Nitto Denko Corporation

Japan

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2022 2
2021 4
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Before 2019 69
IPC Class
A61K 9/70 - Web, sheet or filament bases 21
A61K 9/127 - Liposomes 12
A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin 12
A61K 31/713 - Double-stranded nucleic acids or oligonucleotides 10
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides 10
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Status
Pending 22
Registered / In Force 63
Found results for  patents

1.

LIPID NANOPARTICLE

      
Document Number 03194148
Status Pending
Filing Date 2021-10-01
Open to Public Date 2022-04-07
Owner
  • NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (Japan)
  • NITTO DENKO CORPORATION (Japan)
Inventor
  • Sato, Yusuke
  • Harashima, Hideyoshi
  • Hashiba, Kazuki
  • Taguchi, Masamitsu
  • Sakamoto, Sachiko
  • Shishido, Takuya
  • Otsu, Ayaka
  • Maeda, Yoshiki

Abstract

The present invention addresses the problem of providing lipid nanoparticles which function as gene transfer carriers capable of selective transfer to the liver or spleen. Lipid nanoparticles which contain a pH-sensitive cationic lipid represented by formula (I) [a represents an integer of 3-5; b represents 0 or 1; R1 and R2 each independently represent a group represented by general formula (A) (R11 and R12 each independently represent a straight-chain or branched-chain C2-15 alkyl group; c represents 0 or 1; v represents an integer of 4-12); and X represents a group represented by general formula (B) (d represents an integer of 0-3; and R3 and R4 each independently represent a C1-4 alkyl group or C2-4 alkenyl group, while R3 and R4 may form a 5- to 7-membered non-aromatic heterocycle) or represents a 5- to 7-membered non-aromatic heterocyclic group]. (I): (R1)(R2)C(OH)-(CH2)a-(O-CO)b-X. (A): (R11)(R12)-CH-(CO-O)c-(CH2)v-. (B): -(CH2)d-N(R3)(R4).

IPC Classes  ?

  • A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
  • A61K 47/44 - Oils, fats or waxes according to two or more groups of ; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
  • A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
  • C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle

2.

METHOD OF TREATING OIL-CONTAINING DISCHARGED WATER

      
Document Number 03191309
Status Pending
Filing Date 2021-07-20
Open to Public Date 2022-03-17
Owner NITTO DENKO CORPORATION (Japan)
Inventor Sato, Nagahisa

Abstract

The present invention involves processing, by using an oil resistance separation membrane, a to-be-processed liquid that is obtained from an oil-containing wastewater and that contains oil, to remove said oil therefrom.

IPC Classes  ?

  • B01D 61/02 - Reverse osmosis; Hyperfiltration
  • B01D 69/00 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
  • B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
  • B01D 69/10 - Supported membranes; Membrane supports
  • B01D 69/12 - Composite membranes; Ultra-thin membranes
  • B01D 71/32 - Polyalkenyl halides containing fluorine atoms
  • B01D 71/34 - Polyvinylidene fluoride
  • B01D 71/64 - Polyimides; Polyamide-imides; Polyester-imides; Polyamide acids or similar polyimide precursors
  • C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis

3.

COATING MATERIAL AND LAMINATE

      
Document Number 03182693
Status Pending
Filing Date 2021-04-30
Open to Public Date 2021-11-11
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Eguchi, Kenichi
  • Ishii, Aika
  • Ona, Haruka
  • Yano, Hikaru
  • Fujita, Hiroyuki

Abstract

The present invention pertains to a coating material containing a resin component and at least one oil component P, wherein below a predetermined temperature, the oil component P can be exuded from a coating layer cured and dried after the application of the coating material, the wetting parameter is 0.5 (J/cm3)1/2 or less, and the gel percentage in the coating layer is 30% or more.

IPC Classes  ?

  • C09D 5/00 - Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
  • C09D 7/65 - Additives macromolecular
  • C09J 7/22 - Plastics; Metallised plastics
  • C09J 7/38 - Pressure-sensitive adhesives [PSA]
  • C09D 201/00 - Coating compositions based on unspecified macromolecular compounds
  • C09K 3/18 - Materials not provided for elsewhere for application to surface to minimize adherence of ice, mist or water thereto; Thawing or antifreeze materials for application to surfaces

4.

BIOLOGICAL SENSOR

      
Document Number 03172283
Status Pending
Filing Date 2021-03-29
Open to Public Date 2021-10-07
Owner NITTO DENKO CORPORATION (Japan)
Inventor Odane, Chiharu

Abstract

This biosensor is attached to a living body to obtain signals from the living body, the biosensor comprising: a cover member; and a porous substrate having a porous structure and provided to the cover member on the living body side thereof. An attachment layer has the porous substrate and a first adhesive layer provided to the porous substrate on the living body side thereof, and the attachment layer: demonstrates a shear stress of 5×104 N/m2 to 65×104 N/m2 when deformed by 5% to 15% of the length of the attachment layer in a direction perpendicular to the thickness direction of the attachment layer; and has a moisture permeability of 65 (g/m2·day) to 4000 (g/m2·day).

IPC Classes  ?

  • A61B 5/256 - Wearable electrodes, e.g. having straps or bands
  • A61B 5/25 - Bioelectric electrodes therefor

5.

PATCH PREPARATION

      
Document Number 03172786
Status Pending
Filing Date 2021-02-18
Open to Public Date 2021-08-26
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Fujiwara, Kaiji
  • Imai, Hiroki
  • Tanaka, Tomoya
  • Nishimura, Masato

Abstract

The present invention addresses the problem of providing a patch preparation having excellent drug skin permeability and excellent adhesive properties. The present invention relates to a patch preparation characterized by containing, in an adhesive layer, a drug (other than tandospirone and pharmaceutically acceptable salts thereof), levulinic acid, and a propylene glycol fatty acid ester. The patch preparation has practical adhesive properties and is excellent in the skin permeability of the drug.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 47/12 - Carboxylic acids; Salts or anhydrides thereof
  • A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

6.

VENTILATION COMPONENT

      
Document Number 03167872
Status Pending
Filing Date 2021-01-14
Open to Public Date 2021-07-22
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Yano, Youzou
  • Kasagi, Tomoyuki
  • Takahashi, Takumi

Abstract

A ventilation component 1a is provided with an inner member 10, a ventilation film 20, and an outer member 30. The inner member 10 has an open tube structure and has a protruding portion 11 on the outer circumferential surface of the open tube structure. The ventilation film 20 covers one opening of the inner member. The outer member 10 is formed as a closed tube structure and has a locking portion for locking the protruding portion 11 at the inner circumferential surface of the closed tube structure. The inner member 10 is secured to the outer member 30 in a state in which the inner member 10 is inserted into the interior of the outer member 30 and the outer member 30 locks the protruding portion 11 by means of a locking portion 33. The ventilation component 1a can be secured to a protrusion 2p protruding in a tubular shape on the outer surface of a housing 2. When viewed in a planar view along an axial line A of the inner member 10 and the outer member 30, the ventilation component 1a satisfies the condition IH

IPC Classes  ?

  • F16K 24/00 - Devices, e.g. valves, for venting or aerating enclosures
  • H05K 5/06 - Hermetically-sealed casings

7.

STICK-ON BIOSENSOR

      
Document Number 03134253
Status Pending
Filing Date 2020-03-17
Open to Public Date 2020-10-01
Owner NITTO DENKO CORPORATION (Japan)
Inventor Masuda, Ryota

Abstract

Provided is a stick-on biosensor which is capable of obtaining good biological information. The stick-on biosensor includes: a pressure sensitive adhesive layer and an electrode part, said pressure sensitive adhesive layer having a stick-on surface that is attached to a subject; a base material layer that is provided on top of the opposite side of the pressure sensitive adhesive layer from the stick-on surface; and an electronic device that is provided on the base material layer and processes a biosignal obtained through the electrode part. The structure including the pressure sensitive adhesive layer, the electrode part, and the base material layer has a flexural rigidity of 0.010 [MPa·mm3/mm] or more, and the adhesive force with which the electrode part adheres to the subject is greater than 0.6 [N/cm2] and less than or equal to 5.0 [N/cm2].

IPC Classes  ?

  • A61B 5/25 - Bioelectric electrodes therefor

8.

DATA ACQUISITION DEVICE AND BIOSENSOR

      
Document Number 03134693
Status Pending
Filing Date 2020-03-17
Open to Public Date 2020-10-01
Owner
  • NITTO DENKO CORPORATION (Japan)
  • SPCHANGE, LLC. (Japan)
Inventor
  • Kamata, Takatsugu
  • Hirai, Yusaku
  • Ueda, Masayuki
  • Yoshioka, Ryoma

Abstract

The purpose of the present invention is to enable acquisition of data using less power. This data acquisition apparatus has an integrated circuit and an information processing device. The integrated circuit has: a first terminal to which a switch signal for master/slave switching is input at the start of acquisition of data; an A/D inverter for converting input analogue data to digital data; and an output terminal for outputting the digital data. In response to the switch signal, the integrated circuit is set as a master or slave. The information processing device has: a switching setting unit which, when the integrated circuit is a slave, sets the information processing device as a master, when the integrated circuit is a master, sets the information processing device as a slave, and generates the switch signal; a second terminal which is connected to the first terminal and outputs the switch signal; and an input terminal which is connected to the output terminal and to which the digital data is input. When the integrated circuit is set as a master on the basis of the switch signal input from the information processing device, the integrated circuit outputs the digital data from the output terminal.

IPC Classes  ?

  • G06F 17/40 - Data acquisition and logging
  • A61B 5/25 - Bioelectric electrodes therefor
  • A61B 5/28 - Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
  • A61B 5/291 - Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
  • A61B 5/30 - Input circuits therefor
  • G06F 3/05 - Digital input using the sampling of an analogue quantity at regular intervals of time
  • G06F 13/38 - Information transfer, e.g. on bus

9.

FILM

      
Document Number 03135105
Status Pending
Filing Date 2020-03-13
Open to Public Date 2020-10-01
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Matsukuma, Daisuke
  • Ona, Haruka
  • Nakamura, Yoshihiro
  • Fujita, Hiroyuki

Abstract

The objective of the present invention is to provide a film for increasing snow slippage and with which excellent prevention of snow adhesion and/or ice adhesion onto a structure can be achieved. This film includes as the outermost layer an oil-containing layer that contains an oil component within a resin. The oil component bleeds from the surface of the oil-containing layer at a predetermined temperature or lower. The surface of the oil-containing layer has a textured shape. In a 3.2 cm × 3.2 cm region on the surface of the oil-containing layer, the calculated mean height (Sa) is 4 µm or more.

IPC Classes  ?

  • B32B 27/00 - Layered products essentially comprising synthetic resin
  • B29C 59/04 - Surface shaping, e.g. embossing; Apparatus therefor by mechanical means, e.g. pressing using rollers or endless belts
  • B32B 3/30 - Layered products essentially comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar form; Layered products essentially having particular features of form characterised by a layer with cavities or internal voids characterised by a layer formed with recesses or projections, e.g. grooved, ribbed
  • C08J 5/16 - Manufacture of articles or materials having reduced friction
  • C08J 5/18 - Manufacture of films or sheets
  • C09K 3/18 - Materials not provided for elsewhere for application to surface to minimize adherence of ice, mist or water thereto; Thawing or antifreeze materials for application to surfaces
  • E04H 9/16 - Buildings, groups of buildings or shelters adapted to withstand or provide protection against abnormal external influences, e.g. war-like action, earthquake or extreme climate against adverse conditions, e.g. extreme climate, pests

10.

SOLAR CELL STRUCTURE AND METHOD FOR PREVENTING SNOW PILING ONTO SOLAR CELL STRUCTURE

      
Document Number 03135342
Status Pending
Filing Date 2020-03-27
Open to Public Date 2020-10-01
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Eguchi, Kenichi
  • Fujita, Hiroyuki
  • Sato, Masaaki

Abstract

This solar cell structure comprises: a panel structure having a solar cell panel; and a stand that supports the panel structure in an inclined state. The stand includes a support surface that supports the panel structure. The solar cell structure further comprises a cover that covers at least a region from the lower edge of the support surface in the direction of inclination to a prescribed area above the solar cell panel.

IPC Classes  ?

  • H02S 40/12 - Means for removing snow
  • H02S 20/10 - Supporting structures directly fixed to the ground

11.

GAS AND/OR CHEMICAL LIQUID INDICATOR

      
Document Number 03127094
Status Pending
Filing Date 2020-01-17
Open to Public Date 2020-07-23
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Nakamura, Koichi
  • Mohajeri, Nahid

Abstract

Described herein is an ammonia compound indicator comprising an adhesive and a chemochromic compound disposed therein. Also described are methods of making the aforedescribed elements and methods for indicating the presence of ammonia.

IPC Classes  ?

  • G01M 3/22 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for valves
  • G01M 3/04 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
  • G01M 3/20 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material
  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
  • G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
  • G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods using chemical indicators

12.

COATING MATERIAL AND FILM

      
Document Number 03118554
Status Pending
Filing Date 2019-11-11
Open to Public Date 2020-05-14
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Kotake, Shinya
  • Matsukuma, Daisuke
  • Eguchi, Kenichi
  • Ishii, Aika
  • Fujita, Hiroyuki

Abstract

The purpose of the present invention is to provide products, in particular, a coating material, capable of preventing icing and/or snow accretion. The coating material comprises a first oil ingredient, a second oil ingredient, and a first resin precursor, which is a precursor of a resin ingredient. Curing the first resin precursor which contains the first and second oil ingredients gives an oil-containing resin layer comprising the first and second oil ingredients and the resin ingredient. The second oil ingredient constitutes a low-temperature separable oil ingredient which, when the temperature declines to or below a given value, can separate from the first-oil-ingredient phase to ooze out of the oil-containing resin layer.

IPC Classes  ?

  • C09D 201/00 - Coating compositions based on unspecified macromolecular compounds
  • C09D 7/65 - Additives macromolecular

13.

SHEET BODY

      
Document Number 03118553
Status Pending
Filing Date 2019-11-11
Open to Public Date 2020-05-14
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Eguchi, Kenichi
  • Kotake, Shinya
  • Matsukuma, Daisuke
  • Ishii, Aika
  • Fujita, Hiroyuki

Abstract

The purpose of the present invention is to provide a sheet body that has an improved ice-accretion and/or snow-accretion inhibitory function. This sheet body comprises at least: an oil-containing resin layer that is in the form of a solid and that contains an oil; and an oil-permeable superficial resin layer which has a higher abrasion resistance than the oil-containing resin layer and which is laminated on one surface of the oil-containing resin layer. The oil contained in the oil-containing resin layer comprises a low-temperature exudative oil component that is capable of exuding from the oil-containing resin layer when the temperature drops to a level equal to or lower than a prescribed value, while the superficial resin layer exhibits oil permeability that allows the low-temperature exudative oil component exuding from the oil-containing resin layer to permeate the superficial resin layer up to a surface that is situated on the side opposite to the oil-containing resin layer.

IPC Classes  ?

  • B32B 27/18 - Layered products essentially comprising synthetic resin characterised by the use of special additives
  • B32B 7/022 - Mechanical properties
  • B32B 27/00 - Layered products essentially comprising synthetic resin
  • E04H 9/16 - Buildings, groups of buildings or shelters adapted to withstand or provide protection against abnormal external influences, e.g. war-like action, earthquake or extreme climate against adverse conditions, e.g. extreme climate, pests

14.

SHEET FOR BIOSENSOR

      
Document Number 03061595
Status Pending
Filing Date 2018-01-26
Open to Public Date 2019-10-25
Owner NITTO DENKO CORPORATION (Japan)
Inventor Yoshioka, Ryoma

Abstract

A biosensor sheet includes a pressure-sensitive adhesive layer for attaching to a surface of a living body, and a probe disposed on the pressure-sensitive adhesive layer, wherein the probe has an exposure region in which the pressure-sensitive adhesive layer is exposed.

IPC Classes  ?

  • A61B 5/257 - Means for maintaining electrode contact with the body using adhesive means, e.g. adhesive pads or tapes
  • A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons

15.

INTERNAL PRESSURE ADJUSTMENT MEMBER AND ELECTRICAL COMPONENT FOR TRANSPORT EQUIPMENT

      
Document Number 03085286
Status Pending
Filing Date 2018-12-11
Open to Public Date 2019-06-20
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Uemura, Kou
  • Tezuka, Teppei
  • Nishiyama, Satoshi
  • Kasagi, Tomoyuki

Abstract

Provided is an internal pressure adjustment member for attaching to the outer surface of a case, that: has high air permeability even when the pressure difference that may occur between inside and outside of the attachment case is small; and reduces damage and air permeability deterioration caused by flying dirt and mud. This internal pressure adjustment member comprises: a filter including a net- or mesh-shaped support layer and first and second polytetrafluorethylene (PTFE) porous membranes laminated on the support layer so as to sandwich the support layer, said filter having the first PTFE porous membrane exposed on one surface and the second PTFE porous membrane exposed on the other surface; and an adhesive section formed on said one surface of the filter and being for attaching the filter to the outer surface of the case. The average pore diameter of the first and second PTFE porous membranes is at least 2.0 µm, respectively, the thickness of the filter is no more than 140 µm, and the density of the filter is no more than 0.60 g/cm3.

IPC Classes  ?

  • H05K 5/06 - Hermetically-sealed casings
  • F21S 45/30 - Ventilation or drainage of lighting devices
  • B01D 39/16 - Other self-supporting filtering material of organic material, e.g. synthetic fibres
  • B01D 69/10 - Supported membranes; Membrane supports
  • B01D 69/12 - Composite membranes; Ultra-thin membranes
  • B01D 71/36 - Polytetrafluoroethene
  • F21V 31/03 - Gas-tight or water-tight arrangements with provision for venting

16.

FUSOGENIC COMPOUNDS FOR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES

      
Document Number 03081758
Status Pending
Filing Date 2018-11-06
Open to Public Date 2019-05-09
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ying, Wenbin
  • Tsang, Kwok Yin
  • Majeti, Bharat
  • Gaudette, John
  • Adami, Roger
  • Bai, Hao
  • Tsang, Kwok

Abstract

This invention includes fusogenic compounds, and compositions and methods of use thereof. The fusogenic compounds can be used for making nanoparticle compositions for use in biopharmaceuticals and therapeutics. More particularly, this invention relates to compounds, compositions and methods for providing nanoparticles to incorporate or encapsulate active agents, to deliver and distribute the active agents to cells, tissues, organs, and subjects.

IPC Classes  ?

  • C07C 237/22 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
  • A61K 9/127 - Liposomes
  • A61K 9/14 - Particulate form, e.g. powders
  • A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
  • A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
  • C07D 207/14 - Nitrogen atoms not forming part of a nitro radical
  • C07D 211/32 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • C12N 15/87 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
  • C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle

17.

SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE

      
Document Number 03055193
Status In Force
Filing Date 2018-03-01
Open to Public Date 2018-09-07
Grant Date 2022-10-18
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Zheng, Shijun
  • Kitahara, Isamu
  • Yamashiro, Yuji
  • Lin, Weiping
  • Ericson, John
  • Siddiqui, Ozair
  • Hsieh, Wanyun
  • Wang, Peng
  • Bartels, Craig Roger
  • Kobuke, Makoto
  • Noumi, Shunsuke

Abstract

Described herein is a graphene and polyvinyl alcohol based multilayer composite membrane that provides selective resistance for solutes to pass the membrane while providing water permeability. A selectively permeable membrane comprising a crossiinked graphene with a polyvinyl alcohol and silica-nanoparticle layer that can provide enhanced salt separation from water, methods for making such membranes, and methods of using the membranes for dehydrating or removing solutes from water are also described.

IPC Classes  ?

  • B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
  • B01D 69/10 - Supported membranes; Membrane supports
  • B01D 69/12 - Composite membranes; Ultra-thin membranes
  • B01D 69/14 - Dynamic membranes
  • B01D 71/02 - Inorganic material
  • B01D 71/56 - Polyamides, e.g. polyester-amides
  • B01D 61/02 - Reverse osmosis; Hyperfiltration

18.

SKIN FIBROSIS TREATMENT AGENT

      
Document Number 03041853
Status Pending
Filing Date 2017-11-01
Open to Public Date 2018-05-11
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Teshima, Takanori
  • Hashimoto, Daigo
  • Niitsu, Yoshiro
  • Minomi, Kenjiro

Abstract

The present invention relates to: a carrier for delivering a retinoid-containing substance used by extracellular-matrix-producing cells in the skin; a skin fibrosis treatment agent using said carrier; a preparation kit for said treatment agent; a production method for said carrier; and a production method for said treatment agent.

IPC Classes  ?

  • A61K 47/08 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • A61K 9/127 - Liposomes
  • A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
  • A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
  • A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
  • A61P 17/00 - Drugs for dermatological disorders

19.

AGENT FOR INDUCING CELL DEATH, AGENT FOR SUPPRESSING CELL PROLIFERATION, AND PHARMACEUTICAL COMPOSITION USED FOR TREATMENT OF DISEASE RESULTING FROM ABNORMAL CELL PROLIFERATION

      
Document Number 03028934
Status In Force
Filing Date 2017-06-23
Open to Public Date 2017-12-28
Grant Date 2021-06-08
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Tanaka, Hiroyuki
  • Minomi, Kenjirou

Abstract

It becomes possible to induce cell death of cancer cells and inhibit cell proliferation of cancer cells. A medicinal agent capable of inhibiting both of GST-p and MRPL17 is contained as an active ingredient, or a medicinal agent capable of inhibiting GST-p and a medicinal agent capable of inhibiting MRPL17 are contained as active ingredients.

IPC Classes  ?

  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61P 35/00 - Antineoplastic agents
  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers

20.

SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE

      
Document Number 03024857
Status In Force
Filing Date 2017-05-19
Open to Public Date 2017-11-23
Grant Date 2021-01-19
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Zheng, Shijun
  • Kitahara, Isamu
  • Siddiqui, Ozair
  • Yamashiro, Yuji
  • Lin, Weiping
  • Ericson, John
  • Romero, Rebecca
  • Wang, Peng
  • Noumi, Shunsuke
  • Bartels, Craig Roger
  • Hsieh, Wanyun
  • Hirose, Masahiko
  • Kobuke, Makoto

Abstract

Described herein is a crosslinked graphene based composite membrane that provides selective resistance to fluids solutes while providing water permeability, such as a selectively permeable membrane comprising a crosslinked graphene with a polyvinyl alcohol and silica-nanoparticle layer that can provide enhanced water separation. Also described herein are methods for making such membranes and methods of using the membranes for dehydrating or removing solutes from water.

IPC Classes  ?

  • B01D 71/56 - Polyamides, e.g. polyester-amides
  • B01D 61/02 - Reverse osmosis; Hyperfiltration
  • B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
  • B01D 69/10 - Supported membranes; Membrane supports
  • B01D 69/12 - Composite membranes; Ultra-thin membranes
  • B01D 69/14 - Dynamic membranes
  • B01D 71/02 - Inorganic material

21.

FUNCTIONALIZED LAMINATED OPTICAL ELEMENT WITH IMPROVED EDGING RESISTANCE

      
Document Number 03019346
Status In Force
Filing Date 2016-03-29
Open to Public Date 2017-10-05
Grant Date 2023-07-18
Owner
  • ESSILOR INTERNATIONAL (France)
  • NITTO DENKO CORPORATION (Japan)
Inventor
  • Coue, Violaine
  • Berger, Catherine
  • Desousa, Manuela
  • Suzuki, Tatsuya
  • Kamiya, Katsuhiko
  • Shigetomi, Kiyoe
  • Hoshino, Shinji
  • Nakayama, Junichi

Abstract

The invention relates to a functionalized laminated optical element comprising: - An optical base element; - A functional film structure consisting of a single layer or a multilayer structure; - A layer of a pressure-sensitive adhesive of optical quality, placed between one surface of the optical base element and the functional film structure so as to permanently retain said functional film structure on the surface of the optical base element. Said functionalized laminated optical element maintains its integrity after typical processing of an optical article which includes wheel edging. More particularly the invention relates to the use of a specific adhesive system for improving the wheel edging resistance of functionalized laminated optical element. The functional laminated optical may be an ophthalmic lens.

IPC Classes  ?

  • B23B 7/12 - Automatic or semi-automatic machines for turning of workpieces
  • B32B 7/12 - Interconnection of layers using interposed adhesives or interposed materials with bonding properties
  • G02B 1/10 - Optical coatings produced by application to, or surface treatment of, optical elements

22.

SIRNA STRUCTURES FOR HIGH ACTIVITY AND REDUCED OFF TARGET

      
Document Number 03005937
Status In Force
Filing Date 2016-12-12
Open to Public Date 2017-06-22
Grant Date 2021-11-09
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ying, Wenbin
  • Minomi, Kenjirou
  • Harborth, Jens
  • Cina, Cima
  • Zheng, Jane
  • Vaish, Narendra

Abstract

This invention provides compounds, compositions and methods for modulating the expression of target genes using RNA interference. RNAi structures and molecules of this invention can be used for modulating or silencing the expression of genes, with high levels of RNAi activity and reduced off target actions. Advantageous structures include siRNAs targeted to any gene having one or more 2'-deoxy nucleotides located in the seed region. The RNA interference molecules can be used in methods for preventing or treating diseases.

IPC Classes  ?

  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
  • C12N 15/11 - DNA or RNA fragments; Modified forms thereof

23.

SELECTIVELY PERMEABLE GRAPHENE OXIDE MEMBRANE

      
Document Number 03008827
Status In Force
Filing Date 2016-12-15
Open to Public Date 2017-06-22
Grant Date 2021-05-18
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Zheng, Shijun
  • Kitahara, Isamu
  • Kobuke, Makoto
  • Wang, Peng
  • Bartels, Craig Roger
  • Yamashiro, Yuji
  • Hirose, Masahiko
  • Noumi, Shunsuke
  • Lin, Weiping

Abstract

Described herein is a graphene material based membrane that provides selective resistance for solutes or gas while providing water permeability. A selectively permeable membrane comprising graphene oxide, reduced graphene oxide, and also functionalized or crosslinked between the graphene, that provides enhanced salt separation from water or gas permeability resistance, methods for making such membranes, and methods of using the membranes for dehydrating or removing solutes from water are also described.

IPC Classes  ?

  • B01D 71/02 - Inorganic material
  • B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
  • B01D 69/12 - Composite membranes; Ultra-thin membranes
  • B01D 69/14 - Dynamic membranes

24.

AIR FILTER MEDIUM, AIR FILTER PACK, AND AIR FILTER UNIT

      
Document Number 02999397
Status In Force
Filing Date 2016-09-30
Open to Public Date 2017-04-06
Grant Date 2022-06-14
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niki, Takashi
  • Mori, Masaaki
  • Wada, Shiho
  • Daimon, Atsushi

Abstract

This air filter material (10) comprises a first polytetrafluoroethylene (PTFE) porous membrane (1) and a second PTFE porous membrane (2). Fibers included in the first PTFE porous membrane (1) have an average fiber diameter of 0.24-0.45 µm, whereas fibers included in the second PTFE porous membrane (2) have an average fiber diameter of 0.04-0.23 µm. The air filter material (10) has a first main surface (11) and a second main surface (12), and the first PTFE porous membrane (1) and the second PTFE porous membrane (2) are disposed such that an airstream flowing from the first main surface (11) to the second main surface (12) passes through the first PTFE porous membrane (1) and the second PTFE porous membrane (2) in this order.

IPC Classes  ?

  • B01D 71/36 - Polytetrafluoroethene
  • B01D 39/16 - Other self-supporting filtering material of organic material, e.g. synthetic fibres
  • B01D 46/52 - Particle separators, e.g. dust precipitators, using filters embodying folded material
  • B01D 63/14 - Pleat-type membrane modules

25.

SELECTIVELY PERMEABLE GRAPHENE OXIDE/ POLYVINYL ALCOHOL MEMBRANE FOR DEHYDRATION

      
Document Number 02998153
Status In Force
Filing Date 2016-09-09
Open to Public Date 2017-03-16
Grant Date 2021-12-14
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Zheng, Shijun
  • Wang, Peng
  • Lin, Weiping
  • Romero, Rebecca
  • Kitahara, Isamu

Abstract

Described herein is a selectively permeable membrane comprising a graphene oxide and a polyvinyl alcohol on a support that provides high moisture permeability and low gas permeability. The methods for making these selectively permeable membranes and related devices are also described.

IPC Classes  ?

26.

COMPOSITIONS AND METHODS FOR NANOPARTICLE LYOPHILE FORMS

      
Document Number 02992849
Status In Force
Filing Date 2016-07-22
Open to Public Date 2017-01-26
Grant Date 2023-06-13
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ying, Wenbin
  • Adami, Roger
  • Wang, Yuwei
  • Yin, Haiqing
  • Wang, Liping
  • Liu, Dong

Abstract

This invention provides compositions for making a solid lyophile of one or more nucleic acid active agents, which can be reconstituted as a drug product. The composition can include an aqueous suspension of lipid nanoparticles in a pharmaceutically acceptable solution, wherein the lipid nanoparticles encapsulate one or more nucleic acid active agents, a dextrin compound, and a saccharide compound. The nucleic acid active agents can be RNAi molecules capable of mediating RNA interference, as well as other RNAs and oligonucleotides.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form

27.

IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREFOF

      
Document Number 02990668
Status Pending
Filing Date 2016-06-23
Open to Public Date 2016-12-29
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ying, Wenbin
  • Adami, Roger
  • Bai, Hao
  • Gaudette, John
  • Majeti, Bharat
  • Nukui, Seiji
  • Tsang, Kwok Yin
  • Wang, Hai
  • Yin, Haiqing

Abstract

This invention includes ionizable compounds, and compositions and methods of use thereof. The ionizable compounds can be used for making nanoparticle compositions for use in biopharmaceuticals and therapeutics. More particularly, this invention relates to compounds, compositions and methods for providing nanoparticles to encapsulate active agents, to deliver and distribute the active agents to cells, tissues, organs, and subjects.

IPC Classes  ?

  • C07C 237/08 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
  • A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
  • C07C 233/18 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
  • C07C 235/08 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
  • C07C 333/04 - Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
  • C07D 205/04 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
  • C07D 207/12 - Oxygen or sulfur atoms
  • C07D 211/42 - Oxygen atoms attached in position 3 or 5
  • C07D 295/15 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
  • C07F 9/10 - Phosphatides, e.g. lecithin

28.

PATCH PREPARATION

      
Document Number 02933509
Status Pending
Filing Date 2016-06-17
Open to Public Date 2016-12-17
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Tachikawa, Yu
  • Ameyama, Satoshi
  • Abe, Eriko
  • Nakamura, Tetsuya
  • Urushihara, Naoko
  • Ishikura, Jun
  • Aoyagi, Kazuhiro
  • Inoue, Yoshitaka
  • Yokouchi, Akira
  • Tanaka, Tomoya

Abstract

A patch preparation capable of inhibiting a deviation in pressure-sensitive adhesive properties of a pressure-sensitive adhesive layer even elapsing a long period of time until it is used after production and capable of keeping favorable pressure-sensitive adhesive properties is provided. The patch preparation includes a support and a pressure-sensitive adhesive layer formed on one surface of the support, and the pressure-sensitive adhesive layer includes: (A) a polymer prepared by copolymerizing monomer components including a hydroxyl group-containing monomer and an alkyl (meth)acrylate monomer; (B) a polymer prepared by copolymerizing monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer; and (C) a basic drug, provided that bisoprolol and a salt thereof are excluded.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

29.

PRESSURE-SENSITIVE ADHESIVE COMPOSITION

      
Document Number 02933071
Status In Force
Filing Date 2016-06-15
Open to Public Date 2016-12-16
Grant Date 2023-09-26
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Suzuki, Tatsuya
  • Kamiya, Katsuhiko
  • Shigetomi, Kiyoe
  • Hoshino, Shinji

Abstract

Provided is a PSA composition for forming a PSA comprising a (meth)acrylic polymer, comprising, as monomeric components constituting the (meth)acrylic polymer: (A) a C2-18 alkyl (meth)acrylate, (B) an alicyclic monomer, and (C) a monomer having at least either a hydroxyl group or a carboxyl group. The average number of carbons of alkyl group in the (A) is 8 or less. The monomeric components comprise the (C) at 3 % by weight or greater while the weights Wb and Wc of the (B) and (C) satisfy a relationship 0.8 <= Wb/Wc.

IPC Classes  ?

  • C09J 133/08 - Homopolymers or copolymers of acrylic acid esters

30.

CELL DEATH INDUCING AGENT FOR CELLS HAVING BRAF GENE MUTATION, GROWTH SUPPRESSING AGENT FOR SAME CELLS AND PHARMACEUTICAL COMPOSITION FOR THERAPY OF DISEASES CAUSED BY GROWTH DEFECT OF SAME CELLS

      
Document Number 02982643
Status Pending
Filing Date 2016-04-15
Open to Public Date 2016-10-20
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Nishita, Hiroki

Abstract

The present invention induces cell death and/or inhibits cell proliferation for cells having a mutation in the BRAF gene. The present invention includes, as an active ingredient, a drug inhibiting GST-p.

IPC Classes  ?

31.

CELL DEATH-INDUCING AGENT, CELL GROWTH-INHIBITING AGENT, AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DISEASE CAUSED BY ABNORMAL CELL GROWTH

      
Document Number 02972209
Status In Force
Filing Date 2015-12-24
Open to Public Date 2016-06-30
Grant Date 2023-11-14
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Tanaka, Hiroyuki
  • Minomi, Kenjirou
  • Niitsu, Yoshiro

Abstract

The present invention induces cell death, and suppresses cell growth, in cancer cells. The invention includes as active ingredients a drug for suppressing GST-p and a drug for suppressing both GST-p and suppressing homeostasis- and maintenance-related proteins exhibiting synthetic lethality.

IPC Classes  ?

  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
  • A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
  • A61P 35/00 - Antineoplastic agents
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms

32.

RNA INTERFERENCE AGENTS FOR GST-PI GENE MODULATION

      
Document Number 02971881
Status In Force
Filing Date 2015-12-28
Open to Public Date 2016-06-30
Grant Date 2023-04-04
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ying, Wenbin
  • Minomi, Kenjirou
  • Harborth, Jens
  • Takahashi, Hirokazu
  • Terada, Erika
  • Zhang, Jun
  • Ahmadian, Mohammad

Abstract

This invention provides compounds, compositions and methods for modulating the expression of human GST-pi using RNA interference. The RNA interference molecules can be used in methods for preventing or treating diseases such as malignant tumor. Provided are a range of siRNA structures, having one or more of nucleotides being modified or chemically-modified. Advantageous structures include siRNAs with 2'-deoxy nucleotides located in the seed region, as well as other nucleotide modifications

IPC Classes  ?

  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
  • A61P 35/00 - Antineoplastic agents
  • C12N 15/54 - Transferases (2)

33.

POLYMER-BASED HYDROTROPES FOR HYDROPHOBIC DRUG DELIVERY

      
Document Number 02943733
Status In Force
Filing Date 2014-09-01
Open to Public Date 2015-10-15
Grant Date 2022-03-01
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ying, Wenbin
  • Tsang, Kwok Yin
  • Bai, Hao
  • Yin, Haiqing
  • Liu, Jihua
  • Wang, Li

Abstract

The invention disclosed herein relates to a polymer conjugate characterized in that the backbone of the polymer is an anionic polymer and hydrophobic moieties are covalently attached to the backbone of the polymer, a polymer micelle derived from the polymer conjugate, a composition comprising the polymer micelle, and a method for treating a disease or condition using thereof.

IPC Classes  ?

  • A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
  • A61K 9/127 - Liposomes
  • B01J 13/08 - Simple coacervation, i.e. addition of highly hydrophilic material

34.

A TARGETING MOLECULE AND A USE THEREOF

      
Document Number 02944417
Status Pending
Filing Date 2015-04-01
Open to Public Date 2015-10-08
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Minomi, Kenjiro
  • Takahashi, Hirokazu
  • Terada, Erika
  • Niitsu, Yoshiro

Abstract

Provided are: a targeting molecule targeting a target cell which is selected from the group consisting of a stellate cell, a myofibroblast, a cancer-associated fibroblast, a tumor cell and a cell expressing STRA6, said targeting molecule being selected from the group consisting of (1) a peptide containing an amino acid sequence in the cell-binding region of RBP, (2) a variant peptide of the aforesaid peptide (1), said variant peptide having a comparable targeting ability to peptide (1), and (3) a peptide mimetic having a comparable targeting ability to peptide (1) or peptide (2); a targeting agent, a carrier, a complex and a medicinal composition each comprising the targeting molecule; a method for treating, examining, diagnosing or monitoring a disease related to the aforesaid target cell; a method for labeling, detecting or imaging the target cell, etc.

IPC Classes  ?

  • C07K 14/47 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans from vertebrates from mammals
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 49/00 - Preparations for testing in vivo
  • A61P 35/00 - Antineoplastic agents
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • C12N 15/09 - Recombinant DNA-technology

35.

INFRARED-RAY REFLECTIVE FILM

      
Document Number 02908705
Status In Force
Filing Date 2014-03-19
Open to Public Date 2014-10-16
Grant Date 2018-09-04
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Fujisawa, Junichi
  • Ohmori, Yutaka
  • Watanabe, Masahiko

Abstract

An infrared-ray reflective film (100) of the present invention is configured by disposing an infrared reflective layer (20) and a transparent protective layer (30) on a transparent film backing (10) in this order. The infrared reflective layer (20) comprises: a first metal oxide layer (21); a metal layer (25) made of a silver alloy containing silver in an amount of 96 to 99.9 weight%; and a second metal oxide layer (22), which are arranged in this order from the side of the transparent film backing (10), wherein each of the first metal oxide layer (21) and the second metal oxide layer (22) is in direct contact with the metal layer (25). There is no metal layer between the transparent film backing (10) and the infrared reflective layer (20) and between the infrared reflective layer (20) and the transparent protective layer (30). Preferably, the infrared-ray reflective film of the present invention has a visible ray transmittance of 65% or more, a shading coefficient of less than 0.60, and a corrected emissivity as measured from the side of the transparent protective layer of 0.20 or less.

IPC Classes  ?

  • B32B 9/00 - Layered products essentially comprising a particular substance not covered by groups

36.

COMPOSITION FOR ENHANCING TRANSDERMAL ABSORPTION OF DRUG AND PATCH PREPARATION

      
Document Number 02845165
Status In Force
Filing Date 2014-03-07
Open to Public Date 2014-09-11
Grant Date 2021-02-16
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Mukobata, Tsuyoshi
  • Okazaki, Arimichi
  • Hanatani, Akinori
  • Sakamoto, Sachiko

Abstract

The present invention relates to a composition for enhancing transdermal absorption of a drug, containing a polyvalent alcohol having 3 to 8 carbon atoms, an organic acid having 2 to 20 carbon atoms, and a higher alcohol having 12 to 20 carbon atoms, and a patch preparation containing a support and a drug-containing adhesive layer containing the composition on one surface of the support.

IPC Classes  ?

  • A61K 47/12 - Carboxylic acids; Salts or anhydrides thereof
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

37.

INFRARED REFLECTIVE FILM

      
Document Number 02899694
Status In Force
Filing Date 2014-01-30
Open to Public Date 2014-08-07
Grant Date 2017-03-21
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Watanabe, Masahiko
  • Ohmori, Yutaka

Abstract

Disclosed is an infrared reflective film (100) configured by disposing an infrared ray reflective layer (20) and a transparent protective layer (30) on a transparent film backing (10) in this order. The infrared ray reflective layer (20) comprises: a first metal oxide layer (21); a metal layer (25) comprising a primary component consisting of silver; and a second metal oxide layer (22) comprised of a composite metal oxide containing zinc oxide and tin oxide, which are arranged in this order from the side of the transparent film backing (10). The transparent protective layer (30) lies in direct contact with the second metal oxide layer (22). The transparent protective layer (30) has a thickness of 30 nm to 150 nm, and is preferably an organic layer having a cross-linked structure derived from an ester compound having an acidic group and a polymerizable functional group in the same molecule. Preferably, an amount of the ester compound-derived structure contained in the transparent protective layer (30) is 1 to 40 weight%.

IPC Classes  ?

  • B32B 9/00 - Layered products essentially comprising a particular substance not covered by groups
  • B32B 27/00 - Layered products essentially comprising synthetic resin
  • E04B 1/76 - Heat, sound or noise insulation, absorption, or reflection; Other building methods affording favourable thermal or acoustical conditions, e.g. accumulating of heat within walls specifically with respect to heat only

38.

APOPTOSIS-INDUCING AGENT COMPRISING SUPPRESSORS OF GST-.PI. AND AKT

      
Document Number 02895690
Status In Force
Filing Date 2013-12-20
Open to Public Date 2014-06-26
Grant Date 2021-08-10
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Nishita, Hiroki
  • Tanaka, Hiroyuki

Abstract

The purpose of the present invention is to provide a composition for effectively inducing apoptosis and/or proliferation inhibition in a cell, and a method using the same. An agent for inducing apoptosis that comprises as active ingredients a drug inhibiting GST-p and a drug inhibiting Akt; a medicinal composition comprising the same; a method for treating a disease caused by abnormality in apoptosis using the same, etc.

IPC Classes  ?

  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
  • A61P 35/00 - Antineoplastic agents
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

39.

TISSUE REGENERATION PROMOTING AGENT

      
Document Number 02895483
Status Pending
Filing Date 2013-12-20
Open to Public Date 2014-06-26
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Yoneda, Akihiro

Abstract

The purpose of the present invention is to provide a novel tissue regeneration accelerator and tissue regeneration method. The present invention relates to: a composition for accelerating tissue regeneration, accelerating cell differentiation and/or accelerating cell multiplication comprising a component selected from the group consisting of activated stellate cells, the decomposition product of activated stellate cells, MMP14, collagen that has been treated with MMP14, and the secretion product of activated stellate cells; a composition for suppressing cell multiplication comprising MMP14 suppressing material; and a cell cultivation substrate comprising collagen that has been treated with MMP14.

IPC Classes  ?

  • A61K 35/407 - Liver; Hepatocytes
  • A61K 35/12 - Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 38/17 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans
  • A61K 38/43 - Enzymes; Proenzymes; Derivatives thereof
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • C12M 1/00 - Apparatus for enzymology or microbiology

40.

PATCH PREPARATION CONTAINING AMINE OXIDE

      
Document Number 02828588
Status In Force
Filing Date 2013-09-27
Open to Public Date 2014-03-28
Grant Date 2020-10-27
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Nishimura, Masato
  • Inoue, Yoshitaka
  • Ito, Yoshiaki

Abstract

The present invention provides a patch preparation containing a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a drug, amine oxide, a low-polar liquid component based on an organic compound having an angle of 0 - 19° as calculated by the formula (I): angle (°)=arctan (inorganic value/organic value) × (180/.pi.) and using an inorganic value and an organic value on an organic conceptual diagram, and an adhesive base, and the adhesive layer has an amine oxide content of 0.1 - 5 wt% and a low-polar liquid component content of 30 - 50 wt%.

IPC Classes  ?

  • A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

41.

SUPPORT BODY FOR TRANSDERMAL PATCH OR TRANSDERMAL PREPARATION, AND TRANSDERMAL PATCH AND TRANSDERMAL PREPARATION USING SAME

      
Document Number 02883123
Status In Force
Filing Date 2013-09-20
Open to Public Date 2014-03-27
Grant Date 2020-06-02
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Urushihara, Naoko
  • Ameyama, Satoshi

Abstract

The present invention provides a transdermal patch or a transdermal preparation in which anchoring to a support body of an adhesive layer is improved without negatively affecting adhesive properties such as adherence, adhesiveness, and cohesiveness. The support body of the present invention is a support body for a transdermal patch or transdermal preparation provided with a plastic film-containing substrate, and an undercoat agent layer layered on the substrate, wherein the undercoat agent layer contains porous inorganic particles having a mean particle size of 1 µm to 15 µm. This transdermal patch or transdermal preparation is provided with the support body and an adhesive layer arranged so as to be adjacent to the undercoat agent layer on one surface of the support body.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/02 - Inorganic compounds
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

42.

PACKAGING MATERIAL AND PACKAGE STRUCTURE USING THE SAME

      
Document Number 02827568
Status In Force
Filing Date 2013-09-17
Open to Public Date 2014-03-21
Grant Date 2020-07-21
Owner
  • TOYO SEIKAN GROUP HOLDINGS, LTD. (Japan)
  • NITTO DENKO CORPORATION (Japan)
Inventor
  • Ishizaki, Yoichi
  • Ohta, Yoshihiro
  • Hanatani, Akinori
  • Sakamoto, Sachiko
  • Mukobata, Tsuyoshi
  • Iwao, Yoshihiro

Abstract

An object of the present invention is to provide a packaging material that is capable of long term storage by preventing adsorption or transfer of an easily oxidizable component and an oily component in an adhesive of a patch to the packaging material, and also preventing discoloration and decrease in drug effect due to oxidization. The present invention provides the packaging material for a patch including: an inner layer made of polyethylene terephthalate having heat sealing properties; an oxygen-absorbing layer that includes an oxygen-absorbing resin having an unsaturated alicyclic structure as an oxygen-absorbing part; and an oxygen barrier layer made of aluminum foil as an outer layer.

IPC Classes  ?

  • B65D 65/40 - Applications of laminates for particular packaging purposes
  • A61K 9/70 - Web, sheet or filament bases
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • B32B 15/09 - Layered products essentially comprising metal comprising metal as the main or only constituent of a layer, next to another layer of a specific substance of synthetic resin comprising polyesters
  • B32B 33/00 - Layered products characterised by particular properties or particular surface features, e.g. particular surface coatings; Layered products designed for particular purposes not covered by another single class

43.

LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS

      
Document Number 02876148
Status In Force
Filing Date 2013-06-07
Open to Public Date 2013-12-12
Grant Date 2021-01-12
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Payne, Joseph E.
  • Gaudette, John A.
  • Hou, Zheng
  • Ahmadian, Mohammad
  • Yu, Lei
  • Knopov, Victor
  • Akopian, Violetta
  • Karmali, Priya
  • Witte, Richard P.
  • Safarzadeh, Neda
  • Ying, Wenbin
  • Zhang, Jun

Abstract

The description is directed to ionizable lipid compounds of formula I or pharmaceutically acceptable salts thereof, which are useful for enhancing the delivery of therapeutic agents in liposomes to cells, tissues, and organisms. Compositions, pharmaceutical formulations, drug carriers and methods of using the compounds of formula I are also provided. (see formula I)

IPC Classes  ?

  • C07C 271/16 - Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
  • A61K 47/16 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen
  • A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
  • A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
  • C07C 235/08 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
  • C07C 237/08 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
  • C07C 317/44 - Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
  • C07C 321/14 - Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
  • C07C 333/04 - Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
  • C07D 207/16 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
  • C07D 333/40 - Thiophene-2-carboxylic acid

44.

VACCINE COMPOSITION HAVING AN ANTIGEN AND A TOLL-LIKE RECEPTOR 4 AGONIST

      
Document Number 02811762
Status In Force
Filing Date 2013-04-04
Open to Public Date 2013-10-04
Grant Date 2021-09-14
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Fukasaka, Masahiro
  • Okazaki, Arimichi
  • Asari, Daisuke
  • Hori, Mitsuhiko
  • Akira, Shizuo
  • Takeuchi, Osamu

Abstract

An intraorally administrable vaccine composition useful to be a preventive or therapeutic agent for infectious diseases, and effectively induces a systemic immune response or a mucosal immune response is provided. A vaccine composition for administration to the oral cavity of a human or an animal, the vaccine composition containing at least one antigen derived from an infectious disease, and at least one selected from the group consisting of a toll-like receptor 4 (TLR4) agonist, a toll-like receptor 2/6 (TLR2/6) agonist, and cyclic dinucleotide, or a derivative or salt thereof.

IPC Classes  ?

  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
  • A61K 39/145 - Orthomyxoviridae, e.g. influenza virus
  • A61K 39/295 - Polyvalent viral antigens; Mixtures of viral and bacterial antigens
  • A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses
  • A61P 37/04 - Immunostimulants

45.

METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY

      
Document Number 02853689
Status In Force
Filing Date 2012-11-02
Open to Public Date 2013-06-27
Grant Date 2020-06-30
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Knopov, Victor
  • Witte, Richard P.
  • Karmali, Priya
  • Lee, Robin
  • Webb, David
  • Akopian, Violetta

Abstract

What is described is a method for preparing a liposome that efficiently encapsulates a negatively charged therapeutic polymer, e.g., siRNA. The process involves preparing a lipid mixture comprising a cationic lipid in a water miscible organic solvent such as ethanol, and injecting this solution to the polymer dissolved in water to a final concentration of 35% ethanol in water to produce nanoparticles having a mean size of 50 to 150 nm and a final charge ratio of drug:lipid is 1 :2.5.

IPC Classes  ?

  • A61K 9/127 - Liposomes
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

46.

AGENT FOR TREATING FIBROSIS OF THE INTESTINE

      
Document Number 02856016
Status In Force
Filing Date 2012-11-16
Open to Public Date 2013-05-23
Grant Date 2020-09-22
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ayabe, Tokiyoshi
  • Nakamura, Kiminori
  • Minomi, Kenjiro
  • Tanaka, Yasunobu

Abstract

The present invention pertains to a material delivery carrier for extracellular matrix-producing cells in the intestines, the carrier comprising a retinoid as a targeting agent, as well as to an intestinal fibrosis treatment agent using the carrier.

IPC Classes  ?

  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • A61K 45/08 - Mixtures of an active ingredient and an auxiliary substance neither being chemically characterised, e.g. antihistaminicum and surface active substance
  • A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
  • C12N 15/09 - Recombinant DNA-technology
  • G01N 33/15 - Medicinal preparations
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • A61K 9/127 - Liposomes
  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides

47.

SINGLE USE SYSTEM FOR STERILELY PRODUCING LIPID-NUCLEIC ACID PARTICLES

      
Document Number 02853685
Status In Force
Filing Date 2012-11-02
Open to Public Date 2013-05-10
Grant Date 2019-09-03
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Knopov, Victor
  • Witte, Richard P.
  • Karmali, Priya
  • Lee, Robin
  • Webb, David

Abstract

Sterile preparation of a lipid-drug nanoparticle includes transferring an aqueous drug solution from a first holding unit to a mixing unit and adding a solution of lipids in a water-miscible organic solvent from a second holding unit to the aqueous drug solution, using injection means so as to form a gradient of the organic solvent concentration in the solution in the mixing unit. The resulting lipid-drug mixture is diluted with an aqueous buffer to form a liposome suspension, which is then concentrated using a transflow filter to remove the organic solvent. The concentrated liposome suspension is collected in a single use bed for subsequent aseptic dispensing. Apparatus used to carry out the process contains components which are sterilized and disposable so as to be adapted for single batch usage.

IPC Classes  ?

  • A61K 9/127 - Liposomes
  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • B01J 13/02 - Making microcapsules or microballoons
  • B01J 13/04 - Making microcapsules or microballoons by physical processes, e.g. drying, spraying

48.

ADHESIVE PATCH AND ADHESIVE PREPARATION

      
Document Number 02751350
Status In Force
Filing Date 2011-09-01
Open to Public Date 2013-03-01
Grant Date 2019-01-15
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Harima, Jun
  • Konno, Masakatsu
  • Hashino, Ryo
  • Numata, Akira

Abstract

The present invention provides an adhesive patch comprising a support, an adhesive layer on at least one surface of the support, and a release liner on a surface of the adhesive layer opposite from the support, wherein (a) the lateral end of the adhesive layer is exposed, (b) in at least one lateral end, the lateral end of the adhesive layer is located toward the central part side of the adhesive patch from the lateral end of the support, and (c) when placed horizontally with the release liner facing down, a distance A between the upper end of the support and the lower end of the release liner at said lateral end of the adhesive patch is greater than a thickness B of the central part of the adhesive patch.

IPC Classes  ?

  • C09J 7/20 - Adhesives in the form of films or foils characterised by their carriers
  • C09J 7/30 - Adhesives in the form of films or foils characterised by the adhesive composition
  • C09J 7/40 - Adhesives in the form of films or foils characterised by release liners
  • A61K 9/70 - Web, sheet or filament bases
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

49.

PATCH PREPARATION

      
Document Number 02783106
Status In Force
Filing Date 2012-07-11
Open to Public Date 2013-01-20
Grant Date 2019-01-08
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Mitsushima, Masahiro
  • Kuroda, Hidetoshi
  • Saeki, Yuji
  • Takita, Tomohito

Abstract

The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability and in anchoring property of its drug-containing pressure-sensitive adhesive layer, and has a preferred patch feeling. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 µm to 16 µm; and the pressure-sensitive adhesive layer is laminated on the polyester nonwoven fabric layer.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

50.

APOPTOSIS-INDUCING AGENT

      
Document Number 02841203
Status In Force
Filing Date 2011-06-21
Open to Public Date 2012-12-27
Grant Date 2019-01-22
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Nishita, Hiroki

Abstract

This invention relates to: a novel use of GST-n and GST-n suppressing agents; an apoptosis-inducing agent containing as active components a drug that suppresses GST-n and a drug that suppresses autophagy; a medical composition containing said agent; and a method using said medical composition for treating diseases associated with abnormal apoptosis.

IPC Classes  ?

  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
  • A61P 35/00 - Antineoplastic agents
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups

51.

COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY

      
Document Number 03094645
Status In Force
Filing Date 2012-06-08
Open to Public Date 2012-12-13
Grant Date 2023-01-03
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Payne, Joseph E.
  • Hou, Zheng
  • Gaudette, John A.
  • Sridhar, C. Nagarajan
  • Knopov, Victor
  • Witte, Richard P.
  • Ahmadian, Mohammad
  • Perelman, Loren A.
  • Tanaka, Yasunobu
  • Akopian, Violetta
  • Karmali, Priya

Abstract

Compounds of the structure (retinoid)m-linker-(retinoid)n wherein m and n are independently 0, 1, 2 or 3; and wherein the linker comprises a polyethylene glycol (PEG), PEG- like molecule, Glu, G1y3 and/or GluNH are useful for facilitating drug delivery to a target cell. The retinoid may have a specific receptor or activation/binding site on the target cell.

IPC Classes  ?

  • C07C 237/22 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

52.

RETINOID-LIPOSOMES FOR ENHANCING MODULATION OF HSP47 EXPRESSION

      
Document Number 02836925
Status In Force
Filing Date 2012-06-08
Open to Public Date 2012-12-13
Grant Date 2021-11-16
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Akopian, Violetta
  • Minomi, Kenjiro
  • Niitsu, Yoshiro
  • Payne, Joseph E.
  • Knopov, Victor
  • Witte, Richard P.
  • Ahmadian, Mohammad
  • Perelman, Loren A.
  • Tanaka, Yasunobu
  • Feinstein, Elena
  • Avkin-Nahum, Sharon
  • Kalinski, Hagar
  • Mett, Igor
  • Ying, Wenbin
  • Liu, Yun

Abstract

What is described are pharmaceutical compositions comprising a double-stranded nucleic acid molecule comprising a sense strand and an antisense strand wherein the sense and antisense strands are selected from the oligonucleotides described as SERPINH1_2 (SEQ ID NOS: 60 and 127), SERPTNHl_45a (SEQ ID NOS: 98 and 165), and SERPTNH1_51 (SEQ ID NOS: 101 and 168), and drug carrier comprising a mixture of a retinoid and a lipid vesicle, and methods of using these pharmaceutical compositions to treat a disease associated with hsp47 espresssion, including fibrosis.

IPC Classes  ?

  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
  • A61K 38/17 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans
  • C12N 15/11 - DNA or RNA fragments; Modified forms thereof

53.

COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY

      
Document Number 02837101
Status In Force
Filing Date 2012-06-08
Open to Public Date 2012-12-13
Grant Date 2020-12-15
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Karmali, Priya
  • Sridhar, C. Nagarajan
  • Niitsu, Yoshiro
  • Hou, Zheng
  • Gaudette, John A.
  • Knopov, Victor
  • Ahmadian, Mohammad
  • Tanaka, Yasunobu
  • Akopian, Violetta
  • Payne, Joseph E.
  • Witte, Richard P.
  • Perelman, Loren A.

Abstract

Here described are compounds of formula I: wherein R1 and R2 is independently selected from a group consisting of C10 to C18 alkyl, C12 to C18 alkenyl, and oleyl group; wherein R3 and R4 are independently selected from a group consisting of C1 to C6 alkyl, and C2 to C6 alkanol; wherein X is selected from a group consisting of -CH2-, -S-, and -O- or absent; wherein Y is selected from -(CH2)n, -S(CH2)n, -O(CH2)n-, thiophene, -SO2(CH2)n-, and ester, wherein n = 1 -4; wherein a = 1 -4; wherein b=l -4; wherein c=l-4; and wherein Z is a counterion; and compounds consisting of the structure (targeting molecule)m-linker-(targeting molecule)n, wherein the targeting molecule is a retinoid or a fat soluble vitamin having a specific receptor on the target cell; wherein m and n are independently 0, 1, 2 or 3; and wherein the linker comprises a polyethylene glycol (PEG) or PEG-like molecule, as well as compositions and pharmaceutical formulations including one or both of these compounds which are useful for the delivery of therapeutic agents; and methods of using these compositions and pharmaceutical formulations.

IPC Classes  ?

  • C07C 237/08 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
  • A61K 47/50 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
  • A61K 9/127 - Liposomes
  • A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
  • A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
  • A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
  • C07C 323/60 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
  • C07C 333/04 - Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms

54.

PATCH PREPARATION

      
Document Number 02825798
Status In Force
Filing Date 2012-02-01
Open to Public Date 2012-08-09
Grant Date 2018-12-04
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Okada, Yasuaki
  • Okada, Katsuhiro
  • Nishimura, Masato
  • Kawaharada, Yuji

Abstract

The problem of the present invention is to provide a patch preparation containing a drug (excluding 2-(4-ethyl-1- piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10- hexahydrocycloocta[b]pyridine and a physiologically acceptable acid addition salt thereof), which is superior in both the skin permeability of a drug, and adhesiveness in the presence of water. A patch preparation containing a support and an adhesive layer on one surface of the support, wherein the adhesive layer contains a drug excluding 2-(4-ethyl-1-piperazinyl)-4-(4- fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine and a physiologically acceptable acid addition salt thereof, an acrylic polymer, lactic acid and magnesium aluminometasilicate.

IPC Classes  ?

  • A61K 47/12 - Carboxylic acids; Salts or anhydrides thereof
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
  • A61K 47/04 - Non-metals; Compounds thereof
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

55.

A PATCH AND PATCH PREPARATION COMPRISING A SUPPORT AND AN ADHESIVE LAYER

      
Document Number 02826218
Status In Force
Filing Date 2012-02-01
Open to Public Date 2012-08-09
Grant Date 2019-06-25
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Nishimura, Masato
  • Iwao, Yoshihiro
  • Okada, Katsuhiro
  • Matsuoka, Kensuke

Abstract

The problem of the present invention is to provide a patch and a patch preparation having an adhesive layer with a high adhesive force, wherein the hydrophobic adhesive layer does not bleed even when an organic fluid component having high polarity is contained. A patch containing a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber having a viscosity average molecular weight of 500,000- 1,600,000, an organic fluid component having high polarity, a tackifier, and magnesium aluminometasilicate. In the patch preparation, the above-mentioned adhesive layer further contains a drug.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/02 - Inorganic compounds
  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

56.

A PATCH AND PATCH PREPARATION COMPRISING A SUPPORT AND ADHESIVE LAYER

      
Document Number 02826362
Status In Force
Filing Date 2012-02-01
Open to Public Date 2012-08-09
Grant Date 2019-07-09
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Nishimura, Masato
  • Iwao, Yoshihiro
  • Okada, Katsuhiro
  • Matsuoka, Kensuke

Abstract

The problem of the present invention is to provide a patch and a patch preparation having an adhesive layer with a high adhesive force, wherein the hydrophobic adhesive layer does not bleed even when an organic fluid component having high polarity is contained. A patch containing a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a synthetic rubber having a viscosity average molecular weight of 1,700,000 - 6,500,000, an organic fluid component having high polarity, a tackifier, and magnesium aluminometasilicate. In the patch preparation, the above-mentioned adhesive layer further contains a drug.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/02 - Inorganic compounds
  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

57.

DEVICES AND METHODS FOR PHOTOPLETHYSMOGRAPHIC MEASUREMENTS

      
Document Number 02815643
Status In Force
Filing Date 2012-01-05
Open to Public Date 2012-07-26
Grant Date 2019-01-15
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Thaveeprungsriporn, Visit
  • Kassim, Md. Irwan Bin Md.
  • Naing, Nyan Myo
  • Samsudin, Mohamad Sulhede Bin

Abstract

An optical measurement device and method of use provides non-invasive physiological measurements from a predetermined location on a body part of a user. The optical measurement device provides an illumination and detection assembly configured to generate and detect light of a predetermined wavelength range in the form of a photoplethysmography (PPG) signal, as well as a pressure detection assembly configured to detect an amount of pressure applied to the measurement device by the user being measured. A feedback unit, such as a portable display device, can be coupled to the measurement device to provide the user with real-time feedback of the detected PPG signal and level of applied pressure so that the user may adjust the amount of applied pressure to improve the quality of the detected PPG signal.

IPC Classes  ?

  • A61B 5/0295 - Measuring blood flow using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
  • A61B 5/02 - Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
  • G01N 21/25 - Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands

58.

COMPOSITION FOR REGENERATING NORMAL TISSUE FROM FIBROTIC TISSUE

      
Document Number 02807033
Status In Force
Filing Date 2011-08-05
Open to Public Date 2012-02-09
Grant Date 2021-01-12
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Yoneda, Akihiro
  • Ishiwatari, Hirotoshi

Abstract

The invention pertains to a pharmaceutical composition and method for regenerating normal tissue from fibrotic tissue that comprise a collagen-reducing substance. The invention makes possible the therapeutic regeneration of normal tissue from fibrotic tissue.

IPC Classes  ?

59.

AGENT FOR TREATING RENAL FIBROSIS

      
Document Number 02802414
Status In Force
Filing Date 2011-06-17
Open to Public Date 2011-12-22
Grant Date 2018-01-09
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Kajiwara, Keiko
  • Tanaka, Yasunobu
  • Miyazaki, Miyono

Abstract

The present invention relates to a substance delivery carrier for extracellular matrix-producing cells in the kidney, the carrier including a retinoid as a targeting agent, an agent for treating renal fibrosis utilizing the carrier, a process for producing them, a production kit, a method for treating renal fibrosis using the agent for treating renal fibrosis, etc.

IPC Classes  ?

  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • A61K 9/127 - Liposomes
  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
  • A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups

60.

LAMINATE STRUCTURE WITH EMBEDDED CAVITIES AND RELATED METHOD OF MANUFACTURE

      
Document Number 02795864
Status In Force
Filing Date 2011-04-06
Open to Public Date 2011-10-13
Grant Date 2018-05-01
Owner NITTO DENKO CORPORATION (Japan)
Inventor Rinko, Kari

Abstract

An integrated laminate structure (202, 302, 402, 502, 602, 702a, 702b, 801, 902, 1002, 1216) adapted for application in the context of solar technology, wafer technology, cooling channels, greenhouse illumination, window illumination, street lighting, traffic lighting, traffic reflectors or security films, comprising a first carrier element (206, 304, 406, 505, 506, 606, 704, 804, 1006, 1204) such as a piece of plastic or glass, optionally comprising optically substantially transparent material enabling light transmission therethrough, a second carrier element (204, 306, 404, 504, 505, 604, 702, 802, 1004, 1206) provided with at least one surface relief pattern (308, 802a, 1206b) comprising a number of surface relief forms (208, 308a, 308b, 408, 412, 508, 510, 608, 610, 708) and having at least one predetermined optical function (708a, 710, 712) relative to incident light, said second carrier element optionally comprising optically substantially transparent material enabling light transmission therethrough, the first and second carrier elements being laminated together such that the at least one surface relief pattern has been embedded within the established laminate structure and a number of related cavities (210, 308b, 408, 410, 412, 508, 510, 608, 610, 709) have been formed at the interface of said first and second carrier elements. An applicable method of manufacture is presented.

IPC Classes  ?

  • B32B 3/26 - Layered products essentially comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar form; Layered products essentially having particular features of form characterised by a layer with cavities or internal voids
  • B32B 37/00 - Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
  • F21V 5/00 - Refractors for light sources
  • G09F 13/04 - Signs, boards, or panels, illuminated from behind the insignia

61.

PATCH PREPARATION AND PRODUCTION METHOD THEREOF

      
Document Number 02735634
Status In Force
Filing Date 2011-03-29
Open to Public Date 2011-09-30
Grant Date 2019-01-08
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Sakamoto, Sachiko
  • Hanatani, Akinori
  • Okazaki, Arimichi
  • Akemi, Hitoshi
  • Iwao, Yoshihiro
  • Matsuoka, Kensuke

Abstract

Provided is a patch preparation containing: a support; and an adhesive layer containing a drug on the surface of the support, wherein a crystal of the drug is formed in the adhesive layer immediately after application of a physical stimulation to the adhesive layer, while a crystal of the drug is formed during preservation after the physical stimulation. According to the present invention, a patch preparation which does not require increase in the area and thickness of an adhesive layer, achieves sufficiently high skin permeation amount of a drug, shows good adhesiveness to the skin and permits a long-term adhesion, and a production method thereof can be provided.

IPC Classes  ?

62.

ADHESIVE SKIN PATCH

      
Document Number 02791196
Status In Force
Filing Date 2011-02-23
Open to Public Date 2011-09-01
Grant Date 2017-02-28
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Iwao, Yoshihiro
  • Matsuoka, Kensuke
  • Aoyagi, Kazuhiro

Abstract

Disclosed is an adhesive skin patch containing medication other than bisoprolol. Specifically disclosed is an adhesive skin patch which is suppressed in the occurrence of oozing or squeezing-out of the components of the adhesive layer of the adhesive skin patch from the exposed section of the adhesive layer and in the reduction of a medication content due to the oozing of the medication from the adhesive layer, which occur while the adhesive skin patch is stored. Each of a support, a peeling liner, and the adhesive layer and the whole of the adhesive skin patch have a rectangular planar shape, projecting sections being respectively provided on the support-side surface at the corners of the adhesive skin patch. Moreover, it is possible to provide the center section and the circumferential section in the adhesive skin patch and to provide projecting sections at the corners of the rectangular shape of the center section. Furthermore, it is possible to provide, between two or more adjacent projecting sections, raised connecting sections where the adhesive skin patch is thinner than in the projecting sections. If providing a back split section in the peeling liner, the back split section is made to avoid passing through the projecting sections.

IPC Classes  ?

63.

MODULATION OF HSP47 EXPRESSION

      
Document Number 02781896
Status In Force
Filing Date 2010-12-08
Open to Public Date 2011-06-16
Grant Date 2021-03-30
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Jin, Xiaomei
  • Yu, Lei
  • Takahashi, Hirokazu
  • Tanaka, Yasunobu
  • Niitsu, Yoshiro
  • Feinstein, Elena
  • Avkin-Nachum, Sharon
  • Kalinski, Hagar
  • Mett, Igor
  • Erlich, Shai
  • Squiers, Elizabeth C.
  • Chen, Ning

Abstract

Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA) or short hairpin RNA (shRNA)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47. The composition and methods disclosed herein may also be used in treating conditions and disorders associated with hsp47 such as liver fibrosis, pulmonary fibrosis, peritoneal fibrosis and kidney fibrosis.

IPC Classes  ?

  • C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
  • A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
  • C07H 21/00 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
  • C07K 14/47 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans from vertebrates from mammals
  • C12N 15/12 - Genes encoding animal proteins

64.

PATCH AND PATCH PREPARATION

      
Document Number 02721866
Status In Force
Filing Date 2010-11-19
Open to Public Date 2011-05-20
Grant Date 2018-01-02
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ishikura, Jun
  • Funayama, Raito
  • Tachikawa, Yu
  • Sekiya, Junichi
  • Kasahara, Tsuyoshi
  • Hashino, Ryo
  • Ameyama, Satoshi
  • Kuroda, Hidetoshi

Abstract

The patch according to an embodiment of the present invention includes: a support; and a pressure-sensitive adhesive layer on at least one surface of the support, wherein: the pressure-sensitive adhesive layer contains an acrylic copolymer obtained by copolymerizing monomer components containing (a) at least one kind of a monomer of a (meth)acrylic acid alkyl ester and (b) at least one kind of a monomer of an N- hydroxyalkyl(meth)acrylamide; a content of the (meth)acrylic acid alkyl ester monomer (a) with respect to a total amount of the monomer components is 50 wt% to 90 wt% and a content of the N--hydroxyalkyl(meth)acrylamide monomer (b) with respect to the total amount is 1 wt% to 20 wt%; and the monomer components are substantially free of a monomer having a carboxyl group.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

65.

MEDICAL PRESSURE-SENSITIVE ADHESIVE COMPOSITION

      
Document Number 02721887
Status In Force
Filing Date 2010-11-19
Open to Public Date 2011-05-20
Grant Date 2018-10-09
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ishikura, Jun
  • Funayama, Raito
  • Tachikawa, Yu
  • Sekiya, Junichi
  • Kasahara, Tsuyoshi
  • Okamoto, Masayuki
  • Niwa, Masahito

Abstract

There is provided a medical pressure-sensitive adhesive composition including an acrylic copolymer obtained by copolymerizing monomer components containing (a) at least one kind of a monomer of a (meth)acrylic acid alkyl ester and (b) at least one kind of a monomer of an N-hydroxyalkyl(meth)acrylamide, wherein: a content of the (meth)acrylic acid alkyl ester monomer (a) with respect to a total amount of the monomer components is 50 weight% to 99.9 weight% and a content of the N-hydroxyalkyl(meth)acrylamide monomer (b) with respect to the total amount is 0.1 weight% to 20 weight%; and the monomer components are substantially free of a monomer having a carboxyl group. The medical pressure-sensitive adhesive composition of the present invention is particularly suitable for applications such as medical patches and patch preparations.

IPC Classes  ?

  • C09J 133/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
  • C09J 133/24 - Homopolymers or copolymers of amides or imides
  • A61K 9/70 - Web, sheet or filament bases
  • A61L 15/58 - Adhesives

66.

EXTRUSION MATERIAL SUPPLY DEVICE AND OPTICAL TRANSMISSION BODY MANUFACTURING METHOD USING THE SAME

      
Document Number 02755374
Status In Force
Filing Date 2010-01-26
Open to Public Date 2010-09-30
Grant Date 2015-09-15
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Okamoto, Tazuru
  • Yoshida, Hirotsugu
  • Koike, Yasuhiro

Abstract

The invention provides an extrusion material supply device suitable for use in melt extrusion molding, and a method for manufacturing an optical transmission body, in which a deterioration of an optical signal transmission loss is extremely small, and productivity intrinsic to an extrusion molding method is provided in combination. An extrusion material supply device 1 includes: a vertical hopper 2, which has a cooling unit 3 and a heat melting unit 4 continuous with a lower portion thereof, and houses a material rod R; cooling means 5 for cooling the cooling unit 3; an electric heater 6 that heats the heat melting unit 4; and gas pressurizing means 7 for sequentially supplying molten plastics M to a metal die by a gas pressure. The heat melting unit 4 is formed into a cylinder shape in which an inner diameter is larger than an inner diameter of the cooling unit 3 arranged above, and enables the molten plastics M to spread in the heat melting unit 4. A portion between an outer circumference of the material rod R and an outer circumference of the molten plastics M is defined as an annular gas pressurizing surface 7a.

IPC Classes  ?

  • B29C 48/28 - Storing of extruded material, e.g. by winding up or stacking
  • G02B 6/00 - Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings

67.

PATCH AND PATCH PREPARATION

      
Document Number 02692536
Status In Force
Filing Date 2010-02-09
Open to Public Date 2010-08-10
Grant Date 2017-02-07
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Terashi, Sachiko
  • Hanatani, Akinori
  • Akemi, Hitoshi
  • Iwao, Yoshihiro

Abstract

The present invention provides to a patch and a patch preparation having low stretchability, which can be continuously adhered to the skin for a long time without undesirable detachment and marked falling off from the skin due to various factors during adhesion, and specifically provides a low stretchable patch and a patch preparation containing a support and an adhesive layer formed on one surface of the support, wherein a ratio P of the total length W (mm) of curved sections of a planar outer shape of the patch to the total length S (mm) of straight-line sections of the planar outer shape of the patch (W/S) is not more than 1.22, and, when the curved sections are approximated by a circular arc, the radius R (mm) of the circular arc is not less than 0.5 mm.

IPC Classes  ?

68.

PATCH PACKAGE STRUCTURE

      
Document Number 02688761
Status In Force
Filing Date 2009-12-17
Open to Public Date 2010-06-22
Grant Date 2015-10-13
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Okada, Katsuhiro
  • Iwao, Yoshihiro
  • Matsuoka, Kensuke

Abstract

A patch package structure which includes: a package including a first sheet material which is planar and a second sheet material which has been molded, a peripheral area of the first sheet material having been sealed to a peripheral area of the second sheet material to constitute the package, and a patch disposed in the package; in which the patch includes a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner which protects the pressure- sensitive adhesive surface of the pressure-sensitive adhesive layer, the release liner having a weakening line for assisting a removal of the release liner; and in which the second sheet material has specific first protrudent part, second protrudent part, third protrudent part and elevated part in a central area thereof except the peripheral area thereof.

IPC Classes  ?

  • B65D 75/34 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents and having several recesses to accommodate a series of articles or quantities of material
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • B32B 7/12 - Interconnection of layers using interposed adhesives or interposed materials with bonding properties
  • B32B 27/08 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of synthetic resin of a different kind

69.

BLISTER PACKAGE

      
Document Number 02685620
Status In Force
Filing Date 2009-11-16
Open to Public Date 2010-05-17
Grant Date 2016-08-23
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Matsuoka, Kensuke
  • Iwao, Yoshihiro
  • Okada, Katsuhiro

Abstract

Provision of a blister package that cannot be opened easily by infants, but can be opened easily, certainly and safely by a user when in use. A blister package 100 containing a blister 1 and a cover sheet 2, wherein the blister has a groove 3 formed in an outer edge section 1A thereof where the cover sheet is adhered and the groove 3 is free of adhesion of the sheet. The cover sheet is adhered to the outermost circumference la of the outer edge section 1A, the groove 3 is formed on the inward side of the outermost circumference la, and the cover sheet is not adhered to the area on the inward side of the groove 3.

IPC Classes  ?

  • B65D 75/36 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages

70.

AGENT FOR TREATING MYELOFIBROSIS

      
Document Number 02735709
Status In Force
Filing Date 2009-09-04
Open to Public Date 2010-03-11
Grant Date 2017-03-07
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Matsunaga, Takuya

Abstract

Disclosed is a substance delivery carrier for an extracellular-matrix- producing cell in the bone marrow, which comprises a retinoid. Also disclosed is an agent for treating myelofibrosis by utilizing a substance capable of regulating the activity or proliferation of an extracellular-matrix-producing cell in the bone marrow.

IPC Classes  ?

  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • A61K 9/127 - Liposomes
  • A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
  • A61P 7/00 - Drugs for disorders of the blood or the extracellular fluid
  • A61P 19/00 - Drugs for skeletal disorders
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups

71.

ADHESIVE PATCH

      
Document Number 02676757
Status In Force
Filing Date 2009-08-26
Open to Public Date 2010-02-28
Grant Date 2018-02-13
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Harima, Jun
  • Konno, Masakatsu
  • Hashino, Ryo
  • Numata, Akira

Abstract

An adhesive patch containing an adhesive patch main part containing a support and an adhesive layer laminated on the support, wherein the adhesive patch main part comprises a peripheral part, a central part, and an intermediate part between the peripheral part and the central part, the intermediate part of the adhesive patch main part has a thickness greater than that of the central part of the adhesive patch main part, and the central part of the adhesive patch main part has a thickness greater than that of the peripheral part of the adhesive patch main part, and a production method thereof.

IPC Classes  ?

  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61L 15/26 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof

72.

PROCESS FOR PRODUCING ADHESIVE PATCH

      
Document Number 02671887
Status In Force
Filing Date 2009-07-14
Open to Public Date 2010-01-16
Grant Date 2016-04-12
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Hashino, Ryo
  • Konno, Masakatsu
  • Harima, Jun

Abstract

The invention provides a process for producing an adhesive patch, which includes a step of preparing a pressure-sensitive adhesive sheet including a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner disposed on the pressure-sensitive adhesive layer; and a step of punching an adhesive patch including a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner disposed on the pressure- sensitive adhesive layer out of the pressure-sensitive adhesive sheet with a protrudent push cutter blade, in which, at at least an edge part of the protrudent push cutter blade, a cross-sectional shape of the protrudent push cutter blade, which is in a direction perpendicular to the direction in which the protrudent push cutter blade extends, has an angle .alpha. and an angle b, in which the angle .alpha. is larger than the angle b. The angle .alpha. and angle b in the sectional shape have the meanings described in the specification.

IPC Classes  ?

  • B32B 37/12 - Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by using adhesives
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • B32B 38/04 - Punching, slitting or perforating

73.

THERAPEUTIC AGENT FOR FIBROID LUNG

      
Document Number 02718560
Status In Force
Filing Date 2009-03-16
Open to Public Date 2009-09-24
Grant Date 2017-12-19
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Takimoto, Rishu

Abstract

Disclosed are: a substance transfer carrier to an extracellular matrix-producing cell in the lung, which comprises a retinoid; a therapeutic agent for fibroid lung, which utilized the carrier; and a preparation kit of the therapeutic agent.

IPC Classes  ?

  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • A61K 9/127 - Liposomes
  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
  • A61P 11/00 - Drugs for disorders of the respiratory system

74.

PATCH AND ADHESIVE PREPARATION

      
Document Number 02637874
Status In Force
Filing Date 2008-07-16
Open to Public Date 2009-01-20
Grant Date 2014-08-19
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Hashino, Ryo
  • Konno, Masakatsu
  • Harima, Jun

Abstract

The invention relates to a patch including a backing, a pressure-sensitive adhesive layer, and a release liner, the patch at an edge part thereof having such a sectional shape that, when a perpendicular segment is drawn from an edge of the backing at the edge part of the patch to the release liner, at least a part of an edge of the pressure-sensitive adhesive layer at the edge part of the patch is located on the center side of the patch with respect to the segment, and the edge of the pressure- sensitive adhesive layer being exposed. According to the invention, a patch and an adhesive preparation in each of which the pressure-sensitive adhesive is less apt to protrude or flow out from the edges thereof can be provided.

IPC Classes  ?

  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61K 9/70 - Web, sheet or filament bases
  • A61L 15/58 - Adhesives

75.

PATCH PACKAGE STRUCTURE

      
Document Number 02617455
Status In Force
Filing Date 2008-01-09
Open to Public Date 2008-07-11
Grant Date 2011-10-11
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Okada, Katsuhiro
  • Iwao, Yoshihiro
  • Matsuoka, Kensuke

Abstract

The present invention provides a patch package structure, which includes: a package including a first sheet material which is planar and a second sheet material which has been molded, the first and second sheet materials being sealed together in peripheral parts thereof, and a patch disposed in the package, in which the patch contains a backing, a pressure-sensitive adhesive layer laminated on at least one side of the backing, and a release liner which protects a pressure-sensitive adhesive surface of the pressure-sensitive adhesive layer; the second sheet material has been molded so as to have a protrudent part in at least a substantially central area thereof, the protrudent part having a planar outer shape larger than a planar outer shape of the release liner and having at least one recessed part; d is not smaller than T, in which d is the minimum gap distance between the inner surface of the first sheet material and the inner surface of the second sheet material at the recessed part and T is a thickness of the patch; and, at the boundary between the sealed part where the first and second sheet materials are sealed together and an unsealed part, the outer surface of the second sheet material rises at an obtuse angle.

IPC Classes  ?

  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • B65D 75/32 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
  • B65D 85/00 - Containers, packaging elements or packages, specially adapted for particular articles or materials

76.

MANUFACTURING APPARATUS OF TRANSDERMAL ABSORPTION PREPARATION

      
Document Number 02613558
Status In Force
Filing Date 2007-12-05
Open to Public Date 2008-06-20
Grant Date 2014-09-23
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Satoda, Shiro
  • Kikuchi, Shunetsu
  • Ninomiya, Kazuhisa
  • Okada, Katsuhiro
  • Akemi, Hitoshi

Abstract

A manufacturing apparatus of a transdermal absorption preparation, comprising an adhesive sheet supplying part A to feed out a band-like first adhesive sheet 3 into a runway, wherein the adhesive sheet has at least an adhesive layer comprising an adhesive and a liquid component compatible with the adhesive, a drug liquid application part B to apply a given amount of a drug liquid to an adhesive face 2b, and a traveling section C for impregnation which is set in the runway after the drug liquid application part B, during which the adhesive sheet is run for a period necessary for the applied drug liquid to soak into the adhesive layer without contact of the drug liquid coated face of the adhesive layer with other members.

IPC Classes  ?

  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61K 9/70 - Web, sheet or filament bases

77.

ADHESIVE PREPARATION

      
Document Number 02611727
Status In Force
Filing Date 2007-11-21
Open to Public Date 2008-05-22
Grant Date 2013-04-02
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Iwao, Yoshihiro
  • Okubo, Katsuyuki
  • Okada, Katsuhiro
  • Matsuoka, Kensuke

Abstract

The invention provides an adhesive preparation including a backing, and a pressure-sensitive adhesive layer which contains a drug and is disposed on at least one side of the backing; in which the backing includes a polyester film having a thickness of 0.5 to 6.0 µm, and a polyester nonwoven fabric directly bound to the film. The pressure-sensitive adhesive layer preferably is directly or indirectly laminated on the nonwoven-fabric side of the backing. The adhesive preparation of the invention is flexible enough to comply to the skin and has reduced skin irritation and high stability.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/13 - Amines, e.g. amantadine
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

78.

ADHESIVE PHARMACEUTICAL PREPARATION

      
Document Number 02633027
Status In Force
Filing Date 2006-12-13
Open to Public Date 2007-06-21
Grant Date 2012-01-10
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Iwao, Yoshihiro
  • Okada, Katsuhiro
  • Ookubo, Katsuyuki

Abstract

In the adhesive pharmaceutical preparation of the invention, a pressure- sensitive adhesive layer is laminated on one side of the backing. The pressure-sensitive adhesive layer contains a branched monoalcohol having from 12 to 28 carbon atoms, a drug which is liquid at room temperature or around room temperature (in which, free base of bisoprolol is excluded) and a polyisobutylene pressure-sensitive adhesive. Accordingly, compatibility of the polyisobutylene pressure-sensitive adhesive with the drug can be specifically increased. As a result, not only it becomes possible to increase blending amount of the drug but also bleed of the drug from the pressure- sensitive adhesive layer can be suppressed and, what is more, the pressure-sensitive adhesion characteristics sufficient from the practical point of view can be obtained.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

79.

PERCUTANEOUS ABSORPTION-TYPE PHARMACEUTICAL PREPARATIONS

      
Document Number 02558432
Status In Force
Filing Date 2006-09-01
Open to Public Date 2007-03-05
Grant Date 2012-10-16
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Yusa, Yoshimi
  • Yamamoto, Keiji
  • Kawashima, Tooru

Abstract

A percutaneous absorption-type pharmaceutical preparation containing a sublimation drug is provided, where from a plaster layer, a drug is released as volatile substance with a lapse of time, but the released drug has no adverse effect on the handling of the preparation, and the quality of the preparation is maintained in storage over a long period of time. A percutaneous absorption-type pharmaceutical preparation, which comprises: a support comprising a plastic film and a nonwoven fabric; and a plaster layer containing a sublimation drug, wherein the plastic film and the nonwoven fabric are laminated with an adhesive having a glass transition temperature of 10°C or higher, and the plaster layer is laminated on opposite side of the plastic film surface that the nonwoven fabric is laminated with.

IPC Classes  ?

  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin

80.

ADHESIVE AND LAMINATE

      
Document Number 02544709
Status In Force
Filing Date 2006-04-24
Open to Public Date 2006-10-28
Grant Date 2012-12-04
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Akemi, Hitoshi
  • Inosaka, Keigo
  • Sekiya, Junichi
  • Saito, Junichi
  • Hosaka, Yoshifumi

Abstract

The present invention provides an adhesive capable of affording an adhesive layer showing reduced stickiness, reduced cohesive failure and the like. An adhesive containing a copolymer obtained by copolymerizing monomers containing a (meth)acrylic acid alkyl ester as a main component, and a vinyl monomer having a hydroxyl group and/or a carboxyl group and which has an average molecular radius of not less than 70 nm as measured by a multi angle laser light scattering method.

IPC Classes  ?

81.

DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS

      
Document Number 02595517
Status In Force
Filing Date 2005-12-22
Open to Public Date 2006-06-29
Grant Date 2013-09-24
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Kato, Junji
  • Sato, Yasushi

Abstract

An astrocyte-specific drug carrier containing a retinoid derivative and/or a vitamin A analog as a constituent; a drug delivery method with the use of the same; a drug containing the same; and a therapeutic method with the use of the drug. By binding a drug carrier to a retinoid derivative such as vitamin A or a vitamin A analog or encapsulating the same in the drug carrier, a drug for therapeutic use can be delivered specifically to astrocytes. As a result, an astrocyte-related disease can be efficiently and effectively inhibited or prevented while minimizing side effects. As the drug inhibiting the activity or growth of astrocytes, for example, a siRNA against HSP47 which is a collagen-specific molecule chaperone may be encapsulated in the drug carrier. Thus, the secretion of type I to type IV collagens can be inhibited at the same time and, in its turn, fibrosis can be effectively inhibited.

IPC Classes  ?

  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • A61K 9/107 - Emulsions
  • A61K 9/127 - Liposomes
  • A61K 9/50 - Microcapsules
  • A61K 9/51 - Nanocapsules
  • A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups

82.

DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS

      
Document Number 02820728
Status In Force
Filing Date 2005-12-22
Open to Public Date 2006-06-29
Grant Date 2016-01-26
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Niitsu, Yoshiro
  • Kato, Junji
  • Sato, Yasushi

Abstract

An astrocyte-specific drug carrier containing a retinoid derivative and/or a vitamin A analog as a constituent; a drug delivery method with the use of the same; a drug containing the same; and a therapeutic method with the use of the drug. By binding a drug carrier to a retinoid derivative such as vitamin A or a vitamin A analog or encapsulating the same in the drug carrier, a drug for therapeutic use can be delivered specifically to astrocytes. As a result, an astrocyte-related disease can be efficiently and effectively inhibited or prevented while minimizing side effects. As the drug inhibiting the activity or growth of astrocytes, for example, a siRNA against HSP47 which is a collagen-specific molecule chaperone may be encapsulated in the drug carrier. Thus, the secretion of type I to type IV collagens can be inhibited at the same time and, in its turn, fibrosis can be effectively inhibited.

IPC Classes  ?

83.

ADHESIVE MATERIAL AND ADHESIVE PREPARATION

      
Document Number 02514636
Status In Force
Filing Date 2005-08-04
Open to Public Date 2006-02-12
Grant Date 2012-11-27
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Akemi, Hitoshi
  • Ninomiya, Kazuhisa
  • Kuroda, Hidetoshi
  • Matsuoka, Kensuke
  • Saeki, Yuji
  • Nishimura, Masato

Abstract

The present invention provides an adhesive material to be adhered to the skin etc., which maintains, for a certain time period after adhesion thereof to the skin surface, suitable adhesiveness that does not allow easy peeling or cause irritation to the skin, and which permits, when it is to be peeled off from the skin surface after the lapse of a desired certain time period, easy peeling without causing pain or physical irritation, and an adhesive preparation containing the adhesive material and a percutaneously absorbable drug in the adhesive layer. Specifically, the present invention provides an adhesive material containing a support and an adhesive layer laminated on one surface of the support, wherein the adhesive layer has an apparent viscosity at 30°C of 0.2×10 4 to 10×10 4Pa.cndot.s and comprises two kinds of synthetic rubbers having different flowability.

IPC Classes  ?

  • A61L 15/58 - Adhesives
  • A61K 9/70 - Web, sheet or filament bases
  • A61L 15/22 - Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials

84.

ADHESIVE PREPARATION PACKAGE

      
Document Number 02511166
Status In Force
Filing Date 2005-06-29
Open to Public Date 2006-01-01
Grant Date 2012-12-04
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Ninomiya, Kazuhisa
  • Goshima, Shoji

Abstract

The present invention provides an adhesive preparation package containing an adhesive preparation and a packaging film(s) enclosing said preparation, the packaging films being heat-sealed around the adhesive preparation, wherein the heat-sealed portion of the packaging film comprises an embossed heat-sealed portion and a flat heat-sealed portion, and the embossed heat-sealed portion and the flat heat-sealed portion each form a pattern surrounding the periphery of the adhesive preparation. The adhesive preparation package of the present invention is free of occurrence of pinholes in a heat-sealed portion and can maintain superior air-tightness and sterility.

IPC Classes  ?

  • B65D 75/30 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
  • A61L 15/44 - Medicaments
  • A61L 15/58 - Adhesives
  • B65B 11/50 - Enclosing articles, or quantities of material, by disposing contents between two sheets, e.g. pocketed sheets, and securing their opposed free margins
  • B65D 75/20 - Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks doubled around contents and having their opposed free margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding

85.

POROUS RESIN BEAD AND PRODUCTION METHOD THEREOF

      
Document Number 02479586
Status In Force
Filing Date 2004-08-27
Open to Public Date 2005-02-28
Grant Date 2013-05-28
Owner NITTO DENKO CORPORATION (Japan)
Inventor
  • Mori, Kenjiro
  • Matsunawa, Ayako
  • Konishi, Tatsuya

Abstract

The present invention provides, as a resin bead which can be developed for use completely different from the use of conventional polystyrene resin beads, a porous resin bead made from a styrene-hydroxystyrene-divinylbenzene copolymer, which contain a hydroxyl group in an amount of 10 - 1000 µmol/g, and further, a production method of a porous resin bead made from a styrene-hydroxystyrene-divinylbenzene copolymer; which contains suspension copolymerization of a styrene monomer, an acyloxystyrene monomer and a divinylbenzene monomer using an organic solvent (containing at least hydrocarbon and alcohol) and water, followed by hydrolysis reaction.

IPC Classes  ?

  • C08F 212/02 - Monomers containing only one unsaturated aliphatic radical
  • C08F 8/12 - Hydrolysis
  • C08F 212/08 - Styrene
  • C08F 212/14 - Monomers containing only one unsaturated aliphatic radical containing one ring substituted by hetero atoms or groups containing hetero atoms
  • C08F 212/36 - Divinylbenzene
  • C08J 5/00 - Manufacture of articles or shaped materials containing macromolecular substances
  • C08J 9/00 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof