41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Providing a website featuring nondownloadable publications in the nature of brochures, articles and newsletters in the field of health; Educational services, namely, training in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology and treatments thereof; none of the foregoing services in the field of oral or dental health Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; providing scientific information in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology and treatments thereof via the internet, digital media and data banks; Providing scientific research information concerning clinical study results and clinical study data by means of interactive web sites; none of the foregoing services in the field of oral or dental health
2.
AUTOMATIC INJECTION DEVICES HAVING OVERMOLDED GRIPPING SURFACES
Exemplary embodiments provide automatic injection devices, housing components for automatic injection devices and methods for fabricating the same. An exemplary housing of an automatic injection device may be overmolded with one or more gripping surfaces to facilitate gripping and manipulation of the automatic injection device by a user when performing an injection. In an exemplary embodiment, an overmolded left gripping surface may extend along a left side of the housing and an overmolded right gripping surface may extend along a right side of the housing opposite to the left side.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Providing a website featuring nondownloadable publications in the nature of brochures, articles and newsletters in the field of health; Educational services, namely, training in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology and treatments thereof Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; providing scientific information in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology and treatments thereof via the internet, digital media and data banks; Providing scientific research information concerning clinical study results and clinical study data by means of interactive web sites
The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may have low levels of conductity resulting from the low levels of ionic excipients. Also included in the invention are formulations comprising water and proteins having low osmolality.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
C07K 1/36 - Extraction; Separation; Purification by a combination of two or more processes of different types
C07K 16/06 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies from serum
C07K 1/20 - Partition-, reverse-phase or hydrophobic interaction chromatography
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
A61K 31/519 - Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
6.
FORMULATION OF HUMAN ANTIBODIES FOR TREATING TNF-ALPHA ASSOCIATED DISORDERS
A liquid aqueous pharmaceutical formulation is described which has a high protein concentration, a pH of between about 4 and about 8, and enhanced stability.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 9/19 - Particulate form, e.g. powders lyophilised
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 9/00 - Medicinal preparations characterised by special physical form
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Providing a website featuring nondownloadable publications in the nature of brochures, articles and newsletters in the field of health; Educational services, namely, training in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology, women's health-related diseases, neurological disorders, muscle dystonias, muscle disorders, nerve disorders, headaches, hyperhidrosis, wrinkles, cerebral palsy, spasms, tremors and pain and treatments thereof Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; providing scientific information in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology, women's health-related diseases, neurological disorders, muscle dystonias, muscle disorders, nerve disorders, headaches, hyperhidrosis, wrinkles, cerebral palsy, spasms, tremors and pain and treatments via the internet, digital media and data banks; Providing scientific research information concerning clinical study results and clinical study data by means of interactive web sites
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing consumer product information regarding medical products to patients and healthcare professionals providing medical information, namely, information regarding medical conditions and treatments to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment; providing medical information regarding medical products to patients and healthcare professionals
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing consumer product information regarding medical products to patients and healthcare professionals providing medical information, namely, information regarding medical conditions and treatments to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment; providing medical information regarding medical products to patients and healthcare professionals
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing consumer product information regarding medical products to patients and healthcare professionals providing medical information, namely, information regarding medical conditions and treatments to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment; providing medical information regarding medical products to patients and healthcare professionals
11.
REMOVAL OF NEEDLE SHIELD FROM SYRINGES AND AUTOMATIC INJECTION DEVICES
Elcam Medical Agricultural Cooperative Association Ltd. (Israel)
Inventor
Julian, Joseph F.
Li, Chuan
Anderson, Philip D.
Laurusonis, Linas P.
Raday, Lior
Carmel, Ehud
Marli, Lior
Daily, David
Keenan, Guy
Abstract
Exemplary embodiments provide a needle shield remover that reliably engages with a distal cap of an automatic injection device and with one or more needle shields coupled to a syringe of the device. When a user removes the distal cap, the needle shield remover reliably removes the needle shields (e.g., a soft needle shield and a rigid needle shield) from the syringe, thereby exposing the injection needle for performing an injection. In an exemplary assembly method, a needle shield remover is engaged to a needle shield coupled to a syringe, prior to insertion of the syringe and needle shield remover assembly into a housing of the device. This exemplary assembly method allows visual inspection, outside the housing of the device, to ensure that the needle shield remover is correctly and reliably engaged to the needle shield before the syringe and needle shield remover assembly is inserted into the housing.
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
Multiple-variable dose methods for treating TNFa-related disorders, including Crohn's disease and psoriasis, comprising administering TNFa inhibitors, including TNFa antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/519 - Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
20.
MULTIPLE-VARIABLE DOSE REGIMEN FOR TREATING TNFALPHA-RELATED DISORDERS
Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/519 - Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders
The present disclosure provides novel trispecific molecules that binds to human Survivin, human CD3 and human serum albumin, and methods of making and using the same.
The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may have low levels of conductivity resulting from the low levels of ionic excipients. Also included in the invention are formulations comprising water and proteins having low osmolality.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/00 - Medicinal preparations containing antigens or antibodies
The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may have low levels of conductity resulting from the low levels of ionic excipients. Also included in the invention are formulations comprising water and proteins having low osmolality.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/00 - Medicinal preparations containing antigens or antibodies
Surgical and medical apparatus and instruments, namely, a system for delivery of drugs; medical apparatus and instruments, namely, medical devices for administering pharmaceuticals.
(1) Surgical and medical apparatus and instruments, namely, a system for delivery of drugs; medical apparatus and instruments, namely, medical devices for administering pharmaceuticals
surgical and medical apparatus and instruments, namely, a system for delivery of drugs in the nature of implantable drug delivery ports; medical apparatus and instruments, namely, medical devices in the nature of infusion and injection devices for administering pharmaceuticals
The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing a website featuring medical information; providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Providing a website featuring nondownloadable publications in the nature of brochures, articles and newsletters in the field of health; educational services, namely, training in the field of immunology, auto-immune diseases, rheumatology and treatments thereof providing health information; providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment
41 - Education, entertainment, sporting and cultural services
Goods & Services
Providing a website featuring nondownloadable publications in the nature of brochures, articles and newsletters in the field of health; Educational services, namely, training in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology and treatments thereof
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Providing a website featuring nondownloadable publications in the nature of brochures, articles and newsletters in the field of health; Educational services, namely, training in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology and treatments thereof Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; providing scientific information in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology and treatments thereof via the internet, digital media and data banks; Providing scientific research information concerning clinical study results and clinical study data by means of interactive web sites; Providing scientific information in the field of epidemiology, disease background, real world evidence, pharmaceuticals and clinical trials; providing scientific information in the field of immunology, auto-immune diseases, dermatology, rheumatology, gastroenterology and treatments thereof via the internet, digital media and data banks; provision of scientific information concerning epidemiological study results, real world evidence, clinical study results and clinical study data by means of interactive web sites; providing an interactive web site featuring scientific information on clinical studies and clinical study results Providing health information
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Providing medical information to rheumatologists in the form of reports in the field of conducting ultrasounds on pediatric patients to improve diagnosis and disease management
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Providing medical information to rheumatologists in the form of reports in the field of conducting ultrasounds on pediatric patients to improve diagnosis and disease management.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing medical information to rheumatologists in the form of reports in the field of conducting ultrasounds on pediatric patients to improve diagnosis and disease management
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals concerning viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders; medical consultation, namely, providing advice to healthcare professionals regarding viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders and treatment thereof.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations for the treatment of viral diseases, namely, herpes, hepatitis, acquired immune deficiency syndrome (AIDS); pharmaceutical preparations for the treatment of metabolic diseases and disorders, namely, diabetes, bulimia nervosa, anorexia, obesity, hypothyroidism, hypoglycemia, gout, osteoarthritis, muscular dystrophy and anemia; pharmaceutical preparations for the treatment of diseases, disorders and infections of the endocrine system, namely, growth and thyroid disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue disease, bone diseases, spinal diseases, back pain, fractures, sprains and cartilage injuries; pharmaceutical preparations for the treatment of cardiovascular and cardiopulmonary diseases and disorders; pharmaceutical preparations for the treatment of genitourinary diseases, namely, urological diseases, infertility, sexually transmitted diseases, incontinence, inflammatory pelvic diseases and sexual dysfunction; pharmaceutical preparations for the treatment of oncological diseases and disorders; pharmaceutical preparations and substances for the treatment of ophthalmic, respiratory and gastrointestinal diseases and disorders; pharmaceutical preparations for the treatment of neurological diseases and disorders, namely, Parkinson's, Alzheimer's, Huntington's disease, cerebral palsy, brain injury, spinal cord injury and seizure disorders; pharmaceutical hormonal preparations, namely, corticosteroids, hormone replacement therapy preparations, oral contraceptives, thyroid hormone preparations; pharmaceutical preparations for use in dermatology, namely, dermatitis, skin pigmentation diseases, acne, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections; pharmaceutical preparations for the treatment of psychiatric diseases, namely, mood disorders, anxiety disorders, cognitive disorders and schizophrenia; pharmaceutical preparations for the treatment of immunologic diseases, namely, autoimmune diseases and immunologic deficiency syndromes; pharmaceutical preparations for the treatment and prevention of migraines, headaches and pain.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing medical information, namely, consumer product information regarding medical products to patients and healthcare professionals providing medical information, namely, information regarding medical conditions, treatments to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing consumer product information regarding medical products to patients and healthcare professionals Providing medical information, namely, information regarding medical conditions, treatments to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations for the treatment of viral diseases, namely herpes, hepatitis, acquired immune deficiency syndrome (AIDS); pharmaceutical preparations for the treatment of metabolic diseases and disorders, namely diabetes, bulimia nervosa, anorexia, obesity, hypothyroidism, hypoglycemia, gout, osteoarthritis, muscular dystrophy and anemia; pharmaceutical preparations for the treatment of diseases, disorders and infections of the endocrine system, namely growth and thyroid disorders; pharmaceutical preparations for the treatment of the musculoskeletal system, namely, connective tissue disease, bone diseases, spinal diseases, back pain, fractures, sprains and cartilage injuries; pharmaceutical preparations for the treatment of cardiovascular and cardiopulmonary diseases and disorders; pharmaceutical preparations for the treatment of genitourinary diseases, namely, urological diseases, infertility, sexually transmitted diseases, incontinence, inflammatory pelvic diseases and sexual dysfunction; pharmaceutical preparations for the treatment of oncological diseases and disorders; pharmaceutical preparations and substances for the treatment of ophthalmic, respiratory and gastrointestinal diseases and disorders; pharmaceutical preparations for the treatment of neurological diseases and disorders, namely, Parkinson's, Alzheimer's, Huntington's disease, cerebral palsy, brain injury, spinal cord injury and seizure disorders; pharmaceutical hormonal preparations, namely, corticosteroids, hormone replacement therapy preparations, oral contraceptives, thyroid hormone preparations; pharmaceutical preparations for use in dermatology, namely, dermatitis, skin pigmentation diseases, acne, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections; pharmaceutical preparations for the treatment of psychiatric diseases, namely, mood disorders, anxiety disorders, cognitive disorders and schizophrenia; pharmaceutical preparations for the treatment of immunologic diseases, namely, autoimmune diseases and immunologic deficiency syndromes; pharmaceutical preparations for the treatment and prevention of migraines, headaches and pain.
56.
Automatic injection devices having overmolded gripping surfaces
Exemplary embodiments provide automatic injection devices, housing components for automatic injection devices and methods for fabricating the same. An exemplary housing of an automatic injection device may be overmolded with one or more gripping surfaces to facilitate gripping and manipulation of the automatic injection device by a user when performing an injection. In an exemplary embodiment, an overmolded left gripping surface may extend along a left side of the housing and an overmolded right gripping surface may extend along a right side of the housing opposite to the left side.
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals concerning viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders; medical consultation, namely, providing advice to healthcare professionals regarding viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders and treatment thereof
The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
A61K 31/519 - Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
C07K 16/06 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies from serum
C07K 1/36 - Extraction; Separation; Purification by a combination of two or more processes of different types
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Provision of medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals and promoting awareness of inflammatory bowel disease among consumers, health care professionals and government agencies in Class 44.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Providing medical information to patients and healthcare professionals, namely, information regarding medical conditions and treatments; Medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances for the treatment of viral diseases, namely herpes, hepatitis, Acquired Immune Deficiency Syndrome (AIDS); pharmaceutical preparations and substances for the treatment of metabolic diseases and disorders, namely diabetes, bulimia nervosa, anorexia, obesity, hypothyroidism, hypoglycemia, gout, osteoarthritis, muscular dystrophy and anemia; pharmaceutical preparations and substances for the treatment of diseases, disorders and infections of the endocrine system, namely growth and thyroid disorders; pharmaceutical preparations and substances for the treatment of the musculoskeletal system, namely, connective tissue disease, bone diseases, spinal diseases, back pain, fractures, sprains and cartilage injuries; pharmaceutical preparations and substances for the treatment of cardiovascular and cardiopulmonary diseases and disorders; pharmaceutical preparations and substances for the treatment of genitourinary diseases, namely, urological diseases, infertility, sexually transmitted diseases, incontinence, inflammatory pelvic diseases and sexual dysfunction; pharmaceutical preparations and substances for the treatment of oncological diseases and disorders; pharmaceutical preparations and substances for the treatment of ophthalmic, respiratory and gastrointestinal diseases and disorders; pharmaceutical preparations and substances for the treatment of neurological diseases and disorders, namely, Alzheimer's, Huntington's Disease, cerebral palsy, brain injury, spinal cord injury and seizure disorders; pharmaceutical hormonal preparations, namely, corticosteroids, hormone replacement therapy preparations, oral contraceptives, thyroid hormone preparations; pharmaceutical preparations for use in dermatology, namely, dermatitis, skin pigmentation diseases, acne, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections; pharmaceutical preparations and substances for the treatment of psychiatric diseases, namely, mood disorders, anxiety disorders, cognitive disorders and schizophrenia; pharmaceutical preparations and substances for the treatment of immunologic diseases, namely, autoimmune diseases and immunologic deficiency syndromes
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances for the treatment of viral diseases, namely herpes, hepatitis, Acquired Immune Deficiency Syndrome (AIDS); pharmaceutical preparations and substances for the treatment of metabolic diseases and disorders, namely diabetes, bulimia nervosa, anorexia, obesity, hypothyroidism, hypoglycemia, gout, osteoarthritis, muscular dystrophy and anemia; pharmaceutical preparations and substances for the treatment of diseases, disorders and infections of the endocrine system, namely growth and thyroid disorders; pharmaceutical preparations and substances for the treatment of the musculoskeletal system, namely, connective tissue disease, bone diseases, spinal diseases, back pain, fractures, sprains and cartilage injuries; pharmaceutical preparations and substances for the treatment of cardiovascular and cardiopulmonary diseases and disorders; pharmaceutical preparations and substances for the treatment of genitourinary diseases, namely, urological diseases, infertility, sexually transmitted diseases, incontinence, inflammatory pelvic diseases and sexual dysfunction; pharmaceutical preparations and substances for the treatment of oncological diseases and disorders; pharmaceutical preparations and substances for the treatment of ophthalmic, respiratory and gastrointestinal diseases and disorders; pharmaceutical preparations and substances for the treatment of neurological diseases and disorders, namely, Alzheimer's, Huntington's Disease, cerebral palsy, brain injury, spinal cord injury and seizure disorders; pharmaceutical hormonal preparations, namely, corticosteroids, hormone replacement therapy preparations, oral contraceptives, thyroid hormone preparations; pharmaceutical preparations for use in dermatology, namely, dermatitis, skin pigmentation diseases, acne, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections; pharmaceutical preparations and substances for the treatment of psychiatric diseases, namely, mood disorders, anxiety disorders, cognitive disorders and schizophrenia; pharmaceutical preparations and substances for the treatment of immunologic diseases, namely, autoimmune diseases and immunologic deficiency syndromes
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders; all of the aforementioned provided by prescription.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Pharmaceutical preparations and substances for the treatment of viral diseases, namely herpes, hepatitis, Acquired Immune Deficiency Syndrome (AIDS); pharmaceutical preparations and substances for the treatment of metabolic diseases and disorders, namely diabetes, bulimia nervosa, anorexia, obesity, hypothyroidism, hypoglycemia, gout, osteoarthritis, muscular dystrophy and anemia; pharmaceutical preparations and substances for the treatment of diseases, disorders and infections of the endocrine system, namely growth and thyroid disorders; pharmaceutical preparations and substances for the treatment of the musculoskeletal system, namely, connective tissue disease, bone diseases, spinal diseases, back pain, fractures, sprains and cartilage injuries; pharmaceutical preparations and substances for the treatment of cardiovascular and cardiopulmonary diseases and disorders; pharmaceutical preparations and substances for the treatment of genitourinary diseases, namely, urological diseases, infertility, sexually transmitted diseases, incontinence, inflammatory pelvic diseases and sexual dysfunction; pharmaceutical preparations and substances for the treatment of oncological diseases and disorders; pharmaceutical preparations and substances for the treatment of ophthalmic, respiratory and gastrointestinal diseases and disorders; pharmaceutical preparations and substances for the treatment of neurological diseases and disorders, namely, Alzheimer's, Huntington's Disease, cerebral palsy, brain injury, spinal cord injury and seizure disorders; pharmaceutical hormonal preparations, namely, corticosteroids, hormone replacement therapy preparations, oral contraceptives, thyroid hormone preparations; pharmaceutical preparations for use in dermatology, namely, dermatitis, skin pigmentation diseases, acne, bacterial skin infections, fungal skin infections, viral skin infections and parasitic skin infections; pharmaceutical preparations and substances for the treatment of psychiatric diseases, namely, mood disorders, anxiety disorders, cognitive disorders and schizophrenia; pharmaceutical preparations and substances for the treatment of immunologic diseases, namely, autoimmune diseases and immunologic deficiency syndromes
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Research services in the field of auto-immune disorders; hosting an interactive website for patients that provides healthcare professional support and healthcare information
(2) Medical services namely medical counseling and diagnostic services in the field of auto-immune disorders; health and well-being services, namely personal and emotional support services for families of patients with health disorders and providing medical consultation regarding same; health assessment services namely provision of information to healthcare professionals and patients on self-health assessment; a patient assistance and support program namely, providing support in the delivery and administration of medication; the operation of a patient telephone help line to provide healthcare professional support, medical advice; health management services namely holistic health services to support patients' physical, mental and emotional general health and well-being, patient support programs to assist with patients' general health and well-being, health coaching services to support patients' general health and well-being and health mentoring services to support patients' general health and well-being; nursing and personal caregiver services; preventative health care services and programs, namely nutrition, lifestyle, and medication management counseling; chronic disease management services and programs, namely nutrition, lifestyle, and medication management counseling; hospital substitute services and programs, namely home health care services; occupational health and safety services, namely therapeutic and rehabilitation services; medical counseling services in the field of auto-immune disorders; pharmacy advice and pharmacy dispensary services; drug administration services, alternative medical services and complementary medical services, namely homeopathy services; consultancy and advisory services in relation to auto-immune disorders; providing information in relation to auto-immune disorders
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals; medical consultation, namely, providing advice to healthcare professionals regarding medical conditions and treatment
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
providing a website featuring medical information; providing medical information, namely, information regarding medical conditions, treatments and products to patients and healthcare professionals
05 - Pharmaceutical, veterinary and sanitary products
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Pharmaceutical preparations for the treatment of viral diseases, namely, herpes, hepatitis, Acquired Immune Deficiency Syndrome (AIDS), metabolic diseases, namely, diabetes, hypoglycaemia, gout, osteoarthritis, muscular dystrophy, anemia, bulimia nervosa, anorexia, obesity and hypothyroidism, endocrine diseases, namely, growth and thyroid disorders, musculoskeletal system diseases and disorders, namely, connective tissue diseases, bone diseases, spinal diseases, back pain, fractures, sprains, cartilage injuries, cardiovascular, cardiopulmonary, genitourinary diseases, namely, urological diseases, infertility, sexually transmitted diseases, inflammatory pelvic diseases, reproductive diseases, namely, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological diseases and disorders, namely, Alzheimer's, Huntington's Disease, cerebral palsy, brain injury, spinal cord injury, seizure disorders, gastrointestinal, hormonal preparations, namely, corticosteroids, hormone replacement therapy preparations, oral contraceptives, thyroid hormone preparations, pharmaceutical preparations for use in dermatology, namely, dermatitis, psoriasis, skin pigmentation diseases, sexually transmitted diseases, psychiatric and other brain diseases and disorders, namely, anxiety, mood disorders, schizophrenia, cognitive and bipolar disorders, epilepsy, Alzheimer's, cerebral palsy, Parkinson's disease, multiple sclerosis, sleep, central nervous system and immune system related diseases and disorders, namely, central nervous system infections, brain diseases, central nervous system movement disorders, ocular motility disorders, spinal cord diseases, autoimmune diseases, and immunologic deficiency syndromes; pharmaceutical preparations for the treatment of infectious diseases, namely, blood disorders, pain, inflammation diseases, namely, inflammatory bowel diseases, inflammatory connective tissue diseases, sepsis, alopecia, obesity and cognitive disorders (1) Manufacturing services in the field of low ionic formulation of proteins; chemical treatment processing of pharmaceutical agents in the field of low ionic formulation of proteins
(2) Medical research and product development in the field of low ionic formulation of proteins
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders
The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 9/00 - Medicinal preparations characterised by special physical form
81.
Removal of needle shield from syringes and automatic injection devices
Elcam Medical Agricultural Cooperative Association Ltd (Israel)
Inventor
Julian, Joseph F.
Li, Chuan
Anderson, Philip D.
Laurusonis, Linas P.
Raday, Lior
Carmel, Ehud
Marli, Lior
Daily, David
Keenan, Guy
Abstract
Exemplary embodiments provide a needle shield remover that reliably engages with a distal cap of an automatic injection device and with one or more needle shields coupled to a syringe of the device. When a user removes the distal cap, the needle shield remover reliably removes the needle shields (e.g., a soft needle shield and a rigid needle shield) from the syringe, thereby exposing the injection needle for performing an injection. In an exemplary assembly method, a needle shield remover is engaged to a needle shield coupled to a syringe, prior to insertion of the syringe and needle shield remover assembly into a housing of the device. This exemplary assembly method allows visual inspection, outside the housing of the device, to ensure that the needle shield remover is correctly and reliably engaged to the needle shield before the syringe and needle shield remover assembly is inserted into the housing.
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 39/00 - Medicinal preparations containing antigens or antibodies
84.
Automatic injection devices having overmolded gripping surfaces
Exemplary embodiments provide automatic injection devices, housing components for automatic injection devices and methods for fabricating the same. An exemplary housing of an automatic injection device may be overmolded with one or more gripping surfaces to facilitate gripping and manipulation of the automatic injection device by a user when performing an injection. In an exemplary embodiment, an overmolded left gripping surface may extend along a left side of the housing and an overmolded right gripping surface may extend along a right side of the housing opposite to the left side.
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
B23P 17/04 - Metal-working operations, not covered by a single other subclass or another group in this subclass characterised by the nature of the material involved or the kind of product independently of its shape
B05D 1/36 - Successively applying liquids or other fluent materials, e.g. without intermediate treatment
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
The invention provides methods and compositions for the treatment of juvenile idiopathic arthritis (JIA) where a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat JIA. In particular, the invention is directed to methods and compositions relating to a fixed dosing regimen for treating JIA with a TNFα inhibitor.
A61K 39/00 - Medicinal preparations containing antigens or antibodies
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A method for treating a disorder using an automatic injection device is disclosed. The device includes a syringe movably disposed in a housing and including a barrel portion, a needle and a bung for sealing the barrel portion. The device includes a syringe actuation component for moving the syringe towards a first open end of the housing such that the needle projects from the first end, and for subsequently applying pressure to the bung. The syringe actuation component includes a pressurizer, a rod comprising a compressible portion projecting therefrom, and a flange between a second end of the rod and the compressible portion. The device also includes a biasing mechanism for biasing the syringe actuation component towards the first open end of the housing, the biasing mechanism disposed about the second end of the rod between the flange and a second end of the housing.
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A61M 5/46 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for controlling depth of insertion
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
87.
Wearable automatic injection device for controlled delivery of therapeutic agents
Exemplary embodiments provide wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates, for example, in a single bolus. Exemplary embodiments provide methods for assembling wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates. Exemplary embodiments provide methods for using wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates.
A61M 5/14 - Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A61M 5/48 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for varying, regulating, indicating or limiting injection pressure
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
The invention provides methods and compositions for the treatment of juvenile idiopathic arthritis (JIA) where a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat JIA. In particular, the invention is directed to methods and compositions relating to a fixed dosing regimen for treating JIA with a TNFα inhibitor.
A61K 39/00 - Medicinal preparations containing antigens or antibodies
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
45 - Legal and security services; personal services for individuals.
Goods & Services
(1) Medical services, namely medical counseling, diagnostic and research services in the field of auto-immune disorders; health and well-being services, namely providing support, medical advice, and educational information and training to healthcare professionals and patients in connection with auto-immune disorders; health assessment services, namely provision of information to healthcare professionals and patients on self-health assessment; a patient assistance and support program namely, providing support in the delivery and administration of medication; the operation of a patient telephone help line to provide healthcare professional support, medical advice, educational information and training in the field of healthcare to patients on the delivery and administration of medication; the operation of an interactive website for patients that provides healthcare professional support, information and training on delivery and administration of medication; health management services, namely holistic health services to support patients' physical, mental and emotional general health and well-being, patient support programs, health coaching services to support patients' general health and well-being and health mentoring services to support patients' general health and well-being; nursing and personal caregiver services; preventative health care services and programs, namely nutrition, lifestyle, and medication management counseling; chronic disease management services and programs, namely nutrition, lifestyle, and medication management counseling; hospital substitute services and programs, namely home health care services; occupational health and safety services and programs, namely therapeutic and rehabilitation services; pharmacy advice and pharmacy dispensary services; drug administration services, alternative medical services and complementary medical services, namely homeopathy services; consultancy and advisory services in relation to auto-immune disorders; providing information in relation to auto-immune disorders
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
45 - Legal and security services; personal services for individuals.
Goods & Services
(1) Medical services, namely medical counseling, diagnostic and research services in the field of auto-immune disorders; health and well-being services, namely providing support, medical advice, and educational information and training to healthcare professionals and patients in connection with auto-immune disorders; health assessment services, namely provision of information to healthcare professionals and patients on self-health assessment; a patient assistance and support program namely, providing support in the delivery and administration of medication; the operation of a patient telephone help line to provide healthcare professional support, medical advice, educational information and training in the field of healthcare to patients on the delivery and administration of medication; the operation of an interactive website for patients that provides healthcare professional support, information and training on delivery and administration of medication; health management services, namely holistic health services to support patients' physical, mental and emotional general health and well-being, patient support programs, health coaching services to support patients' general health and well-being and health mentoring services to support patients' general health and well-being; nursing and personal caregiver services; preventative health care services and programs, namely nutrition, lifestyle, and medication management counseling; chronic disease management services and programs, namely nutrition, lifestyle, and medication management counseling; hospital substitute services and programs, namely home health care services; occupational health and safety services and programs, namely therapeutic and rehabilitation services; pharmacy advice and pharmacy dispensary services; drug administration services, alternative medical services and complementary medical services, namely homeopathy services; consultancy and advisory services in relation to auto-immune disorders; providing information in relation to auto-immune disorders
The invention provides a method for producing a host cell protein—(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Providing medical information services in the field of health care; providing information concerning medicines; providing medical information for medical, scientific research, and regulatory purposes; informational services in the field of health care; providing medical information in the field of health care via telephone, facsimile, mail, email, private network, printed materials, and the internet.
A computer system for processing a prescription for a prescription product prescribed by a healthcare provider (HCP) to a patient includes a memory device and a processor. The processor is programmed to receive patient data and insurance data from an HCP computing device, the patient data including a completed prescription form for the prescription product, and the insurance data identifying an insurance provider, wherein the prescription product is an antiviral product, store the patient data and the insurance data, determine a current electronic prior authorization request form, transmit the determined current electronic prior authorization request form to the HCP computing device, and prompt an HCP user to complete the determined current electronic prior authorization request form by enabling the HCP user to automatically populate at least one data field included within the determined current electronic prior authorization request form.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
An injection device comprises a syringe extendible against a spring bias from a retracted position in a housing to a projecting injecting position. A spring biased plunger has collapsible elbows which, when the plunger is released, initially engage the end of the syringe to drive it to the projecting position, whereupon arresting of the syringe movement causes the elbows to collapse inside the syringe to allow the plunger to engage and drive the bung.
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
96.
Multiple-variable dose regimen for treating idiopathic inflammatory bowel disease
Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/00 - Medicinal preparations containing antigens or antibodies
97.
Methods of treating moderate to severe hidradenitis suppurativa with anti-TNFalpha antibody
The invention provides methods, uses and compositions for the treatment of hidradenitis suppurativa. The invention describes methods and uses for treating hidradenitis suppurativa, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat hidradenitis suppurativa in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treating hidradenitis suppurativa in a subject.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/00 - Medicinal preparations containing antigens or antibodies
The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum