Labrador Diagnostics LLC

United States of America

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G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing 6
G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals 6
G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor 5
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons 4
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices 4
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Status
Pending 4
Registered / In Force 16
Found results for  patents

1.

NUCLEIC ACID AMPLIFICATION

      
Document Number 02903874
Status In Force
Filing Date 2014-03-15
Open to Public Date 2014-09-18
Grant Date 2024-02-20
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Belhocine, Kamila
  • Lee, Josephine
  • Patel, Pranav
  • Richardson, Aaron
  • Tabakman, Scott

Abstract

Methods and compositions for the amplification of nucleic acids are disclosed. Amplification methods provided herein may be performed under isothermal conditions. Methods and compositions may include reagents such as nucleic acid polymerases, ligases, and primers.

IPC Classes  ?

  • C12Q 1/6844 - Nucleic acid amplification reactions
  • C12Q 1/6862 - Ligase chain reaction [LCR]
  • C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
  • C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides

2.

SYSTEMS AND METHODS FOR SAMPLE USE MAXIMIZATION

      
Document Number 02825196
Status In Force
Filing Date 2012-01-20
Open to Public Date 2012-07-26
Grant Date 2021-01-05
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Gibbons, Ian
  • Nugent, Tony
  • Delacruz, Anthony
  • Young, Daniel
  • Holmes, Elizabeth
  • Drake, Andrew
  • Kemp, Timothy Michael
  • Balwani, Sunny
  • Pangarkar, Chinmay

Abstract

The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.

IPC Classes  ?

  • G01N 21/59 - Transmissivity
  • B04B 7/00 - Elements of centrifuges
  • C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
  • G01N 1/28 - Preparing specimens for investigation
  • G01N 21/27 - Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
  • G01N 21/63 - Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
  • G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
  • G01N 33/483 - Physical analysis of biological material
  • G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
  • G01N 37/00 - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES - Details not covered by any other group of this subclass

3.

INTEGRATED HEALTH DATA CAPTURE AND ANALYSIS SYSTEM

      
Document Number 02778270
Status In Force
Filing Date 2010-10-18
Open to Public Date 2011-04-28
Grant Date 2021-01-05
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Holmes, Elizabeth A.
  • Young, Daniel L.
  • Michelson, Seth G.
  • Gibbons, Ian

Abstract

The present invention provides an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions. The system can be used to monitor infectious and chronic diseases. When faced with outbreak of an infectious disease agent, e.g., influenza virus, the system can identify active cases through pro-active sampling in high risk locations, such as schools or crowded commercial areas. The system can notify appropriate entities, e.g., local, regional and national governments, when an event is detected, thereby allowing for proactive management of a possible outbreak. The system also predicts the best response for deployment of scarce resources.

IPC Classes  ?

  • G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
  • G16H 40/00 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
  • G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
  • G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
  • G16H 50/80 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for detecting, monitoring or modelling epidemics or pandemics, e.g. flu

4.

INTEGRATED HEALTH DATA CAPTURE AND ANALYSIS SYSTEM

      
Document Number 03081708
Status In Force
Filing Date 2010-10-18
Open to Public Date 2011-04-28
Grant Date 2023-10-03
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Gibbons, Ian
  • Holmes, Elizabeth A.
  • Michelson, Seth G.
  • Young, Daniel L.

Abstract

The present invention provides an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions. The system can be used to monitor infectious and chronic diseases. When faced with outbreak of an infectious disease agent, e.g., influenza virus, the system can identify active cases through pro-active sampling in high risk locations, such as schools or crowded commercial areas. The system can notify appropriate entities, e.g., local, regional and national governments, when an event is detected, thereby allowing for proactive management of a possible outbreak. The system also predicts the best response for deployment of scarce resources.

IPC Classes  ?

  • G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 33/569 - Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • G16B 50/00 - ICT programming tools or database systems specially adapted for bioinformatics

5.

MODULAR POINT-OF-CARE DEVICES AND USES THEREOF

      
Document Number 03042430
Status In Force
Filing Date 2008-10-02
Open to Public Date 2009-04-09
Grant Date 2022-10-11
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Burd, Tammy
  • Gibbons, Ian
  • Holmes, Elizabeth A.
  • Frenzel, Gary
  • Nugent, Anthony Joseph

Abstract

The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

IPC Classes  ?

  • G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
  • G01N 1/38 - Diluting, dispersing or mixing samples
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/84 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
  • G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

6.

MODULAR POINT-OF-CARE DEVICES AND USES THEREOF

      
Document Number 03170924
Status Pending
Filing Date 2008-10-02
Open to Public Date 2009-04-09
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Burd, Tammy
  • Gibbons, Ian
  • Holmes, Elizabeth A.
  • Frenzel, Gary
  • Nugent, Anthony Joseph

Abstract

The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

IPC Classes  ?

  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G01N 1/28 - Preparing specimens for investigation
  • G01N 1/38 - Diluting, dispersing or mixing samples
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
  • G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

7.

MODULAR POINT-OF-CARE DEVICES AND USES THEREOF

      
Document Number 02701794
Status In Force
Filing Date 2008-10-02
Open to Public Date 2009-04-09
Grant Date 2017-10-31
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Burd, Tammy
  • Gibbons, Ian
  • Holmes, Elizabeth A.
  • Frenzel, Gary
  • Nugent, Anthony Joseph

Abstract

The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

IPC Classes  ?

  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
  • C40B 30/00 - Methods of screening libraries
  • C40B 60/00 - Apparatus specially adapted for use in combinatorial chemistry or with libraries
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor

8.

MODULAR POINT-OF-CARE DEVICES AND USES THEREOF

      
Document Number 02934220
Status In Force
Filing Date 2008-10-02
Open to Public Date 2009-04-09
Grant Date 2019-11-05
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Burd, Tammy
  • Gibbons, Ian
  • Holmes, Elizabeth A.
  • Frenzel, Gary
  • Nugent, Anthony Joseph

Abstract

The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.

IPC Classes  ?

  • G01F 22/00 - Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for
  • G01N 1/28 - Preparing specimens for investigation

9.

MODULAR POINT-OF-CARE DEVICES AND USES THEREOF

      
Document Number 03138078
Status In Force
Filing Date 2008-10-02
Open to Public Date 2009-04-09
Grant Date 2024-02-13
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Burd, Tammy
  • Gibbons Ian
  • Holmes, Elizabeth A.
  • Frenzel, Gary
  • Nugent, Anthony Joseph

Abstract

A system and a method for detecting an analyte in a biological sample is provided. The system comprises a cartridge that has a sample well to receive the biological sample, a plurality of reagent wells for storing a reagent, a pipette tip with an opening and an interior surface, and a reader assembly for receiving the cartridge. An antibody for binding to the analyte is immobilized on the interior surface of the pipette tip. The reader assembly has an automated fluid transfer device that engages the pipette tip and moves it into communication with the sample well and one or more of the reagent wells. The reader assembly also has a detection assembly for detecting an optical signal indicative of a presence of the bound analyte.

IPC Classes  ?

  • G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

10.

REDUCING OPTICAL INTERFERENCE IN A FLUIDIC DEVICE

      
Document Number 03057690
Status In Force
Filing Date 2007-10-10
Open to Public Date 2008-05-29
Grant Date 2023-08-22
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Gibbons, Ian
  • O'Connell, Michael

Abstract

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.

IPC Classes  ?

  • B81C 3/00 - Assembling of devices or systems from individually processed components
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

11.

REDUCING OPTICAL INTERFERENCE IN A FLUIDIC DEVICE

      
Document Number 02666338
Status In Force
Filing Date 2007-10-10
Open to Public Date 2008-05-29
Grant Date 2017-08-29
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Gibbons, Ian
  • O'Connell, Michael

Abstract

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.

IPC Classes  ?

  • G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
  • G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
  • G01N 21/76 - Chemiluminescence; Bioluminescence
  • G01N 33/52 - Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor

12.

REDUCING OPTICAL INTERFERENCE IN A FLUIDIC DEVICE

      
Document Number 03203331
Status Pending
Filing Date 2007-10-10
Open to Public Date 2008-05-29
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Gibbons, Ian
  • O'Connell, Michael

Abstract

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.

IPC Classes  ?

  • G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
  • G01N 1/10 - Devices for withdrawing samples in the liquid or fluent state
  • G01N 21/15 - Preventing contamination of the components of the optical system or obstruction of the light path

13.

REDUCING OPTICAL INTERFERENCE IN A FLUIDIC DEVICE

      
Document Number 02972774
Status In Force
Filing Date 2007-10-10
Open to Public Date 2008-05-29
Grant Date 2019-11-26
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Gibbons, Ian
  • O'Connell, Michael

Abstract

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.

IPC Classes  ?

  • B81C 3/00 - Assembling of devices or systems from individually processed components
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor

14.

REAL-TIME DETECTION OF INFLUENZA VIRUS

      
Document Number 02650455
Status In Force
Filing Date 2007-05-10
Open to Public Date 2007-11-22
Grant Date 2018-01-02
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Holmes, Elizabeth A.
  • Gibbons, Ian

Abstract

The present invention provides system and methods for detecting an analyte indicative of an influenza viral infection in a sample of bodily fluid. The present invention also provides for systems and method for detection a plurality of analytes, at least two of which are indicative of an influenza viral infection in a sample of bodily fluid.

IPC Classes  ?

  • G01N 33/569 - Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • G01N 33/566 - Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagent
  • G01N 33/573 - Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes

15.

REAL-TIME DETECTION OF INFLUENZA VIRUS

      
Document Number 02977365
Status In Force
Filing Date 2007-05-10
Open to Public Date 2007-11-22
Grant Date 2021-01-26
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Holmes, Elizabeth A.
  • Gibbons, Ian

Abstract

The present invention provides system and methods for detecting an analyte indicative of an influenza viral infection in a sample of bodily fluid. The present invention also provides for systems and method for detection a plurality of analytes, at least two of which are indicative of an influenza viral infection in a sample of bodily fluid.

IPC Classes  ?

  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 33/569 - Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses

16.

POINT-OF-CARE FLUIDIC SYSTEMS AND USES THEREOF

      
Document Number 03209322
Status Pending
Filing Date 2006-03-24
Open to Public Date 2006-11-16
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Holmes, Elizabeth A.
  • Roy, Shaunak
  • Howard, John
  • Wang, Chengwang
  • Gibbons, Ian
  • Kemp, Tim
  • Todd, Chris
  • Oral, Ron
  • Zeng, Shulin
  • Fenton, Jeff
  • Qi, Shize Daniel

Abstract

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

IPC Classes  ?

  • A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
  • G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
  • G16H 40/60 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
  • A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
  • A61B 5/1459 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
  • A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value using chemical or electrochemical methods, e.g. by polarographic means
  • A61B 5/15 - Devices for taking samples of blood
  • C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

17.

POINT-OF-CARE FLUIDIC SYSTEMS AND USES THEREOF

      
Document Number 02610294
Status In Force
Filing Date 2006-03-24
Open to Public Date 2006-11-16
Grant Date 2023-10-03
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Holmes, Elizabeth A.
  • Roy, Shaunak
  • Howard, John
  • Wang, Chengwang
  • Gibbons, Ian
  • Kemp, Tim
  • Todd, Chris
  • Oral, Ron
  • Zeng, Shulin
  • Fenton, Jeff
  • Qi, Shize Daniel

Abstract

This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

18.

MEDICAL DEVICE FOR ANALYTE MONITORING AND DRUG DELIVERY

      
Document Number 02538038
Status In Force
Filing Date 2004-09-10
Open to Public Date 2005-03-24
Grant Date 2015-10-27
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Holmes, Elizabeth A.
  • Roy, Shaunak
  • Howard, John
  • Wang, Chengwang

Abstract

The invention relates to an ingestible, implantable or wearable medical device comprising a microarray having a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and a microchip comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; and an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and a therapeutic agent releasing device. The medical device is capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a microchannel through which the sample flows and is in fluid communication with the at least one microneedle, and an interface device.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
  • A61B 5/15 - Devices for taking samples of blood
  • A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
  • B01J 19/00 - Chemical, physical or physico-chemical processes in general; Their relevant apparatus
  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

19.

MEDICAL DEVICE FOR ANALYTE MONITORING AND DRUG DELIVERY

      
Document Number 02852974
Status In Force
Filing Date 2004-09-10
Open to Public Date 2005-03-24
Grant Date 2017-06-27
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Holmes, Elizabeth A.
  • Roy, Shaunak
  • Howard, John
  • Wang, Chengwang

Abstract

The invention relates to an ingestible, implantable or wearable medical device comprising a microarray having a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent; and a microchip comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; and an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and a therapeutic agent releasing device. The medical device is capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a microchannel through which the sample flows and is in fluid communication with the at least one microneedle, and an interface device.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
  • A61B 5/07 - Endoradiosondes
  • A61B 5/157 - Devices for taking samples of blood characterised by integrated means for measuring characteristics of blood
  • A61J 3/00 - Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/66 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
  • G01N 33/74 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones

20.

MEDICAL DEVICE FOR ANALYTE MONITORING AND DRUG DELIVERY

      
Document Number 02896407
Status Pending
Filing Date 2004-09-10
Open to Public Date 2005-03-24
Owner LABRADOR DIAGNOSTICS LLC (USA)
Inventor
  • Holmes, Elizabeth A.
  • Roy, Shaunak
  • Howard, John
  • Wang, Chengwang

Abstract

An implantable medical device for detecting an analyte in a bodily tissue, comprising a microarray comprising a bioactive agent for interaction with the analyte. The microarray consists of a plurality of sites on a surface with the bioactive agent for interaction with the analyte and a plurality of channels for a bodily fluid comprising the analyte to flow into the medical device and contact the bioactive agent. The implantable medical device also comprises a a scanning device for detecting the interaction and an interface device for wirelessly transmitting data of the interaction.

IPC Classes  ?

  • A61B 5/15 - Devices for taking samples of blood
  • A61B 5/151 - Devices for taking samples of blood specially adapted for taking samples of capillary blood, e.g. by lancets
  • A61B 5/157 - Devices for taking samples of blood characterised by integrated means for measuring characteristics of blood
  • A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters