A 11 is used for the enzymatic catalysis. The invention makes accessible new substrates in the enzymatic production of L-glufosinate and its phosphoesters.
11 (aminocarboxypropyltransferase, EC 2.5.1) are used for the enzymatic catalysis. The invention makes accessible new substrates in the enzymatic production of L-glufosinate and its phosphoesters.
The invention relates to a method for the computer-implemented control of a goods delivery from a goods sender to a goods recipient using an access-restricted DLT system (182). The DLT system (182) comprises a first DLT node allocated to the goods recipient and a second DLT node allocated to the goods sender. Furthermore, the DLT system (182) provides at least one smart contract with program instructions for entering and checking delivery orders (190), order confirmations (191) and goods issue logs during goods deliveries from the goods sender to the goods recipient and for validating the goods delivery. The method comprises, for example, initiating the goods delivery in the DLT system (182), for example logging the goods delivery in the DLT system (182) and/or for example validating the goods delivery in the DLT system (182).
H04L 9/32 - Arrangements for secret or secure communications; Network security protocols including means for verifying the identity or authority of a user of the system
G06Q 10/0875 - Itemisation or classification of parts, supplies or services, e.g. bill of materials
The present invention relates to the electrochemical production of hydrogen and lithium hydroxide from Li+-containing water using a LiSICon membrane. The problem addressed by the present invention is that of specifying a process which is operable economically even on an industrial scale. The process shall especially exhibit a high energy efficiency and achieve a long service life of the membrane even when the employed feed contains impurities harmful to LiSICon materials. A particular aspect of the process is that the cell simultaneously separates off the lithium via the membrane and effects electrolysis of water. An essential aspect of the process is that the electrochemical process is performed in a basic environment, more precisely at pH 9 to 13. The pH is adjusted by addition of a basic compound to the feed.
C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
C25B 11/00 - Electrodes; Manufacture thereof not otherwise provided for
C02F 103/16 - Nature of the water, waste water, sewage or sludge to be treated from metallurgical processes, i.e. from the production, refining or treatment of metals, e.g. galvanic wastes
5.
ELECTROCHEMICAL PRODUCTION OF HYDROGEN AND LITHIUM HYDROXIDE UNDER DEFINED FLOW CONDITIONS
The problem addressed by the present invention is that of specifying a process for electrochemical production of LiOH from Li+-containing water using an electrochemical cell having a LiSICon membrane which is operable economically even on an industrial scale. The process shall especially have a high energy efficiency and achieve a long service life of the membrane even when the employed feed contains impurities damaging to LiSICon materials. The problem is solved by adjusting the flow conditions in the anodic compartment of the electrochemical cell such that the anolyte flows along the membrane at a certain minimum flow rate.
C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
The problem addressed by the present invention is that of specifying a process for producing lithium hydroxide which is very energy efficient. The process shall especially operate without consumption of thermal energy. The process shall be able to handle, as raw material, Li-containing waters generated during digestion of spent lithium-ion batteries. The LiOH produced by the process shall have a high purity sufficient for direct manufacture of new LIB. The process shall achieve a high throughput and have small footprint in order that it can be combined with existing processes for workup of used LIB/for production of new LIB to form a closed, continuous production loop. The process according to the invention is an electrolytic membrane process operating with a LiSICon membrane. It is a special aspect of the process that the electrolysis is operated up to the precipitation limit of the lithium hydroxide.
C02F 1/469 - Treatment of water, waste water, or sewage by electrochemical methods by electrochemical separation, e.g. by electro-osmosis, electrodialysis, electrophoresis
C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
C25B 11/00 - Electrodes; Manufacture thereof not otherwise provided for
C02F 103/16 - Nature of the water, waste water, sewage or sludge to be treated from metallurgical processes, i.e. from the production, refining or treatment of metals, e.g. galvanic wastes
7.
CATALYST FOR EPOXIDATION REACTIONS AND PREPARATION THEREOF
The present invention relates to processes for preparing propylene oxide, comprising reaction of propene with ethylbenzene hydroperoxide in the presence of a catalyst, as well as to catalysts employed in such processes and to methods for their manufacture. The catalysts of the invention are prepared in a process comprising sol-gel-synthesis of catalyst hydrogel-precursor, drying of catalyst hydrogel precursor, calcining of dried catalyst hydrogel-precursor, and optionally hydrophobizing the calcined catalyst hydrogel-precursor. The catalysts of the invention comprise amorphous titanium doped silica comprising pentahedrally coordinated titanium species.
B01J 35/10 - Solids characterised by their surface properties or porosity
C07D 301/19 - Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic hydroperoxides
C07D 303/04 - Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
Present invention relates to an apparatus (0) for producing nanocarriers and/or nanoformulation and a process for producing a nanocarrier and/or a nanoformulation by means of this apparatus (0). According to inventive preparation, a first liquid phase (A) and the second liquid phase (B) are mixed first to give the primary mixture (A+B) by means of a static mixer (4). In a subsequence mixing step primary mixture (A+B) is diluted with a third liquid (C). An important aspect of apparatus (0) is the arrangement of the static mixer (4) inside a linear pipe (7) conducting third liquid phase (C). Thus, the primary mixture (A+B) exiting the mixer (4) is instantaneously diluted with (C) to give secondary mixture (A+B+C). The volume flow of the third mixture (C) is chosen larger than the volume flow of the primary mixture (A+B). By these measures, nanocarriers with improved morphology and homogeneity are produced. Encapsulation efficiency was enhanced as well.
B01F 23/45 - Mixing liquids with liquids; Emulsifying using flow mixing
B01F 25/313 - Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced in the centre of the conduit
B01F 25/4314 - Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor with helical baffles
B01F 25/53 - Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle in which the mixture is discharged from and reintroduced into a receptacle through a recirculation tube, into which an additional component is introduced
B33Y 80/00 - Products made by additive manufacturing
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS (Germany)
Inventor
Nagarajan, Sanjanaa
Roy, Suki
Böhl, Florian
Whelan, Rose
Huang, Lingzhi
Wong, Kit Yeng
Chan, Sarah
Franke, Daniel
Lyko, Frank
Venkatesh, Geetha
Raddatz, Günter
Tönges, Sina
Pfefferle, Walter
Wessel, Rainer
Abstract
The present invention is related to a DNA methylation-based array comprising at least: a first plurality of distinct locations, each location having at least one probe molecule comprising a nucleic acid sequence complementary to a CpG site from a first plurality of CpG sites of a first animal species; and a second plurality of distinct locations, each location having at least one probe molecule comprising a nucleic acid sequence complementary to a CpG site from a second plurality of CpG sites of a second animal species, wherein the first and second animal species are each independently selected from the group consisting of virus, mammals, birds and aquatic animals, and - the mammal is at least one livestock or animal cell line; - the bird is at least one poultry; and - the aquatic animal is at least one crustacean, cephalopod or fish, and wherein the first plurality of CpG sites comprises at least 1000 CpG sites of the first animal species; and the second plurality of CpG sites comprises at least 1000 CpG sites of the second animal species.
The present invention is related to a method of detecting DNA methylation and/or determining a test methylation profile from genomic material contained in a biological sample obtained from a test animal-derived product, the method comprises the step of: - contacting a genomic material sample from the test animal-derived product with a DNA methylation array specific for species of the test animal, wherein the test animal is a monogastric livestock.
C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
11.
IDENTIFYING BREEDING CONDITIONS OF LIVESTOCK USING EPIGENETICS
The present invention relates to a method of certifying a test animal-derived product sample, the method comprising the steps of: (a) determining a test methylation profile of one or more pre-selected methylation sites within the genomic material obtained from the test animal derived product sample; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile obtained from a control animal of the same biological taxon of the test animal from which the product sample is derived from, where the control animal is bred under a known distinct type of animal husbandry; wherein a significant similarity in the test methylation profile of (a) compared to the reference methylation profile from the control animal, is indicative of the test animal having been bred under the same distinct type of animal husbandry as the control animal and the test animal-derived product is certified so; wherein a difference in the test methylation profile of (a) compared to the reference methylation profile of the control animal, is indicative of the test animal having been bred under another distinct type of animal husbandry as the control animal; and wherein the pre-selected methylation sites are CpG sites selected from genes or regions of genomic DNA from the control and test animal that show the highest degree of methylation variation during the training of the method; and wherein the test methylation profile has significant similarity to the reference methylation profile when the test methylation profile overlaps with the reference methylation profile that is defined by multiple training samples using Principal Component analysis and/ or Multi-Dimensional Scaling; and wherein the methylation profiles are determined using at least one method selected from the group consisting of PCR, methylation- specific PCR, real-time methylation-specific PCR, PCR assay using a methylation DNA- specific binding protein, quantitative PCR, a DNA chip-based assay, pyrosequencing, bisulfate pyrosequencing, Methylated DNA immunoprecipitation-sequencing and combinations thereof; andwherein the test animal is selected from livestock or poultry.
The present invention relates to a composition comprising: - an isolated endophyte, wherein the endophyte is a strain of Rhizobium metallidurans, and - an adjuvant and wherein the Rhizobium metallidurans strain has Accession Number DSM34351.
The present invention relates to a composition comprising: - an isolated endophyte, wherein the endophyte is a strain of Paenibacillus xylanexedens, and - an adjuvant, wherein the strain of Paenibacillus xylanexedens has Accession Number DSM 34353.
The present invention is related to a method of determining suitability of at least one Chinese Hamster Ovary (CHO) test cell line for optimal heterologous protein production, the method comprising: (a) determining a test methylation profile from genomic material obtained from the CHO test cell line; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile, wherein the reference methylation profile comprises the methylation status of more than one CpG site from at least one CHO reference cell line that displays at least one phenotype of interest for optimal heterologous protein production, wherein a significant similarity in the test methylation profile of (a) compared to the reference methylation profile, is indicative of the CHO test cell line being suitable for optimal heterologous protein production and wherein the test methylation profile and reference methylation profile are from CpG sites from the CHO cell genome and are determined using DNA methylation- bead-based array.
C12Q 1/6881 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
The invention relates to a composition for producing polyurethane, preferably PU foam, particularly preferably rigid PU foam, comprising a polyisocyanate component, a polyol component, optionally a blowing agent, at least one solid filler, and optionally at least one catalyst that catalyzes the formation of a urethane or isocyanurate bond, the composition containing at least one surfactant based on a quarternary ammonium compound.
The present invention is directed to polyalkyl(meth)acrylate-based polymers comprising defined amounts of long-chain alkyl (meth)acrylates, their preparation, lubricant compositions comprising such polymers and their use to improve the thickening efficiency and low temperature performance of lubricant compositions, especially of engine oil (EO) compositions.
A method for preparing flexible slabstock polyurethane foam comprising contacting at least one polyisocyanate with at least one polyol in the presence of at least one polyurethane additive selected from the group consisting of a blowing agent, a cell stabilizer, and a crosslinker, and a catalyst composition comprising at least one compound represented by formula (I): (I), wherein R1, R2, R3, R4, and R513266 alkenyl linear or branched.
C07C 213/02 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
C07C 213/08 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
20.
A FABRIC SOFTENER ACTIVE COMPOSITION FOR PREPARING A TRANSPARENT FABRIC SOFTENER COMPOSITION
A fabric softener active composition, comprising, based on the total weight of the fabric softener active composition: A) 20 to 80 wt. -%of at least one solubilizer, which is selected from the group consisting of mono long-chain-alkyl amido quaternary ammonium salts, alkoxylated mono long-chain-alkyl quaternary ammonium salts, and alkoxylated mono long-chain-alkyl amido quaternary ammonium salts, and B) 10 to 50 wt. -%of at least one softening ingredient, which is selected from the group consisting of di-long-chain-alkyl quaternary ammonium salts, di-long-chain-alkyl ester quaternary ammonium salts, di-long-chain-alkyl imidazoline quaternary ammonium salts, di-long-chain-alkyl amido quaternary ammonium salts, ethoxylated di-long-chain-alkyl ester quaternary ammonium salts, ethoxylated tri-long-chain-alkyl ester quaternary ammonium salts and ethoxylated di-long-chain-alkyl amido quaternary ammonium salts. A transparent fabric softener composition and a fabric softener product are also provided.
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS (Germany)
Inventor
Nagarajan, Sanjanaa
Roy, Suki
Whelan, Rose
Böhl, Florian
Lyko, Frank
Tönges, Sina
Abstract
The present invention relates to a method of certifying a test animal-derived product sample, the method comprising the steps of: (a) determining a test methylation profile of one or more pre-selected methylation sites within the genomic material obtained from the test animal derived product sample; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile obtained from a control animal of the same biological taxon of the test animal from which the product sample is derived from, where the control animal is not slaughtered by a single cut across the throat severing both carotid arteries, both jugular veins, both vagus nerves, trachea and/or esophagus and/or the control animal is not bled to death wherein a difference in the test methylation profile of (a) compared to the reference methylation profile from the control animal, is indicative of the test animal having been slaughtered by a single cut across the throat severing both carotid arteries, both jugular veins, both vagus nerves, trachea and/or oesophagus and/or of the test animal having been bled to death and the test animal-derived product is certified so, and wherein the pre-selected methylation sites are CpG sites selected from genes or regions of genomic DNA from the control and test animal that shows the highest degree of methylation variation during the training of the method.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
22.
A FABRIC SOFTENER ACTIVE COMPOSITION FOR PREPARING A TRANSPARENT FABRIC SOFTENER COMPOSITION
A fabric softener active composition, comprising, based on the total weight of the fabric softener active composition: A) 20 to 80wt. %of at least one solubilizer, which is selected from the group consisting of mono long-chain-alkyl quaternary ammonium salts, mono long-chain-alkyl amido quaternary ammonium salts, alkoxylated mono long-chain-alkyl quaternary ammonium salts, and alkoxylated mono long-chain-alkyl amido quaternary ammonium salts, and B) 10 to 50wt. %of at least one softening ingredient, which is selected from the group consisting of di-long-chain-alkyl quaternary ammonium salts, di-long-chain-alkyl ester quaternary ammonium salts, di-long-chain-alkyl imidazoline quaternary ammonium salts, di-long-chain-alkyl amido quaternary ammonium salts, ethoxylated di-long-chain-alkyl ester quaternary ammonium salts, ethoxylated tri-long-chain-alkyl ester quaternary ammonium salts and ethoxylated di-long-chain-alkyl amido quaternary ammonium salts. A transparent fabric softener composition and a fabric softener product are also provided.
The invention relates to a process for producing zirconium phosphate by means of flame spray pyrolysis, zirconium phosphate obtainable by this process and the use thereof in batteries especially to encapsulate lithium mixed oxide particles.
DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS (Germany)
Inventor
Lingenberg, Annika
Tönges, Sina
Lyko, Frank
Whelan, Rose
Böhl, Florian
Roy, Suki
Nagarajan, Sanjanaa
Giatsis, Christos
Pelzer, Stefan
Abstract
The present invention is related to a method of determining if a test animal and/or a test animal from which a product is derived has been treated and/or is currently undergoing treatment with at least one antibiotic and/or veterinary chemical, the method comprising: (a) determining a test methylation profile from the genomic material contained in a biological sample obtained from the test animal and/or the animal-derived product; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile obtained from a control animal of the same biological taxon of the test animal, where the control animal was not treated and/or is not currently undergoing treatment with at least one antibiotic and/or veterinary chemical, wherein a difference in the test methylation profile of (a) compared to the reference methylation profile from the control animal, is indicative of the test animal having been treated and/or is currently undergoing treatment with at least one antibiotic and/or veterinary chemical; and wherein the test animal is an aquatic animal; and the veterinary chemical is an anti-parasitic, an anti- viral, a feed additive, a water additive, a disinfectant, glutaraldehyde, and/ or formalin used in aquaculture.
C12Q 1/6809 - Methods for determination or identification of nucleic acids involving differential detection
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
25.
DETECTING ANTIBIOTIC AND/OR CHEMICAL USE IN ANIMALS USING EPIGENETIC MEANS
The present invention is related to a method of determining if a test animal and/or a test animal from which a product is derived has been treated and/or is currently undergoing treatment with at least one antibiotic and/or veterinary chemical, the method comprising: (a) determining a test methylation profile from the genomic material contained in a biological sample obtained from the test animal and/or the animal-derived product; and (b) comparing the test methylation profile obtained from (a) with a reference methylation profile obtained from a control animal of the same biological taxon of the test animal, where the control animal was not treated and/or is not currently undergoing treatment with at least one antibiotic and/or veterinary chemical, wherein a difference in the test methylation profile of (a) compared to the reference methylation profile from the control animal, is indicative of the test animal having been treated and/or is currently undergoing treatment with at least one antibiotic and/or veterinary chemical; and wherein the test animal is a terrestrial animal and wherein the veterinary chemical is an anti-parasitic, an anti-viral, a feed additive, a water additive, a disinfectant, glutaraldehyde, and/ or formalin.
C12Q 1/6809 - Methods for determination or identification of nucleic acids involving differential detection
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
26.
SILICONE URETHANE (METH)ACRYLATES AND THEIR USE IN COATING COMPOSITIONS
The invention relates to compositions comprising silicone urethane (meth)acrylates having at least three (meth)acrylate groups and not more urethane groups than (meth)acrylate groups, methods for preparing said compositions, as well as release coatings, protective films, and protective coatings obtainable by curing said compositions.
C08G 18/75 - Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic
C08L 75/16 - Polyurethanes having carbon-to-carbon unsaturated bonds having terminal carbon-to-carbon unsaturated bonds
C09D 175/16 - Polyurethanes having carbon-to-carbon unsaturated bonds having terminal carbon-to-carbon unsaturated bonds
C08F 283/12 - Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass on to polysiloxanes
C09D 4/00 - Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond
27.
COMPOSITIONS COMPRISING SELF TANNING AGENTS AND CERTAIN SPHINGOLIPIDS AND/OR CERTAIN SPHINGOID BASES
C07C 233/18 - Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
A61K 31/164 - Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
The present invention relates to a computer-implemented method for verifying the authenticity of a product, a product comprising an identification substance for verifying the authenticity of the product, the use of an identification substance according to the present invention or of a product according to the present invention for verifying the authenticity of a product by means of EPR spectrometry, and a system for verifying the authenticity of a product, wherein the system comprises i) a processing unit adapted for carrying out the method according to the present invention, and ii) comprises or has access to a database with a library of EPR spectra of one, more, or a multitude of identification substances.
G01N 24/10 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using electron paramagnetic resonance
G01R 33/60 - Arrangements or instruments for measuring magnetic variables involving magnetic resonance using electron paramagnetic resonance
C08F 126/06 - Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
C08F 226/06 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
Recombinant bacterial collagen-like protein with an amino acid sequence that is at least ≥ 60% identical to the amino acid sequence of SEQ ID NO:1 characterized in that the amino acid sequence comprises a deletion of at least 38 amino acids at the N-terminus of the amino acid sequence of SEQ ID NO:1 and that the recombinant collagen-like protein is functionalized with ethylenic unsaturated groups.
C07K 14/34 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
22 (carbonating) at a temperature of 15-60°C to precipitate a mixture containing methionine and potassium hydrogencarbonate as precipitate which contains on average not more than 6.5% by weight of met-met and separating said precipitate from the mother liquor.
C07C 319/20 - Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
C07C 323/58 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
C07K 5/062 - Dipeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
32.
PRESSURE ENHANCED (TRANS)ESTERIFICATION OF (METH)ACRYLATE COMPOUNDS
The present invention discloses a method for pressure enhanced (trans)esterification of (meth)acrylic esters. The method can prepare an alkyl (meth)acrylate product by a (trans)esterification reaction of a reaction mixture. The reaction mixture comprises a (meth)acrylate starting material and a first alcohol which are converted by the (trans)esterification reaction in the presence of a catalyst into the alkyl (meth )acry late product and a side product. The (trans)esterification reaction is carried out in a reactor system. The reactor system comprises a reboiler, a reaction chamber comprising the reaction mixture, a column with a column head, a vapor transfer line, a condenser, a reflux tank, a reflux line, a distillate take off line, and a receiver vessel. Over a predominant amount of time during the (trans)esterification reaction at least a portion of the side product is continuously removed by distillate take off. The given pressure is continuously adjusted to maintain a range of the reaction temperature. The side product is removed in form of a mixture of the side product and the (meth )acry late starting material, and at least a portion of the converted (meth)acrylate starting material is compensated by adding a further amount of the (meth)acrylate starting material to the reaction mixture, preferably via a feed line to the reaction chamber or to the column. The (trans)esterification reaction is started at a pressure above 1.0 bar and the reaction process ends at a pressure of below 1.0 bar.
