Abstract

2n-1(n-1)yn(1+x)n(3+2x)+1y(n-1)y(n-1) (I), where A' is an organic ammonium compound, preferably selected from benzylammonium, phenylethylammonium, n-propylammonium, phenylammonium, histammonium, cyclopentylammonium, cyclohexylammonium, cyclohexylmethylammonium, 4-ammonium butyric acid, 5-ammonium valeric acid, or isobutylammonium, FA is formamidinium, MA is methylammonium, n is between 3 and 9, x is between 0.1 and 0.25, and y is between 0.2 and 0.6.

IPC Classes  ?

• H01L 51/46 - Selection of materials

Abstract

The present invention relates to a piezoelectric, epitaxially grown pseudosubstrate comprising a silicon wafer (100) having two parallel faces, and a thin layer of α-quartz (100) grown epitaxially on one of the faces of said wafer, said thin α-quartz layer (100) exhibiting a uniform crystallization with a mosaicity around the peak (100) of the quartz of between 6° and 1° and a thickness of between 100 nm and 1 μm. The present invention also relates to a process for fabricating such a pseudosubstrate, and to the use thereof for producing piezoelectric membranes.

IPC Classes  ?

• C30B 7/10 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions by application of pressure, e.g. hydrothermal processes
• C30B 29/16 - Oxides
• C30B 29/60 - Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape characterised by shape
• C30B 7/02 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions by evaporation of the solvent
• C30B 29/18 - Quartz
• C30B 33/02 - Heat treatment
• C30B 5/00 - Single-crystal growth from gels
• C30B 29/20 - Aluminium oxides

Abstract

The invention relates to a method for obtaining a nanostructured layer of titanium nitride by deposition by cathode sputtering of a substrate at ambient temperature, characterised in that it comprises: - a first step of reactive cathode sputtering at ambient temperature in a vacuum chamber comprising a reactive gas, an inert gas, the substrate with a diameter of 100 mm or more, and a target cathode, under specific conditions; - a second step of wet etching of the monolayer of titanium nitride deposited during the first step, the wet etching comprising the application of a solution, in order to obtain a thin monolayer of titanium nitride, TiN, having controlled black coloration, the reactive cathode sputtering being carried out during the first step using a discharge provided by a direct current generator, the reactive gas being composed of nitrogen, with a predetermined flow rate of inert gas and of reactive gas entering the chamber, a predetermined ratio of inert gas and of reactive gas, a predetermined pressure in the chamber and a predetermined power of the direct current generator. Varying these parameters or not adhering to the ratio no longer provides the nanostructuring obtained in step 2.

IPC Classes  ?

• C23C 14/00 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
• C23C 14/06 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
• C23C 14/54 - Controlling or regulating the coating process
• C23C 14/58 - After-treatment
• C23C 28/04 - Coating for obtaining at least two superposed coatings either by methods not provided for in a single one of main groups , or by combinations of methods provided for in subclasses and only coatings of inorganic non-metallic material

Abstract

The present invention relates to an aqueous composition intended to be applied to a substrate in order to form thereon a protective barrier coating against external attacks. It comprises, as a mixture: A. 84 to 99 parts by weight of an aqueous solution of at least one alkali metal silicate (A1) and/or of a solution prepared by dissolving amorphous silica in an aqueous solution of at least one alkali metal hydroxide (A2); B. 0 to 11 parts by weight of at least one alkali metal hydroxide; and C. 1 to 5 parts by weight of at least one from the polydimethylsiloxanes of formula: [Chem. 3] in which n is a number from 90 to 410, silicone oils and fluorosilanes, per 100 parts by weight of (A)+(B)+(C), the Si/M molar ratio of the composition being between 0.5 and 2.5, where, in this ratio, Si is the silicon of the silicate(s) of the solution (A1) and/or (A2) and M represents the alkali metal(s) of the silicate(s) of (A1) and/or (A2) and of the alkali metal hydroxide of (B).

IPC Classes  ?

• C09D 1/02 - Coating compositions, e.g. paints, varnishes or lacquers, based on inorganic substances alkali metal silicates
• C09D 5/00 - Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
• C09D 7/61 - Additives non-macromolecular inorganic
• C09D 7/65 - Additives macromolecular
• C08K 3/22 - Oxides; Hydroxides of metals

Abstract

The invention relates to a compound having one of the following ionic chemical structures (I), "R" represents an "alkyl" or "O-alkyl" group optionally comprising one or more unsaturations, as a linear or branched chain, of 1 to 30 carbon atoms, optionally substituted; R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R12 represent, independently of one another, an atom or a group of atoms; "(Het)aryl" independently represents an aryl or heteroaryl group; and "A" represents an anion.

IPC Classes  ?

• C07D 413/10 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
• G01T 1/202 - Measuring radiation intensity with scintillation detectors the detector being a crystal

Abstract

The present invention concerns novel Gram-negative bacteria efflux pump inhibitors. It further relates to the use of Gram-negative bacteria efflux pump inhibitors to prevent and/or treat antibiotic resistance by potentiating the activity of antibiotics. Infections by multidrug resistant (MDR) Gram-negative bacteria are a major threat to global healthcare. The inventors have discovered a novel class of Resistance Nodulation cell Division-efflux pump inhibitors. The inventors tested the effects of these inhibitors on growth inhibition of different bacteria as well as their impact on the boosting of antibiotic activity in different bacteria. Particularly, the inventors tested the effects of these inhibitors on E. coli, A. baumannii, K. pneumoniae and P. aeruginosa.

IPC Classes  ?

• C07D 213/74 - Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
• C07D 215/38 - Nitrogen atoms
• C07D 217/22 - Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
• C07D 241/44 - Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
• C07D 295/073 - Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
• C07D 471/08 - Bridged systems
• C07D 487/04 - Ortho-condensed systems
• C07D 487/08 - Bridged systems
• C07D 498/04 - Ortho-condensed systems
• A61P 31/04 - Antibacterial agents
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene

Abstract

The positioning system (9) comprises a device (10) and a plurality of fixed bases (12), which comprise a counter cyclically scanning n positions of the pointer. The device comprises a transmitter configured to transmit a request comprising at least one pattern of points, the values read with the pointer of which modulate a carrier. Each receiving base transmits a response: a) repeating the pattern received by the base from the device, and/or b) representative of a first pattern time offset, measured by the base, between the received pattern and an identical pattern stored in the memory of the base. The device comprises: - a means for measuring a second pattern time offset between the point values of the pattern received in each response and the values stored in the memory of the device, - a means for determining the distance between the device and each base according to: a) the total pattern offset between the pattern transmitted by the device and the repeated pattern received by the device from the base, and/or b) the second pattern offset and the first pattern offset measured by the base.

IPC Classes  ?

• G01S 5/14 - Determining absolute distances from a plurality of spaced points of known location
• G01S 13/82 - Systems using reradiation of radio waves, e.g. secondary radar systems; Analogous systems wherein continuous-type signals are transmitted
• G01S 13/84 - Systems using reradiation of radio waves, e.g. secondary radar systems; Analogous systems wherein continuous-type signals are transmitted for distance determination by phase measurement
• G01S 13/87 - Combinations of radar systems, e.g. primary radar and secondary radar
• G01S 5/00 - Position-fixing by co-ordinating two or more direction or position-line determinations; Position-fixing by co-ordinating two or more distance determinations
• G01S 11/02 - Systems for determining distance or velocity not using reflection or reradiation using radio waves

Abstract

The present invention relates to a multilayer material, comprising a solid substrate coated at least partially with a textured α-quartz buffer layer (100), the crystallographic direction [100] of the α-quartz being parallel to the crystallographic direction [100] of the silicon (100); and on said α-quartz buffer layer (100), a layer of one-dimensional epitaxial ZnO microcrystals (110) (or epitaxial ZnO microwires), said microcrystals being self-assembled. The present invention also relates to a method for producing such a multilayer material, as well as to the industrial use thereof in various technical fields.

IPC Classes  ?

• C30B 7/10 - Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions by application of pressure, e.g. hydrothermal processes
• C30B 29/16 - Oxides
• C30B 29/60 - Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape characterised by shape

Abstract

4810822n48108222O} (x≥0), in the separation/capture of molecules having a size of less than 5 A, notably in the separation of molecules governed (i) by specific interactions with the groups -OH, -CO2H and/or -CO2- present on the surface of the pores of said MOF and/or (ii) by size exclusion by favoring the selective adsorption of molecules having sizes smaller than those of the pores of said MOF.

IPC Classes  ?

• C07C 51/41 - Preparation of salts of carboxylic acids by conversion of the acids or their salts into salts with the same carboxylic acid part
• B01D 15/00 - Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
• B01J 20/22 - Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
• B01J 31/16 - Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
• C07F 5/06 - Aluminium compounds

Abstract

The present invention relates to the preparation of a microstructured scaffold corresponding to a biocompatible membrane-type support material for cell culture. The present invention also relates to a composition comprising said microstructured scaffold, and cells, in particular photoreceptors. The present invention applies in particular to the preparation of an implantable graft for the treatment of diseases of the retinal pigment epithelium and of the neural retina.

IPC Classes  ?

• C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means

Abstract

pre-scan)presumptiveprobeproberobe) is illuminated.

IPC Classes  ?

• G02B 21/00 - Microscopes

Abstract

EEEsss) is illuminated.

IPC Classes  ?

• G02B 21/00 - Microscopes

Abstract

12MIRMIR122.

IPC Classes  ?

• G02F 1/35 - Non-linear optics
• G02F 1/39 - Non-linear optics for parametric generation or amplification of light, infrared, or ultraviolet waves

Abstract

161616166)alkoxy, said process comprising a step of intramolecular cyclisation, a step of bromination, a step of aromatization and a step of oxidation.

IPC Classes  ?

• C07C 39/38 - Halogenated derivatives with at least one hydroxy group on a condensed ring system containing two rings
• C07C 45/51 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
• C07C 51/235 - Preparation of carboxylic acids or their salts, halides, or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups of —CHO groups or primary alcohol groups
• C07C 51/373 - Preparation of carboxylic acids or their salts, halides, or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in doubly bound form
• C07C 51/377 - Preparation of carboxylic acids or their salts, halides, or anhydrides by reactions not involving formation of carboxyl groups by hydrogenolysis of functional groups
• C07C 57/58 - Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
• C07C 59/88 - Unsaturated compounds containing keto groups containing halogen
• C07C 59/90 - Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
• C07C 45/54 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
• C07C 37/07 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by conversion of non-aromatic six-membered rings or of such rings formed in situ into aromatic six-membered rings, e.g. by dehydrogenation with simultaneous reduction of C=O group in that ring
• C07C 39/14 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings with at least one hydroxy group on a condensed ring system containing two rings
• C07C 43/295 - Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing hydroxy or O-metal groups
• C07C 45/63 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of C=O groups by substitution of halogen atoms by other halogen atoms
• C07C 46/06 - Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
• C07C 47/24 - Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
• C07C 49/697 - Unsaturated compounds containing a keto group being part of a ring containing halogen containing six-membered aromatic rings
• C07C 50/24 - Quinones containing halogen
• C07C 59/64 - Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
• C07C 59/84 - Unsaturated compounds containing keto groups containing six-membered aromatic rings
• C07C 49/753 - Unsaturated compounds containing a keto group being part of a ring containing ether groups, groups, groups, or groups
• C07C 45/45 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation

Abstract

The present invention relates to a crosslinkable two-component composition comprising: - a component A comprising: - an iodonium salt having one of the formulae (I-A), (I-B) or (I-C); - at least one (meth)acrylate monomer M1 having one of the formulae (II), (III) or (IV), - an organic or mineral acid having a pKa or pka1 ranging from 0.3 to 5 measured in water at 25°C; - a copper salt or a copper complex; - a component B containing at least one dihydropyridine compound having one of the formulae (VI) to (X), wherein said composition does not contain peroxide.

IPC Classes  ?

• C08F 4/40 - Redox systems
• C09J 4/00 - Adhesives based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond

Abstract

The present invention relates to a crosslinkable two-component composition comprising: - a component A comprising: - an iodonium salt having one of the formulae (I-A), (I-B) or (I-C); - at least one (meth)acrylate monomer M1, - an organic or mineral acid having a pKa or pka1 ranging from 0.3 to 5 measured in water at 25°C; - at least one photoinitiator P1; - a component B containing at least one dihydropyridine compound having one of the formulae (III) to (VI), wherein said composition does not contain peroxide.

IPC Classes  ?

• C08F 4/48 - Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths, or actinides selected from alkali metals selected from lithium, rubidium, caesium, or francium
• C08F 4/50 - Metals; Metal hydrides; Metallo-organic compounds; Use thereof as catalyst precursors selected from light metals, zinc, cadmium, mercury, copper, silver, gold, boron, gallium, indium, thallium, rare earths, or actinides selected from alkaline earth metals, zinc, cadmium, mercury, copper, or silver
• C09J 4/00 - Adhesives based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond

Abstract

The present invention relates to a method for the discriminant monitoring of a composite multi-material assembly (1) comprising at least one internal layer (10) made of a first, electrically conductive composite material and a second layer (11) made of a second, electrically insulating composite material, the second layer (11) covering the first internal layer (10). According to the invention, the method comprises the following steps: - preparing the composite multi-material assembly (1) by exposing a portion (101) of the internal layer (10), which constitutes a first electrode; - applying a second electrode (103) to the surface of the second layer (11), one of these electrodes (103) being earthed; - performing discriminant monitoring wherein a current is generated between the first electrode (101) and the second electrode (103) by applying a threshold voltage Us predetermined by calibration to characterise a lack of structural defects, the appearance of a breakdown at a voltage lower than said threshold voltage Us being indicative of the presence of at least one structural defect in the composite assembly (1).

IPC Classes  ?

• G01L 5/00 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes
• G01N 27/72 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables

Abstract

The invention relates to an YjgCD-type protein complex, wherein said complex has an enzymatic activity of formate dehydrogenase and/or of carbon dioxide reductase and the complex is oxygen resistant. The complex comprises at least a YjgC-type protein and YjgD-type protein, said YjgC-type protein comprising an amino acid sequence as set forth in SEQ ID NO: 1 or any homologous sequence derived from said sequence SEQ ID NO: 1 and the YjgD-type protein comprising an amino acid sequence as set forth in SEQ ID NO: 3 or any homologous sequence derived from said sequence SEQ ID NO:3.

IPC Classes  ?

• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase

Abstract

030NN) to each one of said conducting rails; wherein: the pitch P of said conducting rails is smaller than an optical wavelength λ; and the height H of said conducting rails is at least equal to λ/Δn, An being the birefringence of the liquid crystal at said optical wavelength.

IPC Classes  ?

• G02F 1/29 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the position or the direction of light beams, i.e. deflection
• G02F 1/13 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulating; Non-linear optics for the control of the intensity, phase, polarisation or colour based on liquid crystals, e.g. single liquid crystal display cells

Abstract

This computer-implemented method for delivering audio-visual media on-demand allows one or more digital video files to be sequenced and the sequences generated by the sequencing to be indexed, by dividing virtually the one or more digital video files into digital virtual sequences, each bounded virtually by two sequence time markers. The method is intended to produce and select automatically virtual sequences of each digital video file, the file fragments corresponding to the virtual sequences then being able to be extracted from the digital video files in question to be viewed or recorded in a new digital video file.

IPC Classes  ?

• H04N 21/432 - Content retrieval operation from a local storage medium, e.g. hard-disk
• H04N 21/472 - End-user interface for requesting content, additional data or services; End-user interface for interacting with content, e.g. for content reservation or setting reminders, for requesting event notification or for manipulating displayed content
• G06F 16/73 - Querying
• H04N 21/84 - Generation or processing of descriptive data, e.g. content descriptors

Abstract

2-2γ2γ52-2γ2γ27233, the molar content of alumina being between 5 and 15% of the total composition of the environmental barrier.

IPC Classes  ?

• C04B 41/87 - Ceramics
• C04B 41/89 - Coating or impregnating for obtaining at least two superposed coatings having different compositions

Abstract

The invention relates to a haptic device (1) for controlling a key of a keyboard with which an electronic musical instrument is equipped, said device being associated with a key (K) mounted so as to be able to pivot with respect to a frame, the key extending in a longitudinal direction and having an angular movement between a high angular position, and a low angular position, characterized in that said device comprises: - means (30) for detecting the dynamic state of the key, - computing means for computing, depending on the dynamic information, an instantaneous resistive force to be exerted on said key in response to a depression of said key, - a rotary electrical actuator (10), - mechanical linking means (20) placed between the actuator and the key so as to apply, to said key, said resistive force, comprising at least one element that flexes under pressure and stiffens under traction.

IPC Classes  ?

• G10H 1/34 - Switch arrangements, e.g. keyboards or mechanical switches specially adapted for electrophonic musical instruments

Abstract

0a1234145 231424246271424248,9101111 are, independently, H, OH or protected OH. The present invention further relates to the method of preparation thereof, the intermediates thereof and the therapeutic applications thereof.

IPC Classes  ?

• C07D 493/04 - Ortho-condensed systems
• A61P 31/12 - Antivirals
• A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom

Abstract

Novel compounds derived from schweinfurthins G, E and F The present invention relates to novel compounds derived from schweinfurthins of formula (I): (I). The invention also relates to pharmaceutical compositions containing them and also to the use thereof for the prevention, inhibition and/or treatment of cancers, neurodegenerative diseases, dyslipidaemia, hypercholesterolaemia, parasitic diseases and/or viral diseases and to processes for preparing them.

IPC Classes  ?

• A61P 3/04 - Anorexiants; Antiobesity agents
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 31/14 - Antivirals for RNA viruses
• A61P 35/00 - Antineoplastic agents
• C07D 311/82 - Xanthenes
• C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 407/10 - Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
• C07D 493/04 - Ortho-condensed systems
• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
• A61K 31/4192 - 1,2,3-Triazoles

Abstract

The invention relates to an optical writing method in a semiconductor material (10), the method comprising laser writing in volume of the semiconductor material. The method comprises, prior to laser writing, irradiating the semiconductor material (10) with at least one laser pre-pulse configured to change transiently and locally one property of the semiconductor material (10).

IPC Classes  ?

• B23K 26/0622 - Shaping the laser beam, e.g. by masks or multi-focusing by direct control of the laser beam by shaping pulses
• B23K 26/06 - Shaping the laser beam, e.g. by masks or multi-focusing
• B23K 26/082 - Scanning systems, i.e. devices involving movement of the laser beam relative to the laser head
• B23K 26/352 - Working by laser beam, e.g. welding, cutting or boring for surface treatment
• B23K 26/402 - Removing material taking account of the properties of the material involved involving non-metallic material, e.g. isolators
• G11B 7/0045 - Recording
• B23K 101/40 - Semiconductor devices
• B23K 103/00 - Materials to be soldered, welded or cut

Abstract

λορορ ncpcp tcpcp λορορ ορ so as to allow coupling of the radiation guided by the first optical fibre towards the second optical fibre and/or from the second optical fibre towards the first optical fibre.

IPC Classes  ?

• G02B 6/02 - Optical fibres with cladding
• G02B 6/28 - Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals
• G02B 6/032 - Optical fibres with cladding with non-solid core or cladding

Abstract

The invention relates to a method for determining the state of the mechanical properties of a bonded assembly of materials by applying a local heat source that excites particles comprised within the adhesive and investigating the effect of this excitation on the mechanical properties of the adhesive by high-frequency electromagnetic imaging.

IPC Classes  ?

• G01N 23/04 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material
• C09J 5/00 - Adhesive processes in general; Adhesive processes not provided for elsewhere, e.g. relating to primers

Abstract

The present invention concerns a new method for the preparation of a Li-P-S-O product, as well as the products obtainable by said methods, and uses thereof especially as solid electrolytes.Figure: non

IPC Classes  ?

• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 10/052 - Li-accumulators
• H01M 10/0562 - Solid materials
• C01B 17/22 - Alkali metal sulfides or polysulfides
• C01B 25/14 - Sulfur, selenium, or tellurium compounds of phosphorus

Abstract

The invention relates to a method (200) for converting an initial datum (202) between a colour space (204) of a first colorimetric system and a colour space (206) of a second colorimetric system, said initial datum (202) being formed of at least one element expressed in a colorimetric reference system, said method (200) comprising the following steps: converting (208) said initial datum (202) into a projected datum (210), by expressing the at least one element (202) in the colour space (204) of the first colorimetric system; adapting (212) the projected datum (210) into an adapted datum (214), by expressing the at least one element in the colour space (206) of the second colorimetric system, characterized in that the colour space (204, 206) of the first colorimetric system and of the second colorimetric system are each a hyperbolic space (204, 206) defined by a hyperbolic metric projective reference system.

IPC Classes  ?

• G09G 5/02 - Control arrangements or circuits for visual indicators common to cathode-ray tube indicators and other visual indicators characterised by the way in which colour is displayed

Abstract

222 nanoparticles.

IPC Classes  ?

• C10M 125/22 - Compounds containing sulfur, selenium or tellurium
• C10M 171/06 - Particles of special shape or size
• C10M 173/02 - Lubricating compositions containing more than 10% water not containing mineral or fatty oils
• C10N 10/12 - Groups 6 or 16
• C10N 20/06 - Particles of special shape or size
• C10N 30/06 - Oiliness; Film-strength; Anti-wear; Resistance to extreme pressure
• C10N 40/02 - Bearings
• C10N 40/04 - Oil-bath; Gear-boxes; Automatic transmissions; Traction drives

Abstract

The present invention relates to a process for preparing at least one schweinfurthin chosen from schweinfurthin G of formula (SW-G), schweinfurthin K of formula (SW-K) and schweinfurthin R of formula (SW-R), characterized in that it comprises a step of using mappain of formula (IV).

IPC Classes  ?

• C07D 311/58 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulfur atoms in position 2 or 4
• C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans
• C07D 303/24 - Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Abstract

The invention relates to a method for treating an individual afflicted by a multiple myeloma by a composition comprising at least one G-quadruplex (G4) stabilizer.

IPC Classes  ?

• A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
• A61K 31/4045 - Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
• A61K 31/5517 - 1,4-Benzodiazepines, e.g. diazepam condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
• A61P 35/00 - Antineoplastic agents
• A61K 31/41 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
• A61K 31/47 - Quinolines; Isoquinolines
• A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
• A61K 31/4353 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems

Abstract

The present invention relates to a method for monitoring a system, comprising the following steps: i. obtaining timeseries describing the temporal evolution of a parameter of a system between an initial time and a final time, the final time being triggered by the occurrence of an abnormal event affecting the system, ii. for each timeseries, defining an abnormal time period and a normal time period, iii. for each timeseries, determining a metric characterizing each parameter of the series under consideration over the abnormal time period and over the normal time period, iv. determining association rules on the basis of the obtained characterizing metrics, v. validating the obtained association rules, and vi. predicting the occurrence or lack of occurrence of an abnormal event liable to affect a system to be monitored on the basis of the validated association rules.

IPC Classes  ?

• G05B 19/042 - Programme control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
• G05B 23/02 - Electric testing or monitoring

Abstract

The invention relates to a method for imaging an object to be imaged (O), characterised in that it comprises: - generating, by a lighting device (2), a series of lighting patterns; - for each lighting pattern, performing a simulation phase, wherein translations of the lighting pattern are performed at the input of a multimode optical fibre having a square cross-section (4) by means of at least one translation device (3a) of an optical system (3) arranged between the lighting device (2) and the input of the multimode optical fibre having a square cross-section (4), the translations being performed in a plane parallel to the input plane of the multimode optical fibre having a square cross-section (4); - for each simulation phase, performing an acquisition phase, wherein the signal generated by the lighting pattern on the object to be imaged (O) located at the output of the multimode optical fibre having a square cross-section (4) is measured by a signal measuring device (5; 9); and - reconstructing, by a computing device (6), using the measured signal for each of the acquisition phases, the object to be imaged (O).

IPC Classes  ?

• A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor

Abstract

A system (1) for generating signals intended for educational tests comprising generating means (20) for generating a signal (63) corresponding to a digital command (61) and to parameters contained in the digital command, and to transmit the signal to a measuring apparatus (30), the digital command being generated by command means (10) that are remote from the generating means, wherein at least one of the parameters comprises a random component.

IPC Classes  ?

• G09B 7/00 - Electrically-operated teaching apparatus or devices working with questions and answers
• G09B 7/08 - Electrically-operated teaching apparatus or devices working with questions and answers of the multiple-choice answer type, i.e. where a given question is provided with a series of answers and a choice has to be made from the answers characterised by modifying the teaching programme in response to a wrong answer, e.g. repeating the question, supplying further information
• G09B 5/08 - Electrically-operated educational appliances providing for individual presentation of information to a plurality of student stations
• G01R 13/00 - Arrangements for displaying electric variables or waveforms

Abstract

The invention relates to a pancreatic cell receiving matrix (1) comprising a semi-permeable wall (10) and a porous body (12) comprising a first set (120) of cavities (1200) comprising pancreatic cells (13), and a second set (121) of cavities (1210) free of pancreatic cells. The first set (120) of cavities and the second set (121) of cavities are not fluidically connected to one another. The cavity or cavities (1210) left free of cells create paths for the nutrients and gases to diffuse in the matrix (1), and they form a nutrient and gas reserve area in the matrix. The matrix (1) limits and preferably prevents nutrient and gas depletion of the pancreatic cells (13). Their mortality is therefore reduced, allowing better insulin delivery.

IPC Classes  ?

• A61F 2/02 - Prostheses implantable into the body

Abstract

The present invention relates to a lubricating composition comprising: - water, especially purified water, for example ultrapure water, demineralized water, osmotic water, deionized water; - glycerol; - nanosheets of h- MoS2, wherein the active content of h-MoS2 nanosheets is comprised between 0.01 and 0.07 wt%, preferably between 0.02 to 0.06 wt%, based on the total weight of the lubricating composition, - wherein, the nanosheets of h-MoS2 are obtained in-situ in the lubricating composition by liquid-phase exfoliation of bulk MoS2 particleswater

IPC Classes  ?

• C10M 125/22 - Compounds containing sulfur, selenium or tellurium
• C10M 129/14 - Hydroxy compounds having hydroxy groups bound to a carbon atom of a six-membered aromatic ring containing at least 2 hydroxy groups
• C10M 171/06 - Particles of special shape or size
• C10M 173/02 - Lubricating compositions containing more than 10% water not containing mineral or fatty oils
• C10N 10/12 - Groups 6 or 16
• C10N 20/06 - Particles of special shape or size
• C10N 30/06 - Oiliness; Film-strength; Anti-wear; Resistance to extreme pressure
• C10N 40/04 - Oil-bath; Gear-boxes; Automatic transmissions; Traction drives

Abstract

The invention relates to an optoelectronic component (1) that is insensitive to dislocations, comprising: - a semiconductor heterostructure (2) able to emit laser radiation, said semiconductor heterostructure being formed from first semiconductors comprising a cascade of gain-providing active regions (21) in which the inter-band radiative transition is of type II, and - a carrier structure (30) comprising a non-native substrate (3) different from the first semiconductors, said semiconductor heterostructure (2) being formed by epitaxial growth on the carrier structure (30), wherein the active regions have a dislocation density higher than 107.cm-2. Figure for the abstract: Fig. 1

IPC Classes  ?

• H01S 5/34 - Structure or shape of the active region; Materials used for the active region comprising quantum well or superlattice structures, e.g. single quantum well [SQW] lasers, multiple quantum well [MQW] lasers or graded index separate confinement heterostructure [GRINSCH] lasers
• H01S 5/02 - Structural details or components not essential to laser action

Abstract

The invention relates to a nickel-based superalloy comprising in weight percentages: 5.0 to 6.0% of aluminium, 6.0 to 9.0% of tantalum, 1.0 to 5.0% of cobalt, 5.0 to 7.5% of chromium, 0 to 1.0% of molybdenum, 4.0 to 6.0% of tungsten, 0.50 to 3.5% of rhenium, 1.0 to 4.0% of platinum, 0.05 to 0.25% of hafnium, 0 to 0.15% of silicon, the remainder consisting of nickel and unavoidable impurities. The invention also relates to a single-crystal blade (20A, 20B) comprising such an alloy and to a turbomachine (10) comprising such a blade (20A, 20B).

IPC Classes  ?

• C22C 19/05 - Alloys based on nickel or cobalt based on nickel with chromium
• F01D 5/28 - Selecting particular materials; Measures against erosion or corrosion

Abstract

ncc xyy n ∈ Nnss ncc ss nextext ncc nextext ext > 1 and adapted to the index of the exit medium and the index of the concentrator to limit the loss in light extraction efficiency of the exit beam induced by the cooling medium.

IPC Classes  ?

• H01L 25/075 - Assemblies consisting of a plurality of individual semiconductor or other solid state devices all the devices being of a type provided for in the same subgroup of groups , or in a single subclass of , , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group
• H01L 33/64 - Heat extraction or cooling elements
• H01L 33/50 - Wavelength conversion elements

Abstract

The present invention relates to a method for coating at least one fiber (11) with a boron nitride interphase, comprising treating said at least one fiber with a treatment medium (22) containing borazane and having a temperature of 100°C or higher and a pressure of 1 bar or higher.

IPC Classes  ?

• C04B 35/628 - Coating the powders
• D01D 5/00 - Formation of filaments, threads, or the like
• D01F 1/00 - General methods for the manufacture of man-made filaments or the like

Abstract

The present invention relates to a tactile stimulation interface (10), comprising a tactile face and a second face (8) equipped with at least one actuator (1a, 1b, 1c, 1d), the interface (10) being characterized in that the second face (8) comprises at least one acoustic wave confinement area (11), the confinement area (11) being defined by at least one acoustic mirror (9) made of an acoustic metamaterial configured to reflect acoustic waves of frequencies within a predetermined interval, called the band gap, the interface (10) furthermore being characterized in that each acoustic mirror (9) and each actuator (1a, 1b, 1c, 1d) comprises a system configured to generate and transmit acoustic waves to the tactile face (7) and to prevent the propagation of acoustic waves of frequencies within the band gap.

IPC Classes  ?

• G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer

Abstract

The invention relates to a method for characterizing a mechanical component to enable evaluation of the residual stresses in the component, and to a method for constructing a predictive model and to a nondestructive testing method allowing such a component to be tested easily, the characterization method comprising the following steps: the measuring of geometric information (21) about the component in a first state (20a), the physical transformation (22) of the component between the first state (20a) and a second state (20b), the measuring of geometric information (23) about the component in its second state (20b), the determining of the displacement field (24) for displacement between the first state (20a) and the second state (20b) of the component using a digital image correlation method, and the obtaining of the deformation field for deformation of the component between the first state (20a) and the second state (20b), and the determining of the stress field (25) of the component in the second state using a finite element simulation method.

IPC Classes  ?

• G01L 5/00 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes
• G01M 5/00 - Investigating the elasticity of structures, e.g. deflection of bridges or aircraft wings
• G01M 11/08 - Testing mechanical properties
• G01M 15/14 - Testing gas-turbine engines or jet-propulsion engines
• G01L 1/24 - Measuring force or stress, in general by measuring variations of optical properties of material when it is stressed, e.g. by photoelastic stress analysis

Abstract

The invention relates to a method for treating at least one silicon carbide fibre (16) comprising a surface layer containing carbon and/or a silicon oxycarbide, wherein the treatment comprises at least removing the surface layer from the fibre by contacting with an ammonia phase (22) in the supercritical state.

IPC Classes  ?

• C04B 35/80 - Fibres, filaments, whiskers, platelets, or the like
• C04B 41/53 - After-treatment of mortars, concrete, artificial stone or ceramics; Treatment of natural stone involving the removal of part of the materials of the treated article

Abstract

The present invention relates to an interface (1) for delivering tactile stimulation, comprising a first face (3), intended to be explored by touch, and called the tactile face, and a second face (4) provided with at least one actuator (5), said at least one actuator (5) being configured to be excited so as to generate and transmit acoustic waves to the tactile face, the interface (1) being characterized in that the second face (4) comprises at least one zone (7) for confining acoustic waves generated by said at least one actuator (5), said at least one confining zone (7) being delineated at least partially by acoustic mirrors (6) formed from an acoustic metamaterial configured to reflect acoustic waves of frequencies comprised in a predetermined interval, called the band gap, said band gap including the carrier frequency of the acoustic waves generated by said at least one actuator (5).

IPC Classes  ?

• G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer

Abstract

The present invention relates to a composition comprising a matrix and a carrier encapsulating a therapeutic compound, wherein the matrix is configured to release the therapeutic compound under an ultrasound stimulus.

IPC Classes  ?

• A61L 15/28 - Polysaccharides or their derivatives
• A61L 15/42 - Use of materials characterised by their function or physical properties
• A61L 15/44 - Medicaments
• A61L 15/60 - Liquid-swellable gel-forming materials, e.g. super-absorbents

Abstract

The present invention relates to a combination comprising at least one monoamine reuptake inhibitor and at least one potassium-chloride cotransporter type 2 expression-enhancing compounds (KEEC). The present invention also relates to a pharmaceutical composition comprising at least one monoamine reuptake inhibitor and at least one KEEC, and to a kit of parts comprising at least one monoamine reuptake inhibitor and at least one KEEC, as a combined preparation for simultaneous, separate or sequential use.

IPC Classes  ?

• A61K 31/138 - Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
• A61K 31/501 - Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
• A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 25/02 - Drugs for disorders of the nervous system for peripheral neuropathies
• A61P 29/02 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
• A61K 31/135 - Amines, e.g. amantadine having aromatic rings, e.g. methadone
• A61K 31/381 - Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
• A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
• A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Abstract

The present invention relates to a composition comprising: - either at least ethyl-β-D-glucuronide, the ethyl part of which comprises at least one non-radioactive isotope (or ethyl-β-D-glucuronide probe) and at least ethyl-β-D-galactopyranoside (or ethyl-β-D-galactopyranoside probe), the ethyl part of which comprises at least one non-radioactive isotope; - or at least ethyl-α-mannopyranoside, the ethyl part of which comprises at least one non-radioactive isotope (or ethyl-β-D-glucuronide probe); for use thereof as a diagnostic and/or prognostic agent.

IPC Classes  ?

• G01N 33/574 - Immunoassay; Biospecific binding assay; Materials therefor for cancer
• C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase

Abstract

The present invention discloses novel synthetic peptides that are inhibitors of c-Fos phosphorylation by ERK1/2 kinases. The invention also relates to a pharmaceutical composition containing said peptides and to the use thereof as active ingredients. A method for identifying novel inhibitors of c-Fos phosphorylation by ERK1/2 is also disclosed.

IPC Classes  ?

• C07K 14/82 - Translation products from oncogenes

Abstract

The present invention discloses novel synthetic peptides that are inhibitors of Elk-1 phosphorylation by ERK1/2 kinases. The invention also relates to a pharmaceutical composition containing said peptides and to the use thereof as medicaments. A method for identifying and optimising novel inhibitors of Elk-1 phosphorylation by ERK1/2 is also disclosed.

IPC Classes  ?

• C07K 14/82 - Translation products from oncogenes

Abstract

One aspect of the invention relates to an automatic method for characterizing a recycled granulate obtained by crushing building materials, comprising the following steps: - performing supervised training of a convolutional neural network in order to make it capable of delivering, on the basis of a granulate image, a class, an area and a mass of the granulate, comprising: - a base module; - a classification module connected to the base module, delivering a class; - a geometric module connected to the base module, comprising a first sub-module delivering a first factor and a second sub-module delivering a second factor corresponding to an area; - a density module connected to the base module, delivering a third factor, the product of the first factor, of the second factor and of the third factor corresponding to a mass; using, on an image of the granulate to be characterized, the trained convolutional neural network to obtain the class, area and mass of the granulate to be characterized.

IPC Classes  ?

• G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
• G06V 10/141 - Control of illumination
• G06V 10/32 - Normalisation of the pattern dimensions
• G06V 10/26 - Segmentation of patterns in the image field; Cutting or merging of image elements to establish the pattern region, e.g. clustering-based techniques; Detection of occlusion
• G06V 10/44 - Local feature extraction by analysis of parts of the pattern, e.g. by detecting edges, contours, loops, corners, strokes or intersections; Connectivity analysis, e.g. of connected components

Abstract

Optimized light emitting device Light emitting device (1) comprising a solid fluorescent material or a solid scintillator material (CL) adapted to absorb an incident light (Ld) and then emit a luminescent light (LL) in said material, a portion, called trapped portion (Lp), of said luminescent light being trapped by total internal reflections in said material, said material comprising two parallel faces, called large faces (FE1, FE2), along an horizontal plane xy, and n EN>2 faces called side faces (FL1, FL2, FL3, F4), and forming vertex (S2, S3, S4) between two adjacent side faces and a large face, wherein said material has an invariance of the normals to said side faces by rotation by an angle of 2-n7n in said horizontal plan around a z-axis perpendicular to said horizontal plane, wherein said material has a vertex called virtual vertex (SI) that is beveled thus forming a surface called beveled vertex (SB1), or wherein said material has an edge between two side faces, called virtual edge (S1S5), that is beveled thus forming a surface beveled edge (SB1), a portion of the rays of said trapped portion passing through said beveled surface thus forming an exit beam (LS), wherein a normal (n " *) to said beveled vertex is parallel to the sum of the normal of the faces forming said virtual surface, within±10°.

IPC Classes  ?

• H01L 33/50 - Wavelength conversion elements
• G01T 1/20 - Measuring radiation intensity with scintillation detectors
• H01L 25/075 - Assemblies consisting of a plurality of individual semiconductor or other solid state devices all the devices being of a type provided for in the same subgroup of groups , or in a single subclass of , , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group

Abstract

It is provided a method for enhancing the photoresistance of a fluorescent protein when used in fluorescence microscopy of a sample (2) containing several molecules of the fluorescent protein according to a fluorescence microscopy technique, the method comprising illuminating at least partially the sample with an exciting light beam (4) and illuminating at least partially the same region of the sample with an enhancing light beam (6). It is also provided a fluorescence microscopy system (1) suitable to implement the above method.

IPC Classes  ?

• G01N 21/64 - Fluorescence; Phosphorescence

Abstract

The invention relates to a vial (100) for the cryopreservation of multiple biological samples. This vial (100) comprises: a container (110), made in one piece, defining an inner volume (112) and an opening provided with a thread (132); and a threaded cap (150), which cooperates with the thread (132) of the opening so as to selectively close the inner volume (112), in a sealed configuration of the vial (100), or allow the access to the inner volume (112), in an unsealed configuration of the vial (100). According to the invention, the container (110) includes at least one inner partition (124), configured to divide the inner volume (112) in at least two separated chambers (126), each chamber (126) being accessible from the opening (114). Each chamber is configured to receive one biological sample. The vial according to the invention is easy to handle and space-saving. Also disclosed is a mounting base comprising at least one recessed reception volume that is configured to receive such a vial.

IPC Classes  ?

• A01N 1/02 - Preservation of living parts
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
• B01L 9/06 - Test-tube stands; Test-tube holders
• B01L 7/00 - Heating or cooling apparatus; Heat insulating devices

Abstract

The present disclosure relates to a wireless communication device for a wireless communication with two or more second wireless communication devices. The wireless communication device is configured to, for a channel between the wireless communication device and a respective second wireless communication device, initialize, based on a respective channel impulse response of the channel, a respective precoder for precoding a signal intended for the respective second communication device; determine one or more respective interference peaks caused at the respective second wireless communication device and/or at one or more other second wireless communication devices by transmitting a respective signal intended for the respective second wireless communication device and precoded by the respective precoder; select an interference peak fulfilling a criterion among the determined one or more respective interference peaks; and update, based on the selected interference peak, the respective precoder, which precodes the respective signal that causes the selected interference peak.

IPC Classes  ?

• H04L 25/02 - Baseband systems - Details
• H04L 25/03 - Shaping networks in transmitter or receiver, e.g. adaptive shaping networks

Abstract

The present invention relates to a method P1 for converting osmotic energy into hydraulic energy and P2 for desalination, comprising the steps of pressurisation/depressurisation and isochoric washing of an aqueous solution comprising a salt in the presence of a selective hydrophobic nanoporous material of which the nanoporous volume within the material is only accessible to fresh water and which has a nanoporosity volume fraction ranging from 0.2 to 1 so as to convert osmotic energy into hydraulic energy or conversely to desalinate water, preferably sea water or brine.

IPC Classes  ?

• F03G 7/00 - Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor

Abstract

The invention relates to a fenestrated endoprosthesis of the thoracic aorta comprising a first mesh of stents (2), a main tubular endoprosthesis (1) made of fabric, the main tubular endoprosthesis being rigidly attached to the first mesh, and having an arcuate central portion (12) configured to be received in the aortic arch of a patient, the arcuate central portion extending between a first (10) and a second (11) end, each configured to be received respectively in a portion of the ascending or descending aorta, respectively, the fenestrated endoprosthesis further comprising a flange (3) also made of fabric and associated with a second mesh of stents (4), the flange having a substantially frustoconical shape and having a base (30), the base of the flange being mounted on an opening (13) made in the upper face of the arcuate central portion (12), the flange (3) being configured to be received at the base of the supra-aortic trunks of the patient.

IPC Classes  ?

• A61F 2/07 - Stent-grafts

Abstract

The present invention relates to the use of CASD1 as a biomarker of a cancer expressing the O-acetylated-GD2 ganglioside. The present invention further concerns a method of diagnosing a cancer expressing the O-acetylated-GD2 ganglioside, a method of selecting a subject suffering from a cancer expressing the O-acetylated-GD2 ganglioside for treatment targeting said cancer, or a method of monitoring the response of a subject suffering from a cancer expressing the O-acetylated-GD2 ganglioside to a treatment targeting said cancer.

IPC Classes  ?

• G01N 33/574 - Immunoassay; Biospecific binding assay; Materials therefor for cancer

Abstract

The present invention relates to novel short antimicrobial peptides derived from SHf, to pharmaceutical compositions comprising said peptides and to the uses thereof, in particular as medicament, disinfectant, preservative, agent preventing biofilm formation or pesticide.

IPC Classes  ?

• C07K 14/46 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans from vertebrates
• C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• A61K 38/00 - Medicinal preparations containing peptides

Abstract

The invention relates to a substrate coated with a coating consisting of molybdenum (Mo) atoms, sulfur (S) atoms, tantalum (Ta) atoms and oxygen (O) atoms present in the form of one or more compounds chosen from the compounds of formula (I): [Chem 16] MowSxTayOz (I) in which w is equal to 0 or 1; x ranges from 0 to 2; y ranges from 0 to 1 and z ranges from 0 to 3; said coating comprising at least 5 at.% of oxygen and said coating having a dense compact microstructure.

IPC Classes  ?

• C23C 14/00 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
• C23C 14/06 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
• C23C 14/08 - Oxides
• C23C 14/34 - Sputtering
• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering

Abstract

The present invention relates to a masterbatch comprising at least one thermoplastic polymer and at least one ionene polymer, as well as to the production method thereof. The present invention also relates to the use of such a masterbatch for producing an article having bacteriostatic or bactericidal properties.

IPC Classes  ?

• C08J 5/18 - Manufacture of films or sheets
• C08L 23/06 - Polyethene

Abstract

The present invention relates to a method and a kit for determining if a patient having pancreatic ductal adenocarcinoma (PDAC) is sensitive to a treatment. It further relates to a method for determining a suitable treatment for a patient having PDAC.

IPC Classes  ?

• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Abstract

The invention relates to an in vitro method for determining whether a sample contains a replicating virus, said method comprising detecting Papain-like protease activity (PLpro) of the virus.

IPC Classes  ?

• C12Q 1/37 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
• G01N 33/58 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Abstract

The invention relates to a head for the chemical vapor deposition of a tubular substrate, comprising: - a first opening for receiving a first precursor, - a second opening for receiving a second precursor, - a third opening for receiving an inert gaseous stream, - a first network of distribution ducts connecting the first opening to a first group of orifices extending over an internal section of the head, - a second network of distribution ducts connecting the second opening to a second group of orifices extending over at the internal section of the head, - a third network of distribution ducts connecting the third opening to a third group of orifices extending over the internal section of the head, an orifice of the first or second group of orifices being adjacent on either side to an orifice of the third group of orifices, the first, second and third networks of distribution ducts respectively having at least a first, second and third expansion pre-chamber, the tubular substrate performing a back-and-forth relative movement.

IPC Classes  ?

• C23C 16/40 - Oxides
• C23C 16/44 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition (CVD) processes characterised by the method of coating
• C23C 16/455 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition (CVD) processes characterised by the method of coating characterised by the method used for introducing gases into the reaction chamber or for modifying gas flows in the reaction chamber
• C23C 16/54 - Apparatus specially adapted for continuous coating
• B33Y 80/00 - Products made by additive manufacturing
• B33Y 10/00 - Processes of additive manufacturing

Abstract

mbarθii nn mbarmbar within the detection enclosure.

IPC Classes  ?

• G01N 23/201 - Measuring small-angle scattering, e.g. small angle X-ray scattering [SAXS]
• H05H 3/02 - Molecular or atomic-beam generation, e.g. resonant beam generation
• G01N 23/207 - Diffractometry, e.g. using a probe in a central position and one or more displaceable detectors in circumferential positions
• H01L 21/302 - Treatment of semiconductor bodies using processes or apparatus not provided for in groups to change the physical characteristics of their surfaces, or to change their shape, e.g. etching, polishing, cutting
• H01J 37/32 - Gas-filled discharge tubes
• H01J 37/34 - Gas-filled discharge tubes operating with cathodic sputtering

Abstract

ABABB are configured such that the residence time in the reaction tube is less than or equal to 10 seconds, wherein the pH in the reaction tube is 7 to 12 and wherein the state in the reaction tube is a laminar state.

IPC Classes  ?

• C01G 53/00 - Compounds of nickel
• H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
• H01M 10/052 - Li-accumulators
• H01M 10/0569 - Liquid materials characterised by the solvents
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

16166)alkyl; and R2 is an optionally substituted heteroaryl group, as well as processes for the preparation of said compound, and intermediate compounds.

IPC Classes  ?

• C07D 213/36 - Radicals substituted by singly-bound nitrogen atoms
• C07C 43/225 - Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
• C07D 213/50 - Ketonic radicals
• C07D 213/61 - Halogen atoms or nitro radicals
• C07D 213/64 - One oxygen atom attached in position 2 or 6
• C07D 215/14 - Radicals substituted by oxygen atoms
• C07D 239/26 - Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
• C07D 239/28 - Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
• C07D 239/30 - Halogen atoms or nitro radicals
• C07D 239/34 - One oxygen atom
• C07D 307/46 - Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
• C07D 333/16 - Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
• C07D 333/22 - Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
• C07D 213/73 - Unsubstituted amino or imino radicals
• C07D 239/42 - One nitrogen atom
• C07D 277/64 - Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
• C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

A portable imaging system (10) for viewing a target biological structure (100) by means of a monitoring element introduced into therein, the portable imaging system comprising: - a control unit (20) with a memory (22) for storing at least one ultrasound image (16) of the target structure, - a probe (24) to be removably attached to a biological attachment structure (200) that at least partially surrounds the target structure, the probe being connected to the control unit, - a module (26) to assist with the positioning of the probe. The probe is capable of detecting the monitoring element by means of ultrasound, the control unit thus being capable of locating the monitoring element in real time within the target structure so as to geometrically characterise the target structure and create the ultrasound image. The control unit can also display the image on a display device (18). The ultrasound image enables a rapid diagnosis to be made, irrespective of the location and the environment.

IPC Classes  ?

• A61B 8/08 - Detecting organic movements or changes, e.g. tumours, cysts, swellings
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves

Abstract

The invention relates to a method for manufacturing an abradable layer and a substrate coated with this layer, comprising the following steps: preparing a powder composition (30) comprising at least ceramic particles and an inorganic filler having a lamellar crystallographic structure, the volume content of the inorganic filler in the powder composition being between 1 and 75%; compressing the powder composition (30); and sintering the powder composition (30) thus compressed in order to obtain the abradable layer (12).

IPC Classes  ?

• C04B 35/447 - Shaped ceramic products characterised by their composition; Ceramic compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on phosphates
• C04B 35/486 - Fine ceramics
• C04B 35/488 - Composites
• C04B 35/622 - Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
• C04B 35/626 - Preparing or treating the powders individually or as batches
• C04B 35/645 - Pressure sintering
• C04B 37/00 - Joining burned ceramic articles with other burned ceramic articles or other articles by heating
• C04B 37/02 - Joining burned ceramic articles with other burned ceramic articles or other articles by heating with metallic articles
• C04B 41/00 - After-treatment of mortars, concrete, artificial stone or ceramics; Treatment of natural stone
• C04B 41/52 - Multiple coating or impregnating
• C04B 41/89 - Coating or impregnating for obtaining at least two superposed coatings having different compositions
• C23C 24/08 - Coating starting from inorganic powder by application of heat or pressure and heat
• C04B 38/00 - Porous mortars, concrete, artificial stone or ceramic ware; Preparation thereof
• F01D 11/12 - Preventing or minimising internal leakage of working fluid, e.g. between stages for sealing space between rotor blade tips and stator using a rubstrip, e.g. erodible, deformable or resiliently biased part
• C23C 24/04 - Impact or kinetic deposition of particles
• C23C 24/00 - Coating starting from inorganic powder
• C04B 111/00 - Function, property or use of the mortars, concrete or artificial stone

Abstract

252252233. The invention also relates to a method for determining the reflective portion of a daytime radiative cooling device. Finally, the invention relates to a method for determining the emitting portion of a daytime radiative cooling device.

IPC Classes  ?

• C03C 17/34 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with at least two coatings having different compositions
• F25B 23/00 - Machines, plants or systems, with a single mode of operation not covered by groups , e.g. using selective radiation effect
• G02B 5/20 - Filters
• G02B 5/26 - Reflecting filters

Abstract

The present invention relates to a catalyst of Formula (I) wherein R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, L1, M1, Q1, and Q2 have the meaning defined in the description and claims. The present invention also relates to a catalyst composition comprising at least one catalyst according to the invention, an optional activator; an optional support; and an optional co-catalyst. The present invention also relates to the use of a catalyst or catalyst composition according to the invention for the preparation of an olefin polymer. The present invention also relates to an olefin polymerization process, the process comprising: contacting a catalyst or a catalyst composition according to the invention, with an olefin monomer, optionally hydrogen, and optionally one or more olefin comonomers; polymerizing the monomer, and the optionally one or more olefin comonomers, in the presence of the at least one catalyst composition, and optional hydrogen, thereby obtaining an olefin polymer. The present invention also relates to olefin polymers and articles comprising said olefin polymer.

IPC Classes  ?

• C08F 4/00 - Polymerisation catalysts
• C08F 110/00 - Homopolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
• C07F 17/00 - Metallocenes

Abstract

Flexible surgical device with controllable stiffness The invention relates to a surgical device (10), comprising a tubular outer shaft (12,) and an inner element (14) having an elongated shape, the outer shaft comprising a distal (30a) and a proximal (30b) outer hinges, the inner element comprising an inner hinge (80), the surgical device having : a first and a second distal stiffnesses considered at the distal outer hinge; and a first and a second proximal stiffnesses considered at the proximal outer hinge; each of the second distal and proximal stiffnesses being superior to, respectively, the first distal and proximal stiffness; the inner element being able to move angularly and/or axially in the tubular outer shaft, between a first configuration and a second configuration, so that in the first configuration, the surgical device has the second distal stiffness and the first proximal stiffness.

IPC Classes  ?

• A61B 10/02 - Instruments for taking cell samples or for biopsy
• A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
• A61B 10/04 - Endoscopic instruments

Abstract

The present description relates to a three-dimensional imaging system (100) comprising a light source (110) configured to emit a beam of spatially incoherent light, having a given central length, configured to illuminate a biological sample (10) being transmitted; an optical imaging system (120) comprising a microscope lens (121) with a given object focal plane (125) near which the sample (10) is positioned; means for axially moving the microscope lens relative to the sample; a two-dimensional acquisition device (140) comprising a plurality of elementary detectors arranged in a detection plane (141) optically conjugate with the object focal plane and a processing unit (150). For each section of a biological object of the sample, a plurality of two-dimensional interferometric signals resulting from optical interference between the illumination beam and a beam scattered by an object field of the section are acquired and at least a first image is calculated from the plurality of two-dimensional interferometric signals.

IPC Classes  ?

• G01B 9/02055 - Reduction or prevention of errors; Testing; Calibration
• G01B 9/02091 - Tomographic interferometers, e.g. based on optical coherence
• G01B 9/02015 - Interferometers characterised by the beam path configuration

Abstract

AA, Nu, R1, R2, R3, and R4 are each independently an atom or a chemical group of atoms.

IPC Classes  ?

• C07D 215/42 - Nitrogen atoms attached in position 4
• C07D 215/48 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
• C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
• C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07F 7/08 - Compounds having one or more C—Si linkages
• C07F 11/00 - Compounds containing elements of Groups 6 or 16 of the Periodic System
• A61K 31/47 - Quinolines; Isoquinolines
• A61P 35/00 - Antineoplastic agents

Abstract

The invention relates to the design of a 3D capacitor comprising inter-digitated nanowires. The nanowires are electrodeposited in a conventional membrane. The electrodeposition is carried out using a mask that is also a membrane. The superposition of the two membranes allows nanowires to be grown in each channel formed by linking a pore of the object membrane with a pore of the mask membrane. By chance, only some of the pores of the object membrane form channels with pores of the mask membrane. The electrodeposition is stopped before the nanowires fill the object membrane. The mask is then removed. A gold film is then sputtered onto the face, which was free, of the object membrane. A second electrodeposition is carried out in the pores that were blocked beforehand by the mask. Once again, deposition is stopped before the nanowires fill the pores. Lastly, a gold film is sputtered onto the side that made contact with the mask.

IPC Classes  ?

• H01G 4/06 - Solid dielectrics
• H01G 11/24 - Electrodes characterised by the structural features of powders or particles used therefor

Abstract

This computer-implemented method allows assessing the shear elasticity modulus of a flexible tube, such as a blood vessel. In the field of medicine, this allows assessing whether a blood vessel is at risk of breakage or tearing. In the case of an artificial tube to be implanted in a patient's body, this allows verifying that this tube is compatible with the patient's body. The method includes the following further steps: a) obtaining (1002) a first dataset relating to spatiotemporal deformations of the tube; b) detecting and storing (1004) a wall inner surface of the tube and its diameter (D); c) identifying (1006) a number of transverse sections (Sij) of the tube; d) computing (1008) an average particle velocity (Vij) over each section; e) computing (1010) a wave propagation speed (C2) of an antisymmetric wave (W2); f) based on the wave propagation speed (C2) and on the diameter (D), assessing (1012) the shear elasticity modulus (μ) of the tube.

IPC Classes  ?

• A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
• A61B 3/12 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
• A61F 2/06 - Blood vessels

Abstract

The invention relates to a textile elementary monofilament consisting of a polyester, said textile elementary monofilament having a melting temperature Tf greater than or equal to 240°C, a tenacity greater than or equal to 2.5 cN/tex and an elongation at break greater than or equal to 10%, as well as to a method for producing such a monofilament.

IPC Classes  ?

• D01F 6/62 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters
• D01F 1/10 - Other agents for modifying properties
• C08G 63/672 - Dicarboxylic acids and dihydroxy compounds
• D01F 6/86 - Monocomponent man-made filaments or the like of synthetic polymers; Manufacture thereof from copolycondensation products from polyetheresters

Abstract

A method (50) for fabricating an asymmetric SOT-MRAM memory cell unit, said memory cell unit comprising a conductor track and a pad, arranged on the conductor track and comprising at least one first magnetic region with free magnetization, characterized in that it comprises the steps of: producing (100) a stack of a plurality of extended layers, comprising at least one first extended magnetic layer; depositing (200) a mask on an upper surface of the stack; and defining (400, 500) the first magnetic region in the first extended magnetic layer though ion irradiation of the upper surface of the stack carrying the mask, the parameters of the ion irradiation being adapted so as to modify magnetic properties of the material forming the first magnetic layer.

IPC Classes  ?

• H01L 43/12 - Processes or apparatus specially adapted for the manufacture or treatment of these devices or of parts thereof
• H01L 43/08 - Magnetic-field-controlled resistors
• H01L 27/22 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate using similar magnetic field effects
• G11C 11/16 - Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using magnetic elements using elements in which the storage effect is based on magnetic spin effect

Abstract

The present application relates to novel bifunctional PROTAC-type compounds simultaneously binding the target protein PXR and E3-ubiquitin ligase, to a method for preparing same, and to uses thereof for treating cancers overexpressing PXR.

IPC Classes  ?

• A61K 47/55 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
• A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
• C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• A61P 35/00 - Antineoplastic agents

Abstract

The invention relates to a process for preparing a microelectronic component, comprising a clean of the surface of an exposed layer based on a III-V material using a cyclic plasma treatment, each cycle comprising a purge phase and a plasma-treatment phase. During the formation of the plasma, a bias voltage Vbias-substrate is applied to the substrate. The process further comprises deposition, on the cleaned surface, of a subsequent layer. The process allows the exposed layer to be cleaned optimally while minimising, and preferably avoiding, any degradation of the structure. The preparing process thus allows the quality of the interface between the layer based on a III-V material and the subsequent layer to be improved. The electrical properties of the component are therefore improved.

IPC Classes  ?

• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
• H01L 21/28 - Manufacture of electrodes on semiconductor bodies using processes or apparatus not provided for in groups

Abstract

The invention relates to a magnetic handling device (1) designed for handling an object in a working space, the device (1) comprising: - a tubular housing (2) made of non-magnetic or weakly magnetic material, comprising at least two adjacent faces referred to as sliding faces (2a, 2b), a first end of the tubular housing (2) being open and in communication with the working space, - a ferromagnetic armature (5) arranged in the tubular housing (2) so as to slide along the longitudinal axis of the tubular housing (2), - a handling shaft (6) extending through the tubular housing (2), the handling shaft (6) being coupled to the ferromagnetic armature (5) so as to be able to slide towards or into the working space, - an actuator (7) arranged outside the tubular housing (2), comprising a plurality of magnets (8) forming a magnetic system (20) with the ferromagnetic armature (5), the actuator (7) being configured to make the ferromagnetic armature (5) slide along the longitudinal axis of the tubular housing (2), internal surfaces (9a, 9b) of the actuator (7) and external surfaces of the ferromagnetic armature (5) being configured to conform to the at least two sliding faces (2a, 2b), the ferromagnetic armature (5) being configured to be pressed against the at least two sliding faces (2a, 2b) of the tubular housing (2) by the magnets (8).

IPC Classes  ?

• C23C 16/458 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition (CVD) processes characterised by the method of coating characterised by the method used for supporting substrates in the reaction chamber
• H01L 21/677 - Apparatus specially adapted for handling semiconductor or electric solid state devices during manufacture or treatment thereof; Apparatus specially adapted for handling wafers during manufacture or treatment of semiconductor or electric solid state devices or components for conveying, e.g. between different work stations

Abstract

The invention relates to a device (10) comprising a first segment (15), a second segment (20), a first contact (25) and a second contact (30), the first segment (15) being made of a semiconductor having a first doping, the second segment (20) being made of a semiconductor having a second doping different from the first, the first segment (15) and the second segment (20) forming a p-n junction comprising a depletion region (70) in the first segment (15), the contacts (25, 30) being configured so that, when a voltage (V1) is applied across the contacts (25, 30), a dimension of the depletion region (70) depends on a value of the voltage, an ionisation energy being defined for dopants of the second segment (20). The device (10) comprises an emitter (40) that generates radiation having an energy higher than the ionisation energy and that irradiates the second segment (20) with the radiation.

IPC Classes  ?

• H01L 25/16 - Assemblies consisting of a plurality of individual semiconductor or other solid state devices the devices being of types provided for in two or more different main groups of groups , or in a single subclass of , , e.g. forming hybrid circuits
• H01L 33/62 - Arrangements for conducting electric current to or from the semiconductor body, e.g. leadframe, wire-bond or solder balls
• H01L 33/00 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof
• H01L 33/38 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the electrodes with a particular shape

Abstract

The present invention relates to a method for producing ammonia nitrogen, using dinitrogen reduction in the presence of a compound (I) comprising at least one element from group 13 of the periodic table of elements and of a reducing agent; and to the use of said compound (I) for the dinitrogen reduction.

IPC Classes  ?

• C01C 1/28 - Methods of preparing ammonium salts in general

Abstract

The present invention relates to the field of medicine. In particular, the invention relates to tenoxicam and its use in the treatment of proteinopathy of the central nervous system. More specifically, the present invention relates to tenoxicam compound for use in the treatment of an animal or human prion disease.

IPC Classes  ?

• A61K 31/542 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
• A61P 25/16 - Anti-Parkinson drugs
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

The present invention relates to the field of medicine. In particular, it relates to naloxone and its use in the treatment of proteinopathies of the central nervous system, in particular of the animal or human prion disease. The invention also relates to a pharmaceutical combination of naloxone and tenoxicam and its use in the treatment of proteinopathy of the CNS.

IPC Classes  ?

• A61K 31/485 - Morphinan derivatives, e.g. morphine, codeine
• A61K 31/542 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
• A61P 25/16 - Anti-Parkinson drugs
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

The invention relates to a method for recycling NdFeB magnets, comprising the following steps: a) recovering waste containing solid NdFeB magnets to be recycled; b) preheating the waste to a preheat temperature of between 300°C and 500°C under an inert atmosphere, in a first chamber raised to the preheat temperature in a first station equipped with heating means; c) decrepitating using hydrogen, this operation being applied to the hot waste from step b), in a second chamber positioned in a second station distinct from the first station and equipped with a source of hydrogen and with pumping means, the decrepitation being performed at a temperature of between 200°C and 500°C, said temperature in the second chamber being maintained in this temperature range as a result of the exothermal nature of the reaction of hydriding the NdFeB magnets, the step c) leading to the formation of a first powder with particles containing a main phase consisting of Nd2Fe14B and/or an inter-granule a secondary phase, and having a particle size less than or equal to 5 mm.

IPC Classes  ?

• C22B 59/00 - Obtaining rare earth metals
• C22B 7/00 - Working-up raw materials other than ores, e.g. scrap, to produce non-ferrous metals or compounds thereof
• C22C 1/04 - Making non-ferrous alloys by powder metallurgy
• H01F 1/053 - Alloys characterised by their composition containing rare earth metals
• H01F 1/057 - Alloys characterised by their composition containing rare earth metals and magnetic transition metals, e.g. SmCo5 and IIIa elements, e.g. Nd2Fe14B
• H01F 41/02 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformers; Apparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for manufacturing cores, coils or magnets
• B33Y 10/00 - Processes of additive manufacturing
• B22F 10/20 - Direct sintering or melting
• B33Y 80/00 - Products made by additive manufacturing

Abstract

The present invention relates to polymeric compounds of glucuronic acid having phenolic hydroxyl moieties (herein after designated by PGU-Ph) and more particularly to a method of hydrogelation of such compounds. The present invention also relates to the use of the hydrogel structures (particles, films or 3D-strucutres) obtained by this method, notably as three-dimensional cell culture material to support biological molecules used as active ingredients, cell colonisation or for tissue regeneration.

IPC Classes  ?

• C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
• A61L 27/52 - Hydrogels or hydrocolloids
• C08L 5/00 - Compositions of polysaccharides or of their derivatives not provided for in group or
• C08B 37/00 - Preparation of polysaccharides not provided for in groups ; Derivatives thereof
• C08B 37/08 - Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
• C08L 5/08 - Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
• A61K 47/36 - Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Abstract

Optoelectronic device for extracting characteristics contained in the spectrum of continuous or pulsed, noisy, analog radiofrequency signals, forming an analog input signal, the device comprising: - an input module generating an optical carrier wave (1) and performing a modulation of this carrier (1) by the analog input signal, to form a modulated optical signal; - a network (5) of linear optical cavities optically pumped and coupled by the modulated optical signal; - an optical device (7) for measuring the measured quantities of the optical fields, these optical fields being induced by the optical signal modulated by the analog input signal; - a calculation module (8) performing a linear transformation on the measured quantities of the optical fields, by multiplication with a matrix W and addition of a bias vector b; to make it possible to reconstruct and extract targeted characteristics contained in the spectrum of the radiofrequency input signal, the calculation module (8) having performed machine learning on noisy analog radiofrequency drive signals having the same targeted characteristics in order to determine the parameters W and b.

IPC Classes  ?

• G01R 23/17 - Spectrum analysis; Fourier analysis with optical auxiliary devices

Abstract

The present invention relates to a single domain antibody directed against H2AX with a phosphorylation of serine at position 139 (γ-H2AX), a bivalent molecule comprising said single domain antibody and their use for detecting DNA damage and/or DNA replication stress.

IPC Classes  ?

• C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
• G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor

Abstract

The invention relates to a prodrug formed from a compound comprising a pharmaceutically active antioxidant molecule which is covalently coupled, via a bond comprising at least one carboxylic ester group, to a nucleoside devoid of free hydroxyl and primary amine functions, comprising a ribose or deoxyribose unit covalently bonded to a nucleic base, this nucleoside bearing at least one lipidising group. A pharmaceutical composition which is particularly useful for therapeutic uses contains this prodrug in a nanoemulsion, in which the prodrug is contained in the lipophilic phase.

IPC Classes  ?

• A61K 31/7072 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/107 - Emulsions
• A61P 17/02 - Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• C07H 19/06 - Pyrimidine radicals

Abstract

The invention relates to a method for producing an NdFeB permanent magnet in the form of an object to be printed, the method comprising the following steps: a) providing an NdFeB alloy powder consisting of particles having a size of less than 300 microns, among which at least the particles having a size of greater than 5 microns are composed of a plurality of grains of an Nd2Fe14B magnetic main phase separated from one another by a non-magnetic inter-granular secondary phase rich in rare-earth elements, said grains having a common crystallographic orientation which generates magnetic anisotropy, the powder comprising between 10% and 50% by volume of inter-granular secondary phase, a') optionally adding particles of a third non-magnetic metal phase without any rare-earth elements, having a melting point below or equal to that of the inter-granular secondary phase, to the NdFeB alloy powder, in order to form a doped NdFeB alloy powder, b) additive manufacturing using the NdFeB alloy powder or the doped NdFeB alloy powder, by a technique involving melting at least one phase of the powder, for the production of the object to be printed, the melting being carried out at a temperature below the melting point of the main phase, so as to melt all or part of the inter-granular secondary phase and/or of the third phase when one is present, and not said main phase.

IPC Classes  ?

• B22F 1/00 - Metallic powder; Treatment of metallic powder, e.g. to facilitate working or to improve properties
• B22F 9/02 - Making metallic powder or suspensions thereof; Apparatus or devices specially adapted therefor using physical processes
• B22F 10/20 - Direct sintering or melting
• C22C 38/00 - Ferrous alloys, e.g. steel alloys
• H01F 1/057 - Alloys characterised by their composition containing rare earth metals and magnetic transition metals, e.g. SmCo5 and IIIa elements, e.g. Nd2Fe14B
• H01F 41/02 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformers; Apparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for manufacturing cores, coils or magnets
• C22B 7/00 - Working-up raw materials other than ores, e.g. scrap, to produce non-ferrous metals or compounds thereof
• C22B 7/02 - Working-up flue dust
• C22B 59/00 - Obtaining rare earth metals
• B33Y 10/00 - Processes of additive manufacturing
• B33Y 40/10 - Pre-treatment
• B22F 1/052 - Metallic powder characterised by the size or surface area of the particles characterised by a mixture of particles of different sizes or by the particle size distribution
• B22F 1/142 - Thermal or thermo-mechanical treatment
• B22F 9/04 - Making metallic powder or suspensions thereof; Apparatus or devices specially adapted therefor using physical processes starting from solid material, e.g. by crushing, grinding or milling

Abstract

The present invention relates to a self-healing composition comprising a commercial polyurethane thermoplastic polymer whose properties are modified, by exchange reactions with a second polyurethane thermoplastic polymer different from the commercial polymer or a second non-isocyanate polyurethane polymer.

IPC Classes  ?

• C08G 71/04 - Polyurethanes
• C08L 75/04 - Polyurethanes

Abstract

Waveplate (1), operating in transmission, for modifying a polarization state of electromagnetic radiation possessing a dominant wavelength, denoted λ, comprised between 200 nm and 400 nm; the waveplate (1) comprising: - a substrate (2) that is transparent to the electromagnetic radiation and that comprises first and second opposite surfaces (20, 21) that are intended to be successively passed through by the electromagnetic radiation, which is preferably incident at normal incidence, the second surface (21) being planar; - features (200) produced in a dielectric that is transparent to the electromagnetic radiation, the dielectric having a refractive index, denoted n, lower than or equal to 1.6 at the dominant wavelength, the features (200) forming a transmission grating in the first surface (20) of the substrate (2), the features (200) extending in a first longitudinal direction (X), the features (200) being spaced apart periodically in a second longitudinal direction (Y) perpendicular to the first longitudinal direction (X), and with a spatial period, denoted p, respecting p < λ, the features (200) having a height, denoted h, along the normal (Z) to the first surface (20) respecting h ≥ 3 p, the height of the features (200) being adjusted depending on the spatial period of the features (200) so that the transmission grating shifts the phase of the electromagnetic radiation by π or π/2 in order to modify the polarization state.

IPC Classes  ?

• G02B 5/30 - Polarising elements
• G02B 5/18 - Diffracting gratings

Abstract

The present invention concerns novel oxyfluoride derivatives and their preparation, as well as their uses as catalysts in electrochemistry, including the electrodes and electrochemical cells comprising them. These may be useful for hydrogen production.

IPC Classes  ?

• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 11/052 - Electrodes comprising one or more electrocatalytic coatings on a substrate
• C25B 11/065 - Carbon
• C25B 11/077 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the compound being a non-noble metal oxide
• C04B 35/553 - Shaped ceramic products characterised by their composition; Ceramic compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on fluorides
• C04B 35/626 - Preparing or treating the powders individually or as batches
• H01M 4/86 - Inert electrodes with catalytic activity, e.g. for fuel cells
• H01M 4/90 - Selection of catalytic material
• H01M 8/083 - Alkaline fuel cells
• H01M 8/086 - Phosphoric acid fuel cells [PAFC]
• B01J 27/12 - Fluorides
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• H01M 8/1018 - Polymeric electrolyte materials
• H01M 8/10 - Fuel cells with solid electrolytes

Abstract

This method for predicting value(s) of a quantity relative to a target device is implemented by an electronic prediction system and comprises the following steps: - training (100) a prediction probabilistic model, said training (100) including: + receiving (200) measured values of the quantity for N devices, N > 1, + calculating (210) predicted values of the quantity for said N devices with the prediction probabilistic model, + computing (220) a criteria based on the measured values and on the predicted values, + modifying (230) model parameter(s) of the prediction probabilistic model according to the computed criteria, + updating (270) the prediction probabilistic model with the modified model parameter(s), - predicting (110) value(s) of the quantity relative to the target device with the trained prediction probabilistic model; wherein the criteria depends on a predefined distribution quantile.

IPC Classes  ?

• G06N 7/00 - Computing arrangements based on specific mathematical models

Abstract

The invention relates to a method for producing a demixed-layer system, in particular of glass, using a flash thermal treatment by irradiation. The invention also relates to a demixed-layer system obtained in this way.

IPC Classes  ?

• C03C 17/00 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating
• C03C 17/02 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with glass
• C03C 11/00 - Multi-cellular glass

Abstract

The invention relates to an acoustic metamaterial (100, 100'), as well as to a method for manufacturing same. The acoustic metamaterial comprises a plurality of channels (101) or columns (101') each having the same cross-section with a hydraulic radius between 5 and 300 µm, which channels or columns are arranged with a periodic spacing (t,s) between 2 and 600 µm. This results in a highly dense network that can provide optimal acoustic absorption and/or impedance over a wide frequency range. The method for manufacturing same comprises additive manufacturing with a plurality of consecutive material deposition steps to form, in each step, a layer (203) comprising a plurality of periodically repeated cells (204) separated by walls (104). The layers (203) deposited in the consecutive material deposition steps are stacked with their respective cells (204) aligned to form channels (101, 206').

IPC Classes  ?

• G10K 11/162 - Selection of materials
• B33Y 10/00 - Processes of additive manufacturing
• B33Y 80/00 - Products made by additive manufacturing
• B29C 64/00 - Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
• F02C 7/045 - Air intakes for gas-turbine plants or jet-propulsion plants having provisions for noise suppression
• F02K 1/82 - Jet pipe walls, e.g. liners

Abstract

The present invention relates to a compound of formula (I) for use in the treatment of cancer, in particular for treating cancers with CDA under-expressing tumors (I) wherein R1represents a hydrogen atom, a halogen atom, such a bromine atom, a -CHO group or a OR group, R2 represents a -CH=X group, where X represents, an oxygen atom, a -N+O-hi2j1414k m14qq group or n and m are independently equal to 0, 1 or 2 or its pharmaceutically acceptable salt. Herein is further provided a pharmaceutical composition comprising a compound of formula (I) which is new and a process for preparing the same.

IPC Classes  ?

• A61K 31/00 - Medicinal preparations containing organic active ingredients
• A61K 31/11 - Aldehydes
• A61K 31/115 - Formaldehyde
• A61K 31/15 - Oximes (C=N—O—); Hydrazines (N—N); Hydrazones (N—N=)
• A61K 31/18 - Sulfonamides
• A61K 31/22 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
• A61K 31/357 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
• A61K 31/655 - Azo (—N=N—), diazo (=N2), azoxy (N—O—N or N(=O)—N), azido (—N3) or diazoamino (—N=N—N) compounds
• A61K 31/661 - Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion
• A61P 35/00 - Antineoplastic agents
• C07C 1/00 - Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon

Abstract

The present application concerns the use of endoprothesis covalently grafted with a fucoidan for treating aneurysms, in particular cerebral aneurysms, and their process for manufacturing the same. Improved healing of cerebral aneurysms was established in vivo on a rabbit model.

IPC Classes  ?

• A61L 31/02 - Inorganic materials
• A61L 31/10 - Macromolecular materials
• A61L 31/16 - Biologically active materials, e.g. therapeutic substances

Abstract

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or hydrate thereof, for use in the treatment of a viral pulmonary disease or a chronic respiratory distress syndrome (CRDS) resulting from a viral pulmonary disease in a subject, said disease being different from COVID-19, wherein formula (I) is Z-R-A-R'-Y, including plerixafor.

IPC Classes  ?

• A61K 31/395 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
• A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 11/00 - Drugs for disorders of the respiratory system
• A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses
• A61K 31/4353 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
• A61K 31/4427 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
• A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
• A61K 31/404 - Indoles, e.g. pindolol
• A61K 31/573 - Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
• A61P 31/14 - Antivirals for RNA viruses