Shimadzu Corporation

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G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode 614
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1.

GAS CHROMATOGRAPH ASSISTANCE DEVICE AND GAS CHROMATOGRAPH ASSISTANCE METHOD

      
Application Number 18378558
Status Pending
Filing Date 2023-10-10
First Publication Date 2024-04-18
Owner Shimadzu Corporation (Japan)
Inventor Fukushima, Daiki

Abstract

A GC assistance device includes a saving amount evaluator, a consumption amount evaluator and an outputter, and is used together with a gas chromatograph. The saving amount evaluator evaluates a saving amount of a resource caused by stopping of the gas chromatograph. The consumption amount evaluator evaluates a consumption amount of the resource caused by recovery of the gas chromatograph from a stop state. The outputter presents an evaluation value in regard to the saving amount and the consumption amount to a user. Alternatively, the outputter controls an operation state of the gas chromatograph based on the evaluation value.

IPC Classes  ?

  • G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups

2.

FLOW RATE SWITCHING MECHANISM AND MASS SPECTROMETER

      
Application Number 18485311
Status Pending
Filing Date 2023-10-12
First Publication Date 2024-04-18
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Shiba, Shunki
  • Matsushita, Tomoyoshi

Abstract

A flow rate switching mechanism including: a first section including: a first housing with a passage internally bored through, the passage having a narrowed portion at a distance from one end of the passage, and the narrowed portion having a smaller cross-sectional area than the cross-sectional area of the passage at the one end; a capillary having an internal passage having a smaller cross-sectional area than the cross-sectional area of the narrowed portion; and a hermetic support member supporting the capillary and to provide a seal; a second section having a second housing identical in shape to the first housing, without having the capillary and the hermetic support member; and a three-way valve being alternatively switchable between a first state in which the outlet end is connected to the first inlet end and a second state in which the outlet end is connected to the second inlet end.

IPC Classes  ?

  • H01J 49/24 - Vacuum systems, e.g. maintaining desired pressures
  • F25B 41/42 - Arrangements for diverging or converging flows, e.g. branch lines or junctions
  • H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components

3.

TREATMENT DEVICE

      
Application Number JP2022038157
Publication Number 2024/079837
Status In Force
Filing Date 2022-10-13
Publication Date 2024-04-18
Owner SHIMADZU CORPORATION (Japan)
Inventor Ikezawa, Yoshio

Abstract

A treatment device (1) is provided with: a vessel (50) for containing a sample; pipes (11-13) for introducing, into the vessel, a treatment liquid for decomposing an impurity contained in the sample; a port (64) that discharges, from the vessel containing the sample, a liquid contained in the sample as waste liquid; a pump (33) connected to the port; and a control device (500) for controlling the pump. The control device controls the pump so as to enable a predetermined amount or more of the waste liquid to be discharged from the port.

IPC Classes  ?

  • G01N 1/04 - Devices for withdrawing samples in the solid state, e.g. by cutting
  • B03D 1/14 - Flotation machines

4.

DIAGNOSIS SUPPORT METHOD, DIAGNOSIS SUPPORT PROGRAM, AND DIAGNOSIS SUPPORT SYSTEM

      
Application Number JP2023026093
Publication Number 2024/079957
Status In Force
Filing Date 2023-07-14
Publication Date 2024-04-18
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Hirose, Ryuta
  • Hasegawa, Yukinori
  • Nakaya, Tomohiro
  • Uno, Haruo
  • Oyama, Shintaro
  • Nakagawa, Yasunobu
  • Yagi, Tetsuya
  • Iguchi, Mitsutaka

Abstract

Provided is a diagnosis support system that acquires one or more items of patient information associated with a patient (steps S30, S40), and inputs the one or more items into an estimation model and acquires, from a plurality of diseases, a candidate for a disease that the patient may have (step S50). The diagnosis support system then acquires additional required information to be additionally acquired from the patient on the basis of the candidate for the disease (step S70). The diagnosis support system then presents the additional required information (step S90).

IPC Classes  ?

  • G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

5.

QUALITY CONTROL STANDARD SOLUTION USED IN PEPTIDE ASSAY, AND QUALITY CONTROL OF PEPTIDE ASSAY

      
Application Number 18278094
Status Pending
Filing Date 2022-02-02
First Publication Date 2024-04-18
Owner SHIMADZU CORPORATION (Japan)
Inventor Yoda, Ritsuko

Abstract

A quality control standard for peptide (including protein) measurement, and a quality control for peptide (including proteins) measurement are provided. A QC standard sample for measurement of a target peptide, the QC standard sample comprising: a blood sample comprising a peptide, and a peptide labeled with a stable isotope that is spiked into said blood sample. The target peptide to be measured includes, for example, at least one selected from the group consisting of Aβ1-42 (SEQ ID NO.: 9), Aβ1-38 (SEQ ID NO.: 11), Aβ1-40 (SEQ ID NO.: 7), and APP669-711 (SEQ ID NO.: 10). The peptide labeled with a stable isotope that is spiked into the blood sample includes, for example, at least one selected from the group consisting of SIL-Aβ1-42, SIL-Aβ1-38, SIL-Aβ1-40, and SIL-APP669-711.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • G01N 30/02 - Column chromatography
  • G01N 33/58 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

6.

METHOD FOR FILLING HEAT TRANSPORT DEVICE WITH REFRIGERANT AND REFRIGERANT FILLING CONTROL DEVICE FOR HEAT TRANSPORT DEVICE

      
Application Number JP2023036301
Publication Number 2024/080213
Status In Force
Filing Date 2023-10-05
Publication Date 2024-04-18
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Sekimoto, Shunsuke
  • Horiguchi, Yukio
  • Matsuda, Shotaro
  • Nishiura, Yoshiaki

Abstract

This method for filling a heat transport device (110) with a refrigerant comprises: a pre-filling step (step 902) for filling a refrigerant flow path (10) of a heat transport device (110) with an inactive gas such that the pressure inside the refrigerant flow path (10) of the heat transport device (110) reaches a prescribed pressure; and a main filling step (step 904) for filling the refrigerant flow path (10) of the heat transport device (110) with a refrigerant to a prescribed quantity necessary for operating the heat transport device (110), after the pre-filling step (step 902).

IPC Classes  ?

  • F25B 45/00 - Arrangements for charging or discharging refrigerant
  • F25B 1/00 - Compression machines, plants or systems with non-reversible cycle
  • F28D 15/02 - Heat-exchange apparatus with the intermediate heat-transfer medium in closed tubes passing into or through the conduit walls in which the medium condenses and evaporates, e.g. heat-pipes

7.

FLOW PATH STATE OUTPUT DEVICE

      
Application Number JP2023036580
Publication Number 2024/080246
Status In Force
Filing Date 2023-10-06
Publication Date 2024-04-18
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Shimizu, Satoshi
  • Morita, Daisuke

Abstract

A computer according to an embodiment of this flow path state output device is connected to a liquid chromatograph and obtains the result of analysis processing performed by the liquid chromatograph. The computer comprises a feature amount acquisition unit and a state output unit. The feature amount acquisition unit measures a sample containing a known component by means of an analysis device, and obtains a feature amount from the measurement result. The state output unit outputs the flow path state of the liquid chromatograph to a display on the basis of the feature amount.

IPC Classes  ?

  • G01N 30/86 - Signal analysis
  • G01N 30/26 - Conditioning of the fluid carrier; Flow patterns
  • G01N 30/32 - Control of physical parameters of the fluid carrier of pressure or speed

8.

PROCESSING DEVICE, PROCESSING METHOD, AND CONTROL PROGRAM

      
Application Number JP2022038156
Publication Number 2024/079836
Status In Force
Filing Date 2022-10-13
Publication Date 2024-04-18
Owner SHIMADZU CORPORATION (Japan)
Inventor Ikezawa, Yoshio

Abstract

A processing device (1) comprises: a container (50) that accommodates a specimen; a control device (500) that extracts a target substance from the specimen accommodated in the container; and an input device (505) that receives input from a user. The control device performs a refresh process in which a first processing liquid for processing a contaminant included in the specimen is introduced into the container in which the specimen is accommodated, and after the first processing liquid has been introduced, on the basis of an input to the input device, a second processing liquid for re-processing the contaminant included in the specimen is introduced into the container.

IPC Classes  ?

  • G01N 1/04 - Devices for withdrawing samples in the solid state, e.g. by cutting
  • B03D 1/14 - Flotation machines

9.

RECOVERY IMPLEMENT AND RECOVERY SYSTEM

      
Application Number JP2022038155
Publication Number 2024/079835
Status In Force
Filing Date 2022-10-13
Publication Date 2024-04-18
Owner SHIMADZU CORPORATION (Japan)
Inventor Ikezawa, Yoshio

Abstract

This recovery implement (100) recovers subject material contained in a discharged liquid that is discharged from each of a plurality of treatment devices (1A, 1B, 1C) for treating samples. The recovery implement comprises: a plurality of filtration units (110A, 110B, 110C) that are provided corresponding to the plurality of treatment devices, the filtration units filtering the discharged liquid that is discharged from the corresponding treatment devices and extracting the subject material contained in the discharged liquid; a holder (101) that integrally accommodates the plurality of filtration units; and a discharge unit (102) that discharges a waste liquid that has passed through each of the plurality of filtration units. The holder can be detached from the discharge unit together with the plurality of filtration units in which the subject material resides.

IPC Classes  ?

  • B01D 29/90 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups ;   Filtering elements therefor having feed or discharge devices for feeding
  • B01D 29/01 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups ;   Filtering elements therefor with flat filtering elements
  • G01N 1/04 - Devices for withdrawing samples in the solid state, e.g. by cutting

10.

ELEM-SPOT

      
Application Number 019012917
Status Pending
Filing Date 2024-04-12
Owner Shimadzu Corporation (Japan)
NICE Classes  ? 09 - Scientific and electric apparatus and instruments

Goods & Services

Gas Chromatograph; Mass Spectrometer with an element-selective combustion unit included for selectively analyzing nitrogen-containing compounds or oxygenated compounds in complex hydrocarbon compounds with high sensitivity.

11.

AIR MEASUREMENT METHOD USING GAS CHROMATOGRAPH AND GAS CHROMATOGRAPH ANALYSIS SYSTEM

      
Application Number 18276858
Status Pending
Filing Date 2021-09-22
First Publication Date 2024-04-11
Owner SHIMADZU CORPORATION (Japan)
Inventor Uchiyama, Shinji

Abstract

An air measurement method of performing measurement by injecting air into a gas chromatograph includes a liquid suction step of sucking a liquid that does not interfere with detection of a predetermined component in air by a gas chromatograph into a syringe to fill the syringe with the liquid, an air suction step of sucking a predetermined amount of air into the syringe after the liquid suction step, an injection step of injecting the predetermined amount of air sucked into the syringe into the gas chromatograph after the air suction step, and a recording step of acquiring a detection signal for the air injected into the gas chromatograph in the injection step and recording an acquired detection signal in association with the air injection amount into the gas chromatograph.

IPC Classes  ?

  • G01N 30/18 - Injection using a septum or microsyringe

12.

TIME-OF-FLIGHT MASS SPECTROMETRY DEVICE AND ANALYSIS METHOD

      
Application Number 17768747
Status Pending
Filing Date 2020-08-17
First Publication Date 2024-04-11
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Kishida, Takuro
  • Aoki, Yasushi
  • Kawai, Toshitaka

Abstract

A time-of-flight mass spectrometry device includes an electrode to which a DC high voltage is applied in order to form an ion flight space and a high voltage power supply device that applies the high voltage to the electrode. The high voltage power supply device includes a high voltage generating circuit that generates the high voltage, and a voltage control circuit that is selectively set to a convergence responsiveness priority mode in which the high voltage generating circuit is controlled such that the high voltage has first convergence responsiveness and first stability or a stability priority mode in which the high voltage generating circuit is controlled such that the high voltage has second convergence responsiveness that is lower than the first convergence responsiveness and second stability that is higher than the first stability.

IPC Classes  ?

  • H01J 49/40 - Time-of-flight spectrometers
  • H01J 49/02 - Particle spectrometers or separator tubes - Details

13.

ELEM-SPOT

      
Serial Number 98495847
Status Pending
Filing Date 2024-04-11
Owner SHIMADZU CORPORATION (Japan)
NICE Classes  ? 09 - Scientific and electric apparatus and instruments

Goods & Services

Gas chromatograph mass spectrometer with an element-selective combustion unit included for selectively analyzing nitrogen-containing compounds or oxygenated compounds in complex hydrocarbon compounds with high sensitivity

14.

Estimation Device, Learning Device, Optimization Device, Estimation Method, Learning Method, and Optimization Method

      
Application Number 18275969
Status Pending
Filing Date 2022-01-31
First Publication Date 2024-04-11
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Suzuki, Takashi
  • Yamamoto, Shuhei
  • Toyoda, Kenichi
  • Kuroda, Hirotaka

Abstract

An estimation device (200) generates quality prediction data (540) indicating a quality of a drug substance of a biopharmaceutical manufactured by culturing cells, by inputting, into a prediction model (420), measurement data (510) including a measurement result obtained by measuring a substance in a culturing vessel at least one timing after a predetermined time period has passed since the cells have been seeded in a medium. The prediction model (420) is generated by executing a learning process using training data (530) that includes measurement data including a measurement result obtained by measuring a substance in a culturing vessel at a plurality of timings after seeding of the cells in the medium, and quality data obtained by analyzing a drug substance of the biopharmaceutical manufactured from the cells.

IPC Classes  ?

  • G16C 20/30 - Prediction of properties of chemical compounds, compositions or mixtures
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
  • G16C 20/70 - Machine learning, data mining or chemometrics
  • G16C 20/80 - Data visualisation

15.

BIOCHEMICAL ANALYSIS APPARATUS AND BIOCHEMICAL ANALYSIS METHOD

      
Application Number 18388745
Status Pending
Filing Date 2023-11-10
First Publication Date 2024-04-11
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Onoki, Takanori
  • Sugiyama, Kiyohiro

Abstract

A biochemical analysis apparatus includes a piercer for piercing a cover member, a nozzle that passes through the piercer which has pierced the cover member and suctions a specimen, a liquid surface sensor that detects contact of the nozzle with the specimen, and a controller that drives the nozzle and the piercer, in which the controller provides an error notification upon detection of contact of the nozzle with the accommodation object inside the piercer, and upon detection of a collision of the nozzle with the cover member.

IPC Classes  ?

  • G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor
  • G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

16.

METHOD FOR ANALYZING DATA ACQUIRED BY MALDI MASS SPECTROMETRY, DATA-PROCESSING DEVICE, MASS SPECTROMETER, AND DATA-ANALYZING PROGRAM

      
Application Number 17960609
Status Pending
Filing Date 2022-10-05
First Publication Date 2024-04-11
Owner SHIMADZU CORPORATION (Japan)
Inventor Teramoto, Kanae

Abstract

A method for analyzing MALDI mass spectrometry data includes: calculating m/z values respectively corresponding to peaks in amass spectrum, from data corresponding to the mass spectrum acquired by MALDI mass spectrometry performed on a sample; and performing at least one of calculations (a) and (b), based on the m/z values and information on kinds of ions possibly generated from the sample in the mass spectrometry, where calculation (a) includes assuming that ions respectively corresponding to the peaks are first ions singly charged, and calculating m/z of second ions respectively corresponding to the first ions and being multiply charged, and calculation (b) includes assuming that ions respectively corresponding to the peaks are first ions that are multiply charged ions, and calculating m/z of second ions respectively corresponding to the first ions and being singly charged.

IPC Classes  ?

  • H01J 49/16 - Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
  • H01J 49/00 - Particle spectrometers or separator tubes
  • H01J 49/40 - Time-of-flight spectrometers

17.

METHOD AND DEVICE FOR SUGGESTING POSITIONING OF ELECTROMAGNETIC SENSORS, AND CURRENT SOURCE LOCATION ESTIMATION METHOD

      
Application Number JP2023035835
Publication Number 2024/075669
Status In Force
Filing Date 2023-10-02
Publication Date 2024-04-11
Owner
  • SHIMADZU CORPORATION (Japan)
  • RIKEN (Japan)
Inventor
  • Gomi, Tomohiro
  • Tomita, Sadamu
  • Umebayashi, Ryu
  • Yamashita, Okito
  • Takeda, Yusuke

Abstract

This method for suggesting the positioning of electromagnetic sensors involves suggesting the positioning of a plurality of electromagnetic sensors positioned on the surface of a living body around a target region inside a subject, using a forward model for estimating electromagnetic fields produced at the positions of the plurality of electromagnetic sensors by biological activity inside the subject, the method including: a step for setting calculation conditions including the position of the target region and the positions at which the plurality of electromagnetic sensors can be positioned; a step for calculating, on the basis of the calculation conditions that have been set, suggested positioning for all or some of the plurality of electromagnetic sensors, which are for estimating the position of a current source inside the subject; and a step for outputting the suggested positioning.

IPC Classes  ?

  • A61B 5/242 - Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents

18.

CALIBRANT FOR USE IN MASS SPECTROMETER AND METHOD FOR PRODUCING SAME

      
Application Number 18276323
Status Pending
Filing Date 2022-02-02
First Publication Date 2024-04-04
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Nishikaze, Takashi
  • Kaneko, Naoki

Abstract

A calibrant for use in correction of machine difference of mass spectrometers and a method for producing the calibrant are provided. A calibrant for use in a mass spectrometer, the calibrant comprising not less than two calibration substances, wherein a ratio of, relative to a concentration of one calibration substance of the not less than two calibration substances, a concentration of another calibration substance of the not less than two calibration substances is a predetermined value, and a method for producing the calibrant.

IPC Classes  ?

  • H01J 49/00 - Particle spectrometers or separator tubes

19.

ANALYSIS SYSTEM

      
Application Number JP2023016614
Publication Number 2024/070027
Status In Force
Filing Date 2023-04-27
Publication Date 2024-04-04
Owner SHIMADZU CORPORATION (Japan)
Inventor Yonekura Takuya

Abstract

An analysis system (1) comprises an analysis device (100) that analyzes samples. At least one of the constituent elements of the analysis device (100) is a temperature adjustment constituent element (106; 108) that includes a temperature adjustment element (112; 116) and a temperature sensor (112; 116). The temperature adjustment constituent element (106; 108) must perform temperature control by using the temperature adjustment element (112, 116) and the temperature sensor (112, 116) and stabilize the temperature at a set target temperature at the time of starting the analysis. The analysis device (100) enters an analysis-enabled state in which analysis can be started when the temperatures of all the temperature adjustment constituent elements (106; 108) stabilize at the temperature set for each. The analysis system (1) comprises: a time measurement unit (202) that is configured to measure, as stabilization times, the time required from the start of the temperature control until output of the temperature sensor (112; 116) stabilizes, every time the temperature control is executed; a data accumulation unit (204) that is configured to store and accumulate the stabilization times, which are measured by the time measurement unit (202) each time the temperature control is executed, in association with conditions that affect the stabilization times when the temperature control is executed; and a time prediction unit (206) that is configured to calculate a predicted value of the time required for the analysis device (100) to enter the analysis-enabled state, by using a large number of compatible stabilization times, from among the stabilization times accumulated by the data accumulation unit (204), in which the associated conditions are compatible with the conditions at the time of the setting, when the settings for the analysis are made.

IPC Classes  ?

20.

MASS SPECTROMETER AND POWER SUPPLY DEVICE

      
Application Number 18447640
Status Pending
Filing Date 2023-08-10
First Publication Date 2024-04-04
Owner SHIMADZU CORPORATION (Japan)
Inventor Mizutani, Shiro

Abstract

A power supply device applies a voltage to a quadrupole mass filter. The power supply device has a main substrate and a wave-detection substrate. The main substrate includes a detector. The wave-detection substrate includes a wave detector and an identifier. The wave detector detects an AC component of a voltage to be applied to the quadrupole mass filter as a wave-detection voltage. The identifier outputs identification information of the wave detector defined in correspondence with the configuration of a rectifying device of the wave detector. The detector detects identification information output by the identifier, and supplies the detected identification information to a corrector that corrects a deviation of voltage caused by a leakage current of the rectifying device.

IPC Classes  ?

  • H01J 49/00 - Particle spectrometers or separator tubes
  • H01J 49/02 - Particle spectrometers or separator tubes - Details
  • H01J 49/42 - Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons

21.

X-RAY PHASE IMAGING DEVICE AND X-RAY PHASE IMAGING ANALYSIS METHOD

      
Application Number JP2023028534
Publication Number 2024/070230
Status In Force
Filing Date 2023-08-04
Publication Date 2024-04-04
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Doki, Takahiro
  • Kimura, Kenji
  • Morimoto, Naoki
  • Nagai, Ishikawa, Lisa

Abstract

This X-ray phase imaging device (100) comprises: an X-ray light source (10), an X-ray detector (11), a plurality of lattices; a rotary mechanism (15) which rotates a subject (90) including fibers (91a) and the plurality of lattices relative to each other; an image processing unit (2a) which generates a plurality of X-ray phase contrast images (40) for each of the orientations of the subject with respect to the plurality of lattices; and a control unit (2b) which acquires orientation information (30) pertaining to the orientations of fibers included in the subject on the basis of the plurality of X-ray phase contrast images, and acquires a feature amount (31) pertaining to the mechanical strength of the subject.

IPC Classes  ?

  • G01N 23/041 - Phase-contrast imaging, e.g. using grating interferometers

22.

OPTIMIZATION METHOD FOR WORK SYSTEM, AND CONTROL SYSTEM

      
Application Number JP2023029396
Publication Number 2024/070282
Status In Force
Filing Date 2023-08-14
Publication Date 2024-04-04
Owner SHIMADZU CORPORATION (Japan)
Inventor Kurata, Seiya

Abstract

According to the present invention, a management device optimizes a work system. More specifically, this management device: sets a control parameter set that is made up of one or more parameters for controlling actions of the work system (step S10); controls the actions of the work system on the basis of the control parameter set (step S12); acquires an observation value relating to the work system in relation to execution of the actions based on the control parameter set (step S14); calculates a posterior distribution of a model function in which one or more parameters are variables by using the control parameter set and the observation value (step S20); and updates an optimization function for identifying an optimal parameter set as the control parameter set, using calculation results of the posterior distribution (step S24).

IPC Classes  ?

  • G06N 99/00 - Subject matter not provided for in other groups of this subclass

23.

TEST SCHEDULE MANAGEMENT METHOD AND MANAGEMENT DEVICE, AND TEST SCHEDULE MANAGEMENT PROGRAM

      
Application Number JP2023029399
Publication Number 2024/070283
Status In Force
Filing Date 2023-08-14
Publication Date 2024-04-04
Owner SHIMADZU CORPORATION (Japan)
Inventor Nimura, Risa

Abstract

Provided is a management method for a test schedule that includes a first step and a second step. The time slots for the first step include time slots for which work on the part of a worker is not required, and the time slots for the second step include time slots for which work on the part of a worker is required. When the second step is arranged in a portion of the first step in a test schedule, the second step is arranged in the test schedule such that time slots in the second step for which work on the part of a worker is required overlap only time slots in the first step for which work on the part of a worker is not required.

IPC Classes  ?

  • G06Q 10/0631 - Resource planning, allocation, distributing or scheduling for enterprises or organisations
  • G06Q 10/1093 - Calendar-based scheduling for persons or groups

24.

Mass spectrometer

      
Application Number 29815635
Grant Number D1020502
Status In Force
Filing Date 2021-11-16
First Publication Date 2024-04-02
Grant Date 2024-04-02
Owner SHIMADZU CORPORATION (Japan)
Inventor Kang, Hyeri

25.

MASS SPECTROMETER

      
Application Number 17768929
Status Pending
Filing Date 2020-08-11
First Publication Date 2024-03-28
Owner SHIMADZU CORPORATION (Japan)
Inventor Hosoo, Kohei

Abstract

A mass spectrometer includes: a first ion guide disposed in a first intermediate vacuum chamber; a first partition wall portion which constitutes at least a part of a partition wall separating the first intermediate vacuum chamber and a second intermediate vacuum chamber and has an ion passage hole; a second ion guide disposed in a second intermediate vacuum chamber; a second partition wall portion which constitutes at least a part of a partition wall which is a subsequent stage of the second intermediate vacuum chamber and has an ion passage hole; a first holding portion configured to integrally hold the first ion guide and the first partition wall portion; a second holding portion configured to hold the second ion guide; a coupling portion detachably connecting the first holding portion and the second holding portion; and a vacuum chamber main body portion to which an ion transport unit is detachably mounted.

IPC Classes  ?

  • H01J 49/06 - Electron- or ion-optical arrangements
  • H01J 49/24 - Vacuum systems, e.g. maintaining desired pressures

26.

X-RAY PHASE IMAGING APPARATUS AND DISPLAY METHOD OF PREVIEW IMAGE IN X-RAY PHASE IMAGING APPARATUS

      
Application Number 18355557
Status Pending
Filing Date 2023-07-20
First Publication Date 2024-03-28
Owner Shimadzu Corporation (Japan)
Inventor
  • Kojima, Kana
  • Maeda, Yuto
  • Doki, Takahiro

Abstract

An X-ray phase imaging apparatus includes an X-ray source; a detector; a plurality of gratings; a rotation mechanism; an image processor configured to generate a phase contrast image and to generate a preview image prior to capture of the phase contrast image; and a controller configured to control function of displaying on a display the preview image, and function of discriminatively displaying on the display an image coverage area for the phase contrast image that is associated with a relative rotation angle between the plurality of gratings and a subject.

IPC Classes  ?

  • G01N 23/041 - Phase-contrast imaging, e.g. using grating interferometers
  • G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
  • G01N 23/201 - Measuring small-angle scattering, e.g. small angle X-ray scattering [SAXS]

27.

X-RAY PHASE IMAGING APPARATUS AND X-RAY PHASE IMAGING METHOD

      
Application Number 18363168
Status Pending
Filing Date 2023-08-01
First Publication Date 2024-03-28
Owner Shimadzu Corporation (Japan)
Inventor
  • Kojima, Kana
  • Maeda, Yuto

Abstract

An X-ray phase imaging apparatus includes a control device configured or programmed to make a notification prompting a user to update or generate a corresponding second X-ray image when determining that a decrease in an image quality of an X-ray phase contrast image generated based on a first X-ray image obtained by imaging a subject and a second X-ray image obtained by imaging without the subject arranged does not fall within a predetermined allowable range and/or determining that the second X-ray image associated with an imaging condition has not been stored.

IPC Classes  ?

  • G01N 23/041 - Phase-contrast imaging, e.g. using grating interferometers
  • G01N 23/083 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and measuring the absorption the radiation being X-rays

28.

DIFFERENTIAL ION MOBILITY SPECTROMETRY

      
Application Number EP2022076483
Publication Number 2024/061469
Status In Force
Filing Date 2022-09-23
Publication Date 2024-03-28
Owner
  • SHIMADZU CORPORATION (Japan)
  • SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
Inventor
  • Andrzejewski, Roch
  • Giles, Roger

Abstract

EDD TPNTPRREDD NTPRR, is compared to a pre-set target ratio value and, if the comparison reveals a difference therebetween, an adjusted value of the dispersion electric field sufficient reduce the difference is applied across the analytical gap.

IPC Classes  ?

  • G01N 27/624 - Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
  • G01N 27/623 - Ion mobility spectrometry combined with mass spectrometry

29.

GAS CHROMATOGRAPH AND CARRIER GAS USAGE AMOUNT DISPLAY METHOD

      
Application Number 18354013
Status Pending
Filing Date 2023-07-18
First Publication Date 2024-03-28
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Sakamoto, Yuki
  • Nagao, Yu

Abstract

A gas chromatograph includes a sample gas generator, a separation column configured to separate components of an introduced sample gas, a gas supply source configured to supply a carrier gas to the sample gas generator to carry the sample gas from the sample gas generator to the separation column when the components of the sample gas are analyzed, a controller configured or programmed to acquire an in-analysis usage amount of the carrier gas based on an analysis time for analyzing the components of the sample gas, and a flow rate of the carrier gas supplied from the gas supply source to the sample gas generator, and a display configured to display the in-analysis usage amount acquired by the controller.

IPC Classes  ?

  • G01N 30/32 - Control of physical parameters of the fluid carrier of pressure or speed

30.

X-RAY PHASE IMAGING APPARATUS AND DISPLAY METHOD OF PREVIEW IMAGE IN X-RAY PHASE IMAGING APPARATUS

      
Application Number 18357287
Status Pending
Filing Date 2023-07-24
First Publication Date 2024-03-28
Owner Shimadzu Corporation (Japan)
Inventor
  • Maeda, Yuto
  • Kojima, Kana

Abstract

An X-ray phase imaging apparatus includes an X-ray source; a detector; a plurality of gratings; an image processor configured to generate two or more types of first phase contrast images selected from absorption, differential phase and dark-field images as preview images under an imaging condition simpler than an imaging condition for a second phase contrast image to be captured in actual imaging; and a controller configured to display the first phase contrast images on a display.

IPC Classes  ?

  • A61B 6/00 - Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment

31.

MASS SPECTROMETRY METHOD AND MASS SPECTROMETER

      
Application Number 17767946
Status Pending
Filing Date 2019-11-11
First Publication Date 2024-03-28
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Takahashi, Hidenori
  • Sekiya, Sadanori
  • Yamauchi, Shosei

Abstract

First product ion spectrum data is acquired by dissociating a precursor ion derived from a sample component by collision between the precursor ion and an inert gas molecule to generate product ions, and detecting the product ions after separating the product ions according to a mass-to-charge ratio; second product ion spectrum data is acquired by dissociating the precursor ion by a reaction of the precursor ion with hydrogen radicals to generate product ions, and detecting the product ions after separating the product ions according to a mass-to-charge ratio; and a set of product ions having a predetermined mass difference is extracted in the first product ion spectrum data and the second product ion spectrum data.

IPC Classes  ?

  • G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
  • H01J 49/26 - Mass spectrometers or separator tubes

32.

DIFFERENTIAL ION MOBILITY ANALYSIS

      
Application Number EP2022076480
Publication Number 2024/061468
Status In Force
Filing Date 2022-09-23
Publication Date 2024-03-28
Owner
  • SHIMADZU CORPORATION (Japan)
  • SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
Inventor
  • Andrzejewski, Roch
  • Giles, Roger
  • Entwistle, Andrew

Abstract

A method of analyzing ions comprising generating ions from a sample in an ion source, delivering them into a vacuum region of a vacuum enclosure comprising an ion mobility analyser having an ion drift region formed between opposing electrodes defining an analytical gap. The ions emerge from the ion inlet as a supersonic jet of a buffer gas within which the ions are entrained to enter the drift region and, e.g., priorto mass spectral analysis of the ions in a downstream vacuum region, conducting differential ion mobility analysis of the ions in the first vacuum region. Priorto conducting differential ion mobility analysis (e.g., and mass spectral analysis) according of the ion, the method comprises a) changing a rate of flow of gas into or out of the vacuum region; b) measuring a gas pressure in the vacuum region and repeating steps a) and b) until a target gas pressure value is achieved; c) measuring a velocity of gas flow along the drift region and repeating steps a) to c) until the measured gas velocity value has achieved a pre-set target gas velocity value and subsequently conducting said differential ion mobility analysis and said mass spectral analysis according to said target gas pressure value and said target gas velocity value.

IPC Classes  ?

  • G01N 27/624 - Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
  • G01N 27/623 - Ion mobility spectrometry combined with mass spectrometry

33.

DEBINDING RECIPE SETTING METHOD

      
Application Number JP2023025007
Publication Number 2024/062731
Status In Force
Filing Date 2023-07-05
Publication Date 2024-03-28
Owner SHIMADZU CORPORATION (Japan)
Inventor Tanaka, Suguru

Abstract

The present invention is capable of setting a debinding recipe with low power consumption and in a short period of time, and minimizes time consumption and energy loss in an actual debinding treatment performed according to the set recipe. The present invention performs: a data accumulation step for associating existing treatment target analysis data that is obtained by using a differential thermal measurement device, a thermogravimetry device, and/or a thermomechanical analysis device to analyze part of an existing treatment target with debinding result data that indicates the result of debinding the existing treatment target in a debinding furnace, and for accumulating the data in a memory; an analysis step for analyzing, on the basis of the existing treatment target analysis data and the debinding result data which are accumulated in a data accumulation unit, new treatment target analysis data that is obtained by using the differential thermal measurement device, the thermogravimetry device, and/or the thermomechanical analysis device 300 to analyze part of a new treatment target; and a recipe setting step for setting a debinding recipe for the new treatment target on the basis of the analysis result in the analysis step.

IPC Classes  ?

  • C04B 35/638 - Removal thereof
  • B28B 11/00 - Apparatus or processes for treating or working the shaped articles
  • G01N 25/20 - Investigating or analysing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity

34.

Total organic carbon meter

      
Application Number 29758221
Grant Number D1019441
Status In Force
Filing Date 2020-11-13
First Publication Date 2024-03-26
Grant Date 2024-03-26
Owner SHIMADZU CORPORATION (Japan)
Inventor Hasebe, Shinya

35.

SIGNAL PROCESSING DEVICE FOR X-RAY ANALYSIS

      
Application Number 18274611
Status Pending
Filing Date 2021-07-29
First Publication Date 2024-03-21
Owner SHIMADZU CORPORATION (Japan)
Inventor Saito, Yuta

Abstract

Provided is a signal processing device for X-ray analysis capable of suppressing effects of increased background due to pile-up signals and suppressing the dead time from lengthening. A signal processing device for X-ray analysis includes a differentiating circuit configured to convert a plurality of staircase wave signals detected by the X-ray detector into differential wave signals, a digital filter configured to convert the differential wave signals into trapezoidal wave signals or triangular wave digital signals, and a peak detection unit configured to discriminate and count a peak value extracted from a peak portion of the trapezoidal wave signal or the triangular wave signal. The peak detection unit is set such that a rising threshold Tu to be compared with a signal of the rising-side sloped line segment and a falling threshold Td to be compared with a signal of the falling-side sloped line segment in the trapezoidal signal or the triangular wave signal have a relation of Tu>Td. The peak detection unit selects the trapezoidal signal or the triangular wave signal to be counted from the converted trapezoidal signal or the converted triangular wave signal based on the rising threshold Tu, and terminates detection of the peak portion of the trapezoidal signal or the triangular wave signal based on the falling threshold Td.

IPC Classes  ?

  • G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence

36.

Raman Infrared Compound Microscope Device

      
Application Number 18214507
Status Pending
Filing Date 2023-06-26
First Publication Date 2024-03-21
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Katsutani, Fumiya
  • Sasayama, Tomoki
  • Tao, Tomoyo
  • Otaguro, Atsuhiko
  • Shibutani, Ryuta
  • Fukuda, Hisato

Abstract

A Raman infrared compound microscope device includes: a first light source that generates laser light; a second light source that generates infrared light; a third light source that generates visible light; and a first optical system. The first optical system orients the visible light having reached the first optical system in different directions between when performing a Raman analysis using Raman light generated from a sample by irradiation of the laser light and when performing a first infrared analysis using the infrared light having passed through the sample.

IPC Classes  ?

  • G01N 21/65 - Raman scattering
  • G01J 3/02 - Spectrometry; Spectrophotometry; Monochromators; Measuring colours - Details
  • G01J 3/10 - Arrangements of light sources specially adapted for spectrometry or colorimetry
  • G01J 3/44 - Raman spectrometry; Scattering spectrometry
  • G02B 21/06 - Means for illuminating specimen

37.

METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND

      
Application Number 18271386
Status Pending
Filing Date 2021-09-22
First Publication Date 2024-03-21
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Shima, Keisuke
  • Fukuyama, Yuko

Abstract

The present invention provides a method for mass spectrometry of a negatively charged organic synthetic compound, and a matrix that can be used in said method. A method for mass spectrometry of a negatively charged organic synthetic compound, the method comprising using, as a liquid matrix, an ionic liquid comprising an amine ion and an acidic group-containing organic substance ion. For example, the amine is 3-aminoquinoline (3-AQ), and the acidic group-containing organic substance is p-coumaric acid (p-CA). The negatively charged organic synthetic compound to be analyzed is, for example, an organic synthetic polymer compound or a complex compound.

IPC Classes  ?

  • H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
  • G01N 30/84 - Preparation of the fraction to be distributed

38.

METHOD FOR CONTROLLING MOBILE OBJECT, TRANSPORT DEVICE, AND WORK SYSTEM

      
Application Number JP2023029395
Publication Number 2024/057800
Status In Force
Filing Date 2023-08-14
Publication Date 2024-03-21
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Imai, Shinji
  • Takahara, Kazuma

Abstract

A management device (100) performs, as a method for controlling a mobile object: a step for generating a machine learning model for generating an operation plan for a mobile object for transporting an object, on the basis of the position of a first feature portion in a simulation space; a step for identifying the position of a second feature portion in the real space; a step for acquiring the relationship between the position of the second feature portion in the real space and a position in the real space corresponding to the position of the first feature portion in the simulation space; a step for applying the position of the second feature portion in the real space and the relationship to the machine learning model, to thereby generate an operation plan for the mobile object; and a step for controlling the operation of the mobile object in accordance with the generated operation plan.

IPC Classes  ?

  • B25J 9/22 - Recording or playback systems
  • G05D 1/00 - Control of position, course, altitude, or attitude of land, water, air, or space vehicles, e.g. automatic pilot

39.

CONTROL METHOD FOR CONTROLLING TRANSPORT OF OBJECT, TRANSPORT DEVICE FOR TRANSPORTING OBJECT, AND WORK SYSTEM PROVIDED WITH TRANSPORT DEVICE

      
Application Number JP2023030106
Publication Number 2024/057836
Status In Force
Filing Date 2023-08-22
Publication Date 2024-03-21
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Takahara, Kazuma
  • Imai, Shinji

Abstract

This control method uses an image captured by an image capturing unit (234) to control transport of an object to a target position by using a first moving body (232). The control method comprises: a step for performing proximity control for causing the image capturing unit (234) to be in relative proximity to a characteristic part indicating a reference position different from the target position; a step for causing the image capturing unit (234), which has been put in relative proximity to the characteristic part by the proximity control, to acquire a first image obtained by photographing the characteristic part; and a step for causing the first moving body (232) to transport the object to the target position on the basis of the first image.

IPC Classes  ?

  • B25J 13/08 - Controls for manipulators by means of sensing devices, e.g. viewing or touching devices

40.

JETANIZER

      
Serial Number 98453342
Status Pending
Filing Date 2024-03-17
Owner SHIMADZU CORPORATION (Japan)
NICE Classes  ? 09 - Scientific and electric apparatus and instruments

Goods & Services

Measuring apparatus and instruments, namely, a chemical reactor that converts carbon dioxide and carbon monoxide to methane for analyzing chromatograph elution; gas chromatography apparatus

41.

AUTOMATIC DISPENSING DEVICE

      
Application Number 18215023
Status Pending
Filing Date 2023-06-27
First Publication Date 2024-03-14
Owner Shimadzu Corporation (Japan)
Inventor Miyazaki, Koki

Abstract

An automatic dispensing device includes a gripper configured to grip a dispenser having a discharge nozzle with the discharge nozzle facing downward, a tip rack arrangement portion configured to arrange a tip rack in which pipette tips to be attached to the discharge nozzle are accommodated, a biasing member configured to bias the tip rack arrangement portion from below, and a moving unit configured to move the gripper relative to the tip rack arrangement portion.

IPC Classes  ?

42.

PRESSURE SENSOR

      
Application Number 18241674
Status Pending
Filing Date 2023-09-01
First Publication Date 2024-03-14
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Takebayashi, Ryu
  • Imamura, Shinya

Abstract

A sheet-like diaphragm made from a non-metallic material, a main body block made from a non-metallic material, having a diaphragm facing surface facing a main plane of the diaphragm, disposed in a manner that the diaphragm facing surface is covered by the diaphragm, and provided with a fluid outlet and a fluid inlet facing the diaphragm side, a sensor head that has a recess for accommodating pressure transmission liquid, is disposed on a side opposite to the main body block across the diaphragm such that an opening of the recess is closed by the diaphragm, and is configured to detect pressure of fluid flowing between the diaphragm and the diaphragm facing surface by a deformation amount of the diaphragm are included. The fluid inlet and the fluid outlet are provided in a manner separated from the diaphragm further than the diaphragm facing surface.

IPC Classes  ?

  • G01L 9/00 - Measuring steady or quasi-steady pressure of a fluid or a fluent solid material by electric or magnetic pressure-sensitive elements; Transmitting or indicating the displacement of mechanical pressure-sensitive elements, used to measure the steady or quasi-steady pressure of a fluid or fluent solid material, by electric or magnetic means
  • G01N 30/32 - Control of physical parameters of the fluid carrier of pressure or speed

43.

CHROMATOGRAPH

      
Application Number 18272707
Status Pending
Filing Date 2021-09-09
First Publication Date 2024-03-14
Owner Shimadzu Corporation (Japan)
Inventor Inohana, Yusuke

Abstract

A chromatograph including: a column 13 configured to separate a compound contained in a sample; a detection unit 2 configured to measure a predetermined physical quantity of the compound flowing out of the column; a measurement condition storage unit 411 in which one or a plurality of measurement conditions are stored; a measurement control unit 423 configured to set an operation of measuring each of a plurality of samples using any one of the measurement conditions stored in the measurement condition storage unit a plurality of times for each sample and execute all measurement operations set for the plurality of samples in random order; and a measurement data processing unit 424 configured to associate measurement data acquired by the detection unit with a sample to be measured for each measurement.

IPC Classes  ?

44.

X-RAY FLUORESCENCE ANALYSIS DEVICE

      
Application Number 18274617
Status Pending
Filing Date 2021-07-29
First Publication Date 2024-03-14
Owner SHIMADZU CORPORATION (Japan)
Inventor Saito, Yuta

Abstract

Provided is an X-ray fluorescence analyzer capable of performing an analysis under more favorable conditions depending on an analysis target. The X-ray fluorescence analyzer includes a detector 30, preamplifiers 41A, 41B configured to amplify a detection signal from the detector into a staircase wave signal at different signal amplification factors GA, GB, a differentiating circuit 42 configured to convert the staircase wave signal into a differential wave signal, an A/D converter 43 configured to convert the differential wave digital signal to a digital signal, a signal processing unit 160 configured to detect a peak value from the digital signal, discriminate and count the peak value, and generate a histogram, and an input unit 51 configured to set the energy range of the fluorescent X-rays to be analyzed. Any one of the preamplifiers is automatically selected based on maximum energy in the set energy range.

IPC Classes  ?

  • G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence

45.

METHOD FOR DRIVING LINEAR ION TRAP AND MASS SPECTROMETER

      
Application Number 18348753
Status Pending
Filing Date 2023-07-07
First Publication Date 2024-03-14
Owner SHIMADZU CORPORATION (Japan)
Inventor Nishiguchi, Masaru

Abstract

A method for driving a linear ion trap having rod electrodes arranged so as to surround a central axis includes: an ion-introducing step for introducing ions into an ion-capturing space surrounded by the rod electrodes, and for capturing the ions by a multipole RF electric field created within the ion-capturing space; and an ion-ejecting step for creating both a DC electric field for ion extraction extending from an external area outside the ion-capturing space into the ion-capturing space through a space between two predetermined rod electrodes neighboring each other around the central axis among the plurality of rod electrodes and the multipole RF electric field, and for sequentially ejecting ions according to their m/z from the ion-capturing space toward the external area through the space between the two predetermined rod electrodes by changing at least one of the multipole RF electric field and the DC electric field.

IPC Classes  ?

  • H01J 49/42 - Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons

46.

AUTOMATIC DISPENSING DEVICE

      
Application Number 18139133
Status Pending
Filing Date 2023-04-25
First Publication Date 2024-03-14
Owner Shimadzu Corporation (Japan)
Inventor Miyazaki, Koki

Abstract

An automatic dispensing device is provided with a sample container holder having a plurality of recesses, each of the recessed being configured to accommodate a sample container, a biasing member provided in each of the plurality of recesses, the biasing member being configured to bias the sample container accommodated in the recess upward, and a liquid dispensing mechanism having a discharge pipe for discharging a liquid from a tip end, the liquid dispensing mechanism being configured to discharge the liquid in a state in which the tip end of the discharge pipe is pressed against an inner part of the sample container at a predetermined dispensing target position from above.

IPC Classes  ?

  • G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor

47.

ANALYZER AND DISPLAY METHOD

      
Application Number 18243966
Status Pending
Filing Date 2023-09-08
First Publication Date 2024-03-14
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Ogino, Kota
  • Harada, Akira

Abstract

An analyzer that analyzes one or more pieces of data acquired by electrophoresis separation of a sample includes a memory, a display unit, and a processor. The memory stores the one or more pieces of data. The display unit displays, based on the one or more pieces of data, a gel image, an electropherogram, a first size guide corresponding to the gel image, and a second size guide corresponding to the electropherogram. When the first size guide is located at a first position corresponding to a specific value associated with a size in the gel image, the processor displays a second size guide at a second position corresponding to the specific value in the electropherogram.

IPC Classes  ?

  • G06T 11/20 - Drawing from basic elements, e.g. lines or circles
  • G01N 27/447 - Systems using electrophoresis
  • G06F 3/04845 - Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range for image manipulation, e.g. dragging, rotation, expansion or change of colour

48.

QUADRUPOLE MASS SPECTROMETER

      
Application Number 18559161
Status Pending
Filing Date 2021-05-31
First Publication Date 2024-03-14
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Ueda, Manabu
  • Miyashiro, Hiroki
  • Taniguchi, Junichi

Abstract

A quadrupole mass spectrometer includes a quadrupole mass filter including: a main rod portion including four main rod electrodes; a pre-rod portion including four pre-rod electrodes, where, at an end opposite to the main rod portion, the four pre-rod electrodes are disposed to be aligned on an inscribed circle having the same radius centered on the ion optical axis, and, at the other end facing the main rod portion, two pre-rod electrodes facing each other across the ion optical axis and the other two pre-rod electrodes are disposed to be aligned on an inscribed circle having different radii centered on the ion optical axis; a main voltage applying unit to apply, to each main rod electrodes, a voltage created by superimposing a DC voltage and an RF voltage; and a pre-voltage applying unit to apply an RF voltage having a same frequency as the RF voltage to each pre-rod electrodes.

IPC Classes  ?

  • H01J 49/42 - Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons

49.

MICROCHANNEL DEVICE

      
Application Number 18237530
Status Pending
Filing Date 2023-08-24
First Publication Date 2024-03-07
Owner SHIMADZU CORPORATION (Japan)
Inventor Takeuchi, Ippei

Abstract

A microchannel device includes an opening that receives a test solution, a main channel that communicates with the opening, and a collection portion provided at an outlet-side end of the main channel. The collection portion includes a pool that stores the test solution, a connection channel that connects the pool with the outlet-side end, and a protrusion that is arranged in the connection channel to generate air bubbles between the protrusion and an inner wall of the connection channel to close the connection channel, upon receiving the test solution discharged from the main channel.

IPC Classes  ?

  • B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

50.

X-RAY FLUOROSCOPIC DEVICE

      
Application Number JP2023017041
Publication Number 2024/047943
Status In Force
Filing Date 2023-05-01
Publication Date 2024-03-07
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Matsuda Kazuyuki
  • Tsutsumida Yumi

Abstract

The present invention comprises a rotatable C-arm 17 that supports and causes an X-ray tube 13 and an X-ray detector 15 to face each other, an image generating unit 43 that uses a detected signal of the x-ray detector 15 to generate an X-ray image L, and an image display device 11 that displays the X-ray image L. The image display device 11 comprises: an image display unit 49 capable of displaying information display images D in parallel in a matrix shape; an input unit 51 for inputting an instruction for changing the position where image information K is displayed in the information display images D so that at least two X-ray images L are displayed adjacent to each other among the information display images D; and an image display control unit 57 that controls the image display unit 49 so that the X-ray images L are displaced adjacent to each other, on the basis of the content of the instruction.

IPC Classes  ?

  • A61B 6/00 - Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment

51.

MASS SPECTROMETER

      
Application Number 18203356
Status Pending
Filing Date 2023-05-30
First Publication Date 2024-03-07
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Okamura, Shinichiro
  • Nishiguchi, Masaru

Abstract

An ion transport optical system includes N rod electrodes forming an N-pole arrangement externally tangent to a circle of diameter A1 at an ion-entrance end, where N is an even number not smaller than six. Four electrodes form a quadrupole arrangement externally tangent to a circle of diameter A2 at an ion-exit end, where A2

IPC Classes  ?

  • H01J 49/06 - Electron- or ion-optical arrangements
  • H01J 49/00 - Particle spectrometers or separator tubes
  • H01J 49/42 - Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons

52.

MICROORGANISM IDENTIFICATION METHOD

      
Application Number 18221829
Status Pending
Filing Date 2023-07-13
First Publication Date 2024-03-07
Owner
  • SHIMADZU Corporation (Japan)
  • Meijo University (Japan)
Inventor
  • Tamura, Hiroto
  • Yamamoto, Naomi
  • Kato, Teruyo
  • Shima, Keisuke
  • Funatsu, Shinji

Abstract

Provided is a non-transitory computer-readable medium storing a program for causing a computer to execute the steps including a step of subjecting a sample containing microorganisms to mass spectrometry to obtain a mass spectrum, a step of reading a mass-to-charge ratio m/z of a peak derived from a marker protein from the mass spectrum, and an identification step of identifying which bacteria of serovar of Salmonella genus bacteria the microorganisms contained in the sample contain, based on the mass-to-charge ratio m/z, wherein at least one of two types of ribosomal proteins S8 and Peptidylpropyl isomerase is used as the marker protein.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
  • G01N 27/64 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using wave or particle radiation to ionise a gas, e.g. in an ionisation chamber

53.

