Electrochemical cells and methods of preventing overheating of the same are disclosed. An electrochemical cell may include a cathode and an anode. The anode may include a lithium alloy. The anode may be configured to reduce a maximum rate of ion transfer between the anode and the cathode in response to an occurrence of a fault condition. The lithium alloy may comprise at least 70 weight percent lithium to 99 weight percent lithium.
Systems and methods for evaluating a proposed valve-in-valve procedure for a patient in which a replacement transcatheter aortic valve will be deployed within a first bioprosthetic aortic valve. The methods include selecting predetermined benchmark measurements of a valve-in-valve combination. Images of anatomy of the patient are received. Anatomical measurements of the first bioprosthetic valve are obtained from the received images. The predetermined benchmark measurements and the anatomical measurements are reviewed. Based, at least in part, upon the review, risks of a valve-in-valve procedure for the patient are evaluated. The methods of the present disclosure can be used on baseline scans of a patient without a first bioprosthetic valve implanted; under these circumstances, dimensions of the first valve are determined by benchmark measurements. Where methods of the present disclosure are used on post-first implant scans, then the dimensions of the first valve are determined from the post-implant scans.
An implantable medical lead includes a lead body extending from a proximal end to a distal end. The lead body includes an inner insulation layer and an outer insulation layer. The lead further includes a sleeve mechanically supported by the lead body at the distal end of the lead body. The lead further includes an uninsulated conductor coil. The uninsulated conductor coil includes a first portion having a first inner diameter, and a second portion having a second inner diameter and extending distally from the outer insulation layer. The first portion is positioned between the inner insulation layer and the outer insulation layer. The second inner diameter is greater than the first inner diameter. An outer surface of the second portion is exposed.
Techniques related to classifying a posture state of a living body are disclosed. One aspect relates to sensing at least one signal indicative of a posture state of a living body. Posture state detection logic classifies the living body as being in a posture state based on the at least one signal, wherein this classification may take into account at least one of posture and activity state of the living body. The posture state detection logic further determines whether the living body is classified in the posture state for at least a predetermined period of time. Response logic is described that initiates a response as a result of the body being classified in the posture state only after the living body has maintained the classified posture state for at least the predetermined period of time. This response may involve a change in therapy, such as neurostimulation therapy, that is delivered to the living body.
An implantable medical lead includes a lead body extending from a proximal end to a distal end. The lead body includes an inner insulation layer and an outer insulation layer. The lead further includes a sleeve mechanically supported by the lead body at the distal end of the lead body. The lead further includes an uninsulated conductor coil. The uninsulated conductor coil includes a first portion having a first inner diameter, and a second portion having a second inner diameter and extending distally from the outer insulation layer. The first portion is positioned between the inner insulation layer and the outer insulation layer. The second inner diameter is greater than the first inner diameter. An outer surface of the second portion is exposed.
A system comprises one or more implantable monitoring devices configured to continuously sense a plurality of physiological signals of a subject and collect parameter data of the subject based on the sensed physiological signals. At least one monitoring device of the one or more monitoring devices comprises a housing configured for subcutaneous implantation in the subject and a plurality of electrodes positioned on the housing. The at least one monitoring device is configured to continuously sense at least one physiological signal of the plurality of physiological signals via the plurality of electrodes. The system further comprises processing circuitry configured to determine a mental state of the subject based on at least one of the sensed physiological signals or the parameter data.
Example techniques, devices, and systems are described herein. An example device includes stimulation generation circuitry, sensing circuitry, and processing circuitry. The processing circuitry is configured to control the stimulation generation circuitry to generate a first stimulation signal having a first stimulation recharge parameter for delivery to target anatomy and receive from the sensing circuitry a sensed evoked response signal. The processing circuitry is configured to analyze the sensed evoked response signal for one or more artifacts and adjust, based on the one or more artifacts, the first stimulation recharge parameter to determine a second stimulation recharge parameter. The processing circuitry is also configured to control the stimulation generation circuitry to generate a second stimulation signal having the second stimulation recharge parameter for delivery to the target anatomy.
An example fixation component for an implantable medical device (IMD) includes a base and a plurality of tines configured be deployed with a target deployment stiffness to engage tissue a target implant site while maintaining a target deflection stiffness after deployment. The base defines a longitudinal axis of the fixation component and is fixedly attached near the distal end of the IMD. Each tine is spaced apart from one another around a perimeter of the distal end of the IMD and extend from the base. A shape of each tine is selected to control each of the target deployment stiffness and target deflection stiffness.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
B21D 39/02 - Application of procedures in order to connect objects or parts, e.g. coating with sheet metal otherwise than by plating; Tube expanders of sheet metal by folding, e.g. connecting edges of a sheet to form a cylinder
9.
TEMPORARY PACING LEAD MANAGEMENT SYSTEM WITH EXPANDABLE MEMBER
This disclosure describes a system comprising an electrical lead, an implantable medical device, wherein the electrical lead is configured to be electrically connected to the implantable medical device, and wherein the implantable medical device is configured to deliver an electrical therapy to tissue of a patient via the electrical lead, and an expandable member configured to be disposed over the implantable medical device and an excess portion of the electrical lead. The expandable member comprises a first portion defining an inner volume configured to retain the implantable medical device and the excess portion of the electrical lead, and a second portion connected to a proximal end of the first portion, the second portion configured to be disposed over at least a part of the first portion of the expandable member, wherein the expandable member is configured to control a length of the electrical lead within vasculature of the patient..
Adaptive cardiac conduction system pacing therapy for multi-chamber devices may monitor electrical activity of a patient's heart and select a cardiac conduction system pacing therapy pacing mode based on the monitored electrical activity. For instance, one or more metrics such as P-wave-to-R-wave interval and QRS complex width may be determined based on the monitored electrical activity, and one of an inhibited pacing mode, a ventricular fusion pacing mode, an atrioventricular synchronous pacing mode, and an atrial fibrillation pacing mode may be selected based on the determined one or more metrics.
A61N 1/368 - Heart stimulators controlled by a physiological parameter, e.g. by heart potential comprising more than one electrode co-operating with different heart regions
An example medical device for aspirating material from a patient includes a flow switch including an anvil, an actuator, and a surface feature on at least one of the anvil and actuator. The flow switch is configured to move the actuator away from the anvil to create a flow path for the aspiration of the material and to move the actuator toward the anvil to reduce the flow path by creating at least one channel defined by the surface feature.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
A61M 39/28 - Clamping means for squeezing flexible tubes, e.g. roller clamps
A system including an implantable medical device (IMD) configured to deliver an anti-tachycardia pacing (ATP) therapy to a patient and an external device including: communications circuitry configured to communicate with the IMD; and processing circuitry configured to: receive, via the communications circuitry, a request to connect from the IMD, determine whether the IMD is connected to the external device, and based on a determination that the IMD is connected to the external device, transmit instructions, via the communications circuitry, to the IMD to deliver the ATP therapy to the patient.
In some examples, an implantable medical device includes a device body extending from a proximal portion to a distal portion along a longitudinal axis, a fixation component, and an electrode interface assembly. The fixation component includes a penetrator tine extending away from the distal portion of the device body and configured to penetrate a tissue. The electrode interface assembly includes a leadlet extending away from the distal portion of the device body, an elongated body extending away from the distal portion of the device body the elongated body defining a recess and a groove, wherein the groove is configured to receive the leadlet, and an electrode extending from the elongated body and disposed within the recess.
A leadless neurostimulation device including a header unit having at least one primary electrode having a contact surface that defines an external surface on a side of the device, an outer housing that forms a side of the header unit opposite of the contact surface of the primary electrode, and a dielectric mount that receives at least a portion of the primary electrode and at least partially surrounds the primary electrode, the dielectric mount being configured to electrically insulate the primary electrode from the outer housing, the dielectric mount being received and fixed within a recessed portion of the outer housing, and a housing having a secondary electrode positioned on the same side of the leadless neurostimulation device as the primary electrode, the primary electrode and the secondary electrode being configured to transmit an electrical stimulation signal therebetween to provide electrical stimulation therapy to a tibial nerve of a patient.
An example medical device for aspirating material from a patient includes a flow switch including an anvil, an actuator, and a surface feature on at least one of the anvil and actuator. The flow switch is configured to move the actuator away from the anvil create a flow path for the aspiration of the material and to move the actuator toward the anvil to reduce the flow path by creating at least one channel defined by the surface feature.
A61M 1/00 - Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
16.
CYLINDRICAL ELECTROCHEMICAL CELLS AND METHODS OF FORMING THE SAME
An electrochemical cells and methods of making the same are disclosed. An electrochemical cell may include a cell housing and a cell core disposed in the cell housing. The cell body may extend along a longitudinal axis from a distal end to a proximal end. The cell core may include a cathode electrode, an anode electrode, and a separator disposed between the cathode electrode and the anode electrode. The cathode electrode may define a plurality of cathode windings around the longitudinal axis. Each cathode winding may include a porous conductive strip and a cathode active material disposed on the porous conductive strip. The anode electrode may be disposed around the cathode electrode.
H01M 4/74 - Meshes or woven material; Expanded metal
H01M 10/04 - Construction or manufacture in general
H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodes; Lithium-ion batteries
H01M 10/0587 - Construction or manufacture of accumulators having only wound construction elements, i.e. wound positive electrodes, wound negative electrodes and wound separators
17.
MEDICAL DEVICE AND METHOD FOR DETERMINING RISK OF A CARDIAC EVENT
A medical device is configured to receive up to two cardiac electrical signals. For each cardiac cycle of multiple cardiac cycles, the device may derive a T-wave loop in at least two dimensions using one or two of the up to two cardiac electrical signals. The medical device may determine a repolarization measurement representative of each T-wave loop and determine a change in the repolarization measurement from a previously determined repolarization measurement. The device may determine a metric of the determined changes in the repolarization measurements.
Adaptive cardiac conduction system pacing therapy may monitor electrical activity of a patient's heart and select a cardiac conduction system pacing therapy pacing mode based on the monitored electrical activity. For instance, one or more metrics such as P- wave-to-R-wave interval and QRS complex width may be determined based on the monitored electrical activity, and one of an inhibited pacing mode, a ventricular fusion pacing mode, an atrioventricular synchronous pacing mode, and an atrial fibrillation pacing mode may be selected based on the determined one or more metrics.
A61B 5/366 - Detecting abnormal QRS complex, e.g. widening
A61N 1/365 - Heart stimulators controlled by a physiological parameter, e.g. by heart potential
A61N 1/368 - Heart stimulators controlled by a physiological parameter, e.g. by heart potential comprising more than one electrode co-operating with different heart regions
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61N 1/375 - Constructional arrangements, e.g. casings
This disclosure describes a system comprising an electrical lead, an implantable medical device, wherein the electrical lead is configured to be electrically connected to the implantable medical device, and the implantable medical device is configured to deliver an electrical therapy to tissue of a patient via the electrical lead, and an expandable member configured to be disposed over the implantable medical device and an excess portion of the electrical lead, wherein the expandable member is configured to control movement of the electrical lead within vasculature of the patient.
A system including an electrical lead, an implantable medical device, wherein the electrical lead is configured to be electrically connected to the implantable medical device, and the implantable medical device is configured to deliver an electrical therapy to tissue of a patient via the electrical lead, a sheath configured to be at least partially disposed within vasculature of the patient and configured to receive the electrical lead such that a distal portion of the electrical lead is placed within the vasculature through the sheath, and a lead management device connected to the implantable medical device and the sheath, wherein the lead management device is configured to secure an excess portion of the electrical lead, and wherein the lead management device is configured to control movement of the electrical lead within the vasculature of the patient.
Devices, systems, and techniques are described that use electric field imaging (often referred to as the sensed stimulation artifact representative of a delivered stimulus) as an informative feedback signal to provide closed loop control of electrical stimulation therapy. In some examples, the electric field imaging may be used in combination with other feedback signals, such as ECAP do monitor and adjust the delivered electrical stimulation therapy.
Broad cerebrospinal fluid (CSF) distribution of an agent is achievable by delivering the agent in a liquid formulation to the CSF at flow rates less than 500 microliters per hour, such as between about 2 microliters per hour and about 100 microliters per hour.
An example medical device includes a memory; and processing circuitry coupled to the memory, the processing circuitry is configured to: receive, from one or more electrodes coupled to the medical device, a cardiac signal; determine a risk of noise being greater than or equal to a noise risk threshold or an active amount of the noise being greater than or equal to an active noise threshold; and in response to determining the risk of noise is greater than or equal to the noise risk threshold or the active amount of noise is greater than or equal to the active noise threshold, activate a filter to filter the noise from the cardiac signal.
A61B 17/12 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A fixation component includes tines extending from a base portion of the fixation component. Each tine is elastically deformable between a pre-set position and an open position. Each tine includes a hook segment extending from a proximal end near the base portion to a distal end. Each tine also includes a distal segment extending from the distal end of the hook segment to a tissue-piercing tip. When positioned in the pre-set position, the hook segment extends along a pre-set curvature that encloses an angle between 135 degrees and 270 degrees, and the distal segment extends away from a longitudinal axis of the fixation component.
A medical device lead connector includes electrically conducting contact rings spaced apart by an electrically insulating ring and in axial alignment. The electrically conducting contact ring and the insulating ring having an interface bond on an atomic level.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/375 - Constructional arrangements, e.g. casings
B23K 20/02 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating by means of a press
H01R 13/187 - Pins, blades or sockets having separate spring member for producing or increasing contact pressure the spring member being in the socket
H01R 24/58 - Contacts spaced along longitudinal axis of engagement
H01R 43/02 - Apparatus or processes specially adapted for manufacturing, assembling, maintaining, or repairing of line connectors or current collectors or for joining electric conductors for soldered or welded connections
27.
METHODS OF PREPARING BALLOON EXPANDABLE CATHETERS FOR CARDIAC AND VASCULAR INTERVENTIONS
Methods for purging a balloon catheter of air. An inflation fluid is inserted into a balloon and an inflation lumen of a balloon catheter. The inflation lumen is in fluid communication with the balloon. The balloon catheter is positioned in an inverted orientation with a distal end thereof disposed below a proximal end thereof. The distal end of the balloon catheter includes a balloon. A vibration source is positioned in direct contact with an outer surface of the balloon catheter. The balloon catheter is vibrated via the vibration source. A vacuum is applied or pulled on the inflation lumen of the balloon catheter. The steps of vibrating the balloon catheter and applying the vacuum are performed simultaneously.
Example devices and techniques are described herein for determining a relative state-of-charge of a battery. An example device includes memory, a battery, a temperature sensor and processing circuitry coupled to the memory and the temperature sensor. The temperature sensor may be configured to sense a battery temperature. The processing circuitry may be configured to estimate an end-of-discharge state-of-charge of the battery. The processing circuitry may be configured to estimate a remaining capacity of the battery. The processing circuitry may be configured to estimate a full charge capacity of the battery. The processing circuitry may be configured to estimate a relative state-of-charge of the battery and generate a representation of the estimate of the relative state-of-charge of the battery for output.
G01R 31/36 - Arrangements for testing, measuring or monitoring the electrical condition of accumulators or electric batteries, e.g. capacity or state of charge [SoC]
G01R 31/367 - Software therefor, e.g. for battery testing using modelling or look-up tables
G01R 31/3842 - Arrangements for monitoring battery or accumulator variables, e.g. SoC combining voltage and current measurements
Goods: Medical apparatus and equipment for use in electronic acquisition, capture, processing, presentation, storage and transmission of patient's medical and physiological data for use in programming, monitoring and testing implanted cardiac devices.
30.
DIRECTIONAL CONTROL OF MULTI-COIL ARRAY FOR APPLICATIONS IN RECHARGE SYSTEMS
A system that includes a power transmitting antenna (124) with a coiled conductor defined by a first axis and a second axis perpendicular to the first axis, where a single plane comprises the first axis and the second axis. The system includes a support layer (140, 142) comprising: a substantially planar top surface and a substantially planar bottom surface opposite the substantially planar top surface arranged parallel to the plane. The support layer also comprises a material with a predetermined resiliency. The support layer is configured to support a mass of a user and maintain a predetermined spacing between the plane of the power transmitting antenna and the user during compression of the material from the mass of the user.
H02J 50/40 - Circuit arrangements or systems for wireless supply or distribution of electric power using two or more transmitting or receiving devices
H02J 50/00 - Circuit arrangements or systems for wireless supply or distribution of electric power
H02J 50/10 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling
H02J 50/80 - Circuit arrangements or systems for wireless supply or distribution of electric power involving the exchange of data, concerning supply or distribution of electric power, between transmitting devices and receiving devices
Example devices and techniques are described herein for determining a relative state-of-charge of a battery. An example device includes memory, a battery, a temperature sensor and processing circuitry coupled to the memory and the temperature sensor. The temperature sensor may be configured to sense a battery temperature. The processing circuitry may be configured to estimate an end-of-discharge state-of-charge of the battery. The processing circuitry may be configured to estimate a remaining capacity of the battery. The processing circuitry may be configured to estimate a full charge capacity of the battery. The processing circuitry may be configured to estimate a relative state-of-charge of the battery and generate a representation of the estimate of the relative state-of-charge of the battery for output.
G01R 31/396 - Acquisition or processing of data for testing or for monitoring individual cells or groups of cells within a battery
G01R 31/367 - Software therefor, e.g. for battery testing using modelling or look-up tables
G01R 31/3842 - Arrangements for monitoring battery or accumulator variables, e.g. SoC combining voltage and current measurements
H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells
H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
A capsule of a delivery system for a transcatheter heart valve prosthesis includes markers for rotationally orienting the capsule within a native valve. The capsule includes markers that are sized and located on the capsule such that when viewed in a cusp overlap viewing angle image, the markers indicate whether the capsule is in a desired rotational orientation. Methods for rotationally aligning a capsule of a delivery system containing a transcatheter heart valve prosthesis within a native valve are also provided.
A computing device comprises communication circuitry configured to wirelessly communicate with a sensor device, one or more output devices, and processing circuitry. The processing circuitry is configured to receive episode data for an acute health event detected by the sensor device via the communication circuitry, the episode data transmitted by the sensor device in response to detecting the acute health event. The processing circuitry is configured to apply one or more machine learning models to each segment of a plurality of segments of the episode data to determine a respective classification of a plurality of predetermined classifications for each segment of the plurality of segments, determine a classification of the acute health event from the plurality of predetermined classifications based on the respective classifications of the plurality of segments, and determine whether to control the one or more output devices to output an alarm based on the classification.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A computing device comprises communication circuitry configured to wirelessly communicate with a sensor device on a patient or implanted within the patient, one or more output devices, and processing circuitry. The processing circuitry is configured to receive episode data for an acute health event detected by the sensor device via the communication circuitry, the episode data transmitted by the sensor device in response to detecting the acute health event, determine an alarm context in response to receiving the episode data, configure an alarm for the acute health event based on the alarm context, and control the one or more output devices to output the alarm configured based on the alarm context.
A system comprises a cloud computing system, a computing device, and a sensor device. The sensor device is configured to sense an electrocardiogram of the patient, detect a ventricular tachyarrhythmia based on sensed electrocardiogram, and wirelessly communicate with the computing device in response to the detection of the ventricular tachyarrhythmia. Based on the wireless communication from the sensor device, the computing device is configured to at least one of output a local alarm or transmit an alert to an emergency medical service via the cloud computing system. Processing circuitry of at least one of the sensor device, the computing device, or the cloud computing system is configured to determine QT intervals based on the electrocardiogram, and transmit a message indicating QT prolongation of the patient to a clinician based on a determination that the QT intervals satisfy one or more QT prolongation criteria.
Systems, devices, and techniques for adjusting electrical stimulation based on sensed ECAP signals. For example, processing circuitry is configured to control delivery of a first train of electrical stimulation pulses at a first frequency to a first target tissue and control delivery of a second train of electrical stimulation pulses at a second frequency to a second target tissue different from the first target tissue. The processing circuitry can also receive an ECAP signal elicited by a pulse of the second train of electrical stimulation pulses, adjust, based on the ECAP signal, a first value of a parameter that at least partially defines the first tram of electrical stimulation pulses to a second value, and, responsive to adjusting the first value of the parameter to the second value, control delivery of subsequent pulses of the first tram of electrical stimulation pulses according to the second value of the parameter.
An apparatus for fastening around a cranial burr hole includes a substantially flat core and a shell encapsulating a ring portion of the core. The shell defines an orifice substantially centered within the ring portion, and has a contoured lower surface to match the cranial curvature. Pliable arms of the core extend laterally from the ring portion, each being terminated by a fastener member. A central portion of a placement tool for the apparatus has a lower part configured to extend through the apparatus orifice, and an upper part from which first and second arms of the tool extend laterally. Each tool arm is terminated with a receptacle to hold a bone screw, and, when the tool central portion lower part extends through the apparatus orifice, each receptacle aligns with a corresponding fastener member, and lower openings of the receptacles are generally oriented along the contoured lower surface.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 90/11 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
A61M 25/04 - Holding devices, e.g. on the body in the body, e.g. expansible
A method comprises identifying P-waves within a cardiac signal stored by a medical device for a cardiac episode detected by the medical device, and calculating a gain factor for display of the cardiac signal based on the identified P-waves.
A computing device comprises communication circuitry configured to wirelessly communicate with a sensor device on a patient or implanted within the patient, one or more output devices, and processing circuitry. The processing circuitry is configured to receive episode data for an acute health event detected by the sensor device via the communication circuitry, the episode data transmitted by the sensor device in response to detecting the acute health event. The processing circuitry is configured to classify the acute health event as one of a plurality of classifications by at least applying one or more machine learning models to each segment of a plurality of segments of the episode data, and applying one or more non¬ machine learning rules to each segment of the plurality of segments. The processing circuitry is configured to determine whether to control the one or more output devices to output an alarm based on the classification.
A61B 5/29 - Invasive for permanent or long-term implantation
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 5/33 - Heart-related electrical modalities, e.g. electrocardiography [ECG] specially adapted for cooperation with other devices
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable computer software and mobile applications incorporating AI algorithms used to operate and manage medical monitors; Downloadable computer software and mobile applications incorporating AI algorithms used to analyze, monitor and transmit information regarding cardiac conditions, activities and events; Feature of downloadable computer software and mobile applications, namely, software containing algorithms for analyzing, monitoring and transmitting information regarding cardiac conditions, activities and events; Downloadable computer software and mobile applications for analyzing patient data to identify risk of stroke; Downloadable computer software and mobile applications for analyzing patient data to detect stroke; Downloadable computer software and mobile applications for analyzing patient data to detect atrial fibrillation
41.
MEDICAL DEVICE AND METHOD FOR DETERMINING ATRIOVENTRICULAR SYNCHRONY
A medical device is configured to sense a cardiac signal that includes far field ventricular event signals and determine a ventricular activity metric from the sensed cardiac signal. The ventricular activity metric may be representative of a ventricular rate or an atrioventricular time interval. The medical device is configured to determine an atrioventricular synchrony metric based on the ventricular activity metric and generate an output based on the atrioventricular synchrony metric. The device may include a memory configured to store data corresponding to the atrioventricular synchrony metric.
A61N 1/365 - Heart stimulators controlled by a physiological parameter, e.g. by heart potential
A61N 1/368 - Heart stimulators controlled by a physiological parameter, e.g. by heart potential comprising more than one electrode co-operating with different heart regions
Systems and methods for sampling a fluid is provided. The system may include a port implanted in a patient and a catheter implanted in the patient and in fluid communication with the port. The catheter may enable fluid sampling from the patient and delivery of the fluid sample via the port.
A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
A transcatheter heart valve prosthesis and a method of assembling the transcatheter heart valve prosthesis are disclosed. The heart valve prosthesis includes a valve-skirt assembly having an inner skirt, a frame, an outer wrap backing and an outer wrap. The method includes: tacking the valve-skirt assembly within the frame; attaching the inner skirt below commissure posts of the frame; attaching commissures of the valve component to the commissure posts; attaching a plurality of outer wrap backings to the inner skirt; attaching the outer wrap backings and the inner skirt to the frame; attaching tissue bumpers to struts in an outflow section of the frame; attaching an outer wrap and the inner skirt to the frame; attaching the outer wrap to the inner skirt proximate inflow edges thereof; and attaching the outer wrap to the inner skirt and to the outer wrap backings proximate respective outflow edges thereof.
A medical device is configured to detect an atrial tachyarrhythmia episode. The device senses a cardiac signal, identifies R-waves in the cardiac signal attendant ventricular depolarizations and determines classification factors from the R-waves identified over a predetermined time period. The device classifies the predetermined time period as one of unclassified, atrial tachyarrhythmia and non-atrial tachyarrhythmia by comparing the determined classification factors to classification criteria. A classification criterion is adjusted from a first classification criterion to a second classification criterion after at least one time period being classified as atrial tachyarrhythmia. An atrial tachyarrhythmia episode is detected by the device in response to at least one subsequent time period being classified as atrial tachyarrhythmia based on the adjusted classification criterion.
An example medical device includes processing circuitry configured to determine an electrode impedance value for each of one or more electrodes of a lead coupled to the medical device, identify one or more of the electrodes having electrode impedance values that are greater than electrode impedance values of other electrodes of the lead, from the identified one or more electrodes, determine a recommendation of electrodes to use for sensing a signal, and output information indicative of the recommendation.
Systems, apparatus, methods and computer-readable storage media facilitating trusted pairing between an implantable medical device (IMD) and an external device are provided. In one embodiment, an IMD includes a housing configured to be implanted within a patient, a memory and circuitry within the housing and a processor that executes executable components stored in the memory. The executable components can include: a communication component configured to initiate establishing a telemetry connection with an external device in accordance with a first telemetry protocol based on reception of a request, from the external device, to establish the telemetry connection with the IMD using the first telemetry protocol; and a validation component configured to restrict establishment of the telemetry connection with the external device in accordance with the first telemetry protocol based on reception of validation information from the external device, wherein provision of the validation information is excluded from the first telemetry protocol.
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
A medical device includes a motion sensor configured to produce a motion signal and a control circuit configured to set sensing control parameters and sense atrial events from the motion signal during ventricular cycles according to the sensing control parameters. In some examples, the control circuit is configured to determine a feature of the motion signal for at least some ventricular cycles, determine a metric of the motion signal based on the determined features, and adjust at least one of the sensing control parameters based on the metric.
A61N 1/375 - Constructional arrangements, e.g. casings
G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
48.
IDENTIFYING EJECTION FRACTION USING A SINGLE LEAD CARDIAC ELECTROGRAM SENSED BY A MEDICAL DEVICE
An example system for determining reduced ejection fraction includes two or more electrodes forming a single lead configured to capture a cardiac electrogram (EGM) signal of a patient, circuitry configured to: convert the EGM signal to a time -frequency domain using a continuous wavelet transform; and apply the converted EGM signal to a convolutional neural network to determine one or more of an amount of ejection fraction or a classification of ejection fraction.
A61B 5/02 - Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
49.
MULTI-MODALITY BALLOON CATHETER INCLUDING LITHOTRIPSY BALLOON
A multi-modality catheter is configured to treat a calcified lesion of a body lumen. The multi-modality catheter includes an integrated intravascular lithotripsy balloon and second treatment balloon. The intravascular lithotripsy balloon includes a shock wave emitter to produce a shock wave for modifying the calcified lesion. The second treatment balloon is configured to treat the calcified lesion.
A medical device includes wake circuitry and telemetry circuitry. The wake circuitry is configured to receive a first set of data from a device associated with the medical device, where the first set of data is received at a frequency band. The wake circuitry is configured to output a set of pulses based on the first set of data. The wake circuitry is configured to detect a data pattern using the set of pulses. The wake circuitry is configured to output an activation signal in response to a determination that the data pattern satisfies a data pattern requirement. The telemetry circuitry is configured to output a second set of data in response to receiving the activation signal. The second set of data is transmitted at the frequency band. The telemetry circuitry is configured to establish a communication session with the device using the second set of data.
A medical system including an implantable medical device (IMD) configured to position within a heart of a patient. The IMD is configured to receive imparted forces from a tissue wall of a beating heart when a fixation element of the IMD is implanted in the tissue wall. The IMD includes a motion sensor configured to sense the motion of the IMD produced by forces imparted to the IMD from the tissue wall. Processing circuitry is configured to compare the motion sensed with a representative cardiac activity. The processing circuitry is configured to assess the engagement of the fixation element and the tissue wall based on the comparison. The processing circuitry may be configured to assess the engagement as a clinician causes the fixation element to engage the tissue wall.
A lithotripsy balloon catheter may include a shock wave emitter that is selectively movable longitudinally within the balloon to adjust a longitudinal position of the shock wave emitter relative to the balloon. A lithotripsy balloon catheter may include a unipolar electrode that produces an electrical arc when a voltage is applied to the unipolar electrode thereby creating a shock wave within the balloon. A grounding conductor for the shock wave emitter may be coupled to the proximal end portion of the catheter body and configured to be connected to ground. A lithotripsy balloon catheter may include a unipolar electrode in communication with an electrical source of energy and configured to deliver energy from the electrical energy source to the fluid in the balloon thereby creating a shock wave within the balloon. Ceramic insulation may be disposed on the unipolar electrode to focus energy at a tip of the unipolar electrode.
A medical device system includes a medical device comprising one or more electrodes and configured to generate electrical cardiac data based on a cardiac signal sensed from a patient via the one or more electrodes, a memory configured to store a machine learning model and a plurality of sets of training data, and processing circuitry in communication with the memory. The processing circuitry is configured to apply the machine learning model to the electrical cardiac data to determine a value of a metric of left ventricular (LV) dysfunction. The machine learning model is trained based on the plurality of sets of training data. Each set of training data of the plurality of sets of training data includes a set of training electrical cardiac data and information indicating one or more values of the metric of LV dysfunction corresponding to the set of training electrical cardiac data.
A61B 5/02 - Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
Systems, devices, and techniques for adjusting electrical stimulation based on a posture state of a patient are described. For example, processing circuitry is configured to receive an input from a user adjusting an informed stimulation parameter that at least partially defines a plurality of informed pulses, determine a ratio of a first value of an informed stimulation parameter to a first value of a control stimulation parameter that at least partially defines a plurality of control pulses, change, according to the input, the first value of the informed stimulation parameter to a second value of the informed stimulation parameter, and change, based on the input and the ratio, the first value of the control stimulation parameter to a second value of the control stimulation parameter. The processing circuitry' can then control delivery of the adjusted control pulses and informed pulses.
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 5/388 - Nerve conduction study, e.g. detecting action potential of peripheral nerves
A61N 1/372 - Arrangements in connection with the implantation of stimulators
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A pair of cooperating catheters, chosen from an inner catheter and two possible outer catheters, are used together to provide rapid access to the Left heart for diagnostic or therapeutic interventions. The pair of catheters can be used to carry out an electrographic determination of the location of the Fossa Ovalis on the septum. Features on the Catheter system permit quick and reliable confirmation of the catheter location via echo or x-rays. Once across the septum the inner catheter is removed from the outer catheter and a standard intervention may be carried out through the lumen of the outer catheter.
A system and method for detecting and verifying bradycardia/asystole episodes includes sensing an electrogram (EGM) signal. The EGM signal is compared to a primary threshold to sense events in the EGM signal, and at least one of a bradycardia or an asystole is detected based on the comparison. In response to detecting at least one of a bradycardia or an asystole, the EGM signal is compared to a secondary threshold to sense events under-sensed by the primary threshold. The validity of the bradycardia or the asystole is determined based on the detected under-sensed events.
The present disclosure relates to surrogate left ventricular activation times (110, 107, 107A) that is representative of, or correlates to, left ventricular activation times for use in determining left bundle branch (LBB) (8a) capture and LBB pacing configuration. The surrogate left ventricular activation times (110, 107, 107A) may be determined, or measured, from electrical activity monitored from one or more implanted electrodes (40, 42, 44, 46, 48, 50, 58, 61, 62, 64, 66) such as, for example, a LBB pacing electrode or an electrode located in the right ventricle (28).
A61N 1/368 - Heart stimulators controlled by a physiological parameter, e.g. by heart potential comprising more than one electrode co-operating with different heart regions
58.
INTEGRATED CARDIOVERTER DEFIBRILLATOR-MUSCLE STIMULATOR FOR CARDIOMYOPLASTY
An example implantable medical device includes a stimulating lead includes receive one or more signals indicative of one or more physiologic parameters; deliver electrical therapy to stimulate a muscle wrapped around a heart via one or more electrodes of a stimulating lead; and adjust an amount of the electrical therapy delivered, via the stimulating electrodes, based on the one or more physiologic parameters.
A method for ablating tissue by applying at least one pulse train of pulsed-field energy. The method includes delivering a pulse train of energy having a predetermined frequency to cardiac tissue, the pulse train including at least 60 pulses, an inter-phase delay between 0 μs and 5 μs, an inter-pulse delay of at least 5 μs, and a pulse width of 5 μs.
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents
In some examples, the disclosure relates to system, devices, and techniques for delivering electrical stimulation therapy to treat patient disorders. In one example, the disclosure is directed to a method including controlling, using processing circuitry, the delivery of an electrical stimulation therapy to a patient via a medical device, wherein the electrical stimulation therapy includes a plurality of bi-phasic pulses, each pulse of the bi- phasic pulses including a first phase followed by a second phase, and wherein the plurality of bi-phasic pulses are configured to reduce or block transmission of neural activity along nerve fibers.
Systems and methods for treating Inflammatory Bowel Disease (IBD) using neuromodulation are described herein. For example, IBD can be treated by delivering an electrical signal to one or more sacral nerves of a patient via an implanted signal delivery device positioned proximate one or more of the patient's sacral nerves. In some embodiments, the electrical signal can modulate neural activity in the patient, which may in turn reduce inflammation in the patient by altering an imbalance between the patient's sympathetic nervous system and parasympathetic nervous system, and/or modifying a threshold for an inflammatory response in the gastrointestinal system.
A loading system for loading a heart valve prosthesis into a delivery system includes a loading cone, a loading ring, and a valve seat. The loading cone includes a passageway extending therethrough, with the passageway including a tapered portion. The loading ring is configured to be coupled to the loading cone. The valve seat is configured to be coupled to the loading ring. The valve seat is rotatable relative to the loading ring when the valve seat and the loading ring are coupled together. The valve seat is configured to receive the heart valve prosthesis.
Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.
A method for determining a patient's likelihood of experiencing a thromboembolic event when receiving an implantable blood contacting medical device. The method includes extracting a sample of blood from the patient. The sample of blood is exposed to a metal, metal alloy, or ceramic in a test tube. The sample of the blood is agitated in the test tube. A thromboembolic marker for the sample in the test tube is measured. If the thromboembolic marker for the sample in the test tube is higher than a predetermined thromboembolic marker threshold, it is determined that the patient is likely to experience the thromboembolic event when receiving the blood contacting implantable medical device.
A method for processing patient data includes prompting a patient to complete a survey based on one or more of data received from an implantable medical device, a first time from an enrollment in a study related to the implantable medical device, a second time since a last survey, a medical event, or a detection of the patient in a geofenced area. The method may further include receiving input from the patient in response to the survey, and sending the input from the patient to a database.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
Delivery devices and methods for delivering a prosthetic heart valve. The delivery device includes an inner shaft assembly with a valve retainer, an outer shaft assembly, a handle assembly and an axial force adjustment assembly. The outer shaft assembly includes a capsule containing the prosthetic valve in a loaded state. The handle assembly is coupled to a proximal region of the outer shaft assembly. The axial force adjustment assembly connects a proximal section of the inner shaft assembly to the handle assembly, and is configured to selectively move the proximal section relative to the handle assembly. The axial force adjustment assembly can include an actuator member and a driver member. The driver member directly interfaces with the inner shaft assembly, and a force applied to the actuator member is transferred onto the proximal section via the driver member. A sensor for sensing tension and/or compression in the inner shaft assembly can be provided.
A61F 2/95 - Instruments specially adapted for placement or removal of stents or stent-grafts
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
68.
TRANSCATHETER DELIVERY SYSTEM AND METHOD WITH CONTROLLED EXPANSION AND CONTRACTION OF PROSTHETIC HEART VALVE
A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.
In some examples, a processor is configured determine whether efficacy of therapy delivered by a medical device to the patient may have changed and generate a notification based on the determination. For example, a processor may be configured to determine whether a bioelectrical brain signal indicative of activity of a brain of a patient includes a biomarker that indicates efficacy of therapy delivered by a medical device to the patient may have changed, and generate notification based on determining the bioelectrical brain signal includes the biomarker. In some examples, the processor modifies the therapy delivered to the patient prior to generating the notification.
This disclosure describes an implantable medical electrical lead and an ICD system utilizing the lead. The lead includes a lead body defining a proximal end and a distal portion, wherein at least a part of the distal portion of the lead body defines an undulating configuration. The lead includes a defibrillation electrode that includes a plurality of defibrillation electrode segments disposed along the undulating configuration spaced apart from one another by a distance. The lead also includes at least one electrode disposed between adjacent sections of the plurality of defibrillation sections. The at least one electrode is configured to deliver a pacing pulse to the heart and/or sense cardiac electrical activity of the heart.
Techniques are described for facilitating multi-party adjudication of cardiac episodes. An example system includes memory storing instructions and processing circuitry configured to execute those instructions to receive episode data of a cardiac episode from a medical device. The processing circuitry is configured to determine a region of the episode data based on input from a primary adjudicator and to display a notification to a secondary adjudicator. The processing circuitry is further configured to display the region of episode data to the secondary adjudicator and to receive and transmit input from the secondary adjudicator.
G16H 10/00 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
Some examples include a lithium-ion battery including an electrode assembly, a battery case, and an insulator. The electrode assembly includes a plurality of stacked electrodes. The battery case includes a cover and a housing. The housing includes a bottom, a perimeter side, and an open top. The cover is configured to extend across the open top. The cover and the housing form an interior enclosure to house the electrode assemble with the cover and the housing sealingly coupled at the lip. The insulator includes a body and a profiled portion. The body being generally planar and the profiled portion extending from the body at an angle. The body is disposed between the electrode assembly and the cover of the battery case. The profiled portion extends between the electrode assembly and the lip of the housing. The insulator is to provide a barrier between the electrode assembly and the sealed lip.
H01M 10/0585 - Construction or manufacture of accumulators having only flat construction elements, i.e. flat positive electrodes, flat negative electrodes and flat separators
H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodes; Lithium-ion batteries
H01M 50/474 - Spacing elements inside cells other than separators, membranes or diaphragms; Manufacturing processes thereof characterised by their position inside the cells
H01M 50/103 - Primary casings, jackets or wrappings of a single cell or a single battery characterised by their shape or physical structure prismatic or rectangular
In some examples, determining a heart failure status using a medical device comprising one or more sensors includes determining a first value of a heart beat variability metric of a patient while an activity state of a patient satisfies an inactivity criterion based on a signal received from the one or more sensors, and determining, within a predetermined period of time after further determining that the activity state of the patient no longer satisfies the inactivity criterion, a second value of the heart beat variability metric while the activity state of the patient no longer satisfies the inactivity criterion based on the signal. A difference between the first value of the heart beat variability metric and the second value of the heart beat variability metric may be determined and the heart failure status of the patient may be determined based on the difference.
A medical device processor is configured to receive a first cardiac electrical signal sensed from a first sensing electrode vector, receive a second cardiac electrical signal sensed from a second sensing electrode vector different than the first sensing electrode vector, and construct a third cardiac electrical signal from the first cardiac electrical signal and the second cardiac electrical signal. In some examples, the system determines sensed cardiac events according to at least one setting of a cardiac event sensing threshold control parameter from at least the third cardiac electrical signal and may determine at least one acceptable setting of a sensing control parameter based on the determined sensed cardiac events. The processor may generate an output representative of the determined sensed cardiac events.
A medical device system includes a memory; and processing circuitry in communication with the memory. The processing circuitry is configured to receive parametric data for a plurality of parameters of a patient, determine, based on the parametric data, an atrial fibrillation (AF) burden of the patient over a period of time, wherein the AF burden of the patient over the period of time includes a pattern of increased AF burden; output, for display by a user device, a request to identify whether the patient engaged in each patient behavior of a set of patient behaviors during the period of time; and determine, based on receiving a response indicating that the patient engaged in one or more patient behaviors of the set of patient behaviors, a suggestion to change at least a subset of the one or more patient behaviors to attenuate the pattern of increased AF burden.
An example system includes a memory; and processing circuitry coupled to the memory and configured to: receive electrocardiogram (ECG) data of a patient, wherein the ECG data is generated by one or more sensing devices of the patient based on physiological signals of the patient sensed by the one or more sensing devices; obtain a plurality of heartbeat intervals from the ECG data; sample a plurality of points for each respective heartbeat interval of the plurality of intervals; determine a slow-moving average for each sample point parameter of respective heartbeat intervals during a. first period of time; determine a fast-moving average for each sample point parameter of respective heartbeat intervals during a second period of time, determine a difference between the slow -moving average and the fast-moving average for each sample point parameter; and determine a risk level of a health event for the patient based on the determined differences.
A61B 5/0245 - Measuring pulse rate or heart rate using sensing means generating electric signals
A61B 5/0538 - Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
A61B 5/08 - Measuring devices for evaluating the respiratory organs
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using optical sensors, e.g. spectral photometrical oximeters
Methods, systems, and devices are configured delivering one or more sequences of different pulse trains to a patient. For example, a system includes processing circuitry configured to control stimulation circuitry to deliver a sequence of a plurality of trains of electrical stimulation pulses, wherein each train of the plurality of trains of electrical stimulation pulses comprises respective pulses at least partially defined by a unique parameter variation pattern of a plurality of parameter variation patterns, and control the stimulation circuitry to repeatedly deliver the sequence of the plurality of trains of electrical stimulation pulses.
Methods, systems, and devices are configured delivering one or more sequences of different pulse trains to a patient. For example, a system includes processing circuitry configured to control stimulation circuitry to deliver a sequence of a plurality of trains of electrical stimulation pulses, wherein each train of the plurality of trains of electrical stimulation pulses comprises respective pulses at least partially defined by a unique parameter variation pattern of a plurality of parameter variation patterns, and control the stimulation circuitry to repeatedly deliver the sequence of the plurality of trains of electrical stimulation pulses.
Systems, devices, and techniques are described for adjusting electrical stimulation based on detected ECAPs. In one example, a medical device includes processing circuitry configured to control stimulation circuitry to deliver a first electrical stimulation pulse and sensing circuitry to detect, after delivery of the first electrical stimulation pulse, an ECAP signal. The processing circuitry may be configured to determine a characteristic value of the ECAP signal, determine an ECAP differential value that indicates whether the characteristic value of the ECAP signal is one of greater than a selected ECAP characteristic value or less than the selected ECAP characteristic value, determine, based on the ECAP differential value, a gain value, determine, based on the gain value, a parameter value that at least partially defines a second electrical stimulation pulse, and control the stimulation circuitry to deliver the second electrical stimulation pulse according to the parameter value.
Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.
An adjustable rotational connector is configured to establish electrical communication between an implantable medical lead and a cable of an external testing device while allowing rotation of the implantable medical lead relative to the cable. The coupling includes a pin that is electrically conductive. An adjustable socket is positioned within the pin and is configured to receive lead connectors of different sizes. A bearing is configured to facilitate rotation of the pin relative to the cable. An actuatable element surrounds at least a portion of the adjustable socket. The actuatable element is configured to transition between a first and second position relative to the adjustable socket to allow the adjustable socket to receive and secure the lead connector of the implantable medical lead in the adjustable socket.
A61N 1/375 - Constructional arrangements, e.g. casings
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
H01R 13/62 - Means for facilitating engagement or disengagement of coupling parts or for holding them in engagement
F16L 37/12 - Couplings of the quick-acting type in which the connection between abutting or axially-overlapping ends is maintained by locking members using hooks, pawls, or other movable or insertable locking members
Systems, devices, methods, and techniques are described for using evoked compound action potential (ECAP) signals to monitor lead position and/or detect lead migration. An example system includes sensing circuitry configured to sense an ECAP signal, and processing circuitry. The processing circuitry controls the sensing circuitry to detect, after delivery of an electrical stimulation pulse, a current ECAP signal, and determines one or more characteristics of the current ECAP signal. The processing circuitry also compares the one or more characteristics of the current ECAP signal to corresponding one or more characteristics of a baseline ECAP signal, and determines, based on the comparison, a migration state of the electrodes delivering the electrical stimulation pulse. Additionally, the processing circuitry outputs, based on the migration state, an alert indicative of migration of the electrodes.
Subcutaneous implantation tools and methods of implanting a subcutaneous device using the same. The tool may include a tool body having a longitudinally extending recess having a distal opening and having a tunneler at a distal end of the tool body extending from the distal opening of the recess. The tool may include a plunger slidably fitting within at least a portion of the tool body recess. The recess may be configured to receive an implantable device and the tunneler preferably extends distally from the recess at a position laterally displaced from the device when the device is so located in the recess. Movement of the plunger distally within the recess advances the device distally out of the recess and alongside of and exterior to the tunneler.
A crimper for altering an implantable medical device from an uncompressed state to a compressed state. The crimper includes a plurality of crimper elements that define a crimper channel, each of the crimper elements including a non-planar surface that forms a portion of the crimper channel. Each non-planar surface is configured to apply non-uniform radial compression along a length of the implantable medical device during operation of the crimper when altering the implantable medical device from the uncompressed state to the compressed state. The crimper also includes handle configured to operate the crimper. Actuation of the handle decreases a volume of the crimper chamber to transition the implantable medical device from the uncompressed state to the compressed state.
A recapturable external LAA exclusion clip system includes a clip comprising first and second clip struts, at least one of the struts having a connector interface comprising a first portion of a lock, and a delivery device comprising a handle and an end effector. The handle comprises jaw and lock controls. The end effector is connected to the handle and comprises a clevis and first and second jaws. The jaws are connected to the clevis and operatively connected to the jaw control to actively articulate at least one of the jaws with respect to the other. At least one of the jaws has a connector comprising a second portion of the lock operatively connected to the lock control to removably lock with the first portion of the lock. The first and second portions of the lock have a locked state and are configured to unlock the locked state upon actuation of the lock control.
A61B 17/128 - Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
86.
MEDICAL DEVICE AND METHOD FOR TACHYARRYTHMIA DETECTION
A medical device is configured to determine time intervals between consecutive cardiac events sensed from a cardiac electrical signal, increase a value of a tachyarrhythmia interval count in response to each of the determine time intervals detected as a tachyarrhythmia interval. The device is further configured to detect normal sinus rhythm events and the decrease the value of the tachyarrhythmia interval count in response to a threshold number of detected normal sinus rhythm events.
This disclosure is directed to techniques for recording and recognizing physiological parameter patterns associated with symptoms. A medical device system includes a medical device including an accelerometer configured to collect an accelerometer signal that indicates one or more patient movements that occur during a cough. Additionally, the medical device system includes processing circuitry configured to: determine whether the accelerometer signal satisfies a set of criteria corresponding to a cough pattern comprising a smooth increase from a baseline, then a sharp decrease, a peak within the sharp decrease, then a gradual return to the baseline; and identify a cough based on the determination that the accelerometer signal satisfies the set of criteria.
Systems and methods for evaluating a subject having indications for receiving a prosthetic valve, such as a prosthetic mitral valve. Images of the subject's native annulus are obtained and assessed. A candidate prosthetic valve is selected based upon the assessment. An implant model of the candidate prosthetic valve is selected from a library of different implant models based upon the native annulus assessment. A virtual implant representation is generated by applying the selected implant model to the obtained images. An area of the neo-VOT of the virtual implant representation is reviewed. Whether or not the candidate prosthetic valve is appropriate for the subject is evaluated based upon the review.
A system comprises processing circuitry configured to receive parametric data for a plurality of parameters of a patient. The parametric data is generated by one or more sensing devices of the patient based on physiological signals of the patient sensed by the one or more sensing devices. The plurality of parameters comprise AF burden. The processing circuitry is configured to derive one or more features based on the parametric data for the plurality of parameters, wherein the one or more features comprise at least one AF burden pattern feature, apply the one or more features to a model, and determine a risk level of a health event for the patient based on the application of the one or more features to the model.
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
90.
MEDICAL DEVICE SYSTEM FOR CLASSIFICATION AND PREDICTION OF MEDICAL EVENTS USING TIME-BETWEEN-EVENT VALUES
A computing system including a memory, processing circuitry coupled to the memory, and communications circuitry. The processing circuitry is configured to determine a time-between-event (TBE) value for a first plurality of events detected by a computing device, determine a classification condition based on the determined TBE value and reference data stored in the memory, the reference data comprising information corresponding to prior detected events, based on a determined change in the TBE value, apply the classification condition to apply a to a plurality of detected events, wherein the plurality of detected events comprises the first plurality of events and the second plurality of events, and determine whether one or more of the plurality of detected events satisfies the classification condition. The communications circuitry is configured to communicate to another device via a network that the one or more of the plurality of detected events satisfies the classification condition.
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
91.
SYNCHRONIZATION OF ANTI-TACHYCARDIA PACING IN AN EXTRA-CARDIOVASCULAR IMPLANTABLE SYSTEM
An extra-cardiovascular implantable cardioverter defibrillator (ICD) system receives a cardiac electrical signal by an electrical sensing circuit via an extra-cardiovascular sensing electrode vector and senses cardiac events from the cardiac electrical signal. The ICD system detects tachycardia from the cardiac electrical signal and determines a tachycardia cycle length from the cardiac electrical signal. The ICD system determines an ATP interval based on the tachycardia cycle length and sets an extended ATP interval that is longer than the ATP interval. The ICD delivers ATP pulses to a patient's heart via an extra-cardiovascular pacing electrode vector different than the sensing electrode vector. The ATP pulses include a leading ATP pulse delivered at the extended ATP interval after a cardiac event is sensed from the cardiac electrical signal and a second ATP pulse delivered at the ATP interval following the leading ATP pulse.
Systems and methods of generating atrial electrical heterogeneity using electrical activity monitored using a plurality of external electrodes are described herein. The atrial electrical heterogeneity may include P-wave electrical heterogeneity. The atrial electrical heterogeneity generated from electrical activity monitored during atrial pacing therapy may be used to evaluate and adjust atrial pacing therapy. The atrial electrical heterogeneity generated from electrical activity monitored during intrinsic activation may be used to evaluate a patient's cardiac condition.
Medical devices that provide stimulation therapy that is adjusted based on sensed physiological signals compensate for drifting of those physiological signal values that can lead to stimulation control reaching limits and becoming less effective. The medical devices determine average values of the physiological signals and use those average values to compute adjusted physiological signal threshold(s). The adjusted threshold(s) bring the physiological signals closer to or within the threshold(s) to allow the stimulation adjustments to be made within stimulation limits that can influence the physiological signal to continue to be within the threshold(s) and provide more effective therapy.
A catheter includes a control handle and a catheter shaft coupled to the control handle and extending from the control handle. The catheter shaft has a proximal end coupled to the control handle and a distal end located opposite the proximal end. The catheter also includes a pull wire band coupled to the catheter shaft. At least a portion of the pull wire band is exposed to an environment outside of the catheter shaft. The catheter also includes a pull wire extending from the control handle and through the catheter shaft to the pull wire band.
An example receptacle connector for a catheter for performing pulsed field ablation (PFA). The receptacle connector includes a first side to receive electrical signals; a second side, opposite to the first side, to transfer the electrical signals to a plurality of electrodes; a surface on the first side; and a plurality of groups of pins extending from the surface. Each of the groups of pins includes at least one pin to electrically connect to a power source to receive the electrical signals, and an interlocking wall surrounding the at least one pin.
Subcutaneous implantation tools and methods of implanting a subcutaneous device using the same. The tool may include a tool body having a longitudinally extending recess having a distal opening and having a tunneler at a distal end of the tool body extending from the distal opening of the recess. The tool may include a plunger slidably fitting within at least a portion of the tool body recess. The recess may be configured to receive an implantable device and the tunneler preferably extends distally from the recess at a position laterally displaced from the device when the device is so located in the recess. Movement of the plunger distally within the recess advances the device distally out of the recess and alongside of and exterior to the tunneler.
A fixation device comprising a first elongated body extending distally from a distal end of an implantable medical device and a second elongated body extending distally from the distal end of the implantable medical device. The first elongated body comprises a helix having one or more coils, wherein a distal end of the helix is configured to penetrate into tissue of a patient. The second elongated body is configured to flexibly maintain contact with the tissue without penetrating the tissue, and wherein the second elongated body is disposed on the distal end at a separation angle away from an electrode disposed on the distal end of the implantable medical device, wherein the separation angle comprises an angle between the electrode and the second end of the second elongated body.
A fixation device comprising: a first elongated body configured to extend distally from a distal end of an implantable medical device, the first elongated body comprising: a distal end configured to penetrate into tissue of a patient; and a helix having one or more coils; and an anti-rotation feature defined by the one or more coils, the anti-rotation feature configured to resist rotation of the helix within the tissue, wherein the anti-rotation feature comprises a varying pitch of the helix, the varying pitch resulting at least in part from an undulating configuration of the one or more coils of the helix.
Techniques for classifying a health condition of a patient are described. An example technique may include utilizing a probability model that uses various diagnostic states of physiological parameters, which may include fluid retention and temperature, to determine a classification of a health condition of the patient. The probability model may determine a probability score indicating a likelihood of the classification of the health condition being correct. The probability model may output the classification of the health condition and the probability score.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
100.
INTRA-LUMINAL MEDICAL DEVICE WITH EVOKED BIOPOTENTIAL SENSING CAPABILITY
Sensing an evoked response to electrical stimulation of target tissue of a patient in conjunction with an intra-luminal electrode. The intra-luminal electrode may be implanted in a blood vessel or similar lumen proximal to the target tissue and the sensed signals and/or delivered stimulation may pass through the blood vessel, or other lumen, walls. In some examples the evoked response may be an evoked compound action potential (ECAP), which may also be evoked resonant neural activity (ERNA). The electrical stimulation may elicit a measurable response indicative of a thought pattern or neural state that would otherwise be undetectable using a non-evoked biopotential.