Zeltiq Aesthetics, Inc.

United States of America

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2024 January 1
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IPC Class
A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body 84
A61F 7/02 - Compresses or poultices for effecting heating or cooling 38
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques 34
A61F 7/10 - Cooling bags, e.g. ice-bags 28
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body 24
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10 - Medical apparatus and instruments 22
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services 14
35 - Advertising and business services 2
38 - Telecommunications services 2
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1.

COOLING DEVICE HAVING A PLURALITY OF CONTROLLABLE COOLING ELEMENTS TO PROVIDE A PREDETERMINED COOLING PROFILE

      
Application Number 18216423
Status Pending
Filing Date 2023-06-29
First Publication Date 2024-02-29
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse N.
  • Pennybacker, William P.

Abstract

A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/10 - Cooling bags, e.g. ice-bags

2.

TREATMENT SYSTEMS AND METHODS FOR AFFECTING GLANDS AND OTHER TARGETED STRUCTURES

      
Application Number 18143555
Status Pending
Filing Date 2023-05-04
First Publication Date 2024-01-04
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Debenedictis, Leonard
  • Frangineas, Jr., George
  • Tatsutani, Kristine
  • Weber, Bryan J.
  • Jiang, Kerrie
  • Yee, Peter
  • Pham, Linda
  • Nanda, Gurvinder Singh

Abstract

Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 1/00 - Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones 
  • A61N 7/00 - Ultrasound therapy
  • A61K 31/045 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
  • A61K 31/047 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

3.

TREATMENT SYSTEMS, SMALL VOLUME APPLICATORS, AND METHODS FOR TREATING SUBMENTAL TISSUE

      
Application Number 18161746
Status Pending
Filing Date 2023-01-30
First Publication Date 2023-10-12
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Yee, Peter
  • Coakley, Joseph
  • Frangineas, Jr., George
  • Hilton, Tamara

Abstract

Systems for treating a subject's tissue can include a thermally conductive cup, a tissue-receiving cavity, and a vacuum port. The vacuum port is in fluid communication with the tissue-receiving cavity to provide a vacuum for drawing the submental tissue, or other targeted tissue, into the tissue-receiving cavity. A thermal device can cool and/or heat the conductive cup such that the conductive cup non-invasively controls the temperature of subcutaneous lipid-rich cells in the tissue. A restraint apparatus can hold a the conductive cup in thermal contact with the target region.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 90/14 - Fixators for body parts, e.g. skull clamps; Constructional details of fixators, e.g. pins

4.

USE OF SACCHARIDES FOR CRYOPROTECTION AND RELATED TECHNOLOGY

      
Application Number 18092928
Status Pending
Filing Date 2023-01-03
First Publication Date 2023-09-14
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Jimenez Lozano, Joel N.
  • Debenedictis, Leonard C.
  • Zeng, Like
  • Frangineas, Jr., George

Abstract

A method in accordance with a particular embodiment of the present invention includes increasing a concentration of a modified or unmodified saccharide within a subject's skin, applying an applicator to the subject's skin, and cooling the subject's skin via a heat-transfer surface of the applicator. The saccharide within the subject's skin can enhance a resistance of at least some cells within the subject's skin to damage associated with the cooling. A corresponding system includes the applicator, the saccharide, and an energy-delivery device. The energy-delivery device can be configured to apply ultrasound, optical, thermal, or another type of energy to the subject's skin to drive the saccharide into the subject's skin. The system can also include a penetration enhancer configured to enhance penetration of the saccharide into the subject's skin. The penetration enhancer can be applied with the saccharide or separately.

IPC Classes  ?

  • A61K 8/60 - Sugars; Derivatives thereof
  • A61N 1/30 - Apparatus for iontophoresis or cataphoresis
  • A61K 8/42 - Amides
  • A61K 8/36 - Carboxylic acids; Salts or anhydrides thereof
  • A61K 8/86 - Polyethers
  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • C07H 3/04 - Disaccharides
  • A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61N 7/00 - Ultrasound therapy

5.

MONITORING THE COOLING OF SUBCUTANEOUS LIPID-RICH CELLS, SUCH AS THE COOLING OF ADIPOSE TISSUE

      
Application Number 18103424
Status Pending
Filing Date 2023-01-30
First Publication Date 2023-09-07
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse Nicasio
  • Hinton, Corydon A.
  • Springer, Kevin S.

Abstract

A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event.

IPC Classes  ?

  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 9/00 - Pneumatic or hydraulic massage
  • A61H 23/02 - Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

6.

TRANSCUTANEOUS TREATMENT SYSTEMS, COOLING DEVICES, AND METHODS FOR COOLING NERVES

      
Application Number 17874902
Status Pending
Filing Date 2022-07-27
First Publication Date 2023-03-23
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Frangineas, Jr., George
  • Debenedictis, Leonard C.

Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin and other treatments are described. Aspects of the technology are directed to improving the appearance of skin by transcutaneously cooling and affecting nerve tissue so as to inhibit facial muscular contractions and thereby reduce dynamic wrinkling. A non-invasive nerve cooling device can be applied to the subject's head to attenuate nervous system signals to facial muscles.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons

7.

Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue

      
Application Number 16865245
Grant Number 11583438
Status In Force
Filing Date 2020-05-01
First Publication Date 2023-02-21
Grant Date 2023-02-21
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse Nicasio
  • Hinton, Corydon A.
  • Springer, Kevin S.

Abstract

A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event.

IPC Classes  ?

  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61H 23/02 - Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
  • A61H 9/00 - Pneumatic or hydraulic massage
  • A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets

8.

METHODS, DEVICES, AND SYSTEMS FOR IMPROVING SKIN CHARACTERISTICS

      
Application Number 17873064
Status Pending
Filing Date 2022-07-25
First Publication Date 2023-02-16
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Jimenez Lozano, Joel N.
  • Zeng, Like
  • Pham, Linda
  • Frangineas, Jr., George

Abstract

Provided herein are systems, compositions, and methods for improving one or more skin characteristics in a subject. These systems, compositions, and methods are configured to cool the subject's skin at a target site to a degree that alters adipocyte signaling but does not produce significant destruction of subcutaneous lipid-rich cells. In some embodiments, alteration of adipocyte signaling produces an improvement in one or more skin characteristics.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

9.

TREATMENT SYSTEMS WITH FLUID MIXING SYSTEMS AND FLUID-COOLED APPLICATORS AND METHODS OF USING THE SAME

      
Application Number 17843898
Status Pending
Filing Date 2022-06-17
First Publication Date 2023-02-09
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Weber, Bryan J.
  • Coakley, Joseph
  • Baker, Mark William
  • Reeve, Iii, Thomas Burnell

Abstract

A treatment system for cooling subcutaneous lipid-rich cells in a human subject includes an applicator and a control unit. The treatment system has a cooling mode for cooling tissue and a heating mode for warming tissue. The control unit includes a circulation circuit in fluid communication with the applicator, a chiller apparatus configured to chill fluid from the applicator circulation circuit, and a heater apparatus to warmed fluid from the applicator circulation circuit. The control unit mixes the chilled fluid and/or the warmed with fluid in the applicator circulation circuit control the temperature of the fluid circulated in the applicator.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

10.

PHASE ADJUSTED COIL EXCITATION FOR MUSCLE STIMULATION

      
Application Number 17530447
Status Pending
Filing Date 2021-11-18
First Publication Date 2022-05-19
Owner ZELTIQ Aesthetics, Inc. (USA)
Inventor
  • Frangineas, Jr., George
  • Zeng, Like
  • Jimenez Lozano, Joel N.

Abstract

Systems and methods can be implemented in which an electromagnetic charge is used to strengthen, tone, and firm muscle tissues. For example, the method may include receiving parameters for operation of a magnetic muscle stimulation device. The method may also include causing, based on the received parameters, a first alternating current having a first phase to flow through a first coil and generate a first time-varying magnetic field that induces a first electric charge in muscle tissue under a skin surface of a patient when the first applicator surface is positioned substantially on and parallel to the skin surface of the patient. The method may also include causing a second alternating current having a second phase to flow through a second coil in a similar manner. Optionally, a phase offset between the first and second phases may be adjusted to limit to a predetermined maximum electric charge.

IPC Classes  ?

  • A61N 2/00 - Magnetotherapy
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

11.

DELIVERY OF ELECTROMAGNETIC CHARGE TO MUSCLES

      
Application Number 17530318
Status Pending
Filing Date 2021-11-18
First Publication Date 2022-05-19
Owner ZELTIQ Aesthetics, Inc. (USA)
Inventor
  • Frangineas, Jr., George
  • Zeng, Like
  • Jimenez Lozano, Joel N.

Abstract

Systems and methods can be implemented in which an electromagnetic charge is used to strengthen, tone, and firm muscle tissues. For example, a magnetic muscle stimulation device may be provided that includes a processor and a device applicator having a housing and a coil positioned within in the housing. The processor may be configured to receive parameters for operation of the device applicator, and to cause, based on the received parameters, an alternating current to flow through the coil to generate a time-varying magnetic field that induces an integrated electric charge or electrical conductivity in a portion of tissue under a skin surface of a patient.

IPC Classes  ?

  • A61N 1/04 - Electrodes
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61N 2/00 - Magnetotherapy

12.

