateurs, avec réaction positive interne ou externe
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian R.
Wolfe, James H.
Khemani, Manish
Abrégé
A charger including a class E power driver, a frequency-shift keying (“FSK”) module, and a processor. The processor can receive data relating to the operation of the class E power driver and can control the class E power driver based on the received data relating to the operation of the class E power driver. The processor can additionally control the FSK module to modulate the natural frequency of the class E power transformer to thereby allow the simultaneous recharging of an implantable device and the transmission of data to the implantable device. The processor can additionally compensate for propagation delays by adjusting switching times.
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
H02J 50/80 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique mettant en œuvre l’échange de données, concernant l’alimentation ou la distribution d’énergie électrique, entre les dispositifs de transmission et les dispositifs de réception
H02J 7/02 - Circuits pour la charge ou la dépolarisation des batteries ou pour alimenter des charges par des batteries pour la charge des batteries par réseaux à courant alternatif au moyen de convertisseurs
87.
Multiple implant communications with adjustable load modulation based on received signal amplitudes
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Lee, Edward K. F.
Suri, Harshit R.
Abrégé
A medical system and method of communicating between a telemetry controller and medical devices is provided. Coupling coefficients between a primary coil of the telemetry controller and secondary coils of the medical devices differ from each other. A primary carrier signal is applied to the primary coil, thereby respectively inducing secondary carrier signals on the secondary coils. An amplitude of the secondary carrier signal is measured on each of the secondary coils. The envelope of each secondary carrier signal is modulated in accordance with data, thereby inducing modulation of the envelope of the primary carrier signal for the implanted medical devices. The secondary carrier signal envelopes are modulated based on the measured amplitudes of the respective secondary carrier signals.
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
H04B 14/00 - Systèmes de transmission non caractérisés par le milieu utilisé pour la transmission
H04L 27/02 - Systèmes à courant porteur à modulation d'amplitude, p.ex. utilisant la manipulation par tout ou rien; Modulation à bande latérale unique ou à bande résiduelle
H04L 27/10 - Systèmes à courant porteur à modulation de fréquence, p.ex. utilisant une manipulation à décalage de fréquence
H04L 27/18 - Systèmes à courant porteur à modulation de phase, c. à d. utilisant une manipulation à décalage de phase
88.
SKIN PATCHES FOR SENSING OR AFFECTING A BODY PARAMETER
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian R.
Petrovich, John G.
Abrégé
Skin patch sensors for monitoring and/or affecting body parameters, with alignment, positioning and attachment using magnets. The repeated use of releasable adhesive layers to retain skin patch sensors on skin can cause skin irritation, which can be reduced by rotating a skin patch between attachment times around a magnetically coupled pivot point. Skin patch sensors can be configured with internal coils to inductively couple to external power transmitting and communications coils with solenoids in anti-Helmholtz configurations.
A61B 5/25 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet
H02J 50/10 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif
A61B 5/296 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électromyographie [EMG]
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
89.
Skin patches for sensing or affecting a body parameter
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian R.
Petrovich, John G.
Abrégé
Skin patch sensors for monitoring and/or affecting body parameters, with alignment, positioning and attachment using magnets. The repeated use of releasable adhesive layers to retain skin patch sensors on skin can cause skin irritation, which can be reduced by rotating a skin patch between attachment times around a magnetically coupled pivot point. Skin patch sensors can be configured with internal coils to inductively couple to external power transmitting and communications coils with solenoids in anti-Helmholtz configurations.
A61B 5/05 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/296 - Détection, mesure ou enregistrement de signaux bioélectriques ou biomagnétiques du corps ou de parties de celui-ci Électrodes bioélectriques à cet effet spécialement adaptées à des utilisations particulières pour l’électromyographie [EMG]
A61F 2/70 - Moyens d'actionnement ou de commande électriques
90.
SKIN PATCHES FOR SENSING OR AFFECTING A BODY PARAMETER
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Dearden, Brian R.
Petrovich, John G.
Abrégé
Skin patch sensors for monitoring and/or affecting body parameters, with alignment, positioning and attachment using magnets. The repeated use of releasable adhesive layers to retain skin patch sensors on skin can cause skin irritation, which can be reduced by rotating a skin patch between attachment times around a magnetically coupled pivot point. Skin patch sensors can be configured with internal coils to inductively couple to external power transmitting and communications coils with solenoids in anti-Helmholtz configurations.
H02J 50/10 - Circuits ou systèmes pour l'alimentation ou la distribution sans fil d'énergie électrique utilisant un couplage inductif
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Schmidt, Siegmar
Ng, Boon Khai
Abrégé
An electrode lead may comprise a flexible circuit that includes a planar dielectric substrate including an elongated lead substrate portion having opposing ends, an electrode carrying substrate portion disposed on one end of the lead substrate portion, and a connector substrate portion disposed on the other end of the lead substrate portion, wherein the lead substrate portion is pre-shaped into a three-dimensional structure. The flexible circuit may further include an electrically conductive trace extending from the connector substrate portion to the electrode carrying substrate portion, a first window formed in the connector substrate portion to expose the electrically conductive trace to form a connector pad, and a second window formed in the electrode carrying substrate portion to expose the electrically conductive trace to form an electrode pad. The electrode lead may further comprise a lead connector that incorporates the connector substrate portion.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/389 - Modalités, c. à d. méthodes diagnostiques spécifiques Électromyographie [EMG]
ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Jiang, Guangqiang
He, Tom
Abrégé
The various implementations described herein include a percutaneous port for promoting tissue in-growth around the percutaneous port. In one aspect, the percutaneous port includes a tubular structure having an outer surface, and a coil having an outer surface and comprised of a plurality of loops. Furthermore, at least a portion of the outer surface of the coil is joined to the outer surface of the tubular structure.
The Alfred E. Mann Foundation for Scientific Research (USA)
Inventeur(s)
Schulman, Joseph H.
Hankin, David L.
Abrégé
Biocompatible stiffness enhanced pliable electrically conductive filaments configured for contact with living tissue and electrical communication with such tissue. The pliability of the filaments allows the distal end of the filaments to remain at the original site of penetration into the tissue despite the movement of the tissue relative to their surrounding environment. To temporarily stiffen the filaments, a soluble stiffness enhancing coating is disposed over the filaments. The coating may be in the form of a liquid which dries to a solid state after being applied to the filaments and renders the filaments sufficiently rigid such that under appropriate force, the filaments are capable of penetrating into dense tissue. Once in place, the stiffness enhancing coating dissolves due to contact with body fluids, the filaments, in the absence of such a coating, return to their initial pliability.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Ng, Boon Khai
Calderon, Joseph L.
Abrégé
An electrode lead comprises a lead body, connector contacts affixed to the proximal end of the lead body, and a cuff body affixed to the distal end of the lead body. The cuff body is pre-shaped to transition from an unfurled state to a furled state, wherein the cuff body, when in the furled state has an inner surface for contacting a nerve and an overlapping inner cuff region and an outer cuff region. The electrode lead further comprise electrode contacts circumferentially disposed along the cuff body when in the furled state, such that at least one of the electrode contacts is located on the inner surface of the cuff body, and at least another of the electrode contacts is located between the overlapping inner and outer cuff regions. The electrode lead further comprises electrical conductors extending through the lead body respectively between the connector contacts and the electrode contacts.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Ng, Boon Khai
Calderon, Joseph L.
Abrégé
An electrode lead comprises a lead body, connector contacts affixed to the proximal end of the lead body, and a cuff body affixed to the distal end of the lead body. The cuff body is pre-shaped to transition from an unfurled state to a furled state, wherein the cuff body, when in the furled state has an inner surface for contacting a nerve and an overlapping inner cuff region and an outer cuff region. The electrode lead further comprise electrode contacts circumferentially disposed along the cuff body when in the furled state, such that at least one of the electrode contacts is located on the inner surface of the cuff body, and at least another of the electrode contacts is located between the overlapping inner and outer cuff regions. The electrode lead further comprises electrical conductors extending through the lead body respectively between the connector contacts and the electrode contacts.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Ng, Boon Khai
Calderon, Joseph L.
Abrégé
An electrode lead comprises a lead body, connector contacts affixed to the proximal end of the lead body, and a cuff body affixed to the distal end of the lead body. The cuff body is pre-shaped to transition from an unfurled state to a furled state, wherein the cuff body, when in the furled state has an inner surface for contacting a nerve and an overlapping inner cuff region and an outer cuff region. The electrode lead further comprise electrode contacts circumferentially disposed along the cuff body when in the furled state, such that at least one of the electrode contacts is located on the inner surface of the cuff body, and at least another of the electrode contacts is located between the overlapping inner and outer cuff regions. The electrode lead further comprises electrical conductors extending through the lead body respectively between the connector contacts and the electrode contacts.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61N 1/05 - Electrodes à implanter ou à introduire dans le corps, p.ex. électrode cardiaque
A61N 1/372 - Aménagements en relation avec l'implantation des stimulateurs
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Lee, Edward K.F.
Abrégé
A multiple output current stimulator circuit with fast turn on time is described. At least one pair of input side and output side transistors is arranged in a current mirror connected to a supply transistor by cascode coupling. The output side transistor supplies stimulation current to an electrode in contact with tissue. An operational amplifier connected to a reference voltage and to the output side transistor drives the supply transistor to maintain the voltage at the output side transistor equal to the reference voltage. The at least one pair of transistors includes multiple pairs of transistors whose output side transistors drive respective electrodes with stimulation currents. The stimulator determines the initiation and duration of stimulation current pulses supplied to each electrode. At circuit activation, large currents are generated which discharge capacitances in the output side transistors causing rapid output side transistor turn on.
A61N 1/36 - Application de courants électriques par électrodes de contact courants alternatifs ou intermittents pour stimuler, p.ex. stimulateurs cardiaques
H03K 3/012 - Modifications du générateur pour améliorer le temps de réponse ou pour diminuer la consommation d'énergie
H03K 3/023 - Générateurs caractérisés par le type de circuit ou par les moyens utilisés pour produire des impulsions par l'utilisation d'amplificateurs différentiels ou des comparateurs, avec réaction positive interne ou externe
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Ng, Boon Khai
Dai, William
Abrégé
An electrode lead comprises an elongated lead body, at least one lead connector terminal affixed to the proximal end of the lead body, and an electrically insulative cuff body affixed to the distal end of the lead body. The cuff body is configured for being circumferentially disposed around a nerve. The cuff body comprises cutouts, slits, a wrinkled portion, a thin stretchable portion, and/or a serpentine strap, which increases that increase the expandability of the cuff body when disposed around the nerve. The electrode lead further comprises at least one electrode contact affixed to the cuff body, and at least one electrical conductor extending through the lead body between the at least one lead connector terminal and the electrode contact(s). If the cuff body comprises cutouts or slits, the electrode lead can further comprise a thin stretchable film affixed to the cuff body over cutouts or slits.
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Lee, Edward K. F.
Suri, Harshit R.
Abrégé
A medical system and method of communicating between a telemetry controller and a plurality of medical devices implanted within a patient is provided. Communication links are respectively established between the telemetry controller and the implanted medical devices. The communication links are respectively amplitude modulated by the implanted medical devices at modulation levels using load modulation. Received signal strength indicators (RSSIs) of the amplitude modulated communication links for the implanted medical devices are measured. A variation of the RSSIs is decreased by modifying, based on the measured RSSIs, at least one modulation level at which the respective at least one communication link is amplitude modulated by the respective implanted medical device(s).
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH (USA)
Inventeur(s)
Lee, Edward K. F.
Suri, Harshit R.
Abrégé
A medical system and method of communicating between a telemetry controller and a plurality of medical devices implanted within a patient is provided. Communication links are respectively established between the telemetry controller and the implanted medical devices. The communication links are respectively amplitude modulated by the implanted medical devices at modulation levels using load modulation. Received signal strength indicators (RSSIs) of the amplitude modulated communication links for the implanted medical devices are measured. A variation of the RSSIs is decreased by modifying, based on the measured RSSIs, at least one modulation level at which the respective at least one communication link is amplitude modulated by the respective implanted medical device(s).