A treatment device (1) is provided with: a vessel (50) for containing a sample; pipes (11-13) for introducing, into the vessel, a treatment liquid for decomposing an impurity contained in the sample; a port (64) that discharges, from the vessel containing the sample, a liquid contained in the sample as waste liquid; a pump (33) connected to the port; and a control device (500) for controlling the pump. The control device controls the pump so as to enable a predetermined amount or more of the waste liquid to be discharged from the port.
Provided is a diagnosis support system that acquires one or more items of patient information associated with a patient (steps S30, S40), and inputs the one or more items into an estimation model and acquires, from a plurality of diseases, a candidate for a disease that the patient may have (step S50). The diagnosis support system then acquires additional required information to be additionally acquired from the patient on the basis of the candidate for the disease (step S70). The diagnosis support system then presents the additional required information (step S90).
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
3.
METHOD FOR FILLING HEAT TRANSPORT DEVICE WITH REFRIGERANT AND REFRIGERANT FILLING CONTROL DEVICE FOR HEAT TRANSPORT DEVICE
This method for filling a heat transport device (110) with a refrigerant comprises: a pre-filling step (step 902) for filling a refrigerant flow path (10) of a heat transport device (110) with an inactive gas such that the pressure inside the refrigerant flow path (10) of the heat transport device (110) reaches a prescribed pressure; and a main filling step (step 904) for filling the refrigerant flow path (10) of the heat transport device (110) with a refrigerant to a prescribed quantity necessary for operating the heat transport device (110), after the pre-filling step (step 902).
F25B 45/00 - Arrangements for charging or discharging refrigerant
F25B 1/00 - Compression machines, plants or systems with non-reversible cycle
F28D 15/02 - Heat-exchange apparatus with the intermediate heat-transfer medium in closed tubes passing into or through the conduit walls in which the medium condenses and evaporates, e.g. heat-pipes
A computer according to an embodiment of this flow path state output device is connected to a liquid chromatograph and obtains the result of analysis processing performed by the liquid chromatograph. The computer comprises a feature amount acquisition unit and a state output unit. The feature amount acquisition unit measures a sample containing a known component by means of an analysis device, and obtains a feature amount from the measurement result. The state output unit outputs the flow path state of the liquid chromatograph to a display on the basis of the feature amount.
A processing device (1) comprises: a container (50) that accommodates a specimen; a control device (500) that extracts a target substance from the specimen accommodated in the container; and an input device (505) that receives input from a user. The control device performs a refresh process in which a first processing liquid for processing a contaminant included in the specimen is introduced into the container in which the specimen is accommodated, and after the first processing liquid has been introduced, on the basis of an input to the input device, a second processing liquid for re-processing the contaminant included in the specimen is introduced into the container.
This recovery implement (100) recovers subject material contained in a discharged liquid that is discharged from each of a plurality of treatment devices (1A, 1B, 1C) for treating samples. The recovery implement comprises: a plurality of filtration units (110A, 110B, 110C) that are provided corresponding to the plurality of treatment devices, the filtration units filtering the discharged liquid that is discharged from the corresponding treatment devices and extracting the subject material contained in the discharged liquid; a holder (101) that integrally accommodates the plurality of filtration units; and a discharge unit (102) that discharges a waste liquid that has passed through each of the plurality of filtration units. The holder can be detached from the discharge unit together with the plurality of filtration units in which the subject material resides.
B01D 29/90 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups ; Filtering elements therefor having feed or discharge devices for feeding
B01D 29/01 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups ; Filtering elements therefor with flat filtering elements
G01N 1/04 - Devices for withdrawing samples in the solid state, e.g. by cutting
7.
METHOD AND DEVICE FOR SUGGESTING POSITIONING OF ELECTROMAGNETIC SENSORS, AND CURRENT SOURCE LOCATION ESTIMATION METHOD
This method for suggesting the positioning of electromagnetic sensors involves suggesting the positioning of a plurality of electromagnetic sensors positioned on the surface of a living body around a target region inside a subject, using a forward model for estimating electromagnetic fields produced at the positions of the plurality of electromagnetic sensors by biological activity inside the subject, the method including: a step for setting calculation conditions including the position of the target region and the positions at which the plurality of electromagnetic sensors can be positioned; a step for calculating, on the basis of the calculation conditions that have been set, suggested positioning for all or some of the plurality of electromagnetic sensors, which are for estimating the position of a current source inside the subject; and a step for outputting the suggested positioning.
An analysis system (1) comprises an analysis device (100) that analyzes samples. At least one of the constituent elements of the analysis device (100) is a temperature adjustment constituent element (106; 108) that includes a temperature adjustment element (112; 116) and a temperature sensor (112; 116). The temperature adjustment constituent element (106; 108) must perform temperature control by using the temperature adjustment element (112, 116) and the temperature sensor (112, 116) and stabilize the temperature at a set target temperature at the time of starting the analysis. The analysis device (100) enters an analysis-enabled state in which analysis can be started when the temperatures of all the temperature adjustment constituent elements (106; 108) stabilize at the temperature set for each. The analysis system (1) comprises: a time measurement unit (202) that is configured to measure, as stabilization times, the time required from the start of the temperature control until output of the temperature sensor (112; 116) stabilizes, every time the temperature control is executed; a data accumulation unit (204) that is configured to store and accumulate the stabilization times, which are measured by the time measurement unit (202) each time the temperature control is executed, in association with conditions that affect the stabilization times when the temperature control is executed; and a time prediction unit (206) that is configured to calculate a predicted value of the time required for the analysis device (100) to enter the analysis-enabled state, by using a large number of compatible stabilization times, from among the stabilization times accumulated by the data accumulation unit (204), in which the associated conditions are compatible with the conditions at the time of the setting, when the settings for the analysis are made.
This X-ray phase imaging device (100) comprises: an X-ray light source (10), an X-ray detector (11), a plurality of lattices; a rotary mechanism (15) which rotates a subject (90) including fibers (91a) and the plurality of lattices relative to each other; an image processing unit (2a) which generates a plurality of X-ray phase contrast images (40) for each of the orientations of the subject with respect to the plurality of lattices; and a control unit (2b) which acquires orientation information (30) pertaining to the orientations of fibers included in the subject on the basis of the plurality of X-ray phase contrast images, and acquires a feature amount (31) pertaining to the mechanical strength of the subject.
According to the present invention, a management device optimizes a work system. More specifically, this management device: sets a control parameter set that is made up of one or more parameters for controlling actions of the work system (step S10); controls the actions of the work system on the basis of the control parameter set (step S12); acquires an observation value relating to the work system in relation to execution of the actions based on the control parameter set (step S14); calculates a posterior distribution of a model function in which one or more parameters are variables by using the control parameter set and the observation value (step S20); and updates an optimization function for identifying an optimal parameter set as the control parameter set, using calculation results of the posterior distribution (step S24).
Provided is a management method for a test schedule that includes a first step and a second step. The time slots for the first step include time slots for which work on the part of a worker is not required, and the time slots for the second step include time slots for which work on the part of a worker is required. When the second step is arranged in a portion of the first step in a test schedule, the second step is arranged in the test schedule such that time slots in the second step for which work on the part of a worker is required overlap only time slots in the first step for which work on the part of a worker is not required.
SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
Inventor
Andrzejewski, Roch
Giles, Roger
Abstract
EDD TPNTPRREDD NTPRR, is compared to a pre-set target ratio value and, if the comparison reveals a difference therebetween, an adjusted value of the dispersion electric field sufficient reduce the difference is applied across the analytical gap.
SHIMADZU RESEARCH LABORATORY (EUROPE) LTD (United Kingdom)
Inventor
Andrzejewski, Roch
Giles, Roger
Entwistle, Andrew
Abstract
A method of analyzing ions comprising generating ions from a sample in an ion source, delivering them into a vacuum region of a vacuum enclosure comprising an ion mobility analyser having an ion drift region formed between opposing electrodes defining an analytical gap. The ions emerge from the ion inlet as a supersonic jet of a buffer gas within which the ions are entrained to enter the drift region and, e.g., priorto mass spectral analysis of the ions in a downstream vacuum region, conducting differential ion mobility analysis of the ions in the first vacuum region. Priorto conducting differential ion mobility analysis (e.g., and mass spectral analysis) according of the ion, the method comprises a) changing a rate of flow of gas into or out of the vacuum region; b) measuring a gas pressure in the vacuum region and repeating steps a) and b) until a target gas pressure value is achieved; c) measuring a velocity of gas flow along the drift region and repeating steps a) to c) until the measured gas velocity value has achieved a pre-set target gas velocity value and subsequently conducting said differential ion mobility analysis and said mass spectral analysis according to said target gas pressure value and said target gas velocity value.
The present invention is capable of setting a debinding recipe with low power consumption and in a short period of time, and minimizes time consumption and energy loss in an actual debinding treatment performed according to the set recipe. The present invention performs: a data accumulation step for associating existing treatment target analysis data that is obtained by using a differential thermal measurement device, a thermogravimetry device, and/or a thermomechanical analysis device to analyze part of an existing treatment target with debinding result data that indicates the result of debinding the existing treatment target in a debinding furnace, and for accumulating the data in a memory; an analysis step for analyzing, on the basis of the existing treatment target analysis data and the debinding result data which are accumulated in a data accumulation unit, new treatment target analysis data that is obtained by using the differential thermal measurement device, the thermogravimetry device, and/or the thermomechanical analysis device 300 to analyze part of a new treatment target; and a recipe setting step for setting a debinding recipe for the new treatment target on the basis of the analysis result in the analysis step.
B28B 11/00 - Apparatus or processes for treating or working the shaped articles
G01N 25/20 - Investigating or analysing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
15.
METHOD FOR CONTROLLING MOBILE OBJECT, TRANSPORT DEVICE, AND WORK SYSTEM
A management device (100) performs, as a method for controlling a mobile object: a step for generating a machine learning model for generating an operation plan for a mobile object for transporting an object, on the basis of the position of a first feature portion in a simulation space; a step for identifying the position of a second feature portion in the real space; a step for acquiring the relationship between the position of the second feature portion in the real space and a position in the real space corresponding to the position of the first feature portion in the simulation space; a step for applying the position of the second feature portion in the real space and the relationship to the machine learning model, to thereby generate an operation plan for the mobile object; and a step for controlling the operation of the mobile object in accordance with the generated operation plan.
This control method uses an image captured by an image capturing unit (234) to control transport of an object to a target position by using a first moving body (232). The control method comprises: a step for performing proximity control for causing the image capturing unit (234) to be in relative proximity to a characteristic part indicating a reference position different from the target position; a step for causing the image capturing unit (234), which has been put in relative proximity to the characteristic part by the proximity control, to acquire a first image obtained by photographing the characteristic part; and a step for causing the first moving body (232) to transport the object to the target position on the basis of the first image.
The present invention comprises a rotatable C-arm 17 that supports and causes an X-ray tube 13 and an X-ray detector 15 to face each other, an image generating unit 43 that uses a detected signal of the x-ray detector 15 to generate an X-ray image L, and an image display device 11 that displays the X-ray image L. The image display device 11 comprises: an image display unit 49 capable of displaying information display images D in parallel in a matrix shape; an input unit 51 for inputting an instruction for changing the position where image information K is displayed in the information display images D so that at least two X-ray images L are displayed adjacent to each other among the information display images D; and an image display control unit 57 that controls the image display unit 49 so that the X-ray images L are displaced adjacent to each other, on the basis of the content of the instruction.
Provided is a maintenance system wherein a management device manages a database, which stores solution information associated with the state of a medical device, and updates the database. The management device receives state information indicating the state of the medical device from the medical device, which is connected to a network of an organization, via a network outside of the organization. The management device determines solution information corresponding to the state of the medical device on the basis of the state information and the database and transmits the determined solution information to a terminal device having a display unit via the network outside of the organization.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
19.
X-RAY PHASE IMAGING SYSTEM AND X-RAY PHASE IMAGING METHOD
This X-ray phase imaging system (100) comprises: an imaging system (6) including an X-ray source (1), an X-ray detector (2), and a plurality of lattices; a first rotation mechanism (7) which relatively rotates a subject (90) and the imaging system; an image processing unit (81) which generates a three-dimensional dark field-of-view image (43); a filter processing unit (82) which performs a filter process for extracting linear portions (44) included in the subject at a plurality of angles; and a linear portion image generation unit (83) which generates a linear portion image (45) on the basis of the plurality of linear portions corresponding to a fiber (90b).
This X-ray imaging device (100) comprises a first arm (1), a second arm (2), an imaging angle setting unit (4) for setting the respective target imaging angles of a first X-ray source (1a) and a second X-ray source (2a), and a display unit (3). The display unit (3) displays a disposition screen (8) indicating the disposition corresponding to the positions of both the first X-ray source (1a) and the second X-ray source (2a) at the target imaging angles with respect to the position of an actual subject (101). The imaging angle setting unit (4) and the display unit (3) are provided in the same disposition region (103) of an X-ray imaging device body (100a).
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
Teramoto, Kanae
Sekiguchi, Yuji
Abstract
Provided is a mass-spectrometry pretreatment method for a sample containing cells, the method including: a step for bringing the cells into contact with a first acidic solution containing an organic acid; and a step for extracting cytoplasmic components of the cells by heating the cells and the first acidic solution in the state in which said materials are in contact with each other.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
This combustion gas absorption solution production apparatus is provided with: a supply unit; a combustion unit that decomposes a sample by combustion to generate a combustion gas; and an absorption unit that allows the combustion gas generated in the combustion unit to be absorbed into an absorption solution. The supply unit supplies the sample supplied from a sample supply unit to the combustion unit, and also supplies the absorption solution supplied from the absorption solution supply unit to the absorption unit.
G01N 31/12 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods using combustion
G01N 1/22 - Devices for withdrawing samples in the gaseous state
Labels (2a, 2b) in a first label group and labels (2c, 2d) in a second label group have different labeling properties from one another. Each particle group includes a plurality of particle subgroups (a to d) that differ from each other in particle size. Furthermore, this measurement method comprises: a step for mixing a sample, particles (1a to 1d), and the labels (2a to 2d); a step for specifically binding the labels (2a to 2d) and the labels (2a to 2d) to a biomolecule; a step for separating each of the particles on the basis of the particle size; a step for detecting labeling properties of the labels; and a step for determining the type of biomolecules bound to the particles on the basis of the particle size and the labeling properties.
Provided is a matrix solution used for the mixing with a sample in a matrix assisted laser desorption/ionization mass spectrometry method. The matrix solution is an aqueous solution comprising acetonitrile, ethanol, trifluoroacetic acid and water. The content of acetonitrile is 30 to 40% by volume relative to the mass of the matrix solution. The content of ethanol is 10 to 20% by volume relative to the mass of the matrix solution. The content of trifluoroacetic acid is 1 to 3% by volume relative to the mass of the matrix solution. The matrix solution contains α-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid or sinapic acid in an amount of 5 to 20 mg/ml.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
G01N 33/483 - Physical analysis of biological material
A gas measurement device (1) includes: a first detection unit (120) for detecting a first component in a sample gas; and a second detection unit (140) for detecting a second component and a third component, respectively, which are components interfering with the first component. The first detection unit includes a first sample cell (122) and a first detector (10A) which are arranged in series on a first optical path (IR1) of light emitted from a first light source (124). The second detection unit (140) includes a second sample cell (142), a second detector (10B) and a third detector (10C), which are arranged in series on a second optical path (IR2) of light emitted from a second light source (144).
G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
26.
GAS MEASUREMENT DEVICE, AND METHOD FOR DETERMINING CONCENTRATION OF COMPONENT OF INTEREST
The concentration of each of a plurality of gas components is expressed as a corrected concentration obtained by subtracting, from a pre-correction concentration corresponding to a detected value for said gas component, a measurement error to which the measurement of said gas component is subject due to one or more interfering components affecting said gas component. The measurement error to which the measurement of the gas component is subject is expressed by a linear sum of corrected concentrations of the interfering components affecting said gas component and influence coefficients indicating the degree to which said interfering components influence the measurement of said gas component. According to the relationship between the corrected concentration and the pre-correction concentration for each of the plurality of gas components, the concentration of a component of interest is determined on the basis of the multiple influence coefficients and the respective detected values for said plurality of gas components.
G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
This X-ray imaging device (100) comprises: an X-ray tube (1) including a target (30), an electron beam emitting unit (11), and a vacuum container (15); a detector (2); a subject placement unit (3); and an image processing unit (5). The target includes an X-ray generation unit (32) that generates X-rays and a heat dissipation layer (33) provided on the surface (32a) of the X-ray generation unit on the side of the electron beam emitting unit. The thermal conductivity in the plane direction of the heat dissipation layer is greater than the thermal conductivity in the thickness direction of the heat dissipation layer.
G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
This recovery solution generating device comprises: a combustion tube (16) for generating a recovery target component by burning a sample; a carrier gas supply unit (23) for supplying a carrier gas to the combustion tube (16) and causing the recovery target component generated in the combustion tube (16) to flow out from an outlet of the combustion tube (16) by means of the carrier gas; an absorption unit (6) including a plurality of absorption tubes (30) each accommodating an absorption liquid for absorbing and recovering the recovery target component, and an absorption tube selection valve (34) for selecting one of the absorption tubes (30) to be fluidly connected to the outlet of the combustion tube (16), from among the plurality of absorption tubes; and a control unit (36) for controlling the operation of the absorption unit (6) such that the recovery target component generated from the sample introduced into the combustion tube (16) is recovered by a prescribed one of the absorption tubes (30).
A sample plate holder (6) for a mass spectrometry device comprises: urging members (631 to 633) for pushing one surface of a sample plate toward another surface thereof at three locations that are not positioned on a straight line; and abutting members (612 to 614) which abut said other surface of the sample plate (5) in positions corresponding to the three locations as seen in a plan view. The sample plate holder (6) can suitably be employed in a mass spectrometry device (1) comprising: a laser light emitting unit (13) for emitting laser light onto a sample placed on the sample plate; and a mass spectrometry unit (30) for performing mass spectrometry of ions generated from the sample (S) as a result of the emission of the laser light.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/00 - Particle spectrometers or separator tubes
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
H01J 49/16 - Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
This automatic analysis system comprises: an analysis unit (10) capable of selectively executing a general sample analysis or an accuracy management analysis; a display input unit (30); a time setting storage unit (40) in which setting relating to the execution time for the accuracy management analysis is stored; a display control unit (50) that displays a postponement instruction key on the display input unit at a prescribed timing earlier than the execution time determined on the basis of the setting stored in the time setting storage unit; and a postponement control unit (60) that postpones the execution time on the basis of prescribed operation having been performed on the postponement instruction key. Accordingly, it is possible to perform appropriate analysis management according to a situation in an automatic analysis device that performs an accuracy management analysis at the preset time.
The present invention is an analysis system 1 comprising: an analysis device 10 for performing analyses by mixing reagents in reagent containers 114 held by a reagent-holding unit 111 with test specimens in specimen containers held by a specimen-holding unit 121; and a data processing device 30 having a temperature information collection part 310 for collecting temperature information pertaining to the reagent-holding unit via a data communication network 20. The data processing device comprises: a display unit 33 for displaying a screen showing the temperature information collected by the temperature information collection part; a temperature determination part 313 for determining whether or not the temperature of the reagent-holding unit has deviated from a predetermined temperature range on the basis of the temperature information; and a display control part 314 for causing the display screen showing the temperature information to pop up as it is determined by the temperature determination part that the temperature of the reagent-holding unit has deviated from the predetermined temperature range.
This underwater optical wireless communication system (100) comprises: a first communication device (2) that rotates underwater together with a rotating body (1); and a second communication device (3) that wirelessly communicates with the first communication device in a direction intersecting a rotation axis (60) of the rotating body, wherein the first communication device has a first light emitting unit (20) that emits first light (50), and a first information conversion unit (21) that converts, to the first light, state information input from a state information detection unit (4) which detects state information (40) serving as information pertaining to the state of the rotating body, and the second communication device has a second light receiving unit (30) that receives the first light.
H04B 10/80 - Optical aspects relating to the use of optical transmission for specific applications, not provided for in groups , e.g. optical power feeding or optical transmission through water
G08C 15/06 - Arrangements characterised by the use of multiplexing for the transmission of a plurality of signals over a common path successively, i.e. using time division
33.
IMAGING ANALYSIS METHOD AND DEVICE USING ION MOBILITY MASS SPECTROMETRY
An embodiment of an imaging analysis device according to the present invention comprises: a measurement unit that acquires analysis result data by performing ion mobility mass spectrometry for each micro-region in a predetermined measurement region of a sample; a correlation investigation unit (22, 23) that investigates a correlation between m/z and ion mobility in the analysis result data acquired by the measurement unit on the basis of said data; and a data reduction unit (24, 25) that reduces the amount of the analysis result data by limiting an ion mobility range according to m/z or limiting an m/z range according to ion mobility, on the basis of the correlation result acquired by the correlation investigation unit.
A detecting mechanism (110) acquires first information indicating the position of a cantilever in the Z-axis direction and second information indicating the position of a sample S in the Z-axis direction or the position of a sample stand (14) in the Z-axis direction. An approach processing part (104) determines a speed reduction position on the basis of the first information and the second information. The approach processing part (104) controls a displacement mechanism so that an approach speed changes from high speed to low speed at the speed reduction position.
Provided is a technology for identifying the type of a correction according to the state of the surface of a sample, an image of which has been generated on the basis of the measurement using a scanning probe microscope An image processing method according to the present invention comprises a step (SA1) for generating a corrected image by performing a first correction on a target image. The first correction includes extracting, from the target image, a plurality of pixels on a straight line along a prescribed direction on a prescribed plane and correcting the height of the target image on the basis of the luminance of each of the pixels extracted. The image processing method further comprises: a step (SA3) for generating a histogram of the pixel values in the corrected image; and a step (SA4) for using the histogram to determine whether or not a second correction, which is different from the first correction, is necessary on the target image.
In the present invention, when a cap is being attached to a container, an operation unit grips the cap while contacting the top surface of the cap, on which a threaded portion is formed, and brings the gripped cap into contact with the container. A buffer unit absorbs pressing force applied from the cap to the operation unit. A control unit executes, in order: a control for causing a rotation-driving unit to rotate in a first direction, thereby fastening the cap gripped by the operation unit onto the container; a control for causing the rotation-driving unit to rotate in a second direction, thereby loosening the cap gripped by the operation unit from the container; and a control in which the rotation-driving unit is rotated in the first direction, as a result of which the cap gripped by the operation unit is fastened onto the container.
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
B67B 1/06 - Closing bottles, jars, or similar containers by applying stoppers by inserting and rotating screw stoppers
B67B 3/20 - Closing bottles, jars, or similar containers by applying caps by applying and rotating preformed threaded caps
B67B 7/18 - Hand- or power-operated devices for opening closed containers for removing threaded caps
The present invention comprises: a reference value searching step for searching for a reference value R from among N measurement values; a selection step for selecting M measurement values by excluding, from the estimation target, N-M measurement values, as outliers, in descending order of deviation from the reference value R, among the N measurement values, on the basis of the reference value R searched for in the reference value searching step; and an estimation value calculation step for setting an average value of the M measurement values selected in the selection step as an estimation value of a true value. The reference value searching step includes a loop repeating from a state n=N until n=1, a process for determining the median or average value of the n measurement values, excluding one measurement value with the largest deviation from the median value or the average value among the n measurement values, and setting n-1 measurement values as candidates for the reference value R, and after the loop ends, one last remaining measurement value as the candidate is set as the reference value R.
A mass spectrometry device 100 is provided with: measurement execution units 1, 2, 62 that isolate and detect, in accordance with the mass-to-charge ratio, product ions generated by emitting oxygen radicals, hydroxyl radicals, or nitrogen radicals against precursor ions derived from a sample component; a candidate molecule inferring unit 63 for determining, on the basis of the mass-to-charge ratio of the precursor ions, a candidate molecule under the assumption that the sample component is a compound having a heterocyclic ring that includes a double bond between carbon atoms; a hypothetical product ion inferring unit 64 for calculating the mass-to-charge ratio of hypothetical product ions assumed to be produced through cleavage of a heterocyclic ring pertaining to the precursor ions of the candidate molecule or cleavage of a bond adjacent to the heterocyclic ring; and a determination unit 65 for determining whether or not the sample component is the candidate molecule by comparing the mass-to-charge ratio of the detected product ions and the mass-to-charge ratio of the hypothetical product ions.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
39.
ACCELERATED DETERIORATION TEST DEVICE, ACCELERATED DETERIORATION TEST ANALYSIS SYSTEM, AND ACCELERATED DETERIORATION TEST METHOD
This accelerated deterioration test device (101) comprises: a storage container (10) that is capable of, for an accelerated deterioration test in which sample deterioration is accelerated by a deterioration factor that deteriorates a sample (200) to be tested, accommodating the sample (200) to be subjected to the accelerated deterioration test; and an introduction and collection unit (120) that is connected to the storage container (10) to carry out, during the accelerated deterioration test, introduction of a gas or a liquid as the deterioration factor into the storage container (10) and collection of a product generated with deterioration of the sample (200).
Provided is a microorganism classifying method including: a step (S1) for obtaining a first mass spectrum, which is obtained by performing mass spectrometry of a first microorganism that is cultured under conditions for producing an acid-shock protein and that is of an order of intestinal bacteria for which classification is unknown at one of family, genus, and species and levels therebelow; a step (S2) for obtaining a first m/z corresponding to the acid-shock protein from the first mass spectrum; and a step (S3) for analyzing the first m/z and performing, regarding the first microorganism, classification at one of the unknown levels and therebelow.
C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
41.
CALIBRATION METHOD, ANALYSIS METHOD, CONTROL DEVICE, AND ANALYSIS DEVICE
This calibration method is for calibrating a mass spectrum for mass spectrometry of a microbial sample containing a substance to be analyzed, i.e. molecules to be analyzed, said calibration method including: a step (S31) of acquiring a mass spectrum of a microbial sample to which one or more molecules having an estimated theoretical m/z smaller than that of the substance to be analyzed have been added as a first standard substance; a step (S32) of setting, as a second standard substance, one or more molecules which are derived from the microbial sample and have an estimated theoretical m/z larger than that of the substance to be analyzed; and a step (S33) of calibrating the mass spectrum on the basis of an actually measured m/z of the first standard substance and an actually measured m/z of the second standard substance as indicated by peaks on the mass spectrum, the theoretical m/z of the first standard substance, and the theoretical m/z of the second standard substance.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
42.
METHOD FOR PREPARING ANALYSIS OF MICROORGANISMS, AND METHOD FOR ANALYZING MICROORGANISMS
This method for preparing an analysis of microorganisms using an acid shock protein comprises: a step (S1) for preparing at least one culture medium containing a pH indicator; a step (S2) for inoculating microorganisms into the culture medium; a step (S3) for culturing the microorganisms in the culture medium under specific conditions; a step (S4) for identifying the color of the culture medium, and detecting, on the basis of the identification result, the time when the microorganisms produce acid shock proteins; and a step (S5) for recovering the microorganisms for analysis at the time when acid shock proteins are produced.
C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
C12Q 1/24 - Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganism
G01N 33/483 - Physical analysis of biological material
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
This estimation method includes: a step for acquiring a measurement value of advanced glycation end products of a measured person; and a step for estimating the blood glucose spike frequency of the measured person on the basis of the measurement value of the advanced glycation end products of the measured person acquired in the acquiring step, using a correlation between the measurement value of advanced glycation end products and blood glucose spike frequency prepared beforehand.
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G01N 33/66 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
G16H 10/00 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data
44.
METHOD FOR PREPARING SAMPLE FOR ANALYSIS AND METHOD FOR ANALYZING SAME
Provided is a method for analyzing an O-linked sugar chain that has been undergone sialic acid linkage-specific modification, the method comprising: a modification step for adding a modifier, which performs sialic acid linkage-specific modification on the O-linked sugar chain, to a sample containing a glycoprotein to which the O-linked sugar chain is linked; a release step for releasing, from the glycoprotein, the O-linked sugar chain that has been undergone the sialic acid linkage-specific modification; and an analysis step for analyzing the released O-linked sugar chain that has been undergone the sialic acid linkage-specific modification.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
An advice apparatus (50) comprises a computation device (510) and a communication device (530) that is connected to the computation device (510) so as to be able to communicate therewith. The communication device (530) acquires a measurement value of an advanced glycation end product of a measurement subject, and a plurality of items of other data that relate to the measurement subject that are different from the measurement value of the advanced glycation end product. The computation device (510) generates advice information that relates to the life of the measurement subject on the basis of the measurement value of the advanced glycation end product acquired by the communication device (530), and at least one item of other data from among the plurality of items of other data acquired by the communication device (530).
G16H 20/00 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
The present invention provides a mass spectrometry method comprising: a preparation step (step 1) for adding prescribed alkali metal ions to a liquid sample; an ionization step (step 3) for ionizing a target compound contained in the liquid sample to which the alkali metal ions have been added; and a measurement step (step 7) for measuring the intensity of adduct ions obtained by adding the prescribed alkali metal to the target compound that has been generated in the ionization step or of product ions derived from the adduct ions.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
G01N 30/26 - Conditioning of the fluid carrier; Flow patterns
H01J 49/00 - Particle spectrometers or separator tubes
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
H01J 49/42 - Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
This method for structural analysis of a sample molecule is a method for analyzing the structure of a sample molecule using a mass spectrometer provided with a MALDI-type ion source, an ion-capturing unit for capturing ions having a prescribed mass-to-charge ratio from among the ions produced by the ion source, and a detection unit for detecting the ions captured by the ion-capturing unit, the method having: a step for acquiring standard analysis conditions for an ion amount setting item, a mass-to-charge ratio range setting item, and a signal intensity setting item for performing a molecular weight-related ion measurement; a step for performing a product ion measurement under a modified analysis condition in which an analysis condition for at least one of the ion amount setting item, the mass-to-charge ratio range setting item, and the signal intensity setting item from among the standard analysis conditions has been modified, and acquiring mass spectral data for the product ion measurement; a step for extracting a peak corresponding to fragment ions from the mass spectral data; and a step for determining at least a part of the structure of the sample molecule on the basis of mass information for the extracted peak. It is thereby possible to detect, at a high sensitivity and in a prioritized manner, fragment ions necessary for structural analysis.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
H01J 49/00 - Particle spectrometers or separator tubes
H01J 49/02 - Particle spectrometers or separator tubes - Details
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
H01J 49/16 - Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
H01J 49/42 - Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
48.
LASER LIGHT IRRADIATION DEVICE AND LASER PROCESSING DEVICE
A laser light irradiation device (1) comprises a plurality of laser light sources (10), an optical fiber (30), and a coupling optical system (20). The coupling optical system (20) includes a reducing optical system (22). The reducing optical system (22) includes a lens (23a) and a lens (24a). The lens (23a) is formed from a first glass material. The lens (24a) is formed from a second glass material. A second energy gap of the second glass material is greater than a first energy gap of the first glass material.
This nucleic acid mass spectrometry method has: a step for preparing an analysis specimen which contains a matrix substance, a matrix additive which is diammonium hydrogen citrate, and a specimen containing a nucleic acid; and a step for analyzing the analysis specimen by using a matrix-assisted laser desorption/ionization mass spectrometer of the ion trap type. As a result, it is possible to increase nucleic acid analysis sensitivity in comparison to conventional methods.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
This nucleic-acid structural analysis method utilizes an ion trap mass spectrometer having an ion source based on MALDI, the method including: an ionization step for ionizing with the ion source a nucleic acid contained in a sample; an ionic dissociation step for dissociating a protonated molecule or a deprotonated molecule of the nucleic acid, generated in the ionization step, by collision-induced dissociation inside the ion trap in the mass spectrometer, to generate a plurality of fragment ions; a mass analysis step for carrying out mass analysis on the plurality of fragment ions generated in the ionic dissociation step, to acquire mass information about the plurality of fragment ions; and a structure-determining step for determining at least a part of the structure of the nucleic acid, on the basis of the mass information about the plurality of fragment ions acquired in the mass analysis step. This can provide a novel nucleic-acid structural analysis method by which fragment ions can be detected with advanced sensitivity.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
C12Q 1/6872 - Methods for sequencing involving mass spectrometry
51.
NUCLEIC ACID ANALYSIS METHOD AND MATRIX USING SAME
In the present invention, a nucleic acid included in a sample is analyzed by a matrix-assisted laser desorption/ionization mass spectrometer using a mixed matrix that includes 3-hydroxypicolinic acid and 2,4-dihydroxyacetophenone, or a mixed matrix that includes 3-hydroxypicolinic acid and 2,4,6-trihydroxyacetophenone monohydrate. It is thereby possible to detect [M+H]+or [M-H]- of the nucleic acid and a fragment ion generated by desorption of said ion with high sensitivity.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
52.
METHOD FOR PREPARING SAMPLE SOLUTION CONTAINING NEUROGRANIN-RELATED PEPTIDE, AND METHOD FOR ANALYZING NEUROGRANIN-RELATED PEPTIDE
Provided are: a method which is for analyzing a neurogranin-related peptide and can suppress deviations in analysis results; and a method for preparing a biological sample containing the neurogranin-related peptide used for same. A method for preparing a sample solution containing a neurogranin-related peptide involves mixing a biological sample containing the neurogranin-related peptide with an organic solvent having a relative polarity of 0.200 to 0.700 to prepare a sample solution containing the organic solvent having a final concentration of at least 5.0 (v/v)%.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups
53.
CIRCULATION DEVICE FOR TWO-PHASE COOLING SYSTEM AND REFRIGERANT CIRCULATION METHOD IN CIRCULATION DEVICE FOR TWO-PHASE COOLING SYSTEM
A circulation device (100) for a two-phase cooling system comprises: an inlet-side connection portion (41) and an outlet-side connection portion (42); and a bypass flow path (75) that branches downstream of a pump (10) and upstream of the inlet-side connection portion and allows a refrigerant to flow to a condenser (20) without passing through the inlet-side connection portion or the outlet-side connection portion, wherein in a state in which an evaporator (80) is not connected to the inlet-side connection portion and the outlet-side connection portion, the refrigerant is circulated through the bypass flow path without passing through the inlet-side connection portion and the outlet-side connection portion.
F28D 15/02 - Heat-exchange apparatus with the intermediate heat-transfer medium in closed tubes passing into or through the conduit walls in which the medium condenses and evaporates, e.g. heat-pipes
This correction method is for an analyzer that uses a wavelength dispersion-type X-ray spectrometer. This analyzer stores standard sensitivity data including a relationship between the wavelength and the intensity of a characteristic X‐ray generated from a standard sample. This correction method comprises: a step for acquiring actual measurement data indicating the result of actually measuring wavelengths and intensities for two or more different characteristic X‐rays in the standard sample; and a step for calculating an intensity ratio (C3) of an intensity with respect to a prescribed wavelength in the actual measurement data to an intensity with respect to a corresponding wavelength in the standard sensitivity data, and for correcting the standard sensitivity data on the basis of the intensity ratio (C3).
G01N 23/2209 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material using wavelength dispersive spectroscopy [WDS]
G01N 23/225 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material using electron or ion microprobes
This X-ray phase imaging device (100) comprises: an x-ray source (1); an x-ray detector (2); a plurality of lattices; an image processing unit (7a) that generates a first dark field image (35a); a storage unit (8) that stores a plurality of correction curves (20a) that are respectively generated at positions in a direction orthogonal to a lattice direction; and a control unit (7b) that uses the plurality of correction curves corresponding respectively to the positions to correct the first dark field image. Each of the plurality of correction curves indicates, at such positions, a correspondence relationship between a value relating to the x-ray absorption of a subject (90) and a value relating to x-ray dispersion.
G01N 23/041 - Phase-contrast imaging, e.g. using grating interferometers
G01N 23/083 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and measuring the absorption the radiation being X-rays
56.
GREENHOUSE GAS MEASURING METHOD AND MEASURING DEVICE
G01N 30/88 - Integrated analysis systems specially adapted therefor, not covered by a single one of groups
G01N 27/626 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using heat to ionise a gas
G01N 27/68 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode using electric discharge to ionise a gas
This chromatograph liquid delivery system includes a liquid delivery unit, a pressure acquiring unit, a maximum value identifying unit, a minimum value identifying unit, and a detecting unit. The liquid delivery unit includes one or more plunger pumps, and is periodically driven to deliver a mobile phase. The pressure acquiring unit acquires a pressure of the mobile phase at a plurality of time points during each drive cycle of the liquid delivery unit. The maximum value identifying unit identifies a maximum pressure, among the pressures acquired by the pressure acquiring unit, for each drive cycle of the liquid delivery unit. The minimum value identifying unit identifies a minimum pressure, among the pressures acquired by the pressure acquiring unit, for each drive cycle of the liquid delivery unit. The detecting unit detects a liquid feed failure resulting from contamination of bubbles into the one or more plunger pumps, on the basis of the identified maximum pressure and minimum pressure.
This method for processing a coaxial cable (60) for applying voltage to a time-of-flight mass spectrometer (10) includes a folding processing step S2 and a burying processing step S3. In the folding processing step S2, in a coaxial cable (60) comprising a central conductor (62), an insulator (64) provided around the central conductor (62), a shield wire (66) provided around the insulator (64), and an outer sheath (68) provided around the shield wire (66), a folded portion (66a) is formed by folding a leading end of the shield wire (66) toward the outer sheath (68). In the burying processing step S3, an insulative or semiconductive member (74) to be buried is disposed in a gap (72) between the folded portion (66a) and the insulator (64).
Provided is a degreasing apparatus 100 with which maintenance can be performed at an appropriate time to ensure the maximal operation time of the apparatus, and even when an unexpected abnormality occurs, the factor of the abnormality can more accurately be identified. For that purpose, the apparatus comprises: a heating furnace 1 for accommodating and degreasing an object W to be treated; a measurement device 2 for measuring the amount of generated gas that has been generated in the degreasing, or a value that indirectly represents same (hereinafter, will be referred to as the generated gas amount); and an information processing device 7 for calculating, on the basis of the generated gas amount that has been measured by the measurement device 2, management information that is information relating to management including an inspection/maintenance time.
This fluorescent X-ray analysis method includes: a step for disposing a sample in a fluorescent X-ray analysis apparatus (S1); a step for applying a desired dead time rate to a paralyzed model and calculating a reference tube current of an X-ray tube (S3); a step for determining a measurement tube current of the X-ray tube on the basis of the reference tube current and causing the measurement tube current to flow in the X-ray tube to irradiate the sample with an X-ray (S4); and a step for analyzing a fluorescent X-ray obtained by irradiating the sample with the X-ray (S5). As a result, a desired dead time of a counting circuit can be accurately obtained.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
A fluorescent X-ray analysis device (10) includes: a sample stage (2); an X-ray tube (7) that is configured so as to radiate excitation X-rays toward the sample stage (2); a detector (8) that detects fluorescent X-rays emitted from a sample on the sample stage; and a control device (14) that controls the X-ray tube (7) and the detector (8). When creating a calibration curve by radiating the excitation X-rays on a standard sample from the X-ray tube (7), the control device (14) issues a warning in the case in which the values of IR/IC obtained with respect to the standard sample fall outside a reference range, assuming that the intensity of X-rays that undergo Rayleigh scattering is IR and the intensity of X-rays that undergo Compton scattering is IC, said X-rays being the results of the sample (S) on the sample stage (2) scattering fluorescent X-rays emitted from the X-ray tube (7) with respect to an X-ray tube bulb target material.
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
One aspect of the present invention is provided with: a LIT (4) that captures specimen-derived ions in a capture space along a linear axis (100) and that emits some of the ions in a direction substantially orthogonal to the axis through an exit port that is elongate in the axis direction; an ion guide part (8) that receives the ions emitted from the LIT and passes the ions to the next stage, said ion guide part having an ion inlet for receiving the ions emitted through the exit port, an ion outlet for sending the received ions and/or ions generated from the received ions to the next stage, and an ion channel the cross-section area of which is reduced as the ions progress from the ion inlet to the ion outlet, and said ion guide part being configured so that the longitudinal size of the exit port in the inlet-side cross section of the ion channel is larger than the longitudinal size of the exit port in the outlet-side cross section of the ion channel; a bunching part (5) that forms an ion bunch by bunching the ions emitted from the ion outlet of the ion guide part and sends said ion bunch downstream; and mass spectrometry parts (6, 7) for splitting, according to m/z, ions contained in the ion bunch formed and sent by the bunching part and detecting the ions.
An embodiment of the mass spectrometer according to the present invention comprises: a first LIT (3) which includes multiple electrodes extending along an axis, traps ions derived from a sample into a trapping space surrounded by these multiple electrodes, and axially emits ions included in a predetermined first m/z width among the trapped ions; a second LIT (4) which includes multiple electrodes extending along the axis, traps the ions emitted from the first LIT into a trapping space surrounded by these multiple electrodes, and emits ions included in a second m/z width, which is narrower than the first m/z width, among the trapped ions; a bunching unit (5) which carries out bunching of the ions emitted from the second LIT and/or ions generated from these ions to form an ion bunch and sends out the ion bunch to the downstream side; a mass spectrometry section (6, 7) which separates the ions included in the ion bunch sent from the bunching unit in accordance with m/z values and detects the separated ions; and a control section (9, 10) which synchronizes the operation of emitting the ions from the first LIT with the operation of emitting the ions from the second LIT and drives both LITs such that the ions are supplied from the first LIT to the second LIT before the ions trapped by the second LIT are all emitted, and the m/z values of the ions respectively emitted from the first LIT and the second LIT change.
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
Teramoto, Kanae
Sekiguchi, Yuji
Miura, Daisuke
Abstract
A microorganism identification method comprising: a step (ST32) for obtaining a sample list that is a list of mass-to-charge ratios of samples; steps (ST40-ST44, ST40A) for identifying a sample by comparing the sample list with a mass-to-charge ratio database, which is a database of mass-to-charge ratio list for each microorganism predicted from genomic data, weighted by the mass-to-charge ratio corresponding to proteins in a specific group; and steps (ST50, ST54) for outputting the identified result.
C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
65.
METHOD AND APPARATUS FOR CONSTRUCTING DATABASE FOR MICROBIAL IDENTIFICATION
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
Inventor
Teramoto, Kanae
Ogata, Koretsugu
Sekiguchi, Yuji
Miura, Daisuke
Abstract
Provided is a method for constructing a database for microbial identification, the method comprising: a step (ST02) for acquiring genome data of a microorganism from a genome database; a step (ST06) for determining whether the acquired genome data satisfies criteria; a step (ST16) for predicting a protein to be expressed, for each genome data determined to satisfy the criteria; and a step (ST20A, 20C) for constructing a mass-to-charge ratio database, including a list of mass-to-charge ratios for each genome data, predicted on the basis of the predicted protein.
A mass spectrometer according to one aspect of the present invention comprises: a LIT (4) that captures ions originating from a sample in a capture space stretching along a linear axis (100) and that emits some of the ions from the capture space to the outside; an ion guiding part (8) that receives the ions emitted from the LIT and delivers the ions to a subsequent stage, the ion guiding part (8) having an ion inlet through which the emitted ions are received, an ion outlet which transmits the received ions and/or ions produced from the received ions to a subsequent stage, and an ion passage route having a cross-sectional area that is reduced in conjunction with ions from the ion inlet advancing toward the ion outlet; a bunching part (5) that gathers ions emitted from the ion outlet of the ion guiding part to form an ion bunch, and transmits the ion bunch to the downstream side; and mass spectrometry units (6, 7) that, according to m/z, separate and detect ions contained in the ion bunch which has been formed and transmitted by the bunching part.
G01N 3/303 - Investigating strength properties of solid materials by application of mechanical stress by applying a single impulsive force generated only by free-falling weight
H01J 49/06 - Electron- or ion-optical arrangements
A holder (H) holds a battery (B) which is to be subjected to X-ray analysis. The battery (B) includes a positive electrode (B1) and a negative electrode (B2). The holder (H) is formed inside a sample chamber (R) in which the battery (B) is disposed. The holder (H) comprises a body (4), a beryllium plate (1), first resin members (2A, 2B), a conductive member (3), a positive electrode terminal (T1), and a negative electrode terminal (T2). A window (W) is formed in an upper surface of the body (4). The beryllium plate (1) is disposed at the window (W). The first resin members (2A, 2B) are each provided on a surface of the beryllium plate (1). The conductive member (3) is provided between the positive electrode (B1) and the first resin member (2B) so as to contact the positive electrode (B1) of the battery (B). The positive electrode terminal (T1) is electrically connected to the conductive member (3). The negative electrode terminal (T2) is electrically connected to the negative electrode (B2).
G01N 23/2209 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material using wavelength dispersive spectroscopy [WDS]
G01N 23/223 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by measuring secondary emission from the material by irradiating the sample with X-rays or gamma-rays and by measuring X-ray fluorescence
311 and a metabolite thereof in a blood sample, the method comprising: a first pretreatment step (S1) for subjecting the blood sample to protein removal by a denaturation method; a second pretreatment step (S2) for removing contaminants contained in the sample obtained after the first pretreatment step by solid phase extraction; and a measurement step (S3,S4) for performing LC/MS analysis for selectively detecting a monovalent protonated ion derived from each of the target components while separating the components in the sample obtained after the second pretreatment step over time by employing LC-MS/MS having an ion source by ESI method.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
G01N 33/82 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins
69.
X-RAY IMAGE PROCESSING DEVICE, X-RAY IMAGE PROCESSING METHOD, AND PROGRAM
In this x-ray image processing device (100), a display control unit (29) displays an entire x-ray image (141) and a partial x-ray image (142) corresponding to a selected vertebral body (40) alongside on a display unit (101), or displays the entire x-ray image (141) and the partial x-ray image (142) corresponding to the selected vertebral body (40) in a switching manner on the display unit (101).
Provided is a contactless-type sleep state measurement system 100 capable of accurately measuring the sleep state of a subject irrespective of the age, disorder, or the like of the subject. The contactless-type sleep state measurement system 100 is provided with: a frame image acquisition unit that acquires frame images including a subject P at sleep chronologically; a difference information calculation unit that calculates difference information which is information indicating a difference between two frame images at different times; a subject attribute information acquisition unit that acquires subject attribute information which is information indicating an attribute of the subject; and a sleep state-related information calculation unit that, in accordance with the subject attribute information, and by using the difference information or secondary information obtained therefrom as an explanatory variable, calculates sleep state-related information which is information related to the sleep state of the subject.
A computer (132): acquires image data (step S10); extracts, as edge pixels, pixels that satisfy a condition in which a comparison result with adjacent pixels from the image data is an edge (step S12); and generates first data by executing extension processing that extends the edge composed of the corresponding edge pixels (step S14). In addition, the computer (132) generates second data that specifies an area corresponding to a substrate in a specimen by using the first data (step S22).
An image processing unit (2) of this X-ray image processing device (100) comprises: a position estimation unit (22) that estimates an evaluation position for evaluating the shape of a centrum (40), from a centrum-specific image (130) generated by a centrum-specific image generation unit (21); and an image generation unit (23) that generates a centrum shape evaluation image (140) including the centrum (40) and the evaluation position.
This evaluation method includes: a step for acquiring information related to a task to be executed by a subject (step S10); a step for acquiring biological information of the subject (step S12); a step for specifying a timing at which the biological information satisfies a predetermined condition (step S14); a step for outputting a portion that is of the information related to the task and that corresponds to the specified timing (step S24); and a step for accepting input of feedback related to the task (step S26).
An atomic absorption spectrophotometer (1) comprises: a sample collecting part (24) to which a chip (25) for collecting and discharging a sample is attached; a sample heating part (11), wherein an opening (14) into which the sample is injected is provided on the top surface of the sample heating part; a moving mechanism (27) that moves the sample collecting part between a first position at which the sample is collected into the chip and a second position at which the sample is injected from the chip into the opening; a light irradiation part (29) that irradiates the opening with light from a predetermined direction; and an image acquisition part (26) that images the opening from an optical axis direction different from the central axis of light emitted from the light irradiation part.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
75.
MONITORING ANALYSIS DEVICE AND MONITORING ANALYSIS METHOD
This monitoring analysis device comprises: a reaction product acquisition unit that sequentially acquires reaction products generated by a reaction device; an analysis unit that sequentially analyzes the reaction products acquired by the reaction product acquisition unit; an analysis control unit that causes the analysis unit to execute batch analysis for sequentially performing a plurality of analyses set under preset analysis conditions; and an analysis condition change unit that is configured so as to be able to change, during execution of the batch analysis by the analysis unit, analysis conditions set for an analysis to be changed which is executed after any analysis, such change carried out during or after execution of the any analysis among a plurality of set analyses.
This cell culture apparatus (100) comprises a device holder (101), and a plurality of gas pipes (31) for supplying gas to a culture chamber (23). The device holder includes a holder-side lid part (10) having mounting parts (30) for the plurality of gas pipes and a plurality of holder-side ports (11). The holder-side lid part is configured to be movable between: a connection position at which the plurality of gas pipes and the plurality of holder-side ports are respectively connected to a plurality of device-side ports (21) of the device-side lid part (25) of the cell culture device (20); and a connection release position at which the connection is released.
Provided is a technique for providing objective and highly accurate information about assessment of taste. The present invention involves acquiring, by a device, information about respective amounts of two or more components in a target object (step S21). The two or more components are associated with a specific taste. The device derives the result of determination of whether or not a target object has a specific taste, on the basis of proportion information about proportions of the two or more components and information about the respective amounts of the two or more components (step S23), and outputs the result of the determination (step S24).
An error reporting system (1) comprises a wearable device (10) and a control device (20) that controls the wearable device (10). The control device (20) compares, process by process, details of work including at least one process and indicated by a work procedure document and details of work indicated by a video recording the appearance of a worker performing work to identify a difference. The wearable device (10) includes a reporting device (18) that reports an error when a difference is identified.
G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer
G05B 19/418 - Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control (DNC), flexible manufacturing systems (FMS), integrated manufacturing systems (IMS), computer integrated manufacturing (CIM)
G06Q 10/06 - Resources, workflows, human or project management; Enterprise or organisation planning; Enterprise or organisation modelling
H04N 5/64 - Constructional details of receivers, e.g. cabinets or dust covers
H04N 13/344 - Displays for viewing with the aid of special glasses or head-mounted displays [HMD] with head-mounted left-right displays
There is provided a highly flexible sterilization method that is also safe and optimal. This sterilization method includes sterilization area setting in order to set in advance a sterilization area within a predetermined area of human activity, peripheral area setting in order to set in advance peripheral areas that are adjacent to or in proximity to the sterilization area, irradiation mode deciding in order to decide an irradiation mode for irradiating sterilization electromagnetic waves onto the sterilization area based on peripheral area information acquired from the peripheral areas, and sterilization electromagnetic wave irradiating in order to irradiate sterilization electromagnetic waves onto the sterilization area in the irradiation mode.
A61L 2/02 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
Provided is a method for measurement of a measurement sample containing hypochlorite ion by liquid chromatography-mass spectrometry, said method comprising determining the abundance of hypochlorite ion by selecting a mass chromatogram that indicates the presence of a hypochlorite ion-derived complex from a plurality of mass chromatograms obtained by liquid chromatography-mass spectrometry.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
This method tests for the presence/absence of the SARS-CoV-2 virus and influenza A/B virus, said method comprising: a step for preparing a mixed liquid by mixing a test specimen processing liquid with a test sample; a step for preparing a PCR solution by mixing the mixed liquid with a buffer solution, an internal standard substance, a SARS-CoV-2 primer, a SARS-CoV-2 probe, an influenza A primer, an influenza A probe, an influenza B primer, an influenza B probe, a reverse transcriptase, and a PCR enzyme; and a step for carrying out PCR processing on the PCR solution and detecting light emitted from at least one of the SARS-CoV-2 probe, the influenza A probe, and the influenza B probe. Moreover, a fluorescent dye with which the influenza A probe is modified and a fluorescent dye with which the influenza B probe is modified are the same.
C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
A laser beam condensed by a condensing optical system is incident upon an optical fiber (200). A radiating mechanism (301) radiates light emitted from the optical fiber (200) onto a target object. A movement mechanism (302) causes a radiation region of the laser beam on the target object to move. The optical fiber (200) has a core including a surface of incidence upon which the laser beam condensed by the condensing optical system is incident. The shape of the surface of incidence is a first elongate shape which is longer in a first direction than in a second direction, the first direction and the second direction being orthogonal to one another. The shape of the radiation region is a second elongate shape corresponding to the first elongate shape. The movement mechanism (302) causes the radiation region to move in the first direction.
Provided is a method for analyzing biomolecules present in vesicles, said method involving: bringing vesicles and trapping molecules immobilized in a support body into contact; bringing the vesicles and first detection molecules labeled with first metal particles into contact; bringing the vesicles and second detection molecules labeled with second metal particles into contact; and quantifying the first metal particles and the second metal particles bound to the vesicles by means of inductively coupled plasma (ICP) mass spectrometry or ICP emission spectroscopy.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
Provided is a nucleic acid structure analysis method comprising: a HAD-MSnanalysis step (101) of dissociating ions derived from a test nucleic acid by introducing hydrogen radicals into a space containing the ions, and performing mass spectrometry of a plurality of thus generated fragment ions to collect information on the m/z of the plurality of fragment ions; and a structure estimation step (103) of estimating the structure of the test nucleic acid on the basis of the information on the m/z of the plurality of fragment ions obtained in the HAD-MSn analysis step. The present invention thereby makes it possible to handle precursor ions of various electric charges and facilitate structure estimation of nucleic acids based on mass spectra.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
The purpose of the present invention is to suppress accuracy deterioration resulting from the influence of noise light. A spectroscopic device (1) comprises: a light source (2); a quantum optical system (4) that has one or more nonlinear optical elements (12) for generating a photon pair of idler light and signal light from pump light by an entangled photon pair generation process and that comprises a sample placement tool (35) for placing a sample (SP) on an optical path of the idler light; and a detection unit (6) that is for detecting the light intensity of light output from the quantum optical system (4); and an analysis device (8). The quantum optical system (4) is configured to emit first and second signal light (s1, s2) through differing optical paths. The detection unit (6) comprises a beam splitter (40) for receiving the first and second signal light (s1, s2) from the quantum optical system (4) and detects the respective light intensities of two light beams emitted from the beam splitter (40). The analysis device (8) acquires an interferogram from the two light beams which have been detected by the detection unit (6).
This method for extracting a biological sample held in a micro flow passage of a chip (114) which internally includes the micro flow passage, both ends of which are open, includes: an immersion step for immersing an end portion of the micro flow passage of the chip (114) in an extracting solvent, in a container (200); and, after the immersion step, an extraction step for extracting the biological sample from the chip (114) into the extracting solvent by shaking the container (200).
G01N 1/00 - Sampling; Preparing specimens for investigation
G01N 35/02 - Automatic analysis not limited to methods or materials provided for in any single one of groups ; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
G01N 37/00 - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES - Details not covered by any other group of this subclass
The present invention provides a mass spectrometer in which an ion source unit for ionizing a liquid sample has: an ion source housing (131); an ion source cover (120) that accommodates said ion source housing (131); ion source cases (110, 216) that accommodate the ion source cover (120); probes (141, 142) that penetrate the ion source cover and the ion source housing and spray the liquid sample into the ion source housing; a heated gas nozzle (150) via which gas heated by a heater (155) provided to the body is discharged into the ion source housing, said heated gas nozzle (150) having a hollow body (151) that is positioned between the ion source cover and the ion source housing; ion source case intake ports (113, 114) and an ion source case exhaust port (212) provided on the ion source cases; ion source cover intake ports (121, 122) and an ion source cover exhaust port (124) provided on the ion source cover; a first exhaust fan (123) with which air having flowed in via the ion source cover intake ports and passed through the inside of the ion source cover is expelled via the ion source cover exhaust port; and a second exhaust fan (214) with which air expelled via the ion source cover exhaust port into the ion source case and air that has flowed in via the ion source case intake ports and passed through the inside of the ion source case is expelled to the exterior via the ion source case exhaust port.
A gas analysis system (1) comprises: an inflow unit (C1) into which sample gas flows; columns (41, 42); detection devices (50, 51) for detecting components of the sample gas; a sampler module (M1) and a switching module (M2) including a plurality of valves (V1 to V10); and a control device (100) for independently controlling the plurality of valves (V1 to V10). The control device (100) includes: a storage unit (120) for storing therein function pattern information that defines the correspondence relationship between a plurality of basic functions and opening/closing patterns of the plurality of valves; and an output unit (110) for outputting control signals respectively to the plurality of valves (V1 to V10) using the function pattern information stored in the storage unit (120).
A gas analysis system (1) comprises: a first flow path (L1) through which sample gas that has passed through columns (41, 42) using helium gas as carrier gas flows; a second flow path (L2) through which the sample gas that has passed through columns (43, 44) using nitrogen gas as carrier gas flows; a TCD (90) that detects components of gas using the difference in thermal conductivity between the components; and a switching module (M3). The switching module (M3) is disposed between the first flow path (L1), the second flow path (L2), and the TCD (90), and is configured to be switchable between a first state in which the TCD (90) is connected to the first flow path (L1) and a second state in which the TCD (90) is connected to the second flow path (L2).
A locking mechanism (300) includes a lever (301) and an engaging portion (302). The lever (301) is provided on either a main body (100) or an ion source (200), and can rotate between a locked state in which the ion source (200) is maintained in a closed state with respect to the main body (100), and an unlocked state in which the ion source (200) can be opened with respect to the main body (100). The engaging portion (302) includes a first engaging member (321) and a second engaging member (322) of which at least one can rotate, the first engaging member (321) and the second engaging member (322) engaging with one another in the locked state. In conjunction with the rotation of the lever (301) from the unlocked state to the locked state, at least one of the first engaging member (321) and the second engaging member (322) rotates while the first engaging member (321) and the second engaging member (322) come into contact with one another.
The purpose of the present invention is to provide a mass spectrometer which makes it possible to easily attach and detach electric wiring of an ion optical element even when another system unit or the like is mounted on the top of the mass spectrometer. This mass spectrometer comprises: a chamber VC that forms a vacuum vessel; an ion optical element MFP that is disposed inside the chamber; and a feeder for feeding power from a power source disposed outside the chamber to the ion optical element. In at least part of a wall surface except the upper surface and the lower surface of the chamber, an opening OP is formed, and a side surface lid VC1 for closing the opening is provided. A connection position between the feeder FT and a cable CA and a connection position between the ion optical element (terminal MT) and the cable CA are set at positions which enable the cable CA to be detached from the opening side in a state where the ion optical element is housed inside the chamber.
H01J 49/42 - Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
The purpose of the present invention is to provide a gas chromatograph mass spectrometer that prevents explosion of hydrogen gas and enhances safety. This gas chromatograph mass spectrometer in which a gas chromatograph unit and a mass spectrometry unit are combined comprises: a supply operation means for starting or stopping the supply of a carrier gas used in the gas chromatograph unit; a vacuum pump for evacuating the inside of an analysis tube of the mass spectrometry unit; and an evaluation means for evaluating the vacuum state in the analysis tube, the gas chromatograph mass spectrometer including a gas supply means for controlling the supply operation means and starting the supply of the carrier gas (S102) when the evaluation means determines that the vacuum state is normal after the drive of the vacuum pump (S101) is started.
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
This X-ray imaging system (100) generates a three-dimensional model (81) of a device (80) on the basis of a first X-ray image (11) and a second X-ray image (12). Furthermore, the X-ray imaging system (100) determines an inaccurately shaped portion in the three-dimensional model (81) by identifying, from the device (80) which has a linear structure, a parallel portion extending along a direction parallel to an epipolar line. Moreover, the X-ray imaging system (100) displays the three-dimensional model (81) and a display that is based on the determination result of the inaccurately shaped portion in the three-dimensional model (81).
A mass spectrometer according to an embodiment of the present invention is capable of executing scanning measurement and comprises: a temporary event time determination unit (310) that determines a temporary event time allocated to a scanning measurement event which is a unit of measurement in which a single scanning measurement is to be performed, depending on analysis conditions specified by a user; a scanning speed selection unit (311) that selects, from a plurality of candidates, a scanning speed such that the measurement time required to perform a single scanning measurement does not exceed the temporary event time of the scanning measurement event; an event time determination unit (312) that modifies the temporary event time of the scanning measurement event to a time required to perform the scanning measurement at the selected scanning speed, and sets the required time as the event time of the scanning measurement event; and control information production units (313-315) that produce control information for controlling the mass spectrometer on the basis of the event time determined by the event time determination unit.
H01J 49/00 - Particle spectrometers or separator tubes
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
This X-ray imaging system (100) is provided with a dose calculation processing unit (70) and a display unit (4). The dose calculation processing unit (70) calculates a dose in each of a plurality of angle regions that are divided at predetermined angle intervals of imaging unit angles on the basis of the distribution of doses on the surface of a virtual model (Pa) and imaging unit angles assigned to the surface of the virtual model (Pa). The display unit (4) is configured so as to display an angular dose image (42) capable of distinguish the level of the calculated dose in each of the plurality of angle regions.
One embodiment of a gas chromatograph (GC) analysis method according to the present invention, which employs a column to separate and detect components contained in sample gas, includes: a sample collecting step (S1-S3) for collecting the sample gas using a headspace method from a solution containing n-alkanes, which are reference compounds for a retention index; a reference compound analysis step (S3) for introducing the sample gas collected in the sample collecting step into the column to perform GC analysis; and a retention time calculating step (S4-S5) for obtaining actual measured retention times for the n-alkanes on the basis of a chromatogram obtained by the GC analysis, and estimating the retention time of a compound being analyzed, from said actual measured retention times and the known retention index of the compound being analyzed. In this way, in a GC analysis method in which sample introduction is performed using the headspace method, it is possible to perform highly accurate compound identification employing retention times corresponding to various compounds in the sample.
The present invention involves: dissolving a dye in a volatile liquid to prepare a dye-containing volatile liquid that contains the dye at a predetermined concentration (step 11); suctioning the dye-containing volatile liquid by a dispenser and discharging the same into a measurement vessel (step 12); drying the dye-containing volatile liquid discharged into the measurement vessel (step 13); adding, after the drying, a predetermined amount of a low-volatile liquid having a volatility lower than that of the volatile liquid to the measurement vessel to dissolve the dye and prepare an assessment liquid (step 14); conducting an optical measurement on the assessment liquid (step 15); and determining a discharged amount that is the volume of the dye-containing volatile liquid discharged into the measurement vessel, on the basis of a measured value of the assessment liquid obtained by the optical measurement, the added amount of the low-volatile liquid, and the concentration of the dye in the dye-containing volatile liquid (step 16). As a result, the amount of a volatile liquid dispensed by a dispenser such as a micropipette can be accurately measured.
This first movement phase is supplied by a movement phase supply unit. A sample is provided by a sample supply unit to the first movement phase supplied by the movement phase supply unit. The sample supplied by the sample supply unit passes through a separation column. The sample that has passed through the separation column is detected by a detector. A component of the sample that has passed through the separation column is captured by a trap column on the basis of a detection result from the detector. A liquid feeding unit supplies a make-up solution to the detector, and supplies an eluting solution for eluting the sample to the trap column.
A method for analyzing a neurogranin-related peptide through matrix-assisted laser desorption/ionization mass spectrometry, wherein: an object being irradiated with a laser contains the neurogranin-related peptide, a matrix, and 9 kDa or more of proteins; and the protein content per 1 µg of the matrix is 10-600 fmol inclusive.
G01N 27/62 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electric discharges, e.g. emission of cathode
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
A camera 63 captures a surface image of a sample. A criterion position setting processing unit 101 varies the focal position of laser light relative to the sample, which is located on a stage, and sets the focal position for which the spot area of the laser light in the surface image satisfies a prescribed first criterion as a criterion position. An assessment processing unit 102 varies the focal position in the depth direction relative to the criterion position and, on the basis of a change in the spot position of the laser light in the surface image, assesses whether or not the amount of light impinging on slits 29, 30 provided in front of a detector 50 satisfies a prescribed second criterion. An angle adjustment processing unit 103 adjusts the angle of a mirror 15 if it is assessed that the amount of light impinging on the slits 29, 30 does not satisfy the prescribed second criterion.
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