MULTI-APPLICATOR SYSTEM AND METHOD FOR BODY CONTOURING

      
Document Number 03188869
Status Pending
Filing Date 2021-08-13
Open to Public Date 2022-02-17
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Baker, Mark William
  • Coakley, Joseph
  • Frangineas, George Jr.
  • Gauthier, Russell Lee
  • Gomes, Roy Christopher
  • Heke, Clive
  • Kordes, Kurt Arthur
  • Mccall, Mark Allen
  • Pennybacker, William P.
  • Root, Austin
  • Saunders, Ralph Edward
  • Stivers, Teri L.
  • Yee, Peter

Abstract

Systems, methods, and devices for treating a subject are described herein. In some embodiments, an applicator for selectively affecting a subject's subcutaneous tissue is provided. The applicator can include: a housing; a treatment cup mounted in the housing, wherein the treatment cup defines a tissue-receiving cavity and includes a temperature-controlled surface; at least one thermal device coupled to the treatment cup and configured to receive energy via a flexible connector coupled to the applicator and to cool the temperature-controlled surface; an at least one vacuum port coupled to the treatment cup and configured to provide a vacuum to draw the subject's tissue into the tissue-receiving cavity and against at least a portion of a treatment area of the temperature-controlled surface to selectively damage and/or reduce the subject's subcutaneous tissue.

IPC Classes  ?

  • A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

13.

MULTI-APPLICATOR SYSTEM AND METHOD FOR BODY CONTOURING

      
Application Number 17402354
Status Pending
Filing Date 2021-08-13
First Publication Date 2022-02-17
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Baker, Mark William
  • Coakley, Joseph
  • Frangineas, Jr., George
  • Gauthier, Russell Lee
  • Gomes, Roy Christopher
  • Heke, Clive
  • Kordes, Kurt Arthur
  • Mccall, Mark Allen
  • Pennybacker, William P.
  • Root, Austin
  • Saunders, Ralph Edward
  • Stivers, Teri L.
  • Yee, Peter

Abstract

Systems, methods, and devices for treating a subject are described herein. In some embodiments, an applicator for selectively affecting a subject's subcutaneous tissue is provided. The applicator can include: a housing; a treatment cup mounted in the housing, wherein the treatment cup defines a tissue-receiving cavity and includes a temperature-controlled surface; at least one thermal device coupled to the treatment cup and configured to receive energy via a flexible connector coupled to the applicator and to cool the temperature-controlled surface; an at least one vacuum port coupled to the treatment cup and configured to provide a vacuum to draw the subject's tissue into the tissue-receiving cavity and against at least a portion of a treatment area of the temperature-controlled surface to selectively damage and/or reduce the subject's subcutaneous tissue.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques

14.

MULTI-APPLICATOR SYSTEM AND METHOD FOR BODY CONTOURING

      
Application Number US2021046023
Publication Number 2022/036271
Status In Force
Filing Date 2021-08-13
Publication Date 2022-02-17
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Baker, Mark, William
  • Coakley, Joseph
  • Frangineas, George, Jr.
  • Gauthier, Russell, Lee
  • Gomes, Roy, Christopher
  • Heke, Clive
  • Kordes, Kurt, Arthur
  • Mccall, Mark, Allen
  • Pennybacker, William, P.
  • Root, Austin
  • Saunders, Ralph, Edward
  • Stivers, Teri, L.
  • Yee, Peter

Abstract

Systems, methods, and devices for treating a subject are described herein. In some embodiments, an applicator for selectively affecting a subject's subcutaneous tissue is provided. The applicator can include: a housing; a treatment cup mounted in the housing, wherein the treatment cup defines a tissue-receiving cavity and includes a temperature-controlled surface; at least one thermal device coupled to the treatment cup and configured to receive energy via a flexible connector coupled to the applicator and to cool the temperature-controlled surface; an at least one vacuum port coupled to the treatment cup and configured to provide a vacuum to draw the subject's tissue into the tissue-receiving cavity and against at least a portion of a treatment area of the temperature-controlled surface to selectively damage and/or reduce the subject's subcutaneous tissue.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current

15.

SHALLOW SURFACE CRYOTHERAPY APPLICATORS AND RELATED TECHNOLOGY

      
Application Number 17350972
Status Pending
Filing Date 2021-06-17
First Publication Date 2022-02-10
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Yee, Peter
  • Frangineas, Jr., George
  • Root, Austin

Abstract

Systems for treating a subject's tissue can include a thermally conductive cup with vacuum features configured to facilitate removal of air located between the cup and the subject's skin. The vacuum features can extend along cup to provide airflow paths to a vacuum port. The applicator can cool and/or heat the retained tissue to affect targeted tissue. After the treat period, the vacuum can be reduced or stop and the applicator can be removed from the subject.

IPC Classes  ?

  • A61B 17/30 - Surgical pincettes
  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

16.

Compositions, treatment systems and methods for improved cooling of lipid-rich tissue

      
Application Number 17143163
Grant Number 11819257
Status In Force
Filing Date 2021-01-07
First Publication Date 2021-09-16
Grant Date 2023-11-21
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • O'Neil, Michael P.
  • Debenedictis, Leonard C.
  • Frangineas, Jr., George

Abstract

Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 1/00 - Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones 
  • A61N 7/00 - Ultrasound therapy
  • A61K 31/045 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
  • A61K 31/047 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

17.

ALTERNATING HIGH FREQUENCY AND LOW FREQUENCY DUTY CYCLES FOR MUSCLE STIMULATION

      
Document Number 03158589
Status Pending
Filing Date 2020-11-20
Open to Public Date 2021-05-27
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Frangineas, George Jr.
  • Caberg, Theodorus Johannes Virginia

Abstract

Muscle tissues can be strengthened, toned, and firmed using a magnetic muscle stimulation device. The device can operate based on a first waveform frequency, one or more pulse durations, a second waveform frequency that is non-zero. Operation of the device can be based on a first alternating current, having one or more first pulses, that flows for a first length of time through a coil according to the first waveform frequency. Further, operation of the device can also be based on a second alternating current, having one or more second pulses, that flows through the coil for a second length of time according to the second waveform frequency, which can be lower than the first waveform frequency. The device can also be operated by repeating the causing of the first and second alternating currents for a plurality of iterations to provide a continuously pulsed time-varying magnetic field that alternates between the first and the second waveform frequencies to generate a treatment session.

IPC Classes  ?

  • A61N 1/40 - Applying electric fields by inductive or capacitive coupling
  • A61N 2/00 - Magnetotherapy
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

18.

ALTERNATING HIGH FREQUENCY AND LOW FREQUENCY DUTY CYCLES FOR MUSCLE STIMULATION

      
Application Number US2020061663
Publication Number 2021/102365
Status In Force
Filing Date 2020-11-20
Publication Date 2021-05-27
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Frangineas, George, Jr.
  • Caberg, Theodorus Johannes Virginia

Abstract

Muscle tissues can be strengthened, toned, and firmed using a magnetic muscle stimulation device. The device can operate based on a first waveform frequency, one or more pulse durations, a second waveform frequency that is non-zero. Operation of the device can be based on a first alternating current, having one or more first pulses, that flows for a first length of time through a coil according to the first waveform frequency. Further, operation of the device can also be based on a second alternating current, having one or more second pulses, that flows through the coil for a second length of time according to the second waveform frequency, which can be lower than the first waveform frequency. The device can also be operated by repeating the causing of the first and second alternating currents for a plurality of iterations to provide a continuously pulsed time-varying magnetic field that alternates between the first and the second waveform frequencies to generate a treatment session.

IPC Classes  ?

  • A61N 1/40 - Applying electric fields by inductive or capacitive coupling
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61N 2/00 - Magnetotherapy

19.

ALTERNATING HIGH FREQUENCY AND LOW FREQUENCY DUTY CYCLES FOR MUSCLE STIMULATION

      
Application Number 17100725
Status Pending
Filing Date 2020-11-20
First Publication Date 2021-05-20
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Frangineas, Jr., George
  • Caberg, Theodorus Johannes Virginia

Abstract

A method for strengthening, toning, and firming muscle tissues, the method includes receiving parameters for operating a magnetic muscle stimulation device. The parameters include: a first waveform frequency; one or more pulse durations; a second waveform frequency that is non-zero; causing, a first alternating current having one or more first pulses to flow for a first length of time through a coil according to the first waveform frequency; causing, a second alternating current having one or more second pulses to flow through the coil for a second length of time according to the second waveform frequency lower than the first waveform frequency. The method includes repeating the causing of the first and second alternating currents for a plurality of iterations to provide a continuously pulsed time-varying magnetic field that alternates between the first and the second waveform frequencies to generate a treatment session.

IPC Classes  ?

  • A61N 2/00 - Magnetotherapy
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

20.

Treatment systems with adjustable gap applicators and methods for cooling tissue

      
Application Number 14710407
Grant Number 10952891
Status In Force
Filing Date 2015-05-12
First Publication Date 2021-03-23
Grant Date 2021-03-23
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Yee, Peter
  • Frangineas, Jr., George
  • Jiang, Kerrie
  • Weber, Bryan J.

Abstract

A system for treating a subject can include an adjustable vacuum applicator configured to receive the subject's tissue by applying a vacuum. The vacuum applicator can have an cavity adjustment mechanism with different modes for widening and narrowing a tissue-receiving cavity to adjust the thermal contact between the vacuum applicator and the subject's tissue within the applicator. Sidewalls of the vacuum applicator can be moved to positive draft angle positions to help draw tissue deeper into the tissue-receiving cavity.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)

21.

COOLING CUP APPLICATORS WITH CONTOURED HEADS AND LINER ASSEMBLIES

      
Application Number 16945789
Status Pending
Filing Date 2020-07-31
First Publication Date 2021-02-18
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Root, Austin
  • Pennybacker, William
  • Frangineas, Jr., George
  • Heke, Clive
  • Debenedictis, Leonard C.

Abstract

Systems for treating a subject's tissue can include a thermally conductive cup, a sealing member, and/or a liner assembly. The systems can include an applicator capable of being reconfigured for a particular treatment site. Components of the applicator can be replaced to achieve a desired configuration. The replaceable components can include contoured heads, liners, and/or sensors. The applicator can draw a vacuum to install various components and/or draw tissue into the applicator. The applicator can cool and/or heat the tissue to affect targeted tissue.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

22.

DEVICES, APPLICATION SYSTEMS AND METHODS WITH LOCALIZED HEAT FLUX ZONES FOR REMOVING HEAT FROM SUBCUTANEOUS LIPID-RICH CELLS

      
Application Number 16905889
Status Pending
Filing Date 2020-06-18
First Publication Date 2020-12-10
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Weber, Bryan
  • Coakley, Joseph
  • Potosky, John

Abstract

Application systems, disposable interface assemblies and methods for cooling subcutaneous lipid-rich tissue. One embodiment of an application system includes a cooling unit, a cryoprotectant vessel, a contact member and an array of selectively addressable heating elements. The cryoprotectant vessel is configured to contain a fluidic cryoprotectant such that at least a portion of the cryoprotectant is cooled by the cooling unit to a desired base temperature. The contact member is attached to the cryoprotectant vessel and includes a backside in contact with the cryoprotectant and a front side opposite the backside. The contact member is configured to allow the cryoprotectant to flow from the backside to the front side. The array of selectively addressable heating elements is carried by the contact member.

IPC Classes  ?

  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

23.

Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile

      
Application Number 16992097
Grant Number 11219549
Status In Force
Filing Date 2020-08-13
First Publication Date 2020-11-26
Grant Date 2022-01-11
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse N.
  • Pennybacker, William P.

Abstract

A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

24.

Device, system and method of removing heat from subcutaneous lipid-rich cells

      
Application Number 16992099
Grant Number 11452634
Status In Force
Filing Date 2020-08-13
First Publication Date 2020-11-26
Grant Date 2022-09-27
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Baker, Mark William
  • Coakley, Joseph
  • Martens, Paul William
  • Ollerdessen, Albert L.
  • Pennybacker, William Patrick
  • Rosen, Jesse N.
  • Yee, Peter
  • Allison, John M.

Abstract

Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

25.

COOLNET

      
Application Number 1561033
Status Registered
Filing Date 2020-10-13
Registration Date 2020-10-13
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ?
  • 35 - Advertising and business services
  • 38 - Telecommunications services
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Medical cooperative advertising, marketing and business consulting services. Providing online medical forum services. Online computer database services in the field of medical information.

26.

COOLING DEVICES WITH FLEXIBLE SENSORS

      
Application Number 16824530
Status Pending
Filing Date 2020-03-19
First Publication Date 2020-07-09
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Levinson, Mitchell
  • Rosen, Jesse N.

Abstract

A device for exchanging heat with a subject having skin is provided. The device includes a heat exchanging member having a heat transfer surface configured to form a heat conducting interface with the subject's skin. The device further includes a substantially flexible sensing device disposed in the interface between the heat exchanging member and the subject's skin. The sensing device is configured to measure a parameter of the interface without substantially impeding heat transfer between the heat exchanging member and the subject's skin.

IPC Classes  ?

  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • G05D 23/24 - Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature the sensing element having a resistance varying with temperature, e.g. thermistor
  • G05D 23/22 - Control of temperature characterised by the use of electric means with sensing elements having variation of electric or magnetic properties with change of temperature the sensing element being a thermocouple
  • G05D 23/19 - Control of temperature characterised by the use of electric means
  • A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons

27.

COOLSCULPTING ELITE

      
Application Number 1537756
Status Registered
Filing Date 2020-05-27
Registration Date 2020-05-27
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical devices, namely, apparatus for tissue cooling, body shaping and contouring, and treatment of cellulite and soft tissue; medical devices used to destroy fat cells.

28.

Treatment systems, devices, and methods for cooling targeted tissue

      
Application Number 14662181
Grant Number 10675176
Status In Force
Filing Date 2015-03-18
First Publication Date 2020-06-09
Grant Date 2020-06-09
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Coakley, Joseph
  • Pennybacker, William P.
  • Weber, Bryan J.

Abstract

Treatment systems include conformable applicators for performing cryotherapy are described. Aspects of the technology are further directed to methods and conformable applicators capable of affecting target regions. The conformable applicators can be applied a wide range of treatment sites. A strap assembly can hold applicator against the treatment site, and a holder assembly can be adhered to the subject's skin to inhibit, limit, or substantially prevent movement of the applicator along the subject's skin.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

29.

COOLSCULPTING ELITE

      
Application Number 203633900
Status Registered
Filing Date 2020-05-27
Registration Date 2023-05-31
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

(1) Medical devices, namely, medical apparatus consisting of a control unit and connected applicator applied to the body for non-invasively and minimally-invasively cooling body tissue, body shaping and body contouring, and improving the appearance of cellulite and soft tissue; medical devices namely medical apparatus consisting of a control unit and connected applicator applied to the body for non-invasively and minimally-invasively destroying body fat cells and removing body fat.

30.

CRYOPROTECTANT FOR USE WITH A TREATMENT DEVICE FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH CELLS

      
Application Number 16595466
Status Pending
Filing Date 2019-10-08
First Publication Date 2020-05-21
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell E.
  • Johnson, Donald
  • Preciado, Jessica
  • Ebbers, Edward A.
  • Bucks, Daniel

Abstract

A cryoprotectant for use with a treatment device for improved removal of heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cryoprotectant is a non-freezing liquid, gel, or paste for allowing pre-cooling of the treatment device below 0° C. while preventing the formation of ice thereon. The cryoprotectant may also prevent freezing of the treatment device to the skin or ice from forming from moisture seeping out from the skin. The cryoprotectant may further be hygroscopic, thermally conductive, and biocompatible.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
  • A61B 18/20 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser

31.

TEMPERATURE-DEPENDENT ADHESION BETWEEN APPLICATOR AND SKIN DURING COOLING OF TISSUE

      
Application Number 16693273
Status Pending
Filing Date 2019-11-23
First Publication Date 2020-04-02
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Debenedictis, Leonard C.
  • Zeng, Like
  • Frangineas, Jr., George
  • Jimenez Lozano, Joel N.

Abstract

A method and apparatus in accordance with a particular embodiment of the present invention includes applying adhesive onto skin of a human subject. An applicator is then brought into contact with the adhesive such the adhesive is disposed between the applicator and the subject's skin. The applicator is activated to cool a tissue region via the subject's skin, via the heat-transfer surface of the applicator, and via the adhesive. While the tissue region cools, the adhesive also cools, thereby reversibly strengthening adhesion between the subject's skin and the heat-transfer surface and forming a strong bond therebetween. The strengthened adhesion inhibits any movement of the applicator relative to the skin. After cooling the tissue region, the adhesive is warmed, thereby weakening the adhesion which allows the heat-transfer surface of the applicator to be easily separated from the skin.

IPC Classes  ?

  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

32.

COMPOSITIONS, TREATMENT SYSTEMS, AND METHODS FOR FRACTIONALLY FREEZING TISSUE

      
Application Number 16557814
Status Pending
Filing Date 2019-08-30
First Publication Date 2020-03-05
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor Pham, Linda

Abstract

Compositions and formulations having one or more anti-freeze proteins for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Embodiments of the technology are further directed to methods, compositions having one or more anti-freeze proteins and devices that protect non-targeted cells from freeze damage during dermatological and related aesthetic procedures requiring sustained exposure to cold temperatures. Further embodiments of the technology include systems for enhancing sustained and/or replenishing release of a freezing point depressant having one or more anti-freeze proteins to a treatment site prior to and during cooling applications.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61M 35/00 - Devices for applying media, e.g. remedies, on the human body

33.

Methods, devices, and systems for improving skin characteristics

      
Application Number 16528249
Grant Number 11446175
Status In Force
Filing Date 2019-07-31
First Publication Date 2020-02-06
Grant Date 2022-09-20
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Jimenez Lozano, Joel N.
  • Zeng, Like
  • Pham, Linda
  • Frangineas, Jr., George

Abstract

Provided herein are systems, compositions, and methods for improving one or more skin characteristics in a subject. These systems, compositions, and methods are configured to cool the subject's skin at a target site to a degree that alters adipocyte signaling but does not produce significant destruction of subcutaneous lipid-rich cells. In some embodiments, alteration of adipocyte signaling produces an improvement in one or more skin characteristics.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

34.

METHODS, DEVICES, AND SYSTEMS FOR IMPROVING SKIN CHARACTERISTICS

      
Application Number US2019044304
Publication Number 2020/028472
Status In Force
Filing Date 2019-07-31
Publication Date 2020-02-06
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Jimenez Lozano, Joel N.
  • Zeng, Like
  • Pham, Linda
  • Frangineas, George, Jr.

Abstract

Provided herein are systems, compositions, and methods for improving one or more skin characteristics in a subject. These systems, compositions, and methods are configured to cool the subject's skin at a target site to a degree that alters adipocyte signaling but does not produce significant destruction of subcutaneous lipid-rich cells. In some embodiments, alteration of adipocyte signaling produces an improvement in one or more skin characteristics.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/10 - Cooling bags, e.g. ice-bags

35.

METHODS, DEVICES, AND SYSTEMS FOR IMPROVING SKIN CHARACTERISTICS

      
Document Number 03107932
Status Pending
Filing Date 2019-07-31
Open to Public Date 2020-02-06
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Jimenez Lozano, Joel N.
  • Zeng, Like
  • Pham, Linda
  • Frangineas, George, Jr.

Abstract

Provided herein are systems, compositions, and methods for improving one or more skin characteristics in a subject. These systems, compositions, and methods are configured to cool the subject's skin at a target site to a degree that alters adipocyte signaling but does not produce significant destruction of subcutaneous lipid-rich cells. In some embodiments, alteration of adipocyte signaling produces an improvement in one or more skin characteristics.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/10 - Cooling bags, e.g. ice-bags

36.

COOLTONE

      
Application Number 1502303
Status Registered
Filing Date 2019-10-21
Registration Date 2019-10-21
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical devices, namely, therapeutic apparatus and instruments generating high frequency electromagnetic energy for use in muscle stimulation, treatment of cellulite and soft tissue, and sculpting, shaping and contouring of the body; medical devices, namely, medical apparatus and instruments generating high frequency electromagnetic energy for use in electrical muscle stimulation for medical purposes, treatment of cellulite, and treatment of soft tissue by means of electrical nerve stimulation for medical purposes.

37.

Treatment apparatus for removing heat from subcutaneous lipid-rich cells and massaging tissue

      
Application Number 16542182
Grant Number 11291606
Status In Force
Filing Date 2019-08-15
First Publication Date 2019-12-05
Grant Date 2022-04-05
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Rosen, Jesse Nicasio
  • Levinson, Mitchell E.

Abstract

A treatment device for removing heat from subcutaneous lipid-rich cells of a subject having an actuator that provides mechanical energy to the tissue. The mechanical energy provided may include a vibratory component that can range between low and ultra-high frequencies, and such energy may include various combinations of two or more frequencies tailored to produce the desired effect on the subcutaneous tissue. Disruption of adipose tissue cooled by an external treatment device may be enhanced by applying mechanical energy to cooled tissue. Furthermore, such mechanical energy may impart a vibratory effect, a massage effect, a pulsatile effect, or combinations thereof on the tissue.

IPC Classes  ?

  • A61H 9/00 - Pneumatic or hydraulic massage
  • A61H 7/00 - Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 23/02 - Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive

38.

Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile

      
Application Number 16415684
Grant Number 11179269
Status In Force
Filing Date 2019-05-17
First Publication Date 2019-11-07
Grant Date 2021-11-23
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse N.
  • Pennybacker, William P.

Abstract

A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

39.

COOLTONE

      
Application Number 199950700
Status Registered
Filing Date 2019-10-21
Registration Date 2021-07-07
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

(1) Medical devices, namely, therapeutic apparatus and instruments generating high frequency electromagnetic energy for use in muscle stimulation, treatment of cellulite and soft tissue, and sculpting, shaping and contouring of the body; medical devices, namely, medical apparatus and instruments generating high frequency electromagnetic energy for use in electrical muscle stimulation for medical purposes, treatment of cellulite, and treatment of soft tissue by means of electrical nerve stimulation for medical purposes.

40.

COOLSCULPTING ELITE

      
Serial Number 88649777
Status Registered
Filing Date 2019-10-10
Registration Date 2022-05-31
Owner Zeltiq Aesthetics, Inc. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical devices, namely, apparatus for tissue cooling, body shaping and contouring, and treatment of cellulite and soft tissue; medical devices used to destroy fat cells

41.

COOLMINI

      
Application Number 196128700
Status Registered
Filing Date 2019-05-06
Registration Date 2021-08-26
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

(1) Medical devices, namely, apparatus for tissue cooling, contouring and cellulite improvement; medical devices used to destroy fat cells

42.

COOLTONE

      
Application Number 196128800
Status Registered
Filing Date 2019-05-06
Registration Date 2021-08-26
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

(1) Medical devices, namely, apparatus and instruments generating high frequency electromagnetic energy for use in muscle stimulation, treatment of cellulite and soft tissue, and sculpting, shaping and contouring of the body

43.

Treatment systems, methods, and apparatuses for improving the appearance of skin and providing other treatments

      
Application Number 16233951
Grant Number 10806500
Status In Force
Filing Date 2018-12-27
First Publication Date 2019-05-02
Grant Date 2020-10-20
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Debenedictis, Leonard C.
  • Frangineas, Jr., George
  • Tatsutani, Kristine
  • Pham, Linda

Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 1/00 - Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones 
  • A61N 7/00 - Ultrasound therapy
  • A61K 31/045 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
  • A61K 31/047 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

44.

COOLMINI

      
Application Number 1454027
Status Registered
Filing Date 2019-01-03
Registration Date 2019-01-03
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical devices, namely, apparatus for tissue cooling, contouring and cellulite improvement; medical devices used to destroy fat cells.

45.

COOLTONE

      
Serial Number 88266308
Status Registered
Filing Date 2019-01-17
Registration Date 2020-10-06
Owner Zeltiq Aesthetics, Inc. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical devices, namely, therapeutic apparatus and instruments generating high frequency electromagnetic energy for use in muscle stimulation, treatment of cellulite and soft tissue, and sculpting, shaping and contouring of the body; Medical devices, namely, medical apparatus and instruments generating high frequency electromagnetic energy for use in electrical muscle stimulation for medical purposes, treatment of cellulite, and treatment of soft tissue by means of electrical nerve stimulation for medical purposes

46.

Shallow surface cryotherapy applicators and related technology

      
Application Number 15962811
Grant Number 11076879
Status In Force
Filing Date 2018-04-25
First Publication Date 2018-11-01
Grant Date 2021-08-03
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Yee, Peter
  • Frangineas, Jr., George
  • Root, Austin

Abstract

Systems for treating a subject's tissue can include a thermally conductive cup with vacuum features configured to facilitate removal of air located between the cup and the subject's skin. The vacuum features can extend along cup to provide airflow paths to a vacuum port. The applicator can cool and/or heat the retained tissue to affect targeted tissue. After the treat period, the vacuum can be reduced or stop and the applicator can be removed from the subject.

IPC Classes  ?

  • A61B 17/30 - Surgical pincettes
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

47.

USE OF SACCHARIDES FOR CRYOPROTECTION AND RELATED TECHNOLOGY

      
Application Number US2018021391
Publication Number 2018/175111
Status In Force
Filing Date 2018-03-07
Publication Date 2018-09-27
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Jimenez Lozano, Joel, N.
  • Debenedictis, Leonard, C.
  • Zeng, Like
  • Frangineas, George

Abstract

A method in accordance with a particular embodiment of the present invention includes increasing a concentration of a modified or unmodified saccharide within a subject's skin, applying an applicator to the subject's skin, and cooling the subject's skin via a heat- transfer surface of the applicator. The saccharide within the subject's skin can enhance a resistance of at least some cells within the subject's skin to damage associated with the cooling. A corresponding system includes the applicator, the saccharide, and an energy- delivery device. The energy-delivery device can be configured to apply ultrasound, optical, thermal, or another type of energy to the subject's skin to drive the saccharide into the subject's skin. The system can also include a penetration enhancer configured to enhance penetration of the saccharide into the subject's skin. The penetration enhancer can be applied with the saccharide or separately.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

48.

Compositions, treatment systems and methods for improved cooling of lipid-rich tissue

      
Application Number 15833329
Grant Number 10912599
Status In Force
Filing Date 2017-12-06
First Publication Date 2018-07-05
Grant Date 2021-02-09
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • O'Neil, Michael P.
  • Debenedictis, Leonard C.
  • Frangineas, Jr., George

Abstract

Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 1/00 - Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones 
  • A61N 7/00 - Ultrasound therapy
  • A61K 31/045 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
  • A61K 31/047 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

49.

Device, system and method of removing heat from subcutaneous lipid-rich cells

      
Application Number 15847688
Grant Number 11224536
Status In Force
Filing Date 2017-12-19
First Publication Date 2018-06-14
Grant Date 2022-01-18
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Baker, Mark William
  • Coakley, Joseph
  • Martens, Paul William
  • Ollerdessen, Albert L.
  • Pennybacker, William Patrick
  • Rosen, Jesse N.
  • Yee, Peter
  • Allison, John W.

Abstract

Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

50.

Treatment apparatus for removing heat from subcutaneous lipid-rich cells and massaging tissue

      
Application Number 15815454
Grant Number 10383787
Status In Force
Filing Date 2017-11-16
First Publication Date 2018-06-07
Grant Date 2019-08-20
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Rosen, Jesse Nicasio
  • Levinson, Mitchell E.

Abstract

A treatment device for removing heat from subcutaneous lipid-rich cells of a subject having an actuator that provides mechanical energy to the tissue. The mechanical energy provided may include a vibratory component that can range between low and ultra-high frequencies, and such energy may include various combinations of two or more frequencies tailored to produce the desired effect on the subcutaneous tissue. Disruption of adipose tissue cooled by an external treatment device may be enhanced by applying mechanical energy to cooled tissue. Furthermore, such mechanical energy may impart a vibratory effect, a massage effect, a pulsatile effect, or combinations thereof on the tissue.

IPC Classes  ?

  • A61H 9/00 - Pneumatic or hydraulic massage
  • A61H 7/00 - Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61H 23/02 - Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive

51.

Hydrogel substances and methods of cryotherapy

      
Application Number 15499349
Grant Number 10555831
Status In Force
Filing Date 2017-04-27
First Publication Date 2017-11-16
Grant Date 2020-02-11
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Jimenez Lozano, Joel N.
  • Debenedictis, Leonard C.

Abstract

A method and system in accordance with particular embodiments includes applying a substance onto skin of a human subject. A method for treating a subject's skin includes applying a hydrogel to the skin which contains the substance. The hydrogel and the skin are cooled using a cooling applicator to treat tissue via the cooling treatment by either freezing or not freezing tissue.

IPC Classes  ?

  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

52.

Skin freezing systems for treating acne and skin conditions

      
Application Number 15499534
Grant Number 11382790
Status In Force
Filing Date 2017-04-27
First Publication Date 2017-11-16
Grant Date 2022-07-12
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Debenedictis, Leonard C.
  • Jimenez Lozano, Joel N.
  • Zeng, Like
  • Frangineas, Jr., George
  • Pham, Linda

Abstract

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. An applicator is then applied to the subject to cool a region of the subject. After cooling the tissue, a nucleation initiator is used to initiate a freeze event in the tissue. The nucleation initiator can be an ice crystal that inoculates the skin upon contact to create a predictable freeze event therein. The time of contact between the ice crystal and the skin can be controlled to achieve desired effects.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61K 9/06 - Ointments; Bases therefor
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

53.

Liposomes, emulsions, and methods for cryotherapy

      
Application Number 15498867
Grant Number 10682297
Status In Force
Filing Date 2017-04-27
First Publication Date 2017-11-16
Grant Date 2020-06-16
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Zeng, Like
  • Jimenez Lozano, Joel N.
  • Debenedictis, Leonard C.

Abstract

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. The applied substance can include a freezing point depressant and a liposome, an oil-in-water emulsion, a water-in-oil emulsion, or an oil-in-oil emulsion and can be configured to protect or target tissue. The substance and a surface of the skin can be cooled using the applicator to treat acne and other skin conditions.

IPC Classes  ?

  • A61K 8/14 - Liposomes
  • A61K 8/34 - Alcohols
  • A61Q 19/06 - Preparations for care of the skin for countering cellulitis
  • A61Q 19/08 - Anti-ageing preparations
  • A61Q 19/00 - Preparations for care of the skin
  • A61K 9/127 - Liposomes
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61P 17/10 - Anti-acne agents
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/107 - Emulsions
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

54.

SKIN FREEZING SYSTEMS FOR TREATING ACNE AND SKIN CONDITIONS

      
Application Number US2017029887
Publication Number 2017/196548
Status In Force
Filing Date 2017-04-27
Publication Date 2017-11-16
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Debenedictis, Leonard, C.
  • Jiminez Lozano, Joel, N.
  • Zeng, Like
  • Frangineas, Jr., George
  • Pham, Linda, D.

Abstract

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. An applicator is then applied to the subject to cool a region of the subject. After cooling the tissue, a nucleation initiator is used to initiate a freeze event in the tissue. The nucleation initiator can be an ice crystal that inoculates the skin upon contact to create a predictable freeze event therein. The time of contact between the ice crystal and the skin can be controlled to achieve desired effects.

IPC Classes  ?

  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

55.

Cooling cup applicators with contoured heads and liner assemblies

      
Application Number 15435179
Grant Number 10765552
Status In Force
Filing Date 2017-02-16
First Publication Date 2017-08-24
Grant Date 2020-09-08
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Root, Austin
  • Pennybacker, William
  • Frangineas, George
  • Heke, Clive
  • Debenedictis, Leonard C.

Abstract

Systems for treating a subject's tissue can include a thermally conductive cup, a sealing member, and/or a liner assembly. The systems can include an applicator capable of being reconfigured for a particular treatment site. Components of the applicator can be replaced to achieve a desired configuration. The replaceable components can include contoured heads, liners, and/or sensors. The applicator can draw a vacuum to install various components and/or draw tissue into the applicator. The applicator can cool and/or heat the tissue to affect targeted tissue.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

56.

TEMPERATURE-DEPENDENT ADHESION BETWEEN APPLICATOR AND SKIN DURING COOLING OF TISSUE

      
Document Number 03009414
Status Pending
Filing Date 2017-01-06
Open to Public Date 2017-07-13
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Debenedictis, Leonard C.
  • Zeng, Like
  • Frangineas, George, Jr.
  • Jimenez Lozano, Joel N.

Abstract

A method and apparatus in accordance with a particular embodiment of the present invention includes applying adhesive onto skin of a human subject. An applicator is then brought into contact with the adhesive such the adhesive is disposed between the applicator and the subject's skin. The applicator is activated to cool a tissue region via the subject's skin, via the heat-transfer surface of the applicator, and via the adhesive. While the tissue region cools, the adhesive also cools, thereby reversibly strengthening adhesion between the subject's skin and the heat-transfer surface and forming a strong bond therebetween. The strengthened adhesion inhibits any movement of the applicator relative to the skin. After cooling the tissue region, the adhesive is warmed, thereby weakening the adhesion which allows the heat-transfer surface of the applicator to be easily separated from the skin.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

57.

TEMPERATURE-DEPENDENT ADHESION BETWEEN APPLICATOR AND SKIN DURING COOLING OF TISSUE

      
Application Number US2017012626
Publication Number 2017/120538
Status In Force
Filing Date 2017-01-06
Publication Date 2017-07-13
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Debenedictis, Leonard, C.
  • Zeng, Like
  • Frangineas, George, Jr.
  • Jimenez Lozano, Joel, N.

Abstract

A method and apparatus in accordance with a particular embodiment of the present invention includes applying adhesive onto skin of a human subject. An applicator is then brought into contact with the adhesive such the adhesive is disposed between the applicator and the subject's skin. The applicator is activated to cool a tissue region via the subject's skin, via the heat-transfer surface of the applicator, and via the adhesive. While the tissue region cools, the adhesive also cools, thereby reversibly strengthening adhesion between the subject's skin and the heat-transfer surface and forming a strong bond therebetween. The strengthened adhesion inhibits any movement of the applicator relative to the skin. After cooling the tissue region, the adhesive is warmed, thereby weakening the adhesion which allows the heat-transfer surface of the applicator to be easily separated from the skin.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 13/02 - Adhesive plasters or dressings
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

58.

Temperature-dependent adhesion between applicator and skin during cooling of tissue

      
Application Number 15400885
Grant Number 10524956
Status In Force
Filing Date 2017-01-06
First Publication Date 2017-07-13
Grant Date 2020-01-07
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Debenedictis, Leonard C.
  • Zeng, Like
  • Frangineas, Jr., George
  • Jimenez Lozano, Joel N.

Abstract

A method and apparatus in accordance with a particular embodiment of the present invention includes applying adhesive onto skin of a human subject. An applicator is then brought into contact with the adhesive such the adhesive is disposed between the applicator and the subject's skin. The applicator is activated to cool a tissue region via the subject's skin, via the heat-transfer surface of the applicator, and via the adhesive. While the tissue region cools, the adhesive also cools, thereby reversibly strengthening adhesion between the subject's skin and the heat-transfer surface and forming a strong bond therebetween. The strengthened adhesion inhibits any movement of the applicator relative to the skin. After cooling the tissue region, the adhesive is warmed, thereby weakening the adhesion which allows the heat-transfer surface of the applicator to be easily separated from the skin.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

59.

VASCULAR TREATMENT SYSTEMS, COOLING DEVICES, AND METHODS FOR COOLING VASCULAR STRUCTURES

      
Application Number US2016057535
Publication Number 2017/070112
Status In Force
Filing Date 2016-10-18
Publication Date 2017-04-27
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor Frangineas, George

Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin and other treatments are described. Aspects of the technology are directed to improving the appearance of skin by reducing a vascular structure. A non-invasive cooling device can cover and cool the vascular structure to affect the blood vessels of the vascular structure.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques

60.

Vascular treatment systems, cooling devices, and methods for cooling vascular structures

      
Application Number 15296853
Grant Number 11154418
Status In Force
Filing Date 2016-10-18
First Publication Date 2017-04-20
Grant Date 2021-10-26
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor Frangineas, Jr., George

Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin and other treatments are described. Aspects of the technology are directed to improving the appearance of skin by reducing a vascular structure. A non-invasive cooling device can cover and cool the vascular structure to affect the blood vessels of the vascular structure.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

61.

TRANSCUTANEOUS TREATMENT SYSTEMS AND COOLING DEVICES

      
Application Number US2016052713
Publication Number 2017/053324
Status In Force
Filing Date 2016-09-20
Publication Date 2017-03-30
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Frangineas, George, Jr.
  • Debenedictis, Leonard, C.

Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin and other treatments are described. Aspects of the technology are directed to improving the appearance of skin by transcutaneously cooling and affecting nerve tissue so as to inhibit facial muscular contractions and thereby reduce dynamic wrinkling. A non-invasive nerve cooling device can be applied to the subject's head to attenuate nervous system signals to facial muscles.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

62.

Cryotherapy applicator for cooling tissue

      
Application Number 29485645
Grant Number D0777338
Status In Force
Filing Date 2014-03-20
First Publication Date 2017-01-24
Grant Date 2017-01-24
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Coakley, Joseph
  • Pennybacker, William

63.