22), lithium hydroxide (LiOH), sodium methanolate (NaOMe), lithium methanolate (LiOMe), lithium fert-butoxide (LiOt-Bu), lithium /so-propoxide (LiOIPr), preferably wherein the strong basic catalyst comprises one or more compounds selected from the group consisting of lithium methanolate (LiOMe), and most preferably wherein the strong basic catalyst comprises or is lithium methanolate (LiOMe), wherein over a predominant amount of time during the (trans)esterification reaction at least a portion of the side product is continuously removed by distillate take off, and wherein over a predominant amount of time during the (trans)esterification reaction the given pressure is repeatedly adjusted in order to maintain a range of the reaction temperature, wherein the repeated adjustment of the given pressure is performed in pressure stages, preferably wherein the difference between two pressure stages is less than 500 mbar, and wherein the given pressure is repeatedly adjusted in a way to maintain the reaction temperature in the range of from 70°C to not more than 130°C.
The present invention relates to a computer-implemented method for monitoring pathogen load in livestock, using a risk matrix for evaluating the risk of a pathogen load in livestock to cause a disease, a computer program product comprising code portions adapted for performing the method according to the present invention, and a system for monitoring pathogen load in livestock.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
The present invention discloses process strategies and a method for the discontinuous (trans)esterification of (meth)acrylic esters. The method can prepare an alkyl (meth)acrylate product by a (trans)esterification reaction of a reaction mixture. The reaction mixture comprises a (meth)acrylate starting material and a first alcohol which are converted by the (trans)esterification reaction in the presence of a catalyst into the alkyl (meth)acrylate product and a side product. The (trans)esterification reaction is carried out in a reactor system. The reactor system comprises a heating and/or cooling system, a reaction chamber comprising the reaction mixture, a column with a column head, a vapor transfer line, a condenser, a reflux tank, a reflux line, a distillate transfer line, and a receiver vessel, over a predominant amount of time during the (trans)esterification reaction at least a portion of the side product is continuously removed by distillate take off. The pressure is constantly adjusted to keep the reaction temperature below a predetermined upper limit.
The present invention discloses a method for increasing a conversion rate of a (trans)esterification reaction for preparing a (meth)acrylate product.of a reaction mixture in a reactor system, the reactor system comprising a reboiler, a reaction chamber comprising the reaction mixture, a column with a column head, a vapor transfer line, a condenser, a reflux tank, a reflux line, a distillate take off line, and a receiver vessel, wherein the reaction mixture comprises at least one starting material which is converted by the reaction into at least one product, wherein the reaction mixture comprises (meth)acrylic acid as first starting material and a first alcohol as second starting material which are converted by the esterification reaction into a (meth)acrylate as a first product and water as a second product, or wherein in case of a transesterification reaction the reaction mixture comprises a (meth)acrylate as first starting material and a first alcohol as second starting material which are converted by the transesterification reaction into a second (meth)acrylate as a first product and a second alcohol as a second product, wherein while the reaction is running at least a portion of at least one of the products is removed by distillate take off, wherein the conversion rate of the reaction is increased by an intermediate increased or full removal of the at least one of the products present in the column, the column head and the condenser, and wherein - the intermediate increased or full removal of the at least one of the products present in the column, the column head, and the condenser while the reaction is running is performed by maximizing distillate take off and/or - during the intermediate increased or full removal of the at least one of the products present in the column, the column head and the condenser, the filling level for the reflux tank is minimized and the concentration of the removed products in the distillate is below a concentration of 50 wt%.
The invention relates to a composition for producing PU foam, preferably rigid PU foam, said composition comprising - at least one halogen-free polyester polyol and at least one halogenated polyol, - at least one physical blowing agent, - at least one flame retardant selected from (a) the group of phosphoric acid esters, preferably TCPP, TEP and/or TCEP, in particular TCPP and/or TEP, and/or (b) the group of phosphonates, preferably DMMP and/or DMPP, - red phosphorus, and at least one polyisocyanate component, the composition having an index of at least 200.
The invention relates to a process for producing polyether-siloxane block copolymers by hydrosilylation of alpha-omega-modified hydrogen siloxanes with alpha-omega-modified di-(meth)allyl polyethers in the presence of a hydrosilylation catalyst, wherein the reaction is carried out in a solvent mixture that comprises aromatic solvents and alkoxylated alcohol.
A blocked or reactive blocked polyurethane or polyurea oligomer composition, which comprises: a) a first blocked or reactive blocked polyurethane or polyurea oligomer, wherein the oligomer consists of a polyol moiety or polyamine moiety and multiple diisocyanate moieties, the number of the diisocyanate moieties is equal to the functionalities of the polyol or polyamine, wherein the amount of the oligomer is 10 wt. %-60 wt. %, based on the total weight of the oligomer composition; wherein the oligomer composition does not comprise any polyurethane or polyurea oligomer wherein both NCO-groups of the diisocyanate are reacted with both the polyol and a diol, or with both the polyamine and a diamine.
Process for producing a coated active anode material, wherein a mixed anode material and a pyrogenically produced, nanostructured and preferably surface modified of alumina, titania or a mixture thereof are subjected to dry mixing by means of a mixing unit having a specific electrical power of 0.05 – 1.5 kW per kg of the mixed anode material. The coated mixed anode material obtainable by this process. The anode for a lithium-ion battery and the lithium-ion battery comprising such coated active anode material.
Process for producing a coated mixed lithium transition metal oxide, wherein a mixed lithium transition metal oxide and a pyrogenically produced, nanostructured and, preferably, surface modified magnesium oxide are subjected to dry mixing by means of a mixing unit having a specific electrical power of 0.05 – 1.5 kW per kg of the mixed lithium transition metal oxide. The coated mixed lithium transition metal oxide obtainable by this process, the cathode for a lithium-ion battery, and the lithium-ion battery comprising the coated mixed lithium transition metal oxide mixed.
202100366 Foreign Filing 13 Summary5 The present invention concerns the recovery of methionylmethionine from aqueous alkali ions containing media by intermediate formation of Bis(methionyl)-diketopiperazine.
C07K 5/062 - Dipeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
C07C 319/20 - Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
C07C 321/14 - Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
C07D 241/08 - Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
44.
IMPROVED BIOTECHNOLOGICAL METHOD FOR PRODUCING GUANIDINO ACETIC ACID (GAA) BY USING NADH-DEPENDENT DEHYDROGENASES
The present invention relates to a microorganism transformed to be capable of producing guanidinoacetic acid (GAA) and comprising at least one gene coding for a protein having the function of a NADH-dependent dehydrogenase and to a method for the fermentative production of GAA using such microorganism. The present invention also relates to a method for the fermentative production of creatine.
The present invention relates to a microorganism transformed to be capable of producing guanidinoacetic acid (GAA) that has been improved by using a carbamate kinase (2.7.2.2) and L-arginine:glycine amidinotransferase (2.1.4.1) and to a method for the fermentative production of GAA using such microorganism which can be further improved by deleting the central repressor protein argR, expressing glyoxylate aminotransferase (2.6.1.-) or NADH-dependent amino acid dehydrogenase (1.4.1-). The present invention also relates to a method for the fermentative production of creatine by further expressing guanidinoacetate N-methyltransferase (2.1.1.2).
The present invention relates to a pyrogenically prepared surface modified magnesium oxide and a process for the preparation thereof as well as the use thereof.
Process for producing a coated active anode material, wherein a mixed anode material and a pyrogenically produced, nanostructured, and preferably surface modified magnesium oxide are subjected to dry mixing by means of a mixing unit having a specific electrical power of 0.05 – 1.5 kW per kg of the mixed anode material. The coated mixed anode material obtainable by this process. The anode for a lithium-ion battery and the lithium-ion battery comprising such coated active anode material.
B29C 51/26 - Component parts, details or accessories; Auxiliary operations
B29C 51/14 - Shaping by thermoforming, e.g. shaping sheets in matched moulds or by deep-drawing; Apparatus therefor using multilayered preforms or sheets
B29K 105/04 - Condition, form or state of moulded material cellular or porous
B29L 31/08 - Blades for rotors, stators, fans, turbines or the like, e.g. screw propellers
The invention relates to a continuous fiber-reinforced filament made of a thermoplastic material for use in additive manufacturing processes and to corresponding methods.
B29C 70/08 - Fibrous reinforcements only comprising combinations of different forms of fibrous reinforcements incorporated in matrix material, forming one or more layers, with or without non-reinforced layers
B32B 5/06 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by structural features of a layer comprising fibres or filaments characterised by a fibrous layer needled to another layer, e.g. of fibres, of paper
B32B 17/04 - Layered products essentially comprising sheet glass, or fibres of glass, slag or the like in the form of fibres or filaments bonded with or embedded in a plastic substance
B33Y 70/10 - Composites of different types of material, e.g. mixtures of ceramics and polymers or mixtures of metals and biomaterials
B29C 70/38 - Automated lay-up, e.g. using robots, laying filaments according to predetermined patterns
D01D 5/42 - Formation of filaments, threads, or the like by cutting films into narrow ribbons or filaments or by fibrillation of films
Spherical calcium silicate having (i) a d50 median particle size in a range from 1 to 35 µm, (ii) an oil absorption in a range from 40 to 130 mL/100g, (iii) a sphericity factor (S80) of greater than or equal to about 0.80, (iv) a BET surface area of between 10 – 125 m²/g, and (v) a %CaO from 0.5 – 20 wt-%. The spherical calcium silicate are produced by (a) continuously feeding a mineral acid and an alkali metal silicate into a loop reaction zone comprising a stream of liquid medium, wherein at least a portion of the mineral acid and the alkali metal silicate react to form a silica product in the liquid medium of the loop reaction zone; (b) continuously recirculating the liquid medium through the loop reaction zone; (c) continuously discharging from the loop reaction zone a portion of the liquid medium comprising the silica product; (d) filtrating and washing the liquid medium comprising the silica product; (e) combining the filtercake of step (d) with calcium hydroxide, (f) stirring the combined filter cake and calcium hydroxide of step (e) for 10min to 180 min (ageing step) and (g) drying the solution.. The spherical calcium silicate can be used in dentifrice compositions, food mixtures, personal care applications and liquid coatings.
111. The herbicidally active amount of L-glufosinate which is thus produced contacts the weed plant, thereby impairing its growth or leading to its dieback.
A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
The invention relates to (a) a composition suitable for producing polyurethane foam, comprising at least one polyisocyanate component, a polyol component, optionally a catalyst that catalyzes the forming of a urethane or isocyanurate bond, and optionally a blowing agent, the composition additionally comprising hydrocarbons KWS, Si-free surfactant and optionally polyalkyl siloxane, (b) to a method for producing polyurethane foam by using hydrocarbons KWS, Si-free surfactant and optionally polyalkyl siloxanes, (c) to the polyurethane foam thereby obtained, and (d) to the use thereof.
C08J 9/02 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by the reacting monomers or modifying agents during the preparation or modification of macromolecules
C08G 18/09 - Processes comprising oligomerisation of isocyanates or isothiocyanates involving reaction of a part of the isocyanate or isothiocyanate groups with each other in the reaction mixture
C08G 18/18 - Catalysts containing secondary or tertiary amines or salts thereof
13 2223 22444i4i) capable of converting N5-aminopentyl-N-(hydroxy)-succinamic acid to desferrioxamine B or H or at least one other linear desferrioxamine or bisucaberin according to Formula II.
The present invention relates to a recombinant microbial cell for producing at least one compound having structural Formula III from at least one simple carbon source: Formula (III) m = 1-3, wherein the simple carbon source is selected from the group consisting of glucose, sucrose, xylose, arabinose, mannose and glycerol; and wherein the cell comprises a further genetic modification to increase production of L-lysine in the cell from at least one of the simple carbon sources.
111. The herbicidally active amount of L-glufosinate which is thus produced contacts the weed plant, thereby impairing its growth or leading to its dieback.
The present invention relates to a recombinant microbial cell for producing N5-aminopentyl-N- (hydroxy)-succinamic acid of Formula I from at least one simple carbon source wherein the simple carbon source is selected from the group consisting of glucose, sucrose, xylose, arabinose, mannose, glycerol and combinations thereof and wherein the cell comprises a further genetic modification to increase production of L-lysine from at least one of the simple carbon sources.
The present invention relates to photostabilized compositions comprising a water-soluble tyrosine- containing compound with a molecular weight of below 1kDa and at least one photosensitive component and a method for stabilizing photosensitive components comprising the addition of a tyrosine-containing dipeptide.
202200074 Foreign Countries 11 ABSTRACT FOOD-CONTACT PLASTIC MATERIAL The present invention is related to afood-contact plastic material used in food packaging, the material comprising at least one up-conversion-based florescent marker, 5 wherein the food-contact plastic material is selected from the group consisting of High-Density Polyethylene (HDPE), Low-Density Polyethylene (LDPE), Linear Low Density Polyethylene (LLDPE), Polypropylene (PP), Polystyrene (PS), polyamide (PA), polyethylene-terephthalate (PET), Polyethylene terephthalate glycol (PETG) polymethylmethacrylate (PMMA), polycarbonate (PC), expanded polystyrene (EPS), expanded polypropylene (EPP), polyurethanes (PU), and 10 mixtures thereof; and wherein the fluorescent marker is an oxide or salt thereof of, at least one rare-earth metal.
B07C 5/00 - Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
B07C 5/34 - Sorting according to other particular properties
B29B 17/02 - Separating plastics from other materials
B32B 27/20 - Layered products essentially comprising synthetic resin characterised by the use of special additives using fillers, pigments, thixotroping agents
PTPRN2PTPRN2PTPRN2PTPRN2PTPRN2PTPRN2 in the test cell compared to the CpG site in the control is indicative of the test cell having OS caused by exposure of the cell to UV light and/or ageing.
C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
61.
DETECTING OXIDATIVE STRESS IN CELL(S) USING EPIGENETIC MEANS
The present invention is related to a method of identifying oxidative stress (OS) in a test cell, comprising (a) determining the methylation status of at least one CpG site in a DNA sample obtained from the test cell, (b) comparing the methylation status of the CpG site from (a) with that of a control without OS, wherein difference in the methylation status of the CpG site in the test cell compared to the CpG site in the control is indicative of the test cell having OS.
