Systems and methods for rendering a model of the face of a user in real-time. A machine learning trained model (901) is used to generate skin parameters for a BSSRDF function from real or synthetic image data, depth data, albedo data, and IR data. Hair growth and degeneration is estimated using additional machine learned models (401, 501) from a sequence of images. The systems and methods provide a model or synthetic representation in real-time of a user that includes accurate skin rendering and estimated hair rendering that can track evolution of hair loss and regrowth.
Health information is integrated (106) into a framework system (400). PGHD and clinical data are integrated (106) into a patient data model (240). The PGHD data as integrated may be compressed or otherwise processed (104) to reduce the volume and/or frequency of the data for greater ease in understanding the PGHD data. A user interface (220) for this data model (240) allows for access to both types of data (PGHD and clinical data) by a patient or a physician. Artificial intelligence may be used to further consolidate the data by providing one or more biomarkers (120) estimated from both types of data, allowing for patient and/or physician goal, treatment success, and/or adverse event monitoring.
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
3.
ARRAY OF LIGHT SOURCES, FOURIER PTYCHOGRAPHIC IMAGING SYSTEM AND METHOD OF PERFORMING FOURIER PTYCHOGRAPHY
The present disclosure relates to an array of light sources (2) for a Fourier ptychographic imaging system (100), including at least two adjacent light sources (2) which preferably differ from each other in a property of light beams emitted from them and are configured to illuminate a sample (4) at different angles of incidence for reconstructing a single image of the sample using Fourier ptychography, wherein the property of light beams of each light source (2) is configured to match the sample (4) for increasing a contrast and/or a color or material information content in the reconstructed single image of the sample (4). In embodiments, one or more light sources is a UV light source. In embodiments, the sample is a biological sample. In embodiments, the FPM includes UV transparent components and/or materials such as quartz.
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
4.
SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH CAN UTILIZE AND/OR PROVIDE SIMULTANEOUS MULTI-SLICE PROTOCOL AND DEEP-LEARNING MAGNETIC RESONANCE IMAGING RECONSTRUCTION
Various exemplary techniques, methods, computer-accessible medium and systems for reconstructing one or more magnetic resonance images ("MRI") for multiple slices based on an MRI measurement dataset that is acquired using a simultaneous multi-slice protocol and undersampling and K-space can be provided. A convolutional neural network can be used to implement a regularization operation of an iterative optimization for the reconstruction, e.g., an unrolled neural network or variational neural network. A combination with Dixon imaging, e.g., separation of multiple chemical species, can be utilized.
G01R 33/44 - Dispositions ou appareils pour la mesure des grandeurs magnétiques faisant intervenir la résonance magnétique utilisant la résonance magnétique nucléaire [RMN]
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique
G01R 33/565 - Correction de distorsions d'image, p.ex. dues à des inhomogénéités de champ magnétique
The invention relates to a ptychographic imaging system (100), comprising at least one light source (2), a converging lens (6) and a rotatable mirror (4) configured to be placed at a 2f plane of the converging lens (6) and reflect light beams emitted from the light source (2) to the converging lens (6).
G02B 21/36 - Microscopes aménagés pour la photographie ou la projection
G02B 7/182 - Montures, moyens de réglage ou raccords étanches à la lumière pour éléments optiques pour miroirs pour miroirs
G02B 26/08 - Dispositifs ou dispositions optiques pour la commande de la lumière utilisant des éléments optiques mobiles ou déformables pour commander la direction de la lumière
Embodiments of the present invention disclose a method and apparatus for positioning a movable component in X-ray imaging. The method comprises: acquiring a 3D image that is captured using a camera component and characterizes a motion process of a movable component; acquiring motion information of the movable component, detected by a motion sensor; positioning the movable component based on the 3D image and the motion information. The embodiments of the present invention combine the 3D image of the movable component with motion information of the movable component to position the movable component, so can increase the precision of positioning of the movable component, and in particular can improve image stitching quality and the precision of positioning of a detector, as well as being able to reduce the overlap requirements in image stitching and lower the exposure dose.
The invention relates to a method for alternately displaying graphical representations, comprising: a) providing a first image which comprises a presentation of an anatomical structure of an object of interest, b) providing a second image which reproduces a spatial and/or time-related change in the object of interest, c) displaying a graphical representation of the first or second image on a display surface of a display unit, and d) displaying a graphical representation of the respective other image on the display surface of the display unit, steps c) and d) being carried out one after the other and steps b) to d) being carried out repeatedly. The invention also relates to a system and to a computer program product.
Remote emergency care system (1) for video conferencing between an emergency site (8) and a remote first communication device (2) of a physician, wherein the first communication device (2) comprises first videoconference equipment (17), the remote emergency care system (1) comprising: - a second communication device (4) mounted to an mobile medical care center, wherein the second communication device (4) is adapted to communicate with the first communication device (2) via at least one first communication link (10, 10a, 10b, 10c, 10d) using at least one public mobile network (9, 9a, 9b, 9c, 9d), - a mobile point of care terminal (7) as a third communication device (3) for medically trained staff, wherein the second and the third communication device (4, 3) communicate via a private, local second communication link (11) and wherein the third communication device (3) comprises second videoconference equipment (18), and - a control device for establishing a video conference between the first and the third communication device (2, 3) using the first and second communication links (10, 10a, 10b, 10x, 10d, 11), wherein the second communication link (11) is a private mobile communication link in a private mobile network (12) established by the second communication device (4), in particular a private LTE network.
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
G16H 80/00 - TIC spécialement adaptées pour faciliter la communication entre les professionnels de la santé ou les patients, p.ex. pour le diagnostic collaboratif, la thérapie collaborative ou la surveillance collaborative de l’état de santé
H04W 84/04 - Réseaux à grande échelle; Réseaux fortement hiérarchisés
H04W 12/03 - Protection de la confidentialité, p.ex. par chiffrement
H04W 4/90 - Services pour gérer les situations d’urgence ou dangereuses, p.ex. systèmes d’alerte aux séismes et aux tsunamis
H04W 12/088 - Sécurité d'accès utilisant des filtres ou des pare-feu
H04W 12/121 - Système de détection d’intrusions sans fil [WIDS]; Système de prévention d’intrusions sans fil [WIPS]
9.
METAL-FILLED RESIN FORMULATION, 3D PRINTING METHOD, AND ADDITIVELY MANUFACTURED COMPONENT
The present invention relates to a metal-filled resin formulation, more particularly for a 3D printing method, on the basis of layer-by-layer photopolymerization for the manufacture of a component, wherein the resin formulation contains a photopolymerizable matrix component, a dense metal filler having a specific minimum volume fraction, and a photoinitiator. A component is additively manufactured by the layer-by-layer selective curing of the metal-filled resin formulation by means of irradiation with light. The invention in particular relates to the high-precision manufacture of radiation-absorbing components on the basis of lithographic additive processes such as SLA; because of the special choice of the formulation used, wall thicknesses down to less than 100 μm are possible while still achieving good radiation hardness and good surface quality.
B29C 64/124 - Procédés de fabrication additive n’utilisant que des matériaux liquides ou visqueux, p.ex. dépôt d’un cordon continu de matériau visqueux utilisant des couches de liquide à solidification sélective
The invention relates to a mammography system (1) having: a) a stand unit (2) for positioning the mammography system on the floor; b) an L-shaped source unit (3), one leg (4) of which is rotatably mounted on a front side of the stand unit and connected to the x-ray detector (20), and the other leg (5) projects substantially perpendicular, so that an x-ray source (6) is arranged at the end of the source unit that is remote from the stand unit; c) a substantially U-shaped protective unit (7), the first leg (9) of which is attached, in particular on a rear side, to the stand unit, mounted such that it can rotate in particular independently of the source unit, the second leg (10) extends along the upper side of the source unit in a first operating state, and the third leg (11) has a protective shield (8) for supporting the patient's head, at the end of the protective unit remote from the stand element.
The invention relates to a local coil (26), having a mounting (35), at least one antenna (32), and a flexible element. The mounting (35) is designed to position the local coil (26) in a specified position relative to the head (43) of a patient (15), wherein the at least one antenna (32) is designed to receive high-frequency signals in a frequency and power range of a magnetic resonance measurement, and the flexible element is designed to at least partly form the local coil (26) on the surface contour of the head (43) of the patient (15). The local coil (26) at least partly surrounds the head (43) of the patient (15) when the local coil is positioned during use, and a section of the local coil (26), comprising the at least one antenna (32), can be positioned on the temporomandibular joint (42) of the patient (15) by means of the mounting (35). The local coil (26) is designed to receive magnetic resonance signals of the temporomandibular joint (42) of the patient (15) by means of the at least one antenna (32). The invention additionally relates to a magnetic resonance device (10) comprising a local coil (26), said magnetic resonance device (10) being designed to detect magnetic resonance signals of a diagnostically relevant region of the head (43) of the patient (15) using the local coil (26).
The invention relates to a local coil (26), comprising at least one antenna (32), a base element (30), a holding element, a first guide mechanism (33), a second guide mechanism (33) and a safety mechanism (50), wherein the at least one antenna (32) is designed to receive high-frequency signals in a frequency range and power range of a magnetic resonance measurement and wherein the at least one antenna (32) is mechanically connected to the holding element (31), wherein the base element (30) is designed to hold the holding element (31) together with the at least one antenna (32) in a position appropriate for use on a diagnostically relevant body region of a patient (15), wherein the first guide mechanism (33) is mechanically connected to the base element (30) and the holding element (31) and is designed to position the holding element (31) variably relative to the base element (30) and wherein the second guide mechanism (33) is mechanically connected to the holding element (31) and the at least one antenna (32) and is designed to position the at least one antenna (32) variably relative to the holding element (31), wherein the safety mechanism (50) is designed to prevent a collision between the at least one antenna (32) and the patient (15), in particular the diagnostically relevant body region of the patient (15), during a transfer of the holding element (31) from an open position into a closed position by means of the first guide mechanism (33). The invention further relates to a magnetic resonance apparatus (10) comprising a local coil (26) according to the invention.
G01R 33/34 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails de structure, p.ex. résonateurs
G01R 33/3415 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails de structure, p.ex. résonateurs comprenant des bobines de surface comprenant des ensembles de bobines
13.
DENTAL COIL AND MAGNETIC RESONANCE DEVICE FOR IMAGING A JAW REGION
The invention relates to a dental coil (26) comprising a first element (30) and a second element (32). The first element (30) consists of a dimensionally stable material and has a recess (31) which is suitable for receiving a mouth region and/or a nose region of a patient (15) when the dental coil (26) is positioned on the jaw region (43) of the patient (15) during use, and the second element (32) has a flexible element which is designed to allow the flexible element to take the shape of the jaw region (43) of the patient (15), wherein the first element (30) and the second element (32) have an antenna which is designed to receive high-frequency signals in a frequency and power range of a magnetic resonance measurement. The invention additionally relates to a magnetic resonance device (10) comprising a dental coil (26), said magnetic resonance device (10) being designed to image the jaw region (43) of a patient (15).
G01R 33/34 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails de structure, p.ex. résonateurs
G01R 33/3415 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails de structure, p.ex. résonateurs comprenant des bobines de surface comprenant des ensembles de bobines
14.
METHOD FOR SECURELY STORING AND RETRIEVING MEDICAL DATA
A method for securely storing (and/or securely retrieving) medical data, MD, the method for storing comprising at least steps of: - obtaining, in a secure environment, medical data which include patient property data as well as patient identifier data wherein the patient identifier data indicate at least one patient to which the patient property data correspond; - generating, in the secure environment de-identified medical data by replacing the patient identifier data in the medical data, MD, with non-patient-identifying coded identifiers, NPICI; - generating, in the secure environment, a re-identifying database indicating correspondences between the non-patient-identifying coded identifiers, NPICI and the PID; - generating an encrypted re-identifying database by applying, in the secure environment, at least one symmetric and/or asymmetric encryption method to the re-identifying database, RIDB; - storing the encrypted re-identifying database and the de-identified medical data on a cloud storage outside of the secure environment.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
G06F 21/62 - Protection de l’accès à des données via une plate-forme, p.ex. par clés ou règles de contrôle de l’accès
15.
DEVICE AND METHOD FOR OBSERVING A BIOLOGICAL PROBE
The invention relates to a device for observing a biological probe. The device comprises an optical microscope, a beam splitting device and a plurality of cameras. The optical microscope comprises a support structure for supporting the biological probe in a beam path of the optical microscope. The beam splitting device is arranged in the beam path downstream from the biological probe, wherein the beam splitting device is configured to split the beam path into a plurality of beam paths. Each camera is arranged in one beam path of the plurality of beam paths and is configured to generate camera images of the biological probe. For at least some of the cameras, focal lengths of the cameras differ from one another and/or wavelength ranges captured by the cameras for generating the camera images of the biological probe differ from one another and/or sensor types of the cameras ( 41a-4na; 41b-44b) differ from one another.
Methods and systems for generating display data of a medical image data set are provided. Methods and systems are directed to identify, for a target medical image series of a patient at a first point in time, a reference medical image series of the patient taken at a second point in time different from the first point in time. In particular, the selection may be based on a comparison of respectively depicted body regions of the patient. Further, methods and systems may be directed to generate display data to cause a display device to display a rendering of the reference medical image series based on a registration between the target medical image series and the reference medical image series.
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p.ex. DICOM, HL7 ou PACS
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
G06F 16/58 - Recherche caractérisée par l’utilisation de métadonnées, p.ex. de métadonnées ne provenant pas du contenu ou de métadonnées générées manuellement
The invention relates to a display device for displaying an augmented reality, wherein the display device comprises a detection unit and a display unit. The display unit is configured to be at least partially transparent, the detection unit is configured to detect real objects in a visual field of the display device, the display unit is configured to display a graphic representation of the augmented reality and the augmented reality comprises at least one virtual object. The display device is configured: - to arrange the at least one virtual object depending on the real objects detected in the augmented reality and - to adjust a blur of the at least one virtual object depending on its virtual arrangement. The invention further relates to a method for providing an augmented reality and to a computer program product.
A method (200), and a device (100) for determining onset of sepsis is provided. In one aspect, the method (200) includes receiving at least one medical dataset associated with the patient, wherein the medical dataset comprises a plurality of features. Further, the method (200) includes extracting one or more features from the medical dataset, wherein the one or more features comprises parameters associated with the patient which are indicators of sepsis. Additionally, the method (200) includes imputing at least one missing value in the medical dataset, wherein the missing value is associated with the features in the medical dataset. The method (200) also includes determining an output parameter indicative of the onset of sepsis in the patient by using the one or more features and the at least one missing value in the medical dataset as an input for one or more trained machine learning model (700). Furthermore, the method (200) includes generating an alert (ALT) indicating the onset of sepsis in the patient if the output parameter fulfills a pre-defined criterion associated with sepsis.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G16H 50/30 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour l’évaluation des risques pour la santé d’une personne
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
G16H 10/40 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données relatives aux analyses de laboratoire, p.ex. pour des analyses d’échantillon de patient
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
The present disclosure provides an X-ray generating apparatus and an imaging device, wherein the X-ray generating apparatus comprises: a casing; a heat-conducting member, the heat- conducting member being arranged to run through the casing, and a through-channel being provided in the interior of the heat-conducting member, the through-channel being configured to circulate a cooling medium; an anode target, the anode target being configured to receive electron bombardment in order to generate X-rays, and the anode target being arranged in the casing and surrounding the heat-conducting member in a rotatable fashion. The present disclosure also provides an imaging device, comprising a cooling system and an X-ray gen- erating apparatus; the cooling system is in communication with two ends of the heat-conducting member, and the cooling system is configured to convey a cooling medium into the heat-conducting member. In the X-ray generating apparatus and imaging device provided in the present disclosure, the cool- ing medium can carry away heat from the anode target through the through-channel, thus the heat dissipation efficiency and service life of the X-ray generating apparatus are increased.
The invention relates to a dental coil (26) comprising a transmitter unit with at least one antenna (37), a receiver unit with an array of antennas (32), and a carrier element (30) which is designed to be positioned in use on the jaw region (43) of the patient (15) and to follow at least part of the outer shape of the jaw region (43) of the patient (15), wherein the carrier element (30) is moreover designed to hold the array of antennas (32) of the receiver unit in a predetermined relative position with respect to the jaw region (43) of the patient (15), such that the array of antennas (32) of the receiver unit borders the outer shape of the jaw region (43) in the predetermined relative position. The invention further relates to a magnetic resonance system (1) having a magnetic resonance apparatus (10) and a dental coil (26), wherein the magnetic resonance apparatus (10) is designed to detect magnetic resonance signals from a jaw region (43) of the patient (15) by means of the dental coil (26).
G01R 33/34 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails de structure, p.ex. résonateurs
G01R 33/3415 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails de structure, p.ex. résonateurs comprenant des bobines de surface comprenant des ensembles de bobines
G01R 33/36 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails électriques, p.ex. adaptations ou couplage de la bobine au récepteur
21.
SYSTEM AND METHOD FOR DETERMINING THE POSITIONING OF A PATIENT
The invention relates to a system (20) for determining the positioning of a body area (O) of a patient in a magnetic resonance imaging scanner (2), the system comprising a sensor assembly (21) and a data transfer device (22), wherein the data transfer device (22) is designed to transfer the sensor data (SD) of the sensor assembly (21) out of the magnetic resonance imaging scanner (2), and wherein the sensor assembly (21) comprises sensors (D1, D2, D3, S1, S2, S3) which are designed to measure the positioning of the patient's body area (O) on the patient table, and at least some of the sensors are designed and arranged to measure the positioning of the body area (O) when they are attached to, on or under the body area (O). The invention also relates to a method for position determination, to an optical pressure sensor, to an optical position sensor and to a head restraint.
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique
A61B 5/11 - Mesure du mouvement du corps entier ou de parties de celui-ci, p.ex. tremblement de la tête ou des mains ou mobilité d'un membre
G01L 1/24 - Mesure des forces ou des contraintes, en général en mesurant les variations des propriétés optiques du matériau quand il est soumis à une contrainte, p.ex. par l'analyse des contraintes par photo-élasticité
G01L 11/02 - Mesure de la pression permanente, ou quasi permanente d'un fluide ou d'un matériau solide fluent par des moyens non prévus dans les groupes ou par des moyens optiques
G01R 33/34 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails de structure, p.ex. résonateurs
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A gantry tube for a medical imaging system. The gantry tube includes a first tube located within a second tube, wherein the first tube is oriented about a longitudinal axis of the system. The gantry tube also includes a plurality of wall elements that extend between the first and second tubes, wherein the walls and first and second tubes form a plurality of channels that extend in an axial direction substantially parallel to the longitudinal axis wherein each channel is configured to hold a detector of the system. A detector is inserted into or removed from an associated channel in an axial direction from either a first end or a second end of the gantry tube.
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique
A61B 6/00 - Appareils pour diagnostic par radiations, p.ex. combinés avec un équipement de thérapie par radiations
23.
DETERMINING COMPARABLE PATIENTS ON THE BASIS OF ONTOLOGIES
The invention relates to a computer-implemented method for determining a similarity measure, the similarity measure describing a similarity between a first patient and a second patient. The method is based on receiving a first patient data record and a second patient data record, the first patient data record being assigned to the first patient and the second patient data record being assigned to the second patient. Furthermore, a medical ontology is received or determined. In this context, the medical ontology is independent of the first patient data record and of the second patient data record. Furthermore, a patient ontology is determined on the basis of the medical ontology, and further on the basis of the first patient data record and/or the second patient data record. Furthermore, a similarity measure is determined on the basis of the patient ontology. Optionally, the similarity measure is moreover provided, the provision possibly encompassing storage, transmission and/or representation of the similarity measure. The invention furthermore relates to a determination system, a computer program product, and a computer-readable storage medium for determining a similarity measure, the similarity measure describing a similarity between a first patient and a second patient.
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G16H 50/70 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour extraire des données médicales, p.ex. pour analyser les cas antérieurs d’autres patients
24.
METHOD AND SYSTEM FOR AUTOMATIC DETECTION OF FREE INTRA-ABDOMINAL AIR
The present invention relates to a method and system for the detection of free intra-abdominal air. In particular, the invention relates to a (e.g. computer-implemented) method for the detection of free intra-abdominal air, comprising: - receiving input data, said input data comprising a medical imaging data set of an abdominal region of a patient, e.g. via a first interface; applying a trained function, wherein the output data is generated, providing the output data e.g. via a second interface.
The invention relates to an antenna arrangement for receiving radiofrequency signals in the frequency and power range of a magnetic resonance apparatus, comprising at least one signal conductor and a carrier element which is connected to the antenna arrangement. The carrier element is shaped according to at least one part of a set of teeth of an examination object and is able to be connected in interlocking fashion to the set of teeth of the patient in an application position. Further, the invention relates to a system comprising a magnetic resonance apparatus and an antenna arrangement, wherein the magnetic resonance apparatus is signal connected to the antenna arrangement and is embodied to receive radiofrequency signals from the antenna arrangement and to create image data of a set of teeth of the examination object. Furthermore, the invention relates to a method for carrying out a magnetic resonance measurement on a set of teeth of an examination object using an antenna arrangement, including the following steps: orienting the carrier element with the antenna arrangement relative to the set of teeth of the examination object, connecting the carrier element to the set of teeth of the examination object, and carrying out the magnetic resonance measurement on the set of teeth of the examination object.
G01R 33/34 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails de structure, p.ex. résonateurs
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique
26.
PROVIDING AN INDICATION REGARDING THE AFFLICTION OF A PATIENT WITH AN INFECTIOUS RESPIRATORY DISEASE BASED ON MAGNETIC RESONANCE IMAGING DATA
Embodiments of the invention generally relate to a computer- implemented method for providing output data comprising an indication regarding the affliction of a patient with an infectious respiratory disease, a computer-implemented method for providing a trained function, a providing system, a training system, a computer program and a computer-readable medium. The computer-implemented method for providing output data comprising an indication regarding the affliction of a patient with an infectious respiratory disease comprises the following steps: - receiving magnetic resonance imaging data acquired using a magnetic resonance imaging system, wherein the magnetic resonance imaging data comprise a lung region of the patient, - applying a trained function to the magnetic resonance imaging data, wherein output data are generated, wherein the trained function is based on an artificial neural network and the output data comprise an indication regarding the affliction of the patient with the infectious respiratory disease, - providing the output data.
G01R 33/56 - Amélioration ou correction de l'image, p.ex. par des techniques de soustraction ou d'établissement de moyenne
A61B 5/055 - Détection, mesure ou enregistrement pour établir un diagnostic au moyen de courants électriques ou de champs magnétiques; Mesure utilisant des micro-ondes ou des ondes radio faisant intervenir la résonance magnétique nucléaire [RMN] ou électronique [RME], p.ex. formation d'images par résonance magnétique
A61B 5/08 - Dispositifs de mesure pour examiner les organes respiratoires
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
27.
MACHINE-LEARNED NETWORK FOR MEDICAL ROBOT GENERATION FROM CONFIGURABLE MODULES
A generative adversarial network (GAN) (21, 24), or any other generative modeling technique, is used to learn (12) how to generate (68) an optimal robotic system given performance, operation, safety, or any other specifications. For instance, the specifications may be modeled (65) relative to anatomy to confirm satisfaction of anatomy-based or another task specific constraint. A machine-learning system, for instance neural network, is trained (12) to translate given specifications to a robotic configuration. The network may convert task-specific specifications into one or more configurations of robot modules into a robotic system. The user may enter (67) changes to performance in order for the network to estimate (62) appropriate configurations. The configurations may be converted (64) to estimated performance by another machine-learning system, for instance neural network, allowing modeling (65) of operation relative to the anatomy, such as anatomy based on medical imaging. The configuration satisfying the constraints from the modeling (65) may be assembled (69) and used.
G05B 13/00 - Systèmes de commande adaptatifs, c. à d. systèmes se réglant eux-mêmes automatiquement pour obtenir un rendement optimal suivant un critère prédéterminé
G06N 20/10 - Apprentissage automatique utilisant des méthodes à noyaux, p.ex. séparateurs à vaste marge [SVM]
B25J 9/08 - Manipulateurs à commande programmée caractérisés par des éléments de construction modulaires
B25J 19/00 - Accessoires adaptés aux manipulateurs, p.ex. pour contrôler, pour observer; Dispositifs de sécurité combinés avec les manipulateurs ou spécialement conçus pour être utilisés en association avec ces manipulateurs
28.
COMPENSATION OF ORGAN DEFORMATION FOR MEDICAL IMAGE REGISTRATION
Systems and methods for medical image registration are provided. A first input medical image and a second input medical image of one or more anatomical objects are received. For each respective anatomical object of the one or more anatomical objects, a region of interest comprising the respective anatomical object is detected in one of the first input medical image or the second input medical image, the region of interest is extracted from the first input medical image and from the second input medical image, and a motion distribution of the respective anatomical object is determined from one of the region of interest extracted from the first input medical image or the region of interest extracted from the second input medical image using a motion model specific to the respective anatomical object. The first input medical image and the second input medical image are registered based on the motion distribution of each respective anatomical object of the one or more anatomical objects to generate a fused image.
The invention relates to an ensemble of at least two X-ray contrast agents (I, K2). The ensemble comprises a first X-ray contrast agent (I) and a second X-ray contrast agent (K2). The second X-ray contrast agent (K2) has an X-ray absorption whose change between at least two different X-ray photon energies (E(1) E(2)) differs significantly from the change of the X-ray absorption of the first X-ray contrast agent (I) between the at least two different X-ray photon energies (E(1), E(2)). The invention also relates to an X-ray imaging method. In addition, the invention relates to an image reconstruction device (40). Furthermore, an X-ray imaging system (50) is disclosed.
The invention relates to an X-ray contrast agent. The X-ray contrast agent (K) has an X-ray absorption the change of which between at least two different X-ray photon energy levels (E(1), E(2)) differs significantly from the change in X-ray absorption of calcium between the at least two different X-ray photon energy levels (E(1), E(2)). The invention also relates to an X-ray imaging method. The invention additionally relates to an image reconstruction device (50). The invention further relates to an X-ray imaging system (60).
The present invention relates to a method of obtaining an enriched personalized population of a target polynucleotide using a synthetic single guide RNA (sgRNA) for an sgRNA- guided nucleic acid-binding protein, as well as to a method of obtaining a pool of personalized target-irrelevant synthetic single guide RNAs (sgRNAs) for a sgRNA-guided nucleic acid-binding protein. Also provided is a kit comprising a pool of sgRNAs obtainable by the methods of the invention, the use of a pool of sgRNAs obtainable by the methods of the invention and a method of monitoring a disease state.
For particularly quick and error-reduced navigation in vessel branches, a method is provided for visual support during navigation of a medical catheter introduced into a hollow organ system of a patient in a hollow organ branch, comprising the following steps: providing an, in particular pre-segmented, volume image of the hollow organ system and the hollow organ branch, which has been captured by means of an X-ray device; providing information relating to the geometric shape of the catheter tip; receiving a current projection image of the catheter tip, in particular by means of a cone beam X-ray device; registering the volume image and the projection image in the event that there is no pre-registration; determining the current position and current orientation of the catheter tip on the projection image based on the projection image; determining the relative position and relative orientation of the catheter tip in relation to the hollow organ branch; and displaying information relating to the determined relative position and/or relative orientation of the catheter tip in relation to the hollow organ branch.
In one aspect the invention relates to a computer-implemented method for providing a stroke information, the method comprising - Receiving computed tomography imaging data of an examination area of a patient, the examination area of the patient comprising a plurality of brain regions, at least one brain region of the plurality of brain regions being affected by a stroke, - Receiving brain atlas data, - Generating registered imaging data based on the computed tomography imaging data and the brain atlas data, the registered imaging data being registered to the brain atlas data, - Generating the stroke information regarding the stroke based on a set of algorithms and the registered imaging data, and - Providing the stroke information.
The invention relates to a computer-implemented method for the registration of images, comprising the following steps: a) receiving a first and at least one second image; b) displaying a graphic representation of the first image on a display unit; c) detecting a gaze direction of a user in relation to the graphic representation of the first image by means of a gaze direction detection unit; d) determining at least one pixel in the first image on the basis of the detected gaze direction; e) determining a region of interest in the first image on the basis of the at least one pixel; f) determining a region of interest of the at least one second image corresponding with the region of interest of the first image; g) registering the at least one second image with the first image on the basis of the region of interest of the first image and the corresponding region of interest of the at least one second image. The invention also relates to a device for the registration of images, a medical imaging device and a computer program product.
The present invention relates to methods of predicting a radiotherapy success in a method of treating a lung cancer of a patient, the use of specific markers for predicting a radiotherapy success in a method of treating a lung cancer of a patient, a database comprising the markers, and a computer program product for use in such a method.
C12Q 1/6886 - Produits d’acides nucléiques utilisés dans l’analyse d’acides nucléiques, p.ex. amorces ou sondes pour les maladies provoquées par des altérations du matériel génétique pour le cancer
A computer-implemented method, processor and computer- implemented storage medium for updating a boundary segmentation, the method comprising receiving image data and an original boundary segmentation comprising a plurality of boundary points. A plurality of edges in the image data is detected and used to generate an edge map. A confidence for a boundary point in the original boundary segmentation is computed where the confidence is based on a distance between the boundary point and an edge point associated with at least one of the plurality of edges of the edge map, and based on the confidence a classification of the boundary point is determined. An updated boundary segmentation based on the classification of the boundary point is generated and then output.
Systems and methods are provided for training an artificial intelligence model for detecting calcified portions of a vessel in an input medical image. One or more first medical images of a vessel in a first modality and one or more second medical image of the vessel in a second modality are received. Calcified portions of the vessel are detected in the one or more first medical images, The artificial intelligence model is trained for detecting calcified portions of the vessel in the input medical image in the second modality based on the one or more second medical images and the detected calcified portions of the vessel detected in the one or more first medical images.
Systems and methods for determining a 3D centerline of a vessel are provided. A current state observation of an artificial agent is determined based on one or more image view sets, each including 2D medical images of a vessel, a current position of the artificial agent in the 2D medical images, and a start position and a target position in the 2D medical images. Policy values are calculated for a plurality of actions for moving the artificial agent in 3D based on the current state observation using a trained machine learning model. The artificial agent is moved according to a particular action based on the policy values. The steps of determining, calculating, and moving are repeated for a plurality of iterations to move the artificial agent along a 3D path between the start position and the target position. The 3D centerline of the vessel is determined as the 3D path.
The invention relates to a mobile medical device, in particular a mobile C-arm X-ray device, comprising a device trolley which can be driven in at least two movement modes in a motor-supported manner, having at least one gripping element, which is provided for gripping by means of at least one human hand of an operator in order to move the device, and additionally having at least one sensor, which is arranged on the gripping element or in the direct vicinity thereof and is designed to detect measurement data that characterizes the type and/or location of the grip by means of the at least one human hand, an evaluating unit, which is designed to evaluate the measurement data with respect to the type and/or location of the grip and assign a movement mode of the device trolley, and a control unit for automatically setting the evaluated movement mode of the device trolley.
A61B 6/00 - Appareils pour diagnostic par radiations, p.ex. combinés avec un équipement de thérapie par radiations
B25J 13/02 - Moyens de commande à préhension manuelle
G01L 5/22 - Appareils ou procédés pour la mesure des forces, du travail, de la puissance mécanique ou du couple, spécialement adaptés à des fins spécifiques pour la mesure de la force appliquée aux organes de commande, p.ex. organes de commande des véhicules, détentes
The invention relates to a magnetic resonance fingerprinting method for an improved determination of local parameter values of an examination object. Embodiments relate to, for example, value ranges with different resolutions in the fingerprinting dictionary, switching a compensation gradient in order to lead the nulled moment of a read gradient to the value of null, ascertaining correction terms for reading trajectories used when capturing magnetic resonance fingerprinting data, switching gradients in order to neutralize the magnetization of the spin in the examination object prior to stimulating the spin in order to capture magnetic resonance fingerprinting data, using flip angles with a value of null while capturing the magnetic resonance fingerprinting data, comparing signal, wherein only real-value components of the signals of signal curves to be compared are compared, taking B1 data into consideration when ascertaining comparison signal curves, using a threshold when reconstructing data, using a fast group matching method when reconstructing data, or optimizing the sequence of reading trajectories when capturing the magnetic resonance fingerprinting data.
G01R 33/50 - Systèmes d'imagerie RMN basés sur la détermination des temps de relaxation
G01R 33/56 - Amélioration ou correction de l'image, p.ex. par des techniques de soustraction ou d'établissement de moyenne
G01R 33/561 - Amélioration ou correction de l'image, p.ex. par des techniques de soustraction ou d'établissement de moyenne par réduction du temps de balayage, c.à d. systèmes d'acquisition rapide, p.ex. utilisant des séquences d'impulsions écho-planar
G01R 33/565 - Correction de distorsions d'image, p.ex. dues à des inhomogénéités de champ magnétique
G01R 33/24 - Dispositions ou appareils pour la mesure des grandeurs magnétiques faisant intervenir la résonance magnétique pour la mesure de la direction ou de l'intensité de champs magnétiques ou de flux magnétiques
41.
PLUG-TYPE CONNECTOR PART WITH A HANDLE ELEMENT FOR STEERING THE MOVEMENT
A plug-type connector part is described. The plug-type connector part comprises a rear part and an insertion part attached to or integrally formed with the rear part. The insertion part extends from the rear part in a mating direction of the plug-type connector part, the insertion part comprising a plurality of contact elements. The plug-type connector part comprises a handle element attached to or integrally formed with the rear part. The handle element is located opposite of the insertion part and faces the insertion part, with an interspace between the handle element and the insertion part.
H01R 13/44 - Moyens pour empêcher l'accès aux contacts actifs
H01R 13/631 - Moyens additionnels pour faciliter l'engagement ou la séparation des pièces de couplage, p.ex. moyens pour aligner ou guider, leviers, pression de gaz pour l'engagement uniquement
H01R 12/91 - Dispositifs de couplage autorisant un mouvement relatif entre les pièces de couplage, p.ex. un flottement ou un auto-alignement
42.
SENSING DEVICE WITH AN ULTRASOUND SENSOR AND A LIGHT EMITTING GUIDING MEANS COMBINED IN A PROBE HOUSING AND METHOD FOR PROVIDING GUIDANCE
The invention relates to a sensing device (1) for providing guidance for a medical device (5), in particular a needle, comprising: - a probe housing (2), - an ultrasound sensor (3), which is at least partly surrounded by the probe housing (2), for acquiring target information concerning a medical target (6) by means of ultrasound (7), and - a guiding means (4) arranged at the probe housing (2) for guiding the medical device (5), in particular the needle, along a planned path (9) relative to the medical target (6). To provide a technique of guiding the medical device (5), which allows an easier handling it is envisaged that - the guiding means (4) comprises a path acquisition means (13) for acquiring the planned path (9), wherein - the guiding means (4) comprises a light unit (10) for emitting a light pattern (12) which indicates the planned path (9).
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
43.
SENSING DEVICE AND METHOD FOR TRACKING A NEEDLE BY MEANS OF ULTRASOUND AND A FURTHER SENSOR SIMULTANEOUSLY
The invention relates to a sensing device (1) for providing guidance for a medical device (5), in particular a needle, comprising - a probe housing (2) and - an ultrasound sensor (3), which is at least partly surrounded by the probe housing (2), for acquiring target information concerning a medical target (6) by means of ultrasound (7), - wherein the sensing device (1) is configured to provide the target information for providing guidance in positioning the medical device (5), in particular the needle, relative to the medical target (6). To improve the tracking of the medical device (5), in particular the needle, it is envisaged that - a sensor unit (4) which is directly arranged at the probe housing (2), wherein the sensor unit (4) is configured to acquire position data concerning a position of the medical device (5), in particular the needle, by means of an acquisition principle, which is different from the ultrasound sensor (3).
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
44.
SUSPENSION APPARATUS FOR SUPERCONDUCTING MAGNET, SUPERCONDUCTING MAGNET AND MAGNETIC RESONANCE IMAGING DEVICE
A suspension apparatus for a superconducting magnet, comprising a support tray (10) and at least two suspension assemblies (20). The support tray (10) has at least one through-hole (11) and comprises at least two mounting parts (15). The at least two suspension assemblies (20) pass through the support tray (10) via the through-hole (11). Each of the suspension assemblies (20) is connected to one of the mounting parts (15). The suspension apparatus is easy to install. Furthermore, a superconducting magnet comprising the suspension apparatus, and a magnetic resonance imaging device, are also provided.
G01R 33/3815 - Systèmes pour produire, homogénéiser ou stabiliser le champ magnétique directeur ou le champ magnétique à gradient utilisant des électro-aimants avec des bobines supraconductrices, p.ex. leurs alimentations
G01R 33/38 - Systèmes pour produire, homogénéiser ou stabiliser le champ magnétique directeur ou le champ magnétique à gradient
The present invention relates to an automatic organ program selection method, a storage medium, and an X-ray medical device. According to an implementation, an automatic organ program selection method for X-ray imaging comprises: acquiring an image of a person to be detected; performing organ detection based on the image of the person to be detected, so as to determine an organ to be detected; providing organ programs to be selected that correspond to the organ to be detected; and determining an organ program for the organ to be detected so as to perform X- ray imaging. The present invention can greatly reduce the time for setting a system, and reduce the impact of patient movement on determination of an organ program, thereby improving examination efficiency.
The invention relates to an anaesthesia procedure and associated anaesthetic equipment (3). In said procedure, a first respiratory gas (G1) is supplied to an anaesthetized patient (15) through a ventilator (3) with unidirectional flow or rapidly alternating flow direction. At least one adjustment parameter (F) of the ventilator (3) is controlled or regulated in such a manner that a current position (LA) of at least one body part (36) of the patient (15) is adjusted to a specified desired position (LS).
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
A61B 6/00 - Appareils pour diagnostic par radiations, p.ex. combinés avec un équipement de thérapie par radiations
47.
PATIENT POSITIONING DEVICE FOR AN X-RAY IMAGING APPARATUS
The invention relates to a patient positioning device (1, 6, 28, 35) for an x-ray imaging apparatus (23), comprising an x-ray-transparent patient positioning board (5) for positioning a patient (21) in a longitudinal direction (8), and at least one carrier device (3) at least partially supporting the patient positioning board (5). The patient positioning board (5) is subdivided into at least two partial boards (4), wherein each partial board (4) is mounted on a carrier device (3) assigned to the partial board (4). Each carrier device (3) has at least one pivot joint for pivoting the partial boards (4) about a transverse axis (20) which extents horizontally perpendicularly to the longitudinal direction (8).
A 3D shape (29) is reconstructed from a topogram (21). A generative network is machine trained. The generative network includes a topogram encoder (24) for inputting the topogram (21) and a decoder (28) to output the 3D shape (29) from the output of the decoder (28). For training, one or more other encoders (23, 26) are included, such as for input of a mask (20) and/or input of a 3D shape (22) as a regularlizer. The topogram encoder (24) and decoder (28) are trained with the other encoder or encoders (23, 26) outputting to the decoder (28). For application, the topogram encoder (24) and decoder (28) as trained, with or without the encoder (23) for the mask (20) and without the encoder (26) for the 3D shape (22), are used to estimate the 3D shape (29) for a patient from input of the topogram (21) for that patient.
The present invention relates to an automatic exposure control method for X-ray imaging, a storage medium and a medical device. According to one embodiment, an automatic exposure control method for X-ray imaging comprises: acquiring a visible light image of a subject under test, defining an initial region of interest (ROI) on the visible light image, pre-exposing the subject under test with a set pre-exposure dose to obtain a first image, defining an ROI on the first image based on the initial ROI, defining a reference pixel value based on the ROI, and calculating a main exposure dose for an actual exposure according to the reference pixel value. With the imaging quality guaranteed, the present invention can spare a physical automatic exposure control (AEC) chamber, and the number, positions and sizes of ROIs can be adjusted according to the actual requirements. The present invention is more flexible in patient positioning.
The present invention relates to a method of obtaining an enriched population of a target polynucleotide using a synthetic single guide RNA (sgRNA) for an sgRNA-guided nucleic acid-binding protein, as well as to a method of obtaining a pool of target-irrelevant synthetic single guide RNAs (sgRNAs) for a sgRNA-guided nucleic acid-binding protein. Also provided is a target polynucleotide and sgRNAs obtainable by the methods of the invention. Further envisaged is a kit comprising a pool of sgRNAs obtainable by the method of the invention, and the use of a pool of sgRNAs obtainable by the methods of the invention.
The present invention relates to a method of characterizing a target DNA polynucleotide using rolling circle amplification (RCA) and a synthetic single guide RNA (sgRNA) to identify and cleave the WT version of the target DNA polynucleotide. Also provided are characterization steps based on the use of a transmembrane pore and a DNA translocase enzyme controlling the movement of the DNA polynucleotide through the transmembrane pore. Further envisaged is a kit comprising one or more oligonucleotides specific for at least a portion of the target DNA polynucleotide, an sgRNA specific for the WT version of the target DNA polynucleotide and an sgRNA-guided nucleic acid-binding protein.
The invention relates to the transmission of a data set to a central data store. The invention is based on the fact that a data set is received by means of a data source. Furthermore, country information is optionally received by means of the data source. Furthermore, a data classification is determined on the basis of the data set by means of the data source. Furthermore, said data classification and optionally the country information are transmitted to a server by means of the data source. Furthermore, data transmission information from the server is received by means of the data source. The data transmission information is based on the data classification and optionally on the country information, and the data transmission information concerns the permissibility of the transmission of the data set. Furthermore, the data set is transmitted to the central data store depending on the data transmission information. The invention further relates to the provision of data transmission information, comprising the receipt of a data classification and optionally country information by means of a server, comprising the determination of data transmission information by means of the server, the data transmission information being based on the data classification and optionally on the country information, and comprising the provision of the data transmission information for a data source by means of the server.
The present invention relates to a method for detecting a target RNA polynucleotide by using a catcher polynucleotide which anneals to at least a portion of the target RNA polynucleotide, and a catalytically-inactive crRNA-guided (CRISPR RNA) RNA-binding protein which binds to the target RNA polynucleotide. Further envisaged is a kit for detecting a specific target RNA polynucleotide comprising inter alia one or more catcher polynucleotides complementary to at least a portion of the target RNA polynucleotide, a mature crRNA molecule which is specific for a target sequence on the target RNA polynucleotide and a catalytically-inactive crRNA-guided RNA-binding protein; as well as the use of these ingredients for the detection of the target RNA polynucleotide.
The invention relates to an automatic analyzer for analyzing a medical probe, said analyzer comprising an analysis cell for the probe, a piezo element, and an analysis device. The piezo element can be operated by applying a voltage and a frequency, and in the process an acoustic wave fuel is generated. A probe located in the analysis cell is located in the acoustic wave field when the piezo element is being operated.
A method for generating a medical result image (RESI) using a current image (CI), a target image (TI) and a reference image (REFI). All images depict at least partially the same body region of a patient (6). The method comprises the following steps: i. defining (S13; S23) at least one image segment (ISEG) within the target image, ii. registering (S14; S24) the reference image with the target image by establishing a registration matrix (REGMA) for each image segment within the target image, wherein the registration matrix is specific for the respective image segment, iii. detecting (S16; S26) a position of a surgical instrument (IPOS) in the current image, the position corresponding to an image segment of the target image, and iv. generating (S17; S27) the medical result image by fusing the current image and the reference image using the registration matrix as signed to the image segment according to the position of the surgical instrument within the current image. A computing unit thereof, a medical imaging apparatus comprising such unit and computer program product, computer readable medium executing such method are also provided.
A system operable to transmit healthcare data to a user device configured for use in analysing medical information. A directed graph representing at least one medical guideline is maintained in a database. The directed graph comprising a plurality of nodes connected by a plurality of directed edges. In some examples a directed graph is selected based on a medical condition and a context parameter. In some examples a directed graph is generated based on differences between versions of medical guidelines. A patient model may be maintained in a database and in some examples based on a combination of the directed graph and the patient model, further healthcare data is transmitted to the user device. The status of nodes and edges may be determined based on a combination of a directed graph and a patient model.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
57.
ENDOVASCULAR IMPLANT DECISION SUPPORT IN MEDICAL IMAGING
A vascular implant decision support uses a medical imaging system. A physics-based model of the endovascular implant is used to simulate deployment in a vessel model of a patient based on medical imaging. A porosity of the deployed implant and the simulation are used to determine a value for each of one or more hemodynamic parameters to support the decision for endovascular treatment. A machine-learned network uses patient-specific information to select the endovascular implant, placement, and/or other implant configuration used to simulate deployment and/or to predict outcome from deployment for the patient. The clinician may use the decision support to select among options for implanting and/or to confirm adequacy of a plan. Various of these approaches may be used alone or in combination.
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
A61B 34/10 - Planification, simulation ou modélisation assistées par ordinateur d’opérations chirurgicales
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
58.
A NOISE MEASURE FOR COPY NUMBER ANALYSIS ON TARGETED PANEL SEQUENCING DATA
The present invention relates to a method for determining the statistical noise level in the calculation of a subject's genetic copy number value in massively parallel nucleic acid sequencing data derived from a sample, as well as a method for determining a subject's genetic copy number value in massively parallel nucleic acid sequencing data derived from a sample and a method to determine a subject's genetic copy number value for stratifying the subject for cancer therapy.
A method is proposed for recording diagnostic measurement data of a knee of an examination object in knee imaging by means of a magnetic resonance device, comprising the following method steps: - Performance of an overview scan of the knee of the examination object, wherein overview measurement data is acquired in the overview scan, - Performance of various diagnostic scans of the knee of the examination object based on the acquired overview measurement data, wherein two-dimensional diagnostic measurement data is acquired in the various diagnostic scans.
G01R 33/54 - Systèmes de traitement du signal, p.ex. utilisant des séquences d'impulsions
G01R 33/561 - Amélioration ou correction de l'image, p.ex. par des techniques de soustraction ou d'établissement de moyenne par réduction du temps de balayage, c.à d. systèmes d'acquisition rapide, p.ex. utilisant des séquences d'impulsions écho-planar
The invention relates to a method for providing a medical imaging data set for radiotherapy planning of the patient by means of a medical imaging unit, comprising the following steps: providing patient-specific data about the patient, requesting a qualitative image state parameter and a contrast-based imaging state parameter which, together with the patient-specific data, define a requirement profile on an examination protocol, providing multiple original examination protocols which have multiple image state parameter profiles, determining at least one examination protocol template from the multiple examination protocol templates as the examination protocol, in such a way that the image state parameter profile of the determined at least one examination protocol template fulfils the requirement profile on the examination protocol, acquiring measurement data about the patient by means of the medical imaging unit in accordance with the examination protocol, and providing the medical imaging data set for the radiotherapy planning of the patient by using the measurement data, wherein the medical imaging data set has the quantitative image state parameter and the contrast-based image state parameter.
G16H 20/40 - TIC spécialement adaptées aux thérapies ou aux plans d’amélioration de la santé, p.ex. pour manier les prescriptions, orienter la thérapie ou surveiller l’observance par les patients concernant des thérapies mécaniques, la radiothérapie ou des thérapies invasives, p.ex. la chirurgie, la thérapie laser, la dialyse ou l’acuponcture
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
61.
DATA-DRIVEN ESTIMATION OF PREDICTIVE DIGITAL TWIN MODELS FROM MEDICAL DATA
Digital twin models of a patient, patient organ, or patient organ system from which biomarkers can be derived are used for clinical decision support. The individualization procedure also includes a predictive consideration (16) to improve the sensitivity and specificity of the digital-twin derived biomarker. In particular, during training, the predictive biomarker for which the individualized model is to be used is taken into account (16), which then accounts for the biomarker in application. The fitting (15) of the model for a specific patient accounts (16) for the prediction or model usage, resulting in estimating (14) biomarkers more optimized for the end use rather than just fit to the current baseline of the patient.
G16H 50/50 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour la simulation ou la modélisation des troubles médicaux
62.
3D DEPTH RECONSTRUCTION OF VESSELS IN 2D MEDICAL IMAGES
Systems and methods are provided for three dimensional depth reconstruction of vessels in two dimensional medical images. A medical image comprising braches of one or more vessels is received. A branch overlap image channel that represents a pixelwise probability that the branches overlap is generated. A set of branch orientation image channels are generated. Each branch orientation image channel is associated with one of a plurality of orientations. Each branch orientation image channel represents a pixelwise probability that the branches are oriented in its associated orientation. A multi-channel depth image is generated based on the branch overlap image channel and the set of branch orientation image channels. Each channel of the multi-channel depth image comprises portions of the branches corresponding to a respective depth.
Documenting timestamps within a blockchain The invention relates to a method and a system for determining a further data block, comprising receiving a further timestamp transaction with a first interface, wherein the further timestamp transaction comprises a hash of a dataset and a further verification time. The method furthermore comprises receiving a distributed ledger with the first inter- face, wherein the distributed ledger comprises data blocks. Furthermore, the method comprises determining a first time by querying a time server with a first computation unit. Fur- thermore, the method comprises performing a first check based on the first time and the further verification time with the first computation unit, and in the case of a positive first check, determining a further data block based on the distributed ledger with the first computation unit, wherein the further data block comprises the further timestamp transaction. In particular, a data block comprises ones or more timestamp transaction, and a timestamp transaction comprises a hash of a dataset and a verification time. The invention furthermore relates to methods and systems for providing a further timestamp transaction and for including a further data block into a distributed ledger. In particular, the distributed ledger can be a blockchain.
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
64.
BLOCKCHAIN-BASED DISTRIBUTION OF MEDICAL DATA RECORDS
Blockchain-based distribution of medical data records The invention relates to a method for providing an uniform resource locator, comprising the step of receiving a medical data record with an interface, wherein the medical data record is related to a patient, the step of determining the uni- form resource locater related to the medical data record with a computation unit, wherein the uniform resource locator comprises an authorization token based on the medical data record, and wherein the medical data record can be accessed by following the uniform resource locator, and the step of providing the uniform resource locator with the interface to the patient. The inventors recognized that by providing a uniform resource locator comprising an authorization token access to the medical data record can be granted fast and efficient, e.g. by a patient forwarding the uniform resource locator to another entity (e.g. a physician), while at the same time non-authorized entities cannot access the medical data record due to their lack of the suitable authorization token.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
65.
MEDICAL X-RAY DEVICE AND METHOD FOR AN ENERGY CALIBRATION
The invention relates to a medical x-ray device (1) having a first x-ray source (2) and a first counting x-ray detector (4). According to the invention, a. the first x-ray source (2) emits a beam bundle (7) with x-ray photons (8), b. the first counting x-ray detector (4) has a detection surface (11), wherein an angle (14) between the surface normal (13) of the detection surface (11) and a central beam (12) of the beam bundle (7) can be adjusted such that the central beam (12) of the beam bundle (7) does not run normal to the detection surface (11) in a calibration operation, and c. a calibration target (6) can be positioned such that calibration photons (9) are triggered in the calibration target (6) by means of the x-ray photons (8), and the calibration photons (9) are incident on at least one sub-region (15) of the detection surface (11). The sub-region (15) of the detection surface (11) is substantially shielded from x-ray photons (8).
The invention relates to a method for controlling the recording of ultrasounds, the dimensions (U1, U2, U3, U4) of a breast (O1, O2, O3, O4) being determined and an active region (23) of an ultrasound probe (21) of an ultrasound system (20) being controlled depending on the dimensions (U1, U2, U3, U4) determined. The invention further relates to a control device for carrying out said method, an ultrasound system (20) and an X-ray system (1).
Systems and methods are provided for classifying an abnormality in a medical image. An input medical image depicting a lesion is received. The lesion is localized in the input medical image using a trained localization network to generate a localization map. The lesion is classified based on the input medical image and the localization map using a trained classification network. The classification of the lesion is output. The trained localization network and the trained classification network are jointly trained.
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (USA)
SIEMENS HEALTHCARE GMBH (Allemagne)
Inventeur(s)
Grinstead, John
Frick, Matthew, A.
Deshpande, Vibhas
Kollasch, Peter
Amrami, Kimberly, K.
Chebrolu, Venkata, Veerendranadh
Felmlee, Joel, P.
Abrégé
Systems and methods for generating images with a magnetic resonance imaging ("MRI") system, in which the images have been corrected for receive coil nonuniformities are described. Improved data acquisition schemes for fat saturation are also described.
The present invention relates to an analyzer device for analyzing a sample comprising (i) at least two recursive structure elements; (ii) wherein each of the recursive structure elements has at least one connection to at least one of the other recursive structure elements; (iii) at least one measurement functionality; wherein said sample can be displaced between the recursive structure elements by a rotation of the analyzer device in a 3D-coordinate system. Also provided is a method for producing the analyzer device via 3D printing, a system comprising the device and a reagent pack, a method for in vitro diagnosis of viral or bacterial infections or cancer using the device, as well as the use of the analyzing device for the diagnostic analysis of a sample, in particular on the basis of the CRISPR/Cas system.
G01N 33/543 - Tests immunologiques; Tests faisant intervenir la formation de liaisons biospécifiques; Matériaux à cet effet avec un support insoluble pour l'immobilisation de composés immunochimiques
B01L 3/00 - Récipients ou ustensiles pour laboratoires, p.ex. verrerie de laboratoire; Compte-gouttes
The X-ray tube comprises an anode (40) having an interaction region (35) and a cooling contact (80), wherein the anode (40) has, in a region leading thermally from the interaction region (35) to the cooling contact (80), a non-disappearing and continuous spatial increase in thermal conductivity. The X-ray device has an X-ray tube of this kind. In the method for manufacturing an X-ray tube (20) of this kind or an X-ray device (10) of this kind, the region is formed by means of additive manufacture with a spatial change in the material composition or by means of a partially porous material and infiltration of the material.
The present invention relates to a method of screening for a cancer in a patient, an integrated method of screening for a cancer in a patient, a computer program product for carrying out the methods, as well as a medical imaging apparatus for carrying out the methods. With the present invention it is possible that the patient will obtain a more reliable result from a first medical imaging treatment.
G16H 30/40 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le traitement d’images médicales, p.ex. l’édition
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p.ex. DICOM, HL7 ou PACS
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
72.
MEDICAL DEVICE AND METHOD FOR OPERATING A MEDICAL DEVICE
The invention relates to a medical device (10, 20, 30) comprising: - at least one movably mounted and motor-adjustable component (11, 21, 31); - at least one drive unit (A) for adjusting the at least one component (11, 21, 31); - at least one motor control unit (MSt) associated with the drive unit (A); - at least one sensing unit (E) for sensing a position parameter (L) dependent on the position of the at least one component (11, 21, 31). According to the invention, a safety function is integrated in the motor control unit (MSt), which safety function limits at least one operating parameter (BP) associated with the motion of the at least one component (11, 21, 31) to be performed. An apparatus control unit (GSt) controls the drive unit (A) in dependence on the position parameter (L) in accordance with the safety function. The invention further relates to a method for operating a medical device (10, 20, 30) of this type.
The invention relates to an X-ray emitter (1) having an emitter housing (2), in which an X-ray tube (3) is arranged, which comprises a vacuum housing (4), in which at least one cathode and at least one rotating anode (5) are arranged, wherein, in a radiation emission region (11) in the vacuum housing (4), at least one first radiation emission window (8) is arranged and, in the emitter housing (2), at least one second radiation emission window (9) is arranged, characterized in that, in the rotation region of the rotating anode (5), at least one burst protection element (12) is arranged outside the vacuum housing (4) and inside the emitter housing (2), such that, in the event that the rotating anode (5) bursts, the kinetic energy of the fragments can be transferred to a region inside the emitter housing (2) and outside the radiation emission region (11) by means of the at least one burst protection element (12). Such an X-ray emitter (1) ensures further improved operational safety.
METHOD FOR CONTROLLING THE OPERATION OF A MEDICAL APPARATUS, OPERATING DEVICE, OPERATING SYSTEM, MEDICAL APPARATUS, COMPUTER PROGRAM AND ELECTRONICALLY READABLE DATA CARRIER
The invention relates to a method for controlling the operation of a medical apparatus (1), more particularly an image-capturing apparatus, wherein a wireless, hand-held, mobile operating device (5) having a touchscreen (10) is used and, for an examination process and/or treatment process of a patient (35) using the medical apparatus (1), a plurality of functions of a medical workflow are realized by means of the operating device (5), and wherein in order to determine a user interface to be displayed: - input data (22) describing the current operating situation are determined, said input data comprising patient data (23) regarding the patient (35), state-of-operation data (24) regarding the state of operation of the medical apparatus (1), position data (25) describing the position of the operating device (5) and/or of a patient (35) with respect to the medical apparatus (1), and workflow data (26) describing the current position in the medical workflow, - prediction data (28) describing a following operating action of the operator (34) and/or information needed next by the operator (34) are determined by means of an artificial-intelligence analysis algorithm (27), and - the user interface to be displayed is selected and/or modified in dependence on the prediction data (28) and then displayed.
G16H 40/67 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement à distance
A61B 6/00 - Appareils pour diagnostic par radiations, p.ex. combinés avec un équipement de thérapie par radiations
A61B 5/00 - Mesure servant à établir un diagnostic ; Identification des individus
The invention relates to an in-vitro method for determining a cell type of a white blood cell in a biological sample without labeling, wherein a microscopy apparatus images the cell and physical parameters of the cell are ascertained from the image of the cell by means of an automated image analysis, wherein the cell type of the white blood cell is determined on the basis of the physical parameters and on the basis of principal component analysis parameters (PCA parameters), wherein the principal component analysis parameters comprise linear combinations of at least some of the physical parameters.
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
G01N 33/49 - Analyse physique de matériau biologique de matériau biologique liquide de sang
76.
INSERTING A FURTHER DATA BLOCK INTO A FIRST LEDGER
The invention discloses a method for inserting a further data block into a first ledger, wherein the first ledger comprises data blocks, comprising the step of receiving a further medical dataset with an interface, the step of determining the further data block with a calculation unit, wherein the further data block comprises the further medical dataset and a further link information, wherein the further link information comprises a hash of at least one of the data blocks of the first ledger, and the step of inserting the further data block into the first ledger with the calculation unit.
G06F 21/64 - Protection de l’intégrité des données, p.ex. par sommes de contrôle, certificats ou signatures
H04L 9/32 - Dispositions pour les communications secrètes ou protégées; Protocoles réseaux de sécurité comprenant des moyens pour vérifier l'identité ou l'autorisation d'un utilisateur du système
H04L 29/06 - Commande de la communication; Traitement de la communication caractérisés par un protocole
G06Q 20/06 - Circuits privés de paiement, p.ex. impliquant de la monnaie électronique utilisée uniquement entre les participants à un programme commun de paiement
H01J 35/14 - Dispositifs de concentration, de focalisation ou d'orientation du rayon cathodique
H01J 35/24 - Tubes, dans lesquels le point d'impact du rayon cathodique sur l'anode ou l'anticathode est déplaçable par rapport à la surface de celles-ci
H05G 1/08 - Appareils à rayons X utilisant des tubes à rayons X; Circuits pour ces appareils - Détails électriques
78.
METHOD AND DEVICE FOR CHANGING THE SPATIAL INTENSITY DISTRIBUTION OF AN X-RAY BEAM
The invention relates to a method for changing a spatial intensity distribution of an x-ray beam, comprising the steps: producing an x-ray beam by means of an x-ray source; leading a beam path of the x-ray beam through a shaping filter having a plurality of plates, the shaping filter having a holding device, and the plurality of plates being arranged in the holding device in such a way that each plate has at least one straight line extending through the plate which is parallel to the further plates; orienting the plurality of plates relative to the beam path by controlled movement of at least some of the plurality of plates relative to each other and thereby changing the spatial intensity distribution of the x-ray beam. The invention further relates to a device designed to carry out a method of this type, to an irradiation assembly and to a medical imaging device.
G21K 1/04 - Dispositions pour manipuler des particules ou des rayonnements ionisants, p.ex. pour focaliser ou pour modérer utilisant des diaphragmes, des collimateurs utilisant des diaphragmes à ouverture variable, des obturateurs, des hacheurs
A61B 6/00 - Appareils pour diagnostic par radiations, p.ex. combinés avec un équipement de thérapie par radiations
A61B 6/02 - Dispositifs pour établir un diagnostic dans des plans différents successifs; Diagnostic stéréoscopique utilisant des radiations
G21K 1/10 - Dispositifs de diffusion; Dispositifs d'absorption
G21K 5/04 - Dispositifs d'irradiation avec des moyens de formation du faisceau
A61N 5/10 - Radiothérapie; Traitement aux rayons gamma; Traitement par irradiation de particules
79.
METHOD FOR THE POSITION PLANNING OF A CAPTURING SYSTEM OF A MEDICAL IMAGING DEVICE, AND MEDICAL IMAGING DEVICE
A method for the position planning of a capturing system of an imaging device with respect to a selectable capturing region of a patient, comprising the following steps: • capturing current position information of the capturing system and/or of the imaging device and/or setting information of a collimator of the imaging device, • capturing current position information of the patient, • determining a current course of an x-ray beam that can be emitted by the capturing system, • determining a current volume of intersection between the x-ray beam and the patient, in particular a patient envelope determined from the position information of the patient, and/or a current capturing region from the current course of the x-ray beam and a patient envelope, • displaying the current volume of intersection and/or the current capturing region as a virtual display element, • receiving a target volume of intersection and/or a target capturing region by manipulation of the virtual display element, and • determining a target position of the capturing system and/or of the imaging device and/or the setting of the collimator in such a way that, when the target position is assumed, the target volume of intersection and/or target capturing region becomes the current volume of intersection and/or current capturing region.
1211), wherein - the heat emission surface (21) comprises a specifiable number of individually controllable field effect emitter segments (22). Such an emission device has a longer service life while maintaining a constant image quality.
For non-invasive EP mapping, a sparse number of electrodes (e.g., 10 in a typical 12-lead ECG exam setting) are used to generate an EP map without requiring preoperative 3D image data (e.g. MR or CT). An imager (e.g., a depth camera) captures the surface of the patient and may be used to localize electrodes in any positioning on the patient. Two-dimensional (2D) x-rays, which are commonly available, and the surface of the patient are used to segment the heart of the patient. The EP map is then generated from the surface, heart segmentation, and measurements from the electrodes.
The invention relates to methods for setting up a microservice (MS), enhancing a ledger of microservices (MS) with a further microservice and accessing medical datasets (DS) stored in a microservice (MS), wherein the microservice (MS) contains the medical dataset (DS) in an encrypted form, wherein the microservice (MS) comprises an access logic (AL.1, AL.2) based on accessing entity information (AEI.1, AEI.2), and wherein the access logic (AL.1, AL.2) defines access conditions to the medical dataset (DS) and is configured to grant access to the medical dataset (DS) if the access conditions are fulfilled.
FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (Allemagne)
Inventeur(s)
Kara, Kerim
Stallkamp, Jan
Abrégé
The invention relates to a method (M) for acquiring and for altering a configuration of a number of objects (4) in a procedure room (6) for planning and for collision avoidance during a medical procedure, wherein each object (4) is represented by a virtual model (8), comprising a physical model (10) of said object (4) and a safety zone (12) around the physical model (10), the physical model (10) representing the configuration of said object (4) and the safety zone (12) representing a collision-prevention area for a movement of any of the objects (4) during a medical procedure, wherein the virtual models (8) of the objects (4) are placed at a position in a virtual model (22) of the procedure room (6), and wherein the configurations of the physical models (10, 26) during the medical procedure are computed and the configuration of the physical model (10) of the corresponding object (4) is altered, when a collision during the movement is determined. The invention further relates to a device (42) for executing said method (M).
G16H 40/63 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement d’équipement ou de dispositifs médicaux pour le fonctionnement local
G16H 40/20 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion ou l’administration de ressources ou d’établissements de soins de santé, p.ex. pour la gestion du personnel hospitalier ou de salles d’opération
G06T 19/00 - Transformation de modèles ou d'images tridimensionnels [3D] pour infographie
A system and method includes training of a first neural network, the first neural network defined by first metaparameters, evaluation of the performance of the trained first neural network, determination of a reward based on the performance, modification of the first metaparameters based on the reward to generate second metaparameters of a second neural network, the second neural network being larger than the first neural network, training of the second neural network, determination that the second neural network meets a performance goal, modification, in response to the determination that the second neural network meets a performance goal, that the second metaparameters to generate third metaparameters of a second neural network, the third neural network being smaller than the second neural network, evaluation of the performance of the third neural network, determination of a second reward based on the performance of the third neural network, modification of the third metaparameters to generate fourth metaparameters of a fourth neural network based on the reward, and evaluation of the performance of the fourth neural network.
A system and method includes determination of a projection axis associated with the two-dimensional projection image, generation of a second two-dimensional image from the three-dimensional image based on the projection axis, registration of the two-dimensional projection image with the second two-dimensional image, combination of the registered two- dimensional projection image with the three-dimensional image in a plane of the three- dimensional image substantially orthogonal to the projection axis, and display of the combined image.
The invention relates to a system (3) for tracking the position of a target object (2). A marker (10) which is arranged on the target object (2) and an additional control marker (11) are tracked by means of a tracking device (9) secured to the robot arm (5). The control marker (11) is arranged in a known specified three-dimensional positional relationship with the tracking device (9). During the tracking of the position of the target object (2), the specified three-dimensional positional relationship between the tracking device (9) and the control marker (11) is measured. In the event of a difference between the measured and the real specified three-dimensional positional relationship, a corresponding signal is generated depending on the difference.
A61B 34/20 - Systèmes de navigation chirurgicale; Dispositifs pour le suivi ou le guidage d'instruments chirurgicaux, p.ex. pour la stéréotaxie sans cadre
A61B 17/00 - Instruments, dispositifs ou procédés chirurgicaux, p.ex. tourniquets
A61B 90/00 - Instruments, outillage ou accessoires spécialement adaptés à la chirurgie ou au diagnostic non couverts par l'un des groupes , p.ex. pour le traitement de la luxation ou pour la protection de bords de blessures
87.
TRANSMISSION OF A CONFIDENTIAL MEDICAL DATA SET, IN PARTICULAR FOR A REMOTE DIAGNOSIS
The invention is based on the determination of a transaction data set, which comprises an encrypted data set, using a data source, wherein the encrypted data set is based on an encryption of the confidential data set. Furthermore, the transaction data set is transmitted from the data source to a central distribution unit, and a first processing condition is received by the central distribution unit, wherein the first processing condition is a condition for the processability of the confidential data set by one of multiple processing units. A receiving processing unit is selected from the processing units by means of the central distribution unit, said receiving processing unit satisfying the first processing condition, and the transaction data set is transmitted from the central distribution unit to the receiving processing unit. The confidential data set is determined by means of the receiving processing unit on the basis of a decryption of the encrypted data set, in particular the encrypted data set contained in the transaction data set.
H04L 29/06 - Commande de la communication; Traitement de la communication caractérisés par un protocole
G06F 21/62 - Protection de l’accès à des données via une plate-forme, p.ex. par clés ou règles de contrôle de l’accès
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
88.
METHOD FOR ANALYSING A MEDICAL IMAGING DATA SET, SYSTEM FOR ANALYSING A MEDICAL IMAGING DATA SET, COMPUTER PROGRAM PRODUCT AND A COMPUTER-READABLE MEDIUM
Method for analysing a medical imaging data set (11) comprising: - providing the medical imaging data set (11); - assigning a probability value (12) for a negative finding, in particular for a negative finding of a specific type of abnormality, to the medical imaging data set (11), wherein the probability value (12) is based on the image data set (11); and - providing the medical imaging data set (11) automatically either - to an output device (21) for analysing the medical imaging data set (11) or - to a device for storing (20) the medical imaging data set (11) based on the probability value (12).
G06F 19/00 - Équipement ou méthodes de traitement de données ou de calcul numérique, spécialement adaptés à des applications spécifiques (spécialement adaptés à des fonctions spécifiques G06F 17/00;systèmes ou méthodes de traitement de données spécialement adaptés à des fins administratives, commerciales, financières, de gestion, de surveillance ou de prévision G06Q;informatique médicale G16H)
G06K 9/62 - Méthodes ou dispositions pour la reconnaissance utilisant des moyens électroniques
89.
METHOD FOR SETTING A MEDICAL IMAGING PROTOCOL, SYSTEM FOR SETTING A MEDICAL INSTRUMENT, COMPUTER PROGRAM AND COMPUTER-READABLE MEDIUM
The present invention suggests a method for setting a medical imaging protocol (42), comprising: - providing (101) an information data set (14) assigned to a patient, wherein the information data set (14) includes an information about a provisional diagnostic finding regarding the patient; - assigning (102) a probability value (12) for a positive finding of the provisional diagnostic finding to the information data set (14); and - automatically setting the medical imaging protocol (2), wherein the medical imaging protocol (42) is adapted to the provisional diagnostic finding such that an analysis of a result of the medical imaging protocol changes the probability value (12).
G16H 40/40 - TIC spécialement adaptées à la gestion ou à l’administration de ressources ou d’établissements de santé; TIC spécialement adaptées à la gestion ou au fonctionnement d’équipement ou de dispositifs médicaux pour la gestion d’équipement ou de dispositifs médicaux, p.ex. pour planifier la maintenance ou les mises à jour
G16H 50/20 - TIC spécialement adaptées au diagnostic médical, à la simulation médicale ou à l’extraction de données médicales; TIC spécialement adaptées à la détection, au suivi ou à la modélisation d’épidémies ou de pandémies pour le diagnostic assisté par ordinateur, p.ex. basé sur des systèmes experts médicaux
G16H 30/20 - TIC spécialement adaptées au maniement ou au traitement d’images médicales pour le maniement d’images médicales, p.ex. DICOM, HL7 ou PACS
90.
MRI SCANNER WITH ACTIVE INTERFERENCE SUPPRESSION AND INTERFERENCE SUPPRESSION METHOD FOR AN MRI SCANNER
The invention relates to an MRI scanner and a method for operating said MRI scanner. The MRI scanner has a first receiving antenna for receiving a magnetic resonance signal from a patient in a patient tunnel, a second receiving antenna for receiving a signal having the Larmor frequency of the magnetic resonance signal, and a receiver. The second receiving antenna is located outside of the patient tunnel or near an opening thereof. The receiver has a signal connection to the first receiving antenna and the second receiving antenna and is designed to suppress an interference signal received by the second receiving antenna in a magnetic resonance signal received by the first receiving antenna.
G01R 33/36 - Systèmes d'excitation ou de détection, p.ex. utilisant des signaux radiofréquence - Détails électriques, p.ex. adaptations ou couplage de la bobine au récepteur
G01R 33/565 - Correction de distorsions d'image, p.ex. dues à des inhomogénéités de champ magnétique
The invention relates to a method for generating an evaluation image (2) of an interference image recorded by means of an optical interference method, comprising the following steps: calculating a first Fourier image by means of a Fourier transform of the interference image; calculating a second Fourier image (4) by means of fading out at least a first and second area (41, 42) within the first Fourier image, the first area (41) comprising the first diffraction order and the second area (42) comprising the minus first diffraction order, and the first and second areas (41, 42) being separate and having a different size; and calculating the evaluation image (2) by means of an opposite Fourier transform (142) of the second Fourier image (4). The invention further relates to a method for holographic microscopy of an object by means of an evaluation image (2) generated according to the invention.
The present invention relates to a method of producing tunneling electrodes using electrodeposition and forming of a short circuit, as well as tunneling electrodes produced thereby.
The present invention relates to an X-ray detector, an X-ray medical system and a medical system operating method. An X-ray detector provided in the present invention is used for receiving an X-ray, and comprises: a housing; a detector body, which may be accommodated in the housing; an electronic display layer, covering at least a partial region of a surface of the housing; and an electronic display layer drive apparatus, connected to the electronic display layer and capable of driving the electronic display layer to display dynamic information. The present invention is more convenient for operation by healthcare staff, increases examination efficiency, and improves patient experience. Moreover, the flexible e-ink layer selected in the present invention may be disposed in a light path of X-rays without having any effect on the image formed by the X-rays, and the image thereby obtained will be able to meet the image quality requirements without any need to perform additional image processing such as artefact elimination.
A61B 6/04 - Mise en position des patients; Lits inclinables ou similaires
A61B 6/00 - Appareils pour diagnostic par radiations, p.ex. combinés avec un équipement de thérapie par radiations
G02F 1/167 - Dispositifs ou dispositions pour la commande de l'intensité, de la couleur, de la phase, de la polarisation ou de la direction de la lumière arrivant d'une source lumineuse indépendante, p.ex. commutation, ouverture de porte ou modulation; Optique non linéaire pour la commande de l'intensité, de la phase, de la polarisation ou de la couleur basés sur le mouvement de translation des particules dans un fluide sous l’influence de l’application d’un champ caractérisés par l’effet électro-optique ou magnéto-optique par électrophorèse
Reconstructing 3-D vessel geometry of a vessel includes: receiving a plurality of 2-D rotational X-ray images of the vessel; extracting vessel centerline points for normal cross sections of each of the plurality of 2-D images; establishing a correspondence of the centerline points from a registration of the centerline points with a computed tomography (CT) 3-D centerline, the registration being an affine or deformable transformation; constructing a 3-D centerline vessel tree skeleton of the vessel from the centerline points of the 2-D images; constructing an initial 3-D vessel surface having a uniform radius normal to the 3-D centerline vessel tree skeleton; defining sample points based sampling on median radii to the 3-D centerline vessel tree skeleton of the initial 3-D vessel surface; and constructing a target 3-D vessel surface by deforming the initial vessel surface using the sample points to provide a reconstructed 3-D vessel geometry of the vessel.
A method (1) of enriching micro-organisms, in a metagenomics workflow, is disclosed. In an aspect of the invention, the method (1) includes obtaining said sample suspected to con- tain micro-organisms; concentrating said micro-organisms from said sample; and processing said micro-organisms to obtain genetic information specific to said micro-organisms. In an- other aspect of the invention, for concentrating said micro- organisms from said sample, the method (1) includes separat- ing plasma from said whole blood sample; selectively removing white blood cells from said plasma; and isolating said micro- organisms from said plasma after selectively removing said white blood cells.
C12Q 1/68 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismes; Compositions à cet effet; Procédés pour préparer ces compositions faisant intervenir des acides nucléiques
C12M 1/00 - Appareillage pour l'enzymologie ou la microbiologie
C12Q 1/24 - Méthodes d'échantillonnage, d'inoculation ou de développement d'un échantillon; Méthodes pour isoler physiquement un micro-organisme intact
The invention relates to a method and a local transmission unit for uploading a data record to a cloud data repository, wherein the method comprises the step of receiving a medical data record by a local transmission software, wherein the local transmission software comprises a core module and available plug-ins, wherein each available plug-in of the available plug-ins is associated with a remote application; the step of generating an anonymized data record based on the medical data record by a processing plug-in, wherein the processing plug-in is one of the available plug-ins; and the step of up-loading the anonymized data record to a cloud data repository, wherein the anonymized data record in the cloud data repository is accessible by the remote application associated with the processing plug-in.
G16H 10/60 - TIC spécialement adaptées au maniement ou au traitement des données médicales ou de soins de santé relatives aux patients pour des données spécifiques de patients, p.ex. pour des dossiers électroniques de patients
G06F 21/62 - Protection de l’accès à des données via une plate-forme, p.ex. par clés ou règles de contrôle de l’accès
98.
VISUALIZING AN IMAGE DATA SET WITH OBJECT-DEPENDENT FOCUSING PARAMETER
Method for visualizing an image data set, in particular a medical image data set, wherein the visualized data set displays a three-dimensional arrangement having at least a first object and a second object, comprising the steps: - providing a three-dimensional image data set including first voxels being assigned to the first object and second voxels being assigned to the second object; - identifying first voxels (11) of the-three dimensional image data; - determining a set of parameters for a volume rendering method, wherein the set of parameters includes a subset of parameters and a focusing parameter; - identifying primary rays (12) that impact on the first object and secondary rays that miss the first object; and - performing the volume rendering method (14), in particular a path tracing method, using the subset of parameters for visualizing the first object and the second object, wherein the focusing parameter used for the primary rays in the volume rendering method is different from the focusing parameter used for the secondary rays in the volume rendering method.
The invention relates to a method for providing result data which is suitable for use in planning the irradiation of a patient, a computing unit, a CT device and a computer program product. The method for providing result data which is suitable for use in planning the irradiation of a patient comprises the following method steps: - recording CT measurement data of the patient that has been acquired by a CT device having a quanta-counting X-ray detector, - further processing of the CT measurement data, wherein in the further processing of the CT measurement data a specific information content of the CT measurement data, which results from the use of the quanta-counting X-ray detector during the acquisition of the CT measurement data, is taken into account, wherein, in the further processing of the CT measurement data, result data is generated which is suitable for use in planning the irradiation of the patient, - providing the result data to an interface so that the result data can be used for planning the irradiation of the patient.
A system for performing adaptive focusing of a microscopy device comprises a microscopy device configured to acquire microscopy images depicting cells and one or more processors executing instructions for performing a method that includes extracting pixels from the microscopy images. Each set of pixels corresponds to an independent cell. The method further includes using a trained classifier to assign one of a plurality of image quality labels to each set of pixels indicating the degree to which the independent cell is in focus. If the image quality labels corresponding to the sets of pixels indicate that the cells are out of focus, a focal length adjustment for adjusting focus of the microscopy device is determined using a trained machine learning model. Then, executable instructions are sent to the microscopy device to perform the focal length adjustment.
G03H 1/00 - Procédés ou appareils holographiques utilisant la lumière, les infrarouges ou les ultraviolets pour obtenir des hologrammes ou pour en obtenir une image; Leurs détails spécifiques
G06K 9/00 - Méthodes ou dispositions pour la lecture ou la reconnaissance de caractères imprimés ou écrits ou pour la reconnaissance de formes, p.ex. d'empreintes digitales
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