Abstract

The aluminum anode alloy consists essentially of an aluminum base and effective amounts of tin and indium. The aluminum alloy is useful as a sacrificial metallic coating, as a protective aluminum anode, and as a pigment in polymeric coatings.

IPC Classes  ?

• C22C 21/00 - Alloys based on aluminium
• C09D 7/61 - Additives non-macromolecular inorganic
• C09D 5/10 - Anti-corrosive paints containing metal dust
• C23F 13/14 - Material for sacrificial anodes
• C23C 30/00 - Coating with metallic material characterised only by the composition of the metallic material, i.e. not characterised by the coating process

Abstract

Compositions including a fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods for treatment and prophylaxis of conditions related to anemic conditions, are provided, including compositions and methods for treating anemic conditions such as hemolytic anemia and anemia of chronic disease, and other related conditions.

IPC Classes  ?

• A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
• A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
• A61P 7/06 - Antianaemics

Abstract

Compositions including an fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods for treatment and prophylaxis of conditions related to inflammation and conditions related to inflammation, including anemia of chronic disease, insulin resistance, metabolic syndrome, autoimmune disease, hypertension, diabetes, nonalcoholic fatty liver disease, cardiovascular disease, cancer, aging, neurodegenerative diseases, including Alzheimer's disease and other forms of dementia, and other related conditions, and other related conditions.

IPC Classes  ?

• A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
• A61P 5/50 - Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
• A61P 7/06 - Antianaemics
• A61P 9/00 - Drugs for disorders of the cardiovascular system
• A61P 25/00 - Drugs for disorders of the nervous system
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
• A61P 35/00 - Antineoplastic agents
• A61P 43/00 - Drugs for specific purposes, not provided for in groups

Abstract

The subject matter of the instant invention relates to methods of compounding compositions comprising bacteriophage effective for treating bacterial infections, including but not limited to, multidrug resistant bacterial infections. The invention also relates to compositions, bacterial diversity sets, and phage libraries prepared according to the methods of the instant invention.

IPC Classes  ?

• A61K 35/76 - Viruses; Subviral particles; Bacteriophages
• C12N 7/00 - Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA

Abstract

An exemplary welding consumable according to the invention is provided and includes up to about 0.13 wt % carbon, about 0.3 wt % to about 1.4 wt % manganese, about 7.25 wt% to about 11.5 wt % nickel, about 0.6 wt % to about 1.2 wt % molybdenum, about 0.2 wt % to about 0.7 wt % silicon, up to about 0.3 wt % vanadium, up to about 0.05 wt % titanium, up to about 0.08 wt % zirconium, up to about 2.0 wt % chromium, and a balance of iron and incidental impurities.

IPC Classes  ?

• B23K 35/24 - Selection of soldering or welding materials proper

Abstract

The inventive subject matter relates to a construct comprising antigens derived from multiple enterobacteria including Campylobacter jejuni capsule polysaccharide polymer, enterotoxigenic Escherichia coli recombinant polypeptide construct and lipopolysaecharide from Shigella spp.. The subject invention also relates to a method of inducing an immune response utilizing the inventive composition.

IPC Classes  ?

• A61K 39/385 - Haptens or antigens, bound to carriers
• A61K 39/116 - Polyvalent bacterial antigens
• A61P 31/04 - Antibacterial agents
• A61P 37/04 - Immunostimulants

Abstract

The inventive subject matter relates to an immunogenic composition against Campylobacter jejuni comprising isolated capsule polysaccharide from selected pathogenic Campylobacter jejuni strains. The inventive subject matter also relates to methods of using the polysaccharide compositions in inducing and anti-C. jejuni immune response.

IPC Classes  ?

• A61K 39/106 - Vibrio; Campylobacter
• A61K 39/385 - Haptens or antigens, bound to carriers
• A61P 31/04 - Antibacterial agents
• A61P 37/04 - Immunostimulants

Abstract

The inventive subject matter relates to a recombinant polypeptide construct comprising enterotoxigenic Escherichia coli fimbrial subunits. The recombinant polypeptide constructs comprise multiple subunits to the same or different ETEC fimbrial types. The constructs are useful for inclusion in immunogenic formulations for the inductin of immunity against entertoxigenic Escherichia coli. The inventive subject matter also relates to the use of the recombinant polypeptide constructs in induce anti- enterotoxigenic Escherichia coli.

IPC Classes  ?

• C07K 14/245 - Escherichia (G)
• A61K 39/108 - Escherichia; Klebsiella
• C12N 15/31 - Genes encoding microbial proteins, e.g. enterotoxins

Abstract

Sacrificial-metal pigments are coated with an effective amount of at least one metal oxide or a combination of metal oxides such as a chromium-zirconium oxide, and the process for preparing said coated pigments and combination thereof with film-forming binders for coating metal substrates to inhibit corrosion. The coated sacrificial-metal pigments are electrically active to prevent corrosion of metal substrates that are more.

IPC Classes  ?

• C23C 22/06 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using aqueous solutions using aqueous acidic solutions with pH < 6
• C09D 5/08 - Anti-corrosive paints
• C23F 11/10 - Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent in other liquids using organic inhibitors

Abstract

This Invention relates to galvanic aluminum alloy powder-figments coated with a semi-conducting corrosion inhibiting oxide ad the process for preparing said coated powder-pigments in combination with film-forming binders for coating metal substrates to inhibit corrosion. The coated aluminium alloy powder-pigments are electrically active aid prevent corrosion of metals which are more catholic (electropositive) than the aluminium alloy pigments;

IPC Classes  ?

• C09C 1/64 - Aluminium
• C09D 5/10 - Anti-corrosive paints containing metal dust
• C23C 22/00 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals
• C23F 11/00 - Inhibiting corrosion of metallic material by applying inhibitors to the surface in danger of corrosion or adding them to the corrosive agent

Abstract

The invention provides novel malaria polypeptides expressed at the preerythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.

IPC Classes  ?

• A61K 39/015 - Hemosporidia antigens, e.g. Plasmodium antigens
• A61P 33/06 - Antimalarials
• A61P 37/04 - Immunostimulants
• C07K 14/445 - Plasmodium
• C12N 15/30 - Genes encoding protozoal proteins, e.g. from Plasmodium, Trypanosoma, Eimeria
• C12N 15/86 - Viral vectors

Abstract

The invention provides novel malaria polypeptides expressed at the pre- erythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.

IPC Classes  ?

• A61K 39/015 - Hemosporidia antigens, e.g. Plasmodium antigens
• A61P 33/02 - Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
• C07K 14/445 - Plasmodium
• C12N 15/30 - Genes encoding protozoal proteins, e.g. from Plasmodium, Trypanosoma, Eimeria
• C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
• C12N 15/86 - Viral vectors

Abstract

An immunogenic composition, and method of using the composition to elicit an immune response to Campylobacter jejuni. The composition is an isolated polysaccharide polymer composed of one or more forms of disaccharide polymers.

IPC Classes  ?

• A61K 39/106 - Vibrio; Campylobacter
• A61K 39/385 - Haptens or antigens, bound to carriers
• A61P 31/04 - Antibacterial agents
• A61P 37/04 - Immunostimulants

Abstract

This invention comprises an acidic aqueous solution for treating metal substrates to improve the adhesion bonding and corrosion protection of the metal surface which comprises effective amounts of water soluble trivalent chromium compounds, fluorozirconates, effective amounts of at least one corrosion inhibitors such as benzotriazole, fluorometallic compounds, zinc compounds, thickeners, surfactants, and at least about 0.001 mole per liter of the acidic solution of a polyhydroxy and/or carboxylic compound as a stabilizing agent for the aqueous solution.

IPC Classes  ?

• C23C 22/34 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using aqueous solutions using aqueous acidic solutions with pH < 6 containing fluorides or complex fluorides
• C23C 22/50 - Treatment of iron or alloys based thereon

Abstract

The inventive subject matter relates to the methods for the induction of immunity and prevention of diarrhea resulting from Escherichia coli. The inventive subject matter also relates to the use Escherichia coli adhesins as immunogens and to the construction of conformationally stability and protease resistant Escherichia coli adhesin constructs useful for inducing immunity to Escherichia coli pathogenic bacteria. The methods provide for the induction of B-cell mediated immunity and for the induction of antibody capable of inhibiting the adherence and colonization of Escherichia.coli, including. enterotoxigenic Escherichia coli, to human cells.

IPC Classes  ?

• A61K 39/108 - Escherichia; Klebsiella

Abstract

Pretreated aluminum and aluminum alloys and the process and composition for pretreating said aluminum and its alloys to provide a coating with color recognition for identification purposes and to improve the corrosion- resistance, electrical conductivity, and adhesion properties which comprises pretreating said aluminum and its alloys with an effective amount of an acidic aqueous solution having a pH ranging from about 2.5 to 5.5 comprising water soluble trivalent chromium compounds, alkali metal hexafluorozirconates, divalent zinc compounds, alkali metal fluoro-compounds, and effective amounts of water soluble thickeners, surfactants or wetting agents.

IPC Classes  ?

• C23C 22/05 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using aqueous solutions
• C23C 22/34 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using aqueous solutions using aqueous acidic solutions with pH < 6 containing fluorides or complex fluorides

Abstract

Aqueous compositions for post treating metal coated substrates such as cadmium- plated steel, and zinc-nickel coated substrates and the process for using said compositions to provide a color recognizable coating and, to improve the corrosion-resistance, abrasion, electrical, and adhesion properties of the coating. The post-treatment composition comprises an acidic aqueous solution having a pH ranging from about 2.5 to 5.5 and contains effective amounts of trivalent chromium compounds, alkali metal hexafluorozirconates, at least one divalent zinc compound, alkali metal fluoro-compounds, and effective amounts of water soluble thickepers, wetting agents or surfactants.

IPC Classes  ?

• C23C 22/05 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using aqueous solutions

Abstract

Solid combustible waste materials are converted into highly efficient fuel by subjecting such materials to size reduction in suitable size-reducing equipment (10, 12). The last piece of the equipment is a mill (14) which pulverizes the waste materials into fine particles having a high surface to mass ratio and forming a highly efficient fuel when these particles are directly injected into a combustion reactor (18) operating at high temperature.

IPC Classes  ?

• F23G 5/02 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels including pretreatment
• F23G 5/08 - Methods or apparatus, e.g. incinerators, specially adapted for combustion of waste or low-grade fuels including supplementary heating

Abstract

An aqueous composition for post-treating metal coated substrates such as cadmium-plated steel or zinc-nickel coated substrates and the process for using said composition to improve the corrosion-resistance, abrasion, and adhesion bonding properties of the metal coatings. The composition comprising an acidic aqueous solution having a pH ranging from about 2.5 to 4.5 containing effective amounts of trivalent chromium salts, an alkali metal hexafluorozirconate, at least one alkali metal fluorocompound, and effective amounts of water soluble thickeners and/or surfactants.

IPC Classes  ?

• C23C 22/34 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using aqueous solutions using aqueous acidic solutions with pH < 6 containing fluorides or complex fluorides

Abstract

Composition for post-treating anodized aluminum and aluminum alloys and the process for using said composition to improve the corrosionresistance, abrasion, and adhesion bonding properties of the anodized aluminum and its alloys. The composition comprises an acidic aqueous solution having a pH ranging from about 2.5 to 4.5 containing effective amounts of trivalent chromium salts, alkali metal hexafluorozirconates, an alkali metal fluoro- compound e.g. fluoroborates and/or fluorosilicates, and effective amounts of water soluble thickeners and surfactants.

IPC Classes  ?

• C25D 11/24 - Chemical after-treatment
• C23C 22/34 - Chemical surface treatment of metallic material by reaction of the surface with a reactive liquid, leaving reaction products of surface material in the coating, e.g. conversion coatings, passivation of metals using aqueous solutions using aqueous acidic solutions with pH < 6 containing fluorides or complex fluorides