Treatment systems and methods for affecting glands and other targeted structures

      
Application Number 15115503
Grant Number 10575890
Status In Force
Filing Date 2015-01-30
First Publication Date 2017-01-12
Grant Date 2020-03-03
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Debenedictis, Leonard
  • Frangineas, Jr., George
  • Tatsutani, Kristine
  • Weber, Bryan J.
  • Jiang, Kerrie
  • Yee, Peter
  • Pham, Linda
  • Nanda, Gurvinder Singh

Abstract

Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 1/00 - Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones 
  • A61N 7/00 - Ultrasound therapy
  • A61K 31/045 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
  • A61K 31/047 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

64.

Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue

      
Application Number 15194338
Grant Number 10675178
Status In Force
Filing Date 2016-06-27
First Publication Date 2016-11-10
Grant Date 2020-06-09
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse Nicasio
  • Hinton, Corydon A.
  • Springer, Kevin S.

Abstract

A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event.

IPC Classes  ?

  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 9/00 - Pneumatic or hydraulic massage
  • A61H 23/02 - Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets

65.

TREATMENT SYSTEMS, METHODS, AND APPARATUSES FOR ALTERING THE APPEARANCE OF SKIN

      
Application Number US2015050217
Publication Number 2016/048721
Status In Force
Filing Date 2015-09-15
Publication Date 2016-03-31
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Debenedictis, Leonard, C.
  • Frangineas, George, Jr.

Abstract

Systems and methods that enable tissue cooling and delivery of energy for altering tissue are described herein. Aspects of the disclosure are directed to, for example, heating tissue at treatment zones to ablate, denature, reorganize, coagulate, or otherwise alter the tissue to affect the cosmetic appearance of the patient. The method can include, for example, removing heat from the target region of the human subject before, during, and/or after energy delivery to cool tissue to a temperature below normal body temperature to inhibit pain.

IPC Classes  ?

  • A61N 7/02 - Localised ultrasound hyperthermia
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 18/20 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61N 5/06 - Radiation therapy using light
  • A61N 5/067 - Radiation therapy using light using laser light
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques

66.

Stress relief couplings for cryotherapy apparatuses

      
Application Number 14829424
Grant Number 10935174
Status In Force
Filing Date 2015-08-18
First Publication Date 2016-02-25
Grant Date 2021-03-02
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Pennybacker, William P.
  • Carson, Craig

Abstract

Systems, devices, and methods for treating a patient are disclosed. The systems can include a cryotherapy apparatus for selectively treating targeted tissue. The cryotherapy apparatus includes one or more stress relief couplings located along a conduit to help keep an applicator positioned at a treatment site without significant rotational torque being imparted to the applicator by the conduit so that the applicator does not tend to move relative to patient skin during a tissue treatment. The stress relief couplings can include swivel connectors and clamps that cooperate to minimize or limit a rotational force exerted on the applicator by the conduit after the applicator is applied to the patient's skin.

IPC Classes  ?

  • A61B 18/14 - Probes or electrodes therefor
  • F16L 27/02 - Universal joints, i.e. with mechanical connection allowing angular movement or adjustment of the axes of the parts in any direction
  • A61M 39/10 - Tube connectors or tube couplings
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

67.

TREATMENT SYSTEMS, SMALL VOLUME APPLICATORS, AND METHODS FOR TREATING SUBMENTAL TISSUE

      
Application Number US2015045714
Publication Number 2016/028796
Status In Force
Filing Date 2015-08-18
Publication Date 2016-02-25
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Yee, Peter
  • Coakley, Joseph
  • Frangineas, George, Jr.
  • Hilton, Tamara, Lynn

Abstract

Systems for treating a subject's tissue can include a thermally conductive cup, a tissue-receiving cavity, and a vacuum port. The vacuum port is in fluid communication with the tissue-receiving cavity to provide a vacuum for drawing the submental tissue, or other targeted tissue, into the tissue-receiving cavity. A thermal device can cool and/or heat the conductive cup such that the conductive cup non-invasively controls the temperature of subcutaneous lipid-rich cells in the tissue. A restraint apparatus can hold a the conductive cup in thermal contact with the target region.

IPC Classes  ?

  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

68.

Treatment systems, small volume applicators, and methods for treating submental tissue

      
Application Number 14705868
Grant Number 10568759
Status In Force
Filing Date 2015-05-06
First Publication Date 2016-02-25
Grant Date 2020-02-25
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Yee, Peter
  • Coakley, Joseph
  • Frangineas, Jr., George
  • Hilton, Tamara

Abstract

Systems for treating a subject's tissue can include a thermally conductive cup, a tissue-receiving cavity, and a vacuum port. The vacuum port is in fluid communication with the tissue-receiving cavity to provide a vacuum for drawing the submental tissue, or other targeted tissue, into the tissue-receiving cavity. A thermal device can cool and/or heat the conductive cup such that the conductive cup non-invasively controls the temperature of subcutaneous lipid-rich cells in the tissue. A restraint apparatus can hold a the conductive cup in thermal contact with the target region.

IPC Classes  ?

  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

69.

Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile

      
Application Number 14825841
Grant Number 10292859
Status In Force
Filing Date 2015-08-13
First Publication Date 2015-12-03
Grant Date 2019-05-21
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse N.
  • Pennybacker, William P.

Abstract

A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 18/14 - Probes or electrodes therefor

70.

Tissue treatment methods

      
Application Number 14808245
Grant Number 11395760
Status In Force
Filing Date 2015-07-24
First Publication Date 2015-11-19
Grant Date 2022-07-26
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor Levinson, Mitchell E.

Abstract

Methods are provided herein for affecting a region of a subject's body, comprising exposing the region to a cooling element under conditions effective to cool subcutaneous adipose tissue in said region; and increasing the blood flow rate to the cooled tissue by exposing the tissue to an energy source. Methods are also provided for treating subcutaneous adipose tissue in a region of a subject's body, comprising exposing said region to a cooling element under conditions effective to cool said tissue; and exposing the tissue to an energy source to increase the blood flow rate to the cooled tissue, thereby stimulating reperfusion in, and/or causing an ischemia-reperfusion injury to, the cooled tissue.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 18/14 - Probes or electrodes therefor
  • A61H 1/00 - Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones 

71.

COOLMINI

      
Serial Number 86799546
Status Registered
Filing Date 2015-10-26
Registration Date 2016-06-14
Owner Zeltiq Aesthetics, Inc. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

medical devices, namely, apparatus for tissue cooling, contouring and cellulite improvement; medical devices used to destroy fat cells

72.

Treatment systems, methods, and apparatuses for improving the appearance of skin and providing other treatments

      
Application Number 14611127
Grant Number 10201380
Status In Force
Filing Date 2015-01-30
First Publication Date 2015-08-06
Grant Date 2019-02-12
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Debenedictis, Leonard C.
  • Frangineas, Jr., George
  • Tatsutani, Kristine
  • Pham, Linda

Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 1/00 - Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones 
  • A61N 7/00 - Ultrasound therapy
  • A61K 31/045 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
  • A61K 31/047 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

73.

COMPOSITIONS, TREATMENT SYSTEMS AND METHODS FOR IMPROVED COOLING OF LIPID-RICH TISSUE

      
Application Number US2015013912
Publication Number 2015/117001
Status In Force
Filing Date 2015-01-30
Publication Date 2015-08-06
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • O'Neil, Michael P.
  • Debenedictis, Leonard C.
  • Frangineas, George, Jr.

Abstract

Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)

74.

Compositions, treatment systems and methods for improved cooling of lipid-rich tissue

      
Application Number 14610807
Grant Number 09861421
Status In Force
Filing Date 2015-01-30
First Publication Date 2015-08-06
Grant Date 2018-01-09
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • O'Neil, Michael P.
  • Debenedictis, Leonard C.
  • Frangineas, Jr., George

Abstract

Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61H 1/00 - Apparatus for passive exercising; Vibrating apparatus; Chiropractic devices, e.g. body impacting devices, external devices for briefly extending or aligning unbroken bones 
  • A61N 7/00 - Ultrasound therapy
  • A61K 31/045 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
  • A61K 31/047 - Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

75.

TREATING SYSTEMS FOR TREATING CELLULITE BY COOLING

      
Application Number US2015013959
Publication Number 2015/117026
Status In Force
Filing Date 2015-01-30
Publication Date 2015-08-06
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Debenedictis, Leonard, C.
  • Frangineas, George, Jr.
  • Tatsutani, Kristine
  • Pham, Linda

Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance sites with cellulite. Treatments can include cooling a surface of a patient's skin and detecting freezing in the cooled skin. The tissue can be cooled after the freeze event is detected so to maintain the frozen state of the tissue to improve the appearance of the treatment site.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)

76.

TREATMENT SYSTEMS AND METHODS FOR AFFECTING GLANDS AND OTHER TARGETED STRUCTURES

      
Application Number US2015013971
Publication Number 2015/117032
Status In Force
Filing Date 2015-01-30
Publication Date 2015-08-06
Owner ZELTIQ AESTHESTICS, INC. (USA)
Inventor
  • Debenedictis, Leonard, C.
  • Frangineas, George, Jr.
  • Tatsutani, Kristine
  • Weber, Bryan, J.
  • Jiang, Kerrie
  • Yee, Peter
  • Pham, Linda
  • Nanda, Gurvinder, Singh

Abstract

Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

77.

TREATMENT SYSTEMS, METHODS, AND APPARATUSES FOR IMPROVING THE APPEARANCE OF SKIN AND PROVIDING FOR OTHER TREATMENTS

      
Application Number US2015013985
Publication Number 2015/117036
Status In Force
Filing Date 2015-01-30
Publication Date 2015-08-06
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Debenedictis, Leonard C.
  • Frangineas, George, Jr.
  • Tatsutani, Kristine
  • Pham, Linda

Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

78.

Combined modality treatment systems, methods and apparatus for body contouring applications

      
Application Number 14185054
Grant Number 10092346
Status In Force
Filing Date 2014-02-20
First Publication Date 2014-10-23
Grant Date 2018-10-09
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor Levinson, Mitchell E.

Abstract

Systems and methods that enable delivery of radiofrequency energy and cryotherapy applications to adipose tissue for reduction and contouring of body fat are described herein. Aspects of the disclosure are directed to methods for reducing surface irregularities in a surface of a subject's skin resulting from an uneven distribution of adipose tissue in the subcutaneous layer. The method can include delivering capacitively coupled or conductively coupled radiofrequency energy to a target region of the subject at a frequency which selectively heats fibrous septae in a subcutaneous layer of the target region to a maximum temperature less than a fibrous septae denaturation temperature. Furthermore, the method can include removing heat such that lipid-rich lobules in the subcutaneous layer are affected while non-lipid-rich cells and lipid-rich regions adjacent to the fibrous septae are not substantially affected.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

79.

MULTI-MODALITY TREATMENT SYSTEMS, METHODS AND APPARATUS FOR ALTERING SUBCUTANEOUS LIPID-RICH TISSUE

      
Application Number US2014026558
Publication Number 2014/151850
Status In Force
Filing Date 2014-03-13
Publication Date 2014-09-25
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor Nanda, Gurvinder, Singh

Abstract

Systems and methods that enable tissue cooling applications and delivery of electrical energy to adipose tissue for alteration and reduction of body fat are described herein. Aspects of the disclosure are directed to, for example, temperature-controlled electroporation of subcutaneous lipid-rich cells. Additional aspects of the disclosure are directed to treatment methods for treating a target region of a human subject's body to achieve an alteration of subcutaneous adipose tissue. The method can include, for example, removing heat from the target region of the human subject during a treatment process to cool subcutaneous lipid-rich cells in the target region to a temperature below normal body temperature. Furthermore, the method can include delivering energy to the target region to produce an electric field in an amount sufficient to create pores in membranes of the subcutaneous lipid-rich cells that have been cooled to the temperature below normal body temperature.

IPC Classes  ?

  • A61N 1/04 - Electrodes
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

80.

TREATMENT SYSTEMS WITH FLUID MIXING SYSTEMS AND FLUID-COOLED APPLICATORS AND METHODS OF USING THE SAME

      
Application Number US2014026596
Publication Number 2014/151872
Status In Force
Filing Date 2014-03-13
Publication Date 2014-09-25
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Weber, Bryan, J.
  • Coakley, Joseph
  • Baker, Mark, William
  • Reeve, Thomas, Burnell

Abstract

A treatment system for cooling subcutaneous lipid-rich cells in a human subject includes an applicator and a control unit. The treatment system has a cooling mode for cooling tissue and a heating mode for warming tissue. The control unit includes a circulation circuit in fluid communication with the applicator, a chiller apparatus configured to chill fluid from the applicator circulation circuit, and a heater apparatus to warmed fluid from the applicator circulation circuit. The control unit mixes the chilled fluid and/or the warmed with fluid in the applicator circulation circuit control the temperature of the fluid circulated in the applicator.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

81.

Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same

      
Application Number 13830027
Grant Number 09844460
Status In Force
Filing Date 2013-03-14
First Publication Date 2014-09-18
Grant Date 2017-12-19
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Weber, Bryan J.
  • Coakley, Joseph
  • Baker, Mark William
  • Reeve, Iii, Thomas Burnell

Abstract

A treatment system for cooling subcutaneous lipid-rich cells in a human subject includes an applicator and a control unit. The treatment system has a cooling mode for cooling tissue and a heating mode for warming tissue. The control unit includes a circulation circuit in fluid communication with the applicator, a chiller apparatus configured to chill fluid from the applicator circulation circuit, and a heater apparatus to warmed fluid from the applicator circulation circuit. The control unit mixes the chilled fluid and/or the warmed with fluid in the applicator circulation circuit control the temperature of the fluid circulated in the applicator.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

82.

Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue

      
Application Number 13830413
Grant Number 09545523
Status In Force
Filing Date 2013-03-14
First Publication Date 2014-09-18
Grant Date 2017-01-17
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor Nanda, Gurvinder Singh

Abstract

Systems and methods that enable tissue cooling applications and delivery of electrical energy to adipose tissue for alteration and reduction of body fat are described herein. Aspects of the disclosure are directed to, for example, temperature-controlled electroporation of subcutaneous lipid-rich cells. Additional aspects of the disclosure are directed to treatment methods for treating a target region of a human subject's body to achieve an alteration of subcutaneous adipose tissue. The method can include, for example, removing heat from the target region of the human subject during a treatment process to cool subcutaneous lipid-rich cells in the target region to a temperature below normal body temperature. Furthermore, the method can include delivering energy to the target region to produce an electric field in an amount sufficient to create pores in membranes of the subcutaneous lipid-rich cells that have been cooled to the temperature below normal body temperature.

IPC Classes  ?

  • A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents
  • A61N 1/40 - Applying electric fields by inductive or capacitive coupling
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 18/14 - Probes or electrodes therefor
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

83.

Device, system and method of removing heat from subcutaneous lipid-rich cells

      
Application Number 14205794
Grant Number 09861520
Status In Force
Filing Date 2014-03-12
First Publication Date 2014-09-11
Grant Date 2018-01-09
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Baker, Mark William
  • Coakley, Joseph
  • Martens, Paul William
  • Ollerdessen, Albert L.
  • Pennybacker, William Patrick
  • Rosen, Jesse N.
  • Yee, Peter
  • Allison, John W.

Abstract

Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

84.

System for treating lipid-rich regions

      
Application Number 13960723
Grant Number 09655770
Status In Force
Filing Date 2013-08-06
First Publication Date 2014-03-06
Grant Date 2017-05-23
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse Nicasio
  • Hinton, Corydon A.

Abstract

A system is described for removing heat from a subject's subcutaneous lipid-rich regions, such as tissues, organs, cells, and so forth. In various embodiments, the system includes a controller, a computing device, a data acquisition device, a chiller, and one or more applicators. The system can employ these components to receive a selection of a treatment profile and apply the selected treatment using an applicator. The treatment profile may be received from a patient protection device that connects to an applicator.

IPC Classes  ?

  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • H04L 29/06 - Communication control; Communication processing characterised by a protocol
  • A61B 90/98 - Identification means for patients or instruments, e.g. tags using electromagnetic means, e.g. transponders
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61F 7/12 - Devices for heating or cooling internal body cavities
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

85.

FEAR NO MIRROR

      
Application Number 165648900
Status Registered
Filing Date 2013-12-16
Registration Date 2015-08-25
Owner ZELTIQ AESTHETICS, INC. (DELAWARE CORPORATION) (USA)
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

(1) Medical services, namely, procedures and services consisting of using non-invasive and minimally-invasive medical devices and apparatus applied to the body to improve the appearance of cellulite, remove fat, and provide body contouring.

86.

COOLCONNECT

      
Serial Number 86077009
Status Registered
Filing Date 2013-09-27
Registration Date 2017-04-18
Owner Zeltiq Aesthetics, Inc. ()
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Computer hardware and software for collecting, processing and transmitting medical device usage data to a central repository via telecommunication and global computer networks for analysis, storage and remote access Providing an on-line computer database featuring medical information

87.

Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells

      
Application Number 13888168
Grant Number 09737434
Status In Force
Filing Date 2013-05-06
First Publication Date 2013-09-19
Grant Date 2017-08-22
Owner Zeltiq Aestehtics, Inc. (USA)
Inventor Allison, John W.

Abstract

Systems for removing heat from a subject's subcutaneous lipid-rich regions, such as tissue, organs, cells, and so forth, are described herein. In various embodiments, the system includes a treatment device and a controller for controlling a treatment process. The controller is configured to detect and compensate for an interruption in the treatment process.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

88.

Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile

      
Application Number 13616186
Grant Number 09375345
Status In Force
Filing Date 2012-09-14
First Publication Date 2013-05-09
Grant Date 2016-06-28
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell
  • Rosen, Jesse N.
  • Pennybacker, William

Abstract

A cooling device for removing heat from subcutaneous lipid-rich cells of a subject having skin is provided. The cooling device includes a plurality of cooling elements movable relative to each other to conform to the contour's of the subject's skin. The cooling elements have a plurality of controllable thermoelectric coolers. The cooling elements can be controlled to provide a time-varying cooling profile in a predetermined sequence, can be controlled to provide a spatial cooling profile in a selected pattern, or can be adjusted to maintain constant process parameters, or can be controlled to provide a combination thereof.

IPC Classes  ?

  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61B 18/14 - Probes or electrodes therefor
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

89.

Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue

      
Application Number 13616391
Grant Number 09408745
Status In Force
Filing Date 2012-09-14
First Publication Date 2013-05-09
Grant Date 2016-08-09
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Levinson, Mitchell E.
  • Rosen, Jesse Nicasio
  • Hinton, Corydon A.
  • Springer, Kevin S.

Abstract

A system and method of monitoring, controlling and/or detecting events during the removal of heat from subcutaneous lipid-rich tissue is described. In some examples, the system detects an increase in temperature at a treatment device in contact with the skin of a subject, determines that the increase in temperature is related to a treatment event, and performs an action based on the determination. In some examples, the system shuts off the treatment device, alerts an operator, or reduces the cooling in response to a determined treatment event.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
  • A61H 9/00 - Pneumatic or hydraulic massage
  • A61H 23/02 - Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive

90.

DUALSCULPTING

      
Application Number 161051300
Status Registered
Filing Date 2013-01-18
Registration Date 2015-12-21
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

(1) Medical services, specifically plastic surgery services, namely procedures and services in the nature of tissue contouring and cellulite improvement.

91.

FREEZE DETECT

      
Application Number 011358702
Status Registered
Filing Date 2012-11-20
Registration Date 2013-04-23
Owner Zeltiq Aesthetics, Inc. (USA)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

medical apparatus, namely, patient tissue condition measurement and monitoring system consisting of thermal sensors and algorithmic software, sold as integral component of medical devices used to destroy fat cells and for tissue cooling, contouring and cellulite improvement.

92.

FREEZE DETECT

      
Serial Number 85782998
Status Registered
Filing Date 2012-11-19
Registration Date 2013-08-27
Owner Zeltiq Aesthetics, Inc. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical apparatus, namely, patient tissue condition measurement and monitoring system consisting of thermal sensors and algorithmic software, sold as an integral component of medical devices used to destroy fat cells and for tissue cooling, contouring and cellulite improvement

93.

Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells

      
Application Number 13358337
Grant Number 10722395
Status In Force
Filing Date 2012-01-25
First Publication Date 2012-09-20
Grant Date 2020-07-28
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Weber, Bryan
  • Coakley, Joseph
  • Potosky, John

Abstract

Application systems, disposable interface assemblies and methods for cooling subcutaneous lipid-rich tissue. One embodiment of an application system includes a cooling unit, a cryoprotectant vessel, a contact member and an array of selectively addressable heating elements. The cryoprotectant vessel is configured to contain a fluidic cryoprotectant such that at least a portion of the cryoprotectant is cooled by the cooling unit to a desired base temperature. The contact member is attached to the cryoprotectant vessel and includes a backside in contact with the cryoprotectant and a front side opposite the backside. The contact member is configured to allow the cryoprotectant to flow from the backside to the front side. The array of selectively addressable heating elements is carried by the contact member.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

94.

DEVICES, APPLICATION SYSTEMS AND METHODS WITH LOCALIZED HEAT FLUX ZONES FOR REMOVING HEAT FROM SUBCUTANEOUS LIPID-RICH CELLS

      
Application Number US2012022585
Publication Number 2012/103242
Status In Force
Filing Date 2012-01-25
Publication Date 2012-08-02
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Weber, Bryan
  • Coakley, Joseph
  • Potosky, John

Abstract

Application systems, disposable interface assemblies and methods for cooling subcutaneous lipid-rich tissue. One embodiment of an application system includes a cooling unit, a cryoprotectant vessel, a contact member and an array of selectively addressable heating elements. The cryoprotectant vessel is configured to contain a fluidic cryoprotectant such that at least a portion of the cryoprotectant is cooled by the cooling unit to a desired base temperature. The contact member is attached to the cryoprotectant vessel and includes a backside in contact with the cryoprotectant and a front side opposite the backside. The contact member is configured to allow the cryoprotectant to flow from the backside to the front side. The array of selectively addressable heating elements is carried by the contact member.

IPC Classes  ?

  • A61F 7/10 - Cooling bags, e.g. ice-bags
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling

95.

Combined modality treatment systems, methods and apparatus for body contouring applications

      
Application Number 12840235
Grant Number 08676338
Status In Force
Filing Date 2010-07-20
First Publication Date 2012-01-26
Grant Date 2014-03-18
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor Levinson, Mitchell E.

Abstract

Systems and methods that enable delivery of radiofrequency energy and cryotherapy applications to adipose tissue for reduction and contouring of body fat are described herein. Aspects of the disclosure are directed to methods for reducing surface irregularities in a surface of a subject's skin resulting from an uneven distribution of adipose tissue in the subcutaneous layer. The method can include delivering capacitively coupled or conductively coupled radiofrequency energy to a target region of the subject at a frequency which selectively heats fibrous septae in a subcutaneous layer of the target region to a maximum temperature less than a fibrous septae denaturation temperature. Furthermore, the method can include removing heat such that lipid-rich lobules in the subcutaneous layer are affected while non-lipid-rich cells and lipid-rich regions adjacent to the fibrous septae are not substantially affected.

IPC Classes  ?

  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

96.

COMBINED MODALITY TREATMENT SYSTEMS, METHODS AND APPARATUS FOR BODY CONTOURING APPLICATIONS

      
Application Number US2011044270
Publication Number 2012/012296
Status In Force
Filing Date 2011-07-15
Publication Date 2012-01-26
Owner ZEL TIQ AESTHETICS, INC. (USA)
Inventor Levinson, Mitchell, E.

Abstract

Systems and methods that enable delivery of radiofrequency energy and cryotherapy applications to adipose tissue for reduction and contouring of body fat are described herein. Aspects of the disclosure are directed to methods for reducing surface irregularities in a surface of a subject's skin resulting from an uneven distribution of adipose tissue in the subcutaneous layer. The method can include delivering capacitively coupled or conductively coupled radiofrequency energy to a target region of the subject at a frequency which selectively heats fibrous septae in a subcutaneous layer of the target region to a maximum temperature less than a fibrous septae denaturation temperature. Furthermore, the method can include removing heat such that lipid-rich lobules in the subcutaneous layer are affected while non-lipid-rich cells and lipid-rich regions adjacent to the fibrous septae are not substantially affected.

IPC Classes  ?

  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

97.

COOLNET

      
Serial Number 85455403
Status Registered
Filing Date 2011-10-25
Registration Date 2012-10-30
Owner Zeltiq Aesthetics, Inc. ()
NICE Classes  ?
  • 35 - Advertising and business services
  • 38 - Telecommunications services
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Medical cooperative advertising, marketing and business consulting services [ Providing online medical forum services ] Online computer database services in the field of medical information

98.

Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants

      
Application Number 13013603
Grant Number 09844461
Status In Force
Filing Date 2011-01-25
First Publication Date 2011-09-29
Grant Date 2017-12-19
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Levinson, Mitchell E.
  • Allison, John W.
  • Coakley, Joseph
  • Weber, Bryan

Abstract

Home-use applicators for non-invasively removing heat from subcutaneous, lipid-rich cells via phase change coolants, and associated devices, systems and methods. A device in accordance with a particular embodiment includes an applicator releasably positionable in thermal communication with human skin, and a coolant vessel having a coolant. The device further includes a heat transfer conduit operatively coupled to the applicator and housing a heat transfer fluid that is isolated from fluid contact with the coolant. A heat exchanger is operatively coupled between the coolant vessel and the heat transfer conduit to transfer heat between the heat transfer fluid and the coolant, and a fluid driver is operatively coupled to the heat transfer conduit to direct the heat transfer fluid between the applicator and the heat exchanger.

IPC Classes  ?

  • A61F 7/12 - Devices for heating or cooling internal body cavities
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body
  • F28F 7/00 - Elements not covered by group , , or

99.

Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associates devices, systems and methods

      
Application Number 13013579
Grant Number 09314368
Status In Force
Filing Date 2011-01-25
First Publication Date 2011-09-29
Grant Date 2016-04-19
Owner Zeltiq Aesthetics, Inc. (USA)
Inventor
  • Allison, John W.
  • Levinson, Mitchell E.
  • Rosen, Jesse N.

Abstract

Home-use applicators for non-invasively removing heat from subcutaneous, lipid-rich cells via phase change coolants, and associated devices, systems and methods. A device in accordance with a particular embodiment includes an applicator releasably positionable in thermal communication with human skin, and a coolant vessel having a coolant. The device further includes a heat transfer conduit operatively coupled to the applicator and housing a heat transfer fluid that is isolated from fluid contact with the coolant. A heat exchanger is operatively coupled between the coolant vessel and the heat transfer conduit to transfer heat between the heat transfer fluid and the coolant, and a fluid driver is operatively coupled to the heat transfer conduit to direct the heat transfer fluid between the applicator and the heat exchanger.

IPC Classes  ?

  • A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
  • A61F 7/02 - Compresses or poultices for effecting heating or cooling
  • A61F 7/00 - Heating or cooling appliances for medical or therapeutic treatment of the human body

100.

COMPOSITIONS FOR USE WITH A SYSTEM FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH TISSUE

      
Application Number US2011022112
Publication Number 2011/091293
Status In Force
Filing Date 2011-01-21
Publication Date 2011-07-28
Owner ZELTIQ AESTHETICS, INC. (USA)
Inventor
  • Martens, Paul, William
  • Potosky, John

Abstract

A composition or cryoprotectant for use with a system for improved cooling of subcutaneous lipid-rich tissue of a subject having skin is provided. The cryoprotectant is a non-freezing liquid, gel, or paste for allowing pre-cooling of a treatment device below about 00C while preventing the formation of ice thereon. The cryoprotectant may also prevent freezing of the treatment device to the skin and protect tissue of a subject from freezing damage due to, e.g., ice formation. The cryoprotectant can also include an authentication or anti-counterfeiting agent to authenticate an origin of the cryoprotectant, a lubricating agent to increase lubriciousness of the cryoprotectant, and a thixotropic or pseudoplastic agent in an amount effective substantially to render the gel dimensionally stable unless agitated.

IPC Classes  ?

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