ION CHROMATOGRAPHY ANALYSIS SYSTEM

      
Application Number 18241090
Status Pending
Filing Date 2023-08-31
First Publication Date 2024-03-07
Owner SHIMADZU CORPORATION (Japan)
Inventor Yonekura, Takuya

Abstract

An ion chromatography analysis system includes a system monitoring part being configured to detect an abnormality, to determine, based on a fluctuation rate in a certain time of the predetermined state of a most recent of the monitor value, whether the fluctuation is a short-term fluctuation that occurs in a short term or a long-term fluctuation that occurs in a long term, and to identify a cause of the abnormality by using whether the fluctuation is the short-term fluctuation or the long-term fluctuation.

IPC Classes  ?

  • G01N 30/32 - Control of physical parameters of the fluid carrier of pressure or speed
  • B01D 15/14 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
  • B01D 15/36 - Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
  • G01N 30/14 - Preparation by elimination of some components
  • G01N 30/16 - Injection
  • G01N 30/64 - Electrical detectors

54.

CELL CULTURE CONTAINER AND CELL CULTURE DEVICE

      
Application Number 18268670
Status Pending
Filing Date 2021-10-14
First Publication Date 2024-03-07
Owner Shimadzu Corporation (Japan)
Inventor
  • Inoue, Tsunehiro
  • Hashimoto, Toyoyuki
  • Yoneda, Yasuko
  • Takubo, Kenji
  • Fujiyama, Yoichi
  • Ohkubo, Tomoki
  • Ozeki, Eiichi
  • Takai, Ryogo
  • Goto, Hiroomi
  • Tomita, Sadamu

Abstract

A cell culture container includes: an insert member having a membrane on which a cell is seeded, the insert member defining a first inner space that functions as an anaerobic chamber; a container having an attachment/detachment portion to and from which the insert member is attachable and detachable, the container defining a second inner space that functions as an aerobic chamber; a sealing member that closes an opening of the aerobic chamber between the attachment/detachment portion and the insert member with the insert member being attached to the attachment/detachment portion; and a transfer mechanism that transfers force to the sealing member. The sealing member closes the opening in response to an input of the force from the transfer mechanism.

IPC Classes  ?

  • C12M 1/00 - Apparatus for enzymology or microbiology
  • C12M 1/12 - Apparatus for enzymology or microbiology with sterilisation, filtration, or dialysis means

55.

METHOD FOR ANALYZING METABOLITE OF MICROORGANISM

      
Application Number 18273856
Status Pending
Filing Date 2022-01-17
First Publication Date 2024-03-07
Owner
  • SHIMADZU CORPORATION (Japan)
  • NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (Japan)
  • AJINOMOTO CO., INC. (Japan)
Inventor
  • Horie, Shinnosuke
  • Fujito, Yuka
  • Hasunuma, Tomohisa
  • Yoshida, Takanobu
  • Urahata, Erika

Abstract

Provided is a method capable of shortening the time required for analysis and capable of analyzing various substances produced by microorganisms. A method for analyzing a metabolite of a microorganism according to the present invention includes: a step of supplying a mobile phase including carbon dioxide in a liquid state, a subcritical state, or a supercritical state to a container in which a microorganism cultured in a medium is contained together with the medium, to move a component of a metabolite of the microorganism present in the microorganism and the medium to the mobile phase; a step of introducing a mobile phase to which a component of the metabolite has moved into a column; and a step of performing mass spectrometry on a component of the metabolite contained in the mobile phase that has passed through the column.

IPC Classes  ?

  • G01N 30/72 - Mass spectrometers
  • C12N 1/20 - Bacteria; Culture media therefor
  • G01N 30/04 - Preparation or injection of sample to be analysed
  • G01N 30/26 - Conditioning of the fluid carrier; Flow patterns

56.

MAINTENANCE SYSTEM, MANAGEMENT DEVICE, AND MAINTENANCE METHOD

      
Application Number JP2023025654
Publication Number 2024/048087
Status In Force
Filing Date 2023-07-12
Publication Date 2024-03-07
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Kinoshita, Naoki
  • Isobe, Seiyu
  • Takezawa, Hidetaka

Abstract

Provided is a maintenance system wherein a management device manages a database, which stores solution information associated with the state of a medical device, and updates the database. The management device receives state information indicating the state of the medical device from the medical device, which is connected to a network of an organization, via a network outside of the organization. The management device determines solution information corresponding to the state of the medical device on the basis of the state information and the database and transmits the determined solution information to a terminal device having a display unit via the network outside of the organization.

IPC Classes  ?

  • G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades

57.

X-RAY PHASE IMAGING SYSTEM AND X-RAY PHASE IMAGING METHOD

      
Application Number JP2023028519
Publication Number 2024/048200
Status In Force
Filing Date 2023-08-04
Publication Date 2024-03-07
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Nagai, Ishikawa, Lisa
  • Doki, Takahiro
  • Morimoto, Naoki

Abstract

This X-ray phase imaging system (100) comprises: an imaging system (6) including an X-ray source (1), an X-ray detector (2), and a plurality of lattices; a first rotation mechanism (7) which relatively rotates a subject (90) and the imaging system; an image processing unit (81) which generates a three-dimensional dark field-of-view image (43); a filter processing unit (82) which performs a filter process for extracting linear portions (44) included in the subject at a plurality of angles; and a linear portion image generation unit (83) which generates a linear portion image (45) on the basis of the plurality of linear portions corresponding to a fiber (90b).

IPC Classes  ?

  • G01N 23/041 - Phase-contrast imaging, e.g. using grating interferometers

58.

PROBE ASSESSMENT METHOD AND SPM

      
Application Number 18268299
Status Pending
Filing Date 2021-06-09
First Publication Date 2024-02-29
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Arai, Hiroshi
  • Nakajima, Hideo
  • Yamasaki, Kenji
  • Iida, Eiji
  • Kogure, Akinori

Abstract

A method of assessing a probe by measuring a known sample whose shape is known with the probe in an electronic microscope, the known sample having a projection part on a surface thereof, and the projection part having a shape tapered toward a vertex thereof, the method comprising a step of measuring circle equivalent radius of the projection part, a step of comparing the circle equivalent radius with a first threshold value, and a step of determining that the probe is satisfactory when the width is less than the first threshold value, and a step of determining that the probe is unsatisfactory when the width is equal to or greater than the first threshold value.

IPC Classes  ?

  • G01Q 40/02 - Calibration standards or methods of fabrication thereof

59.

X-RAY IMAGING SYSTEM AND LEARNED MODEL PRODUCTION METHOD

      
Application Number 18363144
Status Pending
Filing Date 2023-08-01
First Publication Date 2024-02-29
Owner Shimadzu Corporation (Japan)
Inventor
  • Tsushima, Hiroaki
  • Sawada, Ryuji

Abstract

An X-ray imaging system is configured to acquire first and second images from a teacher X-ray image including an inspection target. Discrimination information to discriminate at least one of an area of the inspection target in the first and second images, and an area of a defect part is acquired. Machine learning for producing a learned model is performed by using input teacher data sets based on the first and second images, and output teacher data sets based on the discrimination information.

IPC Classes  ?

  • G01N 23/04 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material
  • G06T 7/00 - Image analysis

60.

X-RAY IMAGING DEVICE

      
Application Number JP2023022178
Publication Number 2024/042823
Status In Force
Filing Date 2023-06-15
Publication Date 2024-02-29
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Matsuda, Kazuyuki
  • Watanabe, Ryusuke
  • Tanaka, Fumiaki
  • Yoshida, Koki

Abstract

This X-ray imaging device (100) comprises a first arm (1), a second arm (2), an imaging angle setting unit (4) for setting the respective target imaging angles of a first X-ray source (1a) and a second X-ray source (2a), and a display unit (3). The display unit (3) displays a disposition screen (8) indicating the disposition corresponding to the positions of both the first X-ray source (1a) and the second X-ray source (2a) at the target imaging angles with respect to the position of an actual subject (101). The imaging angle setting unit (4) and the display unit (3) are provided in the same disposition region (103) of an X-ray imaging device body (100a).

IPC Classes  ?

  • A61B 6/00 - Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment

61.

PRETREATMENT METHOD AND MASS SPECTROMETRY METHOD

      
Application Number JP2023030477
Publication Number 2024/043304
Status In Force
Filing Date 2023-08-24
Publication Date 2024-02-29
Owner
  • SHIMADZU CORPORATION (Japan)
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
  • Teramoto, Kanae
  • Sekiguchi, Yuji

Abstract

Provided is a mass-spectrometry pretreatment method for a sample containing cells, the method including: a step for bringing the cells into contact with a first acidic solution containing an organic acid; and a step for extracting cytoplasmic components of the cells by heating the cells and the first acidic solution in the state in which said materials are in contact with each other.

IPC Classes  ?

  • G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
  • C12N 1/06 - Lysis of microorganisms
  • C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers

62.

METHOD FOR DETECTING PARTICULATE SUBSTANCE BY IMMUNOCHROMATOGRAPHY, AND KIT FOR THE SAME

      
Application Number 18265816
Status Pending
Filing Date 2021-12-07
First Publication Date 2024-02-22
Owner
  • DAI NIPPON TORYO CO., LTD. (Japan)
  • SHIMADZU CORPORATION (Japan)
Inventor
  • Miyazawa, Yuta
  • Fujimoto, Hirotaka
  • Watanabe, Makoto
  • Sato, Taka-Aki

Abstract

An object of the present invention is to provide a method for detecting particulate substances with a high degree of sensitivity, while suppressing the generation of non-specific signals. According to the present invention, the generation of non-specific signals in the background can be suppressed by blocking a membrane of a test strip which is used for immunochromatography with a blocking composition including a polymer-based blocking agent having, in its side chain, a substituent represented by the following formula: An object of the present invention is to provide a method for detecting particulate substances with a high degree of sensitivity, while suppressing the generation of non-specific signals. According to the present invention, the generation of non-specific signals in the background can be suppressed by blocking a membrane of a test strip which is used for immunochromatography with a blocking composition including a polymer-based blocking agent having, in its side chain, a substituent represented by the following formula: An object of the present invention is to provide a method for detecting particulate substances with a high degree of sensitivity, while suppressing the generation of non-specific signals. According to the present invention, the generation of non-specific signals in the background can be suppressed by blocking a membrane of a test strip which is used for immunochromatography with a blocking composition including a polymer-based blocking agent having, in its side chain, a substituent represented by the following formula: (wherein R1, R2, and R3 are each independently a hydrogen atom, a C1-6 alkyl group, or a C1-6 hydroxyalkyl group; and n is an integer of 1 to 4), and having a weight average molecular weight (Mw) of 1×103 to 1×107.

IPC Classes  ?

  • G01N 33/574 - Immunoassay; Biospecific binding assay; Materials therefor for cancer
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

63.

MICROORGANISM IDENTIFICATION METHOD

      
Application Number 18221835
Status Pending
Filing Date 2023-07-13
First Publication Date 2024-02-22
Owner
  • SHIMADZU CORPORATION (Japan)
  • MEIJO UNIVERSITY (Japan)
Inventor
  • Tamura, Hiroto
  • Yamamoto, Naomi
  • Kato, Teruyo
  • Shima, Keisuke
  • Funatsu, Shinji

Abstract

Provided is a method of identifying a serovar of Salmonella bacteria including a step of subjecting a sample containing microorganisms to mass spectrometry to obtain a mass spectrum, a step of reading a mass-to-charge ratio m/z of a peak derived from a marker protein from the mass spectrum, and an identification step of identifying a serovar of Salmonella bacteria in the sample, based on the mass-to-charge ratio m/z, wherein the serovars of Salmonella bacteria are classified using cluster analysis using as an index the mass-to-charge ratio m/z derived from at least 12 types of ribosomal proteins S8, L15, L17, L21, L25, S7, SODa, peptidylprolyl isomerase, gns, YibT, YaiA and YciF as the marker proteins.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
  • G01N 27/64 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using wave or particle radiation to ionise a gas, e.g. in an ionisation chamber

64.

ANALYSIS METHOD

      
Application Number 18266977
Status Pending
Filing Date 2021-12-01
First Publication Date 2024-02-15
Owner SHIMADZU CORPORATION (Japan)
Inventor Kaneko, Naoki

Abstract

An analysis method includes a humidity measurement step of measuring humidity; a binding step of bringing a sample containing an analyte into contact with a carrier to bind the analyte to the carrier; an elution step of bringing the carrier to which the analyte is bound into contact with an eluate containing a volatile organic solvent to elute the analyte into the eluate; a disposition step of disposing the eluate into which the analyte has been eluted on a measurement plate for mass spectrometry; and a detection step of detecting the analyte by mass spectrometry, in which in the elution step, a use amount of the eluate is determined according to the humidity.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

65.

COMBUSTION GAS ABSORPTION SOLUTION PRODUCTION APPARATUS, AND COMBUSTION ION CHROMATOGRAPH

      
Application Number JP2023018977
Publication Number 2024/034216
Status In Force
Filing Date 2023-05-22
Publication Date 2024-02-15
Owner SHIMADZU CORPORATION (Japan)
Inventor Ikezawa, Yoshio

Abstract

This combustion gas absorption solution production apparatus is provided with: a supply unit; a combustion unit that decomposes a sample by combustion to generate a combustion gas; and an absorption unit that allows the combustion gas generated in the combustion unit to be absorbed into an absorption solution. The supply unit supplies the sample supplied from a sample supply unit to the combustion unit, and also supplies the absorption solution supplied from the absorption solution supply unit to the absorption unit.

IPC Classes  ?

  • G01N 31/12 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods using combustion
  • G01N 1/22 - Devices for withdrawing samples in the gaseous state
  • G01N 30/02 - Column chromatography

66.

QUANTITATIVE DETERMINATION METHOD FOR REACTIVE SULFUR

      
Application Number 18230494
Status Pending
Filing Date 2023-08-04
First Publication Date 2024-02-15
Owner
  • SHIMADZU CORPORATION (Japan)
  • Shimadzu Techno-Research, Inc. (Japan)
Inventor
  • Kunisawa, Akihiro
  • Toyama, Atsuhiko
  • Akaike, Takaaki
  • Ibushi, Tsubasa

Abstract

Provided is a quantitative determination method for sulfur compounds in a target group selected from a plurality of groups, e.g., a group including cysteine and related reactive sulfurs, including the steps of: performing an LC/MS/MS measurement of a standard substance having a known concentration of a base compound, e.g., cysteine, in the target group; acquiring quantitative reference information used for quantitative determination of the base compound and other reactive sulfurs, based on the measurement result, assuming that the signal intensities of sulfur compounds in the same group show a predetermined relationship when their concentrations are equal; performing an LC/MS/MS measurement for each sulfur compound in a specimen, under an analysis condition determined beforehand so that the signal intensities of sulfur compounds in the same group show the predetermined relationship when their concentrations are equal; and determining the quantity of each sulfur compound, using the measurement result and quantitative reference information.

IPC Classes  ?

67.

X-RAY FLUOROSCOPIC IMAGING APPARATUS

      
Application Number 18258261
Status Pending
Filing Date 2021-10-11
First Publication Date 2024-02-15
Owner SHIMADZU CORPORATION (Japan)
Inventor Yamamoto, Takaya

Abstract

An X-ray fluoroscopic imaging apparatus includes an imaging unit, an X-ray image acquisition unit configured to acquire an X-ray image, a target distribution learning identification unit for outputting distribution of a target appearing in an X-ray image using a learning model, an image quality improvement processing unit, and a display unit. The image quality improvement processing unit is configured to switch, using a learning identification result by a target distribution learning identification unit, between a first image processing mode for performing image quality improvement processing on an X-ray image and a second image processing mode for performing image quality improvement processing on the X-ray image without using the learning identification result.

IPC Classes  ?

  • A61B 6/00 - Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
  • G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
  • G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

68.

HEALTH RISK REDUCTION METHOD, HEALTH RISK REDUCTION SYSTEM, AND HEALTH RISK REDUCTION PROGRAM

      
Application Number 18335446
Status Pending
Filing Date 2023-06-15
First Publication Date 2024-02-15
Owner Shimadzu Corporation (Japan)
Inventor Kagami, Daisuke

Abstract

A health risk reduction method includes a step of acquiring physical fitness test data by a physical fitness measurement performed to measure physical fitness of a subject, a step of acquiring cognitive function test data by a cognitive function test of the subject, a step of acquiring exercise content information to be proposed to the subject, based on the physical fitness test data and the cognitive function test data, and a step of outputting the exercise content information to be proposed to the subject.

IPC Classes  ?

  • G16H 20/30 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
  • G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records

69.

MEASUREMENT METHOD

      
Application Number JP2023026962
Publication Number 2024/034371
Status In Force
Filing Date 2023-07-24
Publication Date 2024-02-15
Owner
  • SHIMADZU CORPORATION (Japan)
  • THE UNIVERSITY OF TOKYO (Japan)
Inventor
  • Aoki, Kengo
  • Oda, Ryutaro
  • Ohta, Seiichi
  • Tsuchiya, Hiroki
  • Nakamura, Noriko

Abstract

Labels (2a, 2b) in a first label group and labels (2c, 2d) in a second label group have different labeling properties from one another. Each particle group includes a plurality of particle subgroups (a to d) that differ from each other in particle size. Furthermore, this measurement method comprises: a step for mixing a sample, particles (1a to 1d), and the labels (2a to 2d); a step for specifically binding the labels (2a to 2d) and the labels (2a to 2d) to a biomolecule; a step for separating each of the particles on the basis of the particle size; a step for detecting labeling properties of the labels; and a step for determining the type of biomolecules bound to the particles on the basis of the particle size and the labeling properties.

IPC Classes  ?

  • G01N 33/53 - Immunoassay; Biospecific binding assay; Materials therefor
  • G01N 15/02 - Investigating particle size or size distribution
  • G01N 15/04 - Investigating sedimentation of particle suspensions
  • G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups
  • G01N 33/48 - Biological material, e.g. blood, urine; Haemocytometers
  • G01N 33/483 - Physical analysis of biological material
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • G01N 33/552 - Glass or silica
  • G01N 33/553 - Metal or metal coated

70.

MATRIX SOLUTION, MASS SPECTROMETRY METHOD, STORAGE MEDIUM, AND DETERMINATION METHOD

      
Application Number JP2023028052
Publication Number 2024/034453
Status In Force
Filing Date 2023-08-01
Publication Date 2024-02-15
Owner SHIMADZU CORPORATION (Japan)
Inventor Teramoto, Kanae

Abstract

Provided is a matrix solution used for the mixing with a sample in a matrix assisted laser desorption/ionization mass spectrometry method. The matrix solution is an aqueous solution comprising acetonitrile, ethanol, trifluoroacetic acid and water. The content of acetonitrile is 30 to 40% by volume relative to the mass of the matrix solution. The content of ethanol is 10 to 20% by volume relative to the mass of the matrix solution. The content of trifluoroacetic acid is 1 to 3% by volume relative to the mass of the matrix solution. The matrix solution contains α-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid or sinapic acid in an amount of 5 to 20 mg/ml.

IPC Classes  ?

  • G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
  • G01N 33/483 - Physical analysis of biological material

71.

GAS MEASUREMENT DEVICE

      
Application Number JP2023028260
Publication Number 2024/034487
Status In Force
Filing Date 2023-08-02
Publication Date 2024-02-15
Owner SHIMADZU CORPORATION (Japan)
Inventor Araya, Katsuhiko

Abstract

A gas measurement device (1) includes: a first detection unit (120) for detecting a first component in a sample gas; and a second detection unit (140) for detecting a second component and a third component, respectively, which are components interfering with the first component. The first detection unit includes a first sample cell (122) and a first detector (10A) which are arranged in series on a first optical path (IR1) of light emitted from a first light source (124). The second detection unit (140) includes a second sample cell (142), a second detector (10B) and a third detector (10C), which are arranged in series on a second optical path (IR2) of light emitted from a second light source (144).

IPC Classes  ?

  • G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis

72.

GAS MEASUREMENT DEVICE, AND METHOD FOR DETERMINING CONCENTRATION OF COMPONENT OF INTEREST

      
Application Number JP2023028262
Publication Number 2024/034488
Status In Force
Filing Date 2023-08-02
Publication Date 2024-02-15
Owner SHIMADZU CORPORATION (Japan)
Inventor Araya, Katsuhiko

Abstract

The concentration of each of a plurality of gas components is expressed as a corrected concentration obtained by subtracting, from a pre-correction concentration corresponding to a detected value for said gas component, a measurement error to which the measurement of said gas component is subject due to one or more interfering components affecting said gas component. The measurement error to which the measurement of the gas component is subject is expressed by a linear sum of corrected concentrations of the interfering components affecting said gas component and influence coefficients indicating the degree to which said interfering components influence the measurement of said gas component. According to the relationship between the corrected concentration and the pre-correction concentration for each of the plurality of gas components, the concentration of a component of interest is determined on the basis of the multiple influence coefficients and the respective detected values for said plurality of gas components.

IPC Classes  ?

  • G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis

73.

X-ray imaging device

      
Application Number 29843672
Grant Number D1014759
Status In Force
Filing Date 2022-06-23
First Publication Date 2024-02-13
Grant Date 2024-02-13
Owner SHIMADZU CORPORATION (Japan)
Inventor Takegawa, Ryo

74.

Microscopic Raman Device

      
Application Number 18227296
Status Pending
Filing Date 2023-07-27
First Publication Date 2024-02-08
Owner SHIMADZU CORPORATION (Japan)
Inventor Tao, Tomoyo

Abstract

Provided is a microscopic Raman device including: a first laser light source that generates a first laser light; a second laser light source that generates a second laser light having a wavelength different from a wavelength of the first laser light; a first optical element; a second optical element; a third optical element; a fourth optical element; and a spectrometer. When the first laser light is reflected by the first optical element and passes through the third optical element to irradiate a sample, a first Raman scattered light is generated from the sample. When the second laser light is sequentially reflected by the second optical element, the fourth optical element, and the third optical element to irradiate the sample, a second Raman scattered light is generated from the sample. The first Raman scattered light passes through the third optical element and the first optical element to enter the spectrometer.

IPC Classes  ?

75.

X-RAY IMAGING SYSTEM AND X-RAY IMAGE ANALYSIS METHOD

      
Application Number 18364603
Status Pending
Filing Date 2023-08-03
First Publication Date 2024-02-08
Owner Shimadzu Corporation (Japan)
Inventor
  • Sawada, Ryuji
  • Yoshiyama, Hitomi
  • Tsushima, Hiroaki

Abstract

In an X-ray imaging, first and second images of X-ray images corresponding to different emission angles are generated. In the X-ray imaging system, based on positions of a target part included in an inspection target in the first and second images, and an angle difference between the emission angles of X-rays that are emitted to generate the first and second images, a three-dimensional position of the target part is calculated by using triangulation.

IPC Classes  ?

  • G01N 23/04 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material
  • G01N 23/083 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and measuring the absorption the radiation being X-rays
  • G06T 7/73 - Determining position or orientation of objects or cameras using feature-based methods

76.

X-RAY IMAGING DEVICE AND X-RAY TUBES

      
Application Number JP2023027878
Publication Number 2024/029474
Status In Force
Filing Date 2023-07-28
Publication Date 2024-02-08
Owner SHIMADZU CORPORATION (Japan)
Inventor Tamura, Tomomi

Abstract

This X-ray imaging device (100) comprises: an X-ray tube (1) including a target (30), an electron beam emitting unit (11), and a vacuum container (15); a detector (2); a subject placement unit (3); and an image processing unit (5). The target includes an X-ray generation unit (32) that generates X-rays and a heat dissipation layer (33) provided on the surface (32a) of the X-ray generation unit on the side of the electron beam emitting unit. The thermal conductivity in the plane direction of the heat dissipation layer is greater than the thermal conductivity in the thickness direction of the heat dissipation layer.

IPC Classes  ?

  • H01J 35/08 - Anodes; Anticathodes
  • G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
  • H05G 1/00 - X-ray apparatus involving X-ray tubes; Circuits therefor

77.

PREPARATIVE LIQUID CHROMATOGRAPH

      
Application Number 18221621
Status Pending
Filing Date 2023-07-13
First Publication Date 2024-02-08
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Tamaoki, Soichiro
  • Yamazaki, Tomoyuki
  • Sato, Shohei

Abstract

Provided is a preparative liquid chromatograph capable of coping with a case where actual second delay time changes after start of a fractionation sequence. When a specific component detected as a peak in both a first detector and a second detector is injected during execution of a fractionation sequence, a control device executes maintenance operation of time difference information stored in an information storage area. In the maintenance operation, the control device executes peak determination as to whether or not a difference between first retention time and second retention time falls within a predetermined allowable range. By the above, the control device checks whether or not the second delay time from when a component is detected by the second detector to when the component reaches a fraction collector changes from a previous state.

IPC Classes  ?

78.

RECOVERY SOLUTION GENERATING DEVICE FOR COMBUSTION ION CHROMATOGRAPH

      
Application Number JP2023027319
Publication Number 2024/029415
Status In Force
Filing Date 2023-07-26
Publication Date 2024-02-08
Owner SHIMADZU CORPORATION (Japan)
Inventor Ikezawa Yoshio

Abstract

This recovery solution generating device comprises: a combustion tube (16) for generating a recovery target component by burning a sample; a carrier gas supply unit (23) for supplying a carrier gas to the combustion tube (16) and causing the recovery target component generated in the combustion tube (16) to flow out from an outlet of the combustion tube (16) by means of the carrier gas; an absorption unit (6) including a plurality of absorption tubes (30) each accommodating an absorption liquid for absorbing and recovering the recovery target component, and an absorption tube selection valve (34) for selecting one of the absorption tubes (30) to be fluidly connected to the outlet of the combustion tube (16), from among the plurality of absorption tubes; and a control unit (36) for controlling the operation of the absorption unit (6) such that the recovery target component generated from the sample introduced into the combustion tube (16) is recovered by a prescribed one of the absorption tubes (30).

IPC Classes  ?

  • G01N 30/02 - Column chromatography
  • G01N 30/06 - Preparation
  • G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups

79.

IMAGE PROCESSING METHOD, IMAGE PROCESSING APPARATUS, AND NUCLEAR MEDICAL DIAGNOSTIC APPARATUS

      
Application Number 18221161
Status Pending
Filing Date 2023-07-12
First Publication Date 2024-02-01
Owner SHIMADZU CORPORATION (Japan)
Inventor Yamakawa, Yoshiyuki

Abstract

An image processing method includes a reconstruction step of reconstructing a radiographic image of a subject by performing reconstruction processing on radiological data of the subject, a count number calculation step of calculating a count number in a subject area in the radiographic image, a standard deviation calculation step of calculating a noise standard deviation in the radiographic image from a relation between the count number in each of a plurality of pre-acquired function calculation radiographic images and the noise standard deviation, by substituting the count number in the subject area into a pre-acquired basic noise deviation function a function in which a value of the count number and a value of the noise standard deviation correspond to each other, and a noise reduction processing step of performing NLM filter processing on the radiographic image using the noise standard deviation calculated in the standard deviation calculation step.

IPC Classes  ?

  • G06T 11/00 - 2D [Two Dimensional] image generation

80.

Mass Spectrometer and Mass Spectrometry Method

      
Application Number 18265339
Status Pending
Filing Date 2021-12-23
First Publication Date 2024-02-01
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Mitsui, Kazutaka
  • Takahashi, Hidenori

Abstract

Provided is a mass spectrometer including: a reaction chamber (132) into which a precursor ion is introduced; a radical generation part (54) configured to generate a known radical; a radical supply part (5) configured to react the precursor ion with the radical to generate fragment ions and an adduct ion; a measurement control part (63) configured to measure ions including the precursor ion, the fragment ions, and the adduct ion to obtain a mass spectrum; and an accurate mass estimation part (64) configured to specify a peak of the adduct ion by searching a predetermined mass range centered on a mass value obtained by adding a mass of an atom or molecule derived from the radical to a mass obtained from a peak of the precursor ion, and estimate an accurate mass of the precursor ion by subtracting an accurate mass of the atom or molecule from an accurate mass of the peak.

IPC Classes  ?

  • H01J 49/00 - Particle spectrometers or separator tubes
  • G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode

81.

MONITORING DEVICE AND MONITORING SYSTEM

      
Application Number 18357150
Status Pending
Filing Date 2023-07-23
First Publication Date 2024-02-01
Owner SHIMADZU CORPORATION (Japan)
Inventor Matsuura, Tohru

Abstract

A monitoring device is a monitoring device of a material testing machine including a display having a marker on a display panel. The monitoring device includes: an acquisition unit that acquires a photographed image of a camera that photographs the display panel; a first generation unit that generates a first processed image obtained by gray-scaling the photographed image; a second generation unit that generates a second processed image obtained by performing blur processing on the first processed image; a third generation unit that generates a third processed image obtained by binarizing the first processed image based on the second processed image; and a first detection unit that detects the marker from the third processed image.

IPC Classes  ?

  • G06T 7/00 - Image analysis
  • G06T 7/70 - Determining position or orientation of objects or cameras

82.

SAMPLE PLATE HOLDER FOR MASS SPECTROMETRY DEVICE

      
Application Number JP2023016677
Publication Number 2024/024194
Status In Force
Filing Date 2023-04-27
Publication Date 2024-02-01
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Harada, Takahiro
  • Terashima, Kenta
  • Kudo, Tomoya

Abstract

A sample plate holder (6) for a mass spectrometry device comprises: urging members (631 to 633) for pushing one surface of a sample plate toward another surface thereof at three locations that are not positioned on a straight line; and abutting members (612 to 614) which abut said other surface of the sample plate (5) in positions corresponding to the three locations as seen in a plan view. The sample plate holder (6) can suitably be employed in a mass spectrometry device (1) comprising: a laser light emitting unit (13) for emitting laser light onto a sample placed on the sample plate; and a mass spectrometry unit (30) for performing mass spectrometry of ions generated from the sample (S) as a result of the emission of the laser light.

IPC Classes  ?

  • G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
  • H01J 49/00 - Particle spectrometers or separator tubes
  • H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
  • H01J 49/16 - Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
  • H01J 49/40 - Time-of-flight spectrometers

83.

AUTOMATIC ANALYSIS SYSTEM

      
Application Number JP2023018822
Publication Number 2024/024229
Status In Force
Filing Date 2023-05-19
Publication Date 2024-02-01
Owner SHIMADZU CORPORATION (Japan)
Inventor Sugiyama, Kiyohiro

Abstract

This automatic analysis system comprises: an analysis unit (10) capable of selectively executing a general sample analysis or an accuracy management analysis; a display input unit (30); a time setting storage unit (40) in which setting relating to the execution time for the accuracy management analysis is stored; a display control unit (50) that displays a postponement instruction key on the display input unit at a prescribed timing earlier than the execution time determined on the basis of the setting stored in the time setting storage unit; and a postponement control unit (60) that postpones the execution time on the basis of prescribed operation having been performed on the postponement instruction key. Accordingly, it is possible to perform appropriate analysis management according to a situation in an automatic analysis device that performs an accuracy management analysis at the preset time.

IPC Classes  ?

  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor

84.

ANALYSIS SYSTEM AND DATA PROCESSING DEVICE

      
Application Number JP2023019064
Publication Number 2024/024237
Status In Force
Filing Date 2023-05-23
Publication Date 2024-02-01
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Sudo, Tomokazu
  • Sugiyama, Kiyohiro

Abstract

The present invention is an analysis system 1 comprising: an analysis device 10 for performing analyses by mixing reagents in reagent containers 114 held by a reagent-holding unit 111 with test specimens in specimen containers held by a specimen-holding unit 121; and a data processing device 30 having a temperature information collection part 310 for collecting temperature information pertaining to the reagent-holding unit via a data communication network 20. The data processing device comprises: a display unit 33 for displaying a screen showing the temperature information collected by the temperature information collection part; a temperature determination part 313 for determining whether or not the temperature of the reagent-holding unit has deviated from a predetermined temperature range on the basis of the temperature information; and a display control part 314 for causing the display screen showing the temperature information to pop up as it is determined by the temperature determination part that the temperature of the reagent-holding unit has deviated from the predetermined temperature range.

IPC Classes  ?

  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor

85.

UNDERWATER OPTICAL WIRELESS COMMUNICATION SYSTEM

      
Application Number JP2023021141
Publication Number 2024/024289
Status In Force
Filing Date 2023-06-07
Publication Date 2024-02-01
Owner SHIMADZU CORPORATION (Japan)
Inventor Ebara, Yuki

Abstract

This underwater optical wireless communication system (100) comprises: a first communication device (2) that rotates underwater together with a rotating body (1); and a second communication device (3) that wirelessly communicates with the first communication device in a direction intersecting a rotation axis (60) of the rotating body, wherein the first communication device has a first light emitting unit (20) that emits first light (50), and a first information conversion unit (21) that converts, to the first light, state information input from a state information detection unit (4) which detects state information (40) serving as information pertaining to the state of the rotating body, and the second communication device has a second light receiving unit (30) that receives the first light.

IPC Classes  ?

  • H04B 10/80 - Optical aspects relating to the use of optical transmission for specific applications, not provided for in groups , e.g. optical power feeding or optical transmission through water
  • G08C 15/06 - Arrangements characterised by the use of multiplexing for the transmission of a plurality of signals over a common path successively, i.e. using time division

86.

living laboratory

      
Application Number 018978773
Status Pending
Filing Date 2024-01-26
Owner Shimadzu Corporation (Japan)
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Measuring instruments; testing instruments; liquid and gas chromatography apparatuses; liquid and gas chromatograph-mass spectrometry apparatuses; energy-dispersive X-ray spectrometers; spectrophotometers; spectrofluorometers; fourier-transform infrared spectrometers; total organic carbon analyzers; balances; thermal analyzers; particle size analyzers; atomic absorption spectrophotometers for laboratory use; cell culture analysis apparatus; pretreatment device of culture media samples for cell culture analysis and testing machines; Weighing equipment; electronic balances; Computer programs for controlling and managing goods and data obtained from scientific analysis; computer software; Downloadable software. Computer software design; computer software programming services; maintenance of computer software; Testing cosmetics; Testing food(stuffs); Inspection of pharmaceuticals; Inspection of cosmetics; Inspection of food(stuffs); Testing pharmaceuticals; research of pharmaceuticals; research of cosmetics; research of food; Chemical research; Chemistry services; Chemical analysis; Bacteriological research; Biological research; Clinical trials; Testing or research on prevention of pollution; Material testing; Water analysis; Testing, inspection or research on agriculture, livestock breeding or fisheries; Testing or research on machines, apparatus and instruments; Providing computer programs on data networks.

87.

METHOD OF ASSISTING BREAST CANCER DIAGNOSIS AND TEST KIT FOR BREAST CANCER

      
Application Number 18265547
Status Pending
Filing Date 2021-12-06
First Publication Date 2024-01-25
Owner
  • NATIONAL CANCER CENTER (Japan)
  • SHIMADZU CORPORATION (Japan)
  • DAI NIPPON TORYO CO., LTD. (Japan)
Inventor
  • Tamura, Kenji
  • Sudo, Kazuki
  • Matsuda, Takahisa
  • Yamaji, Taiki
  • Okamoto, Koji
  • Watanabe, Makoto
  • Fujimoto, Hirotaka
  • Sato, Taka-Aki
  • Miyazawa, Yuta

Abstract

Provided is a method of assisting breast cancer diagnosis, comprising: a measuring step for measuring an amount of laminin 5 or laminin β3 in a specimen; and an information-providing step for providing information for breast cancer diagnosis based on the amount of laminin 5 or laminin β3 thus measured. Provided is a test kit for breast cancer comprising an anti-laminin 5 antibody or an anti-laminin β3 antibody.

IPC Classes  ?

  • G01N 33/574 - Immunoassay; Biospecific binding assay; Materials therefor for cancer
  • G01N 33/543 - Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
  • C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans

88.

BLOOD COLLECTION INSTRUMENT AND BLOOD COLLECTION PLATE

      
Application Number 18024382
Status Pending
Filing Date 2021-09-02
First Publication Date 2024-01-25
Owner
  • SHIMADZU CORPORATION (Japan)
  • NIPRO CORPORATION (Japan)
  • HUNDRED CO., LTD. (Japan)
Inventor
  • Takeuchi, Ippei
  • Nakagami, Hiroyuki
  • Kudo, Tatsuya
  • Eshima, Takashi
  • Kayamoto, Naoyuki
  • Murakami, Makoto

Abstract

A novel blood collection instrument with which it is possible to prevent blood from coming into contact with air during collection of blood, and a blood collection plate that is suitably used therefor. A blood collection instrument including: a blood holding member having a structure in which a plurality of plate-shaped members, are overlapped with each other and including a collected blood holding passage formed between overlapped surfaces of the plate-shaped members; a connection part provided at an inflow port of the collected blood holding passage in the blood holding member; and a puncture member including a puncturing hollow needle while being connected to the connection part. An inner hole of the hollow needle of the puncture member is allowed to communicate with the collected blood holding passage in the blood holding member.

IPC Classes  ?

  • A61B 5/15 - Devices for taking samples of blood

89.

IMAGING ANALYSIS METHOD AND DEVICE USING ION MOBILITY MASS SPECTROMETRY

      
Application Number JP2022028407
Publication Number 2024/018607
Status In Force
Filing Date 2022-07-21
Publication Date 2024-01-25
Owner SHIMADZU CORPORATION (Japan)
Inventor Yamaguchi, Shinichi

Abstract

An embodiment of an imaging analysis device according to the present invention comprises: a measurement unit that acquires analysis result data by performing ion mobility mass spectrometry for each micro-region in a predetermined measurement region of a sample; a correlation investigation unit (22, 23) that investigates a correlation between m/z and ion mobility in the analysis result data acquired by the measurement unit on the basis of said data; and a data reduction unit (24, 25) that reduces the amount of the analysis result data by limiting an ion mobility range according to m/z or limiting an m/z range according to ion mobility, on the basis of the correlation result acquired by the correlation investigation unit.

IPC Classes  ?

  • G01N 27/623 - Ion mobility spectrometry combined with mass spectrometry

90.

AUTOMATED ANALYZER

      
Application Number 18018293
Status Pending
Filing Date 2021-05-18
First Publication Date 2024-01-25
Owner Shimadzu Corporation (Japan)
Inventor Okada, Kohji

Abstract

An automated analyzer includes: a measurement device; at least one sample tray on which a plurality of sample containers is placed; a conveyance device configured to select one of the plurality of sample containers placed on the sample tray, convey the selected sample container to the measurement device, and return the sample container to an original sample tray on which the sample container was originally placed after measurement by the measurement device; a control device for controlling an operation of the conveyance device; and a retreat portion provided at a position different from positions where the measurement device and the sample tray are provided, the retreat portion being configured to temporarily place the sample container. The control device causes the sample container to retreat to the retreat portion in a case where the sample container cannot be returned from the measurement device to the sample tray.

IPC Classes  ?

  • G01N 23/2204 - Specimen supports therefor; Sample conveying means therefor
  • G01N 35/04 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations - Details of the conveyor system
  • G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence

91.

MASS SPECTROMETRY METHOD AND MASS SPECTROMETER

      
Application Number 18028931
Status Pending
Filing Date 2021-07-30
First Publication Date 2024-01-25
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Takahashi, Hidenori
  • Yamaguchi, Shinichi

Abstract

A mass spectrometer including: a reaction chamber into which a precursor ion derived from a sample molecule is introduced; a collision gas supply part configured to supply collision gas to the reaction chamber; a radical supply part configured to supply hydrogen radicals, oxygen radicals, nitrogen radicals, or hydroxyl radicals to the reaction chamber; a dissociation operation control part configured to control operations of the collision gas supply part and the radical supply part to generate the product ions by collision-induced dissociation and radical attachment dissociation of the precursor ion inside the reaction chamber, an ion detection part configured to mass-separate and detect ions ejected from the reaction chamber, and a spectrum data generation part configured to generate spectrum data based on a detection result by the ion detection part.

IPC Classes  ?

  • H01J 49/00 - Particle spectrometers or separator tubes

92.

SCANNING PROBE MICROSCOPE AND CONTROL METHOD

      
Application Number JP2023021095
Publication Number 2024/014186
Status In Force
Filing Date 2023-06-07
Publication Date 2024-01-18
Owner SHIMADZU CORPORATION (Japan)
Inventor Fujino, Keita

Abstract

A detecting mechanism (110) acquires first information indicating the position of a cantilever in the Z-axis direction and second information indicating the position of a sample S in the Z-axis direction or the position of a sample stand (14) in the Z-axis direction. An approach processing part (104) determines a speed reduction position on the basis of the first information and the second information. The approach processing part (104) controls a displacement mechanism so that an approach speed changes from high speed to low speed at the speed reduction position.

IPC Classes  ?

  • G01Q 10/02 - Coarse scanning or positioning
  • G01Q 60/24 - AFM [Atomic Force Microscopy] or apparatus therefor, e.g. AFM probes

93.

IMAGE PROCESSING METHOD, IMAGE PROCESSING DEVICE, SCANNING PROBE MICROSCOPE, AND PROGRAM

      
Application Number JP2023021094
Publication Number 2024/014185
Status In Force
Filing Date 2023-06-07
Publication Date 2024-01-18
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Hirade, Masato
  • Yamasaki, Kenji

Abstract

Provided is a technology for identifying the type of a correction according to the state of the surface of a sample, an image of which has been generated on the basis of the measurement using a scanning probe microscope An image processing method according to the present invention comprises a step (SA1) for generating a corrected image by performing a first correction on a target image. The first correction includes extracting, from the target image, a plurality of pixels on a straight line along a prescribed direction on a prescribed plane and correcting the height of the target image on the basis of the luminance of each of the pixels extracted. The image processing method further comprises: a step (SA3) for generating a histogram of the pixel values in the corrected image; and a step (SA4) for using the histogram to determine whether or not a second correction, which is different from the first correction, is necessary on the target image.

IPC Classes  ?

  • G01Q 30/06 - Display or data processing devices for error compensation
  • G01Q 60/10 - STM [Scanning Tunnelling Microscopy] or apparatus therefor, e.g. STM probes
  • G01Q 60/24 - AFM [Atomic Force Microscopy] or apparatus therefor, e.g. AFM probes

94.

INSPECTION APPARATUS

      
Application Number 18021865
Status Pending
Filing Date 2021-05-06
First Publication Date 2024-01-11
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Nieda, Yoshiaki
  • Masuda, Yuichi
  • Yahata, Masahito
  • Kataoka, Tatsuya

Abstract

An ultraviolet ray emitter includes an inner tube, an outer tube arranged around the inner tube, the outer tube defining between the outer tube and the inner tube, a discharge space where discharge gas is sealed, a pair of electrodes that causes discharge in the discharge space, and an auxiliary light source that assists excitation of discharge gas by emitting light to discharge gas from the outside of the outer tube. The outer tube is less likely to allow passage therethrough of ultraviolet light generated by excitation of discharge gas than the inner tube but allows passage therethrough of light having a wavelength emitted from the auxiliary light source.

IPC Classes  ?

  • G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups

95.

SAMPLING DEVICE

      
Application Number 18203003
Status Pending
Filing Date 2023-05-29
First Publication Date 2024-01-11
Owner SHIMADZU CORPORATION (Japan)
Inventor Obe, Tatsuya

Abstract

A sampling needle (21) is inserted into a sample container (12) by a needle-driving mechanism (23) to collect a sample liquid from the sample container. A depth information acquirer (52) acquires insertion depth information, i.e., a piece of information concerning an insertion depth of the sampling needle into the sample container. A needle-rinsing length setter (54) sets a needle-rinsing length which is an insertion length of the sampling needle into a rinse storage tank (30) having an open top, based on the insertion depth information. A controller (51) controls the needle-driving mechanism so that a portion of the sampling needle extending from the tip of the sampling needle over the needle-rinsing length is inserted into the rinse storage tank. The needle-rinsing length setter is configured to set a shorter needle-rinsing length for a smaller insertion depth of the sampling needle into the sample container, to shorten the needle-cleaning time.

IPC Classes  ?

96.

ANALYSIS SYSTEM AND ANALYSIS METHOD

      
Application Number 18213479
Status Pending
Filing Date 2023-06-23
First Publication Date 2024-01-11
Owner SHIMADZU CORPORATION (Japan)
Inventor Hinooka, Motomu

Abstract

An analysis system includes a gripper arm for conveying a sample container, and a controller for controlling the gripper arm. The gripper arm includes a first gripper and a second gripper for holding the sample container by pinching the sample container, a drive mechanism that changes a size of a gripping space between the first gripper and the second gripper, and a photoelectric sensor for emitting light to the gripping space to detect the light from the gripping space. The controller determines the presence or absence of the sample container in the gripping space based on the presence or absence of a detection signal of the photoelectric sensor.

IPC Classes  ?

  • G01N 35/04 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations - Details of the conveyor system
  • G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor

97.

CHROMATOGRAPHY QUALITY CONTROL DEVICE AND CHROMATOGRAPHY QUALITY CONTROL METHOD

      
Application Number 18220653
Status Pending
Filing Date 2023-07-11
First Publication Date 2024-01-11
Owner SHIMADZU CORPORATION (Japan)
Inventor Noda, Akira

Abstract

A chromatography quality control device includes a measurement data acquirer that acquires measurement data obtained as a result of measurement in a chromatograph and stores the measurement data in a storage device, a chromatogram factorizer that retrieves the measurement data from the storage device, dimensionally compresses a chromatogram obtained from the measurement data by factorization and stores component data, the component data obtained by the factorization, in the storage device, and a component data outputter that retrieves the component data from the storage device and outputs the component data to a display device.

IPC Classes  ?

  • G01N 30/06 - Preparation
  • G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups

98.

CAP MOUNTING/REMOVAL DEVICE, PREPROCESSING DEVICE, AND METHOD FOR ATTACHING CAP

      
Application Number JP2023023031
Publication Number 2024/009778
Status In Force
Filing Date 2023-06-21
Publication Date 2024-01-11
Owner SHIMADZU CORPORATION (Japan)
Inventor
  • Tsukahara, Mio
  • Shibabuki, Tadanobu

Abstract

In the present invention, when a cap is being attached to a container, an operation unit grips the cap while contacting the top surface of the cap, on which a threaded portion is formed, and brings the gripped cap into contact with the container. A buffer unit absorbs pressing force applied from the cap to the operation unit. A control unit executes, in order: a control for causing a rotation-driving unit to rotate in a first direction, thereby fastening the cap gripped by the operation unit onto the container; a control for causing the rotation-driving unit to rotate in a second direction, thereby loosening the cap gripped by the operation unit from the container; and a control in which the rotation-driving unit is rotated in the first direction, as a result of which the cap gripped by the operation unit is fastened onto the container.

IPC Classes  ?

  • B25J 9/00 - Programme-controlled manipulators
  • G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
  • B67B 1/06 - Closing bottles, jars, or similar containers by applying stoppers by inserting and rotating screw stoppers
  • B67B 3/20 - Closing bottles, jars, or similar containers by applying caps by applying and rotating preformed threaded caps
  • B67B 7/18 - Hand- or power-operated devices for opening closed containers for removing threaded caps
  • B25J 15/08 - Gripping heads having finger members

99.

AUTOMATIC SAMPLE INJECTION DEVICE AND METHOD OF CONTROLLING AUTOMATIC SAMPLE INJECTION DEVICE

      
Application Number 18039376
Status Pending
Filing Date 2020-12-03
First Publication Date 2024-01-04
Owner SHIMADZU CORPORATION (Japan)
Inventor Nozawa, Tomonori

Abstract

A controller (14) slows down and stops a turret (12) when a sensor 33 detects a first detection target portion (31) in a detection area (34). The controller (14) acquires information corresponding to the movement distance (D1) of the first detection target portion (31) from the start of slowdown of the turret (12) to the stop of the turret (12). The controller (14) moves the first detection target portion (31) in a second direction (A2) by the movement distance (D1). The controller (14) moves the first detection target portion (31) in the second direction (A2) to a second position (P6) outside the detection area (34). The controller (14) moves the turret (12) to move the first detection target portion (31) in a first direction (A1) from the second position (P6) to an origin (P0).

IPC Classes  ?

  • G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

100.

MEASUREMENT VALUE PROCESSING METHOD AND MEASUREMENT VALUE PROCESSING SYSTEM

      
Application Number JP2023009054
Publication Number 2024/004281
Status In Force
Filing Date 2023-03-09
Publication Date 2024-01-04
Owner SHIMADZU CORPORATION (Japan)
Inventor Inoue Taimu

Abstract

The present invention comprises: a reference value searching step for searching for a reference value R from among N measurement values; a selection step for selecting M measurement values by excluding, from the estimation target, N-M measurement values, as outliers, in descending order of deviation from the reference value R, among the N measurement values, on the basis of the reference value R searched for in the reference value searching step; and an estimation value calculation step for setting an average value of the M measurement values selected in the selection step as an estimation value of a true value. The reference value searching step includes a loop repeating from a state n=N until n=1, a process for determining the median or average value of the n measurement values, excluding one measurement value with the largest deviation from the median value or the average value among the n measurement values, and setting n-1 measurement values as candidates for the reference value R, and after the loop ends, one last remaining measurement value as the candidate is set as the reference value R.

IPC Classes  ?

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