C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
Bacillus subtilisBacillus subtilis strain, and - at least one amino acid or peptide, wherein the amino acid is selected from glutamine, glutamic acid or salts thereof, and conjugated glutamine, and the peptide is an oligopeptide of 2-10 amino acid units in length, the amino acid units being natural amino acids, and at least one amino acid unit being a glutamine or glutamic acid unit.
A61K 8/99 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
A61K 8/64 - Proteins; Peptides; Derivatives or degradation products thereof
A61K 8/44 - Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts, esters or N-acylated derivatives thereof
A23K 10/12 - Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
A23K 10/30 - Animal feeding-stuffs from material of fungal origin, e.g. mushrooms
A23K 20/147 - Polymeric derivatives, e.g. peptides or proteins
The invention refers to a dosage form comprising a core comprising at least one biologically active ingredient a specific intermediate coating layer inter alia comprising at least one alkaline agent and at least one release acceleration agent selected from from iron oxide, aluminium oxide, titanium dioxide, dimethyl sulfoxide, zinc oxide, sucrose, maltose, lactose, dextrates, glucose, fructose, dyes, or any mixture thereof and an enteric coating layer and a method for obtaining the dosage form. Furthermore, the invention refers to the use of the dosage form according to the present invention for providing at least 80% drug release at pH value 5 within 60 min or at least 80% drug release at pH value 3 within 60 min.
Disclosed herein is a method of producing a polyurethane foam block (137') using a foam production machine (100) configured for producing polyurethane foam as a slabstock (137) using a continuous slabstock process defined by at least one process parameter, such as a raw material output factor or a conveyor speed. The foam production machine includes a mixing head (102) configured to mix precursor reagents for forming a reactive mixture (136), and a conveyor (106) configured to receive the reactive mixture. The method comprises: mixing (800) the precursor reagents in the mixing head to provide the reactive mixture; dispensing (802) the reactive mixture to initiate foaming of the reactive mixture; receiving (804) the reactive mixture by the conveyor; cutting (806) the polyurethane foam block from an end portion of the slabstock to produce a cut surface (724); acquiring (808) a digital image (742) of the cut surface using an imaging system (706); inputting (810) the digital image into a pattern recognition module (762), the pattern recognition module being configured to recognize at least one pattern being indicative of at least one macroscopic polyurethane foam defect, and being configured to output an identification (766) of a presence of the at least one macroscopic polyurethane foam defect in response to recognizing the respective pattern in the digital image; and inputting (812) the identification of the presence of the at least one macroscopic polyurethane foam defect into a control module (764), the control module being configured to process the inputted identification in order to output a control signal for changing the least one process parameter of the continuous slabstock process.
A method for setting machine parameters of a foam production machine is provided. The foam production machine includes an intermediate conveyance unit configured to receive a reactive mixture, a plurality of fall plates having vertically adjustable ends and configured to receive the reactive mixture from the intermediate conveyance unit, and a conveyor configured to receive the reactive mixture from the fall plates. The method includes executing software by a computer system, where executing the software includes importing characteristics of the foam production machine and a rise profile for the reactive mixture, and iteratively determining process and machine parameters, including reactive mixture flow rate, conveyor speed, a dimension of the intermediate conveyance unit, and vertical positions for the ends of each fall plate resulting in a predefined predicted profile of the reactive mixture on the plurality of fall plates.
B29C 44/28 - Expanding the moulding material on continuous moving surfaces
B29C 44/48 - Feeding the material to be shaped into an open space or onto moving surfaces, i.e. to make articles of indefinite length by gravity, e.g. casting onto, or between, moving surfaces
B29C 44/46 - Feeding the material to be shaped into an open space or onto moving surfaces, i.e. to make articles of indefinite length
68.
IMPROVED METHOD FOR DEPOLYMERISING POLYETHYLENE TEREPHTHALATE
The invention relates to a method for depolymerising polyethylene terephthalate ("PET"), in which PET is reacted with electrolytically prepared alkali metal glycolate, in particular sodium or potassium glycolate, to form a mixture M1 comprising bis(2-hydroxyethyl) terephthalate ("BHET"). The method according to the invention is characterised in that BHET accounts for a particularly high proportion of the breakdown products in the mixture M1. As a result, the method according to the invention provides a high yield of BHET, which can be used directly for renewed PET production. The present invention also relates to a method for recycling PET, in which the BHET obtained in the method for depolymerising PET is polymerised again to PET, optionally after further purification from M1.
C08J 11/22 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds
C08J 11/24 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds containing hydroxyl groups
C08L 67/00 - Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
C08L 67/02 - Polyesters derived from dicarboxylic acids and dihydroxy compounds
The present invention relates to a method for the depolymerization of polyethylene terephthalate (PET), in which method PET is reacted with sodium glycolate or potassium glycolate which has been obtained via reactive distillation, to form a mixture M1 comprising bis(2-hydroxyethyl) terephthalate (BHET). The method according to the invention is characterized in that BHET forms a particularly high proportion of the cleavage products in the mixture M1. As a result, the method according to the invention provides a high yield of BHET, which can be used directly to produce PET again. The present invention therefore also relates to a method for recycling PET, in which method the BHET that is obtained in the method for the depolymerization of PET and, if necessary, has been further purified from M1, is repolymerized to form PET.
B01J 23/16 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
C08J 11/18 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material
C08J 11/22 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds
C07C 31/30 - Alkali-metal or alkaline-earth-metal alcoholates
B01J 23/16 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
C08J 11/16 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with inorganic material
C08J 11/18 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material
C08J 11/22 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds
C08J 11/24 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic oxygen-containing compounds containing hydroxyl groups
C07C 31/30 - Alkali-metal or alkaline-earth-metal alcoholates
71.
OPTICAL DETERMINATION OF A CONTROL SIGNAL FOR SLABSTOCK POLYURETHANE FOAM PRODUCTION
Disclosed herein is a method of producing a polyurethane foam block (137) using a foam production machine (100) configured for producing polyurethane foam as a slabstock (137) using a continuous slabstock process defined by at least one process parameter, such as a raw material output factor or a conveyor speed, the foam production machine including a mixing head (102) configured to mix precursor reagents for forming a reactive mixture, and a conveyor (106) configured to receive the reactive mixture. The method comprises: mixing (800) the precursor reagents in the mixing head to provide the reactive mixture; dispensing (802) the reactive mixture to initiate foaming of the reactive mixture; receiving (804) the reactive mixture by the conveyor; cutting (806) the polyurethane foam block from an end portion (720) of the slabstock to produce a cut surface (724), wherein the polyurethane foam comprises foam cells, wherein the intersection of the cut surface with the foam cells forms a foam cell structure (906); acquiring (808) a digital image (742) of at least a portion of the cut surface using an imaging system (706), wherein the digital image depicts the foam cell structure; inputting (810) the digital image into a trained machine learning module (762, 1000, 1200), the trained machine learning module being trained to produce a two-dimensional segmentation (1012) of the foam cell structure at the cut surface; and receiving (812) a control signal (744) for changing the least one process parameter of the continuous slabstock process in response to inputting the digital image into the trained machine learning module.
Disclosed herein is a method of producing a polyurethane foam block (137') using a foam production machine (100) for producing polyurethane foam as a slabstock (137) The method comprises: mixing (800) the precursor reagents in a mixing head (102) to provide a reactive mixture; dispensing (802) the reactive mixture; receiving (804) the reactive mixture by a conveyor (106); cutting (806) the polyurethane foam block from the slabstock to produce a cut surface (724) with a foam cell structure (906); acquiring (808) a digital image (742) of the cut surface; inputting (810) the digital image into a trained machine learning module (762, 1000, 1200), the trained machine learning module being trained to produce a two-dimensional segmentation (1012) of the foam cell structure for the prediction of a foam parameter (744); and signaling (812) the foam parameter in response to inputting the digital image into the trained machine learning module.
A method for determining machine parameters of a foam production machine is provided. The foam production machine includes a mixing head configured to mix precursor reagents for forming a reactive mixture, a plurality of inclined fall plates, where a first inclined fall plate is configured to receive the reactive mixture, and where each inclined fall plate has vertically adjustable ends, and a conveyor configured to receive the reactive mixture from a last inclined fall plate, the conveyor having an adjustable conveyor speed. The method includes executing software by a computer system, including accessing a database for reading a rise profile for the reactive mixture of the precursor reagents and computing, based on the rise profile, vertical positions for the ends of each inclined fall plate and the conveyor speed resulting in a predefined predicted profile of the reactive mixture on the plurality of inclined fall plates.
The present disclosure provides latent amine compositions which are used as a curing agent for flame resistant epoxy systems, the amine-epoxy resin compositions, and the cured products from amine-epoxy composition.
C08G 59/40 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups characterised by the curing agents used
C08G 59/68 - Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups characterised by the catalysts used
C08L 63/00 - Compositions of epoxy resins; Compositions of derivatives of epoxy resins
75.
ELECTROCHEMICAL OXIDATION OF CYCLOALKANES TO FORM CYCLOALKANONE COMPOUNDS
The invention relates to a process for preparing unsubstituted or at least monosubstituted cycloalkanones by electrochemical oxidation of unsubstituted or at least monosubstituted, saturated cycloaliphatic hydrocarbons by electrochemical oxidation in the presence of an organic nitrate salt in an electrolytic cell in a reaction medium in the presence of oxygen.
The invention relates to a method for producing unsubstituted or at least monosubstituted α,ω-dicarboxylic acids or ketocarboxylic acids and unsubstituted or at least monosubstituted cycloalkanones by electrochemically oxidizing unsubstituted or at least monosubstituted monounsaturated or polyunsaturated cycloalkenes and unsubstituted or at least monosubstituted saturated cycloaliphatic hydrocarbons in the presence of an inorganic or organic nitrate salt in an electrolysis cell in a reaction medium in the presence of oxygen.
The invention relates to a process for preparing unsubstituted or at least monosubstituted α,ω-dicarboxylic acids and ketocarboxylic acids by electrochemical oxidation of unsubstituted or at least monosubstituted, monosaturated or polysaturated cycloalkenes by electrochemical oxidation in the presence of an organic nitrate salt in an electrolytic cell in a reaction medium in the presence of oxygen.
The invention relates to a process for preparing aliphatic monocarboxylic acids and α,ω-dicarboxylic acids or α,ω-dicarboxylic acid monoesters by electrochemical oxidation of unsubstituted or at least monosubstituted, monosaturated or polysaturated fatty acids or fatty acid esters in the presence of an inorganic or organic nitrate salt in an electrolytic cell in a reaction medium in the presence of oxygen.
The present invention refers to a polynucleotide delivery particle, comprising a) at least one poly(lactic-co-glycolide); b) at least one cationic surfactant; c) at least one polynucleotide; and d) optionally at least one additive; wherein the poly(lactic-co-glycolide) has a weight average molecular weight Mw of 1000 to 9500 g/mol measured via gel permeation chromatography using polystyrene standards and chloroform. Furthermore, the present invention pertains to a method of forming the polynucleotide delivery particle according to the present invention, wherein the particle is formed by a nanoprecipitation or nanoemulsion method. Moreover, the present invention refers to an oral drug delivery composition or a parenteral drug delivery composition comprising at least one polynucleotide delivery particle according to the present invention as well as their use as a medicament.
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
A61K 47/62 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
80.
CO-PRECIPITATES OF METHIONYLMETHIONINE WITH ORGANIC COMPOUNDS
The present invention concerns a co-precipitate of methionylmethonine with at least one further organic compound, preferably with aminolevulinic acid, PQQ or thiamine, methods for preparing such co-precipitates and the use of such co-precipitates, in particular as feed and food additives and as pharmaceutical.
A23K 20/147 - Polymeric derivatives, e.g. peptides or proteins
A23K 50/80 - Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
C07C 229/22 - Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
C07K 5/062 - Dipeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
81.
POWDER FOR USE IN A LAYERWISE PROCESS WITH LASERS IN THE VISIBLE AND NEAR-INFRARED RANGE
The present invention relates to powders for additive manufacturing processes, wherein the powder contains composite particles containing an NIR-absorbing component as core particles. This allows uniform melting of the powder.
B29C 64/153 - Processes of additive manufacturing using only solid materials using layers of powder being selectively joined, e.g. by selective laser sintering or melting
PP P- PPPPIIIA PIIIA PIIIA IIIBIIIB, which is then employed in steps (ii) and (iii). The L-glufosinate P-ester obtained in the methods according to the first or second aspect of the invention may be saponified to give L-glufosinate.
The invention refers to a process for preparing a polymer-coated hard shell capsule comprising at least an intermediate coating layer and an enteric coating layer and optionally a top coating layer, suitable as container for pharmaceutical or nutraceutical biologically active ingredients, wherein the hard shell capsule comprises a body and a cap, wherein in the closed state the cap overlaps the body either in a pre-locked state or in a final-locked state, wherein the hard shell capsule is provided in the pre-locked state and is coated with a first coating solution, suspension or dispersion comprising or consisting of a1) at least one polymer; b1) at least one alkaline agent; c1) optionally at least one glidant; and d1) optionally at least one additive, different from a1) to c1); to obtain the intermediate coating layer of the hard shell capsule in the pre-locked state; and thereafter is coated with a second coating solution, suspension or dispersion, which is different from the first coating solution, suspension or dispersion, comprising or consisting of a2) at least two polymers; b2) optionally at least one glidant; c2) optionally at least one emulsifier; d2) optionally at least one plasticizer; e2) optionally at least one biologically active ingredient; and f2) optionally at least one additive, different from a2) to e2); wherein the first polymer is an anionic polymer having a Tgm ≥ 35°C; wherein the second polymer is a polymer having a Tgm of ≤ 30 °C; to obtain the enteric coating layer of the hard shell capsule in the pre-locked state, wherein the total coating amount of the coating layers is 2.0 to 10 mg/cm2. Furthermore, the invention refers to a polymer-coated hard shell capsule obtained from the process according to the invention and the use of the polymer-coated hard shell capsule providing less than 10% drug release at 0.1N HCl for 120 minutes followed by at least 80% drug release at pH value 5 within additional 150 min.
The present invention relates to a method for producing pressed products made of a crosslinkable material based on an elastomer-containing powder or granulate, in particular a recycled material such as scrap tyres. The method also relates to the pressed products obtained therefrom and to the further processing thereof. The pressed products are very well suited for further processing to form crosslinked elastomer compounds and moulded bodies formed therefrom, and for the substitution of raw rubber or compositions containing raw rubber.
The present invention relates to polynucleotides encoding an amino acid sequence encoding a collagen protein or a bacterial collagen-like protein, comprising an N-terminal signal sequence as well as a fermentative process for secreting bacterial collagen-like proteins in a host.
The invention relates to a method of manufacturing an RNA- or DNA-containing virus particle in cell culture, a supplement for a culture medium and a culture medium for use in the production of RNA or DNA-containing virus particles, comprising one or more dipeptides or derivatives thereof, wherein one dipeptide is glycyl-glutamine (Gly-GIn).
The present invention relates to a method of preparing a sponge based on collagen-like proteins comprising the steps: i) providing an aqueous solution, preferably having a pH value of 6 to 8, comprising at least one collagen-like protein and optionally at least one additive; ii) cross-linking the at least one collagen-like protein with at least one cross-linker via incubation to obtain a hydrogel; iii) optionally washing the hydrogel with a buffer; iv) performing a lyophilization step to obtain the sponge; v) optionally adding at least one additive; and vi) optionally sterilizing, preferably via plasma, gamma or UV treatment, the obtained sponge. Furthermore, the present invention pertains to a sponge obtained by the method according to the present invention and use of the sponge for wound sealing, haemostasis, wound plugging, healing promotion, bone regeneration, cartilage repair, cell cultures, production of vegetarian or vegan meat, the absorption of biological fluids, like blood or wound exudate.
The present invention refers to a precoated hard-shell capsule with at least one coating layer, suitable as container with an improved protective effect against atmospheric oxygen for pharmaceutical or nutraceutical biologically active ingredients and to a method for preparing a pharmaceutical delivering system comprising a hard-shell capsule and a fill, the fill comprising a pharmaceutically or nutraceutically active ingredient.
The invention relates to a liposomal composition comprising biosurfactants and the use of the liposomal composition for encapsulation of at least one cosmetic, pharmaceutical and/or nutraceutical active ingredient.
The present invention relates to an improved process for depolymerization of polyurethanes under mild conditions and low salt concentration in the reaction mixture, wherein polyether polyols and polyamines can be recovered in high yields.
C08J 11/14 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with steam or water
C07C 209/62 - Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
C07C 211/49 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton
C08G 18/00 - Polymeric products of isocyanates or isothiocyanates
C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
The invention relates to a composition, the main surfactant content of which is mainly bio based. The invention also relates to the use of the composition for cleaning, especially of cleaning of textiles or fabrics, preferably for cleaning of fatty stains.
C11D 10/04 - Compositions of detergents, not provided for by any single one of main groups based on mixtures of surface-active non-soap compounds and soap
The present invention relates to an improved process for depolymerization of polyurethanes under mild conditions and low salt concentration in the reaction mixture, wherein polyether polyols and polyamines can be recovered in high yields.
C08J 11/14 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with steam or water
C07C 209/62 - Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
C07C 211/49 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring having at least two amino groups bound to the carbon skeleton
C08G 18/00 - Polymeric products of isocyanates or isothiocyanates
C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
Process for producing PU foams, preferably flexible PU foams by reacting at least one polyol component, comprising recycled polyol, with at least one isocyanate component in the presence of one or more catalysts that catalyze the isocyanate-polyol and/or isocyanate-water reactions and/or isocyanate trimerization, characterized in that the recycled polyol was obtained by hydrolysis of a polyurethane, comprising contacting said polyurethane with water in the presence of an organic amine base.
C08J 11/28 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with organic material by treatment with organic compounds containing nitrogen, sulfur or phosphorus
C08J 9/12 - Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
C08J 11/14 - Recovery or working-up of waste materials of polymers by chemically breaking down the molecular chains of polymers or breaking of crosslinks, e.g. devulcanisation by treatment with steam or water
The subject of the present invention are microorganisms with reduced competence and compositions containing such microorganisms, in particular feed, food and pharmaceutical compositions.
The present invention relates to Bacillus strains with improved outgrowth and/or germination characteristics and their use in feed, food and pharmaceutical compositions.
The invention relates to a spiral-wound module (0) comprising a permeate tube (1), a spiral-wound coil (6), two ATDs (2f, 2r) and an outer tube (3) which extends coaxially with respect to the permeate tube (1), encloses the spiral-wound coil (6) and is joined to both ATDs (2f, 2r). It addresses the problem of specifying a spiral-wound module (0) which can be used at high operating temperatures, preferably above 150°C, and has a simple, robust and inexpensive design. This problem is solved in that the ATDs (2f, 2r) are fitted onto the permeate tube (1) and each lie against the respective end face of the spiral-wound coil (6), at least one of the two ATDs (2r) has a sleeve-like extension which is enclosed at its circumference by the outer tube (3) in such a way that a force-fit and/or form-fit connection (8) between the outer tube (3) and the ATD (2r) is realised via the extension (7) of the latter.
The present invention relates to a process for preparing an 1,2-alkanediol from the corresponding alkene and hydrogen peroxide which does not require isolation and purification of the intermediate alkene oxide.
C07C 29/10 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
C07D 301/12 - Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with hydrogen peroxide or inorganic peroxides or peracids
98.
HIERARCHICALLY STRUCTURED SI/C AGGLOMERATES MADE BY SPRAY DRYING
The present invention relates to a method for making a micrometer-sized agglomerate powder for use as active anode material, a spray dried micrometer-sized agglomerate powder comprising nanometer-sized silicon-containing particles and a polymeric binder, a coating composition comprising the micrometer-sized agglomerate powder, a method for making an anode or an energy storage device comprising the step of applying the coating composition onto an anode substrate, and an anode or energy storage device comprising the micrometer-sized agglomerate powder.
GalliformesGalliformes family; and wherein at least three LMRs are amplified in step (b) and with a proviso that the CpG sites associated with single nucleotide polymorphisms are not considered.
C12Q 1/6881 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
The present invention relates to an aquaculture feed composition comprising an optimum concentration of at least three fatty acids selected from LOA, LNA, ARA, EPA and DHA to improve stress resistance. The invention further concerns a method of producing an aquaculture meat product, by feeding farmed fish an aquaculture feed composition, said method comprising the step of formulating aquaculture feed composition comprising an optimum concentration of at least three fatty acids selected from LOA, LNA, ARA, EPA and DHA to improve stress resistance of the farmed fish. The optimum concentration of said at least three fatty acids is adapted to the breed of the fish, and the different stages of growth of the fish as determined by its weight.