Abrégé

A majority of military casualties occur during the pre-hospital period. The cause of death is largely associated with massive traumatic bleeding that leads to organ damage due to sustained hypoxia. Currently, therapeutics are lacking at the point of injury to mitigate hypoxic damage and maintain the survivability of severe hemorrhage prior to reaching medical facilities. This invention addresses that by introducing a method of co-administering prolyl hydroxylase domain inhibitor (PHDi, MK-8617), anti-fibrinolytic agent (tranexamic acid), and bradykinin receptor antagonist (icatibant) as anti-hemorrhage agents in combination with resuscitation fluid treatment with colloid solution of 25% human albumin that has an advantage of relatively small volume requirement to maintain blood volume. In addition, a kit comprising anti-hemorrhage agents that can be easily carried to the battlefield is also provided here. The therapeutic application of those agents on or near the point of injury can stabilize hypoxia inducible factor-1 alpha and enhance blood clot formation, which improves the patient's cellular adaptation to hypoxia and reduce hemorrhage, and thus can decrease organ failure and increase the patient's survivability.

Classes IPC  ?

• A61K 35/19 - Plaquettes; Mégacaryocytes
• A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
• A61K 31/137 - Arylalkylamines, p.ex. amphétamine, épinéphrine, salbutamol, éphédrine
• A61K 31/437 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à six chaînons avec un azote comme seul hétéro-atome d'un cycle condensés en ortho ou en péri avec des systèmes hétérocycliques le système hétérocyclique contenant un cycle à cinq chaînons ayant l'azote comme hétéro-atome du cycle, p.ex. indolizine, bêta-carboline
• A61K 31/4418 - Pyridines non condensées; Leurs dérivés hydrogénés ayant un carbocycle lié directement à l'hétérocycle, p.ex. cyproheptadine
• A61K 31/472 - Isoquinoléines non condensées, p.ex. papavérine
• A61K 31/506 - Pyrimidines; Pyrimidines hydrogénées, p.ex. triméthoprime non condensées et contenant d'autres hétérocycles
• A61K 31/513 - Pyrimidines; Pyrimidines hydrogénées, p.ex. triméthoprime ayant des groupes oxo liés directement à l'hétérocycle, p.ex. cytosine
• A61K 31/5377 - 1,4-Oxazines, p.ex. morpholine non condensées et contenant d'autres hétérocycles, p.ex. timolol
• A61K 35/14 - Sang; Sang artificiel
• A61K 35/16 - Plasma sanguin; Sérum sanguin
• A61K 35/18 - Erythrocytes
• A61K 38/04 - Peptides ayant jusqu'à 20 amino-acides dans une séquence entièrement déterminée; Leurs dérivés
• A61K 38/095 - Oxytocines; Vasopressines; Peptides apparentés
• A61K 38/36 - Facteurs de coagulation sanguine ou de fibrinolyse
• A61K 38/38 - Albumines
• A61K 47/26 - Hydrates de carbone, p.ex. polyols ou sucres alcoolisés, sucres aminés, acides nucléiques, mono-, di- ou oligosaccharides; Leurs dérivés, p.ex. polysorbates, esters d’acide gras de sorbitan ou glycyrrhizine
• A61P 7/04 - Antihémorragiques; Profacteurs de coagulation; Agents hémostatiques; Agents antifibrinolytiques

Abrégé

A recoilless gun system, comprising a gun assembly and associated ammunition for use with the gun assembly employs an integral barrel and a rear inserted ammunition round. The recoilless gun system may combine a laser initiator and a polymer cased ammunition to enable a lightweight system. In such embodiments, the cartridge case is made from a polymer that resists high pressure before extruding into small gaps.

Classes IPC  ?

• F41A 1/10 - Canons sans recul, c. à d. armes à feu munies d'un système de propulsion qui ne produit pas de recul utilisant un projectile antagoniste pour équilibrer le recul

Abrégé

Ways to provide information via dynamic user interfaces including Dynamic InfoGraphics (DIG) are described. DIG representations may include various elements, such as text, icons and other graphics, tags, links, etc. and may be implemented via various types of displays or operating environments. Users may include, for example, pilots, soldiers, commanders, drivers, game players, etc. Information provided via DIG may include, for instance, data received from various types of sensors, communications received from other parties or resources, calculated or otherwise determined information (e.g., predictions associated with artificial intelligence (AI) resources such as autonomous or semi-autonomous intelligent agents), and/or other appropriate information (e.g., user inputs). The received information may be applied to one or more DIG representations or templates. AI features may be used to predict future actions, paths, goals or targets, etc. The DIG representation(s) may be updated as updated sensor information is received and/or predictions are generated.

Classes IPC  ?

• G06F 3/048 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI]
• G06F 3/0484 - Techniques d’interaction fondées sur les interfaces utilisateur graphiques [GUI] pour la commande de fonctions ou d’opérations spécifiques, p.ex. sélection ou transformation d’un objet, d’une image ou d’un élément de texte affiché, détermination d’une valeur de paramètre ou sélection d’une plage de valeurs

Abrégé

Shaped charge devices, systems, and related methods of use. A housing sheet is configurable to form at least part of a shaped charge enclosure enclosing a shaped charge and biasing an explosion in a desired direction. The housing sheet can include one or more incisions in at least one surface thereof. The housing sheet can have at least one connection mechanism integrally formed therein, and the housing sheet can be configurable to form a plurality of sizes of shaped charge housing portions. The housing sheet can also provide for forming a plurality of dimensions of the shaped charge enclosure.

Classes IPC  ?

• F42B 1/028 - Charges creuses ou profilées caractérisées par la forme du revêtement
• F42B 1/036 - Procédés de fabrication de ces charges
• F42B 3/08 - Cartouches de sautage, c. à d. enveloppes avec explosif avec des cavités dans la charge, p.ex. cartouches de sautage à charge creuse

Abrégé

A method for controlling a fuel reformation reaction in a fuel reformation reactor is provided. Furthermore, a non-transitory computer-readable storage medium is provided, which is configured to store a program for controlling a fuel reformation reaction in a fuel reformation reactor. In addition, a fuel reformation system for controlling a fuel reformation reaction is provided, which includes a fuel reformation reactor and a control unit.

Classes IPC  ?

• C01B 3/36 - Production d'hydrogène ou de mélanges gazeux contenant de l'hydrogène par réaction de composés organiques gazeux ou liquides avec des agents gazéifiants, p.ex. de l'eau, du gaz carbonique, de l'air par réaction d'hydrocarbures avec des agents gazéifiants avec l'oxygène ou des mélanges contenant de l'oxygène comme agents gazéifiants

Abrégé

In one embodiment, an enclosure device for a printed circuit board (PCB) comprises: an enclosure wall structure including therein a heater exchanger, a pipe to direct a cooling liquid through the heat exchanger, and a ducting to direct a gas through the heat exchanger to be cooled by the cooling liquid; and a PCB space adjacent to a portion of the enclosure wall structure for receiving the PCB. The ducting includes a downstream duct disposed downstream of the heat exchanger and extending through the portion of the enclosure wall structure adjacent to the PCB space to direct the cooled gas to the portion of the enclosure wall structure adjacent to the PCB space.

Classes IPC  ?

• H05K 7/20 - Modifications en vue de faciliter la réfrigération, l'aération ou le chauffage
• G06F 1/18 - Installation ou distribution d'énergie
• G06F 1/20 - Moyens de refroidissement
• H05K 1/02 - Circuits imprimés - Détails

Abrégé

An apparatus for guiding fish through a body of water having a water flow includes one or more hydrofoil element oriented in the body of water to produce an asymmetric flow field that has a fast, low turbulent flow on one side of the element and a slow, high turbulent flow on the other side of the element. Positively rheotactic fish have a preference for one side versus the other and so are guided in a desired direction. Systems and method that utilize the apparatus can be used to guide fish away from infrastructure such as dams, locks, levees, flood weirs, and other diversion points.

Classes IPC  ?

• E02B 8/08 - Passages à poissons; Passages pour radeaux ou bateaux

Abrégé

The present invention is directed to aqueous solid state electrolytes that comprise a fluoride additive to stabilize the interface between the anode and aqueous electrolyte. The present invention is also directed to methods of making the solid state electrolyte materials and methods of using the solid state electrolyte materials in batteries and other electrochemical technologies.

Classes IPC  ?

• H01M 10/0567 - Matériaux liquides caracterisés par les additifs
• H01M 4/131 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif Électrodes pour accumulateurs à électrolyte non aqueux, p.ex. pour accumulateurs au lithium; Leurs procédés de fabrication Électrodes à base d'oxydes ou d'hydroxydes mixtes, ou de mélanges d'oxydes ou d'hydroxydes, p.ex. LiCoOx
• H01M 4/134 - PROCÉDÉS OU MOYENS POUR LA CONVERSION DIRECTE DE L'ÉNERGIE CHIMIQUE EN ÉNERGIE ÉLECTRIQUE, p.ex. BATTERIES Électrodes Électrodes composées d'un ou comprenant un matériau actif Électrodes pour accumulateurs à électrolyte non aqueux, p.ex. pour accumulateurs au lithium; Leurs procédés de fabrication Électrodes à base de métaux, de Si ou d'alliages
• H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages
• H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p.ex. LiMn2O4 ou LiMn2OxFy
• H01M 4/583 - Matériau carboné, p.ex. composés au graphite d'intercalation ou CFx
• H01M 4/66 - Emploi de matériaux spécifiés
• H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium

Abrégé

The invention relates to a game simulating research and development of a product. The game may comprise a central board, function cards, form cards, a player board and HR Meeple. The central board may comprise an endless outside track. The game may comprise three phases. A concept phase may involve: creating a product requirements document; recoding the product requirements document; collecting starting resources; building an initial team; and assigning initial tasking. A development phase may comprise: following turn and round rules; completing player actions; and assigning HR units to a facility. A prototyping phase wherein a final product is made.

Classes IPC  ?

• A63F 3/00 - Jeux se jouant sur une table; Jeux de hasard
• A63F 1/04 - Jeux de cartes combinés à d'autres jeux
• A63F 13/822 - Jeux de stratégie; Jeux de rôle

Abrégé

The present disclosure is directed to monoclonal antibodies, or antigen-binding fragments thereof, that bind to coronavirus spike proteins, including the spike protein of SARS-CoV-2. These antibodies demonstrate high affinity binding to epitopes on the coronavirus spike protein and/or broad cross-reactivity to the spike protein of various coronaviruses. Compositions comprising the anti-coronavirus antibodies, nucleic acids encoding for the antibodies, recombinant expression vectors, and host cells are also disclosed. The present disclosure is also directed to methods of diagnosing, preventing or treating coronavirus infections, including infections or disease caused by SARS-CoV-2.

Classes IPC  ?

• C07K 16/10 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de virus de virus à ARN
• A61P 37/04 - Immunostimulants

Abrégé

A 3D bioprinter having a visible light source to photocure biomaterial is disclosed. The 3D bioprinter prints visible light-curable biomaterial along with viable cells, and visible light photocures the biomaterial while maintaining cell viability. Visible light 3D bioprinter systems and methods of printing are further disclosed.

Classes IPC  ?

• C12M 1/26 - Inoculateur ou échantillonneur
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 30/00 - Appareils pour la fabrication additive; Leurs parties constitutives ou accessoires à cet effet
• B33Y 70/00 - Matériaux spécialement adaptés à la fabrication additive
• C12M 1/12 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens de stérilisation, filtration ou dialyse
• C12N 11/098 - Enzymes ou cellules microbiennes immobilisées sur ou dans un support organique le support étant un polymère synthétique formé en présence des enzymes ou des cellules microbiennes

Abrégé

The present invention is directed to a passive outdoor air sampler device with various screen types and materials for efficient collection of air particles. Screens are used as a collection surface for aerosolized particles. The air sampler is suitable for long-term use in different outdoor settings with no power requirements.

Classes IPC  ?

• G01N 15/06 - Recherche de la concentration des suspensions de particules
• G01N 1/22 - Dispositifs pour prélever des échantillons à l'état gazeux
• B01D 46/00 - Filtres ou procédés spécialement modifiés pour la séparation de particules dispersées dans des gaz ou des vapeurs
• F24F 8/10 - Traitement, p.ex. purification, de l'air fourni aux locaux de résidence ou de travail des êtres humains autrement que par chauffage, refroidissement, humidification ou séchage par séparation, p.ex. par filtrage

Abrégé

Benzoxazine compounds, methods of making them, polymers made therefrom and methods of polymerizing the benzoxazines. These renewable benzoxazine monomers and polymers that utilize the variety of building blocks found in renewable plant biomass, demonstrate excellent processability and large temperature windows for processing of resin systems.

Classes IPC  ?

• C07D 413/06 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques
• C07D 307/52 - Radicaux substitués par des atomes d'azote ne faisant par partie d'un radical nitro 
• C07D 413/14 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant au moins trois hétérocycles
• C08G 73/02 - Polyamines

Abrégé

Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I): Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I): Methods of prevention of symptomatic malaria in a malaria-naïve, G6PD-normal human subject comprising administering to the human subject a compound of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I): A compound of Formula (I) can be administered prior to potential exposure of a species of Plasmodium, during potential exposure of a species of Plasmodium, and after potential exposure of a species of Plasmodium. The methods of the invention also pertains to kits comprising specific doses of Formula (I), a pharmaceutically acceptable salt thereof, or pharmaceutical composition comprising a compound of Formula (I), and instructions for administration of dosing quantity and frequency. The methods of the invention also pertain to determining doses of Formula (I) that meet the general regulatory requirement for a drug to be efficacious in the prevention of malaria in malaria-naïve subjects. The methods of the invention further pertain to using the described algorithm to derive dosing regimens which can provide protection against symptomatic malaria in malaria-naïve, G6PD-normal subjects.

Classes IPC  ?

• A61K 31/4706 - 4-Aminoquinoléines; 8-Aminoquinoléines, p.ex. chloroquine, primaquine
• A61P 33/06 - Antipaludéens
• C07D 215/40 - Atomes d'azote liés en position 8

Abrégé

Provided are cathepsin inhibitor compounds and pharmaceutically acceptable salts thereof, and combinations thereof, for use in the treatment or prophylaxis of viral disease in an animal.

Classes IPC  ?

• A61K 31/55 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p.ex. azélastine, pentylènetétrazole
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p.ex. composés antiphlogistiques et pour le cœur 
• A61P 31/14 - Antiviraux pour le traitement des virus ARN

Abrégé

An apparatus and method for detecting an analyte of interest using paper spray mass spectrometry includes a spray material; a sample on the spray material including an enzyme of interest; a solvent to hydrate the sample, promote enzymatic activity, and extract analytes of interest from the sample; a substrate specific to the enzyme of interest, wherein any of the spray material and the solvent includes the substrate; a voltage source to apply a voltage to the spray material to create charged droplets of a mixture containing the sample; and a mass spectrometer to perform spectrometry on the droplets to perform any of: identify the analytes of interest in the sample; and measure a level of inhibition in any enzymes contained in the sample.

Classes IPC  ?

• C12Q 1/46 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir une hydrolase une estérase une cholinestérase
• H01J 49/04 - Dispositions pour introduire ou extraire les échantillons devant être analysés, p.ex. fermetures étanches au vide; Dispositions pour le réglage externe des composants électronoptiques ou ionoptiques
• H01J 49/16 - Sources d'ions; Canons à ions utilisant une ionisation de surface, p.ex. émission thermo-ionique ou photo-électrique
• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

A power generation assembly for a weapon system converts waste energy from a firing event to electric power. The power generation assembly directs expanding burning propellant gasses within the weapon system into a turbine array to generate electric current. The electric current is rectified to trickle charge a battery bank which then powers the weapon system.

Classes IPC  ?

• F41A 13/10 - Ventilateurs ou turbines pour l'évacuation des gaz ou le refroidissement des armes à feu, p.ex. actionnés par la pression des gaz de combustion ou le recul
• F41A 19/08 - Systèmes de mise à feu mécaniques actionnés par un cordon tire-feu

Abrégé

A fired cartridge case collector includes a base having a collection post. The collection post of the base is configured to collect and suspend a fired cartridge case without causing contact to an exterior surface of the fired cartridge case. The fired cartridge case collector also includes a protective envelope having a first end and a second end opposite the first end, wherein the first end of the protective envelope is configured to be removably secured to the base. The protective envelope is configured to prevent contact between an interior surface of the protective envelope and the exterior surface of the fired cartridge case while the protective envelope is removably secured to the base. The fired cartridge case collector permits individual collection, packaging, and non-contact storage of fired gun cartridge cases thereby preserving any DNA or other evidence that may be present.

Classes IPC  ?

• F42B 39/22 - Blocage des munitions dans leurs emballages de transport
• G01N 1/04 - Dispositifs pour prélever des échantillons à l'état solide, p.ex. par coupe à l'outil

Abrégé

A portable filtration system is described. The system may comprise: a mixing portion, comprising: a pump adaptor and a contaminant regulator. The pump adaptor may comprise: an upper plate, a lower plate, and a screen. The screen may axially extend between the upper and lower plates, wherein the upper plate, the lower plate, and the screen define a channel of a mixing chamber. The contaminant regulator may comprise a through-passage coupled to the upper plate, wherein the through-passage is in fluid communication with the mixing chamber.

Classes IPC  ?

• B01D 61/02 - Osmose inverse; Hyperfiltration
• B01D 61/12 - Commande ou régulation
• B01D 65/02 - Nettoyage ou stérilisation de membranes
• C02F 1/00 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout
• C02F 1/44 - Traitement de l'eau, des eaux résiduaires ou des eaux d'égout par dialyse, osmose ou osmose inverse
• B01D 61/10 - Accessoires; Opérations auxiliaires

Abrégé

The present invention is directed to aqueous solid polymer electrolytes that comprise a lithium salt and battery cells comprising the same. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies.

Classes IPC  ?

• H01M 10/0565 - Matériaux polymères, p.ex. du type gel ou du type solide
• H01M 10/0525 - Batteries du type "rocking chair" ou "fauteuil à bascule", p.ex. batteries à insertion ou intercalation de lithium dans les deux électrodes; Batteries à l'ion lithium
• H01M 4/58 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs de structures polyanioniques, p.ex. phosphates, silicates ou borates
• H01M 4/505 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'oxydes ou d'hydroxydes inorganiques de manganèse d'oxydes ou d'hydroxydes mixtes contenant du manganèse pour insérer ou intercaler des métaux légers, p.ex. LiMn2O4 ou LiMn2OxFy
• H01M 4/38 - Emploi de substances spécifiées comme matériaux actifs, masses actives, liquides actifs d'éléments simples ou d'alliages

Abrégé

A band track including a band having an inner surface, an outer surface, a first side face, and a second side face; a plurality of teeth extending from the inner surface and spaced apart circumferentially around the inner surface; a plurality of lugs extending from the outer surface and each spaced a distance apart circumferentially around the outer surface; a plurality of living hinges defined within the band circumferentially between each of the plurality of teeth; and at least one fiber-reinforcement disposed circumferentially within a neutral plane of the plurality of living hinges and a method of making the same.

Classes IPC  ?

• B62D 55/24 - Chenilles du type à flexibilité totale, p.ex. à courroies de caoutchouc
• B33Y 10/00 - Procédés de fabrication additive
• B33Y 50/02 - Acquisition ou traitement de données pour la fabrication additive pour la commande ou la régulation de procédés de fabrication additive
• B62D 55/28 - Eléments ou maillons en contact avec le sol démontables

Abrégé

A sealable sampling container includes a vessel having a bottom and walls upwardly extending therefrom and terminating in a sealing surface, the bottom and the walls defining a volume within the open top container. A gasket is configured to engage with the sealing surface of the vessel and a lid is configured to engage with the gasket at the sealing surface and lock to the vessel. A sampling port is affixed to one side of the vessel or the lid, the sampling port providing fluid communication between the volume within the open top container and an external environment. The sealable sampling container safely stores volatile chemical vapors and enables training on use of chemical detection equipment without resort to ventilation hoods or the use of respiratory protection equipment.

Classes IPC  ?

• G01N 1/22 - Dispositifs pour prélever des échantillons à l'état gazeux
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
• G09B 19/00 - Enseignement non couvert par d'autres groupes principaux de la présente sous-classe
• G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes

Abrégé

A modular satellite chassis includes frame rails having at least two front frame rails and two back frame rails. Transverse parallel ribs are disposed on the interiors of the front and back frame rails. The ribs on the front frame rails correspond in location to one another and to the ribs on the back frame rails. Each rib has a central longitudinal axis and a narrow first slot disposed along the central longitudinal axis. The ribs are spaced apart by wider second slots. Trays are slidingly received by the second slots on the front frame rails and the corresponding second slots on the back frame rails. A left side panel is connected to an outside of one of the front frame rails and one of the back frame rails. A right side panel is connected to an outside of the other front frame rail and the other back frame rail.

Classes IPC  ?

• H05K 7/14 - Montage de la structure de support dans l'enveloppe, sur cadre ou sur bâti
• B64G 1/10 - Satellites artificiels; Systèmes de tels satellites; Véhicules interplanétaires
• B64G 1/22 - Parties de véhicules spatiaux ou équipements spécialement destinés à être fixés dans ou sur ces véhicules

Abrégé

An in vitro model of an in vivo gastrointestinal tract including an in vitro model of an in vivo small intestine including a plurality of fermentation vessels and an in vitro model of an in vivo large intestine including a plurality of fermentation vessels is provided. A method of simulating a biotransformation of food product through the human digestive tract using an in vitro model of an in vivo gastrointestinal tract is provided.

Classes IPC  ?

• C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
• C12M 3/06 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus avec des moyens de filtration, d'ultrafiltration, d'osmose inverse ou de dialyse
• C12N 5/071 - Cellules ou tissus de vertébrés, p.ex. cellules humaines ou tissus humains
• C12M 3/00 - Appareillage pour la culture de tissus, de cellules humaines, animales ou végétales, ou de virus
• C12M 1/40 - Appareillage spécialement destiné à l'utilisation d'enzymes libres, immobilisées ou liées à un support, p.ex. appareils contenant un lit fluidisé d'enzymes immobilisées
• C12M 1/36 - Appareillage pour l'enzymologie ou la microbiologie comportant une commande sensible au temps ou aux conditions du milieu, p.ex. fermenteurs commandés automatiquement
• C12M 1/34 - Mesure ou test par des moyens de mesure ou de détection des conditions du milieu, p.ex. par des compteurs de colonies
• G01N 33/50 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique
• C12M 1/02 - Appareillage pour l'enzymologie ou la microbiologie avec des moyens d'échange de chaleur

Abrégé

The present invention generally relates to the use of extracellular vesicles derived from cardiosphere-derived cells (CDC-EVs) as an anti-shock therapeutic. For instance, the present invention relates to a method of using CDC-EVs to treat polytrauma associated with coagulopathy and hemorrhagic shock in a subject in need thereof, wherein the lactate, glucose and/or creatinine levels in the subject are decreased upon being treated with a therapeutically effective amount of CDC-EVs. The results presented herein are of great relevance to the development of EV products for use in combat casualty care, as the studies presented herein show that CDC-EVs have the potential to be an anti-shock therapeutic if administered immediately after injury involving trauma associated with hemorrhagic shock and/or coagulopathy.

Classes IPC  ?

• A61K 35/34 - Muscles; Cellules musculaires lisses; Cœur; Cellules souches cardiaques; Myoblastes; Myocytes; Cardiomyocytes
• A61K 9/127 - Liposomes
• A61P 7/04 - Antihémorragiques; Profacteurs de coagulation; Agents hémostatiques; Agents antifibrinolytiques

Abrégé

Disclosed herein are immunogenic compositions for preventing or treating infection with filarial parasites and biomarkers for diagnosing infection with filarial parasites.

Classes IPC  ?

• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• C07K 16/18 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains
• C07K 14/435 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant d'humains
• A61P 33/10 - Anthelmintiques
• G01N 33/53 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet

Abrégé

Apparel that is adjustable. For example, in one embodiment, the apparel is provided that includes a torso. The torso includes a front, a back, a first side connecting the front to the back, a second side connecting the front to the back, a bottom, and a top. A plurality of shell fabric portions is on the torso. Each portion in the plurality of portions of shell fabric is adapted to receive an elastomeric member. Bunched fabric is on the first side and second side of the torso. Pleats are on the front of the torso. A centrally located flap is on the torso and has a longitudinal axis that is substantially vertical. Sleeves are connected to the torso. A first zipper track is located on the bottom of the torso. Pants may include a second zipper track adapted to mate with the first zipper track and secure the pants to the torso.

Classes IPC  ?

• A41D 13/02 - Combinaisons de travail ou de sport
• A41D 1/06 - Pantalons
• A41D 3/00 - Vêtements extérieurs

Abrégé

Various embodiments are described that relate to failure determination for an integrated circuit. An integrated circuit can be tested to determine if the integrated circuit is functioning properly. The integrated circuit can be subjected to a specific radiation such that the integrated circuit produces a response. This response can be compared against an expected response to determine if the response matches the expected response. If the response does not match the expected response, then the integrated circuit fails the test. If the response matches the expected response, then the integrated circuit passes the test.

Classes IPC  ?

• G01R 31/311 - Test sans contact utilisant des rayonnements électromagnétiques non ionisants, p.ex. des rayonnements optiques de circuits intégrés
• G01R 31/265 - Test sans contact
• G01R 31/3185 - Reconfiguration pour les essais, p.ex. LSSD, découpage
• G01R 31/28 - Test de circuits électroniques, p.ex. à l'aide d'un traceur de signaux

Abrégé

A nucleic acid vaccine composition comprising one or more of a plasmid-based nucleic acid vaccine and immunotherapy, as well as a lipid formulation, is provided. In addition, the present invention provides a method of enhancing the potency of plasmid-based DNA vaccines and immunotherapies, by formulating a vaccine and/or immunotherapy in a lipid formulation, which is stable when refrigerated or stored frozen, is then delivered to a vaccinee by either needle/syringe, jet injection, or microneedles. The lipid formulation of the present invention comprises one or more lipid excipients selected from 1,2-Distearoyl-sn-glycero-3-phosphocholine, Cholest-5-en-3β-ol, 1,2-Dimyristoyl-rac-glycero-3-methylpolyoxyethlene, and or more symmetric ionizable cationic lipids. The present invention increases vaccine potency dramatically. It was unexpectedly discovered that the level of immunogen, or immune response molecules, produced in vivo is increased (versus administering merely the vaccine or immunotherapy) and, in the case of a vaccine immunogen, the immune response is enhanced.

Classes IPC  ?

• A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p.ex. par les adjuvants chimiques
• A61K 39/12 - Antigènes viraux
• A61K 39/275 - Poxviridae, p.ex. Avipoxvirus
• C12N 7/00 - Virus, p.ex. bactériophages; Compositions les contenant; Leur préparation ou purification

Abrégé

A remote weapon station (RWS) system for an unmanned ground vehicle (UGV) includes a dedicated weapon, multi-axis gimbal and ammunition handling capabilities with all operations functioning remotely and wirelessly. The RWS system is a gas powered, or self-powered, belt fed, rotating bolt lock weapon. In addition, the RWS is man-portable and air-droppable as the major subsystems may be latched together in the field without tooling or needing to make electrical connections.

Classes IPC  ?

• F41A 19/08 - Systèmes de mise à feu mécaniques actionnés par un cordon tire-feu
• F41A 9/34 - Alimentation en munitions par bandes-chargeurs à partir de magasins
• F41A 9/37 - Alimentation d'une même arme avec plusieurs types de munitions; Alimentation par les deux côtés
• F41A 7/06 - Dispositifs de réarmement des mitrailleuses, p.ex. à commande manuelle actionnés par des moyens électriques
• F41A 25/00 - Supports d'armes à feu permettant le recul ou le retour en batterie, p.ex. berceaux; Freins ou amortisseurs des tubes d'arme
• F41A 27/00 - Supports d'armes à feu permettant le pointage en hauteur ou en direction, p.ex. affûts
• F41A 19/12 - Gâchettes; Leur montage
• F41A 25/14 - Systèmes à ressort du type à ressort à boudin réglables
• F41A 19/58 - Mécanismes de mise à feu électriques

Abrégé

A communication system provides multimedia communications within and between armored ground combat vehicles (GCVs). The system includes client computers within the armored GCVs providing distributed and interconnected multimedia communications among the client computers. The multimedia communication may include a one-to-one communication, a text communication to a group, an audio communication to a group, or a video communication to a group. Logic providing the distributed and interconnected multimedia communications is not located at a single client computer. The client computers display graphical user interfaces (GUIs) enabling soldiers to select parameters of the communication system with some GUIs providing presence discovery among the armored GCVs. One of the plurality of client computers acts as an origination station and other client computers may be configured as receiving communication station(s). The origination communication station may transmit digital communication data to the receiving communication station(s).

Classes IPC  ?

• H04L 41/22 - Dispositions pour la maintenance, l’administration ou la gestion des réseaux de commutation de données, p.ex. des réseaux de commutation de paquets comprenant des interfaces utilisateur graphiques spécialement adaptées [GUI]
• H04L 67/12 - Protocoles spécialement adaptés aux environnements propriétaires ou de mise en réseau pour un usage spécial, p.ex. les réseaux médicaux, les réseaux de capteurs, les réseaux dans les véhicules ou les réseaux de mesure à distance
• H04W 4/10 - Services de messagerie instantanée vocale ou de messagerie sur appel
• H04L 69/326 - Protocoles de communication intra-couche entre entités paires ou définitions d'unité de données de protocole [PDU] dans la couche transport [couche OSI 4]
• H04L 65/60 - Diffusion en flux de paquets multimédias

Abrégé

A small lightweight weapon system for integration into an unmanned aerial vehicle comprises a weapon operating group which utilizes blowback operation to fire a full-powered centerfire rifle ammunition. An operating rod of the weapon operating group has an axis of translation offset from the longitudinal axis of the barrel thereby creating a moment couple on the system. A motor assembly controls the operation of the weapon operating group. Through a gear train, actuation of the motor assembly lifts a sear against a return torsion spring, which holds the operating group back when not firing. The gear train comprises a one way flywheel disconnect to increase the torque of the direct current motor and overcome the force of the torsion spring. Intelligent motor commutation and burst control are achieved through an encoder and software package.

Classes IPC  ?

• F41A 7/08 - Mécanismes d'entraînement des armes à feu à moteur externe, c. à d. mécanismes d'entraînement pour déplacer le bloc de culasse pendant le tir automatique en utilisant une force externe
• F41A 23/02 - Supports sans roues
• F41A 9/51 - Impulseurs, c. à d. moteurs commandés de l'extérieur
• F41A 19/31 - Mécanismes de gâchette
• F41A 19/12 - Gâchettes; Leur montage
• B64C 39/02 - Aéronefs non prévus ailleurs caractérisés par un emploi spécial
• B64U 101/00 - Véhicules aériens sans pilote spécialement adaptés à des utilisations ou à des applications spécifiques

Abrégé

The disclosed subject matter relates to relate to fibers, textiles, fabrics, clothing and methods that are retroreflective including fibers having a hollow sheath that is filled with retroreflective particles.

Classes IPC  ?

• G02B 5/12 - Réflecteurs reflex
• D01F 8/04 - Filaments, ou similaires, faits par l’homme, conjugués, c. à d. à plusieurs composants; Leur fabrication à partir de polymères synthétiques

Abrégé

This disclosure provides an assay and method for evaluating platelet function by measuring clot retraction in a grooved assay well using light transmittance in a low-volume, micro-plate formatted assay. The method takes advantage of the ability of platelets to draw the fibrin clot toward one side of the microplate well through an optical light path with readings recorded by a microplate reader. The method is rapid, tractable, has high precision, and yields time-series data that is quantitative. This allows clinicians and transfusion medicine practitioners to perform high throughput platelet function testing in patient samples and in blood/platelet products. Clot retraction serves as a functional biomarker to determine platelet function by performing the assay in a vessel that is scored to form a groove in which clot retraction occurs. Multiple samples can be tested simultaneously, and optionally an algorithm can be used to extract relevant parameters from the data.

Classes IPC  ?

• G01N 33/86 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir le temps de coagulation du sang
• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes

Abrégé

Camouflage patterns on a substrate such as a fabric comprise in a first aspect a substrate having a camouflage pattern with a set of intermixed colored blotches thereon, the colors of the set of intermixed colored blotches being selected from a group of colors comprising an Olive 527 color, a Dark Green 528 color, a Tan 525 color, a Brown 529 color, a Bark Brown 561 color and a Dark Cream 559 color. In another aspect the colors of the set of intermixed colored blotches being selected from a group of colors comprising an Olive 527 color, a Dark Green 528 color, a Light Sage 560 color, a Tan 525 color, a Brown 529 color, a Bark Brown 561 color and a Dark Cream 559 color.

Classes IPC  ?

• F41H 3/02 - Dispositifs couvrants, p.ex. écrans, filets
• F41H 3/00 - Camouflage, c. à d. moyens ou procédés de dissimulation ou de simulation
• B32B 5/00 - Produits stratifiés caractérisés par l'hétérogénéité ou la structure physique d'une des couches
• A41D 31/02 - Matériaux stratifiés
• A41D 29/00 - Uniformes; Parties ou accessoires d'uniformes
• D03D 1/00 - Tissus conçus pour faire des articles particuliers
• A41D 13/00 - Vêtements protecteurs de travail ou de sport, p.ex. blouses de chirurgien ou vêtements protégeant des coups ou des chocs

Abrégé

Various embodiments are described that relate to random noise addition to a communication. A first secure network can employ a first encryption scheme and a second secure network can employ a second encryption scheme. In order to communicate between the first secure network and the second secure network such that the schemes are not decipherable, random noise can be added to a communication designated to transfer from the first secure network to the second secure network.

Classes IPC  ?

• H04K 1/00 - Communications secrètes
• H04W 12/03 - Protection de la confidentialité, p.ex. par chiffrement

Abrégé

A tongue blade (retractor) with fenestrated suction ports along the length of the blade to remove (suction) smoke, fluid and/or particulate from the oral cavity during surgery (e.g. tonsillectomy, adenoidectomy, oral cavity/tongue/airway procedures). This blade can connect to routine mouth retractors and commonly available suction tubing. It has a groove along the length of the blade to accommodate endotracheal tubes for stabilization and to minimize pressure against the tongue during retraction.

Classes IPC  ?

• A61B 17/02 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets Écarteurs
• A61B 1/267 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments pour les voies respiratoires, p.ex. laryngoscopes, bronchoscopes
• A61B 1/015 - Commande de l'alimentation en fluide ou de l'évacuation de fluide
• A61B 1/00 - Instruments pour procéder à l'examen médical de l'intérieur des cavités ou des conduits du corps par inspection visuelle ou photographique, p.ex. endoscopes; Dispositions pour l'éclairage dans ces instruments

Abrégé

3Br.

Classes IPC  ?

• B01D 46/00 - Filtres ou procédés spécialement modifiés pour la séparation de particules dispersées dans des gaz ou des vapeurs
• B01D 29/52 - Filtres à éléments filtrants stationnaires pendant la filtration, p.ex. filtres à aspiration ou à pression, non couverts par les groupes ; Leurs éléments filtrants à plusieurs éléments filtrants caractérisés par leur agencement relatif montés en parallèle
• B01D 37/02 - Revêtement préalable des éléments filtrants ou de la substance filtrante; Addition d'adjuvants de filtration au liquide à filtrer
• B01D 46/56 - Filtres ou procédés spécialement modifiés pour la séparation de particules dispersées dans des gaz ou des vapeurs avec plusieurs éléments filtrants, caractérisés par leur disposition relative
• C08L 67/06 - Polyesters non saturés

Abrégé

Disclosed herein are shark-derived antibodies and binding molecules with high binding affinity for SARS-CoV-2 coronavirus and the use thereof. Some of the shark-derived antibodies and binding molecules also demonstrate cross-reactivity with and neutralization of other related sarbecoviruses. The complementarity determining region (CDR) sequences and binding characteristics for these antibodies and binding molecules are provided. Also disclosed are the use of these antibodies and binding molecules to detect SARS-CoV-2 coronavirus or other related sarbecoviruses or to prevent or treat SARS-CoV-2 coronavirus or other related sarbecovirus infections.

Classes IPC  ?

• C07K 16/10 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de virus de virus à ARN
• A61P 31/14 - Antiviraux pour le traitement des virus ARN
• G01N 33/569 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet pour micro-organismes, p.ex. protozoaires, bactéries, virus

Abrégé

Diagnostic biomarkers for diagnosing immune suppression/dysfunction. The diagnostic biomarkers are genes and/or transcripts that are up or down regulated compared to normal expression when a subject has been stressed either mentally and/or physically. The invention also relates to a method of detecting compromised or suppressed immune response in a subject by comparing certain diagnostic biomarkers in the subject to a control set of diagnostic biomarkers.

Classes IPC  ?

• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• C12Q 1/6809 - Méthodes de détermination ou d’identification des acides nucléiques faisant intervenir la détection différentielle
• C12Q 1/6837 - Couplage enzymatique ou biochimique d’acides nucléiques à une phase solide utilisant des réseaux de sondes ou des puces à sondes

Abrégé

A thermogenic emergency airway management device configured to prevent or treat hypothermia in a patient. The device may be configured to receive inlet air and modify one or more properties of the inlet air to output air at a temperature and/or humidity associated with the prevention and/or treatment of hypothermia. In an embodiment, the device may receive input via a user interface to determine a temperature and/or humidity associated with the air to be output to the patient. In an embodiment, the input may additionally include an amount of air to be output to the patient. In such an embodiment, the device may be configured to cause the amount of air to be output to the patient to prevent and/or treat hypothermia.

Classes IPC  ?

• A61M 16/16 - Dispositifs pour humidifier l'air à respirer
• A61M 16/10 - Préparation de gaz ou vapeurs à respirer
• A61M 15/00 - Inhalateurs

Abrégé

The present invention is directed to a continuous process for producing a foamable celluloid product by introducing a solid component (comprising nitrocellulose, chemical blowing agent (CBA), stabilizer and alcohol) and a liquid component (comprising camphor and acetone) into a mixer/devolatilizer machine where the chamber is under atmospheric pressure and having significant overhead space. The chamber is comprised of two zones wherein the first zone has a temperature that is less than the second zone and at least one rotor comprising hollow, temperature-controlled arms having a tilted angle affixed to the rotors. The rotors of the mixer/devolatilizer machine act to mix the solid and liquid components under lower shearing forces, lower mechanical stress and longer residence times than those used by twin-screw extruders.

Classes IPC  ?

• B29C 48/00 - Moulage par extrusion, c. à d. en exprimant la matière à mouler dans une matrice ou une filière qui lui donne la forme désirée; Appareils à cet effet
• B29C 48/395 - Moyens pour plastifier ou homogénéiser la matière à mouler ou pour la forcer dans la filière ou la matrice utilisant des vis entourées par un fourreau coopérant, p.ex. des extrudeuses à vis simple
• B29C 48/29 - Alimentation de l’extrudeuse en matière d’extrusion sous forme liquide
• C08J 9/00 - Mise en œuvre de substances macromoléculaires pour produire des matériaux ou objets poreux ou alvéolaires; Leur post-traitement
• B01F 27/702 - Mélangeurs à agitateurs tournant dans des récipients fixes; Pétrins avec des agitateurs tournant autour d'un axe horizontal ou incliné avec des palettes, des lames ou des bras comprenant plusieurs arbres, p.ex. dans des chambres de mélange consécutives avec des palettes s’engrenant les unes dans les autres
• B29K 1/00 - Utilisation de cellulose, de cellulose modifiée ou de dérivés de cellulose, p.ex. de viscose, comme matière de moulage

Abrégé

A series of bio-based benzoxazine monomers were developed. These benzoxazine monomers are liquid at room temperature with good processability due to their low viscosities at or near room temperature and their relatively low polymerization temperatures. Cured materials made from these bio-based benzoxazines have excellent thermal and mechanical properties.

Classes IPC  ?

• C07D 413/06 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes d'azote et d'oxygène comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une chaîne carbonée contenant uniquement des atomes de carbone aliphatiques

Abrégé

The present disclosure relates to the field of vaccines and binding molecules, as well as preparations and methods of their use in the treatment and/or prevention of disease. Described are vaccines and binding molecules, compositions containing the same, and uses thereof for treating or preventing coronavirus infections, in particular, β-coronaviruses such as SARS- CoV-2, the causative agent of COVID-19, as well as SARS-CoV-1 and other coronaviruses.

Classes IPC  ?

• A61K 39/215 - Coronaviridae, p.ex. virus de la bronchite infectieuse aviaire
• A61K 9/51 - Nanocapsules
• A61P 31/14 - Antiviraux pour le traitement des virus ARN

Abrégé

Yersinia pestis.

Classes IPC  ?

• C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p.ex. glutathion
• C12N 9/12 - Transférases (2.) transférant des groupes contenant du phosphore, p.ex. kinases (2.7)
• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p.ex. Lactobacillus, Micromonospora

Abrégé

A respirator cover or second-skin includes a support structure to cover a gas mask or respirator and is provided with cut-outs in the support structure to receive components of the respirator, the second-skin including an interior flexible gasket concentric and spaced from the outer perimeter of the second-skin which seals the cover to the outer surface of the respirator. The second skin serves to provide increased chemical protection to the user of a respirator, as an aid for garment interface, or to anchor a protective hood to the respirator.

Classes IPC  ?

• A41D 13/11 - Masques de protection du visage, p.ex. pour utilisation chirurgicale ou pour utilisation en atmosphère polluée
• A62B 18/02 - Masques
• A62B 23/02 - Filtres en vue de la protection des voies respiratoires pour appareils respiratoires

Abrégé

A polymerizable monomer prepared by reacting at least one epoxidized cardanol with (meth)acrylic anhydride or (meth)acryloyl chloride in the presence of one or more of triethylamine, tertiary amines, pyridines and pyridine derivatives; wherein the epoxidized cardanol is formed by epoxidation of an unsaturation site of a cardanol having the formula: A polymerizable monomer prepared by reacting at least one epoxidized cardanol with (meth)acrylic anhydride or (meth)acryloyl chloride in the presence of one or more of triethylamine, tertiary amines, pyridines and pyridine derivatives; wherein the epoxidized cardanol is formed by epoxidation of an unsaturation site of a cardanol having the formula: A polymerizable monomer prepared by reacting at least one epoxidized cardanol with (meth)acrylic anhydride or (meth)acryloyl chloride in the presence of one or more of triethylamine, tertiary amines, pyridines and pyridine derivatives; wherein the epoxidized cardanol is formed by epoxidation of an unsaturation site of a cardanol having the formula: wherein R is selected from hydrogen and an alkyl, or alkenyl group having 1-6 carbon atoms, and n is 7, 10, or 13, a polymer and resin made form the polymerizable monomer, and a method of preparing such a polymer. The resin created from this monomer is suitable for moderate temperature composites and coatings applications.

Classes IPC  ?

• C07C 39/19 - Composés comportant au moins un groupe hydroxyle ou O-métal lié à un atome de carbone d'un cycle aromatique à six chaînons monocycliques avec une insaturation autre que celle du cycle aromatique contenant des liaisons doubles carbone-carbone sans liaison triple carbone-carbone
• C08F 222/20 - Esters contenant de l'oxygène en plus de l'oxygène de la fonction carboxyle

Abrégé

We disclose a novel methodology for wireless networks that optimizes the transmission probability, transmit power at an agent, and the reflection matrix of an IRS for covert RF communications. Key features include: (1) An exact closed-form expression for the expected detection error probability (DEP) at an adversary is provided considering the transmission probability at the agent; and (2) a novel method to optimize the transmission probability, transmit power at the agent and the reflection matrix of the IRS with the goal of maximizing the achievable rate at a client while ensuring a covertness constraint is developed. More specifically, the method may require only one-dimensional line search schemes, achieves near-optimal performance, and exhibits enhanced achievable data rate when compared to the conventional technique without the transmission probability optimization.

Classes IPC  ?

• H04K 3/00 - Brouillage de la communication; Contre-mesures

Abrégé

Embodiments described herein relate to apparatuses, systems and methods for adjustably holding a device. For example, in one embodiment, an apparatus is provided that includes a male interlocking ring. The male interlocking ring includes a plurality of male interlocking members. The apparatus also includes a unitarily formed female interlocking plate. The unitarily formed female interlocking plate includes portions adapted to receive each of the plurality of male interlocking members. The unitarily formed female interlocking plate also includes a flexible release lever. The flexible release lever partially extends laterally in one of the portions that are adapted to receive each of the plurality of male interlocking members. Other embodiments relate to an ambidextrous holster sleeve, a holster and holster sleeve.

Classes IPC  ?

• F41C 33/04 - Accessoires spéciaux pour étuis
• F41C 33/02 - Etuis, c. à d. gaines de pistolets, p.ex. de revolvers, comportant des moyens pour les porter ou pour le porter sur soi, p.ex. à la ceinture ou sous le bras
• A45F 5/02 - Systèmes de fixation des objets aux vêtements
• A45F 5/00 - Dispositifs destinés à tenir ou porter des articles à main; Dispositifs destinés à tenir ou transporter, utilisables en voyage ou au camping

Abrégé

A material closure assembly including a material closure, such as zipper or a hook and loop fastener, having a first portion and a second portion that are configured to be releasably joined together; an electrical circuit that is configured to be closed when the first portion of the material closure is entirely joined with the second portion of the material closure; and an first indicator that is electrically connected to the electrical circuit and configured to indicate that the first portion of the material closure is entirely joined with the second portion of the material closure. The material closure assembly thus providing an active feedback system for closures on garments and personal protective equipment (PPE) to alert wearer of incomplete seals between interfaces on modular PPE which could result in the wearer of the PPE being exposed to the surrounding environment outside the PPE.

Classes IPC  ?

• A44B 19/26 - Curseurs

Abrégé

The manipulation and control of entangled particle and entangled photon properties by means of low loss interaction free quantum means is vital for studying the fundamentals of entanglement and for future applications in distributed quantum information processing, sensing and imaging. Despite its importance, achieving low loss interaction free manipulation and control of entanglement is difficult, particularly with pulsed networked systems with quantum properties changing in space and time and with intervening absorbing elements. This invention uses low loss quantum interaction free techniques and designs that can be miniaturized to efficiently and robustly send and receive quantum information and data using pulsed and continuous origin temporal and polarization entangled particles and entangled photons. The invention may be used to improve quantum communication of information and quantum networking in fiber optics, turbulent and scattering media, and free space.

Classes IPC  ?

• H04B 10/70 - Communications quantiques photoniques
• H04B 10/11 - Dispositions spécifiques à la transmission en espace libre, c. à d. dans l’air ou le vide

Abrégé

Various embodiments that pertain to artificial intelligence algorithms. A repository can retain a reusable common set of artificial intelligence algorithms. Different users can access this common set of artificial intelligence algorithms and employ individual artificial intelligence algorithms in programs as appropriately as they are developing different applications and/or products. Employment of these individual artificial intelligence algorithms can include, for example, tailoring parameters based on the desires of the individual user's desires using the same common set of algorithms or individually or as a group as appropriate.

Classes IPC  ?

• G06F 21/62 - Protection de l’accès à des données via une plate-forme, p.ex. par clés ou règles de contrôle de l’accès
• G06F 8/36 - Réutilisation de logiciel
• G06N 3/02 - Réseaux neuronaux
• G06N 5/022 - Ingénierie de la connaissance; Acquisition de la connaissance

Abrégé

Disclosed herein are methods for molecularly characterizing cervical cell samples as being negative for intraepithelial lesion or malignancy (NILM), low-grade squamous intraepithelial lesion (LSIL), or high-grade squamous intraepithelial lesion (HSIL).

Classes IPC  ?

• C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
• C12Q 1/70 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des virus ou des bactériophages
• C12Q 1/6883 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique
• C12Q 1/6851 - Amplification quantitative
• C12Q 1/686 - Réaction en chaine par polymérase [PCR]

Abrégé

The pocket detection platform (PDP) detects pathogens, toxins and chemicals of interest simultaneously by way of a multi-channeled, soft see-through plastic pouch design that consists of inner and outer compartments that promote compartmentalization and/or unidirectional sample flow. The platform enables the concurrent running of multiple detection assay techniques such as lateral flow immunoassays (LFI), Isothermal molecular assays (i.e., Recombinase Polymerase Amplification, or RPA) and/or paper-based chemical assays (i.e., M8, pH paper) from a single wet or dry sample with minimal sample processing. The PDP reduces soldier overburden by decreasing size weight, and power (SWaP) as well as training time, electronic burden, while providing a flexible, customizable assay platform that can be rapidly produced, assembled, sustained, and when contaminated, easily to dispose of.

Classes IPC  ?

• B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
• G01N 33/53 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet
• G01N 1/02 - Dispositifs pour prélever des échantillons

Abrégé

An airdrop platform is provided that includes a pallet. Under the pallet are a first outrigger main body and a second outrigger main body. The first outrigger main body and second main body each include at least one outrigger finger. When airdropped, the outrigger main bodies and outrigger fingers are configured to move from under the pallet.

Classes IPC  ?

• B64D 1/14 - Absorption des chocs à l'atterrissage
• B65D 19/00 - Palettes ou plates-formes analogues, avec ou sans parois latérales, pour supporter les charges à soulever ou à déposer
• B65D 90/00 - MANUTENTION; EMBALLAGE; EMMAGASINAGE; MANIPULATION DES MATÉRIAUX DE FORME PLATE OU FILIFORME ÉLÉMENTS D'EMBALLAGE; PAQUETS - Parties constitutives, détails ou accessoires des grands réceptacles

Abrégé

Recombinant Shigella minimal invasion plasmid constructs pRISM and pRISM-G and a method of inducing an immune response to Shigella in a subject, the method comprising administering the composition to the subject in an amount sufficient to induce an immune response to Shigella in the subject.

Classes IPC  ?

• C12N 15/74 - Vecteurs ou systèmes d'expression spécialement adaptés aux hôtes procaryotes autres que E. coli, p.ex. Lactobacillus, Micromonospora
• C12N 15/70 - Vecteurs ou systèmes d'expression spécialement adaptés à E. coli

Abrégé

A projectile delivers a pellet payload to an increased range with increased accuracy. A two piece aerodynamically stable pusher consists of a body and tailpiece. This pusher fits into a standard 40 mm cartridge case by means of three sabots. To seal against combustion gases, a three piece split rotating band is employed.

Classes IPC  ?

• F42B 14/06 - Projectiles sous-calibrés munis de sabots; Sabots pour ces projectiles
• F42B 7/08 - Bourres pour les cartouches de fusils de chasse
• F42B 10/36 - Projectiles sous forme d'aile annulaire fermée

Abrégé

A method including detecting a presence of at least one analyte in a sample from a subject wherein the at least one analyte is selected from the group consisting of: mesothelin, Galectin-3-binding protein, Clusterin, Polymeric immunoglobulin receptor, Neutrophil gelatinase-associated lipocalin, Leucine-rich alpha-2-glycoprotein, Osteopontin, Alpha-amylase 1, WAP four-disulfide core domain protein 2, Mucin-16, GSTP1, PRDX5, TXN, PRDX6, and SOD1, and determining the subject has hydrosalpinx if the sample comprises an increased level of mesothelin, Galectin-3-binding protein, Clusterin, Polymeric immunoglobulin receptor, Neutrophil gelatinase-associated lipocalin, Leucine-rich alpha-2-glycoprotein, Osteopontin, Alpha-amylase 1, WAP four-disulfide core domain protein 2, and/or Mucin-16 relative to a control, and/or a decreased level of GSTP1, PRDX5, TXN, PRDX6, and/or SOD1, relative to the control, is provided herein. The method may further include if the subject is determined to have hydrosalpinx, administering a hydrosalpinx therapy to the subject.

Classes IPC  ?

• G01N 33/68 - Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique faisant intervenir des protéines, peptides ou amino-acides

Abrégé

The disclosed subject matter relates to a superomniphobic fiber including a core having a surface and at least one channel and a plurality of nanoparticles disposed in the material core at least partially protruding from the surface of the material core.

Classes IPC  ?

• D01D 5/253 - Formation des filaments, fils ou similaires à section transversale non circulaire; Ensembles de filage à cet effet
• D01F 8/10 - Filaments, ou similaires, faits par l’homme, conjugués, c. à d. à plusieurs composants; Leur fabrication à partir de polymères synthétiques avec au moins un autre composé macromoléculaire obtenu par des réactions faisant intervenir uniquement des liaisons non saturées carbone-carbone comme constituant
• D01F 8/06 - Filaments, ou similaires, faits par l’homme, conjugués, c. à d. à plusieurs composants; Leur fabrication à partir de polymères synthétiques avec au moins une polyoléfine comme constituant
• D01D 10/02 - Traitement thermique

Abrégé

A system or a method for providing pacing guidance to an individual for a particular activity based on a physiological strain index (PSI) or an adaptive physiological strain index (aPSI). The system in at least one embodiment includes a heart rate monitor, a memory storing multiple pacing templates, a clock, an activity completion module, an output device, and a processor configured to perform multiple steps resulting in outputting pacing information to the individual. The pacing information selected in at least one embodiment is based on the individual's heart rate that provides in part a PSI or aPSI, the elapsed time for the activity, and the amount of progress through the activity.

Classes IPC  ?

• A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
• G06N 20/00 - Apprentissage automatique
• G06F 16/901 - Indexation; Structures de données à cet effet; Structures de stockage
• A61B 5/024 - Mesure du pouls ou des pulsations cardiaques
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre
• G06N 5/022 - Ingénierie de la connaissance; Acquisition de la connaissance

Abrégé

Survivability and assault multi-tool assemblies and systems that can be used in combat and tactical situations. Exemplary survivability and assault multi-tool assemblies can include a first side support, a second side support, a middle rung coupled with the first side support and the second side support, a panel coupled with the first side support and the second side support, a folding rung pivotably coupled with the first side support and the second side support, and a sliding rung slidingly received by the first side support and the second side support. Multiple survivability and assault multi-tool assemblies can be coupled together to form a survivability and assault multi-tool system.

Classes IPC  ?

• F41H 5/08 - Boucliers individuels
• E06C 1/10 - Echelles prenant appui contre des objets, p.ex. murs, poteaux, arbres à plusieurs éléments à sections s'emboîtant bout à bout
• E01D 15/12 - Ponts portatifs ou démontables par sections

Abrégé

A target stand is described that may comprise a frame; first and second rails; and a trolley. The frame may support the first and second rails. The trolley may comprise a base, a first wheel assembly coupled to the base and in contact with the first rail, and a second wheel assembly coupled to the base and in contact with the second rail, wherein the trolley is movable between respective lower ends of the first and second rails and respective upper ends of the first and second rails via the first and second wheel assemblies contacting the first and second rails. The base of the trolley may comprise a proximal portion and a cantilevered portion extending away from the proximal portion to a free end, wherein the first and second wheel assemblies are coupled to the proximal portion and the cantilevered portion extends over the first and second rails.

Classes IPC  ?

• F41J 7/00 - Cibles mobiles qui restent fixes lors du tir

Abrégé

An explosive reactive armor (ERA) enclosure for an ERA tile includes a bottom and a plurality of sidewalls extending from the bottom, where the plurality of sidewalls are continuous with each other and with the bottom so as to define an internal volume. The plurality of sidewalls are formed from a fiber-reinforced composite material having a plurality of plies of fiber sheet material. Additionally, a sidewall seam defined by abutting edges of the first ply is offset from a sidewall seam defined by abutting edges of the second ply. Methods of manufacturing ERA enclosures, including applying wrap layers and forming attachment structures for securing the fiber-reinforced composite ERA enclosure to an armor element, are also described. The composite enclosure is inexpensive and lightweight and improves the dynamic capabilities of armored vehicles using such ERA tiles.

Classes IPC  ?

• F41H 5/007 - Blindages réactifs; Blindages dynamiques
• F41H 5/013 - Montage ou fixation des plaques de blindage
• F41H 7/04 - Structure du blindage

Abrégé

The invention in at least one embodiment includes a system and method for detecting and evaluating an adaptive physiological strain index (aPSI) of an individual with a processor and in a further embodiment taking into account the fitness, age and clothing of the individual based upon physiology. The invention in at least one embodiment includes a system and method to calculate the aPSI using physiological measures. In at least one embodiment, the method obtains an individual's skin temperature and heart rate in order to calculate the individual's aPSI.

Classes IPC  ?

• A61B 5/0205 - Evaluation simultanée de l'état cardio-vasculaire et de l'état d'autres parties du corps, p.ex. de l'état cardiaque et respiratoire
• A61B 5/01 - Mesure de la température de parties du corps
• A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre
• A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus

Abrégé

The present invention relates to single thread composite fibers comprising at least one binder and at least one active catalyst for the capture and degradation of chemical threats such as chemical warfare agents (CWA), biological warfare agents, and toxic industrial chemicals (TIC) and a method for producing the same. The invention fibers are applicable to the fields of protective garments, filtration materials, and decontamination materials.

Classes IPC  ?

• B01J 35/06 - Etoffes ou filaments
• B01J 37/00 - Procédés de préparation des catalyseurs, en général; Procédés d'activation des catalyseurs, en général
• B01J 35/10 - Catalyseurs caractérisés par leur forme ou leurs propriétés physiques, en général solides caractérisés par leurs propriétés de surface ou leur porosité
• B01J 21/06 - Silicium, titane, zirconium ou hafnium; Leurs oxydes ou hydroxydes
• A62D 3/30 - Procédés pour rendre les substances chimiques nuisibles inoffensives ou moins nuisibles en effectuant un changement chimique dans les substances par réaction avec des agents chimiques
• A62D 101/02 - Substances pour la guerre chimique, p.ex. inhibiteurs de la cholinestérase

Abrégé

Components of a projectile are held together by a captive collar that is internal to the projectile. The internal captive collar is rotated about a central boss, allowing external threads on the collar to engage one of the mating components and pull that mating component into the other mating component in an axial only translation. The internal captive collar is rotated using a geared-key during assembly. This key engages a geared crown feature of the captive collar, allowing it to rotate. After assembly, the gear key is removed from the assembly. Castellated features nest within slots to transmit torque in the assembled projectile.

Classes IPC  ?

• F42B 12/20 - Projectiles ou mines caractérisés par la charge militaire, l'effet recherché ou le matériau caractérisés par la nature de la charge militaire ou par l'effet recherché du type à explosif brisant

Abrégé

An airway management isolation enclosure and a method for protecting medical personnel from infectious agents when treating a patient having an infectious disease, comprising: (a) a frame that is positioned over the head and anterior thoracic region of the patient; (b) a transparent barrier supported by frame, which covers and forms a seal around the head and anterior thoracic region of the patient and allows medical personnel to create sealable entry ports; and (c) an air flow entry and a vacuum exit connection to direct the infectious agents in the form of respiratory droplets and particles produced by the patient to flow away from the head of the patient and out of the transparent covering while the medical personnel manages the airway and upper aerodigestive tract of the patient.

Classes IPC  ?

• A61G 10/00 - Locaux de traitement à usage médical
• A61G 10/02 - Locaux de traitement à usage médical avec des moyens pour maintenir une pression déterminée, p.ex. locaux exempts de germes
• A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures

Abrégé

Various embodiments that relate to a circular disk configured to radiate a signal. The radiating disk can include edge openings. Within these edge openings power supplies can rest. When the power supplies function, they can cause the circular disk to radiate with either a dipole pattern or a cardioid pattern. A controller can manage how these power supplies function depending on if the dipole pattern or the cardioid pattern is desired.

Classes IPC  ?

• H01Q 5/40 - Structures imbriquées ou entrelacées; Dispositions combinées ou présentant un couplage électromagnétique, p.ex. comprenant plusieurs éléments rayonnants alimentés sans connexion commune
• H01Q 9/04 - Antennes résonnantes

Abrégé

Systems and methods for wireless communications comprising a plurality of agents, which together as the group, are configured to: (i) wirelessly broadcast an interference signal by forming a radiation pattern having null vectored substantially toward a client; (ii) wirelessly transmit a communication signal to the client by forming a radiation beam carrying the communication signal vectored substantially toward the client; and (iii) wirelessly broadcast a combined communication signal and interference signal to the client using phases of processes (i) and (ii). In some embodiments, the agents together as a group may be further configured to: allocate and adjust power for performing processes (i) and (ii) at substantially the same time.

Classes IPC  ?

• H04L 1/02 - Dispositions pour détecter ou empêcher les erreurs dans l'information reçue par réception à diversité
• H04B 7/06 - Systèmes de diversité; Systèmes à plusieurs antennes, c. à d. émission ou réception utilisant plusieurs antennes utilisant plusieurs antennes indépendantes espacées à la station d'émission

Abrégé

In one general embodiment, a structure includes a first diode, comprising: a first layer having a first type of dopant, and a second layer above the first layer, the second layer having a second type of dopant that is opposite to the first type of dopant. A second diode is formed directly on the first diode. The second diode comprises a first layer having a third type of dopant and a second layer above the first layer of the second diode, the second layer of the second diode having a fourth type of dopant that is opposite to the third type of dopant. In another general embodiment, a process includes a repeated sequence of growing a first layer having a first type of electrically active dopant and growing a second layer having a second type of electrically active dopant that is opposite to the first type of dopant.

Classes IPC  ?

• H01L 29/866 - Diodes Zener
• H01L 29/66 - Types de dispositifs semi-conducteurs

Abrégé

Various embodiments that relate to local communication are discussed. A radio from one geographical area can enter a communication environment of a different geographical area. However, if the radio still functions consistent with the previous geographical area, then the radio will not blend into the new geographical area. Therefore, the radio can alter operational characteristics when entering the new geographical area such that the radio blends into the new geographical area from a radio frequency perspective.

Classes IPC  ?

• H04W 4/02 - Services utilisant des informations de localisation
• H04W 8/22 - Traitement ou transfert des données du terminal, p.ex. statut ou capacités physiques
• H04W 72/04 - Affectation de ressources sans fil
• H04L 1/00 - Dispositions pour détecter ou empêcher les erreurs dans l'information reçue

Abrégé

A safe and reliable multi-component projectile enables cost effective manufacturing and assembly of the projectile. Major components of the projectile are joined by a plurality of shear pins interfacing with scalloped geometry of the components. The components are then held together by forcibly joining them using a hybrid annular-cantilevered snap fit joint. The tooth and groove arrangement exists where the teeth are at the end of a spring-leaf like feature of one of the mating parts and the groove is located on the opposite mating part.

Classes IPC  ?

• F42B 15/36 - Moyens de liaison entre le moteur-fusée et le corps d'une roquette; Raccords pour relier les différents étages d'une roquette; Moyens de désassemblage
• F42B 10/26 - Dispositions pour la stabilisation par rotation
• F42B 30/08 - Projectiles d'artillerie, p.ex. obus

Abrégé

In one embodiment, a sand boil filter apparatus has a filter cone including an inner cone mesh and an outer cone mesh, the inner cone mesh having a finer mesh than the outer cone mesh. A filter tube extends through the hollow interior of the filter cone. The filter tube includes a lower portion disposed below the open apex. The filter tube includes an upper portion disposed above the open base. The upper portion has a plurality of sets of exit openings which are spaced along a length of the upper portion to provide different possible exit heights for the plurality of sets of exit openings, each set including one or more exit openings disposed at an exit height of the filter tube. An exit height adjustment tool blocks all of the exit openings disposed below a set of unblocked exit openings selected to provide a corresponding exit height.

Classes IPC  ?

• B01D 29/085 - Entonnoirs filtrants; Leurs supports
• E02D 3/10 - Amélioration par compactage par mouillage, drainage, désaération ou emploi d'explosifs, p.ex. par mise en œuvre de drains en sable ou à mèche
• B01D 29/15 - Eléments filtrants avec des supports agencés pour la filtration à courant dirigé vers l'intérieur

Abrégé

The disclosure relates to a connector assembly including a male connector and a female connector that are connectable to each other. The male connector includes a connector main body having an annular shape and a plurality of male nubs arranged circumferentially around the connector main body, each male nub configured to be received by a corresponding female slot. The female connector includes a main body portion having an annular shape and a plurality of female slots arranged circumferentially around the main body portion, each female slot configured to receive a corresponding male nub. The male connector and female connector are configured such that when the male connector is connected to the female connector, the plurality of male nubs engages with respective ones of the plurality of female slots. The connector system is particularly applied to link building components together to form structural elements.

Classes IPC  ?

• F16B 7/04 - Assemblages par brides ou clips
• E04B 1/41 - Dispositifs d'assemblage spécialement adaptés pour être noyés dans du béton armé ou de la maçonnerie

Abrégé

Described is the preparation of novel fentanyl haptens of Formula (1) through (6) and their use in the preparation of effective fentanyl vaccines.

Classes IPC  ?

• A61K 39/385 - Haptènes ou antigènes, liés à des supports
• A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
• A61K 39/39 - Préparations médicinales contenant des antigènes ou des anticorps caractérisées par les additifs immunostimulants, p.ex. par les adjuvants chimiques
• A61P 25/36 - Médicaments pour le traitement des troubles du système nerveux des états d'abus ou de dépendance aux opiacés

Abrégé

Resins and formulations of individual monomers bearing both vinyl ester and epoxy functionality were either synthesized or formulated such that vinyl ester components capable of polymerizing by photo-induced, free radical polymerization were mixed with step-growth epoxy-amine systems, facilitating sequential cure. The vinyl ester component was photopolymerized using vat photopolymerization (VPP). Additionally, the preparation of bio-based photo curable thermosetting resins that have tailorable thermal and mechanical properties is provided. All monomers and polymers described herein are useful in a variety of applications, including additive manufacturing applications.

Classes IPC  ?

• C08F 220/18 - Esters des alcools ou des phénols monohydriques des phénols ou des alcools contenant plusieurs atomes de carbone avec l'acide acrylique ou l'acide méthacrylique

Abrégé

The chilling system provides cooling to components housed within a container by pumping propylene-glycol-water-mixture (PGWM) or equivalent through heat exchange assemblies and thermal transfer vessels. The thermal transfer vessels are filled with a paraffin-based phase change material (PCM) or equivalent solution for realizing phase change of the PCMs at selected melting points. The heat exchange assemblies are provided with thermal electric coolers for cooling the PGWM as it travels through the heat exchangers. The cooled PGWM is directed into and through a target cooling manifold of a target heat exchanger assembly to realize cooling the housed components. The system operates on direct current at under 500 watts of power and requires no Freon-type refrigerants or compressors. A microcontroller controls switches for realizing desired flow paths of the PGWM upon receiving phase change and temperature information from sensors.

Classes IPC  ?

• F25B 21/04 - Machines, installations ou systèmes utilisant des effets électriques ou magnétiques utilisant l'effet Nernst-Ettinghausen réversibles

Abrégé

A blast attenuator for blast overpressure has features that allow for blast attenuation and ease of projectile loading from the muzzle of the weapon system. This combination of physical ease of use and blast reduction allows the system to achieve high levels of performance without making significant concessions to operator safety.

Classes IPC  ?

• F41A 21/32 - Accessoires de bouches de canon ou freins de bouche
• F41A 21/30 - Silencieux
• F41C 9/08 - Armes à feu individuelles à chargement par la bouche; Armes à feu individuelles comportant un mécanisme d'allumage à silex; Accessoires pour ces armes

Abrégé

Antiviral drugs targeting the N-terminal domain (NTD) of the spike receptor binding domain (RBD) and methods of treating a subject suffering from coronavirus.

Classes IPC  ?

• A61P 31/02 - Antiseptiques locaux
• A61K 31/4184 - 1,3-Diazoles condensés avec des carbocycles, p.ex. benzimidazoles
• A61K 31/445 - Pipéridines non condensées, p.ex. pipérocaïne
• A61K 31/551 - Composés hétérocycliques ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines ayant des cycles à sept chaînons, p.ex. azélastine, pentylènetétrazole ayant deux atomes d'azote comme hétéro-atomes d'un cycle, p.ex. clozapine, dilazèpe
• A61K 31/4468 - Pipéridines non condensées, p.ex. pipérocaïne ayant un atome d'azote lié directement en position 4, p.ex. clébopride, fentanyl
• C07D 295/112 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de car avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes d'oxygène ou de soufre liés par des liaisons doubles avec les atomes d'azote du cycle et les atomes d'oxygène ou de soufre liés par des liaisons doubles séparés par des carbocycles ou par des chaînes carbonées interrompues par des carbocycles
• C07D 295/096 - Composés hétérocycliques contenant des cycles polyméthylène imine d'au moins cinq chaînons, des cycles aza-3 bicyclo [3.2.2] nonane, piperazine, morpholine ou thiomorpholine, ne comportant que des atomes d'hydrogène liés directement aux atomes de car avec des radicaux hydrocarbonés substitués liés aux atomes d'azote du cycle substitués par des atomes d'oxygène ou de soufre liés par des liaisons simples avec les atomes d'azote du cycle et les atomes d'oxygène ou de soufre séparés par des carbocycles ou par des chaînes carbonées interrompues par des carbocycles
• C07D 409/04 - Composés hétérocycliques contenant plusieurs hétérocycles, au moins un cycle comportant des atomes de soufre comme uniques hétéro-atomes du cycle contenant deux hétérocycles liés par une liaison directe de chaînon cyclique à chaînon cyclique
• C07D 223/04 - Composés hétérocycliques contenant des cycles à sept chaînons ne comportant qu'un atome d'azote comme unique hétéro-atome du cycle non condensés avec d'autres cycles  avec uniquement des atomes d'hydrogène, des atomes d'halogènes, des radicaux hydrocarbonés ou hydrocarbonés substitués, liés directement aux atomes de carbone du cycle

Abrégé

An airborne delivery system employs unmanned aerial vehicles (UAVs) released from an airborne platform, such as a Joint Precision Airdrop System (JPAD), to more accurately deliver supplies. The airborne delivery system is configured to be mounted on a JPAD, or similar airborne platform. As with a conventional JPAD, the JPAD is then released from an airborne vehicle. After a certain amount of flight time, one or more UAVs are released mid-flight from the airborne delivery system.

Classes IPC  ?

• B64D 1/12 - Largage
• B64C 39/02 - Aéronefs non prévus ailleurs caractérisés par un emploi spécial

Abrégé

An apparatus for mounting and securing medical/surgical devices may be attached to a litter (40), The medical/surgical devices may include. for example, IV holders (186), aspirators (144). cardiac monitors (148) , defibrillators (150) , infusion pumps 152 (152), ventilators (146) and other devices. The apparatus frame assembly (10) includes rails (12), (14), (16), (18), (20), (46), (48), (50), (52) having cross-sections of standard surgical rails, for attachment of slidable rail clamps (84), (104). Medical device mounts (108), (110), (112) are attached to the slidable rail clamps. The medical device mounts have height and/or rotational adjustment to improve patient access and view. The apparatus may be mounted longitudinally anywhere along the litter to maximize access to the patient.

Classes IPC  ?

• A61G 13/10 - Tables d'opération; Leurs accessoires - Parties constitutives, détails ou accessoires

Abrégé

Inhibitors against SARS-COV-1, SARS-CoV-2 (Covid-19), MERS-CoV, and variants within each, including methods of treating a subject suffering from such respiratory disease.

Classes IPC  ?

• A61K 31/517 - Pyrimidines; Pyrimidines hydrogénées, p.ex. triméthoprime condensées en ortho ou en péri avec des systèmes carbocycliques, p.ex. quinazoline, périmidine
• A61P 31/14 - Antiviraux pour le traitement des virus ARN
• A61K 31/427 - Thiazoles non condensés et contenant d'autres hétérocycles

Abrégé

3, such that 0≤x≤1, for detecting, sensing, filtering, reacting, or absorbing toxic chemicals, such as chemical warfare agents (“CWAs”) and their structural analogs, toxic industrial chemicals and narcotics, wherein the dielectric material is incorporated into a sensor for detecting, sensing, filtering, reacting, or absorbing the toxic chemicals.

Classes IPC  ?

• G01N 33/00 - Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes
• C01G 23/00 - Composés du titane
• C01G 25/02 - Oxydes

Abrégé

A dual-use spring attached to a small satellite that performs two common functions for small satellites including operating as a communications antenna for the small satellite, which eliminates the need for a separate antenna deployment step, and ejecting the small satellite from a modified deployment container mounted on a launch vehicle. The deployment container is modified by removing a conventional deployment spring and pusher plate, which increases available container space.

Classes IPC  ?

• B64G 1/10 - Satellites artificiels; Systèmes de tels satellites; Véhicules interplanétaires
• B64G 1/64 - Systèmes pour réunir ou séparer des véhicules spatiaux ou des parties de ceux-ci, p.ex. aménagement pour l'accostage ou l'amarrage
• H01Q 1/08 - Moyens pour replier tout ou partie des antennes
• H01Q 1/28 - Adaptation pour l'utilisation dans ou sur les avions, les missiles, les satellites ou les ballons
• H01Q 1/36 - Forme structurale pour éléments rayonnants, p.ex. cône, spirale, parapluie

Abrégé

Various embodiments relate to network capabilities. Devices of a network can have different capabilities. The network can provide artificial intelligence (AI) enabled, machine learning (ML) enabled, deep learning (DL) enabled networked access to these capabilities. The capabilities can share a common AI/ML/DL-enabled open layer-based net-centric logical protocol architecture. Also, different features can be achieved through different layers. As an example, AI enabled access can be achieved through the application layer, ML enabled access and DL enabled access can be achieved through the presentation layer and the session layer, and network access is achieved through the transport layer, the network layer, the link layer, and the physical layer.

Classes IPC  ?

• G06N 20/00 - Apprentissage automatique
• G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
• G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales

Abrégé

The disclosure relates to compositions, assays, methods and kits comprising one or more amino acid sequences of a filovirus protein, or a fragment thereof, which find use in the detection of a filovirus infection and/or the presence of antibodies specific for a filovirus in a biological sample.

Classes IPC  ?

• C07K 14/005 - Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés provenant de virus

Abrégé

The present invention is directed to preparing pyrophoric foam granules having a specific infrared signature comprising the steps of (a) mixing a composition comprising a metal salt, carbohydrate, and wetting agent into a homogenous paste, (b) extruding the composition into strands, (c) cutting or spheronizing the strands into a predetermined size or length based on a specific thermal or infrared response to produce pyrophoric foam granules and (d) activating the granules by heating the composition at elevated temperatures under an inert or reducing atmosphere until the matrix is carbonized and the metal salt is reduced.

Classes IPC  ?

• C06B 21/00 - Appareils ou méthodes pour la mise en œuvre des explosifs, p.ex. mise en forme, coupage, séchage

Abrégé

The presently disclosure relates to a system and method for bioelectronic communications. In certain embodiments the system comprises a bacterial cell or cells that comprise a genetic system for high-efficiency over-expression and secretion of recombinant proteins in bacteria. In certain embodiments, the system and method operate in a “pump-then-burst release” fashion to rapidly achieve high yields extracellularly. In certain embodiments, the system and method include quorum sensing-derived regulation, which may enable auto-induction of a protein's expression and secretion.

Classes IPC  ?

• C12P 21/02 - Préparation de peptides ou de protéines comportant une séquence connue de plusieurs amino-acides, p.ex. glutathion
• C12N 5/10 - Cellules modifiées par l'introduction de matériel génétique étranger, p.ex. cellules transformées par des virus
• A61K 38/19 - Cytokines; Lymphokines; Interférons
• C12N 1/20 - Bactéries; Leurs milieux de culture

Abrégé

A projectile with a payload protection mechanism protects, prior to and during firing, a fragile payload, where the payload must be positioned forward in the nose of the projectile, within a frangible ogive which provides little protection to rough handling, at time of downrange function. The payload protection mechanism allows the payload to move axially within the projectile, and initially slid rearward in the more robust metal body of the projectile. The payload is retained within the body by a locking and release mechanism, until the launching of the projectile triggers (by environmental forces such as setback or spin) the release of a locking and release mechanism. Unlocking the mechanism allows the payload to slide forward within the projectile into the ogive so the payload can function as required.

Classes IPC  ?

• F42B 12/62 - Munitions en grappes ou munitions-cargo, c. à d. projectiles portant un seul ou plusieurs sous-projectiles les sous-projectiles étant éjectés dans une direction parallèle à l'axe longitudinal du projectile porteur

Abrégé

Various embodiments are described that relate an electrical current connector. The electrical current connector can be configured to provide electrical current when pressure is applied to a prong set. This pressure can cause a contact to engage with a connector. This can complete a circuit that allows the electrical current to flow. The connector can be coupled to a cable that can be configured to transfer data along with the electrical current. The cable can have an inner portion that transfers the data while an outer portion that surrounds the inner portion transfers the current.

Classes IPC  ?

• G01R 31/50 - Test d’appareils, de lignes, de câbles ou de composants électriques pour y déceler la présence de courts-circuits, de continuité, de fuites de courant ou de connexions incorrectes de lignes
• H01R 13/193 - Moyens pour améliorer la pression de contact à la fin de l'engagement des pièces de couplage
• H01R 13/703 - Association structurelle avec des composants électriques incorporés avec interrupteur incorporé actionné par l'engagement ou le retrait des pièces de couplage

Abrégé

Disclosed herein are embodiments of an energetic compound and methods of making and using the same. Energetic compound embodiments disclosed herein exhibit physical and chemical properties that facilitate their use in various applications, such as high energy propellant plasticizers, melt-castable explosives, and the like. Efficient and safe method embodiments for making the disclosed energetic compound embodiments are described herein.

Classes IPC  ?

• C07D 271/06 - Oxadiazoles-1, 2, 4; Oxadiazoles-1, 2, 4 hydrogénés
• C06B 25/34 - Compositions contenant un composé organique nitré le composé étant une amine nitrée acyclique, cyclanique ou hétérocyclique

Abrégé

Novel electrically-isolated high-voltage sensors are provided which have low power dissipation. The sensors are formed of a circuit comprising first and second portions separated by an electrical isolation boundary with the first portion used for high-voltage, and the second portion for low-voltage. While they are decoupled electrically, they are coupled both optically and magnetically. The first portion comprises an LED which generates an optical signal corresponding to a high-voltage signal across the electrical-isolation boundary. The second portion comprises a photodiode which receives the optical signal emitted from the LED and outputs a corresponding low-voltage electrical signal. A temperature-compensating LED biasing sub-circuit may span both portions and include a temperature sensor, a coupled inductor magnetically coupling the electrical isolation boundary, and a rectifier and filter, to provide a bias to the LED which biases the LED to operate in a substantially-linear manner irrespective of the ambient temperature.

Classes IPC  ?

• G01R 15/22 - Adaptations fournissant une isolation en tension ou en courant, p.ex. adaptations pour les réseaux à haute tension ou à courant fort utilisant des dispositifs émetteurs de lumière, p.ex. LED, optocoupleurs
• G01R 19/32 - Compensation des variations de température
• H05B 45/18 - Commande de l'intensité de la lumière à l'aide d'un retour de température

Abrégé

The present disclosure describes methods and systems for predicting if a subject has an increased risk of having or developing venous thromboembolism, including prior to the detection of symptoms thereof and/or prior to onset of any detectable symptoms thereof. The present disclosure also describes a method of generating a model for predicting venous thromboembolism.

Classes IPC  ?

• G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
• G16B 40/00 - TIC spécialement adaptées aux biostatistiques; TIC spécialement adaptées à l’apprentissage automatique ou à l’exploration de données liées à la bio-informatique, p.ex. extraction de connaissances ou détection de motifs

Abrégé

An acoustic metamaterial structure acts as a sound reducing filter in that the level of sound that exits the structure is much less than the magnitude of sound that enters the structure. In forming the structure, modular stages of a given geometry are stacked upon one another to create a cell. Each stage of the cell is provided with a nozzle that is acoustically connected to the nozzles of other stages of the cell. The stages have chambers that are positioned radially or laterally outside of the respective nozzles, with the chambers of the cell being acoustically connected to one another. An amalgamation of cells are arranged in an adjacent formation, with chambers of the cells being acoustically connected to one another for purposes of protecting items, components and people from destructive levels of sound. The geometry of the nozzles and chambers are designed for economical additive manufacture with acoustic infills.

Classes IPC  ?

• G10K 11/162 - Sélection de matériaux

Abrégé

An acoustic-metamaterial acts as a sound reducing filter in that the level of sound that exits the structure is much less than the magnitude of sound that enters the structure. In forming the structure, modular stages of a given geometry are stacked upon one another to create a cell. Each stage of the cell is provided with a nozzle that is acoustically connected to the nozzles of other stages of the cell. The stages have chambers that are positioned radially or laterally outside of the respective nozzles, with the chambers of the cell being acoustically connected to one another. An amalgamation of cells are arranged in an adjacent formation, with chambers of the cells being acoustically connected to one another for purposes of protecting items, components and people from destructive levels of sound.

Classes IPC  ?

• G10K 11/162 - Sélection de matériaux

Abrégé

Anti-CCHFV antibodies with neutralizing potency and protective efficacy against CCHFV are provided, as well as methods for their identification, isolation, generation, and methods for their preparation and use are provided.

Classes IPC  ?

• A61K 39/42 - Anticorps; Immunoglobulines; Immunsérum, p.ex. sérum antilymphocitaire viraux
• A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p.ex. composés antiphlogistiques et pour le cœur 
• A61P 31/14 - Antiviraux pour le traitement des virus ARN
• C07K 16/10 - Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de virus de virus à ARN

Abrégé

The present invention is directed to a process for preparing light curable energetic polymeric binders. The process for preparing such binder comprises the steps of mixing a pre-polymer such as PGN or GAP having a terminal hydroxyl group with a solvent and adding reactants wherein the reactant has a light curable moiety and a pre-polymer reactive moiety. Catalysts such as carbodiimide and DMAP may be further added to the mixture.

Classes IPC  ?

• C08G 65/332 - Polymères modifiés par post-traitement chimique avec des composés organiques contenant de l'oxygène contenant des groupes carboxyle, ou leurs halogénures ou esters
• C08G 65/22 - Ethers cycliques possédant en dehors du cycle au moins un atome autre que le carbone et l'hydrogène
• C06B 45/10 - Compositions ou produits définis par une structure ou des dispositions particulières des composants ou du produit comportant des particules solides dispersées dans une solution solide ou une matrice le composé étant une solution solide ou matrice contenant un composant organique le composant organique contenant une résine
• C08G 65/333 - Polymères modifiés par post-traitement chimique avec des composés organiques contenant de l'azote
• C08G 18/10 - Procédés mettant en œuvre un prépolymère impliquant la réaction d'isocyanates ou d'isothiocyanates avec des composés contenant des hydrogènes actifs, dans une première étape réactionnelle
• C08G 18/50 - Polyéthers contenant des hétéro-atomes autres que l'oxygène

Abrégé

A projectile enables axial assembly and precise angular alignment of cylindrical or ogival sections of the projectile without interfering with internal parts spanning those sections. The projectile includes a turnbuckle design that minimizes Outer Mold Line (OML) transitions and maintains structural integrity. Advantageously, the turnbuckle allows surface mounted antennas and internal electronics to span structural sections of the projectile. The minimal OML produces less turbulence and drag. Finally, the turnbuckle is structurally robust for gun launched applications.

Classes IPC  ?

• F42B 10/46 - Coiffes aérodynamiques; Pare-brise; Radômes
• F42B 33/00 - Fabrication de munitions; Démontage de munitions; Appareils à cet effet

Abrégé

A laser ignition assembly comprises first and second mounting surfaces opposed to each other. A central cavity is formed through the surfaces and sized to receive energetic material therein. A vertical solder bridge is formed between the surfaces and an edge emitting laser diode disposed between the surfaces. The laser diode is oriented such that a light fluence therefrom is directed in a radial direction into the central cavity. The surfaces can be circuit boards, e.g., copper clad, rigid circuit boards, and have an annular shape. The central cavity can be further defined by an interboard gap between the surfaces. The ignition assembly can fit within a primer cup of a munition.

Classes IPC  ?

• F42C 19/12 - Amorces; Détonateurs électriques
• H01S 5/0233 - Configuration de montage des puces laser

Abrégé

Disclosed is a laser system including a first laser and a second laser. The first laser includes a laser cavity, and a gas phase molecular gain medium disposed in the laser cavity, the gain medium having an absorption band. The second laser is a solid state laser configured to be continuously tunable, with respect to an emission wavelength of the second laser, over the absorption band of the gain medium, and the second laser is tuned to pump rotational vibrational transitions in the gain medium to achieve a rotational population inversion.

Classes IPC  ?

• H01S 3/131 - Stabilisation de paramètres de sortie de laser, p.ex. fréquence ou amplitude par commande du milieu actif, p.ex. par commande des procédés ou des appareils pour l'excitation
• H01S 3/0941 - Procédés ou appareils pour l'excitation, p.ex. pompage utilisant le pompage optique par de la lumière cohérente produite par un laser à semi-conducteur, p.ex. par une diode laser